Works matching DE "NILOTINIB"

Results: 558

A preclinical study demonstrating the efficacy of nilotinib in inhibiting the growth of pediatric high-grade glioma.

Published in:

Journal of Neuro-Oncology, 2015, v. 122, n. 3, p. 471, doi. 10.1007/s11060-015-1744-y

By:

Au, Karolyn;
Singh, Sanjay;
Burrell, Kelly;
Sabha, Nesrin;
Hawkins, Cynthia;
Huang, Annie;
Zadeh, Gelareh

Publication type:

Article

Efficacy and selectivity of nilotinib on NF1-associated tumors in vitro.

Published in:

Journal of Neuro-Oncology, 2014, v. 116, n. 2, p. 231, doi. 10.1007/s11060-013-1295-z

By:

Jiang, Wei;
Schnabel, Claudia;
Spyra, Melanie;
Mautner, Victor-F;
Friedrich, Reinhard;
Hagel, Christian;
Manley, Paul;
Kluwe, Lan

Publication type:

Article

Hepatoprotective effect of the tyrosine kinase inhibitor nilotinib against cyclosporine‐A induced liver injury in rats through blocking the Bax/Cytochrome C/caspase‐3 apoptotic signaling pathway.

Published in:

Journal of Biochemical & Molecular Toxicology, 2021, v. 35, n. 6, p. 1, doi. 10.1002/jbt.22764

By:

Serrya, Marwa S.;
Nader, Manar A.;
Abdelmageed, Marwa E.

Publication type:

Article

New-generation tyrosine kinase inhibitor-associated asymptomatic cerebrovascular stenosis: two illustrative cases.

Published in:

2022

By:

Hirayama, Akihiro;
Sorimachi, Takatoshi;
Yokota, Kazuma;
Shigematsu, Hideaki;
Srivatanakul, Kittipong;
Matsumae, Mitsunori

Publication type:

Case Study

Evaluation of Time to Onset and Outcome of Cardiac Adverse Events Associated with Nilotinib using Post-Marketing Surveillance.

Published in:

Oncology, 2023, v. 101, n. 12, p. 799, doi. 10.1159/000533325

By:

Kanbayashi, Yuko;
Kojima, Asuka;
Wakabayashi, Haruka;
Shimizu, Tadashi;
Uchida, Mayako

Publication type:

Article

Nilotinib in Combination with Carboplatin and Paclitaxel Is a Candidate for Ovarian Cancer Treatment.

Published in:

Oncology, 2014, v. 87, n. 4, p. 232, doi. 10.1159/000363656

By:

Weigel, Marion T.;
Rath, Katrin;
Alkatout, Ibrahim;
Wenners, Antonia S.;
Schem, Christian;
Maass, Nicolai;
Jonat, Walter;
Mundhenke, Christoph

Publication type:

Article

Preclinical Evaluation of a Novel Small Molecule Inhibitor of LIM Kinases (LIMK) CEL_Amide in Philadelphia-Chromosome Positive (BCR::ABL+) Acute Lymphoblastic Leukemia (ALL).

Published in:

Journal of Clinical Medicine, 2022, v. 11, n. 22, p. 6761, doi. 10.3390/jcm11226761

By:

Berrou, Jeannig;
Dupont, Mélanie;
Djamai, Hanane;
Adicéam, Emilie;
Parietti, Véronique;
Kaci, Anna;
Clappier, Emmanuelle;
Cayuela, Jean-Michel;
Baruchel, André;
Paublant, Fabrice;
Prudent, Renaud;
Ghysdael, Jacques;
Gardin, Claude;
Dombret, Hervé;
Braun, Thorsten

Publication type:

Article

Chronic Myeloid Leukemia and Pregnancy: When Dreams Meet Reality. State of the Art, Management and Outcome of 41 Cases, Nilotinib Placental Transfer.

Published in:

Journal of Clinical Medicine, 2022, v. 11, n. 7, p. 1801, doi. 10.3390/jcm11071801

By:

Abruzzese, Elisabetta;
Aureli, Stefano;
Bondanini, Francesco;
Ciccarone, Mariavita;
Cortis, Elisabetta;
Di Paolo, Antonello;
Fabiani, Cristina;
Galimberti, Sara;
Malagola, Michele;
Malato, Alessandra;
Martino, Bruno;
Trawinska, Malgorzata Monika;
Russo, Domenico;
de Fabritiis, Paolo

Publication type:

Article

Combined Inhibition of Bcl2 and Bcr-Abl1 Exercises Anti-Leukemia Activity but Does Not Eradicate the Primitive Leukemic Cells.

Published in:

Journal of Clinical Medicine, 2021, v. 10, n. 23, p. 5606, doi. 10.3390/jcm10235606

By:

Massimino, Michele;
Vigneri, Paolo;
Stella, Stefania;
Tirrò, Elena;
Pennisi, Maria Stella;
Parrinello, Laura Nunziatina;
Vetro, Calogero;
Manzella, Livia;
Stagno, Fabio;
Di Raimondo, Francesco

Publication type:

Article

Dose Optimization of Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia: A New Therapeutic Challenge.

Published in:

Journal of Clinical Medicine, 2021, v. 10, n. 3, p. 515, doi. 10.3390/jcm10030515

By:

Iurlo, Alessandra;
Cattaneo, Daniele;
Bucelli, Cristina;
Breccia, Massimo;
Russo, Domenico

Publication type:

Article

Health-Related Quality of Life in Patients with Chronic Myeloid Leukemia Treated with First- Versus Second-Generation Tyrosine Kinase Inhibitors.

Published in:

Journal of Clinical Medicine, 2020, v. 9, n. 11, p. 3417, doi. 10.3390/jcm9113417

By:

Shacham Abulafia, Adi;
Shemesh, Sivan;
Rosenmann, Lena;
Berger, Tamar;
Leader, Avi;
Sharf, Giora;
Raanani, Pia;
Rozovski, Uri

Publication type:

Article

Current Treatment Options for Chronic Myeloid Leukemia Patients Failing Second-Generation Tyrosine Kinase Inhibitors.

Published in:

Journal of Clinical Medicine, 2020, v. 9, n. 7, p. 2251, doi. 10.3390/jcm9072251

By:

García-Gutiérrez, Valentín;
Hernández-Boluda, Juan Carlos

Publication type:

Article

Association of Nilotinib With Cardiovascular Diseases in Patients With Chronic Myelogenous Leukemia: A National Population-Based Cohort Study.

Published in:

Oncologist, 2024, v. 29, n. 1, p. e81, doi. 10.1093/oncolo/oyad225

By:

Huang, Cih-En;
Lee, Kuan-Der;
Chang, Jung-Jung;
Tzeng, Huey-En;
Huang, Shih-Hao;
Yu, Lennex Hsueh-Lin;
Chen, Min-Chi

Publication type:

Article

Tyrosine Kinase Inhibitors and Vascular Adverse Events in Patients with Chronic Myeloid Leukemia: A Population‐Based, Propensity Score‐Matched Cohort Study.

Published in:

Oncologist, 2021, v. 26, n. 11, p. 974, doi. 10.1002/onco.13944

By:

Chen, Mei‐Tsen;
Huang, Shih‐Tsung;
Lin, Chih‐Wan;
Ko, Bor‐Sheng;
Chen, Wen‐Jone;
Huang, Huai‐Hsuan;
Hsiao, Fei‐Yuan

Publication type:

Article

Planned Pregnancy in Female Patients with Chronic Myeloid Leukemia Receiving Tyrosine Kinase Inhibitor Therapy.

Published in:

Oncologist, 2019, v. 24, n. 11, p. e1141, doi. 10.1634/theoncologist.2019-0109

By:

Dou, Xuelin;
Qin, Yazhen;
Huang, Xiaojun;
Jiang, Qian

Publication type:

Article

U.S. Food and Drug Administration Benefit‐Risk Assessment of Nilotinib Treatment Discontinuation in Patients with Chronic Phase Chronic Myeloid Leukemia in a Sustained Molecular Remission.

Published in:

Oncologist, 2019, v. 24, n. 5, p. e188, doi. 10.1634/theoncologist.2018-0759

By:

Pulte, E. Dianne;
Wroblewski, Tanya;
Bloomquist, Erik;
Tang, Shenghui;
Farrell, Ann;
Deisseroth, Albert;
McKee, Amy E.;
Pazdur, Richard

Publication type:

Article

Evaluating the Strength of the Association Between Industry Payments and Prescribing Practices in Oncology.

Published in:

Oncologist, 2019, v. 24, n. 5, p. 632, doi. 10.1634/theoncologist.2018-0423

By:

Mitchell, Aaron P.;
Winn, Aaron N.;
Lund, Jennifer L.;
Dusetzina, Stacie B.

Publication type:

Article

Fertility Preservation in Leukemia.

Published in:

Oncologist, 2018, v. 23, n. 6, p. 645, doi. 10.1634/theoncologist.2017-0635

By:

Blumenfeld, Zeev

Publication type:

Article

Successful Ovarian Stimulation for Fertility Preservation in a Patient with Chronic Myeloid Leukemia: Switch from Nilotinib to Interferon‐α.

Published in:

Oncologist, 2018, v. 23, n. 6, p. 719, doi. 10.1634/theoncologist.2017-0381

By:

Gazdaru, Smaranda;
Perey, Lucien;
Rosselet, Anne;
Mathevet, Patrice;
Chalandon, Yves;
Vulliemoz, Nicolas

Publication type:

Article

p53 Gene (NY-CO-13) Levels in Patients with Chronic Myeloid Leukemia: The Role of Imatinib and Nilotinib.

Published in:

Diseases, 2018, v. 6, n. 1, p. 13, doi. 10.3390/diseases6010013

By:

Al-kuraishy, Hayder M.;
Al-Gareeb, Ali I.;
Al-Buhadilly, Ali K.

Publication type:

Article

EFFICACY OF NILOTINIB IN PATIENTS WITH CHRONIC MYELOID LEUKEMIA.

Published in:

Journal of University Medical & Dental College, 2019, v. 10, n. 4, p. 1, doi. 10.37723/jumdc.v10i4.78

By:

Ali, Sajid;
Mehmood, Tahir;
Bano, Kausar;
Akram, Muhammad;
Khan, Muhammad Imran;
Fatima, Tehreem

Publication type:

Article

A DNA Biosensor Based on a Raspberry‐like Hierarchical Nano‐structure for the Determination of the Anticancer Drug Nilotinib.

Published in:

ChemistryOpen, 2022, v. 11, n. 3, p. 1, doi. 10.1002/open.202100261

By:

Moarefdoust, Mohammad Mehdi;
Jahani, Shohreh;
Moradalizadeh, Mehran;
Motaghi, Mohammad Mehdi;
Foroughi, Mohammad Mehdi

Publication type:

Article

Inhibition of eukaryotic initiation factor 3B suppresses proliferation and promotes apoptosis of chronic myeloid leukemia cells.

Published in:

Advances in Clinical & Experimental Medicine, 2019, v. 28, n. 12, p. 1639, doi. 10.17219/acem/110323

By:

Laiquan Huang;
Kun He;
Jianxin Wang;
Jiawei Yan;
Yizhi Jiang;
Zhongling Wei;
Jun Zhang;
Guangxi Li;
Lili Sheng

Publication type:

Article

Medication-induced osteonecrosis of the jaw: a review of cases from the Food and Drug Administration Adverse Event Reporting System (FAERS).

Published in:

BMC Pharmacology & Toxicology, 2023, v. 24, n. 1, p. 1, doi. 10.1186/s40360-023-00657-y

By:

Ahdi, Hardeep S.;
Wichelmann, Thomas Adam;
Pandravada, Sasirekha;
Ehrenpreis, Eli D.

Publication type:

Article

Pharmacokinetics, Bioequivalence, and Safety Studies of a Generic Selective Tyrosine Kinase Inhibitor Nilotinib Capsule Versus a Branded Product in Healthy Chinese Volunteers.

Published in:

Clinical Pharmacology in Drug Development, 2022, v. 11, n. 10, p. 1233, doi. 10.1002/cpdd.1148

By:

Wang, Meng;
Zhu, Yifang;
Huang, Ming;
Wang, Hao;
Zhou, Wenjia;
Lu, Dan;
Zhang, Quanying

Publication type:

Article

A Randomized, Double‐Blind, Placebo‐ and Positive‐Controlled, Three‐Way Crossover Study in Healthy Participants to Investigate the Effect of Savolitinib on the QTc Interval.

Published in:

Clinical Pharmacology in Drug Development, 2021, v. 10, n. 5, p. 521, doi. 10.1002/cpdd.896

By:

Sahota, Tarjinder;
Dota, Corina D.;
Vik, Torbjörn;
Yan, Weili;
Verheijen, Remy B.;
Walker, Stephen;
Li, Yan;
Goldwater, Ronald;
Ghiorghiu, Dana;
Mellemgaard, Anders;
Ahmed, Ghada F.

Publication type:

Article

A retrospective study of the prescribing and outcomes of tyrosine kinase inhibitors in chronic myeloid leukaemia over a period of more than 10 years.

Published in:

Journal of Clinical Pharmacy & Therapeutics, 2015, v. 40, n. 4, p. 391, doi. 10.1111/jcpt.12273

By:

Lang, A.‐S.;
Mounier, M.;
Roques, M.;
Chretien, M. L.;
Boulin, M.

Publication type:

Article

Cost-effectiveness of tyrosine kinase inhibitor treatment strategies for chronic myeloid leukemia in South Africa.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2024.1511603

By:

Woudberg, Rochelle;
Sinanovic, Edina

Publication type:

Article

Discontinuation of Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia With Losing Major Molecular Response as a Definition for Molecular Relapse: A Systematic Review and Meta-Analysis.

Published in:

Frontiers in Oncology, 2019, p. N.PAG, doi. 10.3389/fonc.2019.00372

By:

Chen, Kang-kang;
Du, Tai-feng;
Xiong, Pei-sheng;
Fan, Guan-hua;
Yang, Wei

Publication type:

Article

Oroxylin a Inhibits the Protection of Bone Marrow Microenvironment on CML Cells Through CXCL12/CXCR4/P-gp Signaling Pathway.

Published in:

Frontiers in Oncology, 2019, p. N.PAG, doi. 10.3389/fonc.2019.00188

By:

Cao, Hanbo;
Li, Wenjun;
Zhou, Yizhou;
Tan, Renxiang;
Yang, Yue;
Zhou, You;
Guo, Qinglong;
Zhao, Li

Publication type:

Article

In-depth characterization of NK cell markers from CML patients who discontinued tyrosine kinase inhibitor therapy.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1241600

By:

Sanchez, María Belén;
Vasconcelos Cordoba, Bianca;
Pavlovsky, Carolina;
Moiraghi, Beatriz;
Varela, Ana;
Custidiano, Rosario;
Fernandez, Isolda;
Freitas, María Josefina;
Ventriglia, María Verónica;
Bendek, Georgina;
Mariano, Romina;
Mela Osorio, María José;
Arturo Pavlovsky, Miguel;
García de Labanca, Ana;
Foncuberta, Cecilia;
Giere, Isabel;
Vera, Masiel;
Juni, Mariana;
Mordoh, José;
Sanchez Avalos, Julio Cesar

Publication type:

Article

Development of myasthenia gravis in a patient with chronic myeloid leukemia during treatment with nilotinib.

Published in:

2014

By:

Sanford, David;
MacDonald, Maria;
Nicolle, Michael;
Xenocostas, Anargyros

Publication type:

Case Study

Multiple squamous cell carcinomas following introduction of nilotinib.

Published in:

Clinical & Experimental Dermatology, 2014, v. 39, n. 7, p. 791, doi. 10.1111/ced.12388

By:

Peters, P.;
Rabbolini, D.;
Sinnya, S.;
Khosrotehrani, K.;
Wagner, G.

Publication type:

Article

Anti-Angiogenic Tyrosine Kinase Inhibitors and Reversible Posterior Leukoencephalopathy Syndrome: Could Hypomagnesaemia Be the Trigger?

Published in:

2017

By:

Shah, Rashmi;
Shah, Rashmi R

Publication type:

journal article

Chemotherapy a Last Resort for Cancer Treatment.

Published in:

International Journal of Pharmacy & Life Sciences, 2018, v. 9, n. 2, p. 32

By:

Kulkarni, Sweta

Publication type:

Article

Effects of imatinib and nilotinib on the whole transcriptome of cultured murine osteoblasts.

Published in:

Molecular Medicine Reports, 2016, v. 14, n. 3, p. 2025, doi. 10.3892/mmr.2016.5459

By:

KIRSCHNER, GYÖNGYI;
BALLA, BERNADETT;
HORVÁTH, PÉTER;
KÖVESDI, ANDREA;
LAKATOS, GERGELY;
TAKÁCS, ISTVÁN;
NAGY, ZSOLT;
TÓBIÁS, BÁLINT;
ÁRVAI, KRISTÓF;
KÓSA, JÁNOS PÁL;
LAKATOS, PÉTER

Publication type:

Article

Ramadan Fasting in a Patient with Chronic Myeloid Leukemia Receiving Nilotinib as Upfront.

Published in:

Case Reports in Oncology, 2020, v. 13, n. 2, p. 664, doi. 10.1159/000507508

By:

Al-Dubai, Husam N.;
Yassin, Mohammed A.;
Abdulla, Mohammed A.;
Aldapt, Mahmood S.;
Ghassoub, Rola S.

Publication type:

Article

Antifibrotic Effect of Combination of Nilotinib and Stem Cell-Conditioned Media on CCl4-Induced Liver Fibrosis.

Published in:

Stem Cells International, 2020, p. 1, doi. 10.1155/2020/6574010

By:

Shiha, Gamal;
Nabil, Ahmed;
Lotfy, Ahmed;
Soliman, Reham;
Hassan, Ayman A.;
Ali, Islam S.;
Gad, Doaa F.;
Zahran, Faten

Publication type:

Article

Imaging the intracellular distribution of tyrosine kinase inhibitors in living cells with quantitative hyperspectral stimulated Raman scattering.

Published in:

Nature Chemistry, 2014, v. 6, n. 7, p. 614, doi. 10.1038/nchem.1961

By:

Fu, Dan;
Zhou, Jing;
Zhu, Wenjing Suzanne;
Manley, Paul W.;
Wang, Y. Karen;
Hood, Tami;
Wylie, Andrew;
Xie, X. Sunney

Publication type:

Article

Examining the Early Period Effect of Nilotinib on Hearing: An Experimental Study.

Published in:

Journal of International Advanced Otology, 2020, v. 16, n. 2, p. 77, doi. 10.5152/iao.2019.5908

By:

Bora, Adem;
Durmuş, Kasım;
Terzi, Hatice;
Altuntaş, Emine Elif

Publication type:

Article

Examining the Early Period Effect of Nilotinib on Hearing: An Experimental Study.

Published in:

Journal of International Advanced Otology, 2020, v. 16, n. 1, p. 77, doi. 10.5152/iao.2019.5908

By:

Bora, Adem;
Durmuş, Kasım;
Terzi, Hatice;
Altuntaş, Emine Elif

Publication type:

Article

Response rate of imatinib among patients with chronic myeloid leukemia in Thailand: A retrospective study.

Published in:

Thai Journal of Pharmaceutical Sciences, 2024, v. 48, n. 1, p. 1

By:

Yodsurang, Natthawat;
Niamhun, Narawadee;
Rattanathammethee, Thanawat;
Sirichanchuen, Buntitabhon

Publication type:

Article

Dasatinib inhibits coated-platelet generation in patients with chronic myeloid leukemia.

Published in:

Platelets, 2019, v. 30, n. 7, p. 836, doi. 10.1080/09537104.2018.1501470

By:

Mezei, Gabriella;
Debreceni, Ildiko Beke;
Kerenyi, Adrienne;
Remenyi, Gyula;
Szasz, Robert;
Illes, Arpad;
Kappelmayer, Janos;
Batar, Peter

Publication type:

Article

Second-generation antihistamines: a study of poisoning in children.

Published in:

Clinical Toxicology (15563650), 2020, v. 58, n. 4, p. 275, doi. 10.1080/15563650.2019.1634812

By:

Verdu, Eva;
Blanc-Brisset, Ingrid;
Meyer, Géraldine;
Le Roux, Gaël;
Bruneau, Chloé;
Deguigne, Marie

Publication type:

Article

A Score to Predict the Clinical Usefulness of Therapeutic Drug Monitoring: Application to Oral Molecular Targeted Therapies in Cancer.

Published in:

Clinical Pharmacology & Therapeutics, 2024, v. 116, n. 3, p. 678, doi. 10.1002/cpt.3193

By:

Géraud, Arthur;
Combarel, David;
Funck‐Brentano, Christian;
Beaulieu, Quentin;
Zahr, Noël;
Broutin, Sophie;
Spano, Jean‐Philippe;
Massard, Christophe;
Besse, Benjamin;
Gougis, Paul

Publication type:

Article

Physicians' attitude towards selection of second line therapy with nilotinib and dasatinib in chronic myeloid leukemia patients.

Published in:

2017

By:

Breccia, Massimo;
Baccarani, Michele;
Rosti, Gianantonio;
Cottone, Francesco;
Cannella, Laura;
Guilhot, François;
Vignetti, Marco;
Efficace, Fabio

Publication type:

Letter

A novel imatinib-upregulated long noncoding RNA plays a critical role in inhibition of tumor growth induced by Abl oncogenes.

Published in:

Molecular Cancer, 2022, v. 21, n. 1, p. 1, doi. 10.1186/s12943-021-01478-5

By:

Ma, Yun;
Guo, Guijie;
Li, Tingting;
Wen, Faxin;
Yang, Jianling;
Chen, Biao;
Wang, Xuefei;
Chen, Ji-Long

Publication type:

Article

Nilotinib population pharmacokinetics and exposure-response analysis in patients with imatinib-resistant or -intolerant chronic myeloid leukemia.

Published in:

European Journal of Clinical Pharmacology, 2013, v. 69, n. 4, p. 813, doi. 10.1007/s00228-012-1385-4

By:

Giles, Francis;
Yin, Ophelia;
Sallas, William;
Coutre, Philipp;
Woodman, Richard;
Ottmann, Oliver;
Baccarani, Michele;
Kantarjian, Hagop

Publication type:

Article

Pharmacokinetic profile of novel reduced-dose Danziten™ (nilotinib tablets) versus Tasigna® (nilotinib capsules): in vivo bioequivalence and population pharmacokinetic analysis.

Published in:

Cancer Chemotherapy & Pharmacology, 2025, v. 95, n. 1, p. 1, doi. 10.1007/s00280-025-04777-6

By:

Mauro, Michael;
Radich, Jerald;
Jain, Paras;
Sequeira, David;
Bellanti, Francesco;
Douer, Dan

Publication type:

Article

Are novel oral oncolytics underdosed in obese patients?

Published in:

Cancer Chemotherapy & Pharmacology, 2024, v. 93, n. 2, p. 129, doi. 10.1007/s00280-023-04601-z

By:

Lin, Lishi;
van der Meer, Ellen K. O.;
Steeghs, Neeltje;
Beijnen, Jos H.;
Huitema, Alwin D. R.

Publication type:

Article