Works matching DE "MTOR inhibitors"

Results: 720

Systemic Treatment of Locally Advanced or Metastatic Non-Clear Cell Renal Cell Carcinoma.

Published in:

Cancers, 2025, v. 17, n. 9, p. 1527, doi. 10.3390/cancers17091527

By:

Vento, Joseph;
Zhang, Tian;
Kapur, Payal;
Hammers, Hans;
Brugarolas, James;
Qin, Qian

Publication type:

Article

Dynamic regulation of murine RNA polymerase III transcription during heat shock stress.

Published in:

Genetics, 2025, v. 230, n. 1, p. 1, doi. 10.1093/genetics/iyaf042

By:

Nguyen, Thomas F;
Kwan, James Z J;
Mitchell, Jennifer E;
Cui, Jieying H;
Teves, Sheila S

Publication type:

Article

Corrigendum: Targeting the PI3K/AKT/mTOR pathway in lung cancer: mechanisms and therapeutic targeting.

Published in:

2025

By:

Qiang, Min;
Chen, Zhe;
Liu, Hongyang;
Dong, Junxue;
Gong, Kejian;
Zhang, Xinjun;
Huo, Peng;
Zhu, Jingjun;
Shao, Yifeng;
Ma, Jinazun;
Zhang, Bowei;
Liu, Wei;
Tang, Mingbo

Publication type:

Correction Notice

Phénomène de Kasabach-Meritt compliquant un hémangioendothéliome kaposiforme : succès d'un traitement par évérolimus en thérapie combine.

Published in:

2025

By:

Souad, Choukri;
Hanane, Baybay;
Sara, Elloudi;
Meryem, Soughi;
Zakia, Douhi;
Zahra, Mernissi Fatima

Publication type:

Case Study

Targeting the PI3K/AKT/mTOR pathway in lung cancer: mechanisms and therapeutic targeting.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1516583

By:

Qiang, Min;
Chen, Zhe;
Liu, Hongyang;
Dong, Junxue;
Gong, Kejian;
Zhang, Xinjun;
Huo, Peng;
Zhu, Jingjun;
Shao, Yifeng;
Ma, Jinazun;
Zhang, Bowei;
Liu, Wei;
Tang, Mingbo

Publication type:

Article

mTOR inhibitor in the treatment of TFE-positive advanced maligmnant PEComa of the uterus: a case report and literature review.

Published in:

Ginekologia Polska, 2025, v. 96, n. 3, p. 206, doi. 10.5603/gpl.99247

By:

Yaoxiang Zhong;
Haikun Yang

Publication type:

Article

Evaluating Oncogenic Drivers and Therapeutic Potential of the PI3K/AKT/mTOR Pathway in Hepatocellular Carcinoma: An Overview of Clinical Trials.

Published in:

Biocell, 2025, v. 49, n. 4, p. 539, doi. 10.32604/biocell.2025.059970

By:

Khorasani, Ayda Baghery Saghchy;
Delshad, Mahda;
Sanaei, Mohammad-Javad;
Pourbagheri-Sigaroodi, Atieh;
Pirsalehi, Ali;
Bashash, Davood

Publication type:

Article

Molecular-targeted therapy for childhood low-grade glial and glioneuronal tumors.

Published in:

Child's Nervous System, 2024, v. 40, n. 10, p. 3251, doi. 10.1007/s00381-024-06486-6

By:

Siegel, Benjamin I.;
Duke, Elizabeth S.;
Kilburn, Lindsay B.;
Packer, Roger J.

Publication type:

Article

Treatment of tuberous sclerosis complex manifestations in children with mTOR inhibitors.

Published in:

Child's Nervous System, 2024, v. 40, n. 3, p. 831, doi. 10.1007/s00381-023-06218-2

By:

Yeşil, Şule;
Kurucu, Burçak;
Hamamcı, Melda Berber;
Yılmaz, Şükriye;
Şahin, Gürses

Publication type:

Article

An updated meta-analysis of effectiveness and safety of mTOR inhibitors in the management of tuberous sclerosis complex patients.

Published in:

Child's Nervous System, 2024, v. 40, n. 3, p. 823, doi. 10.1007/s00381-023-06200-y

By:

Liu, Mengling;
Ye, Jiayou;
You, Xiaoling

Publication type:

Article

Isolated subependymal giant cell astrocytoma (SEGA) in the absence of clinical tuberous sclerosis: two case reports and literature review.

Published in:

Child's Nervous System, 2024, v. 40, n. 1, p. 73, doi. 10.1007/s00381-023-06105-w

By:

Cobourn, Kelsey D.;
Chesney, Kelsi M.;
Mueller, Kyle;
Fayed, Islam;
Tsering, Deki;
Keating, Robert F.

Publication type:

Article

Kaposiform hemangioendothelioma of skull base with dura invasion in a pediatric patient: a case report.

Published in:

2023

By:

Jung, Seong-Chan;
Jung, Tae-Young;
Lee, Tae-Kyu;
Kim, Yeong Jin;
Baek, Hee Jo;
Kim, Sung Soon

Publication type:

Case Study

Current trends in the management of subependymal giant cell astrocytomas in tuberous sclerosis.

Published in:

Child's Nervous System, 2020, v. 36, n. 10, p. 2527, doi. 10.1007/s00381-020-04889-9

By:

Frassanito, Paolo;
Noya, Carolina;
Tamburrini, Gianpiero

Publication type:

Article

New treatment modalities in NF-related neuroglial tumors.

Published in:

Child's Nervous System, 2020, v. 36, n. 10, p. 2377, doi. 10.1007/s00381-020-04704-5

By:

Packer, Roger J.;
Vezina, Gilbert

Publication type:

Article

Neurosurgical treatment of subependymal giant cell astrocytomas in tuberous sclerosis complex: a series of 44 surgical procedures in 31 patients.

Published in:

Child's Nervous System, 2020, v. 36, n. 5, p. 951, doi. 10.1007/s00381-019-04449-w

By:

Giordano, Flavio;
Moscheo, Carla;
Lenge, Matteo;
Biagiotti, Roberto;
Mari, Francesco;
Sardi, Iacopo;
Buccoliero, Anna Maria;
Mongardi, Lorenzo;
Aronica, Eleonora;
Guerrini, Renzo;
Genitori, Lorenzo

Publication type:

Article

A natural diarylheptanoid protects cortical neurons against oxygen–glucose deprivation‐induced autophagy and apoptosis.

Published in:

Journal of Pharmacy & Pharmacology, 2019, v. 71, n. 7, p. 1110, doi. 10.1111/jphp.13096

By:

Shi, Qiaoyun;
Zhang, Qinghua;
Peng, Yinghui;
Zhang, Xiaoqi;
Wang, Ying;
Shi, Lei

Publication type:

Article

Xerosis as the toxicity of novel anti-cancer therapies — pathophysiology and management.

Published in:

Forum Dermatologicum, 2023, v. 9, n. 2, p. 50, doi. 10.5603/FD.a2023.0004

By:

Głuszak, Paweł;
Winkel, Katarzyna;
Dzieciątkowska, Marta;
Grzejda, Michał;
Ignasiak, Aleksandra;
Kurzyca, Julia;
Piotrowski, Igor

Publication type:

Article

Glycolytic inhibition: an effective strategy for developing calorie restriction mimetics.

Published in:

GeroScience, 2021, v. 43, n. 3, p. 1159, doi. 10.1007/s11357-020-00298-7

By:

Ingram, Donald K.;
Roth, George S.

Publication type:

Article

Effect of caloric restriction and rapamycin on ovarian aging in mice.

Published in:

GeroScience, 2019, v. 41, n. 4, p. 395, doi. 10.1007/s11357-019-00087-x

By:

Garcia, Driele N.;
Saccon, Tatiana D.;
Pradiee, Jorgea;
Rincón, Joao A. A.;
Andrade, Kelvin R. S.;
Rovani, Monique T.;
Mondadori, Rafael G.;
Cruz, Luis A. X.;
Barros, Carlos C.;
Masternak, Michal M.;
Bartke, Andrzej;
Mason, Jeffrey B.;
Schneider, Augusto

Publication type:

Article

mTORC1 inhibition may improve T lymphocytes affected by aging.

Published in:

Immunopharmacology & Immunotoxicology, 2023, v. 45, n. 6, p. 719, doi. 10.1080/08923973.2023.2232101

By:

Asghari, F.;
Karimi, M. H.;
Pourfathollah, A. A.

Publication type:

Article

Tuberous sclerosis: a review of the past, present, and future.

Published in:

Turkish Journal of Medical Sciences, 2020, v. 50, p. 1665, doi. 10.3906/sag-2002-133

By:

UYSAL, Sanem Pınar;
ŞAHİN, Mustafa

Publication type:

Article

IDENTIFICATION OF PHARMACOLOGICALLY RELEVANT MUTATIONS IN ENDOMETRIAL CANCER BY WHOLE-EXOME SEQUENCING OF FFPE TUMOUR SAMPLES.

Published in:

Farmacia, 2024, v. 72, n. 5, p. 1171, doi. 10.31925/farmacia.2024.5.20

By:

BOTEA, ROBERT;
PIRON-DUMITRASCU, MADALINA;
GEORGESCU, TIBERIU AUGUSTIN;
VOINEA, SILVIU CRISTIAN;
VARLAS, VALENTIN NICOLAE;
IACOBAN, SIMONA RALUCA;
SUCIU, NICOLAE

Publication type:

Article

PEComa with TFE3 mutations – from identification to treatment.

Published in:

Oncolog-Hematolog, 2023, n. 64, p. 48

By:

Ștefan, Oana;
Iacob, Simona

Publication type:

Article

Targeting one-carbon metabolism requires mTOR inhibition: a new therapeutic approach in osteosarcoma.

Published in:

Molecular & Cellular Oncology, 2021, v. 8, n. 3, p. 1, doi. 10.1080/23723556.2021.1902250

By:

Rathore, Richa;
Van Tine, Brian

Publication type:

Article

Targeting ganglioneuromas with mTOR inhibitors.

Published in:

Molecular & Cellular Oncology, 2021, v. 8, n. 1, p. 1, doi. 10.1080/23723556.2020.1856621

By:

Tao, Ting;
Shi, Hui;
Durbin, Adam D.;
Look, A. Thomas

Publication type:

Article

Phosphatidic acid: a lipid regulator of the Hippo pathway.

Published in:

Molecular & Cellular Oncology, 2019, v. 6, n. 1, p. 1, doi. 10.1080/23723556.2018.1558683

By:

Han, Han;
Vargas, Rebecca;
Seo, Gayoung;
Wang, Wenqi

Publication type:

Article

Hematological toxicity of mTOR inhibitors is mild and dose-dependent in patients with tuberous sclerosis and subependymal giant cell astrocytoma.

Published in:

Acta Haematologica Polonica, 2023, v. 54, n. 4, p. 227, doi. 10.5603/AHP.a2023.0035

By:

Urbański, Bartosz;
Pawlik, Bartłomiej;
Młynarski, Wojciech;
Trelińska, Joanna

Publication type:

Article

ONC201/TIC10 enhances durability of mTOR inhibitor everolimus in metastatic ER+ breast cancer.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.85898

By:

Farmaki, Elena;
Nath, Aritro;
Emond, Rena;
Karimi, Kimya L.;
Grolmusz, Vince K.;
Cosgrove, Patrick A.;
Bild, Andrea H.

Publication type:

Article

The case for the therapeutic use of mechanistic/mammalian target of rapamycin (mTOR) inhibitors in xenotransplantation.

Published in:

Xenotransplantation, 2023, v. 30, n. 3, p. 1, doi. 10.1111/xen.12802

By:

Maenaka, Akihiro;
Kinoshita, Kohei;
Hara, Hidetaka;
Cooper, David K. C.

Publication type:

Article

TNF stimulates IL‐6, CXCL8 and VEGF secretion from human keratinocytes via activation of mTOR, inhibited by tetramethoxyluteolin.

Published in:

Experimental Dermatology, 2018, v. 27, n. 2, p. 135, doi. 10.1111/exd.13461

By:

Patel, Arti B.;
Tsilioni, Irene;
Weng, Zuyi;
Theoharides, Theoharis C.

Publication type:

Article

Clinical research progress of ridaforolimus (AP23573, MK8668) over the past decade: a systemic review.

Published in:

Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1173240

By:

Lumin Wang;
Qining Qiu;
Dawei Yang;
Chang Cao;
Yanqin Lu;
Yulan Zeng;
Weiwen Jiang;
Yun Shen;
Yanrong Ye

Publication type:

Article

Mammalian Target of Rapamycin (mTOR) and the Proteasome Attenuates IL-1β Expression in Primary Mouse Cardiac Fibroblasts.

Published in:

Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2019.01285

By:

Torp, May-Kristin;
Yang, Kuan;
Ranheim, Trine;
Husø Lauritzen, Knut;
Alfsnes, Katrine;
Vinge, Leif E.;
Aukrust, Pål;
Stensløkken, Kåre-Olav;
Yndestad, Arne;
Sandanger, Øystein

Publication type:

Article

Immunomodulatory Effects of Flavonoids: Possible Induction of T CD4+ Regulatory Cells Through Suppression of mTOR Pathway Signaling Activity.

Published in:

Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2019.00051

By:

Hosseinzade, Aysooda;
Sadeghi, Omid;
Naghdipour Biregani, Akram;
Soukhtehzari, Sepideh;
Brandt, Gabriel S.;
Esmaillzadeh, Ahmad

Publication type:

Article

Regulation of Dendritic Cell Immune Function and Metabolism by Cellular Nutrient Sensor Mammalian Target of Rapamycin (mTOR).

Published in:

Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2018.03145

By:

Snyder, Julia P.;
Amiel, Eyal

Publication type:

Article

Helicobacter pylori CagA Protein Negatively Regulates Autophagy and Promotes Inflammatory Response via c-Met-PI3K/Akt-mTOR Signaling Pathway.

Published in:

Frontiers in Cellular & Infection Microbiology, 2017, p. 1, doi. 10.3389/fcimb.2017.00417

By:

Na Li;
Bin Tang;
Yin-ping Jia;
Pan Zhu;
Yuan Zhuang;
Yao Fang;
Qian Li;
Kun Wang;
Wei-jun Zhang;
Gang Guo;
Tong-jian Wang;
You-jun Feng;
Bin Qiao;
Xu-hu Mao;
Quan-ming Zou

Publication type:

Article

Postrenal transplant malignancy: An update for clinicians.

Published in:

Indian Journal of Transplantation, 2023, v. 17, n. 4, p. 389, doi. 10.4103/ijot.ijot_60_23

By:

Soni, Renuka;
Ranjan, Priyadarshi

Publication type:

Article

Surgical Site Infections in Solid Organ Transplant Recipients: Expert Group Opinion for Prophylaxis and Management in South Asia.

Published in:

Indian Journal of Transplantation, 2022, v. 16, p. S89, doi. 10.4103/ijot.ijot_98_21

By:

Seth, Abhinav;
Sharma, Ashish;
Gadde, Ashwinin B.;
Mandwar, Milind;
Bansal, Shyam Bihari

Publication type:

Article

Rapamycin attenuates reconsolidation of a backwards-conditioned aversive stimuli in female mice.

Published in:

Psychopharmacology, 2024, v. 241, n. 3, p. 601, doi. 10.1007/s00213-024-06544-6

By:

Trask, Jared;
MacCallum, Phillip E.;
Rideout, Haley;
Preisser, Evan L.;
Blundell, Jacqueline J.

Publication type:

Article

Electroconvulsive seizure inhibits the mTOR signaling pathway via AMPK in the rat frontal cortex.

Published in:

Psychopharmacology, 2022, v. 239, n. 2, p. 443, doi. 10.1007/s00213-021-06015-2

By:

Kim, Se Hyun;
Yu, Hyun Sook;
Huh, Seonghoo;
Kang, Ung Gu;
Kim, Yong Sik

Publication type:

Article

Structure-based design and biological evaluation of novel mTOR inhibitors as potential anti-cervical agents.

Published in:

Journal of Chinese Pharmaceutical Sciences, 2020, v. 29, n. 9, p. 603, doi. 10.5246/jcps.2020.09.056

By:

Peili Jiao;
Yiyan Li;
Xing Wu;
Yuxi Wang;
Beibei Mao;
Hongwei Jin;
Lihe Zhang;
Liangren Zhang;
Zhenming Liu

Publication type:

Article

Pyomyositis in a Patient with IgA Nephropathy and Kidney Transplant.

Published in:

Case Reports in Transplantation, 2019, p. 1, doi. 10.1155/2019/7305683

By:

Xipell, M.;
Ventura-Aguiar, P.;
Revuelta, I.;
Bodro, M.;
Diekmann, F.

Publication type:

Article

Dual Diagnosis of Fragile X Syndrome and DEPDC5‐Related Disorder Emphasizes DEPDC5's Role Beyond Familial Epilepsy: A Case Report and Literature Review.

Published in:

2025

By:

Edwards, Rory;
Murphy, Grace;
Owens, Joshua W.;
Erickson, Craig;
Hopkin, Robert;
Shillington, Amelle;
Das, Sofia Priyadarsani

Publication type:

Case Study

The PI3K/mTOR dual inhibitor GSK458 potently impedes ovarian cancer tumorigenesis and metastasis.

Published in:

Cellular Oncology (2211-3428), 2020, v. 43, n. 4, p. 669, doi. 10.1007/s13402-020-00514-8

By:

Xiao, Yangjiong;
Yu, Yang;
Jiang, Pengcheng;
Li, Yuhong;
Wang, Chao;
Zhang, Rong

Publication type:

Article

mTOR inhibitor INK128 promotes wound healing by regulating MDSCs.

Published in:

Stem Cell Research & Therapy, 2021, v. 12, n. 1, p. 1, doi. 10.1186/s13287-021-02206-y

By:

Li, Yi;
Xu, Yujun;
Liu, Xinhan;
Yan, Xin;
Lin, Yue;
Tan, Qian;
Hou, Yayi

Publication type:

Article

Two most common diagnoses among myriads of cystic lung diseases.

Published in:

Hippokratia, 2021, v. 25, n. 2, p. 83

By:

Swol, J.;
Würflein, D.;
Böhm, J.;
Ficker, J. H.

Publication type:

Article

Recent Advances and Challenges in the Treatment of Advanced Pancreatic Cancer: An Update on Completed and Ongoing Clinical Trials.

Published in:

Cancers, 2025, v. 17, n. 8, p. 1319, doi. 10.3390/cancers17081319

By:

Shenoy, Abhinav;
Yousif, Amar;
Hussain, Muhammad Delwar

Publication type:

Article

Antibody-Based and Other Novel Agents in Adult B-Cell Acute Lymphoblastic Leukemia.

Published in:

Cancers, 2025, v. 17, n. 5, p. 779, doi. 10.3390/cancers17050779

By:

Csizmar, Clifford M.;
Litzow, Mark R.;
Saliba, Antoine N.

Publication type:

Article

Morpholine-Substituted Tetrahydroquinoline Derivatives as Potential mTOR Inhibitors: Synthesis, Computational Insights, and Cellular Analysis.

Published in:

Cancers, 2025, v. 17, n. 5, p. 759, doi. 10.3390/cancers17050759

By:

Dey, Rajdeep;
Shaw, Suman;
Yadav, Ruchi;
Patel, Bhumika D.;
Bhatt, Hardik G.;
Natesan, Gopal;
Jha, Abhishek B.;
Chaube, Udit

Publication type:

Article

What We Know and Do Not Yet Know About the Canine Model of Lymphoma in Human Medicine—The Current State of Knowledge.

Published in:

Cancers, 2025, v. 17, n. 4, p. 596, doi. 10.3390/cancers17040596

By:

Będkowska, Daria;
Al-Ameri, Sara;
Wieczorek, Agnieszka;
Bubak, Joanna;
Miszczak, Marta

Publication type:

Article

The Prospects of Curcumin in Non-Small Cell Lung Cancer Therapeutics.

Published in:

2025

By:

Papavassiliou, Kostas A.;
Sofianidi, Amalia A.;
Gogou, Vassiliki A.;
Papavassiliou, Athanasios G.

Publication type:

Editorial