Works matching DE "MYELOID leukemia genetics"

Results: 152

N6-Methyladenosine (m6A): A Promising New Molecular Target in Acute Myeloid Leukemia.

Published in:

Frontiers in Oncology, 2019, p. N.PAG, doi. 10.3389/fonc.2019.00251

By:

Ianniello, Zaira;
Paiardini, Alessandro;
Fatica, Alessandro

Publication type:

Article

Noncoding RNAs and their functional involvement in regulation of chronic myeloid leukemia.

Published in:

Briefings in Functional Genomics, 2016, v. 15, n. 3, p. 239, doi. 10.1093/bfgp/elv059

By:

Xuefei Wang;
Ke Chen;
Guijie Guo;
Ji-Long Chen

Publication type:

Article

Arsenic trioxide and bortezomib interact synergistically to induce apoptosis in chronic myelogenous leukemia cells resistant to imatinib mesylate through Bcr/Abl-dependent mechanisms.

Published in:

Molecular Medicine Reports, 2014, v. 10, n. 3, p. 1519, doi. 10.3892/mmr.2014.2333

By:

WENBIN XU;
WEI WEI;
QING YU;
CHAO WU;
CHENJING YE;
YINGLI WU;
HUA YAN

Publication type:

Article

5'UTR point substitutions and N-terminal truncating mutations of ANKRD26 in acute myeloid leukemia.

Published in:

Journal of Hematology & Oncology, 2017, v. 10, p. 1, doi. 10.1186/s13045-016-0382-y

By:

Marconi, Caterina;
Canobbio, Ilaria;
Bozzi, Valeria;
Pippucci, Tommaso;
Simonetti, Giorgia;
Melazzini, Federica;
Angori, Silvia;
Martinelli, Giovanni;
Saglio, Giuseppe;
Torti, Mauro;
Pastan, Ira;
Seri, Marco;
Pecci, Alessandro

Publication type:

Article

Long non-coding RNAs in the regulation of myeloid cells.

Published in:

Journal of Hematology & Oncology, 2016, v. 9, p. 1, doi. 10.1186/s13045-016-0333-7

By:

Xinyu Tian;
Jie Tian;
Xinyi Tang;
Jie Ma;
Shengjun Wang

Publication type:

Article

A mechanism of nucleocytoplasmic trafficking for the homeodomain protein PRH.

Published in:

Molecular & Cellular Biochemistry, 2009, v. 332, n. 1/2, p. 173, doi. 10.1007/s11010-009-0188-0

By:

Jonathan Ploski;
Kevin Park;
Katherine Borden;
Aurelian Radu

Publication type:

Article

FLT3 Inhibition as Therapy in Acute Myeloid Leukemia: A Record of Trials and Tribulations.

Published in:

Oncologist, 2011, v. 16, n. 8, p. 1162, doi. 10.1634/theoncologist.2011-0084

By:

FATHI, AMIR T.;
CHABNER, BRUCE A.

Publication type:

Article

MiR‐486 promotes proliferation and suppresses apoptosis in myeloid cells by targeting Cebpa in vitro.

Published in:

Cancer Medicine, 2018, v. 7, n. 9, p. 4627, doi. 10.1002/cam4.1694

By:

Jiang, Jingwei;
Gao, Qingmin;
Gong, Yiwei;
Huang, Lizhen;
Lin, Hao;
Zhou, Xinli;
Liang, Xiaohua;
Guo, Weijian

Publication type:

Article

Long noncoding RNA LINC00152 promotes cell proliferation through competitively binding endogenous miR‐125b with MCL‐1 by regulating mitochondrial apoptosis pathways in ovarian cancer.

Published in:

Cancer Medicine, 2018, v. 7, n. 9, p. 4530, doi. 10.1002/cam4.1547

By:

Chen, Puxiang;
Fang, Xiaolin;
Xia, Bing;
Zhao, Yan;
Li, Qiaoyan;
Wu, Xiaoying

Publication type:

Article

Loss of PALB2 predicts poor prognosis in acute myeloid leukemia and suggests novel therapeutic strategies targeting the DNA repair pathway.

Published in:

Blood Cancer Journal, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41408-020-00396-x

By:

Padella, Antonella;
Fontana, Maria Chiara;
Marconi, Giovanni;
Fonzi, Eugenio;
Petracci, Elisabetta;
Ferrari, Anna;
Baldazzi, Carmen;
Papayannidis, Cristina;
Ghelli Luserna Di Rorá, Andrea;
Testoni, Nicoletta;
Castellani, Gastone;
Haferlach, Torsten;
Martinelli, Giovanni;
Simonetti, Giorgia

Publication type:

Article

The RUNX1-ETO target gene RASSF2 suppresses t(8;21) AML development and regulates Rac GTPase signaling.

Published in:

Blood Cancer Journal, 2020, v. 10, n. 2, p. 1, doi. 10.1038/s41408-020-0282-9

By:

Stoner, Samuel A.;
Liu, Katherine Tin Heng;
Andrews, Elizabeth T.;
Liu, Mengdan;
Arimoto, Kei-Ichiro;
Yan, Ming;
Davis, Amanda G.;
Weng, Stephanie;
Dow, Michelle;
Xian, Su;
DeKelver, Russell C.;
Carter, Hannah;
Zhang, Dong-Er

Publication type:

Article

A novel machine-learning-derived genetic score correlates with measurable residual disease and is highly predictive of outcome in acute myeloid leukemia with mutated NPM1.

Published in:

2019

By:

Patkar, Nikhil;
Shaikh, Anam Fatima;
Kakirde, Chinmayee;
Nathany, Shrinidhi;
Ramesh, Hridya;
Bhanshe, Prasanna;
Joshi, Swapnali;
Chaudhary, Shruti;
Kannan, Sadhana;
Khizer, Syed Hasan;
Chatterjee, Gaurav;
Tembhare, Prashant;
Shetty, Dhanalaxmi;
Gokarn, Anant;
Punatkar, Sachin;
Bonda, Avinash;
Nayak, Lingaraj;
Jain, Hasmukh;
Khattry, Navin;
Bagal, Bhausaheb

Publication type:

Letter

Clinical remission following ascorbate treatment in a case of acute myeloid leukemia with mutations in TET2 and WT1.

Published in:

Blood Cancer Journal, 2019, v. 9, n. 10, p. N.PAG, doi. 10.1038/s41408-019-0242-4

By:

Das, Andrew B.;
Kakadia, Purvi M.;
Wojcik, Damian;
Pemberton, Lucy;
Browett, Peter J.;
Bohlander, Stefan K.;
Vissers, Margreet C. M.

Publication type:

Article

Imatinib-sensitive myeloid neoplasm with low allele burden of FIP1L1- PDGFRA fusion gene in an elderly patient.

Published in:

Geriatrics & Gerontology International, 2016, v. 16, n. 12, p. 1346, doi. 10.1111/ggi.12733

By:

Mohammad, Sherwet;
Gotoh, Akihiko;
Morishita, Soji;
Komatsu, Norio

Publication type:

Article

Identification of ubiquitination-related hub genes in chronic myeloid leukemia cell by bioinformatics analysis.

Published in:

Journal of Cancer, 2024, v. 15, n. 12, p. 3750, doi. 10.7150/jca.96405

By:

Qian Zhou;
Zhuoran Li;
Li Meng;
Ying Wang;
Ashaq, Muhammad Sameer;
Yuan Li;
Baobing Zhao

Publication type:

Article

Bmi-1 over-expression plays a secondary role in chronic myeloid leukemia transformation.

Published in:

Leukemia & Lymphoma, 2007, v. 48, n. 4, p. 793, doi. 10.1080/10428190601186002

By:

Merkerova, Michaela;
Bruchova, Hana;
Kracmarova, Alzbeta;
Klamova, Hana;
Brdicka, Radim

Publication type:

Article

Telomere Dynamics and Genetic Instability in Disease Progression of Chronic Myeloid Leukemia.

Published in:

Leukemia & Lymphoma, 2000, v. 40, n. 1/2, p. 49, doi. 10.3109/10428190009054880

By:

Ohyashiki, Kazuma;
Iwama, Hiroshi;
Tauchi, Tetsuzo;
Shimamoto, Takashi;
Hayashi, Shigefumi;
Ando, Keiko;
Kawakubo, Ken;
Ohyashiki, Junko H.

Publication type:

Article

TET2 Inhibits Differentiation of Embryonic Stem Cells but Does Not Overcome Methylation-Induced Gene Silencing.

Published in:

Bone Marrow Research, 2014, p. 1, doi. 10.1155/2014/986571

By:

Norman, Louis;
Tarrant, Paul;
Chevassut, Timothy

Publication type:

Article

Renin-Angiotensin System (RAS) Expressions in Myeloid Leukemic Cell Lines.

Published in:

UHOD: International Journal of Hematology & Oncology / Uluslararasi Hematoloji Onkoloji Dergisi, 2013, v. 23, n. 4, p. 264, doi. 10.4999/uhod.13014

By:

UZ, Burak;
TATONYAN, Suzin C.;
SAYITOGLU, Muge;
ERBILGIN, Yucel;
HATIRNAZ NG, Ozden;
BUYUKASIK, Yahya;
AKSU, Salih;
SAYINALP, Nilgun;
GOKER, Hakan;
OZCEBE, Osman I.;
OZBEK, Ugur;
HAZNEDAROGLU, Ibrahim C.

Publication type:

Article

Low Ten-eleven-translocation 2 (TET2) transcript level is independent of TET2 mutation in patients with myeloid neoplasms.

Published in:

Diagnostic Pathology, 2016, v. 11, p. 1, doi. 10.1186/s13000-016-0476-4

By:

Scopim-Ribeiro, Renata;
Machado-Neto, João Agostinho;
de Melo Campos, Paula;
Soares Niemann, Fernanda;
Lorand-Metze, Irene;
Ferreira Costa, Fernando;
Olalla Saad, Sara Teresinha;
Traina, Fabiola

Publication type:

Article

Functional Niche Competition Between Normal Hematopoietic Stem and Progenitor Cells and Myeloid Leukemia Cells.

Published in:

Stem Cells, 2015, v. 33, n. 12, p. 3635, doi. 10.1002/stem.2208

By:

Glait-Santar, Chen;
Feng, Xingmin;
Bat, Taha;
Chen, Jichun;
Larochelle, Andre;
Dunbar, Cynthia E.;
Desmond, Ronan;
Heuston, Elisabeth;
Bodine, David M.;
Mizukawa, Benjamin;
Mulloy, James C.

Publication type:

Article

Dominant-negative mutations of CEBPA, encoding CCAAT/enhancer binding protein-α (C/EBPα), in acute myeloid leukemia.

Published in:

Nature Genetics, 2001, v. 27, n. 3, p. 263, doi. 10.1038/85820

By:

Pabst, Thomas;
Mueller, Beatrice U.;
Zhang, Pu;
Radomska, Hanna S.;
Narravula, Sailaja;
Schnittger, Susanne;
Behre, Gerhard;
Hiddemann, Wolfgang;
Tenen, Daniel G.

Publication type:

Article

Lineage development of hematopoietic stem and progenitor cells.

Published in:

Biological Chemistry, 2008, v. 389, n. 7, p. 813, doi. 10.1515/BC.2008.092

By:

Giebel, Bernd;
Punzel, Michael

Publication type:

Article

Gene expression profile and long non-coding RNA analysis, using RNA-Seq, in chicken embryonic fibroblast cells infected by avian leukosis virus J.

Published in:

Archives of Virology, 2018, v. 163, n. 3, p. 639, doi. 10.1007/s00705-017-3659-8

By:

Hu, Xuming;
Chen, Shihao;
Jia, Chongxin;
Xue, Songlei;
Dou, Chunfeng;
Dai, Zhenqing;
Xu, Hui;
Sun, Zhen;
Geng, Tuoyu;
Cui, Hengmi

Publication type:

Article

DNMT3A co-mutation is required for FLT3-ITD as an adverse prognostic indicator in intermediate-risk cytogenetic group AML.

Published in:

Leukemia & Lymphoma, 2018, v. 59, n. 8, p. 1938, doi. 10.1080/10428194.2017.1397659

By:

Ma, Juan;
Shen, Lisong;
Dunlap, Jennifer;
Press, Richard;
Fan, Guang;
Paliga, Aleksandra;
Traer, Elie

Publication type:

Article

Salvianolic acid A, a novel PI3K/Akt inhibitor, induces cell apoptosis and suppresses tumor growth in acute myeloid leukemia.

Published in:

Leukemia & Lymphoma, 2018, v. 59, n. 8, p. 1959, doi. 10.1080/10428194.2017.1399314

By:

Zhou, Jeff Xiwu;
Jiang, Lei;
Pei, Renzhi;
Si, Ting;
Lu, Ying

Publication type:

Article

Detection of clonal heterogeneity and targetable mutations in myeloid sarcoma by high-throughput sequencing.

Published in:

Leukemia & Lymphoma, 2017, v. 58, n. 4, p. 1008, doi. 10.1080/10428194.2016.1225208

By:

Pastoret, Cedric;
Houot, Roch;
Llamas-Gutierrez, Francisco;
Boulland, Marie-Laure;
Marchand, Tony;
Tas, Patrick;
Ly-Sunnaram, Beatrice;
Gandemer, Virginie;
Lamy, Thierry;
Roussel, Mikael;
Fest, Thierry

Publication type:

Article

Pharmacologic maintenance strategies following allogeneic hematopoietic cell transplantation for acute myeloid leukemia.

Published in:

Leukemia & Lymphoma, 2017, v. 58, n. 3, p. 516, doi. 10.1080/10428194.2016.1205744

By:

Lee, Catherine J.;
Shiraz, Parveen;
Muffly, Lori

Publication type:

Article

MUC1 in hematological malignancies.

Published in:

Leukemia & Lymphoma, 2016, v. 57, n. 11, p. 2489, doi. 10.1080/10428194.2016.1195500

By:

Stroopinsky, Dina;
Kufe, Donald;
Avigan, David

Publication type:

Article

Absence of BRAF V600E mutation in a cohort of 402 patients with various chronic and acute myeloid neoplasms.

Published in:

Leukemia & Lymphoma, 2012, v. 53, n. 12, p. 2496, doi. 10.3109/10428194.2012.668188

By:

Trifa, Adrian P.;
Popp, Radu A.;
Cucuianu, Andrei;
Coadă, Camelia A.;
Urian, Laura G.;
Militaru, Mariela S.;
Bănescu, Claudia;
Dima, Delia;
Farcaş, Marius F.;
Crişan, Tania O.;
Petrov, Ljubomir;
Gug, Cristina;
Pop, Ioan V.

Publication type:

Article

Trisomy 8 Acute Myeloid Leukemia Analysis Reveals New Insights of DNA Methylome with Identification of HHEX as Potential Diagnostic Marker.

Published in:

Biomarkers in Cancer, 2015, n. 7, p. 1, doi. 10.4137/BIC.S19614

By:

Saied, Marwa H.;
Marzec, Jacek;
Khalid, Sabah;
Smith, Paul;
Molloy, Gael;
Young, Bryan D.

Publication type:

Article

Early BCR-ABL1 Transcript Decline after 1 Month of Tyrosine Kinase Inhibitor Therapy as an Indicator for Treatment Response in Chronic Myeloid Leukemia.

Published in:

PLoS ONE, 2017, v. 12, n. 1, p. 1, doi. 10.1371/journal.pone.0171041

By:

El Missiry, Mohamed;
Hjorth-Hansen, Henrik;
Richter, Johan;
Olson-Strömberg, Ulla;
Stenke, Leif;
Porkka, Kimmo;
Kreutzman, Anna;
Mustjoki, Satu

Publication type:

Article

NUDT2 Disruption Elevates Diadenosine Tetraphosphate (Ap4A) and Down-Regulates Immune Response and Cancer Promotion Genes.

Published in:

PLoS ONE, 2016, v. 11, n. 5, p. 1, doi. 10.1371/journal.pone.0154674

By:

Marriott, Andrew S.;
Vasieva, Olga;
Fang, Yongxiang;
Copeland, Nikki A.;
McLennan, Alexander G.;
Jones, Nigel J.

Publication type:

Article

Genome-Wide CRISPR-Cas9 Screen Identifies MicroRNAs That Regulate Myeloid Leukemia Cell Growth.

Published in:

PLoS ONE, 2016, v. 11, n. 4, p. 1, doi. 10.1371/journal.pone.0153689

By:

Wallace, Jared;
Hu, Ruozhen;
Mosbruger, Timothy L.;
Dahlem, Timothy J.;
Stephens, W. Zac;
Rao, Dinesh S.;
Round, June L.;
O’Connell, Ryan M.

Publication type:

Article

The preferential occurrence of FLT3- TKD mutations in inv(16) AML and impact on survival outcome: a combined analysis of 1053 core-binding factor AML patients.

Published in:

British Journal of Haematology, 2013, v. 160, n. 4, p. 557, doi. 10.1111/bjh.12131

By:

Kok, Chung H.;
Brown, Anna L.;
Perugini, Michelle;
Iarossi, Diana G.;
Lewis, Ian D.;
D'Andrea, Richard J.

Publication type:

Article

Regulation of the adaptor molecule LAT2, an in vivo target gene of AML1/ETO ( RUNX1/RUNX1T1), during myeloid differentiation.

Published in:

British Journal of Haematology, 2011, v. 153, n. 5, p. 612, doi. 10.1111/j.1365-2141.2011.08586.x

By:

Duque-Afonso, Jesús;
Solari, Leticia;
Essig, Aitomi;
Berg, Tobias;
Pahl, Heike L.;
Lübbert, Michael

Publication type:

Article

A new player SETs in myeloid malignancy.

Published in:

Nature Genetics, 2013, v. 45, n. 8, p. 846, doi. 10.1038/ng.2709

By:

Trimarchi, Thomas;
Ntziachristos, Panagiotis;
Aifantis, Iannis

Publication type:

Article

Somatic SETBP1 mutations in myeloid malignancies.

Published in:

Nature Genetics, 2013, v. 45, n. 8, p. 942, doi. 10.1038/ng.2696

By:

Makishima, Hideki;
Yoshida, Kenichi;
Nguyen, Nhu;
Przychodzen, Bartlomiej;
Sanada, Masashi;
Okuno, Yusuke;
Ng, Kwok Peng;
Gudmundsson, Kristbjorn O;
Vishwakarma, Bandana A;
Jerez, Andres;
Gomez-Segui, Ines;
Takahashi, Mariko;
Shiraishi, Yuichi;
Nagata, Yasunobu;
Guinta, Kathryn;
Mori, Hiraku;
Sekeres, Mikkael A;
Chiba, Kenichi;
Tanaka, Hiroko;
Muramatsu, Hideki

Publication type:

Article

The Role of Mitochondrial DNA Damage and Repair in the Resistance of BCR/ABL-Expressing Cells to Tyrosine Kinase Inhibitors.

Published in:

International Journal of Molecular Sciences, 2013, v. 14, n. 8, p. 16348, doi. 10.3390/ijms140816348

By:

Glowacki, Sylwester;
Synowiec, Ewelina;
Blasiak, Janusz

Publication type:

Article

Nuclear Repositioning of the Non-Translocated HLXB9 Allele in the Leukaemia Cell Line GDM-1 Harbouring a t(6;7)(q23;q36).

Published in:

Cytogenetic & Genome Research, 2018, v. 153, n. 1, p. 10, doi. 10.1159/000480745

By:

Federico, Concetta;
Leotta, Claudia G.;
Bruno, Francesca;
Longo, Anna M.;
Owoka, Temitayo;
Tosi, Sabrina;
Saccone, Salvatore

Publication type:

Article

Coexpression of NUP98/TOP1 and TOP1/NUP98 in de novo Acute Myeloid Leukemia with t(11;20)(p15;q12) and t(2;5)(q33;q31).

Published in:

Cytogenetic & Genome Research, 2017, v. 150, n. 3/4, p. 287, doi. 10.1159/000458168

By:

Yamamoto, Katsuya;
Minami, Yosuke;
Yakushijin, Kimikazu;
Mizutani, Yu;
Inui, Yumiko;
Kawamoto, Shinichiro;
Matsui, Keiji;
Nakamachi, Yuji;
Kawano, Seiji;
Matsuoka, Hiroshi;
Minami, Hironobu

Publication type:

Article

Identification of a Cryptic Insertion ins(11;X) (q23;q28q12) Resulting in a KMT2A - FLNA Fusion in a 13-Month-Old Child with Acute Myelomonocytic Leukemia.

Published in:

Cytogenetic & Genome Research, 2017, v. 150, n. 3/4, p. 281, doi. 10.1159/000458165

By:

Lentes, Jana;
Thomay, Kathrin;
Schneider, Dominik T.;
Bernbeck, Benedikt;
Reinhardt, Dirk;
Marschalek, Rolf;
Meyer, Claus;
Schlegelberger, Brigitte;
Göhring, Gudrun

Publication type:

Article

The Dicentric Chromosome dic(20;22) Is a Recurrent Abnormality in Myelodysplastic Syndromes and Is a Product of Telomere Fusion.

Published in:

Cytogenetic & Genome Research, 2017, v. 150, n. 3/4, p. 262, doi. 10.1159/000456677

By:

MacKinnon, Ruth N.;
Duivenvoorden, Hendrika M.;
Campbell, Lynda J.;
Wall, Meaghan

Publication type:

Article

Successful treatment of childhood Philadelphia chromosome-positive acute myeloid leukemia.

Published in:

Pediatrics International, 2011, v. 53, n. 4, p. 598, doi. 10.1111/j.1442-200X.2010.03262.x

By:

Xiaojuan Chen;
Wenyu Yang;
Xiaofan Zhu

Publication type:

Article

The BCR gene recombines preferentially with Alu elements in complex BCR-ABL translocations of chronic myeloid leukaemia.

Published in:

Human Molecular Genetics, 1998, v. 7, n. 5, p. 767, doi. 10.1093/hmg/7.5.767

By:

Jeffs, Aaron R.;
Benjes, Suzanne M.;
Smith, Tania L.;
Sowerby, Stephen J.;
Morris, Christine M.

Publication type:

Article

Integration of Hedgehog and mutant FLT3 signaling in myeloid leukemia.

Published in:

Science Translational Medicine, 2015, v. 7, n. 291, p. 1, doi. 10.1126/scitranslmed.aaa5731

By:

Yiting Lim;
Gondek, Lukasz;
Li Li;
Qiuju Wang;
Haley Ma;
Chang, Emily;
Huso, David L.;
Foerster, Sarah;
Marchionni, Luigi;
McGovern, Karen;
Watkins, David Neil;
Peacock, Craig D.;
Levis, Mark;
Smith, Bruce Douglas;
Merchant, Akil A.;
Small, Donald;
Matsui, William

Publication type:

Article

Myeloid Leukemia Factor.

Published in:

Transcription (2154-1264), 2012, v. 3, n. 5, p. 1

By:

Gobert, Vanessa;
Haenlin, Marc;
Waltzer, Lucas

Publication type:

Article

Leukemia Stem Cell-Released Microvesicles Promote the Survival and Migration of Myeloid Leukemia Cells and These Effects Can Be Inhibited by MicroRNA34a Overexpression.

Published in:

Stem Cells International, 2016, p. 1, doi. 10.1155/2016/9313425

By:

Wang, Yue;
Cheng, Qian;
Liu, Jing;
Dong, Min

Publication type:

Article

The natural anti-tumor compound Celastrol targets a Myb-C/EBPβ-p300 transcriptional module implicated in myeloid gene expression.

Published in:

PLoS ONE, 2018, v. 13, n. 2, p. 1, doi. 10.1371/journal.pone.0190934

By:

Coulibaly, Anna;
Haas, Astrid;
Steinmann, Simone;
Jakobs, Anke;
Schmidt, Thomas J.;
Klempnauer, Karl-Heinz

Publication type:

Article

Gender difference in NASH susceptibility: Roles of hepatocyte Ikkβ and Sult1e1.

Published in:

PLoS ONE, 2017, v. 12, n. 8, p. 1, doi. 10.1371/journal.pone.0181052

By:

Matsushita, Noriko;
Hassanein, Mohamed T.;
Martinez-Clemente, Marcos;
Lazaro, Raul;
French, Samuel W.;
Xie, Wen;
Lai, Keane;
Karin, Michael;
Tsukamoto, Hidekazu

Publication type:

Article