Works matching DE "METHYLTRANSFERASES"

Results: 3668

The impact of METTL3 on bladder cancer through m6A modification: a potential therapeutic target and prognostic biomarker.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1622117

By:

Wen, Dong;
Fu, Pengcheng;
Shuai, Geliu;
Wang, Yuebin;
Yu, Shengxin;
Liu, Huiquan;
Wan, Wei;
Zou, Junrong;
Zou, Xiaofeng

Publication type:

Article

NSUN2-mediated cytosine-5 methylation of FSP1 protects acute myeloid leukemia cells from ferroptosis.

Published in:

Molecular Cancer, 2025, v. 24, n. 1, p. 1, doi. 10.1186/s12943-025-02394-8

By:

Ye, Wenle;
Zhao, Yanchun;
Zhou, Yutong;
Huang, Jiansong;
He, Xiao;
Ma, Zhixin;
Huang, Xin;
Hu, Chao;
Li, Fenglin;
Ling, Qing;
Wang, Huafeng;
Tong, Hongyan;
Sun, Jie;
Jin, Jie

Publication type:

Article

NAMPT and NNMT released via extracellular vesicles and as soluble mediators are distinguished traits of BRAF inhibitor resistance of melanoma cells impacting on the tumor microenvironment.

Published in:

Cell Communication & Signaling, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12964-025-02361-2

By:

Ghezzi, Beatrice;
Fiorilla, Irene;
Carreira, Ágata;
Recco, Francesco;
Sorci, Leonardo;
Avalle, Lidia;
Ponzano, Alessia;
Mazzola, Francesca;
Todesco, Alberto Maria;
Tommasi, Nicoletta;
Gasparrini, Massimiliano;
D'Agostino, Vito Giuseppe;
Mignone, Flavio;
Provenzani, Alessandro;
Audrito, Valentina

Publication type:

Article

Arabidopsis PRMT5 buffers pre‐mRNA splicing and development against genetic variation in donor splice sites.

Published in:

New Phytologist, 2025, v. 247, n. 4, p. 1727, doi. 10.1111/nph.70293

By:

Beckel, Maximiliano S.;
San Martín, Abril;
Sánchez, Sabrina E.;
Seymour, Danelle K.;
de Leone, María José;
Careno, Daniel A.;
Mora‐García, Santiago;
Weigel, Detlef;
Yanovsky, Marcelo J.;
Chernomoretz, Ariel

Publication type:

Article

Multiple transactivation domains of EZH2 bind to the TAZ2 domain of p300 and stimulate the acetyltransferase function of p300.

Published in:

Biochemical Journal, 2025, v. 482, n. 13, p. 955, doi. 10.1042/BCJ20253037

By:

Becht, Dustin C.;
Biswas, Soumi;
Chenxi Xu;
Hongwen Xuan;
Khalil, Moustafa;
Ling Cai;
Musselman, Catherine A.;
Xin Liu;
Affar, El Bachir;
Xiaobing Shi;
Gang Greg Wang;
Kutateladze, Tatiana G.

Publication type:

Article

CX3CL1 promotes M1 macrophage polarization and osteoclast differentiation via NSUN5-mediated m5C modification.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-11046-2

By:

Deng, Zhibin;
Zhong, Wei

Publication type:

Article

METTL21A promotes hepatocellular carcinoma progression via methylating and stabilizing BAG3.

Published in:

NPJ Precision Oncology, 2025, v. 9, n. 1, p. 1, doi. 10.1038/s41698-025-01021-5

By:

Zhan, Ping;
Cheng, Yizhe;
Wu, Yingcan;
Lu, Jing;
Wen, Jing;
Chi, Xiaoqin;
Luo, Changhong;
Peng, Yiwei;
Chen, Xijun;
Wang, Fuqiang;
Yin, Zhenyu;
Xie, Chengrong

Publication type:

Article

The m6A modification of LINC01133 suppresses ER+ breast cancer progression by modulating IGF2BP2 protein stability via a ubiquitination-dependent mechanism.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1608574

By:

Li, Mai-dong;
Shan, Ben-jie;
Wang, Lei;
Gao, Shuang;
Hao, Li;
Yu, Hai-yang;
Pan, Yue-yin

Publication type:

Article

Methyltransferase 1-mediated tRNA N7-methylguanosine modification regulates dentin formation during tooth root development via p53 signaling.

Published in:

Journal of Bone & Mineral Research, 2025, v. 40, n. 6, p. 813, doi. 10.1093/jbmr/zjaf056

By:

Gan, Xinyan;
He, Kun;
Xiong, Qiuchan;
Sheng, Rui;
Lei, Kexin;
Jiang, Shuang;
Yang, Xiaoyu;
Cai, Yimeng;
Huang, Denghao;
Shi, Yu;
Ye, Ling;
Yuan, Quan;
Li, Qiwen

Publication type:

Article

Methylations with methanol via bioinspired catalytic C–O bond cleavage.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-61200-7

By:

Huang, Qing;
Xiang, Yao;
Wu, Yaqi;
Zheng, Yuzhu;
Liao, Rong-Zhen;
Xie, Youwei

Publication type:

Article

Evolutionary Dynamics of Plant TRM6/TRM61 Complexes.

Published in:

Plants (2223-7747), 2025, v. 14, n. 12, p. 1778, doi. 10.3390/plants14121778

By:

Yue, Wenjie;
Chen, Tong;
Liu, Shuyi;
Shi, Xiaowen

Publication type:

Article

Notizen aus der Forschung.

Published in:

Nachrichten aus der Chemie, 2025, v. 73, n. 7, p. 40, doi. 10.1002/nadc.20254151668

By:

Barra, Lena;
Calvino, Céline;
Dierkes, Georg;
Heine, Johanna;
Jahn, Ullrich;
Neudecker, Tim

Publication type:

Article

Bacterial pathogenesis: Legionella makes its mark on histones.

Published in:

Nature Reviews Microbiology, 2013, v. 11, n. 6, p. 359, doi. 10.1038/nrmicro3034

By:

Kåhrström, Christina Tobin

Publication type:

Article

Bacterial pathogenesis: Chlamydia gets a NUE look.

Published in:

Nature Reviews Microbiology, 2010, v. 8, n. 9, p. 614, doi. 10.1038/nrmicro2427

By:

Jermy, Andrew

Publication type:

Article

The phasevarion: phase variation of type III DNA methyltransferases controls coordinated switching in multiple genes.

Published in:

Nature Reviews Microbiology, 2010, v. 8, n. 3, p. 196, doi. 10.1038/nrmicro2283

By:

Srikhanta, Yogitha N.;
Fox, Kate L.;
Jennings, Michael P.

Publication type:

Article

Computational and Genetic Reduction of a Cell Cycle to Its Simplest, Primordial Components.

Published in:

PLoS Biology, 2013, v. 11, n. 12, p. 1, doi. 10.1371/journal.pbio.1001749

By:

Murray, Seán M.;
Panis, Gaël;
Fumeaux, Coralie;
Viollier, Patrick H.;
Howard, Martin

Publication type:

Article

Mouse PRDM9 DNA-Binding Specificity Determines Sites of Histone H3 Lysine 4 Trimethylation for Initiation of Meiotic Recombination.

Published in:

PLoS Biology, 2011, v. 9, n. 10, p. 1, doi. 10.1371/journal.pbio.1001176

By:

Grey, Corinne;
Barthès, Pauline;
Chauveau-Le Friec, Gaëlle;
Langa, Francina;
Baudat, Frédéric;
de Massy, Bernard

Publication type:

Article

The Leukemia-Associated Mllt10/Af10-Dot1l Are Tcf4/β- Catenin Coactivators Essential for Intestinal Homeostasis.

Published in:

PLoS Biology, 2010, v. 8, n. 11, p. 1, doi. 10.1371/journal.pbio.1000539

By:

Mahmoudi, Tokameh;
Boj, Sylvia F.;
Hatzis, Pantelis;
Li, Vivian S. W.;
Taouatas, Nadia;
Vries, Robert G. J.;
Teunissen, Hans;
Begthel, Harry;
Korving, Jeroen;
Mohammed, Shabaz;
Heck, Albert J. R.;
Clevers, Hans

Publication type:

Article

MLL2 Is Required in Oocytes for Bulk Histone 3 Lysine 4 Trimethylation and Transcriptional Silencing.

Published in:

PLoS Biology, 2010, v. 8, n. 8, p. 1, doi. 10.1371/journal.pbio.1000453

By:

Andreu-Vieyra, Claudia V.;
Ruihong Chen;
Agno, Julio E.;
Glaser, Stefan;
Anastassiadis, Konstantinos;
Stewart, A. Francis;
Matzuk, Martin M.

Publication type:

Article

The Testis-Specific Factor CTCFL Cooperates with the Protein Methyltransferase PRMT7 in H19 Imprinting Control Region Methylation.

Published in:

PLoS Biology, 2006, v. 4, n. 11, p. 1910, doi. 10.1371/journal.pbio.0040355

By:

Jelinic, Petar;
Stehle, Jean-Christophe;
Shaw, Phillip

Publication type:

Article

Distinct Mechanisms Determine Transposon Inheritance and Methylation via Small Interfering RNA and Histone Modification.

Published in:

PLoS Biology, 2003, v. 1, n. 3, p. 420, doi. 10.1371/journal.pbio.0000067

By:

Lippman, Zachary;
May, Bruce;
Yordan, Cristy;
Singer, Tatjana;
Martienssen, Rob

Publication type:

Article

Thiopurine S-methyltransferase gene polymorphism in Japanese patients with autoimmune liver diseases.

Published in:

Liver International, 2007, v. 27, n. 1, p. 95, doi. 10.1111/j.1478-3231.2006.01392.x

By:

Tamori, Akihiro;
Shinzaki, Mayumi;
Kosaka, Saori;
Hayashi, Takehiro;
Iwai, Shuji;
Enomoto, Masaru;
Habu, Daiki;
Sakaguchi, Hiroki;
Kawada, Norifumi;
Hino, Masayuki;
Shiomi, Susumu;
Nishiguchi, Shuhei

Publication type:

Article

Endometriotic mesenchymal stem cells promote the fibrosis process of endometriosis through paracrine TGF‐β1 mediated RASAL1 inhibition.

Published in:

Journal of Obstetrics & Gynaecology Research, 2024, v. 50, n. 3, p. 467, doi. 10.1111/jog.15851

By:

Feng, Ying;
Dong, Han;
Tan, Buzhen

Publication type:

Article

Defining a prognostic score based on O6-methylguanine-DNA methyltransferase cut-off methylation level determined by pyrosequencing in patients with glioblastoma multiforme.

Published in:

Journal of Neuro-Oncology, 2018, v. 140, n. 3, p. 559, doi. 10.1007/s11060-018-2981-7

By:

De Carlo, Elisa;
Gerratana, Lorenzo;
De Maglio, Giovanna;
Buoro, Vanessa;
Cortiula, Francesco;
Gurrieri, Lorena;
Isola, Miriam;
Fasola, Gianpiero;
Puglisi, Fabio;
Pizzolitto, Stefano;
Rizzato, Simona

Publication type:

Article

IDH mutation is associated with higher risk of malignant transformation in low-grade glioma.

Published in:

Journal of Neuro-Oncology, 2016, v. 127, n. 2, p. 363, doi. 10.1007/s11060-015-2048-y

By:

Leu, Severina;
Felten, Stefanie;
Frank, Stephan;
Boulay, Jean-Louis;
Mariani, Luigi

Publication type:

Article

Lower apparent diffusion coefficients indicate distinct prognosis in low-grade and high-grade glioma.

Published in:

Journal of Neuro-Oncology, 2014, v. 119, n. 2, p. 377, doi. 10.1007/s11060-014-1490-6

By:

Cui, Yong;
Ma, Li;
Chen, Xuzhu;
Zhang, Zhe;
Jiang, Haihui;
Lin, Song

Publication type:

Article

Management and survival rates in patients with glioma in China (2004-2010): a retrospective study from a single-institution.

Published in:

Journal of Neuro-Oncology, 2013, v. 113, n. 2, p. 259, doi. 10.1007/s11060-013-1103-9

By:

Yang, Pei;
Wang, Yongzhi;
Peng, Xiaoxia;
You, Gan;
Zhang, Wei;
Yan, Wei;
Bao, Zhaoshi;
Wang, Yinyan;
Qiu, Xiaoguang;
Jiang, Tao

Publication type:

Article

Efficacy of clinically relevant temozolomide dosing schemes in glioblastoma cancer stem cell lines.

Published in:

Journal of Neuro-Oncology, 2012, v. 109, n. 1, p. 45, doi. 10.1007/s11060-012-0878-4

By:

Beier, Dagmar;
Schriefer, Beate;
Brawanski, Konstantin;
Hau, Peter;
Weis, Joachim;
Schulz, Jörg;
Beier, Christoph

Publication type:

Article

Dose dense 1 week on/1 week off temozolomide in recurrent glioma: a retrospective study.

Published in:

Journal of Neuro-Oncology, 2012, v. 108, n. 1, p. 195, doi. 10.1007/s11060-012-0832-5

By:

Taal, Walter;
Segers-van Rijn, Joyce;
Kros, Johan;
Heuvel, Irene;
Rijt, Carin;
Bromberg, Jacoline;
Sillevis Smitt, Peter;
Bent, Martin

Publication type:

Article

Recent advances in the molecular understanding of glioblastoma.

Published in:

Journal of Neuro-Oncology, 2012, v. 108, n. 1, p. 11, doi. 10.1007/s11060-011-0793-0

By:

Bleeker, Fonnet;
Molenaar, Remco;
Leenstra, Sieger

Publication type:

Article

Prospective cohort study of radiotherapy with concomitant and adjuvant temozolomide chemotherapy for glioblastoma patients with no or minimal residual enhancing tumor load after surgery.

Published in:

Journal of Neuro-Oncology, 2012, v. 108, n. 1, p. 89, doi. 10.1007/s11060-012-0798-3

By:

Stummer, Walter;
Meinel, Thomas;
Ewelt, Christian;
Martus, Peter;
Jakobs, Olga;
Felsberg, Jörg;
Reifenberger, Guido

Publication type:

Article

Valproic acid sensitizes human glioma cells for temozolomide and γ-radiation.

Published in:

Journal of Neuro-Oncology, 2012, v. 107, n. 1, p. 61, doi. 10.1007/s11060-011-0725-z

By:

Nifterik, Krista;
den Berg, Jaap;
Slotman, Ben;
Lafleur, M.;
Sminia, Peter;
Stalpers, Lukas

Publication type:

Article

O-methylguanine-DNA methyltransferase promoter methylation in 45 primary central nervous system lymphomas: quantitative assessment of methylation and response to temozolomide treatment.

Published in:

Journal of Neuro-Oncology, 2012, v. 107, n. 1, p. 147, doi. 10.1007/s11060-011-0721-3

By:

Adachi, Jun-ichi;
Mishima, Kazuhiko;
Wakiya, Kenji;
Suzuki, Tomonari;
Fukuoka, Kohei;
Yanagisawa, Takaaki;
Matsutani, Masao;
Sasaki, Atsushi;
Nishikawa, Ryo

Publication type:

Article

The status of MGMT protein expression is a prognostic factor for meningeal hemangiopericytoma: a clinicopathologic and immunohistochemical study of 12 cases at a single institution.

Published in:

Journal of Neuro-Oncology, 2011, v. 105, n. 3, p. 563, doi. 10.1007/s11060-011-0620-7

By:

Chang, I-Wei;
Lin, Jui-Wei;
Wu, You-Ting

Publication type:

Article

Prognostic and predictive value of epigenetic silencing of MGMT in patients with high grade gliomas: a systematic review and meta-analysis.

Published in:

Journal of Neuro-Oncology, 2011, v. 105, n. 2, p. 325, doi. 10.1007/s11060-011-0594-5

By:

Olson, Robert;
Brastianos, Priscilla;
Palma, David

Publication type:

Article

Temozolomide and 13- cis retinoic acid in patients with anaplastic gliomas: a prospective single-arm monocentric phase-II study (RNOP-05).

Published in:

Journal of Neuro-Oncology, 2011, v. 104, n. 3, p. 801, doi. 10.1007/s11060-011-0548-y

By:

Grauer, Oliver;
Pascher, Christina;
Hartmann, Christian;
Zeman, Florian;
Weller, Michael;
Proescholdt, Martin;
Brawanski, Alexander;
Pietsch, Thorsten;
Wick, Wolfgang;
Bogdahn, Ulrich;
Hau, Peter

Publication type:

Article

Epigenetic regulation of DNA methyltransferases: DNMT1 and DNMT3B in gliomas.

Published in:

Journal of Neuro-Oncology, 2011, v. 104, n. 2, p. 483, doi. 10.1007/s11060-010-0520-2

By:

Rajendran, Ganeshkumar;
Shanmuganandam, Karthik;
Bendre, Ameya;
Mujumdar, Dattatreya;
Goel, Abhay;
Shiras, Anjali

Publication type:

Article

Erratum to: Epigenetic regulation of DNA methyltransferases: DNMT1 and DNMT3B in gliomas.

Published in:

2011

By:

Rajendran, Ganeshkumar;
Shanmuganandam, Karthik;
Bendre, Ameya;
Muzumdar, Dattatraya;
Goel, Abhay;
Shiras, Anjali

Publication type:

Correction Notice

A multicenter phase I trial of combination therapy with interferon-β and temozolomide for high-grade gliomas (INTEGRA study): the final report.

Published in:

Journal of Neuro-Oncology, 2011, v. 104, n. 2, p. 573, doi. 10.1007/s11060-011-0529-1

By:

Wakabayashi, Toshihiko;
Kayama, Takamasa;
Nishikawa, Ryo;
Takahashi, Hiroshi;
Hashimoto, Naoya;
Takahashi, Jun;
Aoki, Tomokazu;
Sugiyama, Kazuhiko;
Ogura, Masatoshi;
Natsume, Atsushi;
Yoshida, Jun

Publication type:

Article

Quantitative analysis of O-methylguanine DNA methyltransferase (MGMT) promoter methylation in patients with low-grade gliomas.

Published in:

Journal of Neuro-Oncology, 2011, v. 103, n. 2, p. 343, doi. 10.1007/s11060-010-0395-2

By:

Ochsenbein, Adrian;
Schubert, Adrian;
Vassella, Erik;
Mariani, Luigi

Publication type:

Article

Expression of O-methylguanine-DNA methyltransferase in childhood medulloblastoma.

Published in:

Journal of Neuro-Oncology, 2011, v. 103, n. 1, p. 59, doi. 10.1007/s11060-010-0366-7

By:

Faoro, Denis;
Bueren, André;
Shalaby, Tarek;
Sciuscio, Davide;
Hürlimann, Marie-Louise;
Arnold, Lucia;
Gerber, Nicolas;
Haybaeck, Johannes;
Mittelbronn, Michel;
Rutkowski, Stefan;
Hegi, Monika;
Grotzer, Michael

Publication type:

Article

Correlation between O-methylguanine-DNA methyltransferase and survival in elderly patients with glioblastoma treated with radiotherapy plus concomitant and adjuvant temozolomide.

Published in:

Journal of Neuro-Oncology, 2011, v. 102, n. 2, p. 311, doi. 10.1007/s11060-010-0324-4

By:

Minniti, Giuseppe;
Salvati, M.;
Arcella, A.;
Buttarelli, F.;
D'Elia, A.;
Lanzetta, G.;
Esposito, V.;
Scarpino, S.;
Maurizi Enrici, R.;
Giangaspero, F.

Publication type:

Article

O-methylguanine DNA methyltransferase status determined by promoter methylation and immunohistochemistry in gliosarcoma and their clinical implications.

Published in:

Journal of Neuro-Oncology, 2011, v. 101, n. 3, p. 477, doi. 10.1007/s11060-010-0267-9

By:

Kang, Shin-Hyuk;
Park, Kyung-Jae;
Kim, Chae-Yong;
Yu, Mi;
Park, Chul-Kee;
Park, Sung-Hye;
Chung, Yong-Gu

Publication type:

Article

Up-front temozolomide in elderly patients with anaplastic oligodendroglioma and oligoastrocytoma.

Published in:

Journal of Neuro-Oncology, 2011, v. 101, n. 3, p. 457, doi. 10.1007/s11060-010-0264-z

By:

Ducray, François;
Sierra del Rio, Monica;
Carpentier, Catherine;
Psimaras, Dimitri;
Idbaih, Ahmed;
Dehais, Caroline;
Kaloshi, Gentian;
Mokhtari, Karima;
Taillibert, Sophie;
Laigle-Donadey, Florence;
Omuro, Antonio;
Sanson, Marc;
Delattre, Jean-Yves;
Hoang-Xuan, Khê

Publication type:

Article

MGMT promoter methylation status in anaplastic meningiomas.

Published in:

2010

By:

Brokinkel, Benjamin;
Fischer, Bernhard;
Peetz-Dienhart, Susanne;
Ebel, Heinrich;
Sepehrnia, Abolghassem;
Rama, Burckhard;
Albert, Friedrich;
Stummer, Walter;
Paulus, Werner;
Hasselblatt, Martin

Publication type:

Letter

Low-dose fotemustine for recurrent malignant glioma: a multicenter phase II study.

Published in:

Journal of Neuro-Oncology, 2010, v. 100, n. 2, p. 209, doi. 10.1007/s11060-010-0163-3

By:

Fabi, Alessandra;
Metro, Giulio;
Vidiri, Antonello;
Lanzetta, Gaetano;
Carosi, Mariantonia;
Telera, Stefano;
Maschio, Marta;
Russillo, Michelangelo;
Sperduti, Isabella;
Carapella, Carmine;
Cognetti, Francesco;
Pace, Andrea

Publication type:

Article

Can high-dose fotemustine reverse MGMT resistance in glioblastoma multiforme?

Published in:

2010

By:

Gallo, Chiara;
Buonerba, Carlo;
Lorenzo, Giuseppe;
Romeo, Valeria;
Placido, Sabino;
Marinelli, Alfredo

Publication type:

Report

Primary CNS lymphoma in the elderly: temozolomide therapy and MGMT status.

Published in:

Journal of Neuro-Oncology, 2010, v. 97, n. 3, p. 389, doi. 10.1007/s11060-009-0032-0

By:

Kurzwelly, Delia;
Glas, Martin;
Roth, Patrick;
Weimann, Elke;
Lohner, Hanns;
Waha, Andreas;
Schabet, Martin;
Reifenberger, Guido;
Weller, Michael;
Herrlinger, Ulrich

Publication type:

Article

Phase II trial of temozolomide (TMZ) plus irinotecan (CPT-11) in adults with newly diagnosed glioblastoma multiforme before radiotherapy.

Published in:

Journal of Neuro-Oncology, 2009, v. 95, n. 3, p. 393, doi. 10.1007/s11060-009-9937-x

By:

Quinn, Jennifer A.;
Xiaoyin Jiang, Sara;
Reardon, David A.;
Desjardins, Annick;
Vredenburgh, James J.;
Friedman, Allan H.;
Sampson, John H.;
McLendon, Roger E.;
Herndon, James E.;
Friedman, Henry S.

Publication type:

Article

Prolonged and severe thrombocytopenia with pancytopenia induced by radiation-combined temozolomide therapy in a patient with newly diagnosed glioblastoma—analysis of O 6-methylguanine-DNA methyltransferase status.

Published in:

Journal of Neuro-Oncology, 2009, v. 92, n. 2, p. 227, doi. 10.1007/s11060-008-9754-7

By:

Motoo Nagane;
Kyoko Nozue;
Saki Shimizu;
Andreas Waha;
Hiroshi Miyazaki;
Hiroki Kurita;
Masashi Homori;
Yasunori Fujioka;
Yoshiaki Shiokawa

Publication type:

Article