Works matching DE "MICROPHYSIOLOGICAL systems"

Results: 303

Chromogranin A deficiency attenuates tauopathy by altering epinephrine–alpha-adrenergic receptor signaling in PS19 mice.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-59682-6

By:

Jati, Suborno;
Munoz-Mayorga, Daniel;
Shahabi, Shandy;
Tang, Kechun;
Tao, Yuren;
Dickson, Dennis W.;
Litvan, Irene;
Ghosh, Gourisankar;
Mahata, Sushil K.;
Chen, Xu

Publication type:

Article

Mucinous breast cancer organoids: an in vitro research model.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02586-0

By:

Zhao, Dongyi;
Zhu, Shida;
Bai, Xue;
Li, Xuelu;
Zhao, Zuowei

Publication type:

Article

Unveiling metabolic pathways in the hyperglycemic bone: bioenergetic and proteomic analysis of the bone tissue exposed to acute and chronic high glucose.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01251-0

By:

Araújo, Rita;
Bernardino, Raquel L.;
Monteiro, Mariana P.;
Gomes, Pedro S.

Publication type:

Article

Human and rat renal proximal tubule in vitro models for ADME applications.

Published in:

Archives of Toxicology, 2025, v. 99, n. 5, p. 1613, doi. 10.1007/s00204-025-03987-4

By:

Klatt, Olivia C.;
de Brouwer, Lenya;
Hendriks, Femke;
Dehne, Eva-Maria;
Ataç Wagegg, Beren;
Jennings, Paul;
Wilmes, Anja

Publication type:

Article

An eighteen-organ microphysiological system coupling a vascular network and excretion system for drug discovery.

Published in:

Microsystems & Nanoengineering, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41378-025-00933-3

By:

Wang, Jing;
Zhang, Huixue;
Qu, Yueyang;
Yang, Yang;
Xu, Shuhui;
Ji, Zhenni;
Wang, Yuxiu;
Zhang, Xiuli;
Luo, Yong

Publication type:

Article

Advancing Organ-on-a-Chip Systems: The Role of Scaffold Materials and Coatings in Engineering Cell Microenvironment.

Published in:

Polymers (20734360), 2025, v. 17, n. 9, p. 1263, doi. 10.3390/polym17091263

By:

Ramírez-González, Guido Andrés;
Consumi-Tubito, Chiara;
Vargas-Méndez, Ernesto;
Centeno-Cerdas, Carolina

Publication type:

Article

Development of a reliable method for human triple-negative breast cancer organotypic culture: Improving imaging and genomic studies in 3D cultures.

Published in:

Journal of Tissue Engineering, 2025, p. 1, doi. 10.1177/20417314251326668

By:

Olvera-Valencia, Mercedes;
Garcia-Castillo, Verónica;
Ramos-Payan, Rosalío;
Aguilar-Medina, Maribel;
Trujano-Camacho, Samuel;
López-Saavedra, Alejandro;
Marchat, Laurence A.;
López-Camarillo, Cesar;
Sumagin, Ronen;
Pérez-Yepez, Eloy;
Pérez-Plasencia, Carlos

Publication type:

Article

生体模倣システムを活用したがん微小環境の細胞/物質動態研究.

Published in:

Folia Pharmacologica Japonica, 2025, v. 160, n. 2, p. 97, doi. 10.1254/fpj.24063

By:

梨本裕司

Publication type:

Article

神経系MPSの可能性.

Published in:

Folia Pharmacologica Japonica, 2025, v. 160, n. 2, p. 92, doi. 10.1254/fpj.24098

By:

鈴木郁郎

Publication type:

Article

Microphysiological systems (MPS)に関する国内外の最新動向一心臓MPSにも触れて一.

Published in:

Folia Pharmacologica Japonica, 2025, v. 160, n. 2, p. 87, doi. 10.1254/fpj.24070

By:

山崎大樹

Publication type:

Article

A novel three-dimensional model of infantile haemangioma.

Published in:

British Journal of Dermatology, 2025, v. 192, n. 5, p. 874, doi. 10.1093/bjd/ljae483

By:

Mitra, Raka;
Hale, Tracy K;
Fitzsimons, Helen L;
Gray, Clint;
White, Madeleine P J

Publication type:

Article

Ongoing loss of viable neurons for weeks after mild hypoxia-ischaemia.

Published in:

Brain Communications, 2025, v. 7, n. 2, p. 1, doi. 10.1093/braincomms/fcaf153

By:

McNally, Melanie A;
Lau, Lauren A;
Granak, Simon;
Hike, David;
Liu, Xiaochen;
Yu, Xin;
Donahue, Rachel A;
Chibnik, Lori B;
Ortiz, John V;
Che, Alicia;
Chavez-Valdez, Raul;
Northington, Frances J;
Staley, Kevin J

Publication type:

Article

The inflammatory APRIL (a proliferation-inducing ligand) antagonizes chondroitin sulphate proteoglycans to promote axonal growth and myelination.

Published in:

Brain Communications, 2025, v. 7, n. 1, p. 1, doi. 10.1093/braincomms/fcae473

By:

Ahmed, Mashal Claude;
Kakunuri, Tejaswini;
Peris, Leticia;
Meffre, Delphine;
Yilmaz, Elif Nur;
Grewing, Laureen;
González, Raquel Guerrero;
Manfroi, Benoit;
Gout, Evelyne;
Vivès, Romain R;
Fitzgerald, Una;
Schneider, Pascal;
Jafarian-Tehrani, Mehrnaz;
Kuhlmann, Tanja;
Huard, Bertrand

Publication type:

Article

An engineered human placental organoid microphysiological system in a vascular niche to model viral infection.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-08057-0

By:

Wang, Yaqing;
Guo, Yaqiong;
Wang, Peng;
Liu, Jiayue;
Zhang, Xu;
Liu, Qian;
Wei, Lin;
Xu, Cong;
Qin, Jianhua

Publication type:

Article

Complementary Metal Oxide Semiconductor-Based Optical Detection System for Fluidic Cellular Medium pH Quantification.

Published in:

Photonics, 2024, v. 11, n. 12, p. 1130, doi. 10.3390/photonics11121130

By:

Santos, André A.;
Ferreira, Gabriel M.;
Sousa, Paulo J.;
Sousa, Patrícia C.;
Catarino, Susana O.;
Minas, Graça

Publication type:

Article

Highly scalable and standardized organ-on-chip platform with TEER for biological barrier modeling.

Published in:

Tissue Barriers, 2024, v. 12, n. 4, p. 1, doi. 10.1080/21688370.2024.2315702

By:

Nguyen, Hoang-Tuan;
Rissanen, Siiri-Liisa;
Peltokangas, Mimosa;
Laakkonen, Tino;
Kettunen, Jere;
Barthod, Lara;
Sivakumar, Ragul;
Palojärvi, Anniina;
Junttila, Pauliina;
Talvitie, Jussi;
Bassis, Michele;
Nickels, Sarah L.;
Kalvala, Sara;
Ilina, Polina;
Tammela, Päivi;
Lehtonen, Sarka;
Schwamborn, Jens C.;
Mosser, Sebastien;
Singh, Prateek

Publication type:

Article

Models for barrier understanding in health and disease in lab-on-a-chips.

Published in:

Tissue Barriers, 2024, v. 12, n. 2, p. 1, doi. 10.1080/21688370.2023.2221632

By:

Ponmozhi, J.;
Dhinakaran, S.;
Kocsis, Dorottya;
Iván, Kristóf;
Erdõ, Franciska

Publication type:

Article

Chemical Suppression of KLK5 and KLK7 Rescues Barrier Integrity in a Netherton Syndrome Model.

Published in:

Experimental Dermatology, 2025, v. 34, n. 2, p. 1, doi. 10.1111/exd.70055

By:

Yeo, Shi Yun;
Low, Tanya;
Fernandis, Aaron Zefrin

Publication type:

Article

CLDN1 knock out keratinocytes as a model to investigate multiple skin disorders.

Published in:

Experimental Dermatology, 2024, v. 33, n. 5, p. 1, doi. 10.1111/exd.15084

By:

Arnold, Kimberly A.;
Moran, Mary C.;
Shi, Huishan;
van Vlijmen‐Willems, Ivonne M. J. J.;
Rodijk‐Olthuis, Diana;
Smits, Jos P. H.;
Brewer, Matthew G.

Publication type:

Article

The critical role of neutrophil-endothelial cell interactions in sepsis: new synergistic approaches employing organ-on-chip, omics, immune cell phenotyping and in silico modeling to identify new therapeutics.

Published in:

Frontiers in Cellular & Infection Microbiology, 2024, p. 01, doi. 10.3389/fcimb.2023.1274842

By:

Liu, Dan;
Langston, Jordan C.;
Prabhakarpandian, Balabhaskar;
Kiani, Mohammad F.;
Kilpatrick, Laurie E.

Publication type:

Article

Innervation of the musculoskeletal system in physiological and pathological conditions: Insights from organ-on-a-chip models.

Published in:

Chemical Industry / Hemijska Industrija, 2024, v. 78, p. 12

By:

Lamghari, Meriem

Publication type:

Article

Translational studies of engineered human tissues.

Published in:

Chemical Industry / Hemijska Industrija, 2024, v. 78, p. 3

By:

Vunjak-Novakovic, Gordana

Publication type:

Article

A microfluidic platform integrating functional vascularized organoids-on-chip.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-45710-4

By:

Quintard, Clément;
Tubbs, Emily;
Jonsson, Gustav;
Jiao, Jie;
Wang, Jun;
Werschler, Nicolas;
Laporte, Camille;
Pitaval, Amandine;
Bah, Thierno-Sidy;
Pomeranz, Gideon;
Bissardon, Caroline;
Kaal, Joris;
Leopoldi, Alexandra;
Long, David A.;
Blandin, Pierre;
Achard, Jean-Luc;
Battail, Christophe;
Hagelkruys, Astrid;
Navarro, Fabrice;
Fouillet, Yves

Publication type:

Article

A microfluidic platform integrating functional vascularized organoids-on-chip.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-45710-4

By:

Quintard, Clément;
Tubbs, Emily;
Jonsson, Gustav;
Jiao, Jie;
Wang, Jun;
Werschler, Nicolas;
Laporte, Camille;
Pitaval, Amandine;
Bah, Thierno-Sidy;
Pomeranz, Gideon;
Bissardon, Caroline;
Kaal, Joris;
Leopoldi, Alexandra;
Long, David A.;
Blandin, Pierre;
Achard, Jean-Luc;
Battail, Christophe;
Hagelkruys, Astrid;
Navarro, Fabrice;
Fouillet, Yves

Publication type:

Article

Establishing Pancreatic Cancer Organoids from EUS-Guided Fine-Needle Biopsy Specimens.

Published in:

Cancers, 2025, v. 17, n. 4, p. 692, doi. 10.3390/cancers17040692

By:

Wang, Mei-Juan;
Gao, Chao;
Huang, Xin;
Wang, Min;
Zhang, Shuai;
Gao, Xiao-Pei;
Zhong, Chang-Qing;
Li, Lian-Yong

Publication type:

Article

Global Literature Analysis of Tumor Organoid and Tumor-on-Chip Research.

Published in:

Cancers, 2025, v. 17, n. 1, p. 108, doi. 10.3390/cancers17010108

By:

Shoji, Jun-ya;
Davis, Richard P.;
Mummery, Christine L.;
Krauss, Stefan

Publication type:

Article

Ex Vivo Intestinal Organoid Models: Current State-of-the-Art and Challenges in Disease Modelling and Therapeutic Testing for Colorectal Cancer.

Published in:

Cancers, 2024, v. 16, n. 21, p. 3664, doi. 10.3390/cancers16213664

By:

Randall-Demllo, Sarron;
Al-Qadami, Ghanyah;
Raposo, Anita E.;
Ma, Chenkai;
Priebe, Ilka K.;
Hor, Maryam;
Singh, Rajvinder;
Fung, Kim Y. C.

Publication type:

Article

Development of a Bladder Cancer-on-a-Chip Model to Assess Bladder Cancer Cell Invasiveness.

Published in:

Cancers, 2024, v. 16, n. 15, p. 2657, doi. 10.3390/cancers16152657

By:

Ewell, Desiree J.;
Vue, Nita;
Moinuddin, Sakib M.;
Sarkar, Tanoy;
Ahsan, Fakhrul;
Vinall, Ruth L.

Publication type:

Article

Advances in 3D Culture Models to Study Exosomes in Triple-Negative Breast Cancer.

Published in:

Cancers, 2024, v. 16, n. 5, p. 883, doi. 10.3390/cancers16050883

By:

Yousafzai, Neelum Aziz;
El Khalki, Lamyae;
Wang, Wei;
Szpendyk, Justin;
Sossey-Alaoui, Khalid

Publication type:

Article

Human Intestinal Organoids and Microphysiological Systems for Modeling Radiotoxicity and Assessing Radioprotective Agents.

Published in:

Cancers, 2023, v. 15, n. 24, p. 5859, doi. 10.3390/cancers15245859

By:

Bouges, Eloïse;
Segers, Charlotte;
Leys, Natalie;
Lebeer, Sarah;
Zhang, Jianbo;
Mastroleo, Felice

Publication type:

Article

Organ-on-a-Chip and Microfluidic Platforms for Oncology in the UK.

Published in:

Cancers, 2023, v. 15, n. 3, p. 635, doi. 10.3390/cancers15030635

By:

Nolan, Joanne;
Pearce, Oliver M. T.;
Screen, Hazel R. C.;
Knight, Martin M.;
Verbruggen, Stefaan W.

Publication type:

Article

Advanced Cellular Models for Preclinical Drug Testing: From 2D Cultures to Organ-on-a-Chip Technology.

Published in:

Cancers, 2022, v. 14, n. 15, p. 3692, doi. 10.3390/cancers14153692

By:

Foglizzo, Valentina;
Cocco, Emiliano;
Marchiò, Serena

Publication type:

Article

Engineered Microphysiological Systems for Testing Effectiveness of Cell-Based Cancer Immunotherapies.

Published in:

Cancers, 2022, v. 14, n. 15, p. 3561, doi. 10.3390/cancers14153561

By:

Campisi, Marco;
Shelton, Sarah E.;
Chen, Minyue;
Kamm, Roger D.;
Barbie, David A.;
Knelson, Erik H.

Publication type:

Article

Organ-on-a-Chip Platforms for Drug Screening and Delivery in Tumor Cells: A Systematic Review.

Published in:

Cancers, 2022, v. 14, n. 4, p. 935, doi. 10.3390/cancers14040935

By:

Gonçalves, Inês M.;
Carvalho, Violeta;
Rodrigues, Raquel O.;
Pinho, Diana;
Teixeira, Senhorinha F. C. F.;
Moita, Ana;
Hori, Takeshi;
Kaji, Hirokazu;
Lima, Rui;
Minas, Graça

Publication type:

Article

The Advances in Glioblastoma On-a-Chip for Therapy Approaches.

Published in:

Cancers, 2022, v. 14, n. 4, p. 869, doi. 10.3390/cancers14040869

By:

Alves, Arielly H.;
Nucci, Mariana P.;
Mamani, Javier B.;
Valle, Nicole M. E.;
Ribeiro, Eduarda F.;
Rego, Gabriel N. A.;
Oliveira, Fernando A.;
Theinel, Matheus H.;
Santos, Ricardo S.;
Gamarra, Lionel F.

Publication type:

Article

Organ-Chip Models: Opportunities for Precision Medicine in Pancreatic Cancer.

Published in:

Cancers, 2021, v. 13, n. 17, p. 4487, doi. 10.3390/cancers13174487

By:

Haque, Muhammad R.;
Rempert, Trevor H.;
Al-Hilal, Taslim A.;
Wang, Chengyao;
Bhushan, Abhinav;
Bishehsari, Faraz

Publication type:

Article

Electrochemical Sensing in 3D Cell Culture Models: New Tools for Developing Better Cancer Diagnostics and Treatments.

Published in:

Cancers, 2021, v. 13, n. 6, p. 1381, doi. 10.3390/cancers13061381

By:

Oliveira, Micaela;
Conceição, Pedro;
Kant, Krishna;
Ainla, Alar;
Diéguez, Lorena;
Rodrigues, Raquel;
Minas, Graça;
Krauss, Stefan

Publication type:

Article

Microfluidic Organoids-on-a-Chip: Quantum Leap in Cancer Research.

Published in:

Cancers, 2021, v. 13, n. 4, p. 737, doi. 10.3390/cancers13040737

By:

Duzagac, Fahriye;
Saorin, Gloria;
Memeo, Lorenzo;
Canzonieri, Vincenzo;
Rizzolio, Flavio;
Piché, Alain

Publication type:

Article

Engineering growth factor gradients to drive spatiotemporal tissue patterning in organ-on-a-chip systems.

Published in:

Journal of Tissue Engineering, 2025, p. 1, doi. 10.1177/20417314251326256

By:

Hopkins, Timothy;
Midha, Swati;
Grossemy, Simon;
Screen, Hazel R. C.;
Wann, Angus K. T.;
Knight, Martin M.

Publication type:

Article

Strategies to overcome the limitations of current organoid technology - engineered organoids.

Published in:

Journal of Tissue Engineering, 2025, p. 1, doi. 10.1177/20417314251319475

By:

Fan, Xulong;
Hou, Kun;
Liu, Gaojian;
Shi, Ruolin;
Wang, Wenjie;
Liang, Gaofeng

Publication type:

Article

Gum-on-a-Chip Exploring Host-Microbe Interactions: Periodontal Disease Modeling and Drug Discovery.

Published in:

Journal of Tissue Engineering, 2025, p. 1, doi. 10.1177/20417314251314356

By:

Hu, Qin;
Acharya, Aneesha;
Shum, Ho Cheung;
Leung, Wai Keung;
Pelekos, George

Publication type:

Article

From in vivo models to in vitro bioengineered neuromuscular junctions for the study of Charcot-Marie-Tooth disease.

Published in:

2025

By:

Scherrer, Camille;
Loret, Camille;
Védrenne, Nicolas;
Buckley, Colman;
Lia, Anne-Sophie;
Kermene, Vincent;
Sturtz, Franck;
Favreau, Frédéric;
Rovini, Amandine;
Faye, Pierre-Antoine

Publication type:

Literature Review

Divergent responses of human intestinal organoid monolayers using commercial in vitro cytotoxicity assays.

Published in:

PLoS ONE, 2024, v. 19, n. 6, p. 1, doi. 10.1371/journal.pone.0304526

By:

Lewis, Miranda A.;
Patil, Ketki;
Ettayebi, Khalil;
Estes, Mary K.;
Atmar, Robert L.;
Ramani, Sasirekha

Publication type:

Article

AngioMT: A MATLAB based 2D image-to-physics tool to predict oxygen transport in vascularized microphysiological systems.

Published in:

PLoS ONE, 2024, v. 19, n. 5, p. 1, doi. 10.1371/journal.pone.0299160

By:

Mathur, Tanmay;
Tronolone, James J.;
Jain, Abhishek

Publication type:

Article

Pancreatic 3D Organoids and Microfluidic Systems—Applicability and Utilization in Surgery: A Literature Review.

Published in:

Medicina (1010660X), 2025, v. 61, n. 4, p. 623, doi. 10.3390/medicina61040623

By:

Petrauskas, Vidas;
Damaseviciute, Ryte;
Gulla, Aiste

Publication type:

Article

State of the Art in 3D Culture Models Applied to Thyroid Cancer.

Published in:

Medicina (1010660X), 2024, v. 60, n. 4, p. 520, doi. 10.3390/medicina60040520

By:

Prete, Alessandro;
Matrone, Antonio;
Plebani, Roberto

Publication type:

Article

Preclinical translational platform of neuroinflammatory disease biology relevant to neurodegenerative disease.

Published in:

Journal of Neuroinflammation, 2024, v. 21, p. 1, doi. 10.1186/s12974-024-03029-3

By:

Larson, Kelley C.;
Martens, Lauren H.;
Marconi, Michael;
Dejesus, Christopher;
Bruhn, Suzanne;
Miller, Thomas A.;
Tate, Barbara;
Levenson, Jonathan M.

Publication type:

Article

Modeling the neuroimmune system in Alzheimer's and Parkinson's diseases.

Published in:

Journal of Neuroinflammation, 2024, v. 21, n. 1, p. 1, doi. 10.1186/s12974-024-03024-8

By:

Balestri, Wendy;
Sharma, Ruchi;
da Silva, Victor A.;
Bobotis, Bianca C.;
Curle, Annabel J.;
Kothakota, Vandana;
Kalantarnia, Farnoosh;
Hangad, Maria V.;
Hoorfar, Mina;
Jones, Joanne L.;
Tremblay, Marie-Ève;
El-Jawhari, Jehan J.;
Willerth, Stephanie M.;
Reinwald, Yvonne

Publication type:

Article

Organoids and 3D In Vitro Models as a Platform for Precision Medicine (PM): An Update.

Published in:

Organoids, 2024, v. 3, n. 3, p. 165, doi. 10.3390/organoids3030011

By:

Ganguly, Payal

Publication type:

Article

Research progress and future perspectives of tumor organoid.

Published in:

China Oncology, 2024, v. 34, n. 8, p. 763, doi. 10.19401/j.cnki.1007-3639.2024.08.006

By:

XIAO Yi;
WU Ming;
YAO Gang

Publication type:

Article