Works matching DE "MITOFUSIN 2"

Results: 213

RIPK4-mediated MFN2 degradation drives osteogenesis through mitochondrial fragmentation and restricts myelopoiesis by blocking mitochondrial transfer.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-61808-9

By:

Ding, Peng;
Wang, Xing;
Gao, Chuan;
Wei, Yuehan;
Li, Gan;
Zhu, Wenlei;
Wang, Ni;
Fu, Wan;
Fang, Qihang;
Yao, Meng;
Huang, Yigang;
Jiang, Chenyi;
Gao, Youshui;
Zhang, Jing;
Gao, Junjie;
Zhong, Qing;
Zhang, Changqing

Publication type:

Article

Tang Bi formula alleviates diabetic sciatic neuropathy via AMPK/PGC-1α/MFN2 pathway activation.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-10513-0

By:

Yang, Cunqing;
Yu, Honghai;
Zhou, Linfeng;
Su, Hang;
Li, Xiangyan;
Qi, Wenxiu;
Lian, Fengmei

Publication type:

Article

Mitochondrial Fragmentation and Long Noncoding RNA MALAT1 in Diabetic Retinopathy.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6429, doi. 10.3390/ijms26136429

By:

Kowluru, Renu A.;
Kumar, Jay

Publication type:

Article

Isoliquiritigenin pretreatment regulates ER stress and attenuates cisplatin‐induced nephrotoxicity in male Wistar rats.

Published in:

Journal of Biochemical & Molecular Toxicology, 2023, v. 37, n. 12, p. 1, doi. 10.1002/jbt.23492

By:

Gómez‐Sierra, Tania;
Ortega‐Lozano, Ariadna J.;
Rojas‐Morales, Pedro;
Medina‐Reyes, Estefany I.;
Barrera‐Oviedo, Diana;
Pedraza‐Chaverri, José

Publication type:

Article

Knockdown of circMFN2 inhibits cell progression and glycolysis by miR‐198/CUL4B pathway in ovarian cancer.

Published in:

Journal of Biochemical & Molecular Toxicology, 2023, v. 37, n. 8, p. 1, doi. 10.1002/jbt.23383

By:

Song, Rui;
Chai, Ting;
Liu, Junqi;
Chu, Alan;
Sun, Chen;
Liu, Zongwen

Publication type:

Article

Homocysteine induced a calcium‐mediated disruption of mitochondrial function and dynamics in endothelial cells.

Published in:

Journal of Biochemical & Molecular Toxicology, 2021, v. 35, n. 5, p. 1, doi. 10.1002/jbt.22737

By:

Chen, Li‐ting;
Xu, Ting‐ting;
Qiu, Ya‐qing;
Liu, Nuo‐ya;
Ke, Xin‐yu;
Fang, Lu;
Yan, Jie‐ping;
Zhu, Dan‐yan

Publication type:

Article

Krüppel like factor 7 regulates mitochondrial dynamics balance in myocardial infarction.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-08139-z

By:

Wang, Cao;
Zhu, Fuxing;
Zhou, Lan;
Zhang, Situo;
Wang, Ruiqi;
Tian, Hui;
Zhang, Bosong;
Wu, Jiahui;
Xu, Xiang;
Jiang, Ruixian;
Hou, Xiaolu;
Liu, Jian;
Tian, Weiming

Publication type:

Article

Dietary Sodium Nitrate Activates Antioxidant and Mitochondrial Dynamics Genes after Moderate Intensity Acute Exercise in Metabolic Syndrome Patients.

Published in:

Journal of Clinical Medicine, 2021, v. 10, n. 12, p. 2618, doi. 10.3390/jcm10122618

By:

Ferrer, Miguel D.;
Capó, Xavier;
Reynés, Clara;
Quetglas, Magdalena;
Salaberry, Eduardo;
Tonolo, Federica;
Suau, Rafael;
Marí, Bartolomé;
Tur, Josep A.;
Sureda, Antoni;
Pons, Antoni

Publication type:

Article

Back to The Fusion: Mitofusin-2 in Alzheimer's Disease.

Published in:

Journal of Clinical Medicine, 2020, v. 9, n. 1, p. 126, doi. 10.3390/jcm9010126

By:

Sita, Giulia;
Hrelia, Patrizia;
Graziosi, Agnese;
Morroni, Fabiana

Publication type:

Article

Profiling circRNA and lncRNA Expression in Key Bovine Metabolic Tissues.

Published in:

2021

By:

Jian Wang;
Hui-Zeng Sun;
O'Hara, Eóin;
Hong Chen;
Leluo Guan

Publication type:

Abstract

Silybin Alleviated Hepatic Injury by Regulating Redox Balance, Inflammatory Response, and Mitochondrial Function in Weaned Piglets under Paraquat-Induced Oxidative Stress.

Published in:

Antioxidants, 2024, v. 13, n. 3, p. 324, doi. 10.3390/antiox13030324

By:

Cai, Long;
Ming, Dongxu;
Chen, Wenning;
Zhao, Ying;
Li, Yanpin;
Sun, Wenjuan;
Pi, Yu;
Jiang, Xianren;
Li, Xilong

Publication type:

Article

Mulberry Leaf Polysaccharides Attenuate Oxidative Stress Injury in Peripheral Blood Leukocytes by Regulating Endoplasmic Reticulum Stress.

Published in:

Antioxidants, 2024, v. 13, n. 2, p. 136, doi. 10.3390/antiox13020136

By:

Jiang, Wenqiang;
Lin, Yan;
Qian, Linjie;
Lu, Siyue;
Shen, Huaishun;
Ge, Xianping;
Miao, Linghong

Publication type:

Article

Pectolinarigenin Improves Oxidative Stress and Apoptosis in Mouse NSC-34 Motor Neuron Cell Lines Induced by C9-ALS-Associated Proline–Arginine Dipeptide Repeat Proteins by Enhancing Mitochondrial Fusion Mediated via the SIRT3/OPA1 Axis.

Published in:

Antioxidants, 2023, v. 12, n. 11, p. 2008, doi. 10.3390/antiox12112008

By:

Fu, Ru-Huei

Publication type:

Article

A human mitofusin 2 mutation can cause mitophagic cardiomyopathy.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.84235

By:

Franco, Antonietta;
Jiajia Li;
Kelly, Daniel P.;
Hershberger, Ray E.;
Marian, Ali J.;
Lewis, Renate M.;
Moshi Song;
Xiawei Dang;
Schmidt, Alina D.;
Mathyer, Mary E.;
Edwards, John R.;
de Guzman Strong, Cristina;
Dorn, Gerald W.

Publication type:

Article

Atypical peripheral actin band formation via overactivation of RhoA and nonmuscle myosin II in mitofusin 2-deficient cells.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.88828

By:

Yueyang Wang;
Troughton, Lee D.;
Fan Xu;
Chatterjee, Aritra;
Chang Ding;
Han Zhao;
Cifuentes, Laura p.;
Wagner, Ryan B.;
Tianqi Wang;
Shelly Tan;
Jingjuan Chen;
Linlin Li;
Umulis, David;
Shihuan Kuang;
Suter, Daniel M.;
Chongli Yuan;
Chan, Deva;
Fang Huang;
Oakes, Patrick W.;
Qing Deng

Publication type:

Article

Norepinephrine Attenuates Benzalkonium Chloride-Induced Dry Eye Disease by Regulating the PINK1/Parkin Mitophagy Pathway.

Published in:

Ocular Immunology & Inflammation, 2025, v. 33, n. 5, p. 766, doi. 10.1080/09273948.2024.2447816

By:

Zhao, Han;
Wang, Wushuang;
Yang, Yun;
Feng, Changming;
Lin, Tong;
Gong, Lan

Publication type:

Article

Mitochondrial fusion protein: a new therapeutic target for lung injury diseases.

Published in:

Frontiers in Physiology, 2025, p. 1, doi. 10.3389/fphys.2025.1500247

By:

Jia, Guiyang;
Song, Erqin;
Huang, Qianxia;
Chen, Miao;
Liu, Guoyue

Publication type:

Article

Mechanical regulation of metabolic reprogramming of vascular smooth muscle cells in vein grafts.

Published in:

2022

By:

Yuanjun Tang;
Wei Pang;
Jing Zhou

Publication type:

Abstract

Irisin improves ROS‑induced mitohormesis imbalance in H9c2 cells.

Published in:

Molecular Medicine Reports, 2024, v. 30, n. 6, p. N.PAG, doi. 10.3892/mmr.2024.13364

By:

Wang, Baogui;
Xu, Haibo;
Shang, Shuai;
Liu, Longxiang;
Sun, Chunlong;
Du, Wen

Publication type:

Article

Mammalian STE20-like kinase 1 regulates pancreatic cancer cell survival and migration through Mfn2-mediated mitophagy.

Published in:

Molecular Medicine Reports, 2020, v. 22, n. 1, p. 398, doi. 10.3892/mmr.2020.11098

By:

Hu, Yongli;
Wang, Bing;
Wang, Lie;
Wang, Zhenran;
Jian, Zhiyuan;
Deng, Lin

Publication type:

Article

Spectrum and frequencies of mutations in the MFN2 gene and its phenotypical expression in Czech hereditary motor and sensory neuropathy type II patients.

Published in:

Molecular Medicine Reports, 2013, v. 8, n. 6, p. 1779, doi. 10.3892/mmr.2013.1730

By:

BROŽKOVÁ, DANA ŠAFKA;
POSÁDKA, JAN;
LAŠŠUTHOVÁ, PETRA;
MAZANEC, RADIM;
HABERLOVÁ, JANA;
ŠIŠKOVÁ, DANA;
SAKMARYOVÁ, IVA;
NEUPAUEROVÁ, JANA;
SEEMAN, PAVEL

Publication type:

Article

Is there an association between pelvic organ prolapse and oxidative stress? A systematic review.

Published in:

PLoS ONE, 2022, v. 17, n. 8, p. 1, doi. 10.1371/journal.pone.0271467

By:

Habes, Dominik;
Kestranek, Jan;
Stranik, Jaroslav;
Kacerovsky, Marian;
Spacek, Jiri

Publication type:

Article

Aging promotes an increase in mitochondrial fragmentation in astrocytes.

Published in:

Frontiers in Cellular Neuroscience, 2024, p. 1, doi. 10.3389/fncel.2024.1496163

By:

Araujo, Ana Paula Bergamo;
Vargas, Gabriele;
Hayashide, Lívia de Sá;
Matias, Isadora;
Andrade, Cherley Borba Vieira;
de Carvalho, Jorge José;
Gomes, Flávia Carvalho Alcantara;
Diniz, Luan Pereira

Publication type:

Article

Effects of Recombinant Human Erythropoietin on Inflammatory Factors in Rats with Traumatic Brain Injury.

Published in:

Indian Journal of Pharmaceutical Sciences, 2021, v. 83, n. 3, p. 541, doi. 10.36468/pharmaceutical-sciences.803

By:

KAI XUE;
ZHENG JIN;
BINBIN ZHANG;
GUOQING HAN;
CHEN ZHANG

Publication type:

Article

Acquired Expression of Mutant Mitofusin 2 Causes Progressive Neurodegeneration and Abnormal Behavior.

Published in:

Journal of Neuroscience, 2019, v. 39, n. 9, p. 1588, doi. 10.1523/JNEUROSCI.2139-18.2018

By:

Takayuki Mito;
Kaori Ishikawa;
Kazuto Nakada;
Haruna Tani;
Satoshi Yamamoto;
Naoya Nishimura;
Hirokazu Matsumoto;
Satoko Hattori;
Tsuyoshi Miyakawa

Publication type:

Article

Intracellular Chloride Channels Regulate Endothelial Metabolic Reprogramming in Pulmonary Arterial Hypertension.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2023, v. 68, n. 1, p. 103, doi. 10.1165/rcmb.2022-0111OC

By:

Alzaydi, Mai M.;
Abdul-Salam, Vahitha B.;
Whitwell, Harry J.;
Russomanno, Giusy;
Glynos, Angelos;
Capece, Daria;
Szabadkai, Gyorgy;
Wilkins, Martin R.;
Wojciak-Stothard, Beata

Publication type:

Article

Type 2 diabetic patients and their offspring show altered parameters of iron status, oxidative stress and genes related to mitochondrial activity.

Published in:

BioMetals, 2012, v. 25, n. 4, p. 725, doi. 10.1007/s10534-012-9540-z

By:

Blanc, Solange;
Villarroel, Pia;
Candia, Valeria;
Gavilán, Natalia;
Soto, Néstor;
Pérez-Bravo, Francisco;
Arredondo, Miguel

Publication type:

Article

Mitochondrial Dynamics in Tachycardiomyopathy.

Published in:

Cellular Physiology & Biochemistry (Cell Physiol Biochem Press GmbH & Co. KG), 2019, v. 52, n. 4, p. 435, doi. 10.33594/000000031

By:

Heinzmann, David;
Klingel, Karin;
Müller, Karin;
Kumbrink, Jörg;
Kirchner, Thomas;
Schreieck, Jürgen;
Gawaz, Meinrad;
Seizer, Peter

Publication type:

Article

Mitofusin-2 boosts innate immunity through the maintenance of aerobic glycolysis and activation of xenophagy in mice.

Published in:

Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-02073-6

By:

Silwal, Prashanta;
Kim, Jin Kyung;
Jeon, Sang Min;
Lee, June-Young;
Kim, Young Jae;
Kim, Yi Sak;
Seo, Yeji;
Kim, Jihye;
Kim, Soo Yeon;
Lee, Min Joung;
Heo, Jun Young;
Jung, Mi-Ja;
Kim, Hyun Sik;
Hyun, Dong-Wook;
Han, Jeong Eun;
Whang, Jake;
Huh, Yang Hoon;
Lee, Sang-Hee;
Heo, Won Do;
Kim, Jin-Man

Publication type:

Article

Peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) overexpression alleviates endoplasmic reticulum stress after acute kidney injury.

Published in:

Renal Failure, 2022, v. 44, n. 1, p. 358, doi. 10.1080/0886022X.2022.2035764

By:

Pan, Hao;
Hu, Zhizhi;
Shao, Zhongwen;
Ning, Yong

Publication type:

Article

IRF1-mediated upregulation of PARP12 promotes cartilage degradation by inhibiting PINK1/Parkin dependent mitophagy through ISG15 attenuating ubiquitylation and SUMOylation of MFN1/2.

Published in:

Bone Research, 2024, v. 12, n. 1, p. 1, doi. 10.1038/s41413-024-00363-3

By:

Deng, Zengfa;
Long, Dianbo;
Li, Changzhao;
Liu, Hailong;
Li, Wei;
Zhong, Yanlin;
Mo, Xiaolin;
Li, Ruiyun;
Yang, Zibo;
Kang, Yan;
Mao, Guping

Publication type:

Article

Loss and recovery of myocardial mitochondria in mice under different tail suspension time: Apoptosis and mitochondrial fission, fusion and autophagy.

Published in:

Experimental Physiology, 2023, v. 108, n. 9, p. 1189, doi. 10.1113/EP090518

By:

Wang, Zhe;
Wang, Xing‐Chen;
Chen, Ya‐Fei;
Wang, Chuan‐Li;
Chen, Le;
Jiang, Ming‐Yue;
Liu, Xi‐Wei;
Zhang, Xiao‐Xuan;
Feng, Yong‐Zhen;
Xu, Jin‐Hui

Publication type:

Article

MFN2 ameliorates cell apoptosis in a cellular model of Parkinson's disease induced by rotenone.

Published in:

Experimental & Therapeutic Medicine, 2018, v. 16, n. 4, p. 3680, doi. 10.3892/etm.2018.6595

By:

Yang, Yang;
Xue, Liu-Jun;
Xue, Xiao;
Ou, Zhou;
Jiang, Teng;
Zhang, Ying-Dong

Publication type:

Article

Activation of protein kinase C-α/heme oxygenase-1 signaling pathway improves mitochondrial dynamics in lipopolysaccharide-activated NR8383 cells.

Published in:

Experimental & Therapeutic Medicine, 2018, v. 16, n. 2, p. 1529, doi. 10.3892/etm.2018.6290

By:

Li, Xiangyun;
Zhang, Yuan;
Yu, Jianbo;
Mu, Rui;
Wu, Lili;
Shi, Jia;
Gong, Lirong;
Liu, Daquan

Publication type:

Article

Role of mitofusin 2 in the protective effect of breviscapine against hepatic ischemia/reperfusion injury in rats.

Published in:

Experimental & Therapeutic Medicine, 2018, v. 15, n. 4, p. 3582, doi. 10.3892/etm.2018.5834

By:

Bao, Zhen;
Chen, Weijun;
Pan, Fan;
Peng, Bo;
Gong, Jin

Publication type:

Article

MicroRNA-31 promotes arterial smooth muscle cell proliferation and migration by targeting mitofusin-2 in arteriosclerosis obliterans of the lower extremitie.

Published in:

Experimental & Therapeutic Medicine, 2018, v. 15, n. 1, p. 633, doi. 10.3892/etm.2017.5453

By:

Huang, Shuichuan;
Chen, Zhibo;
Wu, Weibin;
Wang, Mian;
Wang, Rui;
Cui, Jin;
Li, Wen;
Wang, Shenming

Publication type:

Article

Lentivirus vector-mediated mitofusin-2 overexpression in rat ovary changes endocrine function and promotes follicular development in vivo.

Published in:

Experimental & Therapeutic Medicine, 2014, v. 8, n. 3, p. 731, doi. 10.3892/etm.2014.1835

By:

XIAOJING HU;
XIUBING LEI;
JIDONG WANG;
HONGJUAN PAN;
CONG LI;
ZHENWEI YAO

Publication type:

Article

Effect of galangin on oxidative stress, antioxidant defenses and mitochondrial dynamics in a rat model of focal cerebral ischemia.

Published in:

Biomedical Reports, 2025, v. 22, n. 1, p. N.PAG, doi. 10.3892/br.2024.1888

By:

Supawat, Araya;
Palachai, Nut;
Jittiwat, Jinatta

Publication type:

Article

Late‐onset hereditary sensory and autonomic neuropathy expands the phenotypic spectrum of MFN2‐related diseases.

Published in:

2018

By:

Wu, Rui;
Fu, Jun;
Meng, Lingchao;
Lv, He;
Wang, Zhaoxia;
Yuan, Yun

Publication type:

Case Study

CRMP2 Participates in Regulating Mitochondrial Morphology and Motility in Alzheimer's Disease.

Published in:

Cells (2073-4409), 2023, v. 12, n. 9, p. 1287, doi. 10.3390/cells12091287

By:

Brustovetsky, Tatiana;
Khanna, Rajesh;
Brustovetsky, Nickolay

Publication type:

Article

Mitochondria-Endoplasmic Reticulum Interplay Regulates Exo-Cytosis in Human Neuroblastoma Cells.

Published in:

Cells (2073-4409), 2022, v. 11, n. 3, p. 514, doi. 10.3390/cells11030514

By:

Dentoni, Giacomo;
Naia, Luana;
Ankarcrona, Maria

Publication type:

Article

Loosening ER–Mitochondria Coupling by the Expression of the Presenilin 2 Loop Domain.

Published in:

Cells (2073-4409), 2021, v. 10, n. 8, p. 1968, doi. 10.3390/cells10081968

By:

Rossini, Michela;
García-Casas, Paloma;
Filadi, Riccardo;
Pizzo, Paola

Publication type:

Article

Amyloid β-Peptide Increases Mitochondria-Endoplasmic Reticulum Contact Altering Mitochondrial Function and Autophagosome Formation in Alzheimer's Disease-Related Models.

Published in:

Cells (2073-4409), 2020, v. 9, n. 12, p. 2552, doi. 10.3390/cells9122552

By:

Leal, Nuno Santos;
Dentoni, Giacomo;
Schreiner, Bernadette;
Naia, Luana;
Piras, Antonio;
Graff, Caroline;
Cattaneo, Antonio;
Meli, Giovanni;
Hamasaki, Maho;
Nilsson, Per;
Ankarcrona, Maria

Publication type:

Article

ANT2-Mediated ATP Import into Mitochondria Protects against Hypoxia Lethal Injury.

Published in:

Cells (2073-4409), 2020, v. 9, n. 12, p. 2542, doi. 10.3390/cells9122542

By:

Gouriou, Yves;
Alam, Muhammad Rizwan;
Harhous, Zeina;
Crola Da Silva, Claire;
Baetz, Delphine Baetz;
Badawi, Sally;
Lefai, Etienne;
Rieusset, Jennifer;
Durand, Annie;
Harisseh, Rania;
Gharib, Abdallah;
Ovize, Michel;
Bidaux, Gabriel

Publication type:

Article

Pro-apoptotic and anti-proliferative effects of mitofusin-2 via Bax signaling in hepatocellular carcinoma cells.

Published in:

Medical Oncology, 2012, v. 29, n. 1, p. 70, doi. 10.1007/s12032-010-9779-6

By:

Wang, Weilin;
Lu, Jianju;
Zhu, Feng;
Wei, Jianfeng;
Jia, Changku;
Zhang, Yuanbiao;
Zhou, Lin;
Xie, Haiyang;
Zheng, Shusen

Publication type:

Article

The oncogenic potential of Rab-like protein 1A (RBEL1A) GTPase: The first review of RBEL1A research with future research directions and challenges.

Published in:

Journal of Cancer, 2023, v. 14, n. 17, p. 3214, doi. 10.7150/jca.84267

By:

Ki Lui;
Ying Huang;
Saeed Sheikh, M.;
Kwok-Kuen Cheung;
Wing Yip Tam;
Keng-Ting Sun;
Ka Ming Cheng;
Wing Man Ng, Winnie;
Wai-Keung Loh, Anthony

Publication type:

Article

Mitofusin 1 and 2 regulation of mitochondrial DNA content is a critical determinant of glucose homeostasis.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-29945-7

By:

Sidarala, Vaibhav;
Zhu, Jie;
Levi-D'Ancona, Elena;
Pearson, Gemma L.;
Reck, Emma C.;
Walker, Emily M.;
Kaufman, Brett A.;
Soleimanpour, Scott A.

Publication type:

Article

Matrine Protects Cardiomyocytes Against Hyperglycemic Stress by Promoting Mitofusin 2-Induced Mitochondrial Fusion.

Published in:

Frontiers in Physiology, 2022, v. 11, p. 1, doi. 10.3389/fphys.2020.597429

By:

Tong Xiao;
Jie Huang;
Yuan Liu;
Yujie Zhao;
Manman Wei

Publication type:

Article

Impaired mitochondrial dynamics and removal of the damaged mitochondria in diabetic retinopathy.

Published in:

Frontiers in Endocrinology, 2023, p. 1, doi. 10.3389/fendo.2023.1160155

By:

Alka, Kumari;
Kumar, Jay;
Kowluru, Renu A.

Publication type:

Article

Exercise intervention improves mitochondrial quality in non-alcoholic fatty liver disease zebrafish.

Published in:

Frontiers in Endocrinology, 2023, p. 1, doi. 10.3389/fendo.2023.1162485

By:

Yun-Yi Zou;
Xiang-bin Tang;
Zhang-Lin Chen;
Bin Liu;
Lan Zheng;
Ming-Yang Song;
Qin Xiao;
Zuo-Qiong Zhou;
Xi-Yang Peng;
Chang-Fa Tang

Publication type:

Article