Works about NOTCH signaling pathway

Results: 1278

The role of notch signaling pathway in cancer: mechanistic insights, therapeutic potential, and clinical progress.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1567524

By:

Zhang, Haokun;
Hang, Wang;
Jing, ZhaoHui;
Liu, Bingyan;
Wang, Xiaoxiao;
Li, Yilin;
Luo, Huomin;
Lv, Huilin;
Tao, Xingyue;
Timashev, Peter;
Li, Yuzhen;
Li, Peifeng

Publication type:

Article

The role of notch signaling pathway and non-coding RNAs in cancer and inflammation: progress, therapeutic insights, and future directions.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1567040

By:

Nie, Rong-Zu;
Wang, Hang;
Wang, Shuang-Shuang;
Chen, Chen;
Luo, Huo-Min;
Zhang, Hao-Kun;
Jing, Zhao-Hui;
Li, Pei-Feng

Publication type:

Article

Therapeutic potential of natural products in ischemic stroke: targeting angiogenesis.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1579172

By:

Li, WenQiang;
Liu, E.;
Zhou, YiHao;
Liao, ZhiChao;
Wang, DongYan

Publication type:

Article

microRNAs 介导的炎症相关信号通路调控骨性关节炎软骨细胞功能的研究进展.

Published in:

Journal of Modern Medicine & Health, 2025, v. 41, n. 6, p. 1469, doi. 10.3969/j.issn.1009-5519.2025.06.037

By:

史振华;
王晓萍;
周明旺;
杨星;
高海源

Publication type:

Article

The Drosophila histone variant H2Av facilitates Notch signaling activity in a two-tier regulatory fashion.

Published in:

Cell Communication & Signaling, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12964-025-02333-6

By:

Chen, Yao;
Zhang, Xinyue;
Song, Yu;
Shen, Jie;
Zhang, Junzheng

Publication type:

Article

Epithelial Cell Dysfunction in Pulmonary Fibrosis: Mechanisms, Interactions, and Emerging Therapeutic Targets.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 6, p. 812, doi. 10.3390/ph18060812

By:

Wang, Jing;
Chao, Jie

Publication type:

Article

Synthetic biology of cell signaling.

Published in:

Natural Computing, 2016, v. 15, n. 1, p. 5, doi. 10.1007/s11047-015-9526-1

By:

Hansen, Jonathan;
Benenson, Yaakov

Publication type:

Article

Notch Signaling is Required for Dendritic Cell Maturation and T Cell Expansion in Paracoccidioidomycosis.

Published in:

Mycopathologia, 2018, v. 183, n. 5, p. 739, doi. 10.1007/s11046-018-0276-3

By:

Jannuzzi, Grasielle Pereira;
de Almeida, José Roberto Fogaça;
dos Santos, Suelen Silvana;
de Almeida, Sandro Rogério;
Ferreira, Karen Spadari

Publication type:

Article

Pharmacological Notch pathway inhibition leads to cell cycle arrest and stimulates ascl1 and neurogenin2 genes expression in dental pulp stem cells-derived neurospheres.

Published in:

Biotechnology Letters, 2019, v. 41, n. 6/7, p. 873, doi. 10.1007/s10529-019-02687-1

By:

Niapour, Ali;
Ghasemi Hamidabadi, Hatef;
Niapour, Nazila;
Mohammadi, Perham;
Sharifi Pasandi, Marzieh;
Malekzadeh, Vadoud

Publication type:

Article

The interaction between autophagy and the epithelial-mesenchymal transition mediated by NICD/ULK1 is involved in the formation of diabetic cataracts.

Published in:

Molecular Medicine, 2022, v. 28, n. 1, p. 1, doi. 10.1186/s10020-022-00540-2

By:

Ma, Jiyuan;
Ye, Wei;
Yang, Yunshu;
Wu, Tong;
Wang, Yafen;
Li, Ji;
Pei, Rui;
He, Mengmei;
Zhang, Luning;
Zhou, Jian

Publication type:

Article

Inflammatory macrophages interrupt osteocyte maturation and mineralization via regulating the Notch signaling pathway.

Published in:

Molecular Medicine, 2022, v. 28, n. 1, p. 1, doi. 10.1186/s10020-022-00530-4

By:

Wang, Shengfang;
Xiao, Lan;
Prasadam, Indira;
Crawford, Ross;
Zhou, Yinghong;
Xiao, Yin

Publication type:

Article

Estrogen Promotes the Proliferation and Migration of Endometrial Cancer Through the GPER‐Mediated NOTCH Pathway.

Published in:

Journal of Biochemical & Molecular Toxicology, 2025, v. 39, n. 2, p. 1, doi. 10.1002/jbt.70129

By:

Qi, Meng;
Jin, Yuxi;
Si, Lulu;
Fu, Hanlin;
Shi, Xiaojing;
Liu, Yana;
Wang, Yifan;
Guo, Ruixia

Publication type:

Article

Cadmium Reduces VE‐Cadherin Expression in Endothelial Cells Through Activation of the Notch Signaling Pathway.

Published in:

Journal of Biochemical & Molecular Toxicology, 2025, v. 39, n. 1, p. 1, doi. 10.1002/jbt.70115

By:

Zhang, Yuanqing;
Wang, Jie;
Huai, Tianran;
Wang, Xia;
Liu, Qiang;
Xing, Yan;
Chudnary, Maryam;
Meng, Xianli;
Dong, Liang;
Malashicheva, Anna;
Tian, Jinghui;
Liu, Ju

Publication type:

Article

Long noncoding RNA LBX2‐AS1 promotes colorectal cancer progression via binding with PTBP1 and stabilizing KAT2A expression.

Published in:

Journal of Biochemical & Molecular Toxicology, 2022, v. 36, n. 5, p. 1, doi. 10.1002/jbt.23020

By:

Zhao, Andong;
Wang, Yu;
Lin, Fuliang;
Bai, Keyun;
Gu, Chao

Publication type:

Article

Accelerated cell turnover 48 h after intestinal ischemia is NOTCH independent.

Published in:

Pediatric Surgery International, 2019, v. 35, n. 12, p. 1413, doi. 10.1007/s00383-019-04569-z

By:

Ben-Shahar, Y.;
Abassi, Z.;
Pollak, Y.;
Bitterman, A.;
Kreizman-Shefer, H.;
Koppelman, T.;
Fuhrer, A. E.;
Hayari, L.;
Sukhotnik, I.

Publication type:

Article

Expression Profile of NOTCH3 in Mouse Spermatogonia.

Published in:

Cells Tissues Organs, 2017, v. 204, n. 5/6, p. 283, doi. 10.1159/000481772

By:

Okada, Ryu;
Fujimagari, Megumi;
Koya, Eri;
Hirose, Yoshikazu;
Sato, Tomomi;
Nishina, Yukio

Publication type:

Article

Inhibition of Notch Signaling Ameliorates Acute Kidney Failure and Downregulates Platelet-Derived Growth Factor Receptor β in the Mouse Model.

Published in:

Cells Tissues Organs, 2015, v. 199, n. 2, p. 109, doi. 10.1159/000442463

By:

Kramer, Jan;
Schwanbeck, Ralf;
Pagel, Horst;
Cakiroglu, Figen;
Rohwedel, Jürgen;
Just, Ursula

Publication type:

Article

Mammary Development and Breast Cancer: a Notch Perspective.

Published in:

Journal of Mammary Gland Biology & Neoplasia, 2021, v. 26, n. 3, p. 309, doi. 10.1007/s10911-021-09496-1

By:

Chen, Weizhen;
Wei, Wei;
Yu, Liya;
Ye, Zi;
Huang, Fujing;
Zhang, Liyan;
Hu, Shiqi;
Cai, Cheguo

Publication type:

Article

Multifaceted regulation of Notch signaling by glycosylation.

Published in:

Glycobiology, 2021, v. 31, n. 1, p. 8, doi. 10.1093/glycob/cwaa049

By:

Pandey, Ashutosh;
Niknejad, Nima;
Jafar-Nejad, Hamed

Publication type:

Article

Sensitized genetic backgrounds reveal differential roles for EGF repeat xylosyltransferases in Drosophila Notch signaling.

Published in:

Glycobiology, 2018, v. 28, n. 11, p. 849, doi. 10.1093/glycob/cwy080

By:

Pandey, Ashutosh;
Li-Kroeger, David;
Sethi, Maya K;
Lee, Tom V;
Buettner, Falk FR;
Bakker, Hans;
Jafar-Nejad, Hamed

Publication type:

Article

ADAMTSL2 is an independent predictor for the prognosis of gastric cancer.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02259-y

By:

Zhu, Xiuling;
Cui, Zhongyuan;
Li, Shasha;
She, Yingzhen;
Wu, Zhixian

Publication type:

Article

CSF2 promotes chemoresistance in colorectal cancer by regulating Notch pathway.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02285-w

By:

Zhou, Hairong;
Gao, Zhenyuan;
Wu, Xiao;
Wang, Yaping;
Zhang, Lu

Publication type:

Article

New insights into Notch signaling as a crucial pathway of pancreatic cancer stem cell behavior by chrysin-polylactic acid-based nanocomposite.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-01846-3

By:

Ragab, Eman M.;
Gamal, Doaa M. El;
El-najjar, Fares F.;
Elkomy, Hager A.;
Ragab, Mahmoud A.;
Elantary, Mariam A.;
Basyouni, Omar M.;
Moustafa, Sherif M.;
EL-Naggar, Shimaa A.;
Elsherbiny, Abeer S.

Publication type:

Article

Notch-Wnt signal crosstalk regulates proliferation and differentiation of osteoprogenitor cells during intramembranous bone healing.

Published in:

NPJ Regenerative Medicine, 2021, v. 6, n. 1, p. 1, doi. 10.1038/s41536-021-00139-x

By:

Lee, S.;
Remark, L. H.;
Josephson, A. M.;
Leclerc, K.;
Lopez, E. Muiños;
Kirby, D. J.;
Mehta, Devan;
Litwa, H. P.;
Wong, M. Z.;
Shin, S. Y.;
Leucht, P.

Publication type:

Article

Macular Perfusion Impairment in Von Hippel-Lindau Disease Suggests a Generalized Retinal Vessel Alteration.

Published in:

Journal of Clinical Medicine, 2020, v. 9, n. 8, p. 2677, doi. 10.3390/jcm9082677

By:

Pilotto, Elisabetta;
Nacci, Elisabetta Beatrice;
Ferrara, Alfonso Massimiliano;
De Mojà, Gilda;
Zovato, Stefania;
Midena, Edoardo

Publication type:

Article

Updates on the Role of Molecular Alterations and NOTCH Signalling in the Development of Neuroendocrine Neoplasms.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 9, p. 1277, doi. 10.3390/jcm8091277

By:

von Arx, Claudia;
Capozzi, Monica;
López-Jiménez, Elena;
Ottaiano, Alessandro;
Tatangelo, Fabiana;
Di Mauro, Annabella;
Nasti, Guglielmo;
Tornesello, Maria Lina;
Tafuto, Salvatore

Publication type:

Article

Intestinal Function and Integrity in Health and Disease: Current Knowledge in Swine.

Published in:

Journal of Animal Science, 2023, v. 101, p. 202, doi. 10.1093/jas/skad341.224

By:

Gabler, Nicholas K.;
Burrough, Eric R.

Publication type:

Article

Honokiol-Rich Magnolia officinalis Bark Extract Attenuates Trauma-Induced Neuropathic Pain.

Published in:

Antioxidants, 2023, v. 12, n. 8, p. 1518, doi. 10.3390/antiox12081518

By:

Borgonetti, Vittoria;
Galeotti, Nicoletta

Publication type:

Article

MicroRNA-124a promoted the differentiation of bone marrow mesenchymal stem cells into neurons through Notch signal pathway.

Published in:

European Journal of Medical Research, 2024, v. 29, n. 1, p. 1, doi. 10.1186/s40001-024-02061-6

By:

Wang, Daimei;
Jing, Lijun;
Zhao, Zhongyan;
Huang, Shixiong;
Xie, Ling;
Hu, Shijun;
Liang, Hui;
Chen, Yanquan;
Zhao, Eryi

Publication type:

Article

WD repeat domain 76 predicts poor prognosis in lower grade glioma and provides an original target for immunotherapy.

Published in:

European Journal of Medical Research, 2024, v. 29, n. 1, p. 1, doi. 10.1186/s40001-023-01605-6

By:

Cheng, Xingbo;
Liu, Zhendong;
Chang, Haigang;
Liang, Wenjia;
Li, Pengxu;
Gao, Yanzheng

Publication type:

Article

The Involvement of Notch1-RBP-Jk/Msx2 Signaling Pathway in Aortic Calcification of Diabetic Nephropathy Rats.

Published in:

Journal of Diabetes Research, 2017, p. 1, doi. 10.1155/2017/8968523

By:

Gong, Caipan;
Li, Li;
Qin, Chunmei;
Wu, Weihua;
Liu, Qi;
Li, Ying;
Gan, Linwang;
Ou, Santao

Publication type:

Article

Exploration of the Long Noncoding RNAs Involved in the Crosstalk between M2 Macrophages and Tumor Metabolism in Lung Cancer.

Published in:

Genetics Research, 2023, p. 1, doi. 10.1155/2023/4512820

By:

Fang, Fang;
Yao, Yuanshan;
Ma, Zhe

Publication type:

Article

A hub of activity.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.93706

By:

PIMMETT, VIRGINIA L.;
LAGHA, MOUNIA

Publication type:

Article

Relevance of Aberrations in Signal Transduction Pathways and Tumour Microenvironment in Colorectal Cancer for Cancer Precision Medicine.

Published in:

Malaysian Journal of Medicine & Health Sciences, 2017, v. 13, p. 13

By:

Wai Kien Yip;
Boon Lee Chai;
Wen Li Goh;
Boon Yean Chai;
Mohtarrudin, Norhafizah;
Jabar, Mohd Faisal;
Heng Fong Seow

Publication type:

Article

Angelica polysaccharide moderates hypoxia-evoked apoptosis and autophagy in rat neural stem cells by downregulation of BNIP3.

Published in:

Artificial Cells, Nanomedicine & Biotechnology, 2019, v. 47, n. 1, p. 2492, doi. 10.1080/21691401.2019.1623228

By:

Xue, Yongzhen;
Dongmei Li;
Yige Zhang;
Hang Gao;
Li, Hui

Publication type:

Article

Effects of Srxn1 on growth and Notch signalling of astrocyte induced by hydrogen peroxide.

Published in:

Artificial Cells, Nanomedicine & Biotechnology, 2019, v. 47, n. 1, p. 1917, doi. 10.1080/21691401.2019.1614016

By:

Li, Lan;
Lin, Guangjun;
Gu, Huizi;
Yu, Lei;
Ni, Changwei

Publication type:

Article

Study on the mechanism of PM2.5 affecting Th1/Th2 immune imbalance through the notch signaling pathway in asthmatic mice.

Published in:

Toxicology Research, 2023, v. 12, n. 4, p. 675, doi. 10.1093/toxres/tfad044

By:

Wu, Ji-rong;
He, Zheng;
Bao, Hai-rong;
Zeng, Xiao-li;
Liu, Xiao-ju

Publication type:

Article

Resveratrol inhibits AhR/Notch axis and reverses Th17/Treg imbalance in purpura by activating Foxp3.

Published in:

Toxicology Research, 2023, v. 12, n. 3, p. 381, doi. 10.1093/toxres/tfad021

By:

Cheng, Jing;
Wang, Sheng;
Lv, Shi-Qin;
Song, Yuan;
Guo, Ning-Hong

Publication type:

Article

Hypoxia-inducible factor-2a promotes EMT in esophageal squamous cell carcinoma through the Notch pathway.

Published in:

Advances in Clinical & Experimental Medicine, 2022, v. 31, n. 7, p. 795, doi. 10.17219/acem/147270

By:

Zhiqi Ji;
Shihao Bao;
Liang Li;
Dong Wang;
Mo Shi;
Xiangyan Liu

Publication type:

Article

Notch pathway activation promotes the differentiation of beagle dog periodontal ligament stem cells to Schwann cells.

Published in:

Advances in Clinical & Experimental Medicine, 2021, v. 30, n. 7, p. 721, doi. 10.17219/acem/131219

By:

Xiaojie Li;
Dapeng Liao;
Gang Sun;
HanWen Chu

Publication type:

Article

NELL2 suppresses epithelial-mesenchymal transition and induces ferroptosis via notch signaling pathway in HCC.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-94669-9

By:

Liu, Shiqi;
Wu, Haomin;
Zhang, Pengjie;
Zhou, Haonan;
Wu, Di;
Jin, Yifan;
Yang, Hongwei;
Xing, Ruilin;
Wu, Yubo;
Wu, Gang

Publication type:

Article

Radiation exposure induces genome-wide alternative splicing events in Aedes aegypti mosquitoes.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-94529-6

By:

Bendzus-Mendoza, Harley;
Rodriguez, Amanda;
Debnath, Tathagata;
Bailey, C. Donovan;
Luker, Hailey A.;
Hansen, Immo A.

Publication type:

Article

RNA sequencing analysis reveals that missense mutation in SOX10 is associated with iris color phenotype in quail.

Published in:

Animal Genetics, 2024, v. 55, n. 1, p. 79, doi. 10.1111/age.13371

By:

Ren, Shiwei;
Zhang, Xiaohui;
Pang, Youzhi;
Qi, Yanxia;
Huo, Linke;
Wu, Fanghu;
Shang, Yuanyuan;
Xi, Jinquan

Publication type:

Article

Editorial: Identification of effective biomarkers for diagnosis and treatment of chronic kidney disease: integrating bioinformatics and pharmacological approaches.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1606173

By:

Srivastava, Swayam Prakash;
Kanasaki, Keizo

Publication type:

Article

Editorial: Model organisms in predictive toxicology 2023.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1609126

By:

Luceri, Cristina;
Dogan, Abdulahad;
León-Buitimea, Angel

Publication type:

Article

Editorial: Targeting cellular signalling pathways for disease therapy: the potential of cellular reprogramming and protein kinase inhibitors.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1580686

By:

Marensi, Vanessa;
Oliveira, Pedro Fontes;
Zamoner, Ariane

Publication type:

Article

Enhanced tumor suppression in colorectal cancer via berberine-loaded PEG-PLGA nanoparticles.

Published in:

Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1500731

By:

Shen, Fei;
Zheng, Yun-Sheng;
Dong, Lan;
Cao, Ziyang;
Cao, Jie

Publication type:

Article

Modulation of Notch signaling pathway in activated hepatic stellate cells does not ameliorate the outcome of liver fibrosis in carbon tetrachloride and DDC-feeding models.

Published in:

Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1440236

By:

Šisl, Dino;
Planinić, Pavao;
Novak, Sanja;
Filipović, Maša;
Flegar, Darja;
Šućur, Alan;
Turčić, Petra;
Kovačić, Nataša;
Kalajzić, Ivo;
Grčević, Danka;
Kelava, Tomislav

Publication type:

Article

Notch Signaling in Ischemic Damage and Fibrosis: Evidence and Clues from the Heart.

Published in:

Frontiers in Pharmacology, 2017, v. 8, p. 1, doi. 10.3389/fphar.2017.00187

By:

Nistri, Silvia;
Sassoli, Chiara;
Bani, Daniele

Publication type:

Article

Histone Modifications Drive Aberrant Notch3 Expression/Activity and Growth in T-ALL.

Published in:

Frontiers in Oncology, 2019, p. N.PAG, doi. 10.3389/fonc.2019.00198

By:

Tottone, Luca;
Zhdanovskaya, Nadezda;
Carmona Pestaña, Álvaro;
Zampieri, Michele;
Simeoni, Fabrizio;
Lazzari, Sara;
Ruocco, Valeria;
Pelullo, Maria;
Caiafa, Paola;
Felli, Maria Pia;
Checquolo, Saula;
Bellavia, Diana;
Talora, Claudio;
Screpanti, Isabella;
Palermo, Rocco

Publication type:

Article