Works matching DE "MITOCHONDRIAL pathology"

Results: 5000

Transcriptomic skin niches in systemic sclerosis underpin a role for mitochondrial dysfunction Open Access.

Published in:

British Journal of Dermatology, 2025, v. 193, n. 2, p. 326, doi. 10.1093/bjd/ljaf119

By:

Wang, Junqin;
Hennessey, Dylan;
Iyer, Aishwarya;
O'Keefe, Sandra;
Khan, Lamia;
Redmond, Desiree;
Osman, Mohammed;
Gniadecki, Robert

Publication type:

Article

A non-invasive method for screening mitochondrial diabetes.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1536331

By:

Fang, Hangyu;
Li, Xiaoe;
Wang, Shuping;
Zhang, Mei;
Zhang, Victor Wei;
Xu, Chao

Publication type:

Article

Cardiomyocyte OTUD1 drives diabetic cardiomyopathy via directly deubiquitinating AMPKα2 and inducing mitochondrial dysfunction.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-61901-z

By:

Han, Xue;
Zheng, Ruyi;
Zhang, Jiajia;
Liu, Yanan;
Li, Ze;
Liu, Guoxuan;
Zheng, Jianing;
Li, Weiqi;
Liang, Zijun;
Wang, Mengyang;
Yu, Jie;
Shi, Qiaojuan;
Ying, Huazhong;
Liang, Guang

Publication type:

Article

The DRP1 receptor FIS1 is critical to the expansion of triple-negative breast cancer tumor-initiating cells.

Published in:

Cancer Cell International, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12935-025-03909-5

By:

Katrii, Tetiana;
Freywald, Tanya;
Estrada, Malkon G.;
El Zawily, Amr;
Toosi, Behzad;
Vizeacoumar, Frederick S.;
Vizeacoumar, Franco J.;
Freywald, Andrew;
Leary, Scot C.

Publication type:

Article

The SARS-CoV-2 main protease causes mitochondrial dysfunction in a yeast model.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-11993-w

By:

Grabiński, Wojciech;
Kicińska, Anna;
Funtowicz, Karolina;
Skrzypczak, Tomasz;
Karachitos, Andonis

Publication type:

Article

Inhibiting CD36 palmitoylation improves cardiac function post-infarction by regulating lipid metabolic homeostasis and autophagy.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-61875-y

By:

Zhang, Qingwei;
Li, Jiamin;
Liu, Xin;
Chen, Ximing;
Zhu, Liwei;
Zhang, Zhen;
Hu, Yingying;
Zhao, Tong;
Lou, Han;
Xu, Henghui;
Zhao, Wenjie;
Dong, Xinxin;
Sun, Zeqi;
Sun, Xiuxiu;
Yang, Baofeng;
Zhang, Yong

Publication type:

Article

Identification of Serum Biomarkers for Blast-induced Traumatic Brain Injuries: Low vs. High-intensity Exposure in a Rat Model.

Published in:

In Vivo, 2025, v. 39, n. 4, p. 1840, doi. 10.21873/invivo.13984

By:

BERA, ALAKESH;
SUBHRAMANIAN, MADHAN;
SHARMA, PUSHPA

Publication type:

Article

Editorial: Mitochondrial damage interacts with the immune system and tumor microenvironment.

Published in:

2025

By:

Lin, Xundong;
Yuan, Xin;
Luo, Yiheng;
Fang, Haihong;
Guo, Weihong

Publication type:

Editorial

Mitochondrial unfolded protein response in regulatory T cell function: a protective mechanism in immune aging.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1621759

By:

Lewis, Lillie;
Valvi, Deepa;
Gedaly, Roberto;
Marti, Francesc

Publication type:

Article

Mitochondria-derived peptide MOTS-c restores mitochondrial respiration in type 2 diabetic heart.

Published in:

Frontiers in Physiology, 2025, p. 1, doi. 10.3389/fphys.2025.1602271

By:

Pham, Toan;
Taberner, Andrew;
Hickey, Anthony;
Han, June-Chiew

Publication type:

Article

Nutraceutical Strategies for Targeting Mitochondrial Dysfunction in Neurodegenerative Diseases.

Published in:

Foods, 2025, v. 14, n. 13, p. 2193, doi. 10.3390/foods14132193

By:

Davì, Federica;
Iaconis, Antonella;
Cordaro, Marika;
Di Paola, Rosanna;
Fusco, Roberta

Publication type:

Article

Mitochondrial Quality Control in Bovine Oocyte Maturation: Mechanisms, Challenges, and Prospects for Enhancing Reproductive Efficiency.

Published in:

Animals (2076-2615), 2025, v. 15, n. 13, p. 2000, doi. 10.3390/ani15132000

By:

Zhang, Yi-Ran;
Xu, De-Jun

Publication type:

Article

Alcohol Consumption and Liver Metabolism in the Era of MASLD: Integrating Nutritional and Pathophysiological Insights.

Published in:

Nutrients, 2025, v. 18, n. 13, p. 2229, doi. 10.3390/nu17132229

By:

Acierno, Carlo;
Barletta, Fannia;
Caturano, Alfredo;
Nevola, Riccardo;
Sasso, Ferdinando Carlo;
Adinolfi, Luigi Elio;
Rinaldi, Luca

Publication type:

Article

PEMFs Restore Mitochondrial and CREB/BDNF Signaling in Oxidatively Stressed PC12 Cells Targeting Neurodegeneration.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6495, doi. 10.3390/ijms26136495

By:

Merighi, Stefania;
Fernandez, Mercedes;
Nigro, Manuela;
Travagli, Alessia;
Caldon, Filippo;
Salati, Simona;
Borea, Pier Andrea;
Cadossi, Ruggero;
Varani, Katia;
Gessi, Stefania

Publication type:

Article

The Role of Mitochondrial Dysfunction and Oxidative Stress in Women's Reproductive Disorders: Implications for Polycystic Ovary Syndrome and Preeclampsia.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6439, doi. 10.3390/ijms26136439

By:

Deer, Evangeline;
LaMarca, Babbette;
Reckelhoff, Jane F.;
Shawky, Noha M.;
Edwards, Kristin

Publication type:

Article

Oxidative Stress and Mitochondrial Dysfunction in Myelodysplastic Syndrome: Roles in Development, Diagnosis, Prognosis, and Treatment.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6415, doi. 10.3390/ijms26136415

By:

Pierro, Federico;
Fazio, Manlio;
Murdaca, Giuseppe;
Stagno, Fabio;
Gangemi, Sebastiano;
Allegra, Alessandro

Publication type:

Article

Connecting the Dots: Mitochondrial Dysfunction, PCOS, and Insulin Resistance—Insights and Therapeutic Advances.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6233, doi. 10.3390/ijms26136233

By:

Tharayil, Samia Palat;
Shukla, Pallavi

Publication type:

Article

Estradiol Prevents Amyloid Beta-Induced Mitochondrial Dysfunction and Neurotoxicity in Alzheimer's Disease via AMPK-Dependent Suppression of NF-κB Signaling.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6203, doi. 10.3390/ijms26136203

By:

Mishra, Pranav;
Esfahani, Ehsan K.;
Fernyhough, Paul;
Albensi, Benedict C.

Publication type:

Article

Highlights of 2024: Tregs immunometabolism and how to counter inflammatory niches.

Published in:

Immunology & Cell Biology, 2025, v. 103, n. 6, p. 504, doi. 10.1111/imcb.70027

By:

Valentini, Nicolas;
Requejo Cier, Christopher J;
Lamarche, Caroline

Publication type:

Article

Hyperglycemia-induced mitochondrial abnormalities in autonomic neurons via the RAGE axis.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-10933-y

By:

Otero, María G.;
Henao-Romero, Nicolas;
Krysak, Trevor M.;
Vu-Lu, Minh T.;
Morales, Oscar O. Morales;
Momeni, Zeinab;
Yamamoto, Yasuhiko;
Falzone, Tomas L.;
Campanucci, Verónica A.

Publication type:

Article

Mitochondrial dysfunction in children with chronic kidney disease.

Published in:

Pamukkale Medical Journal, 2025, v. 18, n. 3, p. 626, doi. 10.31362/patd.1658979

By:

Girişgen, İlknur;
Avcı, Esin

Publication type:

Article

NEW HORIZONS IN THE TREATMENT OF MITOCHONDRIAL NEUROGASTROINTESTINAL ENCEPHALOMYOPATHY (MNGIE): FROM PATHOGENESIS TO THERAPIES.

Published in:

Folia Pomeranae Universitatis Technologiae Stetinensis Agricultura Alimentaria Piscaria et Zootechnica, 2025, v. 375, n. 74, p. 64, doi. 10.21005/AAPZ2025.73.1.6

By:

TRZMIEL, Dominika

Publication type:

Article

Oxidative stress in ARDS: mechanisms and therapeutic potential.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1603287

By:

Wang, Fengyun;
Ge, Ruiqi;
Cai, Yun;
Zhao, Mingrui;
Fang, Zhen;
Li, Jingguo;
Xie, Chengzhi;
Wang, Mei;
Li, Wanyue;
Wang, Xiaozhi

Publication type:

Article

P.083 A novel mutation in YARS2 gene in a patient with MLASA.

Published in:

2025

By:

Eisenkoelbl, A;
Carter, M;
McMillan, H

Publication type:

Abstract

O-prenylchalcones inhibit cell proliferation and activate apoptosis by inducing mitochondrial dysfunction in gastric cancer cells.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-03130-w

By:

Espinoza-Hicks, José C.;
Salinas-Vera, Yarely M.;
Camarillo-Cisneros, Javier;
Camacho-Dávila, Alejandro A.;
Hernández-Rivera, Jessica L.;
Flores-Huerta, Nadia;
Ibarra-Sierra, Eloisa;
Pérez-Plasencia, Carlos;
Álvarez-Sánchez, María Elizbeth;
Tecalco-Cruz, Ángeles C.;
López-Camarillo, César

Publication type:

Article

Increased Reactive Oxygen Species and Distinct Oxidative Damage in Resveratrol-suppressed Glioblastoma Cells.

Published in:

Journal of Cancer, 2021, v. 12, n. 1, p. 141, doi. 10.7150/jca.45489

By:

Bin Jia;
Xu Zheng;
Mo-Li Wu;
Xiao-Ting Tian;
Xue Song;
Yan-Na Liu;
Pei-Nan Li;
Jia Liu

Publication type:

Article

The role of natural products in improving lipid metabolism disorder-induced mitochondrial dysfunction of diabetic kidney disease.

Published in:

Frontiers in Physiology, 2025, p. 1, doi. 10.3389/fphys.2025.1624077

By:

Deng, Yingping;
Zhu, Han;
Xing, Jie;
Gao, Junwei;
Duan, Jiamin;
Liu, Peng;
Zhong, Guanghui;
Cai, Xudong

Publication type:

Article

Adipose tissue dysfunction disrupts metabolic homeostasis: mechanisms linking fat dysregulation to disease.

Published in:

Frontiers in Endocrinology, 2025, p. 1, doi. 10.3389/fendo.2025.1592683

By:

Bou Matar, Dana;
Zhra, Mahmoud;
Nassar, Walid Khaled;
Altemyatt, Haifa;
Naureen, Asfiya;
Abotouk, Nada;
Elahi, Muhammad Affan;
Aljada, Ahmad

Publication type:

Article

6-Methoxydihydroavicine is a benzophenanthridine alkaloid with anti-leukemia activity.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1621050

By:

Yang, Yingying;
Spagnuolo, Paul A.

Publication type:

Article

Extremely low-frequency electromagnetic field (ELF-EMF) enhances mitochondrial energy production in NARP cybrids.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-10536-7

By:

Ito, Mikako;
Huang, Zhizhou;
Nomura, Kosaku;
Teranishi, Masaki;
Zhao, Fei;
Mino, Hiroyuki;
Yoneda, Makoto;
Tanaka, Masashi;
Ohno, Kinji

Publication type:

Article

Spectrum of clinical neuroimaging in mitochondrial disorders: a neuroanatomical approach.

Published in:

Pediatric Radiology, 2025, v. 55, n. 7, p. 1350, doi. 10.1007/s00247-025-06252-z

By:

Kielty, Kate;
Collyer, John;
Ganesh, Krrithvi Dharini;
Narayanan, Srikala;
Rajan, Deepa S.

Publication type:

Article

Modulating Ferroptosis in Aging: The Therapeutic Potential of Natural Products.

Published in:

Journal of Aging Research, 2025, v. 2025, p. 1, doi. 10.1155/jare/8832992

By:

Hamidu, Sherif;
Amponsah, Seth Kwabena;
Aning, Abigail;
Adams, Latif;
Kumi, Justice;
Ampem-Danso, Eunice;
Hamidu, Fatima;
Mumin Mohammed, Mustapha Abdul;
Ador, Gabriel Tettey;
Khatun, Sanjida;
Siva Kumar, Udhaya Kumar

Publication type:

Article

Novel ANKRD17 variants implicate synaptic and mitochondrial disruptions in intellectual disability and autism spectrum disorder.

Published in:

Journal of Neurodevelopmental Disorders, 2025, v. 17, n. 1, p. 1, doi. 10.1186/s11689-025-09619-3

By:

Xia, Dan;
Xu, Yuanyuan;
He, Zhanwen;
Chen, Rui;
Xiao, Xiaoqin;
Li, Xiaojuan;
Deng, Kewen;
Deng, Shuyun;
Zhang, Lina;
Zhang, Jieming;
Peng, Xiaofang;
Meng, Zhe;
Wu, Ruohao;
Wang, Dilong;
Liu, Zulin;
Chen, Hui;
Li, Lu;
Liang, Liyang

Publication type:

Article

Expanding the Phenotypic Spectrum of SPG7 Rare Damaging Variants: Insights From a Hungarian Cohort.

Published in:

Clinical Genetics, 2025, v. 108, n. 2, p. 124, doi. 10.1111/cge.14719

By:

Jimoh, Idris Janos;
Balicza, Peter;
Szlepak, Tamas;
Csaban, Dora;
Gal, Aniko;
Geresi, Adrienn;
Grosz, Zoltan;
Palasti, Agnes;
Boczan, Judit;
Klivenyi, Peter;
Molnar, Maria Judit

Publication type:

Article

Current strategies in the management of dementia with lewy bodies and future directions based on disease pathophysiology.

Published in:

Molecular Neurodegeneration, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13024-025-00856-7

By:

Erskine, Daniel;
Taylor, John-Paul

Publication type:

Article

The Anatomical and Evolutionary Impact of Pain, Pleasure, Motivation, and Cognition: Integrating Energy Metabolism and the Mind–Body BERN (Behavior, Exercise, Relaxation, and Nutrition) Framework.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5491, doi. 10.3390/ijms26125491

By:

Stefano, George B.;
Buttiker, Pascal;
Michaelsen, Maren M.;
Esch, Tobias

Publication type:

Article

Anesthetic considerations in patients with mitochondrial defects.

Published in:

Pediatric Anesthesia, 2013, v. 23, n. 9, p. 785, doi. 10.1111/pan.12158

By:

Niezgoda, Julie;
Morgan, Phil G.

Publication type:

Article

Bax Activation Initiates the Assembly of a Multimeric Catalyst that Facilitates Bax Pore Formation in Mitochondrial Outer Membranes.

Published in:

PLoS Biology, 2012, v. 10, n. 9, p. 1, doi. 10.1371/journal.pbio.1001394

By:

Kushnareva, Yulia;
Andreyev, Alexander Y.;
Kuwana, Tomomi;
Newmeyer, Donald D.

Publication type:

Article

The Roles of PINK1 and Parkin in Parkinson's Disease.

Published in:

PLoS Biology, 2010, v. 8, n. 1, p. 1, doi. 10.1371/journal.pbio.1000299

By:

Jones, Rachel

Publication type:

Article

Mitochondrial Dysfunction Accounts for the Stochastic Heterogeneity in Telomere-Dependent Senescence.

Published in:

PLoS Biology, 2007, v. 5, n. 5, p. e110, doi. 10.1371/journal.pbio.0050110

By:

Passos, João F.;
Saretzki, Gabriele;
Ahmed, Shaheda;
Nelson, Glyn;
Richter, Torsten;
Peters, Heiko;
Wappler, Ilka;
Birket, Matthew J.;
Harold, Graham;
Schaeuble, Karin;
Birch-Machin, Mark A.;
Kirkwood, Thomas B. L.;
von Zglinicki, Thomas

Publication type:

Article

A New Role for a Protein Involved in Energy Metabolism.

Published in:

PLoS Biology, 2005, v. 3, n. 4, p. 550, doi. 10.1371/journal.pbio.0030133

By:

Leone, T. C.;
Lehman, J. J.;
Finck, b. N.;
Schaeffer, P. J.;
Wende, A. R.

Publication type:

Article

Integrative Analysis of the Mitochondrial Proteome in Yeast.

Published in:

PLoS Biology, 2004, v. 2, n. 6, p. 1, doi. 10.1371/journal.pbio.0020160

By:

Prokisch, Holger;
Scharfe, Curt;
Camp II, David G;
Xiao, Wenzhong;
David, Lior;
Andreoli, Christophe;
Monroe, Matthew E;
Moore, Ronald J;
Gritsenko, Marina A;
Kozany, Christian;
Hixson, Kim K;
Mottaz, Heather M;
Zischka, Hans;
Ueffing, Marius;
Herman, Zelek S;
Davis, Ronald W;
Meitinger, Thomas;
Oefner, Peter J;
Smith, Richard D;
Steinmetz, Lars M

Publication type:

Article

Becoming a Rare Disease Parent: An Interpretative Phenomenological Analysis of Parent-Caregivers' Postpartum Experiences.

Published in:

Qualitative Health Research, 2024, v. 34, n. 1/2, p. 126, doi. 10.1177/10497323231205419

By:

Davidson, Hannah Rochelle;
Gelles, Shani;
Keller, Krystyna R.;
Zajdel, Melissa;
Koehly, Laura M.

Publication type:

Article

Acetaminophen hepatotoxicity and repair: the role of sterile inflammation and innate immunity.

Published in:

Liver International, 2012, v. 32, n. 1, p. 8, doi. 10.1111/j.1478-3231.2011.02501.x

By:

Jaeschke, Hartmut;
Williams, C. David;
Ramachandran, Anup;
Bajt, Mary L.

Publication type:

Article

Mitochondrial DNA dysfunction in oncocytic hepatocytes.

Published in:

Liver International, 2003, v. 23, n. 5, p. 397, doi. 10.1034/j.1478-3231.2003.00864.x

By:

Tanji, Kurenai;
Bhagat, Govind;
Vu, Tuan H.;
Monzon, Lailani;
Bonilla, Eduardo;
Lefkowitch, Jay H.

Publication type:

Article

ATP5A1 and ATP5B are highly expressed in glioblastoma tumor cells and endothelial cells of microvascular proliferation.

Published in:

Journal of Neuro-Oncology, 2016, v. 126, n. 3, p. 405, doi. 10.1007/s11060-015-1984-x

By:

Xu, Guiyan;
Li, Jian

Publication type:

Article

Co-administration of ABT-737 and SAHA induces apoptosis, mediated by Noxa upregulation, Bax activation and mitochondrial dysfunction in PTEN-intact malignant human glioma cell lines.

Published in:

Journal of Neuro-Oncology, 2014, v. 120, n. 3, p. 459, doi. 10.1007/s11060-014-1575-2

By:

Foster, Kimberly;
Jane, Esther;
Premkumar, Daniel;
Morales, Alejandro;
Pollack, Ian

Publication type:

Article

Interactions among mitochondrial proteins altered in glioblastoma.

Published in:

Journal of Neuro-Oncology, 2014, v. 118, n. 2, p. 247, doi. 10.1007/s11060-014-1430-5

By:

Deighton, Ruth;
Bihan, Thierry;
Martin, Sarah;
Gerth, Alice;
McCulloch, Mailis;
Edgar, Julia;
Kerr, Lorraine;
Whittle, Ian;
McCulloch, James

Publication type:

Article

Metabolic Imaging Using Two-Photon Excited NADH Intensity and Fluorescence Lifetime Imaging.

Published in:

Microscopy & Microanalysis, 2012, v. 18, n. 4, p. 761, doi. 10.1017/S1431927612000529

By:

Vergen, Jorge;
Hecht, Clifford;
Zholudeva, Lyandysha V.;
Marquardt, Meg M.;
Hallworth, Richard;
Nichols, Michael G.

Publication type:

Article

Mitochondrial Abnormalities in Alzheimer Disease.

Published in:

2011

By:

Perry, G;
Wang, X;
Smith, M;
Zhu, X

Publication type:

Abstract