Works matching DE "MTOR protein"

Results: 1698

Daidzein Promotes the Proliferation of Porcine Mammary Epithelial Cells Through the mTOR Signaling Pathway.

Published in:

Agriculture; Basel, 2025, v. 15, n. 9, p. 930, doi. 10.3390/agriculture15090930

By:

Xu, Mengmeng;
Liu, Le;
Duan, Wenjing;
Niu, Lizhu;
Cheng, He;
Du, Chenyang;
Li, Mengyun;
Huo, Wenying;
Deng, Hongyu;
Zhou, Pan;
Chen, Wen;
Che, Long

Publication type:

Article

Virtual screening and molecular dynamics simulation study of ATP-competitive inhibitors targeting mTOR protein.

Published in:

PLoS ONE, 2025, v. 20, n. 5, p. 1, doi. 10.1371/journal.pone.0319608

By:

Jin, Mei-Yu;
Yu, Hao;
Deng, Qiong;
Wang, Zhu;
Wang, Jie-Yan;
Li, Hao-Long;
Liang, Hui

Publication type:

Article

Cardamonin suppresses mTORC1/SREBP1 through reducing Raptor and inhibits de novo lipogenesis in ovarian cancer.

Published in:

PLoS ONE, 2025, v. 20, n. 5, p. 1, doi. 10.1371/journal.pone.0322733

By:

Niu, Peiguang;
Li, Danyun;
Chen, Huajiao;
Zhu, Yanting;
Zhou, Jintuo;
Zhang, Jinhua;
Liu, Ying

Publication type:

Article

Insulin and mTOR Pathway Regulate HDAC3-Mediated Deacetylation and Activation of PGK1.

Published in:

PLoS Biology, 2015, v. 13, n. 9, p. 1, doi. 10.1371/journal.pbio.1002243

By:

Wang, Shiwen;
Jiang, Bowen;
Zhang, Tengfei;
Liu, Lixia;
Wang, Yi;
Wang, Yiping;
Chen, Xiufei;
Lin, Huaipeng;
Zhou, Lisha;
Xia, Yukun;
Chen, Leilei;
Yang, Chen;
Xiong, Yue;
Ye, Dan;
Guan, Kun-Liang

Publication type:

Article

Hyaluronic Acid-Based Hydrogels Enable Rod Photoreceptor Survival and Maturation In Vitro through Activation of the mTOR Pathway.

Published in:

Advanced Functional Materials, 2016, v. 26, n. 12, p. 1975, doi. 10.1002/adfm.201504024

By:

Mitrousis, Nikolaos;
Tam, Roger Y.;
Baker, Alexander E. G.;
van der Kooy, Derek;
Shoichet, Molly S.

Publication type:

Article

Repetitive restriction of muscle blood flow enhances mTOR signaling pathways in a rat model.

Published in:

Heart & Vessels, 2016, v. 31, n. 10, p. 1685, doi. 10.1007/s00380-016-0801-6

By:

Nakajima, Toshiaki;
Yasuda, Tomohiro;
Koide, Seiichiro;
Yamasoba, Tatsuya;
Obi, Syotaro;
Toyoda, Shigeru;
Sato, Yoshiaki;
Inoue, Teruo;
Kano, Yutaka

Publication type:

Article

Expression and prognostic significance of VEGF and mTOR pathway proteins in metastatic renal cell carcinoma patients: a prognostic immunohistochemical profile for kidney cancer patients.

Published in:

World Journal of Urology, 2017, v. 35, n. 3, p. 411, doi. 10.1007/s00345-016-1890-7

By:

Liontos, Michalis;
Trigka, Eleni-Andriana;
Korkolopoulou, Penelope;
Tzannis, Kimon;
Lainakis, Giorgos;
Koutsoukos, Konstantinos;
Kostouros, Efthymios;
Lykka, Maria;
Papandreou, Christos;
Karavasilis, Vassilis;
Christodoulou, Christos;
Papatsoris, Athanasios;
Skolarikos, Andreas;
Varkarakis, Ioannis;
Adamakis, Ioannis;
Alamanis, Christos;
Stravodimos, Konstantinos;
Mitropoulos, Dionysios;
Deliveliotis, Charalambos;
Constantinidis, Constantinos

Publication type:

Article

To combine or not combine: the role of radiotherapy and targeted agents in the treatment for renal cell carcinoma.

Published in:

World Journal of Urology, 2014, v. 32, n. 1, p. 59, doi. 10.1007/s00345-013-1068-5

By:

Weiss, Christian;
Schulze, Björn;
Ottinger, Annette;
Rödel, Claus

Publication type:

Article

The ineligible patient: how to treat patients not included in clinical studies.

Published in:

World Journal of Urology, 2014, v. 32, n. 1, p. 9, doi. 10.1007/s00345-013-1042-2

By:

Mao, Frances;
Rini, Brian

Publication type:

Article

Targeted therapy in renal cell carcinoma: moving from molecular agents to specific immunotherapy.

Published in:

World Journal of Urology, 2014, v. 32, n. 1, p. 31, doi. 10.1007/s00345-013-1033-3

By:

Bedke, Jens;
Gouttefangeas, Cécile;
Singh-Jasuja, Harpreet;
Stevanović, Stefan;
Behnes, Carl-Ludwig;
Stenzl, Arnulf

Publication type:

Article

How far is the horizon? From current targets to future drugs in advanced renal cancer.

Published in:

World Journal of Urology, 2014, v. 32, n. 1, p. 69, doi. 10.1007/s00345-013-1096-1

By:

Kruck, Stephan;
Merseburger, Axel;
Stenzl, Arnulf;
Bedke, Jens

Publication type:

Article

A case of diabetic ketoacidosis after everolimus treatment.

Published in:

2016

By:

Kubo, Fumiyo;
Takahara, Mitsuyoshi;
Yasuda, Tetsuyuki;
Shimo, Naoki;
Matsuoka, Taka-aki;
Shimomura, Iichiro

Publication type:

Letter

Leucine-enriched essential amino acids attenuate inflammation in rat muscle and enhance muscle repair after eccentric contraction.

Published in:

Amino Acids, 2016, v. 48, n. 9, p. 2145, doi. 10.1007/s00726-016-2240-1

By:

Kato, Hiroyuki;
Miura, Kyoko;
Nakano, Sayako;
Suzuki, Katsuya;
Bannai, Makoto;
Inoue, Yoshiko

Publication type:

Article

Alpha-ketoglutarate enhances milk protein synthesis by porcine mammary epithelial cells.

Published in:

Amino Acids, 2016, v. 48, n. 9, p. 2179, doi. 10.1007/s00726-016-2249-5

By:

Jiang, Qian;
He, Liuqin;
Hou, Yongqing;
Chen, Jiashun;
Duan, Yehui;
Deng, Dun;
Wu, Guoyao;
Yin, Yulong;
Yao, Kang

Publication type:

Article

Leucine supplementation is anti-atrophic during paradoxical sleep deprivation in rats.

Published in:

Amino Acids, 2016, v. 48, n. 4, p. 949, doi. 10.1007/s00726-015-2142-7

By:

Sá Souza, Helton;
Antunes, Hanna;
Dáttilo, Murilo;
Lee, Kil;
Mônico-Neto, Marcos;
Campos Giampa, Sara;
Phillips, Stuart;
Tufik, Sergio;
Mello, Marco

Publication type:

Article

Structure-activity relations of leucine derivatives reveal critical moieties for cellular uptake and activation of mTORC1-mediated signaling.

Published in:

Amino Acids, 2016, v. 48, n. 4, p. 1045, doi. 10.1007/s00726-015-2158-z

By:

Nagamori, Shushi;
Wiriyasermkul, Pattama;
Okuda, Suguru;
Kojima, Naoto;
Hari, Yoshiyuki;
Kiyonaka, Shigeki;
Mori, Yasuo;
Tominaga, Hideyuki;
Ohgaki, Ryuichi;
Kanai, Yoshikatsu

Publication type:

Article

Rag GTPase in amino acid signaling.

Published in:

Amino Acids, 2016, v. 48, n. 4, p. 915, doi. 10.1007/s00726-016-2171-x

By:

Kim, Joungmok;
Kim, Eunjung

Publication type:

Article

Leucine-induced anabolic-catabolism: two sides of the same coin.

Published in:

Amino Acids, 2016, v. 48, n. 2, p. 321, doi. 10.1007/s00726-015-2109-8

By:

Gannon, Nicholas;
Vaughan, Roger

Publication type:

Article

The role of leucine and its metabolites in protein and energy metabolism.

Published in:

Amino Acids, 2016, v. 48, n. 1, p. 41, doi. 10.1007/s00726-015-2067-1

By:

Duan, Yehui;
Li, Fengna;
Li, Yinghui;
Tang, Yulong;
Kong, Xiangfeng;
Feng, Zemeng;
Anthony, Tracy;
Watford, Malcolm;
Hou, Yongqing;
Wu, Guoyao;
Yin, Yulong

Publication type:

Article

Leucine supplementation of a chronically restricted protein and energy diet enhances mTOR pathway activation but not muscle protein synthesis in neonatal pigs.

Published in:

Amino Acids, 2016, v. 48, n. 1, p. 257, doi. 10.1007/s00726-015-2078-y

By:

Manjarín, Rodrigo;
Columbus, Daniel;
Suryawan, Agus;
Nguyen, Hanh;
Hernandez-García, Adriana;
Hoang, Nguyet-Minh;
Fiorotto, Marta;
Davis, Teresa

Publication type:

Article

Glutamine and intestinal barrier function.

Published in:

Amino Acids, 2015, v. 47, n. 10, p. 2143, doi. 10.1007/s00726-014-1773-4

By:

Wang, Bin;
Wu, Guoyao;
Zhou, Zhigang;
Dai, Zhaolai;
Sun, Yuli;
Ji, Yun;
Li, Wei;
Wang, Weiwei;
Liu, Chuang;
Han, Feng;
Wu, Zhenlong

Publication type:

Article

l-Glutamine deprivation induces autophagy and alters the mTOR and MAPK signaling pathways in porcine intestinal epithelial cells.

Published in:

Amino Acids, 2015, v. 47, n. 10, p. 2185, doi. 10.1007/s00726-014-1785-0

By:

Zhu, Yuhua;
Lin, Gang;
Dai, Zhaolai;
Zhou, Tianjiao;
Li, Tiantian;
Yuan, Taolin;
Wu, Zhenlong;
Wu, Guoyao;
Wang, Junjun

Publication type:

Article

Autophagy response: manipulating the mTOR-controlled machinery by amino acids and pathogens.

Published in:

Amino Acids, 2015, v. 47, n. 10, p. 2101, doi. 10.1007/s00726-014-1835-7

By:

Fader, Claudio;
Aguilera, Milton;
Colombo, María

Publication type:

Article

Amino acids and autophagy: their crosstalk, interplay and interlock.

Published in:

2015

By:

Hu, Chien-An;
Wu, Zhenlong;
Wang, Junjun

Publication type:

Editorial

Regulation of autophagy by amino acids and MTOR-dependent signal transduction.

Published in:

Amino Acids, 2015, v. 47, n. 10, p. 2037, doi. 10.1007/s00726-014-1765-4

By:

Meijer, Alfred;
Lorin, Séverine;
Blommaart, Edward;
Codogno, Patrice

Publication type:

Article

Chronic activation of mTOR complex 1 by branched chain amino acids and organ hypertrophy.

Published in:

Amino Acids, 2015, v. 47, n. 6, p. 1167, doi. 10.1007/s00726-015-1944-y

By:

Neishabouri, S.;
Hutson, S.;
Davoodi, J.

Publication type:

Article

Leucine-enriched essential amino acids attenuate muscle soreness and improve muscle protein synthesis after eccentric contractions in rats.

Published in:

Amino Acids, 2015, v. 47, n. 6, p. 1193, doi. 10.1007/s00726-015-1946-9

By:

Kato, Hiroyuki;
Suzuki, Hiromi;
Mimura, Masako;
Inoue, Yoshiko;
Sugita, Mayu;
Suzuki, Katsuya;
Kobayashi, Hisamine

Publication type:

Article

Key mediators of intracellular amino acids signaling to mTORC1 activation.

Published in:

Amino Acids, 2015, v. 47, n. 5, p. 857, doi. 10.1007/s00726-015-1937-x

By:

Duan, Yehui;
Li, Fengna;
Tan, Kunrong;
Liu, Hongnan;
Li, Yinghui;
Liu, Yingying;
Kong, Xiangfeng;
Tang, Yulong;
Wu, Guoyao;
Yin, Yulong

Publication type:

Article

l-Glutamine enhances enterocyte growth via activation of the mTOR signaling pathway independently of AMPK.

Published in:

Amino Acids, 2015, v. 47, n. 1, p. 65, doi. 10.1007/s00726-014-1842-8

By:

Yi, Dan;
Hou, Yongqing;
Wang, Lei;
Ouyang, Wanjin;
Long, Minhui;
Zhao, Di;
Ding, Binying;
Liu, Yulan;
Wu, Guoyao

Publication type:

Article

Arginine protects muscle cells from wasting in vitro in an mTORC1-dependent and NO-independent manner.

Published in:

Amino Acids, 2014, v. 46, n. 12, p. 2643, doi. 10.1007/s00726-014-1815-y

By:

Ham, Daniel;
Caldow, Marissa;
Lynch, Gordon;
Koopman, René

Publication type:

Article

Sepsis-induced changes in amino acid transporters and leucine signaling via mTOR in skeletal muscle.

Published in:

Amino Acids, 2014, v. 46, n. 12, p. 2787, doi. 10.1007/s00726-014-1836-6

By:

Laufenberg, Lacee;
Pruznak, Anne;
Navaratnarajah, Maithili;
Lang, Charles

Publication type:

Article

Leucine stimulates ASCT2 amino acid transporter expression in porcine jejunal epithelial cell line (IPEC-J2) through PI3K/Akt/mTOR and ERK signaling pathways.

Published in:

Amino Acids, 2014, v. 46, n. 12, p. 2633, doi. 10.1007/s00726-014-1809-9

By:

Zhang, Shihai;
Ren, Man;
Zeng, Xiangfang;
He, Pingli;
Ma, Xi;
Qiao, Shiyan

Publication type:

Article

Abundance of amino acid transporters involved in mTORC1 activation in skeletal muscle of neonatal pigs is developmentally regulated.

Published in:

Amino Acids, 2013, v. 45, n. 3, p. 523, doi. 10.1007/s00726-012-1326-7

By:

Suryawan, Agus;
Nguyen, Hanh;
Almonaci, Rosemarie;
Davis, Teresa

Publication type:

Article

Nutritionally essential amino acids and metabolic signaling in aging.

Published in:

Amino Acids, 2013, v. 45, n. 3, p. 431, doi. 10.1007/s00726-012-1438-0

By:

Dillon, E.

Publication type:

Article

Is mTOR involved in the mechanisms of the fast-acting antidepressant effects of AMPA receptor agonists?

Published in:

2013

By:

Hu, Yimin;
Liu, Xiangliu;
Shen, Jinchun

Publication type:

Letter

The Mechanism of Adaptation of Breast Cancer Cells to Hypoxia: Role of AMPK/mTOR Signaling Pathway.

Published in:

Bulletin of Experimental Biology & Medicine, 2016, v. 160, n. 4, p. 555, doi. 10.1007/s10517-016-3217-5

By:

Sorokin, D.;
Scherbakov, A.;
Yakushina, I.;
Semina, S.;
Gudkova, M.;
Krasil'nikov, M.

Publication type:

Article

Tubastatin A suppresses the proliferation of fibroblasts in epidural fibrosis through phosphatidylinositol-3-kinase/protein kinase B/mammalian target of rapamycin (PI3K/AKT/mTOR) signalling pathway.

Published in:

Journal of Pharmacy & Pharmacology, 2022, v. 74, n. 3, p. 426, doi. 10.1093/jpp/rgab106

By:

Liu, Yang;
Wang, Ruihong;
Han, Huimin;
Li, Li

Publication type:

Article

Anticancer activity of tetrandrine by inducing pro‐death apoptosis and autophagy in human gastric cancer cells.

Published in:

Journal of Pharmacy & Pharmacology, 2018, v. 70, n. 8, p. 1048, doi. 10.1111/jphp.12935

By:

Bai, Xin‐Yu;
Liu, Yuan‐Gui;
Song, Wu;
Li, Ying‐Ying;
Hou, Dong‐Shun;
Luo, Hao‐Ming;
Liu, Ping

Publication type:

Article

Neurodegenerative disease: Restoring balance in Huntington disease.

Published in:

Nature Reviews Neuroscience, 2015, v. 16, n. 2, p. 66, doi. 10.1038/nrn3906

By:

Whalley, Katherine

Publication type:

Article

تأثير تمرينات القد ارت الهوائية القصوى على بعض المؤش ارت البيوكيميائية لدى العبي كرة القدم.

Published in:

Journal of Physical Education (20736452), 2022, v. 34, n. 3, p. 405, doi. 10.37359/JOPE.V34(3)2022.1320

By:

يوسف كاظم عبد;
علي أحمد هادي

Publication type:

Article

SMAD4 mutations and cross-talk between TGF-β/IFNγ signaling accelerate rates of DNA damage and cellular senescence, resulting in a segmental progeroid syndrome—the Myhre syndrome.

Published in:

GeroScience, 2021, v. 43, n. 3, p. 1481, doi. 10.1007/s11357-020-00318-6

By:

Kandhaya-Pillai, Renuka;
Hou, Deyin;
Zhang, Jiaming;
Yang, Xiaomeng;
Compoginis, Goli;
Mori, Takayasu;
Tchkonia, Tamara;
Martin, George M.;
Hisama, Fuki M.;
Kirkland, James L.;
Oshima, Junko

Publication type:

Article

Age-dependent effects of caloric restriction on mTOR and ubiquitin-proteasome pathways in skeletal muscles.

Published in:

GeroScience, 2019, v. 41, n. 6, p. 871, doi. 10.1007/s11357-019-00109-8

By:

Chen, Chiao-Nan;
Liao, Yi-Hung;
Tsai, Shiow-Chwen;
Thompson, LaDora V.

Publication type:

Article

The AMPK Agonist PT1 and mTOR Inhibitor 3HOI-BA-01 Protect Cardiomyocytes After Ischemia Through Induction of Autophagy.

Published in:

2016

By:

Huang, Ling;
Dai, Kai;
Chen, Manhua;
Zhou, Wenping;
Wang, Xiaoling;
Chen, Jing;
Zhou, Wei

Publication type:

journal article

Effects of copper sulphate and rumen-protected copper sulphate addition on growth performance, nutrient digestibility, rumen fermentation and hepatic gene expression in dairy bulls.

Published in:

Journal of Animal & Feed Sciences, 2020, v. 29, n. 4, p. 287, doi. 10.22358/jafs/130656/2020

By:

La, S.;
Wang, C.;
Liu, Q.;
Guo, G.;
Huo, W.;
Zhang, J.;
Pei, C.

Publication type:

Article

The mammalian target of rapamycin-signaling pathway in regulating metabolism and growth<sup>2</sup>.

Published in:: Journal of Animal Science, 2008, v. 86, p. E36, doi. 10.2527/jas.2007-0567
Publication type:: Article

Mao-B elevation decreases parkin's ability to efficiently clear damaged mitochondria: protective effects of rapamycin.

Published in:

Free Radical Research, 2012, v. 46, n. 8, p. 1011, doi. 10.3109/10715762.2012.662277

By:

Siddiqui, Almas;
Hanson, Ingrid;
Andersen, Julie K.

Publication type:

Article

Foam dressing and micropower vacuum dressing promote diabetic foot ulcer wound healing by activating the PI3K/AKT/mTOR pathway in rats.

Published in:

Journal of Biomaterials Applications, 2024, v. 39, n. 1, p. 40, doi. 10.1177/08853282241248780

By:

Chen, Cunren;
Ou, Qianying;
Chen, Kaining;
Liang, Changli;
Zeng, Xiaocui;
Lin, Danhong;
Lin, Lu

Publication type:

Article

The concerted action of oncogenic driver mutations directs global translation in intestinal epithelial cells.

Published in:

Molecular & Cellular Oncology, 2021, v. 8, n. 4, p. 1, doi. 10.1080/23723556.2021.1879614

By:

Smit, Wouter;
Heijmans, Jarom

Publication type:

Article

A mTORC1-mediated cyst(e)ine sensing mechanism governing GPX4 synthesis and ferroptosis.

Published in:

Molecular & Cellular Oncology, 2021, v. 8, n. 3, p. 1, doi. 10.1080/23723556.2021.1919006

By:

Yan, Yuelong;
Lei, Guang;
Gan, Boyi

Publication type:

Article

Regulation of nuclear mTORC1.

Published in:

Molecular & Cellular Oncology, 2021, v. 8, n. 3, p. 1, doi. 10.1080/23723556.2021.1896348

By:

Zhou, Xin;
Zhong, Yanghao;
Zhang, Jin

Publication type:

Article