Works matching DE "NUCLEOTIDE exchange factors"

Results: 160

Screening Enamine Fragments Library in the Quest for Novel SOS2 Inhibitors: Pharmacophore Modelling, Molecular Docking, MMGBSA Calculations, and MD Simulation.

Published in:

Journal of Pharmacy & Bioallied Sciences, 2025, v. 17, p. S1894, doi. 10.4103/jpbs.jpbs_534_25

By:

Alzain, Abdulrahim A.;
Almogaddam, Mohammed A.;
Makki, Alaa A.;
Edris, Alaa;
Mohamed, Hagar M.;
Ehaimir, Sitelbanat Y.;
Mohamed, Shaimaa G. A.;
Taher Felemban, Sarah Ameen;
Hammad Alshammari, Wedad Hamad;
Mohamed, Gamal A.;
Ibrahim, Sabrin R. M.

Publication type:

Article

Optogenetic control of a GEF of RhoA uncovers a signaling switch from retraction to protrusion.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.93180

By:

de Seze, Jean;
Bongaerts, Maud;
Boulevard, Benoit;
Coppey, Mathieu

Publication type:

Article

The Importance of Mg2+‐Free State in Nucleotide Exchange of Oncogenic K‐Ras Mutants.

Published in:

Chemistry - A European Journal, 2022, v. 28, n. 59, p. 1, doi. 10.1002/chem.202201449

By:

Pálfy, Gyula;
Menyhárd, Dóra K.;
Ákontz‐Kiss, Hanna;
Vida, István;
Batta, Gyula;
Tőke, Orsolya;
Perczel, András

Publication type:

Article

DOCK8 deficiency: cellular and molecular mechanisms.

Published in:

Turkish Journal of Immunology, 2016, v. 4, p. 14

By:

Chatila, Talal

Publication type:

Article

Insights into the Localization and Function of the Membrane Trafficking Regulator GNOM ARF-GEF at the Golgi Apparatus in Arabidopsis.

Published in:

Plant Cell, 2014, v. 26, n. 7, p. 3062, doi. 10.1105/tpc.114.125880

By:

Naramoto, Satoshi;
Otegui, Marisa S.;
Kutsuna, Natsumaro;
Rycke, Riet de;
Dainobu, Tomoko;
Karampelias, Michael;
Fujimoto, Masaru;
Feraru, Elena;
Miki, Daisuke;
Fukuda, Hiroo;
Nakano, Akihiko;
Friml, Jiří

Publication type:

Article

Physcomitrella Reveals a Key Role for Stromal Hsp70 Chaperones in Chloroplast Protein Import.

Published in:

Plant Cell, 2010, v. 22, n. 1, p. 1, doi. 10.1105/tpc.109.220110

By:

Eckardt, Nancy A.

Publication type:

Article

Stromal Heat Shock Protein 70 System Functions in Protein Import into Chloroplasts in the Moss Physcomitrella patens.

Published in:

Plant Cell, 2010, v. 22, n. 1, p. 205, doi. 10.1105/tpc.109.071464

By:

Shi, Lan-Xin;
Theg, Steven M.

Publication type:

Article

ARHGEF28 gene exon 6/intron 6 junction mutations in Chinese amyotrophic lateral sclerosis cohort.

Published in:

Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration, 2014, v. 15, n. 3/4, p. 309, doi. 10.3109/21678421.2014.896926

By:

Ma, Yan;
Tang, Lu;
Chen, Lu;
Zhang, Bin;
Deng, Pan;
Wang, Jingran;
Yang, Yi;
Liu, Rong;
Yang, Yan;
Ye, Shan;
Liu, Xiaolu;
Zhang, Huagang;
Fan, Dongsheng

Publication type:

Article

Rho guanine nucleotide exchange factors: regulators of Rho GTPase activity in development and disease.

Published in:

Oncogene, 2014, v. 33, n. 31, p. 4021, doi. 10.1038/onc.2013.362

By:

Cook, D R;
Rossman, K L;
Der, C J

Publication type:

Article

Overexpression of OsCYP19-4 increases tolerance to cold stress and enhances grain yield in rice (Oryza sativa).

Published in:

Journal of Experimental Botany, 2016, v. 67, n. 1, p. 69, doi. 10.1093/jxb/erv421

By:

Dae Hwa Yoon;
Sang Sook Lee;
Hyun Ji Park;
Jae Il Lyu;
Won Seog Chong;
Jang Ryol Liu;
Beom-Gi Kim;
Jun Cheul Ahn;
Hye Sun Cho

Publication type:

Article

Detour Ahead: Incretin Hormone Signaling Alters Its Intracellular Path as β-Cell Failure Progresses During Diabetes.

Published in:

Frontiers in Endocrinology, 2021, v. 11, p. N.PAG, doi. 10.3389/fendo.2021.665345

By:

Hussain, Mehboob A.;
Laimon-Thomson, Erinn;
Mustafa, Syed M.;
Deck, Alexander;
Song, Banya

Publication type:

Article

Involvement of cAMP-guanine nucleotide exchange factor II in hippocampal long-term depression and behavioral flexibility.

Published in:

Molecular Brain, 2015, v. 8, n. 1, p. 1, doi. 10.1186/s13041-015-0130-1

By:

Kyungmin Lee;
Yuki Kobayashi;
Hyunhyo Seo;
Ji-Hye Kwak;
Akira Masuda;
Chae-Seok Lim;
Hye-Ryeon Lee;
SukJae Joshua Kang;
Pojeong Park;
Su-Eon Sim;
Naomi Kogo;
Hiroaki Kawasaki;
Bong-Kiun Kaang;
Shigeyoshi Itohara

Publication type:

Article

A role for Gic1 and Gic2 in Cdc42 polarization at elevated temperature.

Published in:

PLoS ONE, 2018, v. 13, n. 12, p. 1, doi. 10.1371/journal.pone.0200863

By:

Daniels, Christine N.;
Zyla, Trevin R.;
Lew, Daniel J.

Publication type:

Article

Solo, a RhoA-targeting guanine nucleotide exchange factor, is critical for hemidesmosome formation and acinar development in epithelial cells.

Published in:

PLoS ONE, 2018, v. 13, n. 3, p. 1, doi. 10.1371/journal.pone.0195124

By:

Fujiwara, Sachiko;
Matsui, Tsubasa S.;
Ohashi, Kazumasa;
Deguchi, Shinji;
Mizuno, Kensaku

Publication type:

Article

Multiple Chaperone DnaK–FliC Flagellin Interactions are Required for Pseudomonas aeruginosa Flagellum Assembly and Indicate a New Function for DnaK.

Published in:

Microbial Biotechnology, 2025, v. 18, n. 2, p. 1, doi. 10.1111/1751-7915.70096

By:

Molinari, Gabriella;
Ribeiro, Sara S.;
Müller, Katrin;
Mayer, Benjamin E.;
Rohde, Manfred;
Arce‐Rodriguez, Alejandro;
Vargas‐Guerrero, Juan José;
Avetisyan, Albert;
Wissing, Josef;
Tegge, Werner;
Jänsch, Lothar;
Brönstrup, Mark;
Danchin, Antoine;
Jahn, Martina;
Timmis, Kenneth N.;
Ebbinghaus, Simon;
Jahn, Dieter;
Borrero‐de Acuña, José Manuel

Publication type:

Article

The Invasive Capacity of HPV Transformed Cells Requires the hDlg-Dependent Enhancement of SGEF/RhoG Activity.

Published in:

PLoS Pathogens, 2012, v. 8, n. 2, p. 1, doi. 10.1371/journal.ppat.1002543

By:

Subbaiah, Vanitha Krishna;
Massimi, Paola;
Boon, Siaw Shi;
Myers, Michael P.;
Sharek, Lisa;
Garcia-Mata, Rafael;
Banks, Lawrence

Publication type:

Article

Development of a Nucleotide Exchange Inhibitor That Impairs Ras Oncogenic Signaling.

Published in:

Chemistry - A European Journal, 2017, v. 23, n. 7, p. 1676, doi. 10.1002/chem.201604905

By:

Marín‐Ramos, Nagore I.;
Piñar, Carmen;
Vázquez‐Villa, Henar;
Martín‐Fontecha, Mar;
González, Ángel;
Canales, Ángeles;
Algar, Sergio;
Mayo, Paloma P.;
Jiménez‐Barbero, Jesús;
Gajate, Consuelo;
Mollinedo, Faustino;
Pardo, Leonardo;
Ortega‐Gutiérrez, Silvia;
Viso, Alma;
López‐Rodríguez, María L.

Publication type:

Article

Grb2 interacts with SGEF and antagonizes the ability of SGEF to enhance EGF-induced ERK1/2 activation.

Published in:

Molecular & Cellular Biochemistry, 2014, v. 389, n. 1/2, p. 239, doi. 10.1007/s11010-013-1945-7

By:

Wang, Hongtao;
Li, Shanhu;
Li, Hailiang;
Wang, Peng;
Huang, Fang;
Zhao, Yali;
Yu, Lan;
Luo, Guolan;
Zhang, Xiaoqing;
Wang, Jian;
Zhou, Jianguang

Publication type:

Article

Crucial HSP70 co-chaperone complex unlocks metazoan protein disaggregation.

Published in:

Nature, 2015, v. 524, n. 7564, p. 247, doi. 10.1038/nature14884

By:

Nillegoda, Nadinath B.;
Kirstein, Janine;
Szlachcic, Anna;
Berynskyy, Mykhaylo;
Stank, Antonia;
Stengel, Florian;
Arnsburg, Kristin;
Gao, Xuechao;
Scior, Annika;
Aebersold, Ruedi;
Guilbride, D. Lys;
Wade, Rebecca C.;
Morimoto, Richard I.;
Mayer, Matthias P.;
Bukau, Bernd

Publication type:

Article

Cold adaptation in the environmental bacterium Shewanella oneidensis is controlled by a J-domain co-chaperone protein network.

Published in:

Communications Biology, 2019, v. 2, n. 1, p. N.PAG, doi. 10.1038/s42003-019-0567-3

By:

Maillot, Nathanael Jean;
Honoré, Flora Ambre;
Byrne, Deborah;
Méjean, Vincent;
Genest, Olivier

Publication type:

Article

Identification of a new HLA-DQB106 allele, HLA-DQB106:210, by monoallelic Sanger sequencing.

Published in:

HLA: Immune Response Genetics, 2017, v. 90, n. 2, p. 132, doi. 10.1111/tan.13043

By:

Kuzmich, E.;
Nasredinova, A.;
Alyanskiy, A.;
Afanasyev, B.

Publication type:

Article

Detection of a new HLA-B44 allele, HLA-B44:02:45, by monoallelic Sanger sequencing.

Published in:

HLA: Immune Response Genetics, 2017, v. 90, n. 2, p. 124, doi. 10.1111/tan.13048

By:

Kuzmich, E.;
Makarenko, O.;
Alyanskiy, A.;
Afanasyev, B.

Publication type:

Article

Description of a new HLA-A02 allele, A02:658, in a Russian individual.

Published in:

HLA: Immune Response Genetics, 2017, v. 89, n. 4, p. 235, doi. 10.1111/tan.12995

By:

Loginova, M.;
Jankevich, T.;
Goltsov, A.;
Altukhova, O.;
Trofimov, D.

Publication type:

Article

HLA-B15:388, a novel variant of HLA-B15, discovered in a Taiwanese individual.

Published in:

HLA: Immune Response Genetics, 2016, v. 88, n. 4, p. 204, doi. 10.1111/tan.12877

By:

Yang, K. L.;
Lin, P. Y.

Publication type:

Article

A novel HLA-B allele, HLA-B*40:01:47.

Published in:

HLA: Immune Response Genetics, 2016, v. 87, n. 6, p. 461, doi. 10.1111/tan.12806

By:

Zhu, Y.‐Y.;
Qiang, W.;
Shen, G.;
Zou, J.;
Jiang, Y.‐Z.

Publication type:

Article

How endothelial junctions get deep-Syx'd.

Published in:

Journal of Cell Biology, 2012, v. 199, n. 7, p. 1018, doi. 10.1083/jcb.1997iti3

By:

Short, Ben

Publication type:

Article

eIF2B conformation and assembly state regulate the integrated stress response.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.65703

By:

Schoof, Michael;
Boone, Morgane;
Lan Wang;
Lawrence, Rosalie;
Frost, Adam;
Walter, Peter

Publication type:

Article

Lysine Acetylation Reshapes the Downstream Signaling Landscape of Vav1 in Lymphocytes.

Published in:

Cells (2073-4409), 2020, v. 9, n. 3, p. 609, doi. 10.3390/cells9030609

By:

Rodríguez-Fdez, Sonia;
Fernández-Nevado, Lucía;
Lorenzo-Martín, L. Francisco;
Bustelo, Xosé R.

Publication type:

Article

The Vav GEF Family: An Evolutionary and Functional Perspective.

Published in:

Cells (2073-4409), 2019, v. 8, n. 5, p. 465, doi. 10.3390/cells8050465

By:

Rodríguez-Fdez, Sonia;
Bustelo, Xosé R.

Publication type:

Article

The Intermolecular Interaction of Ephexin4 Leads to Autoinhibition by Impeding Binding of RhoG.

Published in:

Cells (2073-4409), 2018, v. 7, n. 11, p. 211, doi. 10.3390/cells7110211

By:

Kim, Kwanhyeong;
Lee, Juyeon;
Moon, Hyunji;
Lee, Sang-Ah;
Kim, Deokhwan;
Yang, Susumin;
Lee, Dae-Hee;
Lee, Gwangrog;
Park, Daeho

Publication type:

Article

Review: Protein misfolding diseases – the rare case of Marinesco‐Sjögren syndrome.

Published in:

Neuropathology & Applied Neurobiology, 2020, v. 46, n. 4, p. 323, doi. 10.1111/nan.12588

By:

Chiesa, R.;
Sallese, M.

Publication type:

Article

Disease-associated mutations within the yeast DNAJB6 homolog Sis1 slow conformer-specific substrate processing and can be corrected by the modulation of nucleotide exchange factors.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-32318-9

By:

Bhadra, Ankan K.;
Rau, Michael J.;
Daw, Jil A.;
Fitzpatrick, James A. J.;
Weihl, Conrad C.;
True, Heather L.

Publication type:

Article

Viral evasion of the integrated stress response through antagonism of eIF2-P binding to eIF2B.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26164-4

By:

Schoof, Michael;
Wang, Lan;
Cogan, J. Zachery;
Lawrence, Rosalie E.;
Boone, Morgane;
Wuerth, Jennifer Deborah;
Frost, Adam;
Walter, Peter

Publication type:

Article

Targeting nucleotide exchange to inhibit constitutively active G protein α subunits in cancer cells.

Published in:

Science Signaling, 2018, v. 11, n. 546, p. 1, doi. 10.1126/scisignal.aao6852

By:

Onken, Michael D.;
Makepeace, Carol M.;
Kaltenbronn, Kevin M.;
Kanai, Stanley M.;
Todd, Tyson D.;
Wang, Shiqi;
Broekelmann, Thomas J.;
Rao, Prabakar Kumar;
Cooper, John A.;
Blumer, Kendall J.

Publication type:

Article

Convergence of Wnt, growth factor, and heterotrimeric G protein signals on the guanine nucleotide exchange factor Daple.

Published in:

Science Signaling, 2018, v. 11, n. 519, p. 1, doi. 10.1126/scisignal.aao4220

By:

Aznar, Nicolas;
Ear, Jason;
Dunkel, Ying;
Sun, Nina;
Satterfield, Kendall;
He, Fang;
Kalogriopoulos, Nicholas A.;
Lopez-Sanchez, Inmaculada;
Ghassemian, Majid;
Sahoo, Debashis;
Kufareva, Irina;
Ghosh, Pradipta

Publication type:

Article

Plant Translation Elongation Factor 1Bβ Facilitates Potato Virus X (PVX) Infection and Interacts with PVX Triple Gene Block Protein 1.

Published in:

PLoS ONE, 2015, v. 10, n. 5, p. 1, doi. 10.1371/journal.pone.0128014

By:

Hwang, JeeNa;
Lee, Seonhee;
Lee, Joung-Ho;
Kang, Won-Hee;
Kang, Jin-Ho;
Kang, Min-Young;
Oh, Chang-Sik;
Kang, Byoung-Cheorl

Publication type:

Article

Hsp70 Cochaperones HspBP1 and BAG-1M Differentially Regulate Steroid Hormone Receptor Function.

Published in:

PLoS ONE, 2014, v. 9, n. 1, p. 1, doi. 10.1371/journal.pone.0085415

By:

Knapp, Regina T.;
Wong, Michael J. H.;
Kollmannsberger, Lorenz K.;
Gassen, Nils C.;
Kretzschmar, Anja;
Zschocke, Jürgen;
Hafner, Kathrin;
Young, Jason C.;
Rein, Theo

Publication type:

Article

AKAP13 Rho-GEF and PKD-Binding Domain Deficient Mice Develop Normally but Have an Abnormal Response to β-Adrenergic-Induced Cardiac Hypertrophy.

Published in:

PLoS ONE, 2013, v. 8, n. 4, p. 1, doi. 10.1371/journal.pone.0062705

By:

Spindler, Matthew J.;
Burmeister, Brian T.;
Huang, Yu;
Hsiao, Edward C.;
Salomonis, Nathan;
Scott, Mark J.;
Srivastava, Deepak;
Carnegie, Graeme K.;
Conklin, Bruce R.

Publication type:

Article

A Core Filamentation Response Network in Candida albicans Is Restricted to Eight Genes.

Published in:

PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0058613

By:

Martin, Ronny;
Albrecht-Eckardt, Daniela;
Brunke, Sascha;
Hube, Bernhard;
Hünniger, Kerstin;
Kurzai, Oliver

Publication type:

Article

EspO1-2 Regulates EspM2-Mediated RhoA Activity to Stabilize Formation of Focal Adhesions in Enterohemorrhagic Escherichia coli-Infected Host Cells.

Published in:

PLoS ONE, 2013, v. 8, n. 2, p. 1, doi. 10.1371/journal.pone.0055960

By:

Morita-Ishihara, Tomoko;
Miura, Masashi;
Iyoda, Sunao;
Izumiya, Hidemasa;
Watanabe, Haruo;
Ohnishi, Makoto;
Terajima, Jun

Publication type:

Article

Fission Yeast Nod1 Is a Component of Cortical Nodes Involved in Cell Size Control and Division Site Placement.

Published in:

PLoS ONE, 2013, v. 8, n. 1, p. 1, doi. 10.1371/journal.pone.0054142

By:

Jourdain, Isabelle;
Brzezińska, Elspeth A.;
Toda, Takashi

Publication type:

Article

P-Rex1 Cooperates with PDGFRβ; to Drive Cellular Migration in 3D Microenvironments.

Published in:

PLoS ONE, 2013, v. 8, n. 1, p. 1, doi. 10.1371/journal.pone.0053982

By:

Campbell, Andrew D.;
Lawn, Samuel;
McGarry, Lynn C.;
Welch, Heidi C.;
Ozanne, Bradford W.;
Norman, Jim C.

Publication type:

Article

The Guanine Nucleotide Exchange Factor Kalirin-7 Is a Novel Synphilin-1 Interacting Protein and Modifies Synphilin-1 Aggregate Transport and Formation.

Published in:

PLoS ONE, 2012, v. 7, n. 12, p. 1, doi. 10.1371/journal.pone.0051999

By:

Tsai, Yu-Chun;
Riess, Olaf;
Soehn, Anne S.;
Nguyen, Huu Phuc

Publication type:

Article

The Adaptor Molecule Nck Localizes the WAVE Complex to Promote Actin Polymerization during CEACAM3- Mediated Phagocytosis of Bacteria.

Published in:

PLoS ONE, 2012, v. 7, n. 3, p. 1, doi. 10.1371/journal.pone.0032808

By:

Pils, Stefan;
Kopp, Kathrin;
Peterson, Lisa;
Tascón, Julia Delgado;
Nyffenegger-Jann, Naja J.;
Hauck, Christof R.

Publication type:

Article

The Nucleotide Exchange Factor Ric-8A Is a Chaperone for the Conformationally Dynamic Nucleotide-Free State of Gαi1.

Published in:

PLoS ONE, 2011, v. 6, n. 8, p. 1, doi. 10.1371/journal.pone.0023197

By:

Thomas, Celestine J.;
Briknarová, Klá ra;
Hilmer, Jonathan K.;
Movahed, Navid;
Bothner, Brian;
Sumida, John P.;
Tall, Gregory G.;
Sprang, Stephen R.

Publication type:

Article

The higher level of complexity of K-Ras4B activation at the membrane.

Published in:

FASEB Journal, 2016, v. 30, n. 4, p. 1643, doi. 10.1096/fj.15-279091

By:

Hyunbum Jang;
Banerjee, Avik;
Chavan, Tanmay S.;
Shaoyong Lu;
Jian Zhang;
Gaponenko, Vadim;
Nussinov, Ruth

Publication type:

Article

Functional adaptation of the switch-2 nucleotide sensor enables rapid processive translocation by myosin-5.

Published in:

FASEB Journal, 2010, v. 24, n. 11, p. 4480, doi. 10.1096/fj.10-163998

By:

Nagy, Nikolett T.;
Sakamoto, Takeshi;
Takács, Balázs;
Gyimesi, Máté;
Hazai, Eszter;
Bikádi, Zsolt;
Sellers, James R.;
Kovács, Mihály

Publication type:

Article

Marinesco-Sjögren Syndrome: A Report of two Cases.

Published in:

2024

By:

Malik, Nazish;
Arif, Mohd;
Bhatnagar, Shirish

Publication type:

Letter

Nascency of Physiopathological Activation by The Effect of Genomic Single Nucleotide Exchange Factor in The PNPLA3 rs738409 Genotype of Patients with Hepatocellular Carcinoma.

Published in:

Celal Bayar University Journal of Science, 2024, v. 20, n. 4, p. 20, doi. 10.18466/cbayarfbe.1437557

By:

Delik, Anıl;
Ülger, Yakup

Publication type:

Article

Expression of DOCK9 and DOCK11 Analyzed with Commercial Antibodies: Focus on Regulation of Mutually Exclusive First Exon Isoforms.

Published in:

Antibodies (2073-4468), 2020, v. 9, n. 3, p. 27, doi. 10.3390/antib9030027

By:

Parrado, Antonio

Publication type:

Article