Works about MTOR protein

Results: 1705

Antifibrotic effects of luteolin on hepatic stellate cells and liver fibrosis by targeting AKT/ mTOR/p70S6K and TGFβ/Smad signalling pathways.

Published in:

Liver International, 2015, v. 35, n. 4, p. 1222, doi. 10.1111/liv.12638

By:

Li, Jie;
Li, Xingxia;
Xu, Weiheng;
Wang, Shaozhan;
Hu, Zhenlin;
Zhang, Qing;
Deng, Xing;
Wang, Jing;
Zhang, Junping;
Guo, Cheng

Publication type:

Article

Hyaluronic Acid-Based Hydrogels Enable Rod Photoreceptor Survival and Maturation In Vitro through Activation of the mTOR Pathway.

Published in:

Advanced Functional Materials, 2016, v. 26, n. 12, p. 1975, doi. 10.1002/adfm.201504024

By:

Mitrousis, Nikolaos;
Tam, Roger Y.;
Baker, Alexander E. G.;
van der Kooy, Derek;
Shoichet, Molly S.

Publication type:

Article

Elevated levels of p-Mnk1, p-eIF4E and p-p70S6K proteins are associated with tumor recurrence and poor prognosis in astrocytomas.

Published in:

Journal of Neuro-Oncology, 2017, v. 131, n. 3, p. 485, doi. 10.1007/s11060-016-2327-2

By:

Fan, Weibing;
Wang, Weiyuan;
Mao, Xinfa;
Chu, Shuzhou;
Feng, Juan;
Xiao, Desheng;
Zhou, Jianhua;
Fan, Songqing

Publication type:

Article

Specific inhibition of mTOR pathway induces anti-proliferative effect and decreases the hormone secretion in cultured pituitary adenoma cells.

Published in:

Journal of Neuro-Oncology, 2015, v. 125, n. 1, p. 79, doi. 10.1007/s11060-015-1895-x

By:

Xie, Rong;
He, Wen-Qiang;
Shen, Ming;
Shou, Xue-Fei;
Wang, Yong-Fei;
Bao, Wei-Min;
Zhao, Yao

Publication type:

Article

Combined treatment by octreotide and everolimus: Octreotide enhances inhibitory effect of everolimus in aggressive meningiomas.

Published in:

Journal of Neuro-Oncology, 2015, v. 124, n. 1, p. 33, doi. 10.1007/s11060-015-1812-3

By:

Graillon, Thomas;
Defilles, Céline;
Mohamed, Amira;
Lisbonis, Christophe;
Germanetti, Anne-Laure;
Chinot, Olivier;
Figarella-Branger, Dominique;
Roche, Pierre-Hugues;
Adetchessi, Tarek;
Fuentes, Stéphane;
Metellus, Philippe;
Dufour, Henry;
Enjalbert, Alain;
Barlier, Anne

Publication type:

Article

Mst1 regulates glioma cell proliferation via the AKT/mTOR signaling pathway.

Published in:

Journal of Neuro-Oncology, 2015, v. 121, n. 2, p. 279, doi. 10.1007/s11060-014-1654-4

By:

Chao, Yuewen;
Wang, Yan;
Liu, Xuejiao;
Ma, Peng;
Shi, Yi;
Gao, Jian;
Shi, Qiong;
Hu, Jinxia;
Yu, Rutong;
Zhou, Xiuping

Publication type:

Article

Preclinical evaluation of the combination of mTOR and proteasome inhibitors with radiotherapy in malignant peripheral nerve sheath tumors.

Published in:

Journal of Neuro-Oncology, 2014, v. 118, n. 1, p. 83, doi. 10.1007/s11060-014-1422-5

By:

Yamashita, A.;
Baia, G.;
Ho, J.;
Velarde, E.;
Wong, J.;
Gallia, G.;
Belzberg, A.;
Kimura, E.;
Riggins, G.

Publication type:

Article

EGF signalling and rapamycin-mediated mTOR inhibition in glioblastoma multiforme evaluated by phospho-specific flow cytometry.

Published in:

Journal of Neuro-Oncology, 2013, v. 112, n. 1, p. 49, doi. 10.1007/s11060-012-1035-9

By:

Cornez, Isabelle;
Joel, Mrinal;
Taskén, Kjetil;
Langmoen, Iver;
Glover, Joel;
Berge, Torunn

Publication type:

Article

Medium‐Chain Triglycerides Supplementation Protects Epilepsy‐Associated Behavioral Impairments in a Mouse Model.

Published in:

Journal of Biochemical & Molecular Toxicology, 2025, v. 39, n. 4, p. 1, doi. 10.1002/jbt.70213

By:

Kumar, Amit;
Kumari, Savita;
Dhiman, Poonam;
Singh, Damanpreet

Publication type:

Article

Astaxanthin‐S‐Allyl Cysteine Ester Protects Pancreatic β‐Cell From Glucolipotoxicity by Suppressing Oxidative Stress, Endoplasmic Reticulum Stress and mTOR Pathway Dysregulation.

Published in:

Journal of Biochemical & Molecular Toxicology, 2024, v. 38, n. 12, p. 1, doi. 10.1002/jbt.70058

By:

Sakayanathan, Penislusshiyan;
Loganathan, Chitra;
Thayumanavan, Palvannan

Publication type:

Article

Sulfamethizole attenuates poloxamer 407‐induced atherosclerotic neointima formation via inhibition of mTOR in C57BL/6 mice.

Published in:

Journal of Biochemical & Molecular Toxicology, 2023, v. 37, n. 5, p. 1, doi. 10.1002/jbt.23322

By:

Solanki, Ankita;
Savla, Shreya R.;
Borkar, Maheshkumar R.;
Bhatt, Lokesh K.

Publication type:

Article

ROR1‐AS1 knockdown inhibits growth and invasion and promotes apoptosis in NSCLC cells by suppression of the PI3K/Akt/mTOR pathway.

Published in:

Journal of Biochemical & Molecular Toxicology, 2021, v. 35, n. 5, p. 1, doi. 10.1002/jbt.22726

By:

Li, Fengbo;
Gu, Fengming;
Li, Qian;
Zhai, Chaoshuan;
Gong, Rui;
Zhu, Xuezhuan

Publication type:

Article

mTOR-inhibitor treatment of metastatic renal cell carcinoma: contribution of Choi and modified Choi criteria assessed in 2D or 3D to evaluate tumor response.

Published in:

2016

By:

Lamuraglia, M.;
Raslan, S.;
Elaidi, R.;
Oudard, S.;
Escudier, B.;
Slimane, K.;
Penna, R.;
Wagner, M.;
Lucidarme, O.;
Penna, R Renard

Publication type:

journal article

The skeletal muscle fiber: a mechanically sensitive cell.

Published in:

2019

By:

Olsen, Luke A.;
Nicoll, Justin X.;
Fry, Andrew C.

Publication type:

journal article

Physiological function of FKBP12, a primary target of rapamycin/FK506: a newly identified role in transcription of ribosomal protein genes in yeast.

Published in:

Current Genetics, 2021, v. 67, n. 3, p. 383, doi. 10.1007/s00294-020-01142-3

By:

Kasahara, Koji

Publication type:

Article

Understanding the intracellular effects of yeast extract on the enhancement of Fc-fusion protein production in Chinese hamster ovary cell culture.

Published in:

Applied Microbiology & Biotechnology, 2015, v. 99, n. 20, p. 8429, doi. 10.1007/s00253-015-6789-5

By:

Hu, Dongdong;
Sun, Yating;
Liu, Xuping;
Liu, Jintao;
Zhang, Xintao;
Zhao, Liang;
Wang, Haibin;
Tan, Wen-Song;
Fan, Li

Publication type:

Article

Effects of Fluoride on the Expression of Beclin1 and mTOR in Ameloblasts.

Published in:

Cells Tissues Organs, 2015, v. 200, n. 6, p. 405, doi. 10.1159/000441052

By:

Lei, Shuang;
Zhang, Ying;
Zhang, Kaiqiang;
Li, Jian;
Liu, Lu

Publication type:

Article

ATF6 activation promotes tumorigenesis and drug resistance in diffuse large B-cell lymphoma (DLBCL) by regulating the mTOR/S6K signaling pathway.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02264-1

By:

Su, Shuang;
Wu, Lili;
Huang, Chen;
He, Cuiying;
Wang, Lianjing;
Li, Weijing;
Liu, Wei;
Liu, Lihong

Publication type:

Article

A Mini-Review on the Insight into the Effect of Natural and Synthetic α,β-Unsaturated Carbonyl-Containing Compounds on PI3K/AKT/mTOR Signaling Pathways to Treat Breast Cancer.

Published in:

Journal of Computational Biophysics & Chemistry, 2022, v. 21, n. 6, p. 611, doi. 10.1142/S2737416522300024

By:

Voon, Kelvin Wong Khai;
Gazali, Ahmad Mahfuz;
Zamri, Normaiza;
Rullah, Kamal;
Aluwi, Mohd Fadhlizil Fasihi Mohd

Publication type:

Article

A study of the correlation between the serum Latexin levels and the mTORC subunits Raptor and Rictor in the molecular pathogenesis of chronic lymphocytic leukemia.

Published in:

Medicine Science, 2021, v. 10, n. 2, p. 511, doi. 10.5455/medscience.2021.02.067

By:

Pektas, Gokhan;
Karakus, Volkan;
Cetin, Deniz;
Edgunlu, Tuba Dogan

Publication type:

Article

Phosphatidic acid directly activates mTOR and then regulates SREBP to promote ganoderic acid biosynthesis under heat stress in Ganoderma lingzhi.

Published in:

Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-07225-y

By:

Liu, Yong-Nan;
Chen, Yu-Lin;
Zhang, Zi-Juan;
Wu, Feng-Yuan;
Wang, Hao-Jin;
Wang, Xiao-Ling;
Liu, Gao-Qiang

Publication type:

Article

Effects of copper sulphate and rumen-protected copper sulphate addition on growth performance, nutrient digestibility, rumen fermentation and hepatic gene expression in dairy bulls.

Published in:

Journal of Animal & Feed Sciences, 2020, v. 29, n. 4, p. 287, doi. 10.22358/jafs/130656/2020

By:

La, S.;
Wang, C.;
Liu, Q.;
Guo, G.;
Huo, W.;
Zhang, J.;
Pei, C.

Publication type:

Article

Dietary glycine supplementation activates mechanistic target of rapamycin signaling pathway in tissues of pigs with intrauterine growth restriction.

Published in:

Journal of Animal Science, 2024, v. 102, p. 1, doi. 10.1093/jas/skae141

By:

He, Wenliang;
Posey, Erin A;
Steele, Chandler C;
Savell, Jeffrey W;
Bazer, Fuller W;
Wu, Guoyao

Publication type:

Article

Increased supply of methionine during a heat-stress challenge in lactating holstein cows alters mammary tissue mTOR signaling and its response to lipopolysaccharide.

Published in:

Journal of Animal Science, 2022, v. 100, n. 8, p. 1, doi. 10.1093/jas/skac175

By:

Coleman, Danielle Nicole;
Vailati-Riboni, Mario;
Pate, Russell T;
Aboragah, Ahmad;
Luchini, Daniel;
Cardoso, Felipe C;
Loor, Juan J

Publication type:

Article

Thermal stress and selection for growth affect myogenic satellite cell lipid accumulation and adipogenic gene expression through mechanistic target of rapamycin pathway.

Published in:

Journal of Animal Science, 2022, v. 100, n. 8, p. 1, doi. 10.1093/jas/skac001

By:

Xu, Jiahui;
Strasburg, Gale M;
Reed, Kent M;
Velleman, Sandra G

Publication type:

Article

Pulsatile Administration of Leucine Promotes mTOR Signaling and Protein Synthesis in Skeletal Muscle of Continuously Fed Preterm Pigs.

Published in:

Journal of Animal Science, 2021, v. 99, p. 102, doi. 10.1093/jas/skab235.185

By:

Rudar, Marko;
Suryawan, Agus;
Nguyen, Hanh;
Stoll, Barbara;
Burrin, Douglas;
Fiorotto, Marta;
Davis, Teresa A.

Publication type:

Article

The mammalian target of rapamycin-signaling pathway in regulating metabolism and growth<sup>2</sup>.

Published in:: Journal of Animal Science, 2008, v. 86, p. E36, doi. 10.2527/jas.2007-0567
Publication type:: Article

Assessment of Mitochondrial Biogenesis and mTORC1 Signaling During Chronic Rapamycin Feeding in Male and Female Mice.

Published in:

Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2013, v. 68, n. 12, p. 1493, doi. 10.1093/gerona/glt047

By:

Drake, Joshua C.;
Peelor, Frederick F.;
Biela, Laurie M.;
Watkins, Molly K.;
Miller, Richard A.;
Hamilton, Karyn L.;
Miller, Benjamin F.

Publication type:

Article

Downregulation of Glutamate Transporter EAAT4 by Conditional Knockout of Rheb1 in Cerebellar Purkinje Cells.

Published in:

Cerebellum, 2016, v. 15, n. 3, p. 314, doi. 10.1007/s12311-015-0701-9

By:

Jiang, Nan-Wei;
Wang, De-Juan;
Xie, Ya-Jun;
Zhou, Liang;
Su, Li-Da;
Li, Huashun;
Wang, Qin-Wen;
Shen, Ying

Publication type:

Article

Clinical Significance of LINC00261 in the Pathogenesis of Pancreatic, Colorectal, Hepatocellular, and Gallbladder Cancer.

Published in:

Diseases, 2025, v. 13, n. 3, p. 89, doi. 10.3390/diseases13030089

By:

Bana, Sanjana;
Daffara, Sia;
Dagar, Aastha;
Tiwari, Ashutosh Kumar;
Medhi, Kanupriya;
Mukherjee, Sagarika;
Uttam, Vivek;
Ansari, Md Rizwan;
Tuli, Hardeep Singh;
Yadav, Vikas;
Jain, Aklank

Publication type:

Article

The Roles of Autophagy, Mitophagy, and the Akt/mTOR Pathway in the Pathogenesis of Chronic Rhinosinusitis with Nasal Polyps.

Published in:

2022

By:

Wang, Chen;
Zhou, Min-Li;
Liu, Yong-Cai;
Cheng, Ke-Jia

Publication type:

journal article

Exploring the potential of AgNPs in modulating the PI3K/AKT/mTOR pathway via miR-133a regulation in MCF-7 breast cancer cells.

Published in:

Nanomedicine Journal, 2024, v. 11, n. 1, p. 52, doi. 10.22038/NMJ.2023.75091.1824

By:

Tehrani, Mohammadjavad Hossein;
Ziamajidi, Nasrin;
Abbasalipourkabir, Roghayeh;
Barartabar, Zeinab;
Aslani, Somayeh

Publication type:

Article

Vincamine induces cytoprotective autophagy via regulation of ampk/mtor signaling pathway in gentamicin-induced hepatotoxicity and nephrotoxicity in rats.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-06355-5

By:

Abouelhamd, Alaa;
Shehata, Nourhan Elpry Mahmoud;
Abdel-Hafez, Sara Mohamed Naguib;
Abu-Baih, Dalia H.

Publication type:

Article

Exploring the efficacy of Benincasa hispida extract on obesity linked inflammatory bowel disease by integrating computational analysis and experimental validations.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-99256-6

By:

Patil, Santosh B.;
Kuvalekar, Manisha B.;
Yaraguppi, Deepak A.;
Prasanth, D. S. N. B. K.;
Halkavatagi, Sangameshwar G.;
Tennalli, Gururaj B.;
Javali, Mukhatar Ahmed;
Khan, T. M. Yunus

Publication type:

Article

Substituents introduction of methyl and methoxy functional groups on resveratrol stabilizes mTOR binding for autophagic cell death induction.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-98616-6

By:

Ei, Zin Zin;
Racha, Satapat;
Chunhacha, Preedakorn;
Yokoya, Masashi;
Moriue, Sohsuke;
Zou, Hongbin;
Chanvorachote, Pithi

Publication type:

Article

Exploring the efficacy of Benincasa hispida extract on obesity linked inflammatory bowel disease by integrating computational analysis and experimental validations.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-99256-6

By:

Patil, Santosh B.;
Kuvalekar, Manisha B.;
Yaraguppi, Deepak A.;
Prasanth, D. S. N. B. K.;
Halkavatagi, Sangameshwar G.;
Tennalli, Gururaj B.;
Javali, Mukhatar Ahmed;
Khan, T. M. Yunus

Publication type:

Article

Leptin induced GRP78 expression through the PI3K-mTOR pathway in neuronal cells.

Published in:

Scientific Reports, 2014, p. 1, doi. 10.1038/srep07096

By:

Thon, Mina;
Hosoi, Toru;
Yoshii, Michiko;
Ozawa, Koichiro

Publication type:

Article

Computational analysis to miRNAs prediction which target 3′-UTR of mTOR gene.

Published in:

Medical journal of Mashhad University of Medical Sciences, 2016, v. 59, p. 36

By:

Razaviyan, Javad;
Hadavi, Razie

Publication type:

Article

mTOR is Localized to Both the Mitochondria and Cytosol at Comparable Levels in the Heart.

Published in:

Hawaii Journal of Medicine & Public Health, 2013, v. 72, n. 9, p. 46

By:

Taitano, Genia;
Toshinori Aoyagi;
Takashi Matsui M

Publication type:

Article

Effect of fermentation on the constituents in the branches and leaves of Taxus media and non-small cell lung cancer.

Published in:

Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1449498

By:

Guo, Xing;
Wang, Rui-Sheng;
Zhang, Zhen-Ling;
Zhang, Hong-Wei;
Wang, Sheng-Chao;
Zhang, Shuai;
Wu, Ya-Ning;
Li, Ya-Jing;
Yuan, Jun

Publication type:

Article

Saponins From <italic>Paris forrestii</italic> (Takht.) H. Li Display Potent Activity Against Acute Myeloid Leukemia by Suppressing the RNF6/AKT/mTOR Signaling Pathway.

Published in:

Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.00673

By:

Lu, Qin;
He, Yuanming;
Wang, Yuehu;
Gao, Li;
Zheng, Yunjing;
Zhang, Zubin;
Cao, Biyin;
Wang, Qi;
Mao, Xinliang;
Hu, Shaoyan

Publication type:

Article

Aurora-A Induces Chemoresistance Through Activation of the AKT/mTOR Pathway in Endometrial Cancer.

Published in:

Frontiers in Oncology, 2019, p. N.PAG, doi. 10.3389/fonc.2019.00422

By:

Wu, Jun;
Cheng, Ziyun;
Xu, Xiaofeng;
Fu, Jian;
Wang, Kaiyue;
Liu, Tao;
Wu, Chan;
Kong, Xiangyi;
Yang, Qian;
Yan, Guijun;
Zhou, Huaijun

Publication type:

Article

CircRNA-100338 Is Associated With mTOR Signaling Pathway and Poor Prognosis in Hepatocellular Carcinoma.

Published in:

Frontiers in Oncology, 2019, p. N.PAG, doi. 10.3389/fonc.2019.00392

By:

Huang, Xiu-Yan;
Huang, Zi-Li;
Zhang, Ping-Bao;
Huang, Xin-Yu;
Huang, Jin;
Wang, Hong-Cheng;
Xu, Bin;
Zhou, Jian;
Tang, Zhao-You

Publication type:

Article

Early-Life Stress Alters Synaptic Plasticity and mTOR Signaling: Correlation With Anxiety-Like and Cognition-Related Behavior.

Published in:

Frontiers in Genetics, 2020, v. 11, p. N.PAG, doi. 10.3389/fgene.2020.590068

By:

Wang, Anfeng;
Zou, Xiaojuan;
Wu, Jiajia;
Ma, Qingyu;
Yuan, Naijun;
Ding, Fengmin;
Li, Xiaojuan;
Chen, Jiaxu

Publication type:

Article

PD-L1 Upregulation by the mTOR Pathway in VEGFR-TKI–Resistant Metastatic Clear Cell Renal Cell Carcinoma.

Published in:

Cancer Research & Treatment, 2023, v. 55, n. 1, p. 231, doi. 10.4143/crt.2021.1526

By:

Se Un Jeong;
Hee Sang Hwang;
Ja-Min Park;
Sun Young Yoon;
Su-Jin Shin;
Heounjeong Go;
Jae-Lyun Lee;
Gowun Jeong;
Yong Mee Cho

Publication type:

Article

Efficacy and Toxicity of Mammalian Target Rapamycin Inhibitors in Patients with Metastatic Renal Cell Carcinoma with Renal Insufficiency: The Korean Cancer Study Group GU 14-08.

Published in:

Cancer Research & Treatment, 2016, v. 48, n. 4, p. 1286, doi. 10.4143/crt.2016.018

By:

Ki Hyang Kim;
Joo Hoon Kim;
Ji Young Lee;
Hyo Song Kim;
Su Jin Heo;
Ji Hyung Kim;
Ho Young Kim;
Sun Young Rha

Publication type:

Article

Hyperglycaemia Induced by Novel Anticancer Agents: An Undesirable Complication or a Potential Therapeutic Opportunity?

Published in:

2017

By:

Shah, Rashmi;
Shah, Rashmi R

Publication type:

journal article

Essential amino acid ratios and mTOR affect lipogenic gene networks and miRNA expression in bovine mammary epithelial cells.

Published in:

Journal of Animal Science & Biotechnology, 2016, v. 7, p. 1, doi. 10.1186/s40104-016-0104-x

By:

Shanshan Li;
Hosseini, Afshin;
Danes, Marina;
Jacometo, Carolina;
Jianxin Liu;
Loor, Juan J.

Publication type:

Article

Hormone Therapy plus mTOR Inhibitors in the Treatment of Endometrial Carcinoma.

Published in:

European Endocrinology, 2013, v. 9, n. 1, p. 18, doi. 10.17925/EE.2013.09.01.18

By:

Stringer, Erica M.;
Fleming, Gini F.

Publication type:

Article

Metformin reverses multidrug resistance in human hepatocellular carcinoma Bel-7402/5-fluorouracil cells.

Published in:

2022

By:

Ling, Sunbin;
Tian, Yu;
Zhang, Haiquan;
Jia, Kaiqi;
Feng, Tingting;
Sun, Deguang;
Gao, Zhenming;
Xu, Fei;
Hou, Zhaoyuan;
Li, Yan;
Wang, Liming

Publication type:

Correction Notice