Works matching DE "MULTIDRUG transporters"

Results: 66

Multidrug ATP-binding cassette transporters are essential for hepatic development of Plasmodium sporozoites.

Published in:

Cellular Microbiology, 2016, v. 18, n. 3, p. 369, doi. 10.1111/cmi.12517

By:

Rijpma, Sanna R.;
Velden, Maarten;
González‐Pons, Maria;
Annoura, Takeshi;
Schaijk, Ben C. L.;
Gemert, Geert‐Jan;
Heuvel, Jeroen J. M. W.;
Ramesar, Jai;
Chevalley‐Maurel, Severine;
Ploemen, Ivo H.;
Khan, Shahid M.;
Franetich, Jean‐Francois;
Mazier, Dominique;
Wilt, Johannes H.W.;
Serrano, Adelfa E.;
Russel, Frans G. M.;
Janse, Chris J.;
Sauerwein, Robert W.;
Koenderink, Jan B.;
Franke‐Fayard, Blandine M.

Publication type:

Article

Role of P-glycoprotein inhibitors in children with drug-resistant epilepsy.

Published in:

Acta Neurologica Scandinavica, 2017, v. 136, n. 6, p. 639, doi. 10.1111/ane.12778

By:

Elkhayat, H. A.;
Aly, R. H.;
Elagouza, I. A.;
El‐Kabarity, R. H.;
Galal, Y. I.

Publication type:

Article

Structural biology: First model of the entire AcrAB-TolC efflux pump.

Published in:

Nature Reviews Microbiology, 2014, v. 12, n. 6, p. 395, doi. 10.1038/nrmicro3277

By:

Kåhrström, Christina Tobin

Publication type:

Article

Structure of an engineered multidrug transporter MdfA reveals the molecular basis for substrate recognition.

Published in:

Communications Biology, 2019, v. 2, n. 1, p. N.PAG, doi. 10.1038/s42003-019-0446-y

By:

Wu, Hsin-Hui;
Symersky, Jindrich;
Lu, Min

Publication type:

Article

Complexities of a protonatable substrate in measurements of Hoechst 33342 transport by multidrug transporter LmrP.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-76943-0

By:

Swain, Brendan M.;
Guo, Dawei;
Singh, Himansha;
Rawlins, Philip B.;
McAlister, Mark;
van Veen, Hendrik W.

Publication type:

Article

Dynamic ABCG2 expression in human embryonic stem cells provides the basis for stress response.

Published in:

European Biophysics Journal, 2013, v. 42, n. 2/3, p. 169, doi. 10.1007/s00249-012-0838-0

By:

Erdei, Zsuzsa;
Sarkadi, Balázs;
Brózik, Anna;
Szebényi, Kornélia;
Várady, György;
Makó, Veronika;
Péntek, Adrienn;
Orbán, Tamás;
Apáti, Ágota

Publication type:

Article

Combined QSAR and molecule docking studies on predicting P-glycoprotein inhibitors.

Published in:

Journal of Computer-Aided Molecular Design, 2013, v. 27, n. 12, p. 1067, doi. 10.1007/s10822-013-9697-8

By:

Tan, Wen;
Mei, Hu;
Chao, Li;
Liu, Tengfei;
Pan, Xianchao;
Shu, Mao;
Yang, Li

Publication type:

Article

Structural basis for the inhibition of bacterial multidrug exporters.

Published in:

Nature, 2013, v. 500, n. 7460, p. 102, doi. 10.1038/nature12300

By:

Nakashima, Ryosuke;
Sakurai, Keisuke;
Yamasaki, Seiji;
Hayashi, Katsuhiko;
Nagata, Chikahiro;
Hoshino, Kazuki;
Onodera, Yoshikuni;
Nishino, Kunihiko;
Yamaguchi, Akihito

Publication type:

Article

Characterization of the Gene Expression Profile of Human Hippocampus in Mesial Temporal Lobe Epilepsy with Hippocampal Sclerosis.

Published in:

Epilepsy Research & Treatment, 2011, p. 1, doi. 10.1155/2011/758407

By:

Lachos, Julio;
Zattoni, Michela;
Wieser, Heinz-Gregor;
Fritschy, Jean-Marc;
Langmann, Thomas;
Schmitz, Gerd;
Errede, Mariella;
Virgintino, Daniela;
Yonekawa, Yasuhiro;
Frei, Karl

Publication type:

Article

Jump into a New Fold—A Homology Based Model for the ABCG2/BCRP Multidrug Transporter.

Published in:

PLoS ONE, 2016, v. 11, n. 10, p. 1, doi. 10.1371/journal.pone.0164426

By:

László, Laura;
Sarkadi, Balázs;
Hegedűs, Tamás

Publication type:

Article

Functional Cooperativity between ABCG4 and ABCG1 Isoforms.

Published in:

PLoS ONE, 2016, v. 11, n. 5, p. 1, doi. 10.1371/journal.pone.0156516

By:

Hegyi, Zoltán;
Homolya, László

Publication type:

Article

In vitro and in silico evaluation of P‐glycoprotein inhibition through <sup>99m</sup>Tc‐methoxyisobutylisonitrile uptake.

Published in:

Chemical Biology & Drug Design, 2019, v. 93, n. 3, p. 283, doi. 10.1111/cbdd.13411

By:

Hosseini Balef, Seyed Sajad;
Piramoon, Majid;
Hosseinimehr, Seyed Jalal;
Irannejad, Hamid

Publication type:

Article

Study of the degradation of a multidrug transporter using a non-radioactive pulse chase method.

Published in:

Analytical & Bioanalytical Chemistry, 2016, v. 408, n. 27, p. 7745, doi. 10.1007/s00216-016-9871-7

By:

Chai, Qian;
Webb, Stacy;
Wang, Zhaoshuai;
Dutch, Rebecca;
Wei, Yinan

Publication type:

Article

Non-equivalent roles of two periplasmic subunits in the function and assembly of triclosan pump TriABC from P seudomonas aeruginosa.

Published in:

Molecular Microbiology, 2015, v. 98, n. 2, p. 343, doi. 10.1111/mmi.13124

By:

Weeks, Jon W.;
Nickels, Logan M.;
Ntreh, Abigail T.;
Zgurskaya, Helen I.

Publication type:

Article

A single-component multidrug transporter of the major facilitator superfamily is part of a network that protects E scherichia coli from bile salt stress.

Published in:

Molecular Microbiology, 2014, v. 92, n. 4, p. 872, doi. 10.1111/mmi.12597

By:

Paul, Stephanie;
Alegre, Kamela O.;
Holdsworth, Scarlett R.;
Rice, Matthew;
Brown, James A.;
McVeigh, Paul;
Kelly, Sharon M.;
Law, Christopher J.

Publication type:

Article

Characterization of new, efficient Mycobacterium tuberculosis topoisomerase-I inhibitors and their interaction with human ABC multidrug transporters.

Published in:

PLoS ONE, 2018, v. 13, n. 9, p. 1, doi. 10.1371/journal.pone.0202749

By:

Temesszentandrási-Ambrus, Csilla;
Tóth, Szilárd;
Verma, Rinkee;
Bánhegyi, Péter;
Szabadkai, István;
Baska, Ferenc;
Szántai-Kis, Csaba;
Hartkoorn, Ruben C.;
Lingerfelt, Mary A.;
Sarkadi, Balázs;
Szakács, Gergely;
Őrfi, László;
Nagaraja, Valakunja;
Ekins, Sean;
Telbisz, Ágnes

Publication type:

Article

The multidrug transporter ABCG2: still more questions than answers.

Published in:

Biochemical Society Transactions, 2016, v. 44, n. 3, p. 824, doi. 10.1042/BST20160014

By:

Horsey, Aaron J.;
Cox, Megan H.;
Sarwat, Sunehera;
Kerr, Ian D.

Publication type:

Article

Oral Session II‐A (OII‐A) Transporters Across the Therapeutic Spectrum 10:30 am – 11:45 am.

Published in:: Clinical Pharmacology & Therapeutics, 2014, v. 95, p. S57, doi. 10.1038/clpt.2013.248
Publication type:: Article

The UCSF-FDA TransPortal: A Public Drug Transporter Database.

Published in:

Clinical Pharmacology & Therapeutics, 2012, v. 92, n. 5, p. 545, doi. 10.1038/clpt.2012.44

By:

Morrissey, K M;
Wen, C C;
Johns, S J;
Zhang, L;
Huang, S-M;
Giacomini, K M

Publication type:

Article

Prediction of Transporter-Mediated Drug-Drug Interactions Using Endogenous Compounds.

Published in:

Clinical Pharmacology & Therapeutics, 2012, v. 92, n. 5, p. 546, doi. 10.1038/clpt.2012.145

By:

Fromm, M F

Publication type:

Article

Drug Trafficking: Recent Advances in Therapeutics and Disease.

Published in:

Clinical Pharmacology & Therapeutics, 2012, v. 92, n. 5, p. 531, doi. 10.1038/clpt.2012.167

By:

Sprowl, J A;
Sparreboom, A

Publication type:

Article

N-Methylnicotinamide Is an Endogenous Probe for Evaluation of Drug-Drug Interactions Involving Multidrug and Toxin Extrusions (MATE1 and MATE2-K).

Published in:

Clinical Pharmacology & Therapeutics, 2012, v. 92, n. 5, p. 635, doi. 10.1038/clpt.2012.138

By:

Ito, S;
Kusuhara, H;
Kumagai, Y;
Moriyama, Y;
Inoue, K;
Kondo, T;
Nakayama, H;
Horita, S;
Tanabe, K;
Yuasa, H;
Sugiyama, Y

Publication type:

Article

A Step Closer to Personalized Chemotherapy: Consideration of the Influence of Genetic Variation in Hepatic Uptake Transporters on the Metabolism of CYP3A Substrates.

Published in:

Clinical Pharmacology & Therapeutics, 2012, v. 92, n. 5, p. 551, doi. 10.1038/clpt.2012.165

By:

Benet, L Z

Publication type:

Article

The interaction of bortezomib with multidrug transporters: implications for therapeutic applications in advanced multiple myeloma and other neoplasias.

Published in:

Cancer Chemotherapy & Pharmacology, 2013, v. 71, n. 5, p. 1357, doi. 10.1007/s00280-013-2136-7

By:

O'Connor, Robert;
Ooi, Melissa;
Meiller, Justine;
Jakubikova, Jana;
Klippel, Steffen;
Delmore, Jake;
Richardson, Paul;
Anderson, Kenneth;
Clynes, Martin;
Mitsiades, Constantine;
O'Gorman, Peter

Publication type:

Article

The multidrug transporter Pdr5 on the 25th anniversary of its discovery: an important model for the study of asymmetric ABC transporters.

Published in:

Biochemical Journal, 2015, v. 467, n. 3, p. 353, doi. 10.1042/BJ20150042

By:

Golin, John;
Ambudkar, Suresh V.

Publication type:

Article

Structure and mechanism of a redesigned multidrug transporter from the Major Facilitator Superfamily.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-60332-8

By:

Wu, Hsin-Hui;
Symersky, Jindrich;
Lu, Min

Publication type:

Article

Probing the solution structure of the E. coli multidrug transporter MdfA using DEER distance measurements with nitroxide and Gd(III) spin labels.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-48694-0

By:

Yardeni, Eliane H.;
Bahrenberg, Thorsten;
Stein, Richard A.;
Mishra, Smriti;
Zomot, Elia;
Graham, Bim;
Tuck, Kellie L.;
Huber, Thomas;
Bibi, Eitan;
Mchaourab, Hassane S.;
Goldfarb, Daniella

Publication type:

Article

Generation of multidrug resistant human tissues by overexpression of the ABCG2 multidrug transporter in embryonic stem cells.

Published in:

PLoS ONE, 2018, v. 13, n. 4, p. 1, doi. 10.1371/journal.pone.0194925

By:

Erdei, Zsuzsa;
Schamberger, Anita;
Török, György;
Szebényi, Kornélia;
Várady, György;
Orbán, Tamás I.;
Homolya, László;
Sarkadi, Balázs;
Apáti, Ágota

Publication type:

Article

The reliability of molecular dynamics simulations of the multidrug transporter P-glycoprotein in a membrane environment.

Published in:

PLoS ONE, 2018, v. 13, n. 1, p. 1, doi. 10.1371/journal.pone.0191882

By:

Condic-Jurkic, Karmen;
Subramanian, Nandhitha;
Mark, Alan E.;
O’Mara, Megan L.

Publication type:

Article

A new fluorescent dye accumulation assay for parallel measurements of the ABCG2, ABCB1 and ABCC1 multidrug transporter functions.

Published in:

PLoS ONE, 2018, v. 13, n. 1, p. 1, doi. 10.1371/journal.pone.0190629

By:

Szabó, Edit;
Türk, Dóra;
Telbisz, Ágnes;
Kucsma, Nóra;
Horváth, Tamás;
Szakács, Gergely;
Homolya, László;
Sarkadi, Balázs;
Várady, György

Publication type:

Article

Heat shock factor-1 knockout enhances cholesterol 7α-hydroxylase (CYP7A1) and multidrug transporter (MDR1) gene expressions to attenuate atherosclerosis.

Published in:

Cardiovascular Research, 2016, v. 111, n. 1, p. 74, doi. 10.1093/cvr/cvw094

By:

Krishnamurthy, Karthikeyan;
Glaser, Shannon;
Alpini, Gianfranco D.;
Cardounel, Arturo J.;
Zhenguo Liu;
Ilangovan, Govindasamy

Publication type:

Article

A key structural domain of the Candida albicans Mdr1 protein.

Published in:

Biochemical Journal, 2012, v. 445, n. 3, p. 313, doi. 10.1042/BJ20120190

By:

MANDAL, Ajeet;
KUMAR, Antresh;
SINGH, Ashutosh;
LYNN, Andrew M.;
KAPOOR, Khyati;
PRASAD, Rajendra

Publication type:

Article

Molecular characterization of the citrate transporter gene TaMATE1 and expression analysis of upstream genes involved in organic acid transport under Al stress in bread wheat (Triticum aestivum).

Published in:

Physiologia Plantarum, 2014, v. 152, n. 3, p. 441, doi. 10.1111/ppl.12179

By:

Garcia‐Oliveira, Ana Luísa;
Martins‐Lopes, Paula;
Tolrá, Roser;
Poschenrieder, Charlotte;
Tarquis, Marta;
Guedes‐Pinto, Henrique;
Benito, César

Publication type:

Article

Bacillus cereus efflux protein BC3310 - a multidrug transporter of the unknown major facilitator family, UMF-2.

Published in:

Frontiers in Microbiology, 2015, v. 6, p. 1, doi. 10.3389/fmicb.2015.01063

By:

Kroeger, Jasmin K.;
Hassan, Karl;
Vörös, Aniko;
Simm, Roger;
Saidijam, Massoud;
Bettaney, Kim E.;
Bechthold, Andreas;
Paulsen, Ian T.;
Henderson, Peter J. F.;
Kolstø, Anne-Brit;
Von Wright, Atte;
Debabov, Dmitri

Publication type:

Article

Substrate binding accelerates the conformational transitions and substrate dissociation in multidrug efflux transporter AcrB.

Published in:

Frontiers in Microbiology, 2015, p. 1, doi. 10.3389/fmicb.2015.00302

By:

Beibei Wang;
Jingwei Weng;
Wenning Wang

Publication type:

Article

Mechanism of coupling drug transport reactions located in two different membranes.

Published in:

Frontiers in Microbiology, 2015, v. 6, p. 1, doi. 10.3389/fmicb.2015.00100

By:

Zgurskaya, Helen I.;
Weeks, Jon W.;
Ntreh, Abigail T.;
Nickels, Logan M.;
Wolloscheck, David

Publication type:

Article

Overexpression of Efflux Pump in Multiresistant Pseudomonas aeruginosa: How You Will Discover and Treat It?

Published in:

Infection & Chemotherapy, 2015, v. 47, n. 2, p. 142, doi. 10.3947/ic.2015.47.2.142

By:

Sun Hoe Koo

Publication type:

Article

Clinical Aspects of Transporter‐Mediated Drug–Drug Interactions.

Published in:

Clinical Pharmacology & Therapeutics, 2019, v. 105, n. 6, p. 1386, doi. 10.1002/cpt.1360

By:

Gessner, Arne;
König, Jörg;
Fromm, Martin F.

Publication type:

Article

Exploring Configuration Space and Path Space of Biomolecules Using Enhanced Sampling Techniques—Searching for Mechanism and Kinetics of Biomolecular Functions.

Published in:

International Journal of Molecular Sciences, 2018, v. 19, n. 10, p. 3177, doi. 10.3390/ijms19103177

By:

Fujisaki, Hiroshi;
Moritsugu, Kei;
Matsunaga, Yasuhiro

Publication type:

Article

Plant Flavonoids--Biosynthesis, Transport and Involvement in Stress Responses.

Published in:

International Journal of Molecular Sciences, 2013, v. 14, n. 7, p. 14950, doi. 10.3390/ijms140714950

By:

Petrussa, Elisa;
Braidot, Enrico;
Zancani, Marco;
Peresson, Carlo;
Bertolini, Alberto;
Patui, Sonia;
Vianello, Angelo

Publication type:

Article

Prediction of binding affinities of different bile acids towards multidrug transporters in Lactobacillus acidophilus NCFM - a pharmacoinformatic approach.

Published in:

Macedonian Pharmaceutical Bulletin / Makedonsko Farmacevtski Bilten, 2016, v. 62, p. 565

By:

Ðanić, Maja;
Pavlović, Nebojša;
Stanimirov, Bojan;
Stojančević, Tijana;
Kon, Svetlana Goločorbin;
Mikov, Momir

Publication type:

Article

Relationship of AcrAB-TolC efflux pump and its regulatory gene mutation with fluoroquinolones resistance by Shigella. spp.

Published in:

Tianjin Medical Journal, 2015, v. 43, n. 4, p. 404, doi. 10.11958/j.issn.0253-9896.2015.04.019

By:

YANG Xian;
DONG Lijuan;
QI Wei;
CHENG Yuqian;
LYU Xing;
LIANG Fan

Publication type:

Article

Characterizing the binding interactions between P-glycoprotein and eight known cardiovascular transport substrates.

Published in:

Pharmacology Research & Perspectives, 2015, v. 3, n. 2, p. n/a, doi. 10.1002/prp2.114

By:

Jagodinsky, Justin C.;
Akgun, Ugur

Publication type:

Article

Detection of heterozygous MDR1 nt230(del4) mutation in a mixed-breed dog: case report of possible doxorubicin toxicosis.

Published in:

Veterinary Medicine: Research & Reports, 2013, v. 4, p. 35, doi. 10.2147/VMRR.S41066

By:

Mitie Monobe, Marina;
Lunsford, Kari V.;
Pessoa Araújo Jr., João;
Bulla, Camilo

Publication type:

Article

A subgroup of MATE transporter genes regulates hypocotyl cell elongation in Arabidopsis.

Published in:

Journal of Experimental Botany, 2015, v. 66, n. 20, p. 6327, doi. 10.1093/jxb/erv344

By:

Rui Wang;
Xiayan Liu;
Shuang Liang;
Qing Ge;
Yuanfeng Li;
Jingxia Shao;
Yafei Qi;
Lijun An;
Fei Yu

Publication type:

Article

Export of Salicylic Acid from the Chloroplast Requires the Multidrug and Toxin Extrusion-Like Transporter EDS5.

Published in:

Plant Physiology, 2013, v. 162, n. 4, p. 1815, doi. 10.1104/pp.113.218156

By:

Serrano, Mario;
Wang, Bangjun;
Aryal, Bibek;
Garcion, Christophe;
Abou-Mansour, Eliane;
Heck, Silvia;
Geisler, Markus;
Mauch, Felix;
Nawrath, Christiane;
Métraux, Jean-Pierre

Publication type:

Article

Inhibition of p38 mitogen-activated protein kinase signaling reduces multidrug transporter activity and anti-epileptic drug resistance in refractory epileptic rats.

Published in:

Journal of Neurochemistry, 2016, v. 136, n. 5, p. 1096, doi. 10.1111/jnc.13498

By:

Shao, Yiye;
Wang, Cuicui;
Hong, Zhen;
Chen, Yinghui

Publication type:

Article

MexEF-OprN multidrug efflux pump transporter negatively controls N-acyl-homoserine lactone accumulation in pseudomonas syringae pv. Tabaci 6605.

Published in:

Molecular Genetics & Genomics, 2018, v. 293, n. 4, p. 907, doi. 10.1007/s00438-018-1430-9

By:

Sawada, Takahiro;
Eguchi, Miho;
Asaki, Seiya;
Kashiwagi, Ryota;
Shimomura, Kousuke;
Taguchi, Fumiko;
Matsui, Hidenori;
Yamamoto, Mikihiro;
Noutoshi, Yoshiteru;
Toyoda, Kazuhiro;
Ichinose, Yuki

Publication type:

Article

Dynamic interplay of multidrug transporters with TolC for isoprenol tolerance in Escherichia coli.

Published in:

Scientific Reports, 2015, p. 16505, doi. 10.1038/srep16505

By:

Wang, Chonglong;
Yang, Liyang;
Shah, Asad Ali;
Choi, Eui-Sung;
Kim, Seon-Won

Publication type:

Article

Combinatorial Pharmacophore Modeling of Multidrug and Toxin Extrusion Transporter 1 Inhibitors: a Theoretical Perspective for Understanding Multiple Inhibitory Mechanisms.

Published in:

Scientific Reports, 2015, p. 13684, doi. 10.1038/srep13684

By:

Xu, Yuan;
Liu, Xian;
Wang, Yulan;
Zhou, Nannan;
Peng, Jianlong;
Gong, Likun;
Ren, Jing;
Luo, Cheng;
Luo, Xiaomin;
Jiang, Hualiang;
Chen, Kaixian;
Zheng, Mingyue

Publication type:

Article