Works matching DE "MUSCARINIC agonists"

Results: 238

Early outpatient clinical experience with xanomeline and trospium chloride for schizophrenia: a case report.

Published in:

Frontiers in Psychiatry, 2025, p. 1, doi. 10.3389/fpsyt.2025.1630574

By:

Price, Maxwell Zachary;
Price, Richard Louis

Publication type:

Article

Efficacy in Using Urodynamic Parameters of Intravesical Electrical Stimulation for Detrusor Underactivity.

Published in:

2025

By:

Kmar, Anil;
Sivastava, Aviral;
Tripathy, Rachana;
Kumar, Lalit;
Singh, Yashasvi;
Kumar, Ujwal;
Trivedi, Sameer;
Sankhwar, S. N.

Publication type:

Letter

Study shows improved schizophrenia negative symptoms with xanomeline‐trospium.

Published in:: Brown University Psychopharmacology Update, 2025, v. 36, n. 6, p. 8, doi. 10.1002/pu.31318
Publication type:: Article

Xanomeline‐trospium significantly improves cognition in acute schizophrenia.

Published in:: Brown University Psychopharmacology Update, 2025, v. 36, n. 4, p. 1, doi. 10.1002/pu.31284
Publication type:: Article

Approval.

Published in:: Brown University Psychopharmacology Update, 2025, v. 36, n. 1, p. 8, doi. 10.1002/pu.31258
Publication type:: Article

Adults using clozapine have lower relapse rate, more adverse events.

Published in:: Brown University Psychopharmacology Update, 2025, v. 36, n. 1, p. 6, doi. 10.1002/pu.31255
Publication type:: Article

Second Phase 3 trial shows benefit of xanomeline‐trospium in schizophrenia.

Published in:: Brown University Psychopharmacology Update, 2024, v. 35, n. 8, p. 4, doi. 10.1002/pu.31190
Publication type:: Article

Xanomeline‐trospium combination shows strong results in schizophrenia trial.

Published in:: Brown University Psychopharmacology Update, 2024, v. 35, n. 4, p. 1, doi. 10.1002/pu.31139
Publication type:: Article

Xanomeline‐trospium combination shows promise in treatment of schizophrenia.

Published in:: Brown University Psychopharmacology Update, 2021, v. 32, n. 6, p. 1, doi. 10.1002/pu.30725
Publication type:: Article

Cholinergic Modulation of Epithelial Integrity in the Proximal Colon of Pigs.

Published in:

Cells Tissues Organs, 2013, v. 197, n. 5, p. 411, doi. 10.1159/000345437

By:

Lesko, Szilvia;
Wessler, Ignaz;
Gäbel, Gotthold;
Petto, Carola;
Pfannkuche, Helga

Publication type:

Article

Structure and diversity of insect nicotinic acetylcholine receptors.

Published in:

Pest Management Science, 2001, v. 57, n. 10, p. 914, doi. 10.1002/ps.349

By:

Tomizawa, Motohiro;
Casida, John E

Publication type:

Article

Neurotransmitter Dysfunction in Irritable Bowel Syndrome: Emerging Approaches for Management.

Published in:

Journal of Clinical Medicine, 2021, v. 10, n. 15, p. 3429, doi. 10.3390/jcm10153429

By:

Gros, Mónica;
Gros, Belén;
Mesonero, José Emilio;
Latorre, Eva

Publication type:

Article

Airway Smooth Muscle Regulated by Oxidative Stress in COPD.

Published in:

Antioxidants, 2023, v. 12, n. 1, p. 142, doi. 10.3390/antiox12010142

By:

Kume, Hiroaki;
Yamada, Ryuki;
Sato, Yuki;
Togawa, Ryuichi

Publication type:

Article

Cancer treatment-related xerostomia: basics, therapeutics, and future perspectives.

Published in:

European Journal of Medical Research, 2024, v. 29, n. 1, p. 1, doi. 10.1186/s40001-024-02167-x

By:

Hosseini, Mohammad-Salar;
Sanaie, Sarvin;
Mahmoodpoor, Ata;
Jabbari Beyrami, Saba;
Jabbari Beyrami, Hossein;
Fattahi, Shirin;
Jahanshahlou, Farid;
Zarei, Mahdi;
Rahimi Mamaghani, Alireza;
Kuchaki Rafsanjani, Mahshid

Publication type:

Article

Using insecticidal compounds to elucidate the potential role of neurotransmitters in Lepidoptera pupal ecdysis.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-88623-y

By:

Krishnan, Niranjana;
Gorman, Cassandra;
Stewart, Jillian;
Bradbury, Steven;
Jurenka, Russell

Publication type:

Article

Population‐Based Characterization of the Pharmacokinetics and Food Effect of ANAVEX3‐71, a Novel Sigma‐1 Receptor and Allosteric M1 Muscarinic Receptor Agonist in Development for Treatment of Frontotemporal Dementia, Schizophrenia, and Alzheimer Disease

Published in:

Clinical Pharmacology in Drug Development, 2024, v. 13, n. 1, p. 21, doi. 10.1002/cpdd.1323

By:

Fadiran, Emmanuel O.;
Hammond, Edward;
Tran, James;
Missling, Christopher U.;
Ette, Ene

Publication type:

Article

Concentration–QTc Relationship from a Single Ascending Dose Study of ANAVEX3‐71, a Novel Sigma‐1 Receptor and Allosteric M1 Muscarinic Receptor Agonist in Development for the Treatment of Frontotemporal Dementia, Schizophrenia, and Alzheimer's Disease

Published in:

Clinical Pharmacology in Drug Development, 2023, v. 12, n. 9, p. 888, doi. 10.1002/cpdd.1303

By:

Fadiran, Emmanuel O.;
Hammond, Edward;
Tran, James;
Xue, Hongqi;
Chen, Janell;
Kaufmann, Walter E.;
Missling, Christopher U.;
Darpo, Borje

Publication type:

Article

Pharmacokinetics and pharmacodynamics of GSK961081, a novel inhaled muscarinic antagonist β<sub>2</sub>-agonist, and fluticasone propionate administered alone, concurrently and as a combination blend formulation in healthy volunteers.

Published in:

Clinical Pharmacology in Drug Development, 2014, v. 3, n. 4, p. 305, doi. 10.1002/cpdd.105

By:

Norris, Virginia;
Ambery, Claire;
Riley, Trevor

Publication type:

Article

The role and mechanism of tight junctions in the regulation of salivary gland secretion.

Published in:

Oral Diseases, 2024, v. 30, n. 1, p. 3, doi. 10.1111/odi.14549

By:

Cong, Xin;
Mao, Xiang‐Di;
Wu, Li‐Ling;
Yu, Guang‐Yan

Publication type:

Article

Comparing the effectiveness and adverse effects of pilocarpine and cevimeline in patients with hyposalivation.

Published in:

Oral Diseases, 2019, v. 25, n. 8, p. 1937, doi. 10.1111/odi.13192

By:

Farag, Arwa M.;
Holliday, Craig;
Cimmino, Joseph;
Roomian, Tamar;
Papas, Athena

Publication type:

Article

Neural KCNQ (Kv7) channels.

Published in:

2009

By:

Brown, David A.;
Passmore, Gayle M.

Publication type:

journal article

beta(1)- and beta(2)-adrenoceptor responses in cardiomyocytes derived from human embryonic stem cells: comparison with failing and non-failing adult human heart.

Published in:

2008

By:

Brito-Martins, M.;
Harding, S. E.;
Ali, N. N.

Publication type:

journal article

Effects of synaptotagmin reveal two distinct mechanisms of agonist-stimulated internalization of the M4 muscarinic acetylcholine receptor.

Published in:

2005

By:

Madziva, Michael T.;
Bai, Jihong;
Bhalla, Akhil;
Chapman, Edwin R.;
Edwardson, J. Michael

Publication type:

journal article

Increased function of inhibitory neuronal M2 muscarinic receptors in trachea and ileum of diabetic rats.

Published in:

2002

By:

Coulson, Fiona R;
Jacoby, David B;
Fryer, Allison D

Publication type:

journal article

Investigation of the effects of oxotremorine and amitriptyline on the development of morphine dependence in mice.

Published in:

Anatomy: International Journal of Experimental & Clinical Anatomy, 2022, v. 16, p. 270, doi. 10.2399/ana.22.003s

By:

Birer, Evrim Zeren;
Nurten, Asiye;
Enginar, Nurhan

Publication type:

Article

Half a century in neuroscience: what I can and can't do with memories.

Published in:

Anatomy: International Journal of Experimental & Clinical Anatomy, 2022, v. 16, p. 195, doi. 10.2399/ana.22.003s

By:

Ulus, İsmail H.

Publication type:

Article

Development of an ex vivo model for pharmacological experimentation on isolated tissue preparation.

Published in:

Journal of Advanced Pharmaceutical Technology & Research, 2012, v. 3, n. 3, p. 176, doi. 10.4103/2231-4040.101013

By:

Jain, Gaurav;
Bodakse, Surendra H.;
Namdev, Kantaprasad;
Rajput, Mithun S.;
Mishra, Saurabh

Publication type:

Article

Muscarinic Receptors as Targets for Metronomic Therapy in Ovarian Cancer.

Published in:

Duzce Medical Journal, 2023, v. 25, n. 3, p. 225, doi. 10.18678/dtfd.1315416

By:

SÖYLEMEZ, Fatma;
TÜRKSEVEN, Çağatay Han

Publication type:

Article

Hippocampal M1 receptor function associated with spatial learning and memory in aged female rhesus macaques.

Published in:

Age (0161-9152), 2011, v. 33, n. 3, p. 309, doi. 10.1007/s11357-010-9184-2

By:

Haley, Gwendolen;
Kroenke, Chris;
Schwartz, Daniel;
Kohama, Steven;
Urbanski, Henryk;
Raber, Jacob

Publication type:

Article

Beta-3 Agonists and Anticholinergic Combination for OAB--New Frontier or More of the Same?

Published in:

AUANews, 2014, v. 19, n. 1, p. 1

By:

Rovner, Eric S.;
MacLachlan, Lara S.

Publication type:

Article

Effects of Carbachol on the Excitatory Muscarinic Cholinergic Receptors in Urinary Bladder and Plasma Inflammatory Mediators in Anesthetized Rats.

Published in:

Indian Journal of Pharmaceutical Sciences, 2020, v. 82, p. 38

By:

DAHAI, Q.;
LEI, C.;
ZHAO HONGYU;
YONGJIAN, Y.

Publication type:

Article

Graded Transmission without Action Potentials Sustains Rhythmic Activity in Some But Not All Modulators That Activate the Same Current.

Published in:

Journal of Neuroscience, 2018, v. 38, n. 42, p. 8976, doi. 10.1523/JNEUROSCI.2632-17.2018

By:

Rosenbaum, Philipp;
Marder, Eve

Publication type:

Article

Muscarinic Attenuation of Mnemonic Rule Representation in Macaque Dorsolateral Prefrontal Cortex during a Pro- and Anti-Saccade Task.

Published in:

Journal of Neuroscience, 2015, v. 35, n. 49, p. 16064, doi. 10.1523/JNEUROSCI.2454-15.2015

By:

Major, Alex J.;
Vijayraghavan, Susheel;
Everling, Stefan

Publication type:

Article

The effects of C5aR1 on leukocyte infiltration following pilocarpine-induced status epilepticus.

Published in:

Epilepsia (Series 4), 2017, v. 58, n. 4, p. e54, doi. 10.1111/epi.13698

By:

Benson, Melissa J.;
Manzanero, Silvia;
Borges, Karin

Publication type:

Article

Mapping a mouse limbic seizure susceptibility locus on chromosome 10.

Published in:

Epilepsia (Series 4), 2011, v. 52, n. 11, p. 2076, doi. 10.1111/j.1528-1167.2011.03256.x

By:

Winawer, Melodie R.;
Gildersleeve, Sandra S.;
Phillips, Austin G.;
Rabinowitz, Daniel;
Palmer, Abraham A.

Publication type:

Article

Effect of cevimeline and different concentration of gum arabic on parotid salivary gland function in methotrexate-induced xerostomia: a comparative study.

Published in:

BMC Oral Health, 2024, v. 24, n. 1, p. 1, doi. 10.1186/s12903-024-04374-8

By:

Aboulfotoh, Mahmoud Mohamed

Publication type:

Article

Three‐Photon Infrared Stimulation of Endogenous Neuroreceptors in Vivo.

Published in:

Angewandte Chemie, 2023, v. 135, n. 51, p. 1, doi. 10.1002/ange.202311181

By:

Sortino, Rosalba;
Cunquero, Marina;
Castro‐Olvera, Gustavo;
Gelabert, Ricard;
Moreno, Miquel;
Riefolo, Fabio;
Matera, Carlo;
Fernàndez‐Castillo, Noèlia;
Agnetta, Luca;
Decker, Michael;
Lluch, José M.;
Hernando, Jordi;
Loza‐Alvarez, Pablo;
Gorostiza, Pau

Publication type:

Article

A Network Meta-Analysis of Long-Acting Muscarinic Antagonist (LAMA) and Long-Acting β-Agonist (LABA) Combinations in COPD.

Published in:

Pulmonary Therapy, 2017, v. 3, n. 2, p. 297, doi. 10.1007/s41030-017-0048-0

By:

Sion, Katya;
Huisman, Eline;
Punekar, Yogesh;
Naya, Ian;
Ismaila, Afisi

Publication type:

Article

The Impact of Muscarinic Antagonism on Psychosis-Relevant Behaviors and Striatal [ 11 C] Raclopride Binding in Tau Mouse Models of Alzheimer's Disease.

Published in:

Biomedicines, 2023, v. 11, n. 8, p. 2091, doi. 10.3390/biomedicines11082091

By:

Jimenez, Heidy;
Carrion, Joseph;
Adrien, Leslie;
Wolin, Adam;
Eun, John;
Cinamon, Ezra;
Chang, Eric H.;
Davies, Peter;
Vo, An;
Koppel, Jeremy

Publication type:

Article

Investigational Treatments in Phase I and II Clinical Trials: A Systematic Review in Asthma.

Published in:

Biomedicines, 2022, v. 10, n. 9, p. 2330, doi. 10.3390/biomedicines10092330

By:

Calzetta, Luigino;
Aiello, Marina;
Frizzelli, Annalisa;
Pistocchini, Elena;
Ritondo, Beatrice Ludovica;
Rogliani, Paola;
Chetta, Alfredo

Publication type:

Article

Clozapine: past, present and future.

Published in:

World Psychiatry, 2025, v. 24, n. 2, p. 153, doi. 10.1002/wps.21335

By:

Correll, Christoph U.

Publication type:

Article

Agonist-selective activation of individual G-proteins by muscarinic receptors.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-60259-4

By:

Nelic, Dominik;
Chetverikov, Nikolai;
Hochmalová, Martina;
Diaz, Christina;
Doležal, Vladimír;
Boulos, John;
Jakubík, Jan;
Martemyanov, Kirill;
Janoušková-Randáková, Alena

Publication type:

Article

The Bronchoprotective Effects of Dual Pharmacology, Muscarinic Receptor Antagonist and β 2 Adrenergic Receptor Agonist Navafenterol in Human Small Airways.

Published in:

Cells (2073-4409), 2023, v. 12, n. 2, p. 240, doi. 10.3390/cells12020240

By:

Jude, Joseph Antony;
Dainty, Ian;
Karmacharya, Nikhil;
Jester, William;
Panettieri, Reynold

Publication type:

Article

The Combined Treatment with Chemotherapeutic Agents and the Dualsteric Muscarinic Agonist Iper-8-Naphthalimide Affects Drug Resistance in Glioblastoma Stem Cells.

Published in:

Cells (2073-4409), 2021, v. 10, n. 8, p. 1877, doi. 10.3390/cells10081877

By:

Guerriero, Claudia;
Matera, Carlo;
Del Bufalo, Donatella;
De Amici, Marco;
Conti, Luciano;
Dallanoce, Clelia;
Tata, Ada Maria

Publication type:

Article

M2 Muscarinic Receptor Activation Impairs Mitotic Progression and Bipolar Mitotic Spindle Formation in Human Glioblastoma Cell Lines.

Published in:

Cells (2073-4409), 2021, v. 10, n. 7, p. 1727, doi. 10.3390/cells10071727

By:

Di Bari, Maria;
Tombolillo, Vanessa;
Alessandrini, Francesco;
Guerriero, Claudia;
Fiore, Mario;
Asteriti, Italia Anna;
Castigli, Emilia;
Sciaccaluga, Miriam;
Guarguaglini, Giulia;
Degrassi, Francesca;
Tata, Ada Maria

Publication type:

Article

Effects of (a Combination of) the Beta 2 -Adrenoceptor Agonist Indacaterol and the Muscarinic Receptor Antagonist Glycopyrrolate on Intrapulmonary Airway Constriction.

Published in:

Cells (2073-4409), 2021, v. 10, n. 5, p. 1237, doi. 10.3390/cells10051237

By:

Maarsingh, Harm;
Oldenburger, Anouk;
Han, Bing;
Zuidhof, Annet B.;
Elzinga, Carolina R. S.;
Timens, Wim;
Meurs, Herman;
Sopi, Ramadan B.;
Schmidt, Martina;
Bagnoli, Paola

Publication type:

Article

Pharmcokinetic and pharmacodynamic considerations for the anticholinergic burden scale of drugs.

Published in:

Geriatrics & Gerontology International, 2024, v. 24, p. 81, doi. 10.1111/ggi.14706

By:

Yamada, Shizuo;
Mochizuki, Masae;
Atobe, Kazutaka;
Kato, Yoshihisa

Publication type:

Article

Markers of muscarinic deficit for individualized treatment in schizophrenia.

Published in:

Frontiers in Psychiatry, 2023, v. 13, p. 1, doi. 10.3389/fpsyt.2022.1100030

By:

Stuke, Heiner

Publication type:

Article

GPCR voltage dependence controls neuronal plasticity and behavior.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-27593-x

By:

Rozenfeld, Eyal;
Tauber, Merav;
Ben-Chaim, Yair;
Parnas, Moshe

Publication type:

Article

Multitargeting nature of muscarinic orthosteric agonists and antagonists.

Published in:

Frontiers in Physiology, 2022, v. 13, p. 1, doi. 10.3389/fphys.2022.974160

By:

Myslivecek, Jaromir

Publication type:

Article