Works matching DE "NUCLEAR factor E2 related factor"

Results: 2591

Repurposing the familiar: Future treatment options against chronic kidney disease.

Published in:

Journal of Pharmacy & Pharmacology, 2025, v. 77, n. 6, p. 715, doi. 10.1093/jpp/rgaf002

By:

Bhadange, Rohan;
Gaikwad, Anil Bhanudas

Publication type:

Article

Piperlongumine inhibits glioblastoma proliferation by inducing ferroptosis.

Published in:

Journal of Pharmacy & Pharmacology, 2025, v. 77, n. 6, p. 822, doi. 10.1093/jpp/rgae148

By:

Qiu, Jianting;
Guo, Fangzhou;
Shi, Ji;
Guo, Tangjun;
Piao, Haozhe

Publication type:

Article

白花蛇舌草提取液对日光性皮炎小鼠的保护作用及机制研究.

Published in:

China Surfactant Detergent & Cosmetics (2097-2806), 2025, v. 55, n. 5, p. 581, doi. 10.3969/j.issn.2097-2806.2025.05.006

By:

马悦文;
李小静;
黄雪锋;
陈贤;
王春丽

Publication type:

Article

Oviductal Sperm Storage Activates the NRF2 Antioxidant Pathway in Mauremys reevesii.

Published in:

International Journal of Morphology, 2025, v. 43, n. 3, p. 968

By:

Xing Yu;
Xinyue Lin;
Wenyan Wang;
Guojun Zhang;
Xingquan Xia;
Liuwang Nie;
Xingjiang Bu

Publication type:

Article

NRF2 maintains redox balance via ME1 and NRF2 inhibitor synergizes with venetoclax in NPM1-mutated acute myeloid leukemia.

Published in:

Cancer & Metabolism, 2025, v. 13, n. 1, p. 1, doi. 10.1186/s40170-025-00401-6

By:

Hu, Jiayuan;
Yuan, Zihao;
Shu, Yan;
Ren, Jun;
Yang, Jing;
Tang, Lisha;
Wei, Xingyu;
Liu, Yongcan;
Jin, Fangfang;
Xiao, Qiaoling;
Chen, Xinyi;
Wu, Nan;
Zhao, Wen;
Li, Ziwei;
Zhang, Ling

Publication type:

Article

Dimethyl Citraconate Alleviates Periodontitis via Activating the NRF2 Cascade.

Published in:

Journal of Dental Research, 2025, v. 104, n. 8, p. 910, doi. 10.1177/00220345251319249

By:

Wang, Y.;
Li, Y.;
Cai, Y.;
Yang, X.;
Li, H.;
Wang, Q.;
Huang, D.;
Liu, L.;
Fan, Z.;
Yuan, Q.

Publication type:

Article

Cisplatin induces hippocampal neurotoxicity and cognitive impairment in rats through neuroinflammation, oxidative stress, and overexpression of glutamatergic receptors mRNA.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1592511

By:

Alhowail, Ahmad Hamad

Publication type:

Article

Modified ZhuJing pill protects retinal pigment epithelium against oxidative stress-induced epithelial–mesenchymal transition through Nrf2-mediated Akt/GSK3β pathway.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1545731

By:

Yang, Ning;
Xiong, Caijian;
Feng, Siqi;
Gao, Mengqi;
Zhou, Siqi;
Hui, Qinyi;
Zhou, Xin;
Jin, Qingzi;
Shao, Yan;
Xu, Xinrong

Publication type:

Article

Lymphatic Metastasis of Esophageal Squamous Cell Carcinoma: The Role of NRF2 and Therapeutic Strategies.

Published in:

Cancers, 2025, v. 17, n. 11, p. 1853, doi. 10.3390/cancers17111853

By:

Li, Yahui;
Ladd, Zachary;
Xiong, Zhaohui;
Bui-Linh, Candice;
Paiboonrungruang, Chorlada;
Subramaniyan, Boopathi;
Li, Huan;
Wang, Haining;
Balch, Curt;
Shersher, David D.;
Spitz, Francis;
Chen, Xiaoxin

Publication type:

Article

Fisetin Attenuates Zinc Overload-Induced Hepatotoxicity in Mice via Autophagy-Dependent Nrf2 Activation.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 11, p. 4978, doi. 10.3390/ijms26114978

By:

Huang, Feifei;
Wang, Zhonghang;
Zhou, Mohan;
Zhang, Qian;
Feng, Jie

Publication type:

Article

AS-IV Attenuates Oxidative Stress-Induced Apoptosis in Zebrafish via Modulation of the AKT/NRF2/HO-1/Caspase-3 Signaling Axis.

Published in:

Molecules, 2025, v. 30, n. 11, p. 2355, doi. 10.3390/molecules30112355

By:

Dai, Jili;
E, Zhizhou;
Bi, Yannan;
Yin, Zetao;
Wang, Yanfang;
Wang, Xingyu;
Jia, Xiaoe;
Zou, Bo

Publication type:

Article

The gut microbiota-mediated ferroptosis pathway: a key mechanism of ginsenoside Rd against metabolism-associated fatty liver disease.

Published in:

Chinese Medicine, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13020-025-01121-1

By:

Liu, Wenjing;
Zhou, Xian;
Xiao, Liyu;
Huang, Xiaolan;
Chang, Dennis;
Zhong, Xiaomei;
Zeng, Minjie;
Xian, Yanfang;
Zheng, Yanfang;
Huang, Wei;
Huang, Rui;
Huang, Mingqing

Publication type:

Article

Triglyceride-Glucose Index predicts type 2 diabetes risk and progression of diabetic nephropathy: a critical appraisal.

Published in:

International Journal of Diabetes in Developing Countries, 2025, v. 45, n. 2, p. 253, doi. 10.1007/s13410-025-01487-w

By:

Chawla, Rajeev

Publication type:

Article

Comprehensive gene expression analysis of histone deacetylases and the transcription factor Nrf2 in the progression of diabetic nephropathy.

Published in:

International Journal of Diabetes in Developing Countries, 2025, v. 45, n. 2, p. 462, doi. 10.1007/s13410-024-01362-0

By:

Harithpriya, Kannan;
Juttada, Udyama;
Jayasuriya, Ravichandran;
Kumpatla, Satyavani;
Viswanathan, Vijay;
Ramkumar, Kunka Mohanram

Publication type:

Article

Kaempferol inhibits oxidative stress and reduces macrophage pyroptosis by activating the NRF2 signaling pathway.

Published in:

PLoS ONE, 2025, v. 20, n. 6, p. 1, doi. 10.1371/journal.pone.0325189

By:

Wang, Yu;
Chen, Chaofan;
Li, Yushan;
Li, Ran;
Wang, Jinghan;
Wu, Chao;
Chen, Haonan;
Shi, Yingchao;
Wang, Shengfang;
Gao, Chuanyu

Publication type:

Article

Human umbilical cord mesenchymal stem cell-derived exosomes mitigate acute radiation-induced intestinal oxidative damage via the Nrf2/HO-1/NQO1 signaling pathway.

Published in:

PLoS ONE, 2025, v. 20, n. 6, p. 1, doi. 10.1371/journal.pone.0324238

By:

Wang, Hongyu;
Wang, Jinbao;
Yang, Gaosheng;
Li, Yanjie;
Chen, Weikai;
Yu, Jianping;
Han, Xiaopeng

Publication type:

Article

Mechanistic evaluation of a traditional herbal decoction in attenuating hepatic fibrosis via Nrf2/GPX4 pathway activation and ferroptosis inhibition.

Published in:

Hereditas, 2025, v. 162, n. 1, p. 1, doi. 10.1186/s41065-025-00471-y

By:

Liu, Jing-Jing;
Zhou, Xiao-qi;
Zhou, Jia-Lin;
Tong, Li-Jun;
Hu, Ling-Xiang;
Liu, Xiang;
Hu, Li-Mei;
Zhou, Chang-Xiao;
Dai, Qi

Publication type:

Article

Acetamiprid-induced testicular toxicity in mice: ameliorative effect and potential mechanisms of morin.

Published in:

BMC Complementary Medicine & Therapies, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12906-025-04944-5

By:

Alemdar, Nihal Turkmen;
Demir, Selim;
Yulug, Esin;
Kulaber, Ali;
Demir, Elif Ayazoglu;
Erdogan, Nadire Sevdenur;
Mentese, Ahmet;
Aliyazicioglu, Yuksel

Publication type:

Article

Expression and Diagnostic Value of Nrf2 and p62 in Cervical Squamous Cell Carcinoma and Intraepithelial Lesions.

Published in:

Cancer Management & Research, 2025, v. 17, p. 1005, doi. 10.2147/CMAR.S513226

By:

Wei, Wei;
Hu, Xingyan;
Han, Qing

Publication type:

Article

EZH1 deficiency promotes ferroptosis resistance by activating NRF2 in sepsis-associated liver injury.

Published in:

Clinical Epigenetics, 2025, v. 17, n. 1, p. 1, doi. 10.1186/s13148-025-01892-2

By:

Mei, Meihua;
You, Ying;
Tan, Ningxin;
He, Xiaoshun;
Huang, Junqi

Publication type:

Article

Empagliflozin ameliorates RSL3-induced ferroptosis in vascular endothelial cells via the NRF2/HO-1 pathway.

Published in:

BMC Cardiovascular Disorders, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12872-025-04890-7

By:

Wang, ZiLin;
Liu, SiMiao;
Shi, JiaHao;
Chen, Di;
Li, ShaoLin;
Yu, ShengQin;
Liu, SiXu;
Yang, KaiJing;
Zhang, Wan;
Gao, Xue;
Zhang, ShuYing

Publication type:

Article

Flotillin- 1 ameliorates experimental diabetic retinopathy by inhibiting ferroptosis in blood-retinal barrier.

Published in:

Journal of Molecular Medicine, 2025, v. 103, n. 6, p. 671, doi. 10.1007/s00109-025-02544-x

By:

Zhang, Jie;
Chang, Ke;
Shangguan, Yanyu;
Luo, Ruoning;
Bi, Yanlong;
Yu, Zicheng;
Li, Bing

Publication type:

Article

Multiple sclerosis: the role of NRF2 in the context of new therapies.

Published in:

European Journal of Clinical & Experimental Medicine, 2025, v. 23, p. 82

By:

Florek, Wiktoria;
Czech, Sara;
Szpara, Jakub;
Sowa-Kućma, Magdalena;
Pańczyszyn-Trzewik, Patrycja

Publication type:

Article

Activation of Nrf2 as novel molecular mechanism of antidepressants.

Published in:

European Journal of Clinical & Experimental Medicine, 2025, v. 23, p. 71

By:

Tomaka, Emilia;
Pańczyszyn-Trzewik, Patrycja;
Sowa-Kućma, Magdalena

Publication type:

Article

Alantolactone protects against doxorubicin-induced nephrotoxicity by modulating Nrf2/HO-1, NF-κB, and Bax/Bcl-2 activity: molecular and in silico insights.

Published in:

Molecular Biology Reports, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s11033-025-10620-1

By:

Abuzinadah, Mohammed F.;
Shaik, Rasheed A.;
Ahmad, Aftab;
Islam, Mohammed Nazrul;
Eid, Basma G.

Publication type:

Article

TRIM19 enhances the chemosensitivity of endometrial cancer by regulating the TBX2/NRF2 axis.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02717-7

By:

Ding, Ning;
Li, Yujiao;
Yu, Xiaohui

Publication type:

Article

Hypoxia-inducible factor-1 alpha and nuclear factor erythroid 2-related factor 2 as biomarkers of renal scarring in children with congenital anomalies of the kidney and urinary tract: a prospective case-control study.

Published in:

BMC Nephrology, 2025, v. 26, n. 1, p. 1, doi. 10.1186/s12882-025-04193-1

By:

Gençler, Aylin;
Çelik, Hakim;
Padalı, Fatih;
Demir, Abit;
Kafadar, Safiye

Publication type:

Article

Effect of xylitol on low‑density lipoprotein‑stimulated oxidative stress in THP‑1 cells.

Published in:

Molecular Medicine Reports, 2025, v. 32, n. 1, p. N.PAG, doi. 10.3892/mmr.2025.13555

By:

Huang, Zile;
Li, Anke;
Huang, Rui;
Shi, Mengmeng;
Yang, Rujing;
Wang, Wenyan;
Huang, Zhen;
Liu, Yanhong;
Wu, Junzhu

Publication type:

Article

Eburicoic acid inhibits endothelial cell pyroptosis and retards the development of atherosclerosis through the Keap1/Nrf2/HO‑1/ROS pathway.

Published in:

Molecular Medicine Reports, 2025, v. 32, n. 1, p. N.PAG, doi. 10.3892/mmr.2025.13551

By:

Ma, Meng-Qing;
Yang, Chun;
Jin, Shi-Yu;
Yang, Yu;
Pan, Yan-Yan;
Lin, Xian-He

Publication type:

Article

Cuproptosis-related gene signatures define the immune microenvironment in diabetic nephropathy.

Published in:

PLoS ONE, 2025, v. 20, n. 6, p. 1, doi. 10.1371/journal.pone.0321636

By:

Luo, Hongmin;
Cao, Yuxuan;
Guo, Liping;
Li, Hui;
Yuan, Yingying;
Lu, Fan

Publication type:

Article

COMPUTATIONAL VALIDATION OF BIO-ACTIVE COMPOUNDS FROM EMBLICA OFFICINALIS GAERTN. AGAINST THE NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR 2 (NFE2L2) IN TYPE 2 DIABETES MELLITUS.

Published in:

Indian Drugs, 2025, v. 62, n. 3, p. 38, doi. 10.53879/id.62.03.14906

By:

Tripathy, Chandra S.;
Behera, Santosh K.;
Parida, Sagarika

Publication type:

Article

Protective mechanisms of icariin in methotrexate-induced renal damage: role of Nrf2/HO-1 and apoptosis reduction.

Published in:

Journal of Complementary & Integrative Medicine, 2025, v. 22, n. 2, p. 335, doi. 10.1515/jcim-2024-0431

By:

Mishra, Riya

Publication type:

Article

Research progress on the therapeutic effects of effective components of traditional Chinese medicine in the treatment of gastric cancer precursors through modulation of multiple signaling pathways.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1555274

By:

Han, Lichao;
Ma, Yijia;
Wu, Weidong;
Ni, Qianyue;
Xie, Jingri;
Huang, Yan;
Jin, Qiuyu;
Wu, Lili;
Zhang, Yang

Publication type:

Article

Prunus persica Leaf Extract Mitigates Ultraviolet-Induced Skin Damage Via Activation of AMP-Activated Protein Kinase.

Published in:

Natural Product Communications, 2025, v. 20, n. 4, p. 1, doi. 10.1177/1934578X251330952

By:

Kim, Eun Ok;
Lee, Dae Geon;
Jung, Cheol Jong;
Yu, Yeong Eun;
Hong, Museok;
Cho, Il Je;
Ku, Sae Kwang

Publication type:

Article

Correction to "Magnetic graphene oxide increases the biocompatibility and nuclear factor erythroid 2-related factor 2 antioxidant of human cumulus cells: A lab-trial study" [Int J Reprod BioMed 2024; 22: 709-716].

Published in:: International Journal of Reproductive Biomedicine, 2025, v. 23, n. 3, p. 289, doi. 10.18502/ijrm.v23i3.18769
Publication type:: Article

Acrolein-Triggered Ferroptosis and Protection by Intermittent Fasting via the AMPK/NRF2-CLOCK/BMAL1 Pathway.

Published in:

Toxics, 2025, v. 13, n. 5, p. 369, doi. 10.3390/toxics13050369

By:

Zhang, Yuandie;
Chen, Hong;
Chen, Qianfeng;
Zaitoun, Margaret;
Cheng, Ying;
Ge, Jierong;
Feng, Qing

Publication type:

Article

Stachydrine from Natural Foods Alleviates Hyperuricemia by Modulating Renal Urate Transporters and Suppressing Mitochondrial Oxidative Stress.

Published in:

Foods, 2025, v. 14, n. 10, p. 1718, doi. 10.3390/foods14101718

By:

Guo, Jian;
Jia, Jinhui;
Wang, Ailin;
Gu, Yunqi;
Xia, Xiaodong

Publication type:

Article

Bioinformatics-Assisted Discovery of Antioxidant Cyclic Peptides from Corn Gluten Meal.

Published in:

Foods, 2025, v. 14, n. 10, p. 1709, doi. 10.3390/foods14101709

By:

Liu, Hongcheng;
Sun, Tong;
Gao, He;
Liu, Xiaolong;
Zhang, Shanshan;
Liu, Tingting;
Wang, Dawei;
Fan, Hongxiu;
Zhang, Yanrong

Publication type:

Article

Rutaecarpine Protects Human Endothelial Cells from Oxidative-Stress-Induced Apoptosis via TRPV1- and AhR-Mediated Nrf2 Activation.

Published in:

Antioxidants, 2025, v. 14, n. 5, p. 616, doi. 10.3390/antiox14050616

By:

Kim, Chae Yeon;
Lee, Gi Ho;
Lee, Seung Yeon;
Bui, Anh Thi Ngoc;
Jeong, Hye Gwang

Publication type:

Article

Targeting Lysosomal Dysfunction and Oxidative Stress in Age-Related Macular Degeneration.

Published in:

Antioxidants, 2025, v. 14, n. 5, p. 596, doi. 10.3390/antiox14050596

By:

Falcão, Ana S.;
Pedro, Margarida L.;
Tenreiro, Sandra;
Seabra, Miguel C.

Publication type:

Article

Vitamin C Inhibits Scale Drop Disease Virus Infectivity by Targeting Nrf2 to Reduce Ferroptosis.

Published in:

Antioxidants, 2025, v. 14, n. 5, p. 576, doi. 10.3390/antiox14050576

By:

Chen, Jiaming;
Fu, Yuting;
Weng, Shaoping;
He, Jianguo;
Dong, Chuanfu

Publication type:

Article

Dietary 5-Aminolevulinic Acid Alleviates Heat Stress-Induced Renal Injury in Laying Hens by Improving Mitochondrial Quality and Enhancing Antioxidant Activity.

Published in:

Antioxidants, 2025, v. 14, n. 5, p. 556, doi. 10.3390/antiox14050556

By:

Nanto-Hara, Fumika;
Ohtsu, Haruhiko

Publication type:

Article

A Highly Potent Apomorphine Derivative Enhancing Neurite Outgrowth via Nrf2 Activation.

Published in:

Antioxidants, 2025, v. 14, n. 5, p. 537, doi. 10.3390/antiox14050537

By:

Ishima, Tamaki;
Osaka, Hitoshi;
Nagai, Ryozo;
Aizawa, Kenichi

Publication type:

Article

Predicting Clinical Response to Monoclonal TNF Inhibitors in Rheumatoid Arthritis: A Transcriptomic Approach Based on Transmembrane TNF Reverse Signaling and Nrf2 Activation.

Published in:

Diagnostics (2075-4418), 2025, v. 15, n. 10, p. 1232, doi. 10.3390/diagnostics15101232

By:

Diallo, Katy;
Degboé, Yannick;
Baron, Michel;
Bellin-Robert, Anaïs;
Boyer, Jean-Frédéric;
Ruyssen-Witrand, Adeline;
Constantin, Arnaud;
Rauwel, Benjamin;
Cantagrel, Alain;
Davignon, Jean-Luc

Publication type:

Article

Molecular Targets of Oxidative Stress: Focus on Nuclear Factor Erythroid 2–Related Factor 2 Function in Leukemia and Other Cancers.

Published in:

Cells (2073-4409), 2025, v. 14, n. 10, p. 713, doi. 10.3390/cells14100713

By:

Hasan, Syed K.;
Jayakumar, Sundarraj;
Espina Barroso, Eliezer;
Jha, Anup;
Catalano, Gianfranco;
Sandur, Santosh K.;
Noguera, Nelida I.

Publication type:

Article

Retraction Note: Candesartan Protects Against Cadmium-Induced Hepatorenal Syndrome by Affecting Nrf2, NF-κB, Bax/Bcl-2/Cyt-C, and Ang II/Ang 1–7 Signals.

Published in:

2025

By:

Kamel, Esam O.;
Gad-Elrab, Wail M.;
Ahmed, Mohammed A.;
Mohammedsaleh, Zuhair M.;
Hassanein, Emad H. M.;
Ali, Fares E. M.

Publication type:

Correction Notice

苦味受体 T2R38 激活对香烟烟雾暴露诱导人气道上皮 NuLi-1 细胞铁死亡的影响及其机制.

Published in:

Journal of Jilin University (Medicine Edition), 2025, v. 51, n. 2, p. 333, doi. 10.13481/j.1671⁃587X.20250207

By:

李亮;
周向东;
王杰;
徐超群;
朱梦霞;
余善君;
李琪

Publication type:

Article

Chemical Composition and Biological Activities of Torreya grandis Kernels: Characteristics of Polymethylene-Interrupted Fatty Acids and Polyphenolic Compounds and Their Potential Health Effects.

Published in:

Forests (19994907), 2025, v. 16, n. 5, p. 737, doi. 10.3390/f16050737

By:

Liu, Ran;
Zhou, Baogang;
Che, Kundian;
Gao, Wei;
Luo, Haoyuan;
Yang, Jialin;
Chen, Zhanjun;
Hu, Wenzhong

Publication type:

Article

Coix Seed Oil Alleviates Hyperuricemia in Mice by Ameliorating Oxidative Stress and Intestinal Microbial Composition.

Published in:

Nutrients, 2025, v. 17, n. 10, p. 1679, doi. 10.3390/nu17101679

By:

Wu, Guozhen;
Wang, Xinming;
Dong, Hongjing;
Yu, Jinqian;
Li, Tao;
Wang, Xiao

Publication type:

Article

Isochlorogenic Acid C Alleviates Allergic Asthma via Interactions Between Its Bioactive Form and the Gut Microbiome.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4864, doi. 10.3390/ijms26104864

By:

Xu, Jing-Yi;
Rong, Xiao-Juan;
Shen, Zhen;
Guo, Yun-Dan;
Zhang, Yi-Xuan;
Ding, Chen-Chen;
Wang, Yi;
Han, Yan-Xing;
Gao, Tian-Le;
Tie, Cai

Publication type:

Article