Works about NUCLEUS pulposus

Results: 1354

Gastrodin Alleviates Lumbar Intervertebral Disc Degeneration by Suppressing the NF-κB and MAPK Pathways.

Published in:

Cell Biochemistry & Biophysics, 2025, v. 83, n. 2, p. 2009, doi. 10.1007/s12013-024-01612-2

By:

Hu, Huimin;
Xie, Tian

Publication type:

Article

ATF1 and miR-27b-3p drive intervertebral disc degeneration through the PPARG/NF-κB signaling axis.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-08186-6

By:

Guo, Wei;
Mu, Kun;
Geng, Jing-Chao;
Xing, Hai-Yang;
Dong, Yu;
Liu, Wen-Dong;
Wang, Shuan-Chi;
Shi, Jia-Xiao;
Xing, Bao-Rui;
Zhao, Jian-Yong;
Li, Xiao-Ming

Publication type:

Article

Evaluation of Clinical Symptoms of Unilateral S1 Nerve Injury Caused by Disc Herniation the via High Resolution MRI and DTI.

Published in:

Journal of Pain Research, 2025, v. 18, p. 2105, doi. 10.2147/JPR.S507867

By:

Zhang, ChaoYang;
Hao, Wei;
Guo, Xiaobo;
Zhang, Yuna;
Fu, Hao;
Zhang, Jiashan

Publication type:

Article

Durability of Supplemental Nucleus Pulposus Allograft in Patients with Lumbar Discogenic Pain.

Published in:

Journal of Pain Research, 2025, v. 18, p. 1901, doi. 10.2147/JPR.S516571

By:

Costandi, Shrif;
Beall, Douglas P;
Davis, Timothy T;
Amirdelfan, Kasra;
Naidu, Ramana K;
DePalma, Michael J;
Yoon, Edward S;
Fleming, Jacob W;
Block, Jon E;
Mekhail, Nagy

Publication type:

Article

Gubi Decoction Ameliorates Porous Cartilage Endplate in an Intervertebral Disc Degeneration Model Mouse Through Inhibition of NF-κB Activity and Pyroptosis.

Published in:

Journal of Inflammation Research, 2025, v. 18, p. 5293, doi. 10.2147/JIR.S492365

By:

Yao, Sai;
Li, Yanan;
Ruan, Hongfeng;
Wu, Lianguo;
Zeng, Hanbing

Publication type:

Article

Identification and functional validation of ACSL1 as a biomarker regulating ferroptosis in nucleus pulposus cell.

Published in:

Bioscience Reports, 2025, v. 45, n. 4, p. 215, doi. 10.1042/BSR20241414

By:

Yichi Zhou;
Ke Wang;
Min Ren;
Jiebin Wang;
Fanglin Wang;
Bingbing Zhuang;
Lin Chen;
Zhiqiang Zhang;
Changsheng Wang

Publication type:

Article

Relationship between neutrophil lymphocyte ratio and interleukin-17A levels with pain intensity and degree of herniated nucleus pulposus in low back pain patients.

Published in:

Romanian Journal of Neurology, 2025, v. 24, n. 1, p. 5, doi. 10.37897/RJN.2025.1.1

By:

Rambu, Febrina;
Tammasse, Jumraini;
Aulina, Susi;
Wuysang, Audry Devisanty;
Basri, Muhammad Iqbal;
Zainuddin, Andi Alfian

Publication type:

Article

miR-4478 Promotes Ferroptosis of Nucleus Pulposus Cells through Targeting SLC7A11 to Induce IVDD.

Published in:

Folia Biologica (00155500), 2025, v. 71, n. 1, p. 29, doi. 10.14712/fb2025071010029

By:

DONGLIANG GONG;
LONG JIA;
YUHANG WANG;
CHENGWEI XU;
XUXING SUN;
XIAO WU;
XIAOJUN HAN

Publication type:

Article

RBX1 mitigates ferroptosis by inhibiting NCOA4-mediated ferritinophagy and contributes to the attenuation of intervertebral disc degeneration.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06412-7

By:

Zhou, Lu-Ping;
Kang, Liang;
Zhang, Zhi-Gang;
Jia, Chong-Yu;
Zhao, Chen-Hao;
Zhang, Xian-Liang;
Zhang, Hua-Qing;
Zhang, Ren-Jie;
Shen, Cai-Liang

Publication type:

Article

STMN1–IGFBP5 axis induces senescence and extracellular matrix degradation in nucleus pulposus cells: In vivo and in vitro insights.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01220-7

By:

Li, Lei;
Zhang, Guangzhi;
Yang, Zhili;
Cao, Zhenyu;
Wang, Dongxin;
Kang, Xuewen

Publication type:

Article

EZH2-H3K27me3-Mediated Epigenetic Silencing of DKK1 Induces Nucleus Pulposus Cell Pyroptosis in Intervertebral Disc Degeneration by Activating NLRP3 and NAIP/NLRC4.

Published in:

Inflammation, 2025, v. 48, n. 2, p. 902, doi. 10.1007/s10753-024-02096-1

By:

Yao, Qijun;
Lei, Yue;
Zhang, Yongxu;
Chen, Haoran;
Dong, Xiaowei;
Ye, Zhiqiang;
Liang, Haidong

Publication type:

Article

Probable lumbar acute non-compressive nucleus pulposus extrusion in a cat with acute onset paraparesis.

Published in:

Journal of Feline Medicine & Surgery, 2012, v. 14, n. 10, p. 764, doi. 10.1177/1098612X12450110

By:

Chow, Keshuan;
Beatty, Julia A;
Voss, Katja;
Barrs, Vanessa R

Publication type:

Article

Treatment of Intervertebral Disc Degeneration in Wistar Rats with Mesenchymal Stem Cells.

Published in:

Bulletin of Experimental Biology & Medicine, 2020, v. 168, n. 4, p. 578, doi. 10.1007/s10517-020-04756-2

By:

Lykov, A. P.;
Bondarenko, N. A.;
Poveshchenko, O. V.;
Kim, I. I.;
Surovtseva, M. A.;
Sadykova, J. B.;
Semin, P. A.;
Zavjalov, E. L.;
Krivoshapkin, A. L.;
Konenkov, V. I.

Publication type:

Article

Baicalin suppresses interleukin-1β-induced apoptosis, inflammatory response, oxidative stress, and extracellular matrix degradation in human nucleus pulposus cells.

Published in:

Immunopharmacology & Immunotoxicology, 2023, v. 45, n. 4, p. 433, doi. 10.1080/08923973.2023.2165942

By:

Bai, Xiaoliang;
Yao, Mingyan;
Zhu, Xiaojuan;
Lian, Yong;
Zhang, Mingyuan

Publication type:

Article

Progress in understanding the role of cGAS-STING pathway associated with programmed cell death in intervertebral disc degeneration.

Published in:

Cell Death Discovery, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41420-023-01607-7

By:

Wang, Zheng;
Hu, Xinli;
Cui, Peng;
Kong, Chao;
Chen, Xiaolong;
Wang, Wei;
Lu, Shibao

Publication type:

Article

Development and Characterization of a AuNP-Genipin-Viscoelastic Collagen Material.

Published in:

Journal of Biomaterials Applications, 2023, v. 38, n. 1, p. 85, doi. 10.1177/08853282231173115

By:

Bradley, Janae;
Grant, Sheila A;
Grant, David;
Pfeiffer, Ferris M;
Brockman, John

Publication type:

Article

Thermosensitive injectable decellularized nucleus pulposus hydrogel as an ideal biomaterial for nucleus pulposus regeneration.

Published in:

Journal of Biomaterials Applications, 2020, v. 35, n. 2, p. 182, doi. 10.1177/0885328220921328

By:

Yu, Lei;
Sun, Zi-Jie;
Tan, Quan-Chang;
Wang, Shuang;
Wang, Wei-Heng;
Yang, Xiang-Qun;
Ye, Xiao-Jian

Publication type:

Article

Degenerative cervical spine disease: pathogenesis and symptoms.

Published in:

Medical Studies / Studia Medyczne, 2020, v. 36, n. 4, p. 309, doi. 10.5114/ms.2020.102326

By:

Podlewski, Sebastian;
Kłębczyk, Adam;
Radek, Maciej

Publication type:

Article

Senescence in Intervertebral Disc Degeneration: A Comprehensive Analysis Based on Bioinformatic Strategies.

Published in:

Immunity, Inflammation & Disease, 2024, v. 12, n. 11, p. 1, doi. 10.1002/iid3.70072

By:

Zhao, Zijun;
Wang, Yining;
Wang, Zairan;
Zhang, Fan;
Ding, Ze;
Fan, Tao

Publication type:

Article

Fisetin regulates the biological effects of rat nucleus pulposus mesenchymal stem cells under oxidative stress by sirtuin‐1 pathway.

Published in:

Immunity, Inflammation & Disease, 2023, v. 11, n. 5, p. 1, doi. 10.1002/iid3.865

By:

Zhou, Qing;
Zhu, Chao;
Xuan, Anwu;
Zhang, Junyou;
Zhu, Zhenbiao;
Tang, Liang;
Ruan, Dike

Publication type:

Article

Role of lncRNA MAGI2‐AS3 in lipopolysaccharide‐induced nucleus pulposus cells injury by regulating miR‐374b‐5p/interleukin‐10 axis.

Published in:

Immunity, Inflammation & Disease, 2023, v. 11, n. 4, p. 1, doi. 10.1002/iid3.772

By:

Yu, Jiang;
Li, Chengjin

Publication type:

Article

Effect of regulating macrophage polarization phenotype on intervertebral disc degeneration.

Published in:

Immunity, Inflammation & Disease, 2022, v. 10, n. 11, p. 1, doi. 10.1002/iid3.714

By:

Hou, Xuefeng;
Shen, Yucheng;
Sun, Minli;
Zhang, Bing;
Dai, Jiuming;
Chen, Dong;
Liu, Zhidong

Publication type:

Article

Injectable kaempferol-loaded fibrin glue regulates the metabolic balance and inhibits inflammation in intervertebral disc degeneration.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-47375-3

By:

Gao, Wenshuo;
Bao, Jianhang;
Zhang, Yujun;
He, Du;
Zhang, Liangping;
Zhang, Jun;
Pan, Hao;
Wang, Dong

Publication type:

Article

Aging, cell senescence, the pathogenesis and targeted therapies of intervertebral disc degeneration.

Published in:

Frontiers in Pharmacology, 2023, p. 1, doi. 10.3389/fphar.2023.1172920

By:

Jiongnan Xu;
Ting Shao;
Jianfen Lou;
Jun Zhang;
Chen Xia

Publication type:

Article

Microbicidal Phagocytosis of Nucleus Pulposus Cells Against Staphylococcus aureus via the TLR2/MAPKs Signaling Pathway.

Published in:

Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2019.01132

By:

Lin, Yazhou;
Cong, Hui;
Liu, Kewei;
Jiao, Yucheng;
Yuan, Ye;
Tang, Guoqing;
Chen, Yong;
Zheng, Yuehuan;
Xiao, Jiaqi;
Li, Changwei;
Chen, Zhe;
Cao, Peng

Publication type:

Article

Ex vivo testing of biomaterials for intervertebral disc repair using organ culture bioreactors.

Published in:

Chemical Industry / Hemijska Industrija, 2024, v. 78, p. 6

By:

Grad, Sibylle

Publication type:

Article

The Factors Associated With the Successful Outcomes of Percutaneous Disc Decompression in Patients With Lumbar Herniated Nucleus Pulposus.

Published in:

Annals of Rehabilitation Medicine, 2015, v. 39, n. 5, p. 735, doi. 10.5535/arm.2015.39.5.735

By:

Sang Heon Lee;
Yong Jin Jeong;
Nack Hwan Kim;
Hyeun Jun Park;
Hyun-Joon Yoo;
Soo Yung Jo

Publication type:

Article

Grape seed extract inhibits nucleus pulposus cell apoptosis and attenuates annular puncture induced intervertebral disc degeneration in rabbit model.

Published in:

Anatomy & Cell Biology, 2020, v. 53, n. 3, p. 313, doi. 10.5115/acb.20.047

By:

B., Ogunlade;
O. P., Fidelis;
S. A., Adelakun;
O. A., Adedotun

Publication type:

Article

Induced pluripotent stem cell-derived mesenchymal stem cells deliver exogenous miR-105-5p via small extracellular vesicles to rejuvenate senescent nucleus pulposus cells and attenuate intervertebral disc degeneration.

Published in:

Stem Cell Research & Therapy, 2021, v. 12, n. 1, p. 1, doi. 10.1186/s13287-021-02362-1

By:

Sun, Yongjin;
Zhang, Wenzhi;
Li, Xu

Publication type:

Article

Bleomycin induces fibrotic transformation of bone marrow stromal cells to treat height loss of intervertebral disc through the TGFβR1/Smad2/3 pathway.

Published in:

Stem Cell Research & Therapy, 2021, v. 12, n. 1, p. 1, doi. 10.1186/s13287-020-02093-9

By:

Yang, Xiao;
Chen, Zhiqian;
Chen, Chen;
Han, Chen;
Zhou, Yifan;
Li, Xunlin;
Tian, Haijun;
Cheng, Xiaofei;
Zhang, Kai;
Qin, An;
Zhou, Tangjun;
Zhao, Jie

Publication type:

Article

A MODIFIED FINITE ELEMENT MODEL OF A POROVISCOELASTIC INTERVERTEBRAL DISC.

Published in:

Biomedical Engineering: Applications, Basis & Communications, 2022, v. 34, n. 6, p. 1, doi. 10.4015/S1016237222500387

By:

Veisari, Samira Fazeli;
Haghpanahi, Mohammad;
Saberi, Hooshang

Publication type:

Article

Disc regeneration by injectable fucoidan-methacrylated dextran hydrogels through mechanical transduction and macrophage immunomodulation.

Published in:

Journal of Tissue Engineering, 2023, p. 1, doi. 10.1177/20417314231180050

By:

Li, Weifeng;
Zhou, Pinghui;
Yan, Bomin;
Qi, Meiyao;
Chen, Yedan;
Shang, Lijun;
Guan, Jianzhong;
Zhang, Li;
Mao, Yingji

Publication type:

Article

microRNA-129-5p shuttled by mesenchymal stem cell-derived extracellular vesicles alleviates intervertebral disc degeneration via blockade of LRG1-mediated p38 MAPK activation.

Published in:

Journal of Tissue Engineering, 2021, v. 12, p. 1, doi. 10.1177/20417314211021679

By:

Cui, Shaoqian;
Zhang, Lei

Publication type:

Article

Development of a library of laminin-mimetic peptide hydrogels for control of nucleus pulposus cell behaviors.

Published in:

Journal of Tissue Engineering, 2021, v. 12, p. 1, doi. 10.1177/20417314211021220

By:

Speer, Julie E;
Barcellona, Marcos N;
Lu, Michael Y;
Zha, Zizhen;
Jing, Liufang;
Gupta, Munish C;
Buchowski, Jacob M;
Kelly, Michael P;
Setton, Lori A

Publication type:

Article

microRNA-129-5p shuttled by mesenchymal stem cell-derived extracellular vesicles alleviates intervertebral disc degeneration via blockade of LRG1-mediated p38 MAPK activation.

Published in:

Journal of Tissue Engineering, 2021, p. 1, doi. 10.1177/20417314211021679

By:

Cui, Shaoqian;
Zhang, Lei

Publication type:

Article

Development of a library of laminin-mimetic peptide hydrogels for control of nucleus pulposus cell behaviors.

Published in:

Journal of Tissue Engineering, 2021, p. 1, doi. 10.1177/20417314211021220

By:

Speer, Julie E;
Barcellona, Marcos N;
Lu, Michael Y;
Zha, Zizhen;
Jing, Liufang;
Gupta, Munish C;
Buchowski, Jacob M;
Kelly, Michael P;
Setton, Lori A

Publication type:

Article

Full-endoscopic interlaminar removal of chronic lumbar epidural hematoma after spinal manipulation.

Published in:

2014

By:

Yen-Po Cheng;
Kwo-Whei Lee;
Ping-Yi Lin;
Abel Po-Hao Huang;
Chun-Yuan Cheng;
Hsin-I Ma;
Chien-Min Chen;
Dueng-Yuan Hueng

Publication type:

Case Study

Evaluation of the Effectiveness of Cervical One-Hole Split Endoscopic Keyhole Surgery for Cervical Radiculopathy.

Published in:

Journal of Pain Research, 2024, v. 17, p. 3093, doi. 10.2147/JPR.S451943

By:

Feng, Yunze;
Zhang, Wencan;
Li, Kunpeng;
Lin, Xiangyu;
Liu, Chen;
Wang, Chongyi;
Hu, Bingtao;
Wang, Kaibin;
Xu, Wanlong;
Si, Haipeng

Publication type:

Article

Mast Cells and Their Related Gene HK-1 are Closely Associated with Discogenic Low Back Pain: A Bioinformatics and Clinical Sample Study.

Published in:

Journal of Pain Research, 2024, v. 17, p. 1401, doi. 10.2147/JPR.S454785

By:

He, Shouyu;
Liu, Xiaowen;
Luo, Shenchang;
Li, Haidong;
Min, Jikang;
Shi, Qian

Publication type:

Article

Percutaneous Endoscopic Transforaminal Discectomy for the Treatment of Lumbar Disc Herniation with Different Migration Levels: A Retrospective Study.

Published in:

Journal of Pain Research, 2024, v. 17, p. 367, doi. 10.2147/JPR.S437968

By:

Sun, Jiewei;
Yu, Xiaojun;
Feng, Kan;
Zheng, Wujun;
Lu, Yong;
Bao, Bin

Publication type:

Article

Upper Lumbar Intradural Disc Herniation: A Rare Case Report and Etiologic Analysis.

Published in:

Journal of Pain Research, 2021, v. 14, p. 1475, doi. 10.2147/JPR.S297304

By:

Chen, Jia;
Ni, Hai-Jian;
Xue, Fei;
Fan, Yun-Shan;
Li, Xi-Fan;
Chen, Xian-Zhen;
He, Shi-Sheng

Publication type:

Article

Incidence of Adrenal Insufficiency and Cushing's Syndrome After Long-Term Epidural Steroid Injections Over Six Months or Longer: A Preliminary Study.

Published in:

Journal of Pain Research, 2020, v. 13, p. 1505, doi. 10.2147/JPR.S252278

By:

Park, JungHyun;
Kwak, Jueun;
Chung, Sukyung;
Hong, Hyo Ju;
Chon, Jin Young;
Moon, Ho Sik

Publication type:

Article

Characterization of novel lnc RNAs in the spinal cord of rats with lumbar disc herniation.

Published in:

Journal of Pain Research, 2019, v. 12, p. 501, doi. 10.2147/JPR.S164604

By:

Wang, Qianliang;
Ai, Hongzhen;
Liu, Jinglin;
Xu, Min;
Zhou, Zhuang;
Qian, Chen;
Xie, Ye;
Yan, Jun

Publication type:

Article

Increased local expressions of CX3CL1 and CCL2 are related to clinical severity in lumbar disk herniation patients with sciatic pain.

Published in:

Journal of Pain Research, 2017, v. 10, p. 157, doi. 10.2147/JPR.S125914

By:

Zhen-Yu Peng;
Rui Chen;
Zuo-Zhong Fang;
Bin Chen;
Zhi-Hua Wang;
Xi-Yang Wang

Publication type:

Article

ANTIOXIDATIVE BEHAVIOR OF α2-MACROGLOBULIN IN INTERVERTEBRAL DISC DEGENERATION.

Published in:

Journal of Medical Biochemistry, 2023, v. 42, n. 2, p. 206, doi. 10.5937/jomb0-39557

By:

Yuhong Chen;
Huaixiang Wei;
Feng Xu

Publication type:

Article

Effects of Changes in Osmolarity on the Biological Activity of Human Normal Nucleus Pulposus Mesenchymal Stem Cells.

Published in:

Stem Cells International, 2022, p. 1, doi. 10.1155/2022/1121064

By:

Zhang, Hua;
Li, Wei;
Wu, YaoHong;
Zhang, Shengquan;
Li, Jie;
Han, Letian;
Chen, Haoyu;
Wang, Ziyu;
Shen, Cailiang;
Zhang, Yinshun;
Tao, Hui

Publication type:

Article

Aloin Regulates Matrix Metabolism and Apoptosis in Human Nucleus Pulposus Cells via the TAK1/NF-κB/NLRP3 Signaling Pathway.

Published in:

Stem Cells International, 2022, p. 1, doi. 10.1155/2022/5865011

By:

Chen, Taiqiu;
Li, Pengfei;
Qiu, Jincheng;
Hu, Wenjun;
Li, Shaoguang;
Shi, Huihong;
Qiu, Xianjian;
Huang, Dongsheng;
Gao, Wenjie;
Liang, Anjing

Publication type:

Article

Nucleus Pulposus Cell Conditioned Medium Promotes Mesenchymal Stem Cell Differentiation into Nucleus Pulposus-Like Cells under Hypoxic Conditions.

Published in:

Stem Cells International, 2020, p. 1, doi. 10.1155/2020/8882549

By:

Sinkemani, Arjun;
Wang, Feng;
Xie, Zhiyang;
Chen, Lu;
Zhang, Cong;
Wu, Xiaotao

Publication type:

Article

Senescent response in inner annulus fibrosus cells in response to TNFα, H<sub>2</sub>O<sub>2</sub>, and TNFα-induced nucleus pulposus senescent secretome.

Published in:

PLoS ONE, 2024, v. 19, n. 1, p. 1, doi. 10.1371/journal.pone.0280101

By:

Montgomery-Song, Aaryn;
Ashraf, Sajjad;
Santerre, Paul;
Kandel, Rita

Publication type:

Article

Clinical characteristics associated with cervical hydrated nucleus pulposus extrusion in dogs.

Published in:

Journal of Veterinary Internal Medicine, 2025, v. 39, n. 1, p. 1, doi. 10.1111/jvim.17284

By:

Lin, Megan;
Hong, Christopher X.;
Rishniw, Mark;
Davies, Emma S.;
Wood, Jonathan H.

Publication type:

Article