Works about NLRP3 protein

Results: 2945

Role of NLRP3 Inflammasome in Parkinson's Disease and Therapeutic Considerations.

Published in:

Journal of Parkinson's Disease, 2022, v. 12, n. 7, p. 2117, doi. 10.3233/JPD-223290

By:

Nguyen, Linh Thi Nhat;
Nguyen, Huu Dat;
Kim, Yun Joong;
Nguyen, Tinh Thi;
Lai, Thuy Thi;
Lee, Yoon Kyoung;
Ma, Hyeo-il;
Kim, Young Eun

Publication type:

Article

Inflammasome Activation in Parkinson's Disease.

Published in:

Journal of Parkinson's Disease, 2022, v. 12, p. S113, doi. 10.3233/JPD-223338

By:

Jewell, Shannon;
Herath, Ashane M.;
Gordon, Richard;
Bloem, Bastiaan R.;
Brundin, Patrik;
Tan, Eng King;
Harms, Ashley;
Lindestam Arlehamn, Cecilia;
Williams-Gray, Caroline

Publication type:

Article

Endoplasmic Reticulum Stress and NLRP3 Inflammasome Activation Underlie Silver Nanoparticles‐Induced Neurologic Deficits in Adult Mice.

Published in:

Journal of Biochemical & Molecular Toxicology, 2025, v. 39, n. 6, p. 1, doi. 10.1002/jbt.70289

By:

Zhang, Wenhui;
Zhai, Mengdi;
Wu, Meijia;
Yuan, Yongke;
Su, Xiao;
Yang, Mingzhi;
Ba, Yue;
Deng, Qihong;
Zhang, Yu;
Han, Lin;
Gao, Lihua;
Huang, Hui

Publication type:

Article

Erdafitinib diminishes LPS-mediated neuroinflammatory responses through NLRP3 in wild-type mice.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1572604

By:

Lee, Hyun-ju;
Kim, Se Ha;
Jung, Tae-Mi;
Kim, Yu-Jin;
Gu, Chan-Hu;
Jeong, Yoo Joo;
Song, Jeong-Heon;
Hoe, Hyang-Sook

Publication type:

Article

Tracing inflammasomes in Alzheimer's: insights from bibliometric analysis.

Published in:

Frontiers in Neurology, 2025, p. 1, doi. 10.3389/fneur.2025.1540083

By:

Chen, Yingjun;
Pei, Hui;
Li, Hao;
Zeng, Wenjun;
Li, Zhitao

Publication type:

Article

Env from EIAV vaccine delicately regulates NLRP3 activation via attenuating NLRP3-NEK7 interaction.

Published in:

PLoS Pathogens, 2025, v. 21, n. 6, p. 1, doi. 10.1371/journal.ppat.1012772

By:

Guo, Xing;
Liu, Cong;
Wang, Yuhong;
Li, Hongxin;
Ma, Saiwen;
Na, Lei;
Ren, Huiling;
Lin, Yuezhi;
Wang, Xiaojun

Publication type:

Article

ATP/P2X7 receptor/NLRP3 pathway facilitates renal tubular epithelial-myofibroblast transdifferentiation and interstitial fibrosis in rats with unilateral ureteral obstruction.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1598151

By:

Tan, Hui;
Li, Feiyan;
Cui, Yanchao;
Li, Ziwen;
Yan, Shiqiang;
Deng, Quanfeng

Publication type:

Article

The Role of the NLRP3 Inflammasome in Type 1 Diabetes: Insights From a Systematic Literature Review of Rodent Studies.

Published in:

Malaysian Journal of Medicine & Health Sciences, 2025, v. 21, n. 3, p. 457, doi. 10.47836/mjmhs.21.3.53

By:

Subramaniam, Shamala Devi;
Abas, Razif

Publication type:

Article

Inhibition of YAP can down-regulate NLRP3 inflammasome and improve anti-tuberculosis drug-induced liver injury.

Published in:

Xenobiotica, 2025, v. 55, n. 2, p. 131, doi. 10.1080/00498254.2025.2497050

By:

Long, Yifei;
Li, Xueying;
Liu, Yue;
Zhang, Mi;
Feng, Fumin

Publication type:

Article

Positive Airway Pressure Treatment Effects on the Serum Nod-like Receptor Protein 3 and Nitric Oxide Levels in Obstructive Sleep Apnea Syndrome.

Published in:

Clinical Psychopharmacology & Neuroscience, 2025, v. 23, n. 2, p. 227, doi. 10.9758/cpn.24.1235

By:

Cengiz, Emine Kılıçparlar;
Fırat, Yasemin Ekmekyapar;
Güngör, Meltem;
Berk, İhsan;
Neyal, Abdurrahman;
Saygılı, Eyüp İlker;
Neyal, Ayşe Münife

Publication type:

Article

NLRP3 Gene Promoter Region Polymorphisms; Relations with Inflammation on Obstructive Sleep Apnea Syndrome (OSAS).

Published in:

Suleyman Demirel University Faculty of Arts & Science Journal of Science / Süleyman Demirel Üniversitesi Fen Edebiyat Fakültesi Fen Dergisi, 2025, v. 20, n. 1, p. 75, doi. 10.29233/sdufeffd.1612135

By:

Şahin, Uğur;
Calapoğlu, Mustafa;
Öztürk, Önder;
Tülüceoğlu, Eda Evgen;
Calapoğlu, Nilüfer Şahin

Publication type:

Article

NOD2-NLRP3 Axis and Asthma.

Published in:

Journal of Asthma & Allergy, 2025, v. 18, p. 769, doi. 10.2147/JAA.S526788

By:

Cai, Xulong

Publication type:

Article

Targeting NLRP3 inflammasome attenuates cardiac pyroptosis and fibrosis in estrogen-deficient diabetic rats.

Published in:

Pflügers Archiv: European Journal of Physiology, 2025, v. 477, n. 7, p. 935, doi. 10.1007/s00424-025-03092-6

By:

Phungphong, Sukanya;
Suthivanich, Phichaya;
Boonhoh, Worakan;
Punsawad, Chuchard;
Cheng, Zhaokang;
Bupha-Intr, Tepmanas

Publication type:

Article

Exploring Treatment Adherence in Allergic Rhinitis, Inflammasome Mechanisms in Asthma, and Chronic Cough: Insights From Recent Studies.

Published in:

Clinical & Experimental Allergy, 2025, v. 55, n. 3, p. 210, doi. 10.1111/cea.70023

By:

Shamji, Mohamed H.;
Boyle, Robert J.

Publication type:

Article

NLRP1 Is a Prominent Inflammasome Sensor Found in Bronchial Epithelial Cells in Asthma and Can Be Activated by Rhinovirus A16.

Published in:

Clinical & Experimental Allergy, 2025, v. 55, n. 3, p. 239, doi. 10.1111/cea.70010

By:

Laanesoo, Anet;
Mäe, Mariel;
Remm, Anu;
Johnston, Sebastian L.;
Altraja, Alan;
Bochenek, Grazyna;
Jakiela, Bogdan;
Rebane, Ana

Publication type:

Article

Kaempferol inhibits oxidative stress and reduces macrophage pyroptosis by activating the NRF2 signaling pathway.

Published in:

PLoS ONE, 2025, v. 20, n. 6, p. 1, doi. 10.1371/journal.pone.0325189

By:

Wang, Yu;
Chen, Chaofan;
Li, Yushan;
Li, Ran;
Wang, Jinghan;
Wu, Chao;
Chen, Haonan;
Shi, Yingchao;
Wang, Shengfang;
Gao, Chuanyu

Publication type:

Article

Cross-talk between NLRP3 and AIM2 inflammasomes in macrophage activation by LPS and titanium ions.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01290-7

By:

Carrillo-Gálvez, Ana Belén;
Guerra-Valverde, José Antonio;
Padial-Molina, Miguel;
Martínez-Cuevas, Andrea;
Abril-García, Darío;
Olaechea, Allinson;
Martín-Morales, Natividad;
O'Valle, Francisco;
Galindo-Moreno, Pablo;
Zurita, Federico

Publication type:

Article

NLRP3 activation promotes cGAS/STING signaling and antitumor immunity by colorectal cancer cells.

Published in:

Cancer Immunology, Immunotherapy, 2025, v. 74, n. 8, p. 1, doi. 10.1007/s00262-025-04088-y

By:

Mowat, Courtney;
Schiller, Daniel;
Baker, Kristi

Publication type:

Article

NLRP3 inflammasome expression affects immune cell infiltration and clinical prognosis in Helicobacter pylori infection‑associated gastric cancer.

Published in:

Molecular Medicine Reports, 2025, v. 32, n. 1, p. N.PAG, doi. 10.3892/mmr.2025.13550

By:

Wan, Chuandan;
Xu, Yeqiong;
Zhu, Yanping;
Cao, Xuexian;
Wang, Ping;
Gu, Yulan

Publication type:

Article

Exosomal miR-202-5p derived from iPSC-MSCs protects against myocardial infarction through inhibition of cardiomyocyte pyroptosis.

Published in:

Stem Cell Research & Therapy, 2025, v. 16, n. 1, p. 1, doi. 10.1186/s13287-025-04390-7

By:

Chen, Jiaqi;
Liang, Xiaoting;
Han, Qian;
He, Haiwei;
Huang, Xinran;
Shen, Ying;
Qiu, Jie;
Lin, Fang;
Mai, Cong;
Li, Ziqi;
Ma, Kexin;
Hu, Bei;
Li, Xin;
Zhang, Yuelin

Publication type:

Article

Research and progress of cGAS/STING/NLRP3 signaling pathway: a mini review.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1594133

By:

Chen, Ke-qian;
Tang, Wen-rui;
Liu, Xiang

Publication type:

Article

Transcriptomic and Immunopathological Profiles of Inflammasomes in Different Clinical Forms of American Cutaneous Leishmaniasis.

Published in:

Microorganisms, 2025, v. 13, n. 5, p. 980, doi. 10.3390/microorganisms13050980

By:

Alcântara, Larissa dos Santos;
Campos, Marliane Batista;
Lima, Ana Carolina Stocco;
Pontillo, Alessandra;
Souza, Kamilla Batista da Silva;
Ferreira, Aurea Favero;
Camargo, Cristina Pires;
Oba-Shinjo, Sueli Mieko;
Laurenti, Márcia Dalastra;
Corbett, Carlos Eduardo Pereira;
da Matta, Vania L. R.;
Nakaya, Helder;
Silveira, Fernando T.;
Gomes, Claudia Maria de Castro

Publication type:

Article

Paeoniflorin Alleviates Lipopolysaccharide-Induced Neuroinflammation and Depression Through the Keap1/Nrf2/HO-1 Signaling Pathway.

Published in:

Antioxidants, 2025, v. 14, n. 5, p. 585, doi. 10.3390/antiox14050585

By:

Hu, Zhuoyue;
Wang, Xing;
Shi, Tian;
Yang, Lei;
Zhang, Boxi;
Shang, Bo;
He, Ruizhi;
Yi, Shichen;
He, Jiao;
Hu, Jing;
Cao, Yanjun

Publication type:

Article

Gingival Inflammation Modulates NLRP3 Inflammasome Signalling in Peripheral Blood Mononuclear Cells of PCOS Patients: A Case-Control Study.

Published in:

Antioxidants, 2025, v. 14, n. 5, p. 507, doi. 10.3390/antiox14050507

By:

Márquez-Arrico, Cecilia Fabiana;
Pelechá-Salvador, María;
Fernández-Reyes, Meylin;
Silvestre, Francisco Javier;
Perea-Galera, Laura;
Hermenejildo, Jonathan;
Abad-Jiménez, Zaida;
Silvestre-Rangil, Javier;
Morillas, Carlos;
Víctor, Víctor M.;
López-Domènech, Sandra;
Rocha, Milagros

Publication type:

Article

Shikonin inhibits NLRP3 inflammasome activation and controls inflammatory disease.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-03512-8

By:

Huang, Jing;
Dai, Mengmeng;
Huang, Xinyu;
Qi, Wenqing;
Jing, Jing;
He, Jiayi;
Lu, Zhizhuo;
Zhang, Chaofang;
Wang, Guiling;
Ma, Yuanfang;
Zhang, Hailong;
Cao, Run

Publication type:

Article

Hirudin Alleviates Early Brain Injury After Subarachnoid Hemorrhage in Rats via Regulating NLRP3 Inflammasome-Mediated Pyroptosis.

Published in:

Physiological Research, 2025, v. 74, n. 2, p. 301, doi. 10.33549/physiolres.935454

By:

Mingfu PAN;
Haiping CHEN;
Yang ZHAI;
Wei LONG;
Yuandai LUO

Publication type:

Article

Carbon dots from purple sweet potato as a promising anti-inflammatory biomaterial for alleviating the LPS-induced inflammation in macrophages.

Published in:

Journal of Nanobiotechnology, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12951-025-03494-9

By:

Jiang, Jiebang;
Pan, Zhiyuan;
Su, Yiren;
Dai, Lu;
Xu, Nana;
Wu, Han;
Chen, Xin

Publication type:

Article

Plasma Zinc Levels in Patients with Diabetic Nephropathy: Is there a Relationship with NLRP3 Inflammasome Activation and Renal Prognosis?

Published in:

Biological Trace Element Research, 2025, v. 203, n. 5, p. 2550, doi. 10.1007/s12011-024-04369-0

By:

Zhu, Yuexin;
Kang, Dedong;
Bai, Xiaoying;
Luo, Ping;
Du, Bing;
Li, Bing

Publication type:

Article

The NLRP3 inflammasome: a therapeutic target of phytochemicals in treating atherosclerosis (a systematic review).

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1568722

By:

Liu, Yongchao;
Wu, Qianyi;
Shao, Jing;
Mei, Youmin;
Zhang, Jie;
Xu, Qiuyun;
Mao, Liming

Publication type:

Article

Unexplained fever with consumptive syndrome in the elderly: two cases of VEXAS syndrome with inflammasome dysregulation.

Published in:

Clinical & Experimental Immunology, 2024, v. 218, n. 2, p. 213, doi. 10.1093/cei/uxae069

By:

Mendonça, Leonardo Oliveira;
Leal, Vinicius N C;
Roa, Mariela E G V;
Barros, Samar Freschi;
Kalil, Jorge;
Pontillo, Alessandra

Publication type:

Article

PDE10A Inhibition Reduces NLRP3 Activation and Pyroptosis in Sepsis and Nerve Injury.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4498, doi. 10.3390/ijms26104498

By:

Berk, Bradford C.;
Chávez, Camila Lage;
George Hsu, Chia

Publication type:

Article

Rescuing fertility during COVID-19 infection: exploring potential pharmacological and natural therapeutic approaches for comorbidity, by focusing on NLRP3 inflammasome mechanism.

Published in:

Journal of Assisted Reproduction & Genetics, 2023, v. 40, n. 5, p. 1173, doi. 10.1007/s10815-023-02768-1

By:

Hosseini, Elham;
Kohan-Ghadr, Hamid-Reza;
Bazrafkan, Mahshid;
Amorim, Christiani A.;
Askari, Maryam;
Zakeri, Armin;
Mousavi, Seyedeh Neda;
Kafaeinezhad, Raheleh;
Afradiasbagharani, Parivash;
Esfandyari, Sahar;
Nazari, Mahboobeh

Publication type:

Article

Increased expression of NLRP3 inflammasome components in granulosa cells and follicular fluid interleukin(IL)-1beta and IL-18 levels in fresh IVF/ICSI cycles in women with endometriosis.

Published in:

Journal of Assisted Reproduction & Genetics, 2023, v. 40, n. 1, p. 191, doi. 10.1007/s10815-022-02662-2

By:

Fonseca, Bruno M.;
Pinto, Beatriz;
Costa, Lia;
Felgueira, Eduarda;
Rebelo, Irene

Publication type:

Article

Investigation of the role of IL18, IL-1β and NLRP3 inflammasome in reducing expression of FLG-2 protein in Psoriasis vulgaris skin lesions.

Published in:

Biotechnic & Histochemistry, 2022, v. 97, n. 4, p. 277, doi. 10.1080/10520295.2021.1954692

By:

Akhlaghi, Maedeh;
Karrabi, Maryam;
Atabti, Hadi;
Raoofi, Amir;
Mousavi Khaneghah, Amin

Publication type:

Article

Cholesterol crystals activate NLRP3 inflammasomes and promote gallstone formation by increasing mucin secretion.

Published in:

Biotechnic & Histochemistry, 2022, v. 97, n. 7, p. 546, doi. 10.1080/10520295.2022.2036813

By:

You-Ming Lei;
Ran Yan;
Yue-Dong Gao;
Hong-Ju Yang;
Hong-Yan Bi;
Yong-Qing Duan

Publication type:

Article

NLRP3 as a therapeutic target in cyclophosphamide-associated toxicities.

Published in:

Molecular Biology Reports, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s11033-025-10479-2

By:

Srirangan, Prathap;
Shyam, Mukul;
Radhakrishnan, Vidya;
Prince, Sabina Evan

Publication type:

Article

The hepatoprotective effect of sodium butyrate on hepatic inflammatory injury mediated by the NLRP3 inflammatory pathway in subchronic fluoride-exposed mice.

Published in:

Molecular Biology Reports, 2024, v. 51, n. 1, p. 1, doi. 10.1007/s11033-024-09926-3

By:

Li, Wen;
Ma, Zhiyu;
Su, Cuijing;
Liu, Funing;
Yan, Nan;
Duan, Xiaoxu;
Sun, Zhenxiang;
Wang, Hongbo;
Ma, Yufei;
Wang, Zhengdong;
Ren, Fu

Publication type:

Article

Quetiapine attenuates cadmium neurotoxicity by suppressing oxidative stress, inflammation, and pyroptosis.

Published in:

Molecular Biology Reports, 2024, v. 51, n. 1, p. 1, doi. 10.1007/s11033-024-09558-7

By:

Althagafy, Hanan S.;
Harakeh, Steve;
Azhari, Sheren A.;
Farsi, Reem M.;
Al-Abbas, Nouf S.;
Shaer, Nehad A.;
Sharawi, Zeina W.;
Almohaimeed, Hailah M.;
Hassanein, Emad H. M.

Publication type:

Article

Safranal exerts a neuroprotective effect on Parkinson's disease with suppression of NLRP3 inflammation activation.

Published in:

Molecular Biology Reports, 2024, v. 51, n. 1, p. 1, doi. 10.1007/s11033-024-09537-y

By:

Yang, Wenping;
Wei, Yongyue;
Sun, Jin;
Yao, Caixia;
Ai, Fen;
Ding, Haixia

Publication type:

Article

NLRP3 inflammasome in cardiovascular diseases: Pathophysiological and pharmacological implications.

Published in:

Medicinal Research Reviews, 2021, v. 41, n. 4, p. 1890, doi. 10.1002/med.21781

By:

Pellegrini, Carolina;
Martelli, Alma;
Antonioli, Luca;
Fornai, Matteo;
Blandizzi, Corrado;
Calderone, Vincenzo

Publication type:

Article

DPP-4 inhibition by linagliptin prevents cardiac dysfunction and inflammation by targeting the Nlrp3/ASC inflammasome.

Published in:

Basic Research in Cardiology, 2019, v. 114, n. 5, p. N.PAG, doi. 10.1007/s00395-019-0743-0

By:

Birnbaum, Yochai;
Tran, Dat;
Bajaj, Mandeep;
Ye, Yumei

Publication type:

Article

The NLRP3 inflammasome in allergic diseases: mechanisms and therapeutic implications.

Published in:

Clinical & Experimental Medicine, 2024, v. 24, n. 1, p. 1, doi. 10.1007/s10238-024-01492-z

By:

Zhou, Huiqin;
Wang, Li;
Lv, Wei;
Yu, Hongmeng

Publication type:

Article

Protein targeting by the itaconate family in immunity and inflammation.

Published in:

Biochemical Journal, 2022, v. 479, n. 24, p. 2499, doi. 10.1042/BCJ20220364

By:

Day, Emily A.;
O'Neill, Luke A. J.

Publication type:

Article

Immunothrombosis and the molecular control of tissue factor by pyroptosis: prospects for new anticoagulants.

Published in:

Biochemical Journal, 2022, v. 479, n. 6, p. 731, doi. 10.1042/BCJ20210522

By:

Ryan, Tristram A. J.;
Preston, Roger J. S.;
O'Neill, Luke A. J.

Publication type:

Article

The NLRP3 Inflammasome-Independent IL-18 Elevation Induced by Candida Albicans Cell Wall.

Published in:

Trends in Sciences, 2023, v. 20, n. 11, p. 1, doi. 10.48048/tis.2023.6888

By:

Muharram, Aries;
Sulistyani, Erna;
Triwayuni, Iin Eliana;
Rahayu, Yani Corvianindya;
Mastutik, Gondo

Publication type:

Article

The pro-inflammatory effect of Staphylokinase contributes to community-associated Staphylococcus aureus pneumonia.

Published in:

Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-03571-x

By:

Wang, Yanan;
Zhao, Na;
Jian, Ying;
Liu, Yao;
Zhao, Lin;
He, Lei;
Liu, Qian;
Li, Min

Publication type:

Article

NLRP3 inflammasome as a novel target for cystic fibrosis treatment.

Published in:

Bulletin of the National Research Centre, 2023, v. 47, n. 1, p. 1, doi. 10.1186/s42269-023-01005-0

By:

Atalay, Merve;
Şen, Başak;
Dayangaç Erden, Didem

Publication type:

Article

粉葛水提物对 2 型糖尿病 db/db 小鼠胰岛细胞炎症损伤的改善作用及其机制.

Published in:

Food Research & Development, 2024, v. 45, n. 1, p. 34, doi. 10.12161/j.issn.1005⁃6521.2024.01.005

By:

朱洪杨;
刘烨;
容子玲;
李玉婷;
常诗瑶;
刘玉晖

Publication type:

Article

Reactive oxygen species-mediated activation of NLRP3 inflammasome associated with pyroptosis in Het-1A cells induced by the co-exposure of nitrosamines.

Published in:

Journal of Applied Toxicology, 2022, v. 42, n. 10, p. 1651, doi. 10.1002/jat.4332

By:

Qiwei Liu;
Chao Zhao;
Jingjing Zhou;
Hu Zhang;
Ying Zhang;
Shizhi Wang;
Yuepu Pu;
Lihong Yin

Publication type:

Article

α‐Mangostin protects lipopolysaccharide‐stimulated nucleus pulposus cells against NLRP3 inflammasome‐mediated apoptosis via the NF‐κB pathway.

Published in:

Journal of Applied Toxicology, 2022, v. 42, n. 9, p. 1467, doi. 10.1002/jat.4306

By:

Chen, Jingyang;
Bian, Meiru;
Pan, Lingxiao;
Yang, Hanshi

Publication type:

Article