Works matching DE "NEUROFIBROMIN"

Results: 81

Genome-scale CRISPR-Cas9 knockout screening in hepatocellular carcinoma with lenvatinib resistance.

Published in:

Cell Death Discovery, 2021, v. 7, n. 1, p. 1, doi. 10.1038/s41420-021-00747-y

By:

Lu, Yonggang;
Shen, Haoming;
Huang, Wenjie;
He, Sha;
Chen, Jianlin;
Zhang, Di;
Shen, Yongqi;
Sun, Yifan

Publication type:

Article

A novel mutation of the FAT2 gene in spinal meningioma.

Published in:

Oncology Letters, 2016, v. 12, n. 5, p. 3393, doi. 10.3892/ol.2016.5063

By:

GENSHU TATE;
KOJI KISHIMOTO;
TOSHIYUKI MITSUYA

Publication type:

Article

Atypical neurofibromatosis type 1 with unilateral limb hypertrophy mimicking overgrowth syndrome.

Published in:

Clinical & Experimental Dermatology, 2017, v. 42, n. 7, p. 763, doi. 10.1111/ced.13154

By:

Tripolszki, K.;
Farkas, K.;
Sulák, A.;
Szolnoky, G.;
Duga, B.;
Melegh, B.;
Knox, R. G.;
Parker, V. E. R.;
Semple, R. K.;
Kemény, L.;
Széll, M.;
Nagy, N.

Publication type:

Article

Accurate Classification of NF1 Gene Variants in 84 Italian Patients with Neurofibromatosis Type 1.

Published in:

Genes, 2018, v. 9, n. 4, p. 216, doi. 10.3390/genes9040216

By:

Stella, Alessandro;
Lastella, Patrizia;
Loconte, Daria Carmela;
Bukvic, Nenad;
Varvara, Dora;
Patruno, Margherita;
Bagnulo, Rosanna;
Lovaglio, Rosaura;
Bartolomeo, Nicola;
Serio, Gabriella;
Resta, Nicoletta

Publication type:

Article

Neurofibromin haploinsufficiency results in altered spermatogenesis in a mouse model of neurofibromatosis type 1.

Published in:

PLoS ONE, 2018, v. 13, n. 12, p. 1, doi. 10.1371/journal.pone.0208835

By:

Chohan, Harleen;
Esfandiarei, Mitra;
Arman, Darian;
Van Raamsdonk, Catherine D.;
van Breemen, Cornelis;
Friedman, Jan M.;
Jett, Kimberly A.

Publication type:

Article

Cutaneous manifestations in neurofibromatosis type 1.

Published in:

Clinica Terapeutica, 2020, v. 171, n. 5, p. e371, doi. 10.7417/CT.2020.2242

By:

Miraglia, E.;
Moliterni, E.;
Iacovino, C.;
Roberti, V.;
Laghi, A.;
Moramarco, A.;
Giustini, S.

Publication type:

Article

Asfotase-α improves bone growth, mineralization and strength in mouse models of neurofibromatosis type-1.

Published in:

Nature Medicine, 2014, v. 20, n. 8, p. 904, doi. 10.1038/nm.3583

By:

de la Croix Ndong, Jean;
Makowski, Alexander J;
Uppuganti, Sasidhar;
Vignaux, Guillaume;
Ono, Koichiro;
Perrien, Daniel S;
Joubert, Simon;
Baglio, Serena R;
Granchi, Donatella;
Stevenson, David A;
Rios, Jonathan J;
Nyman, Jeffry S;
Elefteriou, Florent

Publication type:

Article

Exome sequencing identifies recurrent mutations in NF1 and RASopathy genes in sun-exposed melanomas.

Published in:

Nature Genetics, 2015, v. 47, n. 9, p. 996, doi. 10.1038/ng.3361

By:

Lifton, Richard P;
Cheng, Elaine;
Halaban, Ruth;
McCusker, James P;
Ma, Shuangge;
Sznol, Mario;
Krauthammer, Michael;
Serin, Merdan;
Evans, Perry;
Mane, Shrikant;
Bacchiocchi, Antonella;
Pornputtapong, Natapol;
Narayan, Deepak;
Kluger, Harriet M;
Bosenberg, Marcus;
Kong, Yong;
Wu, Cen;
Ariyan, Stephan;
Schlessinger, Joseph;
Straub, Robert

Publication type:

Article

Modulation of Ras signaling alters the toxicity of hydroquinone, a benzene metabolite and component of cigarette smoke.

Published in:

BMC Cancer, 2014, v. 14, n. 1, p. 1, doi. 10.1186/1471-2407-14-6

By:

North, Matthew;
Shuga, Joe;
Fromowitz, Michele;
Loguinov, Alexandre;
Shannon, Kevin;
Luoping Zhang;
Smith, Martyn T.;
Vulpe, Chris D.

Publication type:

Article

Down-regulated Six2 by knockdown of neurofibromin results in apoptosis of metanephric mesenchyme cells in vitro.

Published in:

Molecular & Cellular Biochemistry, 2014, v. 390, n. 1/2, p. 205, doi. 10.1007/s11010-014-1971-0

By:

Zhou, Puhui;
Chen, Tielin;
Fang, Yin;
Wang, Honglian;
Li, Mi;
Ma, Pengpeng;
He, Lu;
Li, Qianyin;
Liu, Tianming;
Yang, Xianggui;
Nie, Fang;
Wang, Xiaoyan;
Yuan, Yue;
Zhou, Li;
Peng, Rui;
Liu, Zhicheng;
Zhou, Qin

Publication type:

Article

Neurofibromin specific antibody differentiates malignant peripheral nerve sheath tumors (MPNST) from other spindle cell neoplasms.

Published in:

Acta Neuropathologica, 2014, v. 127, n. 4, p. 565, doi. 10.1007/s00401-014-1246-6

By:

Reuss, David;
Habel, Antje;
Hagenlocher, Christian;
Mucha, Jana;
Ackermann, Ulrike;
Tessmer, Claudia;
Meyer, Jochen;
Capper, David;
Moldenhauer, Gerhard;
Mautner, Victor;
Frappart, Pierre-Olivier;
Schittenhelm, Jens;
Hartmann, Christian;
Hagel, Christian;
Katenkamp, Kathrin;
Petersen, Iver;
Mechtersheimer, Gunhild;
Deimling, Andreas

Publication type:

Article

Neuregulin-1 overexpression and Trp53 haploinsufficiency cooperatively promote de novo malignant peripheral nerve sheath tumor pathogenesis.

Published in:

Acta Neuropathologica, 2014, v. 127, n. 4, p. 573, doi. 10.1007/s00401-013-1209-3

By:

Brosius, Stephanie;
Turk, Amy;
Byer, Stephanie;
Brossier, Nicole;
Kohli, Latika;
Whitmire, Amber;
Mikhail, Fady;
Roth, Kevin;
Carroll, Steven

Publication type:

Article

Defective nuclear import of Tpr in Progeria reflects the Ran sensitivity of large cargo transport.

Published in:

Journal of Cell Biology, 2013, v. 201, n. 4, p. 541, doi. 10.1083/jcb.201212117

By:

Snow, Chelsi J.;
Dar, Ashraf;
Dutta, Anindya;
Kehlenbach, Ralph H.;
Paschal, Bryce M.

Publication type:

Article

Primary leiomyosarcoma of the psoas in a patient with Neurofibromatosis type 1.

Published in:

2018

By:

Mansouri, Siham;
Mai, Sara;
Houssaini, Asmaa Sqalli;
Hassam, Badr;
Ismaili, Nadia

Publication type:

Case Study

Modeling mesothelioma utilizing human mesothelial cells reveals involvement of phospholipase-C beta 4 in YAP-active mesothelioma cell proliferation.

Published in:

Carcinogenesis, 2016, v. 37, n. 11, p. 1098, doi. 10.1093/carcin/bgw084

By:

Tatsuo Kakiuchi;
Taishi Takahara;
Yumiko Kasugai;
Kotaro Arita;
Noriaki Yoshida;
Kennosuke Karube;
Miyuki Suguro;
Keitaro Matsuo;
Hayao Nakanishi;
Tohru Kiyono;
Shigeo Nakamura;
Hirotaka Osada;
Yoshitaka Sekido;
Masao Seto;
Shinobu Tsuzuki

Publication type:

Article

Double NF1 Inactivation Affects Adrenocortical Function in NF1Prx1 Mice and a Human Patient.

Published in:

PLoS ONE, 2015, v. 10, n. 3, p. 1, doi. 10.1371/journal.pone.0119030

By:

Kobus, Karolina;
Hartl, Daniela;
Ott, Claus Eric;
Osswald, Monika;
Huebner, Angela;
von der Hagen, Maja;
Emmerich, Denise;
Kühnisch, Jirko;
Morreau, Hans;
Hes, Frederik J.;
Mautner, Victor F.;
Harder, Anja;
Tinschert, Sigrid;
Mundlos, Stefan;
Kolanczyk, Mateusz

Publication type:

Article

Genetic Interactions between Neurofibromin and Endothelin Receptor B in Mice.

Published in:

PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0059931

By:

Deo, Mugdha;
Huang, Jenny Li-Ying;
Van Raamsdonk, Catherine D.

Publication type:

Article

Sensitivity of Malignant Peripheral Nerve Sheath Tumor Cells to TRAIL Is Augmented by Loss of NF1 through Modulation of MYC/MAD and Is Potentiated by Curcumin through Induction of ROS.

Published in:

PLoS ONE, 2013, v. 8, n. 2, p. 1, doi. 10.1371/journal.pone.0057152

By:

Reuss, David E.;
Mucha, Jana;
Hagenlocher, Christian;
Ehemann, Volker;
Kluwe, Lan;
Mautner, Victor;
von Deimling, Andreas

Publication type:

Article

Neurofibromin 1 Is a miRNA Target in Neurons.

Published in:

PLoS ONE, 2012, v. 7, n. 10, p. 1, doi. 10.1371/journal.pone.0046773

By:

Paschou, Maria;
Doxakis, Epaminondas

Publication type:

Article

Non-invasive endothelial function assessment in patients with neurofibromatosis type 1: a cross-sectional study.

Published in:

BMC Cardiovascular Disorders, 2013, v. 13, n. 1, p. 1, doi. 10.1186/1471-2261-13-18

By:

Rodrigues, Luiza O.;
Rodrigues, Luiz Oswaldo C.;
Castro, Luisa Lima;
Rezende, Nilton A.;
Ribeiro, Antonio Luiz P.

Publication type:

Article

Neurofibromin 1 Impairs Natural Killer T-Cell-Dependent Antitumor Immunity against a T-Cell Lymphoma.

Published in:

Frontiers in Immunology, 2018, p. 1, doi. 10.3389/fimmu.2017.01901

By:

Liu, Jianyun;
Gallo, Richard M.;
Khan, Masood A.;
Renukaradhya, Gourapura J.;
Brutkiewicz, Randy R.

Publication type:

Article

Polymorphism in the neurofibromin gene, Nf1, is associated with antagonistic selection on wing size and development time in Drosophila melanogaster.

Published in:

Molecular Ecology, 2013, v. 22, n. 10, p. 2716, doi. 10.1111/mec.12301

By:

Lee, Siu F.;
Eyre‐Walker, Ying Chen;
Rane, Rahul V.;
Reuter, Caroline;
Vinti, Giovanna;
Rako, Lea;
Partridge, Linda;
Hoffmann, Ary A.

Publication type:

Article

Neurofibromin regulates HCN activity in Parvalbumin-positive interneurons.

Published in:

Molecular Psychiatry, 2015, v. 20, n. 11, p. 1263, doi. 10.1038/mp.2015.154

By:

Omrani, A;
van Woerden, G M;
Elgersma, Y

Publication type:

Article

Increased risk of breast cancer in neurofibromatosis type I: current insights.

Published in:

Breast Cancer: Targets & Therapy, 2017, v. 9, p. 531, doi. 10.2147/BCTT.S111397

By:

Howell, Sacha J.;
Hockenhull, Kimberley;
Salih, Zena;
Evans, D. Gareth

Publication type:

Article

Giant thrombosed intracavernous carotid artery aneurysm presenting as Tolosa-Hunt syndrome in a patient harboring a new pathogenic neurofibromatosis type 1 mutation: a case report and review of the literature.

Published in:

Neuropsychiatric Disease & Treatment, 2014, v. 10, p. 135, doi. 10.2147/NDT.S49784

By:

Conforti, Renata;
Cirillo, Mario;
Marrone, Valeria;
Galasso, Rosario;
Capaldo, Guglielmo;
Giugliano, Teresa;
Scuotto, Assunta;
Piluso, Giulio;
Melone, Mariarosa A. B.

Publication type:

Article

Role of Neurofibromin in Modulation of Expression of the Tyrosinase-Related Protein 2 Gene1.

Published in:

Journal of Biochemistry, 1998, v. 124, n. 5, p. 992, doi. 10.1093/oxfordjournals.jbchem.a022218

By:

Suzuki, Hiroyuki;
Takahashi, Kazuhiro;
Yasumoto, Ken-ichi;
Amae, Shintaro;
Yoshizawa, Miki;
Fuse, Nobuo;
Shibahara, Shigeki

Publication type:

Article

Differential Tissue-Specific Expression of Neurofibromin Isoform mRNAs in Rat1.

Published in:

Journal of Biochemistry, 1996, v. 120, n. 5, p. 1048, doi. 10.1093/oxfordjournals.jbchem.a021498

By:

Suzuki, Hiroyuki;
Takahashi, Kazuhiro;
Yasumoto, Ken-ichi;
Fuse, Nobuo;
Shibahara, Shigeki

Publication type:

Article

Correction.

Published in:: 2017
Publication type:: Correction Notice

Hippocampal Dysregulation of Neurofibromin-Dependent Pathways Is Associated with Impaired Spatial Learning in Engrailed 2 Knock-Out Mice.

Published in:

Journal of Neuroscience, 2014, v. 34, n. 40, p. 13281, doi. 10.1523/JNEUROSCI.2894-13.2014

By:

Provenzano, Giovanni;
Pangrazzi, Luca;
Poli, Andrea;
Pernigo, Mattia;
Sgadò, Paola;
Genovesi, Sacha;
Zunino, Giulia;
Berardi, Nicoletta;
Casarosa, Simona;
Bozzi, Yuri

Publication type:

Article

Neurofibromin Is the Major Ras Inactivator in Dendritic Spines.

Published in:

Journal of Neuroscience, 2014, v. 34, n. 3, p. 776, doi. 10.1523/JNEUROSCI.3096-13.2014

By:

Oliveira, Ana F.;
Ryohei Yasuda

Publication type:

Article

Neurofibromin Mediates FAK Signaling in Confining Synapse Growth at Drosophila Neuromuscular Junctions.

Published in:

Journal of Neuroscience, 2012, v. 32, n. 47, p. 16971, doi. 10.1523/JNEUROSCI.1756-12.2012

By:

Tsai, Pei-I;
Wang, Manyu;
Kao, Hsiu-Hua;
Ying-Ju Cheng;
Walker, James A.;
Chen, Ruey-Hwa;
Cheng-Ting Chien

Publication type:

Article

Neurofibromin Modulates Adult Hippocampal Neurogenesis and Behavioral Effects of Antidepressants.

Published in:

Journal of Neuroscience, 2012, v. 32, n. 10, p. 3529, doi. 10.1523/JNEUROSCI.3469-11.2012

By:

Yun Li;
Yanjiao Li;
McKay, Rene'e M.;
Riethmacher, Dieter;
Parada, Luis F.

Publication type:

Article

Exogenous miRNA-146a Enhances the Therapeutic Efficacy of Human Mesenchymal Stem Cells by Increasing Vascular Endothelial Growth Factor Secretion in the Ischemia/Reperfusion-Injured Heart.

Published in:

Journal of Vascular Research, 2017, v. 54, n. 2, p. 100, doi. 10.1159/000461596

By:

Seo, Hyang-Hee;
Lee, Se-Yeon;
Lee, Chang Youn;
Kim, Ran;
Kim, Pilseog;
Oh, Sekyung;
Lee, Hojin;
Lee, Min Young;
Kim, Jongmin;
Kim, Lark Kyun;
Hwang, Ki-Chul;
Chang, Woochul

Publication type:

Article

A RASopathy gene commonly mutated in cancer: the neurofibromatosis type 1 tumour suppressor.

Published in:

Nature Reviews Cancer, 2015, v. 15, n. 5, p. 290, doi. 10.1038/nrc3911

By:

Ratner, Nancy;
Miller, Shyra J.

Publication type:

Article

Comparative Oncogenomics Implicates the Neurofibromin 1 Gene (NF1) as a Breast Cancer Driver.

Published in:

Genetics, 2012, v. 192, n. 2, p. 385, doi. 10.1534/genetics.112.142802

By:

Wallace, Marsha D.;
Pfefferle, Adam D.;
Shen, Lishuang;
McNairn, Adrian J.;
Cerami, Ethan G.;
Fallon, Barbara L.;
Rinaldi, Vera D.;
Southard, Teresa L.;
Perou, Charles M.;
Schimenti, John C.

Publication type:

Article

Malignant conversion to glioblastoma in neurofibromatosis type I-associated pleomorphic xanthoastrocytoma: Unknown predictors of favorable outcome.

Published in:

2018

By:

Singla, Navneet;
Kapoor, Ankur;
Radotra, B;
Chatterjee, Debajyoti

Publication type:

Case Study

Genomic profile of human meningioma cell lines.

Published in:

PLoS ONE, 2017, v. 12, n. 5, p. 1, doi. 10.1371/journal.pone.0178322

By:

Mei, Yu;
Bi, Wenya Linda;
Greenwald, Noah F.;
Agar, Nathalie Y.;
Beroukhim, Rameen;
Dunn, Gavin P.;
Dunn, Ian F.

Publication type:

Article

Hippocampal Neurofibromin and Amyloid Precursor Protein Expression in Dopamine D Receptor Knock-out Mice Following Passive Avoidance Conditioning.

Published in:

Neurochemical Research, 2013, v. 38, n. 3, p. 564, doi. 10.1007/s11064-012-0949-0

By:

D'Amico, Agata;
Castorina, Alessandro;
Leggio, Gian;
Drago, Filippo;
D'Agata, Velia

Publication type:

Article

A case of pancreatic neuroendocrine tumor in a patient with neurofibromatosis-1.

Published in:

World Journal of Surgical Oncology, 2012, v. 10, n. 1, p. 153, doi. 10.1186/1477-7819-10-153

By:

Takeshi Nishi;
Yasunari Kawabata;
Youko Hari;
Hiroshi Imaoka;
Noriyoshi Ishikawa;
Seiji Yano;
Riruke Maruyama;
Yoshitsugu Tajima

Publication type:

Article

Rab GTPase-Activating Proteins in Autophagy: Regulation of Endocytic and Autophagy Pathways by Direct Binding to Human ATG8 Modifiers.

Published in:

Molecular & Cellular Biology, 2012, v. 32, n. 9, p. 1733, doi. 10.1128/MCB.06717-11

By:

Popovic, Doris;
Akutsu, Masato;
Novak, Ivana;
Harper, J. Wade;
Behrends, Christian;
Dikic, Ivan

Publication type:

Article

Preclinical evaluation of the combination of mTOR and proteasome inhibitors with radiotherapy in malignant peripheral nerve sheath tumors.

Published in:

Journal of Neuro-Oncology, 2014, v. 118, n. 1, p. 83, doi. 10.1007/s11060-014-1422-5

By:

Yamashita, A.;
Baia, G.;
Ho, J.;
Velarde, E.;
Wong, J.;
Gallia, G.;
Belzberg, A.;
Kimura, E.;
Riggins, G.

Publication type:

Article

MEG3: a novel long noncoding potentially tumour-suppressing RNA in meningiomas.

Published in:

Journal of Neuro-Oncology, 2013, v. 112, n. 1, p. 1, doi. 10.1007/s11060-012-1038-6

By:

Balik, Vladimir;
Srovnal, Josef;
Sulla, Igor;
Kalita, Ondrej;
Foltanova, Tatiana;
Vaverka, Miroslav;
Hrabalek, Lumir;
Hajduch, Marian

Publication type:

Article

Computational Modeling of the Neurofibromin-Stimulated Guanosine Triphosphate Hydrolysis by the KRas Protein.

Published in:

Biophysica, 2023, v. 3, n. 2, p. 373, doi. 10.3390/biophysica3020025

By:

Polyakov, Igor;
Nemukhin, Alexander

Publication type:

Article

Psoriasis vulgaris occurring in a known case of neurofibromatosis type I: A rare association.

Published in:

2016

By:

Chalam, Konakanchi Venkata;
Kumar, Gummalla Ajay;
Yandapalli, Padmasri Somala;
P., Anila Sunandini

Publication type:

Case Study

Familial Lymphoproliferative Malignancies and Tandem Duplication of NF1 Gene.

Published in:

2014

By:

Fernandes, Gustavo;
Souto, Mirela;
Costa, Frederico;
Oliveira, Edite;
Garicochea, Bernardo

Publication type:

Case Study

Arg1809 substitution in neurofibromin: further evidence of a genotype-phenotype correlation in neurofibromatosis type 1.

Published in:

European Journal of Human Genetics, 2015, v. 23, n. 11, p. 1460, doi. 10.1038/ejhg.2015.93

By:

Santoro, Claudia;
Maietta, Anna;
Giugliano, Teresa;
Melis, Daniela;
Perrotta, Silverio;
Nigro, Vincenzo;
Piluso, Giulio

Publication type:

Article

Combined MEK Inhibition and BMP2 Treatment Promotes Osteoblast Differentiation and Bone Healing in Nf1Osx−/− Mice.

Published in:

Journal of Bone & Mineral Research, 2015, v. 30, n. 1, p. 55, doi. 10.1002/jbmr.2316

By:

de la Croix Ndong, Jean;
Stevens, David M;
Vignaux, Guillaume;
Uppuganti, Sasidhar;
Perrien, Daniel S;
Yang, Xiangli;
Nyman, Jeffry S;
Harth, Eva;
Elefteriou, Florent

Publication type:

Article

Neurofibromin Deficiency-Associated Transcriptional Dysregulation Suggests a Novel Therapy for Tibial Pseudoarthrosis in NF1.

Published in:

Journal of Bone & Mineral Research, 2014, v. 29, n. 12, p. 2636, doi. 10.1002/jbmr.2298

By:

Paria, Nandina;
Cho, Tae-Joon;
Choi, In Ho;
Kamiya, Nobuhiro;
Kayembe, Kay;
Mao, Rong;
Margraf, Rebecca L;
Obermosser, Gerlinde;
Oxendine, Ila;
Sant, David W;
Song, Mi Hyun;
Stevenson, David A;
Viskochil, David H;
Wise, Carol A;
Kim, Harry KW;
Rios, Jonathan J

Publication type:

Article

Cotargeting MNK and MEK kinases induces the regression of NF1-mutant cancers.

Published in:

2016

By:

Lock, Rebecca;
Ingraham, Rachel;
Maertens, Ophélia;
Miller, Abigail L.;
Weledji, Nelly;
Legius, Eric;
Konicek, Bruce M.;
Yan, Sau-Chi B.;
Graff, Jeremy R.;
Cichowski, Karen

Publication type:

journal article

Ras-ERK signalling in endochondral ossification: insights from neurofibromin.

Published in:

IBMS BoneKEy, 2014, v. 11, n. 1, p. 488, doi. 10.1038/bonekey.2013.222

By:

Schindeler, Aaron;
Deo, Nikita

Publication type:

Article