Works matching DE "NEGATIVE regulatory factor"

Results: 182

MiR-106b-5p improving the progression of chronic kidney disease by inhibiting the TGF-β/Smad pathway.

Published in:

Hereditas, 2025, v. 162, n. 1, p. 1, doi. 10.1186/s41065-025-00468-7

By:

Ma, Qihao;
Xu, Li;
Zhou, Peng;
Yang, Bo;
Li, Yong;
Sun, Danan

Publication type:

Article

Pathological Mechanisms Involved in HIV-Associated Lymphomagenesis: Novel Targeted Therapeutic Approaches.

Published in:

Cells (2073-4409), 2025, v. 14, n. 10, p. 705, doi. 10.3390/cells14100705

By:

Straista, Mihaela;
Caccuri, Francesca;
Arnaut, Nicoleta;
Caruso, Arnaldo;
Slevin, Mark

Publication type:

Article

Mathematical modelling reveals properties of TcdC required for it to be a negative regulator of toxin production in Clostridium difficile.

Published in:

Journal of Mathematical Biology, 2015, v. 70, n. 4, p. 773, doi. 10.1007/s00285-014-0780-0

By:

Jabbari, Sara;
Cartman, Stephen;
King, John

Publication type:

Article

Interferon regulatory factor 3 is a negative regulator of pathological cardiac hypertrophy.

Published in:

Basic Research in Cardiology, 2013, v. 108, n. 2, p. 1, doi. 10.1007/s00395-012-0326-9

By:

Lu, Jing;
Bian, Zhou-Yan;
Zhang, Ran;
Zhang, Yan;
Liu, Chen;
Yan, Ling;
Zhang, Shu-Min;
Jiang, Ding-Sheng;
Wei, Xiang;
Zhu, Xue;
Chen, Manyin;
Wang, Ai-Bing;
Chen, Yingjie;
Yang, Qinglin;
Liu, Peter;
Li, Hongliang

Publication type:

Article

Synergy and allostery in ligand binding by HIV-1 Nef.

Published in:

Biochemical Journal, 2021, v. 478, n. 8, p. 1525, doi. 10.1042/BCJ20201002

By:

Aldehaiman, Abdullah;
Momin, Afaque A.;
Restouin, Audrey;
Luyao Wang;
Xiaoli Shi;
Aljedani, Safia;
Opi, Sandrine;
Lugari, Adrien;
Hameed, Umar F. Shahul;
Ponchon, Luc;
Morelli, Xavier;
Mingdong Huang;
Dumas, Christian;
Collette, Yves;
Arold, Stefan T.

Publication type:

Article

Identification of High Tolerance to Jujube Witches' Broom in Indian Jujube (Ziziphus mauritiana Lam.) and Mining Differentially Expressed Genes Related to the Tolerance through Transcriptome Analysis.

Published in:

Plants (2223-7747), 2023, v. 12, n. 11, p. 2082, doi. 10.3390/plants12112082

By:

Xu, Yaru;
Wang, Chao;
Kong, Decang;
Cao, Ming;
Zhang, Qiong;
Tahir, Muhammad;
Yang, Ying;
Yang, Shuang;
Bo, Wenhao;
Pang, Xiaoming

Publication type:

Article

YWHAG inhibits influenza a virus replication by suppressing the release of viral M2 protein.

Published in:

Frontiers in Microbiology, 2022, v. 13, p. 01, doi. 10.3389/fmicb.2022.951009

By:

Haiying Mao;
Lei Cao;
Ting Xu;
Xiaohan Xia;
Peilei Ren;
Pengfei Han;
Chengfei Li;
Xianfeng Hui;
Xian Lin;
Kun Huang;
Meilin Jin

Publication type:

Article

Melanin Promotes Spore Production in the Rice Blast Fungus Magnaporthe oryzae.

Published in:

Frontiers in Microbiology, 2022, v. 13, p. 1, doi. 10.3389/fmicb.2022.843838

By:

Huang, Pengyun;
Cao, Huijuan;
Li, Yan;
Zhu, Siyi;
Wang, Jing;
Wang, Qing;
Liu, Xiaohong;
Lin, Fu-Cheng;
Lu, Jianping

Publication type:

Article

Lovastatin Inhibits HIV-1-Induced MHC-I Downregulation by Targeting Nef–AP-1 Complex Formation: A New Strategy to Boost Immune Eradication of HIV-1 Infected Cells.

Published in:

Frontiers in Immunology, 2019, p. 1, doi. 10.3389/fimmu.2019.02151

By:

Liu, Bingfeng;
Zhang, Xu;
Zhang, Wanying;
Wu, Liyang;
Jing, Shuliang;
Liu, Weiwei;
Xia, Baijin;
Zou, Fan;
Lu, Lijuan;
Ma, Xiancai;
He, Dalian;
Hu, Qifei;
Zhang, Yiwen;
Deng, Kai;
Cai, Weiping;
Tang, Xiaoping;
Peng, Tao;
Zhang, Hui;
Li, Linghua

Publication type:

Article

A positive role of DBC1 in PEA3-mediated progression of estrogen receptor-negative breast cancer.

Published in:

Oncogene, 2015, v. 34, n. 34, p. 4500, doi. 10.1038/onc.2014.381

By:

Kim, H J;
Kim, S-H;
Yu, E J;
Seo, W-Y;
Kim, J H

Publication type:

Article

The HD-ZIP IV transcription factor Tril regulates fruit spine density through gene dosage effects in cucumber.

Published in:

Journal of Experimental Botany, 2020, v. 71, n. 20, p. 6297, doi. 10.1093/jxb/eraa344

By:

Du, Hui;
Wang, Gang;
Pan, Jian;
Chen, Yue;
Xiao, Tingting;
Zhang, Leyu;
Zhang, Keyan;
Wen, Haifan;
Xiong, Liangrong;
Yu, Yao;
He, Huanle;
Pan, Junsong;
Cai, Run

Publication type:

Article

Weighted lambda superstrings applied to vaccine design.

Published in:

PLoS ONE, 2019, v. 14, n. 2, p. 1, doi. 10.1371/journal.pone.0211714

By:

Martínez, Luis;
Milanič, Martin;
Malaina, Iker;
Álvarez, Carmen;
Pérez, Martín-Blas;
M. de la Fuente, Ildefonso

Publication type:

Article

Large and moderate deviations in testing Rayleigh diffusion model.

Published in:

Statistical Papers, 2013, v. 54, n. 3, p. 591, doi. 10.1007/s00362-012-0450-5

By:

Kuang, Nenghui;
Xie, Huantian

Publication type:

Article

Research Progress of HIV-1 Nef Inhibitors.

Published in:

AIDS Reviews, 2020, v. 22, n. 4, p. 221, doi. 10.24875/AIDSRev.20000050

By:

Yanhan Lv;
Yuanxi Meng;
Jiaqian Zhong;
Junhui Wan;
Wei Zou

Publication type:

Article

HIV-1 Nef CAWLEAQ motif: a regulator of monocytes invasion through ENO1 modulation.

Published in:

Molecular & Cellular Biochemistry, 2018, v. 447, n. 1/2, p. 151, doi. 10.1007/s11010-018-3300-5

By:

Saxena, Reshu;
Vekariya, Umesh Kumar;
Kumar, Pradeep;
Tripathi, Amit Kumar;
Ghosh, Jimut Kanti;
Tripathi, Raj Kamal

Publication type:

Article

Protein tyrosine phosphatase kappa (PTPRK) is a negative regulator of adhesion and invasion of breast cancer cells, and associates with poor prognosis of breast cancer.

Published in:

Journal of Cancer Research & Clinical Oncology, 2013, v. 139, n. 7, p. 1129, doi. 10.1007/s00432-013-1421-5

By:

Sun, Ping-Hui;
Ye, Lin;
Mason, Malcolm;
Jiang, Wen

Publication type:

Article

脊髓损伤后细胞焦亡调控机制及治疗策略.

Published in:

Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu, 2024, v. 28, n. 11, p. 1772, doi. 10.12307/2023.964

By:

尚文雅;
任亚锋;
李冰;
韦慧麟;
张芝兰;
黄晓萌;
黄靖

Publication type:

Article

果实成熟及品质形成的负调控因子研究进展.

Published in:

Journal of Chinese Institute of Food Science & Technology / Zhongguo Shipin Xuebao, 2022, v. 22, n. 9, p. 312, doi. 10.16429/j.1009-7848.2022.09.033

By:

薛茂;
朱本忠;
吴培文;
杜莹琳;
初易洋;
张瑞家

Publication type:

Article

HIV Nef and Antiretroviral Therapy Have an Inhibitory Effect on Autophagy in Human Astrocytes that May Contribute to HIV-Associated Neurocognitive Disorders.

Published in:

Cells (2073-4409), 2020, v. 9, n. 6, p. 1426, doi. 10.3390/cells9061426

By:

Cheney, Laura;
Guzik, Hillary;
Macaluso, Frank P.;
Macian, Fernando;
Cuervo, Ana Maria;
Berman, Joan W.

Publication type:

Article

SIV Infection and the HIV Proteins Tat and Nef Induce Senescence in Adipose Tissue and Human Adipose Stem Cells, Resulting in Adipocyte Dysfunction.

Published in:

Cells (2073-4409), 2020, v. 9, n. 4, p. 854, doi. 10.3390/cells9040854

By:

Gorwood, Jennifer;
Ejlalmanesh, Tina;
Bourgeois, Christine;
Mantecon, Matthieu;
Rose, Cindy;
Atlan, Michael;
Desjardins, Delphine;
Le Grand, Roger;
Fève, Bruno;
Lambotte, Olivier;
Capeau, Jacqueline;
Béréziat, Véronique;
Lagathu, Claire

Publication type:

Article

Plasma Membrane-Associated Restriction Factors and Their Counteraction by HIV-1 Accessory Proteins.

Published in:

Cells (2073-4409), 2019, v. 8, n. 9, p. 1020, doi. 10.3390/cells8091020

By:

Ramirez, Peter W.;
Sharma, Shilpi;
Singh, Rajendra;
Stoneham, Charlotte A.;
Vollbrecht, Thomas;
Guatelli, John

Publication type:

Article

Interactions between HIV proteins and host restriction factors: implications for potential therapeutic intervention in HIV infection.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1390650

By:

Rashid, Farooq;
Zaongo, Silvere D.;
Iqbal, Hifza;
Harypursa, Vijay;
Fangzhou Song;
Yaokai Chen

Publication type:

Article

Brain-specific HIV Nef identified in multiple patients with neurological disease.

Published in:

Journal of NeuroVirology, 2018, v. 24, n. 1, p. 1, doi. 10.1007/s13365-017-0586-0

By:

Lamers, Susanna L.;
Fogel, Gary B.;
Liu, Enoch S.;
Barbier, Andrew E.;
Rodriguez, Christopher W.;
Singer, Elyse J.;
Nolan, David J.;
Rose, Rebecca;
McGrath, Michael S.

Publication type:

Article

HIV-1 transgenic rats display mitochondrial abnormalities consistent with abnormal energy generation and distribution.

Published in:

Journal of NeuroVirology, 2016, v. 22, n. 5, p. 564, doi. 10.1007/s13365-016-0424-9

By:

Villeneuve, Lance;
Purnell, Phillip;
Stauch, Kelly;
Callen, Shannon;
Buch, Shilpa;
Fox, Howard

Publication type:

Article

Nef exosomes isolated from the plasma of individuals with HIV-associated dementia (HAD) can induce Aβ secretion in SH-SY5Y neural cells.

Published in:

Journal of NeuroVirology, 2016, v. 22, n. 2, p. 179, doi. 10.1007/s13365-015-0383-6

By:

Khan, Mahfuz;
Lang, Michelle;
Huang, Ming-Bo;
Raymond, Andrea;
Bond, Vincent;
Shiramizu, Bruce;
Powell, Michael

Publication type:

Article

Microglia-derived HIV Nef+ exosome impairment of the blood-brain barrier is treatable by nanomedicine-based delivery of Nef peptides.

Published in:

Journal of NeuroVirology, 2016, v. 22, n. 2, p. 129, doi. 10.1007/s13365-015-0397-0

By:

Raymond, A.;
Diaz, P.;
Chevelon, S.;
Agudelo, M.;
Yndart-Arias, A.;
Ding, H.;
Kaushik, A.;
Jayant, R.;
Nikkhah-Moshaie, R.;
Roy, U.;
Pilakka-Kanthikeel, S.;
Nair, M.

Publication type:

Article

A novel onco-miR-365 induces cutaneous squamous cell carcinoma.

Published in:

Carcinogenesis, 2013, v. 34, n. 7, p. 1653, doi. 10.1093/carcin/bgt097

By:

Zhou, Meijuan;
Liu, Weilin;
Ma, Shudong;
Cao, Hong;
Peng, Xuebiao;
Guo, Ling;
Zhou, Xinhua;
Zheng, Li;
Guo, Linlang;
Wan, Miaojian;
Shi, Weimin;
He, Yingjie;
Lu, Chao;
Jiang, Lihong;
Ou, Chengshan;
Guo, Yuanxia;
Ding, Zhenhua

Publication type:

Article

ECRG4 is a negative regulator of caspase-8-mediated apoptosis in human T-leukemia cells.

Published in:

Carcinogenesis, 2012, v. 33, n. 5, p. 996, doi. 10.1093/carcin/bgs118

By:

Matsuzaki, Junichi;
Torigoe, Toshihiko;
Hirohashi, Yoshihiko;
Kamiguchi, Kenjiro;
Tamura, Yasuaki;
Tsukahara, Tomohide;
Kubo, Terufumi;
Takahashi, Akari;
Nakazawa, Emiri;
Saka, Eri;
Yasuda, Kazuyo;
Takahashi, Shuji;
Sato, Noriyuki

Publication type:

Article

NF-κB signaling relieves negative regulation by miR-194 in hepatocellular carcinoma by suppressing the transcription factor HNF-1α.

Published in:

Science Signaling, 2015, v. 8, n. 387, p. 1, doi. 10.1126/scisignal.aaa8441

By:

Chunyang Bao;
Yan Li;
Lin Huan;
Yuannv Zhang;
Fangyu Zhao;
Qifeng Wang;
Linhui Liang;
Jie Ding;
Li Liu;
Taoyang Chen;
Jinjun Li;
Ming Yao;
Shenglin Huang;
Xianghuo He

Publication type:

Article

Male X-linked genes in Drosophila melanogaster are compensated independently of the Male-Specific Lethal complex.

Published in:

Epigenetics & Chromatin, 2013, v. 6, n. 1, p. 2, doi. 10.1186/1756-8935-6-35

By:

Philip, Philge;
Stenberg, Per

Publication type:

Article

Comparison of HIV-1 nef and gag Variations and Host HLA Characteristics as Determinants of Disease Progression among HIV-1 Vertically Infected Kenyan Children.

Published in:

PLoS ONE, 2015, v. 10, n. 8, p. 1, doi. 10.1371/journal.pone.0137140

By:

Saina, Matilda Chelimo;
Bi, Xiuqiong;
Lihana, Raphael;
Lwembe, Raphael;
Ishizaki, Azumi;
Panikulam, Annie;
Palakudy, Tresa;
Musoke, Rachel;
Owens, Mary;
Songok, Elijah Maritim;
Ichimura, Hiroshi

Publication type:

Article

HIV-1 Myristoylated Nef Treatment of Murine Microglial Cells Activates Inducible Nitric Oxide Synthase, NO2 Production and Neurotoxic Activity.

Published in:

PLoS ONE, 2015, v. 10, n. 6, p. 1, doi. 10.1371/journal.pone.0130189

By:

Mangino, Giorgio;
Famiglietti, Marylinda;
Capone, Caterina;
Veroni, Caterina;
Percario, Zulema Antonia;
Leone, Stefano;
Fiorucci, Gianna;
Lülf, Sebastian;
Romeo, Giovanna;
Agresti, Cristina;
Persichini, Tiziana;
Geyer, Matthias;
Affabris, Elisabetta

Publication type:

Article

Correction: TRAIL-R1 Is a Negative Regulator of Pro-Inflammatory Responses and Modulates Long-Term Sequelae Resulting from Chlamydia trachomatis Infections in Humans.

Published in:: PLoS ONE, 2014, v. 9, n. 8, p. 1, doi. 10.1371/journal.pone.0106964
Publication type:: Article

A Functional Variant of PTPN22 Confers Risk for Vogt-Koyanagi-Harada Syndrome but Not for Ankylosing Spondylitis.

Published in:

PLoS ONE, 2014, v. 9, n. 5, p. 1, doi. 10.1371/journal.pone.0096943

By:

Zhang, Qi;
Qi, Jian;
Hou, Shengping;
Du, Liping;
Yu, Hongsong;
Cao, Qingfeng;
Zhou, Yan;
Liao, Dan;
Kijlstra, Aize;
Yang, Peizeng

Publication type:

Article

Gibberellin Application at Pre-Bloom in Grapevines Down-Regulates the Expressions of VvIAA9 and VvARF7, Negative Regulators of Fruit Set Initiation, during Parthenocarpic Fruit Development.

Published in:

PLoS ONE, 2014, v. 9, n. 4, p. 1, doi. 10.1371/journal.pone.0095634

By:

Jung, Chan Jin;
Hur, Youn Young;
Yu, Hee-Ju;
Noh, Jung-Ho;
Park, Kyo-Sun;
Lee, Hee Jae

Publication type:

Article

Study of the HIV-2 Env Cytoplasmic Tail Variability and Its Impact on Tat, Rev and Nef.

Published in:

PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0079129

By:

Bakouche, Nordine;
Vandenbroucke, Anne-Thérèse;
Goubau, Patrick;
Ruelle, Jean

Publication type:

Article

A Role for Cytosolic Isocitrate Dehydrogenase as a Negative Regulator of Glucose Signaling for Insulin Secretion in Pancreatic ß-Cells.

Published in:

PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0077097

By:

Guay, Claudiane;
Joly, Érik;
Pepin, Émilie;
Barbeau, Annie;
Hentsch, Lisa;
Pineda, Marco;
Madiraju, S. R. Murthy;
Brunengraber, Henri;
Prentki, Marc

Publication type:

Article

BCL-3 Attenuation of TNFA Expression Involves an Incoherent Feed-Forward Loop Regulated by Chromatin Structure.

Published in:

PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0077015

By:

Walker, Thomas;
Adamson, Antony;
Jackson, Dean A.

Publication type:

Article

Structural Basis for the Interaction of the Adaptor Protein Grb14 with Activated Ras.

Published in:

PLoS ONE, 2013, v. 8, n. 8, p. 1, doi. 10.1371/journal.pone.0072473

By:

Qamra, Rohini;
Hubbard, Stevan R.

Publication type:

Article

nfxB as a Novel Target for Analysis of Mutation Spectra in Pseudomonas aeruginosa.

Published in:

PLoS ONE, 2013, v. 8, n. 6, p. 1, doi. 10.1371/journal.pone.0066236

By:

Monti, Mariela R.;
Morero, Natalia R.;
Miguel, Virginia;
Argaraña, Carlos E.

Publication type:

Article

The Tyrosine Phosphatase PTPN14 Is a Negative Regulator of YAP Activity.

Published in:

PLoS ONE, 2013, v. 8, n. 4, p. 1, doi. 10.1371/journal.pone.0061916

By:

Michaloglou, Chrysiis;
Lehmann, Waltraut;
Martin, Typhaine;
Delaunay, Clara;
Hueber, Andreas;
Barys, Louise;
Niu, Honglin;
Billy, Eric;
Wartmann, Markus;
Ito, Moriko;
Wilson, Christopher J.;
Digan, Mary Ellen;
Bauer, Andreas;
Voshol, Hans;
Christofori, Gerhard;
Sellers, William R.;
Hofmann, Francesco;
Schmelzle, Tobias

Publication type:

Article

Protective Effects of Fluoxetine on Decompression Sickness in Mice.

Published in:

PLoS ONE, 2012, v. 7, n. 11, p. 1, doi. 10.1371/journal.pone.0049069

By:

Blatteau, Jean-Eric;
Barre, Sandrine;
Pascual, Aurelie;
Castagna, Olivier;
Abraini, Jacques H.;
Risso, Jean-Jacques;
Vallee, Nicolas

Publication type:

Article

The Scaffolding Protein Dlg1 Is a Negative Regulator of Cell-Free Virus Infectivity but Not of Cell-to-Cell HIV-1 Transmission in T Cells.

Published in:

PLoS ONE, 2012, v. 7, n. 1, p. 1, doi. 10.1371/journal.pone.0030130

By:

Nzounza, Patrycja;
Chazal, Maxime;
Guedj, Chloé;
Schmitt, Alain;
Massé, Jean-Marc;
Randriamampita, Clotilde;
Pique, Claudine;
Ramirez, Bertha Cecilia

Publication type:

Article

LGR5 Is a Negative Regulator of Tumourigenicity, Antagonizes Wnt Signalling and Regulates Cell Adhesion in Colorectal Cancer Cell Lines.

Published in:

PLoS ONE, 2011, v. 6, n. 7, p. 1, doi. 10.1371/journal.pone.0022733

By:

Walker, Francesca;
Hui-Hua Zhang;
Odorizzi, Annalisa;
Burgess, Antony W.

Publication type:

Article

LyGDI, a Novel SHIP-Interacting Protein, Is a Negative Regulator of Fc&ggr;R-Mediated Phagocytosis.

Published in:

PLoS ONE, 2011, v. 6, n. 6, p. 1, doi. 10.1371/journal.pone.0021175

By:

Mehta, Payal;
Wavreille, Anne-Sophie;
Justiniano, Steven E.;
Marsh, Rachel L.;
Yu, Jianhua;
Burry, Richard W.;
Jarjoura, David;
Eubank, Timothy;
Caligiuri, Michael A.;
Butchar, Jonathan P.;
Tridandapani, Susheela

Publication type:

Article

Searching for Dual Inhibitors of the MDM2-p53 and MDMX-p53 Protein-Protein Interaction by a Scaffold-Hopping Approach.

Published in:

Chemical Biology & Drug Design, 2015, v. 86, n. 2, p. 180, doi. 10.1111/cbdd.12474

By:

Zaytsev, Andrey;
Dodd, Barry;
Magnani, Matteo;
Ghiron, Chiara;
Golding, Bernard T.;
Griffin, Roger J.;
Liu, Junfeng;
Lu, Xiaohong;
Micco, Iolanda;
Newell, David R.;
Padova, Alessandro;
Robertson, Graeme;
Lunec, John;
Hardcastle, Ian R.

Publication type:

Article

Mental health status of Chinese residents during the COVID-19 epidemic.

Published in:

BMC Psychiatry, 2020, v. 20, n. 1, p. N.PAG, doi. 10.1186/s12888-020-02966-6

By:

Jiang, Wen;
Liu, Xuerong;
Zhang, Jingxuan;
Feng, Zhengzhi

Publication type:

Article

Inhibition of polo-like kinase 1 (PLK1) facilitates reactivation of gamma-herpesviruses and their elimination.

Published in:

PLoS Pathogens, 2021, v. 17, n. 7, p. 1, doi. 10.1371/journal.ppat.1009764

By:

Biswas, Ayan;
Zhou, Dawei;
Fiches, Guillaume N.;
Wu, Zhenyu;
Liu, Xuefeng;
Ma, Qin;
Zhao, Weiqiang;
Zhu, Jian;
Santoso, Netty G.

Publication type:

Article

Variation in HIV-1 Nef function within and among viral subtypes reveals genetically separable antagonism of SERINC3 and SERINC5.

Published in:

PLoS Pathogens, 2020, v. 16, n. 9, p. 1, doi. 10.1371/journal.ppat.1008813

By:

Jin, Steven W.;
Mwimanzi, Francis M.;
Mann, Jaclyn K.;
Bwana, Mwebesa Bosco;
Lee, Guinevere Q.;
Brumme, Chanson J.;
Hunt, Peter W.;
Martin, Jeff N.;
Bangsberg, David R.;
Ndung'u, Thumbi;
Brumme, Zabrina L.;
Brockman, Mark A.

Publication type:

Article

Peroxisomes in host defense.

Published in:

PLoS Pathogens, 2020, v. 16, n. 7, p. 1, doi. 10.1371/journal.ppat.1008636

By:

Di Cara, Francesca

Publication type:

Article