Works matching DE "NUCLEASE genetics"

Results: 70

The Rad1-Rad10 nuclease promotes chromosome translocations between dispersed repeats.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 9, p. 964, doi. 10.1038/nsmb.2359

By:

Mazón, Gerard;
Lam, Alicia F;
Ho, Chu Kwen;
Kupiec, Martin;
Symington, Lorraine S

Publication type:

Article

The molecular architecture of human Dicer.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 4, p. 436, doi. 10.1038/nsmb.2268

By:

Lau, Pick-Wei;
Guiley, Keelan Z;
De, Nabanita;
Potter, Clinton S;
Carragher, Bridget;
MacRae, Ian J

Publication type:

Article

Application of ZFN for Site Directed Mutagenesis of Rice <italic>SSIVa</italic> Gene.

Published in:

Biotechnology & Bioprocess Engineering, 2018, v. 23, n. 1, p. 108, doi. 10.1007/s12257-017-0420-9

By:

Jung, Yu-Jin;
Nogoy, Franz Marielle;
Lee, Sang-Kyu;
Cho, Yong-Gu;
Kang, Kwon-Kyoo

Publication type:

Article

Distinct features of lamin A-interacting chromatin domains mapped by ChIP-sequencing from sonicated or micrococcal nuclease-digested chromatin.

Published in:

Nucleus (1949-1034), 2015, v. 6, n. 1, p. 30, doi. 10.4161/19491034.2014.990855

By:

Lund, Eivind G;
Duband-Goulet, Isabelle;
Oldenburg, Anja;
Buendia, Brigitte;
Collas, Philippe

Publication type:

Article

High-Efficiency Targeted Editing of Large Viral Genomes by RNA-Guided Nucleases.

Published in:

PLoS Pathogens, 2014, v. 10, n. 5, p. 1, doi. 10.1371/journal.ppat.1004090

By:

Bi, Yanwei;
Sun, Le;
Gao, Dandan;
Ding, Chen;
Li, Zhihua;
Li, Yadong;
Cun, Wei;
Li, Qihan

Publication type:

Article

CRISPR-Cas immunity in prokaryotes.

Published in:

Nature, 2015, v. 526, n. 7571, p. 55, doi. 10.1038/nature15386

By:

Marraffini, Luciano A.

Publication type:

Article

Cytotoxic Effects during Knock Out of Multiple Porcine Endogenous Retrovirus (PERV) Sequences in the Pig Genome by Zinc Finger Nucleases (ZFN).

Published in:

PLoS ONE, 2015, v. 10, n. 4, p. 1, doi. 10.1371/journal.pone.0122059

By:

Semaan, Marwan;
Ivanusic, Daniel;
Denner, Joachim

Publication type:

Article

Evaluation of sgRNA Target Sites for CRISPR-Mediated Repression of TP53.

Published in:

PLoS ONE, 2014, v. 9, n. 11, p. 1, doi. 10.1371/journal.pone.0113232

By:

Lawhorn, Ingrid E. B.;
Ferreira, Joshua P.;
Wang, Clifford L.

Publication type:

Article

Bacterial Delivery of TALEN Proteins for Human Genome Editing.

Published in:

PLoS ONE, 2014, v. 9, n. 3, p. 1, doi. 10.1371/journal.pone.0091547

By:

Jia, Jingyue;
Jin, Yongxin;
Bian, Ting;
Wu, Donghai;
Yang, Lijun;
Terada, Naohiro;
Wu, Weihui;
Jin, Shouguang

Publication type:

Article

A Modified TALEN-Based Strategy for Rapidly and Efficiently Generating Knockout Mice for Kidney Development Studies.

Published in:

PLoS ONE, 2014, v. 9, n. 1, p. 1, doi. 10.1371/journal.pone.0084893

By:

Liu, Yunhong;
Lv, Xiaoyan;
Tan, Ruizhi;
Liu, Tianming;
Chen, Tielin;
Li, Mi;
Liu, Yuhang;
Nie, Fang;
Wang, Xiaoyan;
Zhou, Puhui;
Chen, Mianzhi;
Zhou, Qin

Publication type:

Article

Rapid Assembly of Customized TALENs into Multiple Delivery Systems.

Published in:

PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0080281

By:

Zhang, Zhengxing;
Zhang, Siliang;
Huang, Xin;
Orwig, Kyle E.;
Sheng, Yi

Publication type:

Article

The Design and <i>In Vivo</i> Evaluation of Engineered I-OnuI-Based Enzymes for HEG Gene Drive.

Published in:

PLoS ONE, 2013, v. 8, n. 9, p. 1, doi. 10.1371/journal.pone.0074254

By:

Chan, Yuk-Sang;
Takeuchi, Ryo;
Jarjour, Jordan;
Huen, David S.;
Stoddard, Barry L.;
Russell, Steven

Publication type:

Article

Improved Somatic Mutagenesis in Zebrafish Using Transcription Activator-Like Effector Nucleases (TALENs).

Published in:

PLoS ONE, 2012, v. 7, n. 5, p. 1, doi. 10.1371/journal.pone.0037877

By:

Moore, Finola E.;
Reyon, Deepak;
Sander, Jeffry D.;
Martinez, Sarah A.;
Blackburn, Jessica S.;
Khayter, Cyd;
Ramirez, Cherie L.;
Joung, J. Keith;
Langenau, David M.

Publication type:

Article

A triple-helix forming oligonucleotide targeting genomic DNA fails to induce mutation.

Published in:

Mutagenesis, 2012, v. 27, n. 6, p. 713, doi. 10.1093/mutage/ges037

By:

Reshat, Reshat;
Priestley, Catherine C.;
Gooderham, Nigel J.

Publication type:

Article

Improving Fab' fragment retention in an autonucleolytic Escherichia coli strain by swapping periplasmic nuclease translocation signal from OmpA to DsbA.

Published in:

Biotechnology Letters, 2017, v. 39, n. 12, p. 1865, doi. 10.1007/s10529-017-2425-z

By:

Schofield, Desmond;
Sirka, Ernestas;
Keshavarz-Moore, Eli;
Ward, John;
Nesbeth, Darren

Publication type:

Article

Genome editing in plants via designed zinc finger nucleases.

Published in:

In Vitro Cellular & Developmental Biology Plant, 2015, v. 51, n. 1, p. 1, doi. 10.1007/s11627-015-9663-3

By:

Petolino, Joseph

Publication type:

Article

RecBCD Enzyme "Chi Recognition" Mutants Recognize Chi Recombination Hotspots in the Right DNA Context.

Published in:

Genetics, 2016, v. 204, n. 1, p. 139, doi. 10.1534/genetics.116.191056

By:

Amundsen, Susan K.;
Sharp, Jake W.;
Smith, Gerald R.

Publication type:

Article

In Vivo Transcriptional Activation Using CRISPR/Cas9 in Drosophila.

Published in:

Genetics, 2015, v. 201, n. 2, p. 433, doi. 10.1534/genetics.115.181065

By:

Shuailiang Lin;
Ewen-Campen, Ben;
Xiaochun Ni;
Housden, Benjamin E.;
Perrimon, Norbert

Publication type:

Article

TALENs Mediate Efficient and Heritable Mutation of Endogenous Genes in the Marine Annelid Platynereis dumerilii.

Published in:

Genetics, 2014, v. 197, n. 1, p. 77, doi. 10.1534/genetics.113.161091

By:

Bannister, Stephanie;
Antonova, Olga;
Polo, Alessandra;
Lohs, Claudia;
Hallay, Natalia;
Valinciute, Agne;
Raible, Florian;
Tessmar-Raible, Kristin

Publication type:

Article

Exciting Prospects for Precise Engineering of Caenorhabditis elegans Genomes with CRISPR/Cas9.

Published in:

Genetics, 2013, v. 195, n. 3, p. 635, doi. 10.1534/genetics.113.156521

By:

Frøkjær-Jensen, Christian

Publication type:

Article

The Exonuclease Activity of the Yeast Mitochondrial DNA Polymerase γ Suppresses Mitochondrial DNA Deletions Between Short Direct Repeats in Saccharomyces cerevisiae.

Published in:

Genetics, 2013, v. 194, n. 2, p. 519, doi. 10.1534/genetics.113.150920

By:

Stumpf, Jeffrey D.;
Copeland, William C.

Publication type:

Article

Optimized tuning of TALEN specificity using non-conventional RVDs.

Published in:

Scientific Reports, 2015, p. 8150, doi. 10.1038/srep08150

By:

Juillerat, Alexandre;
Pessereau, Coline;
Dubois, Gwendoline;
Guyot, Valérie;
Maréchal, Alan;
Valton, Julien;
Daboussi, Fayza;
Poirot, Laurent;
Duclert, Aymeric;
Duchateau, Philippe

Publication type:

Article

Enhancing Targeted Genomic DNA Editing in Chicken Cells Using the CRISPR/Cas9 System.

Published in:

PLoS ONE, 2017, v. 12, n. 1, p. 1, doi. 10.1371/journal.pone.0169768

By:

Wang, Ling;
Yang, Likai;
Guo, Yijie;
Du, Weili;
Yin, Yajun;
Zhang, Tao;
Lu, Hongzhao

Publication type:

Article

FANCD2-Controlled Chromatin Access of the Fanconi-Associated Nuclease FAN1 Is Crucial for the Recovery of Stalled Replication Forks.

Published in:

Molecular & Cellular Biology, 2014, v. 34, n. 21, p. 3939, doi. 10.1128/MCB.00457-14

By:

Chaudhury, Indrajit;
Stroik, Daniel R.;
Sobeck, Alexandra

Publication type:

Article

A comprehensive overview of computational resources to aid in precision genome editing with engineered nucleases.

Published in:

Briefings in Bioinformatics, 2017, v. 18, n. 4, p. 698, doi. 10.1093/bib/bbw052

By:

Periwal, Vinita

Publication type:

Article

Rapid, precise quantification of large DNA excisions and inversions by ddPCR.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-71742-z

By:

Watry, Hannah L.;
Feliciano, Carissa M.;
Gjoni, Ketrin;
Takahashi, Gou;
Miyaoka, Yuichiro;
Conklin, Bruce R.;
Judge, Luke M.

Publication type:

Article

Genome editing through large insertion leads to the skipping of targeted exon.

Published in:

BMC Genomics, 2015, v. 16, p. 1, doi. 10.1186/s12864-015-2284-8

By:

Uddin, Borhan;
Nan-Peng Chen;
Panic, Marko;
Schiebel, Elmar

Publication type:

Article

Multiplex genomic structure variation mediated by TALEN and ssODN.

Published in:

BMC Genomics, 2014, v. 15, n. 1, p. 1, doi. 10.1186/1471-2164-15-41

By:

Sanyuan Ma;
Xiaogang Wang;
Yuanyuan Liu;
Jie Gao;
Shengling Zhang;
Run Shi;
Jiasong Chang;
Ping Zhao;
Qingyou Xia

Publication type:

Article

Role of endonuclease G in exogenous DNA stability in HeLa cells.

Published in:

Biochemistry (00062979), 2016, v. 81, n. 2, p. 163, doi. 10.1134/S0006297916020103

By:

Misic, V.;
El-Mogy, M.;
Haj-Ahmad, Y.

Publication type:

Article

In This Issue.

Published in:: Molecular Therapy, 2015, v. 23, n. 10, p. 1554, doi. 10.1038/mt.2015.159
Publication type:: Article

Clinical Scale Zinc Finger Nuclease-mediated Gene Editing of PD-1 in Tumor Infiltrating Lymphocytes for the Treatment of Metastatic Melanoma.

Published in:

Molecular Therapy, 2015, v. 23, n. 8, p. 1380, doi. 10.1038/mt.2015.71

By:

Beane, Joal D;
Lee, Gary;
Zheng, Zhili;
Mendel, Matthew;
Abate-Daga, Daniel;
Bharathan, Mini;
Black, Mary;
Gandhi, Nimisha;
Yu, Zhiya;
Chandran, Smita;
Giedlin, Martin;
Ando, Dale;
Miller, Jeff;
Paschon, David;
Guschin, Dmitry;
Rebar, Edward J;
Reik, Andreas;
Holmes, Michael C;
Gregory, Philip D;
Restifo, Nicholas P

Publication type:

Article

In This Issue.

Published in:: Molecular Therapy, 2015, v. 23, n. 6, p. 978, doi. 10.1038/mt.2015.81
Publication type:: Article

Efficient and Allele-Specific Genome Editing of Disease Loci in Human iPSCs.

Published in:

Molecular Therapy, 2015, v. 23, n. 3, p. 570, doi. 10.1038/mt.2014.226

By:

Smith, Cory;
Abalde-Atristain, Leire;
He, Chaoxia;
Brodsky, Brett R;
Braunstein, Evan M;
Chaudhari, Pooja;
Jang, Yoon-Young;
Cheng, Linzhao;
Ye, Zhaohui

Publication type:

Article

Generation of an HIV Resistant T-cell Line by Targeted 'Stacking' of Restriction Factors.

Published in:

Molecular Therapy, 2013, v. 21, n. 4, p. 786, doi. 10.1038/mt.2012.284

By:

Voit, Richard A;
McMahon, Moira A;
Sawyer, Sara L;
Porteus, Matthew H

Publication type:

Article

Plant genome editing with TALEN and CRISPR.

Published in:

Cell & Bioscience, 2017, v. 7, p. 1, doi. 10.1186/s13578-017-0148-4

By:

Malzahn, Aimee;
Lowder, Levi;
Yiping Qi

Publication type:

Article

Genomic editing opens new avenues for zebrafish as a model for neurodegeneration.

Published in:

Journal of Neurochemistry, 2013, v. 127, n. 4, p. 461, doi. 10.1111/jnc.12460

By:

Schmid, Bettina;
Haass, Christian

Publication type:

Article

E-CRISP: fast CRISPR target site identification.

Published in:

Nature Methods, 2014, v. 11, n. 2, p. 122, doi. 10.1038/nmeth.2812

By:

Heigwer, Florian;
Kerr, Grainne;
Boutros, Michael

Publication type:

Article

Model organisms: Conditional gene knockouts in worms.

Published in:: Nature Methods, 2013, v. 10, n. 10, p. 933, doi. 10.1038/nmeth.2668
Publication type:: Article

A revolution coming to a classic model organism.

Published in:

Nature Methods, 2013, v. 10, n. 4, p. 303, doi. 10.1038/nmeth.2415

By:

Grunwald, David Jonah

Publication type:

Article

Robust, synergistic regulation of human gene expression using TALE activators.

Published in:

Nature Methods, 2013, v. 10, n. 3, p. 243, doi. 10.1038/nmeth.2366

By:

Maeder, Morgan L;
Linder, Samantha J;
Reyon, Deepak;
Angstman, James F;
Fu, Yanfang;
Sander, Jeffry D;
Joung, J Keith

Publication type:

Article

Improving gene-editing nucleases.

Published in:

Nature Methods, 2012, v. 9, n. 6, p. 536, doi. 10.1038/nmeth.2060

By:

de Souza, Natalie

Publication type:

Article

An optimized two-finger archive for ZFN-mediated gene targeting.

Published in:

Nature Methods, 2012, v. 9, n. 6, p. 588, doi. 10.1038/nmeth.1994

By:

Gupta, Ankit;
Christensen, Ryan G;
Rayla, Amy L;
Lakshmanan, Abirami;
Stormo, Gary D;
Wolfe, Scot A

Publication type:

Article

Targeted editing of goat genome with modular-assembly zinc finger nucleases based on activity prediction by computational molecular modeling.

Published in:

Molecular Biology Reports, 2013, v. 40, n. 7, p. 4251, doi. 10.1007/s11033-013-2507-5

By:

Xiong, Kai;
Li, Shanshan;
Zhang, Hongxiao;
Cui, Ye;
Yu, Debing;
Li, Yan;
Sun, Wenxing;
Fu, Yingying;
Teng, Yun;
Liu, Zhi;
Zhou, Xiaolong;
Xiao, Peng;
Li, Juan;
Liu, Honglin;
Chen, Jie

Publication type:

Article

A history of genome editing in mammals.

Published in:

Mammalian Genome, 2017, v. 28, n. 7/8, p. 237, doi. 10.1007/s00335-017-9699-2

By:

Fernández, Almudena;
Josa, Santiago;
Montoliu, Lluis

Publication type:

Article

CRISPR/Cas9 und andere Genome Editing Techniken.

Published in:

2017

By:

Hartung, Frank

Publication type:

Abstract

Highly efficient multiplex human T cell engineering without double-strand breaks using Cas9 base editors.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-13007-6

By:

Webber, Beau R.;
Lonetree, Cara-lin;
Kluesner, Mitchell G.;
Johnson, Matthew J.;
Pomeroy, Emily J.;
Diers, Miechaleen D.;
Lahr, Walker S.;
Draper, Garrett M.;
Slipek, Nicholas J.;
Smeester, Branden A.;
Lovendahl, Klaus N.;
McElroy, Amber N.;
Gordon, Wendy R.;
Osborn, Mark J.;
Moriarity, Branden S.

Publication type:

Article

Engineered amphiphilic peptides enable delivery of proteins and CRISPR-associated nucleases to airway epithelia.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-12922-y

By:

Krishnamurthy, Sateesh;
Wohlford-Lenane, Christine;
Kandimalla, Suhas;
Sartre, Gilles;
Meyerholz, David K.;
Théberge, Vanessa;
Hallée, Stéphanie;
Duperré, Anne-Marie;
Del'Guidice, Thomas;
Lepetit-Stoffaes, Jean-Pascal;
Barbeau, Xavier;
Guay, David;
McCray, Paul B.

Publication type:

Article

Genome Editing: A New Horizon for Oral and Craniofacial Research.

Published in:

2019

By:

Yu, N.;
Yang, J.;
Mishina, Y.;
Giannobile, W. V.

Publication type:

journal article

DNA2--An Important Player in DNA Damage Response or Just Another DNA Maintenance Protein?

Published in:

International Journal of Molecular Sciences, 2017, v. 18, n. 7, p. 1562, doi. 10.3390/ijms18071562

By:

Pawłowska, Elzbieta;
Szczepanska, Joanna;
Blasiak, Janusz

Publication type:

Article

Homologous Recombination-Independent Large Gene Cassette Knock-in in CHO Cells Using TALEN and MMEJ-Directed Donor Plasmids.

Published in:

International Journal of Molecular Sciences, 2015, v. 16, n. 10, p. 23849, doi. 10.3390/ijms161023849

By:

Tetsushi Sakuma;
Mitsumasa Takenaga;
Yoshinori Kawabe;
Takahiro Nakamura;
Masamichi Kamihira;
Takashi Yamamoto

Publication type:

Article