Works matching DE "METHYLPHENYLTETRAHYDROPYRIDINE"

Results: 244

Acute Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) or Paraquat on Core Temperature in C57BL/6J Mice.

Published in:

Journal of Parkinson's Disease, 2015, v. 5, n. 2, p. 389, doi. 10.3233/JPD-140424

By:

Yun Jiao;
Yuchen Dou;
Lockwood, Georgina;
Pani, Amar;
Smeyne, Richard Jay

Publication type:

Article

Genetic Susceptibility Model of Parkinson's Disease Resulting from Exposure of DJ-1 Deficient Mice to MPTP: Evaluation of Neuroprotection by Ubisol-Q10.

Published in:

Journal of Parkinson's Disease, 2014, v. 4, n. 3, p. 523, doi. 10.3233/JPD-140368

By:

Muthukumaran, Krithika;
Smith, Jessica;
Jasra, Harshil;
Sikorska, Marianna;
Sandhu, Jagdeep K.;
Cohen, Jerome;
Lopatin, Daniel;
Pandey, Siyaram

Publication type:

Article

Near-infrared light (670 nm) reduces MPTP-induced parkinsonism within a broad therapeutic time window.

Published in:

Experimental Brain Research, 2016, v. 234, n. 7, p. 1787, doi. 10.1007/s00221-016-4578-8

By:

Reinhart, Florian;
El Massri, Nabil;
Johnstone, Daniel;
Stone, Jonathan;
Mitrofanis, John;
Benabid, Alim-Louis;
Moro, Cécile

Publication type:

Article

MPTP-treated mice: long-lasting loss of nigral TH-ir neurons but not paradoxical sleep alterations.

Published in:

Experimental Brain Research, 2008, v. 186, n. 4, p. 635, doi. 10.1007/s00221-008-1268-1

By:

Laloux, Charlotte;
Derambure, Philippe;
Kreisler, Alexandre;
Houdayer, Elise;
Bruezière, Servane;
Bordet, Régis;
Destée, Alain;
Monaca, Christelle

Publication type:

Article

β adrenergic receptor selective stimulation during ischemia/reperfusion improves cardiac function in translational models through inhibition of mPTP opening in cardiomyocytes.

Published in:

Basic Research in Cardiology, 2014, v. 109, n. 4, p. 1, doi. 10.1007/s00395-014-0422-0

By:

García-Prieto, Jaime;
García-Ruiz, Jose;
Sanz-Rosa, David;
Pun, Andrés;
García-Alvarez, Ana;
Davidson, Sean;
Fernández-Friera, Leticia;
Nuno-Ayala, Mario;
Fernández-Jiménez, Rodrigo;
Bernal, Juan;
Izquierdo-Garcia, José;
Jimenez-Borreguero, Jesús;
Pizarro, Gonzalo;
Ruiz-Cabello, Jesús;
Macaya, Carlos;
Fuster, Valentín;
Yellon, Derek;
Ibanez, Borja

Publication type:

Article

Matrix metalloproteinase inhibition protects CyPD knockout mice independently of RISK/mPTP signalling: a parallel pathway to protection.

Published in:

Basic Research in Cardiology, 2013, v. 108, n. 2, p. 1, doi. 10.1007/s00395-013-0331-7

By:

Bell, Robert;
Kunuthur, Suma;
Hendry, Cara;
Bruce-Hickman, Damian;
Davidson, Sean;
Yellon, Derek

Publication type:

Article

Taurine fails to protect against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced striatal dopamine depletion in mice.

Published in:

Amino Acids, 2008, v. 35, n. 2, p. 457, doi. 10.1007/s00726-007-0571-7

By:

A. K. Navneet;
T. A. Appukuttan;
M. Pandey;
K. P. Mohanakumar

Publication type:

Article

7,8-dihydroxyflavone ameliorates motor deficits via regulating autophagy in MPTP-induced mouse model of Parkinson's disease.

Published in:

Cell Death Discovery, 2021, v. 7, n. 1, p. 1, doi. 10.1038/s41420-021-00643-5

By:

Zuo, Li;
Dai, Chunfang;
Yi, Lilin;
Dong, Zhifang

Publication type:

Article

Neuroprotective effect of matrine on MPTP-induced Parkinson's disease and on Nrf2 expression.

Published in:

Oncology Letters, 2017, v. 13, n. 1, p. 296, doi. 10.3892/ol.2016.5383

By:

FANHUA MENG;
JIANHUI WANG;
FUXIANG DING;
YUNLIANG XIE;
YINGJIE ZHANG;
JIE ZHU

Publication type:

Article

Dopamine Receptor D3 Expression Is Altered in CD4+ T-Cells From Parkinson's Disease Patients and Its Pharmacologic Inhibition Attenuates the Motor Impairment in a Mouse Model.

Published in:

Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2019.00981

By:

Elgueta, Daniela;
Contreras, Francisco;
Prado, Carolina;
Montoya, Andro;
Ugalde, Valentina;
Chovar, Ornella;
Villagra, Roque;
Henríquez, Claudio;
Abellanas, Miguel A.;
Aymerich, María S.;
Franco, Rarael;
Pacheco, Rodrigo

Publication type:

Article

Chronic MPTP administration regimen in monkeys: a model of dopaminergic and non-dopaminergic cell loss in Parkinson’s disease.

Published in:

Journal of Neural Transmission, 2018, v. 125, n. 3, p. 337, doi. 10.1007/s00702-017-1774-z

By:

Masilamoni, Gunasingh J.;
Smith, Yoland

Publication type:

Article

Disruption of programmed masticatory movements in unilateral MPTP-treated monkeys as a model of jaw movement abnormality in Parkinson's disease.

Published in:

Journal of Neural Transmission, 2012, v. 119, n. 8, p. 933, doi. 10.1007/s00702-012-0768-0

By:

Adachi, Kazunori;
Kobayashi, Masayuki;
Kawasaki, Toshiyuki;
Yokoyama, Chihiro;
Waddington, John;
Sakagami, Hiroshi;
Onoe, Hirotaka;
Koshikawa, Noriaki

Publication type:

Article

Differential effects of dopamine melanin on norharman-induced toxicity in PC12 cells.

Published in:

Journal of Neural Transmission, 2007, v. 114, n. 7, p. 909, doi. 10.1007/s00702-006-0622-3

By:

Östergren, A.;
Lindquist, N. G.;
Brittebo, E. B.

Publication type:

Article

Changes in the neuronal activity in the pedunculopontine nucleus in chronic MPTP-treated primates: an in situ hybridization study of cytochrome oxidase subunit I, choline acetyl transferase and substance P mRNA expression.

Published in:

Journal of Neural Transmission, 2007, v. 114, n. 3, p. 319, doi. 10.1007/s00702-006-0547-x

By:

Gomez-Gallego, M.;
Fernandez-Villalba, E.;
Fernandez-Barreiro, A.;
Herrero, M. T.

Publication type:

Article

Time dependent alterations of co-localization of S100β and GFAP in the MPTP-treated mice.

Published in:

Journal of Neural Transmission, 2006, v. 113, n. 12, p. 1887, doi. 10.1007/s00702-006-0482-x

By:

Himeda, T.;
Watanabe, Y.;
Tounai, H.;
Hayakawa, N.;
Kato, H.;
Araki, T.

Publication type:

Article

Influence of noradrenaline denervation on MPTP-induced deficits in mice.

Published in:

Journal of Neural Transmission, 2006, v. 113, n. 9, p. 1119, doi. 10.1007/s00702-005-0402-5

By:

Archer, T.;
Fredriksson, A.

Publication type:

Article

Effects of riluzole on combined MPTP?+?3-nitropropionic acid-induced mild to moderate striatonigral degeneration in mice.

Published in:

Journal of Neural Transmission, 2005, v. 112, n. 5, p. 613, doi. 10.1007/s00702-004-0206-z

By:

Diguet, E.;
Fernagut, P.-O.;
Scherfler, C.;
Wenning, G.;
Tison, F.

Publication type:

Article

Attenuation of levodopa-induced dyskinesia by normalizing dopamine D3 receptor function.

Published in:

Nature Medicine, 2003, v. 9, n. 6, p. 762, doi. 10.1038/nm875

By:

Bezard, Erwan;
Ferry, Sandrine;
Mach, Ulrich;
Stark, Holger;
Leriche, Ludovic;
Boraud, Thomas;
Gross, Christian;
Sokoloff, Pierre

Publication type:

Article

Protection of Dopamine Neurons by Vibration Training and Up-Regulation of Brain-Derived Neurotrophic Factor in a MPTP Mouse Model of Parkinson's Disease.

Published in:

Physiological Research, 2014, v. 63, n. 5, p. 649, doi. 10.33549/physiolres.932743

By:

ZHAO, L.;
HE, L. X.;
HUANG, S. N.;
GONG, L. J.;
LI, L.;
LV, Y. Y.;
QIAN, Z. M.

Publication type:

Article

Is there neuroprotection in Parkinson syndrome?

Published in:

Journal of Neurology, 2000, v. 247, p. IV8, doi. 10.1007/PL00007777

By:

Riederer, P.;
Sian, J.;
Gerlach, M.

Publication type:

Article

Edaravone protects osteoblastic cells from dexamethasone through inhibiting oxidative stress and mPTP opening.

Published in:

Molecular & Cellular Biochemistry, 2015, v. 409, n. 1/2, p. 51, doi. 10.1007/s11010-015-2511-2

By:

Sun, Wen-xiao;
Zheng, Hai-ya;
Lan, Jun

Publication type:

Article

Reduced cholinergic olfactory centrifugal inputs in patients with neurodegenerative disorders and MPTP-treated monkeys.

Published in:

Acta Neuropathologica, 2013, v. 126, n. 3, p. 411, doi. 10.1007/s00401-013-1144-3

By:

Mundiñano, Iñaki-Carril;
Hernandez, Maria;
DiCaudo, Carla;
Ordoñez, Cristina;
Marcilla, Irene;
Tuñon, Maria-Teresa;
Luquin, Maria-Rosario

Publication type:

Article

The binding energy of nitrogen 1 s electrons in pyridine derivatives: Substituent effects in N-centered radical cations.

Published in:

High Energy Chemistry, 2009, v. 43, n. 6, p. 427, doi. 10.1134/S0018143909060010

By:

Khamaletdinova, N.;
Egorochkin, A.;
Kuznetsova, O.

Publication type:

Article

Involvement of brain dopaminergic systems in the development of an MPTP-induced depressive state in rats.

Published in:

Neuroscience & Behavioral Physiology, 2008, v. 38, n. 4, p. 383, doi. 10.1007/s11055-008-0055-6

By:

N. Pankova;
N. Krupina;
I. Orlova;
N. Khlebnikova;
G. Kryzhanovskii

Publication type:

Article

The Role of Iron in Parkinson Disease and 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Toxicity.

Published in:

IUBMB Life, 1999, v. 48, n. 2, p. 139, doi. 10.1080/152165499307134

By:

Yantiri, Ferda;
Andersen, Julie K.

Publication type:

Article

Necroptosis Interfaces with MOMP and the MPTP in Mediating Cell Death.

Published in:

PLoS ONE, 2015, v. 10, n. 6, p. 1, doi. 10.1371/journal.pone.0130520

By:

Karch, Jason;
Kanisicak, Onur;
Brody, Matthew J.;
Sargent, Michelle A.;
Michael, Demetria M.;
Molkentin, Jeffery D.

Publication type:

Article

Targeted Overexpression of α-Synuclein by rAAV2/1 Vectors Induces Progressive Nigrostriatal Degeneration and Increases Vulnerability to MPTP in Mouse.

Published in:

PLoS ONE, 2015, v. 10, n. 6, p. 1, doi. 10.1371/journal.pone.0131281

By:

Song, Lian-Kun;
Ma, Kai-Li;
Yuan, Yu-He;
Mu, Zheng;
Song, Xiu-Yun;
Niu, Fei;
Han, Ning;
Chen, Nai-Hong

Publication type:

Article

Small Peptide Inhibitor of JNK3 Protects Dopaminergic Neurons from MPTP Induced Injury via Inhibiting the ASK1-JNK3 Signaling Pathway.

Published in:

PLoS ONE, 2015, v. 10, n. 4, p. 1, doi. 10.1371/journal.pone.0119204

By:

Pan, Jing;
Li, Hui;
Zhang, Bei;
Xiong, Ran;
Zhang, Yu;
Kang, Wen-Yan;
Chen, Wei;
Zhao, Zong-Bo;
Chen, Sheng-Di

Publication type:

Article

Photo-Induction and Automated Quantification of Reversible Mitochondrial Permeability Transition Pore Opening in Primary Mouse Myotubes.

Published in:

PLoS ONE, 2014, v. 9, n. 11, p. 1, doi. 10.1371/journal.pone.0114090

By:

Blanchet, Lionel;
Grefte, Sander;
Smeitink, Jan A. M.;
Willems, Peter H. G. M.;
Koopman, Werner J. H.

Publication type:

Article

Attenuation of Skeletal Muscle and Renal Injury to the Lower Limb following Ischemia-Reperfusion Using mPTP Inhibitor NIM-811.

Published in:

PLoS ONE, 2014, v. 9, n. 6, p. 1, doi. 10.1371/journal.pone.0101067

By:

Garbaisz, David;
Turoczi, Zsolt;
Aranyi, Peter;
Fulop, Andras;
Rosero, Oliver;
Hermesz, Edit;
Ferencz, Agnes;
Lotz, Gabor;
Harsanyi, Laszlo;
Szijarto, Attila

Publication type:

Article

Alterations in Energy Metabolism, Neuroprotection and Visual Signal Transduction in the Retina of Parkinsonian, MPTP-Treated Monkeys.

Published in:

PLoS ONE, 2013, v. 8, n. 9, p. 1, doi. 10.1371/journal.pone.0074439

By:

Campello, Laura;
Esteve-Rudd, Julián;
Bru-Martínez, Roque;
Herrero, María Trinidad;
Fernández-Villalba, Emiliano;
Cuenca, Nicolás;
Martín-Nieto, José

Publication type:

Article

Adult Bone Marrow Neural Crest Stem Cells and Mesenchymal Stem Cells Are Not Able to Replace Lost Neurons in Acute MPTP-Lesioned Mice

Published in:

PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0064723

By:

Neirinckx, Virginie;
Marquet, Alice;
Coste, Cécile;
Rogister, Bernard;
Wislet-Gendebien, Sabine

Publication type:

Article

PET Analysis of Dopaminergic Neurodegeneration in Relation to Immobility in the MPTP-Treated Common Marmoset, a Model for Parkinson's Disease.

Published in:

PLoS ONE, 2012, v. 7, n. 10, p. 1, doi. 10.1371/journal.pone.0046371

By:

Ando, Kiyoshi;
Obayashi, Shigeru;
Nagai, Yuji;
Oh-Nishi, Arata;
Minamimoto, Takafumi;
Higuchi, Makoto;
Inoue, Takashi;
Itoh, Toshio;
Suhara, Tetsuya

Publication type:

Article

The Monoamine Re-Uptake Inhibitor UWA-101 Improves Motor Fluctuations in the MPTP-Lesioned Common Marmoset.

Published in:

PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0045587

By:

Huot, Philippe;
Johnston, Tom H.;
Gandy, Michael N.;
Reyes, M. Gabriela;
Fox, Susan H.;
Piggott, Matthew J.;
Brotchie, Jonathan M.;
Sgambato-Faure, Veronique

Publication type:

Article

Early Presymptomatic and Long-Term Changes of Rest Activity Cycles and Cognitive Behavior in a MPTP-Monkey Model of Parkinson's Disease.

Published in:

PLoS ONE, 2011, v. 6, n. 8, p. 1, doi. 10.1371/journal.pone.0023952

By:

Vezoli, Julien;
Fifel, Karim;
Leviel, Vincent;
Dehay, Colette;
Kennedy, Henry;
Cooper, Howard M.;
Gronfier, Claude;
Procyk, Emmanuel

Publication type:

Article

Resistance to MPTP-Neurotoxicity in α-Synuclein Knockout Mice Is Complemented by Human α-Synuclein and Associated with Increased β-Synuclein and Akt Activation.

Published in:

PLoS ONE, 2011, v. 6, n. 1, p. 1, doi. 10.1371/journal.pone.0016706

By:

Thomas, Bobby;
Mandir, Allen S.;
West, Neva;
Ying Liu;
Andrabi, Shaida A.;
Stirling, Wanda;
Dawson, Valina L.;
Dawson, Ted M.;
Lee, Michael K.

Publication type:

Article

Dopamine Transporter Binding Is Unaffected by L-DOPA Administration in Normal and MPTP-Treated Monkeys.

Published in:

PLoS ONE, 2010, v. 5, n. 11, p. 1, doi. 10.1371/journal.pone.0014053

By:

Fernagut, Pierre-Olivier;
Qin Li;
Dovero, Sandra;
Piu Chan;
Tao Wu;
Ravenscroft, Paula;
Hill, Michael;
Zhenwen Chen;
Bezard, Erwan

Publication type:

Article

Distinct Changes in cAMP and Extracellular Signal- Regulated Protein Kinase Signalling in L-DOPA-Induced Dyskinesia.

Published in:

PLoS ONE, 2010, v. 5, n. 8, p. 1, doi. 10.1371/journal.pone.0012321

By:

Gollner, Sabine;
Riemer, Barbara;
Arbizu, Pedro Martínez;
Bris, Nadine Le;
Bright, Monika

Publication type:

Article

Paradigm shifts in cardioprotection research: the importance of the MPTP as a therapeutic target.

Published in:

Cardiovascular Research, 2012, v. 96, n. 2, p. 160, doi. 10.1093/cvr/cvs174

By:

Hausenloy, Derek J.;
Maddock, Helen L.;
Baxter, Gary F.;
Yellon, Derek M.

Publication type:

Article

The mPTP and its regulatory proteins: final common targets of signalling pathways for protection against necrosis.

Published in:

Cardiovascular Research, 2012, v. 94, n. 2, p. 181, doi. 10.1093/cvr/cvr302

By:

Miura, Tetsuji;
Tanno, Masaya

Publication type:

Article

DEVELOPMENT OF AN HPLC METHOD FOR THE ANALYSIS OF 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE IN A POTENTIAL ANTIPSYCHOTICACTIVE PHARMACEUTICAL INGREDIENT.

Published in:

Journal of Liquid Chromatography & Related Technologies, 2000, v. 23, n. 16, p. 2553, doi. 10.1081/JLC-100100509

By:

Krikke, J.J.;
Karrick, G.L.;
Hagen, S.R.

Publication type:

Article

Enriched Environment Confers Resistance to 1-Methyl-4-Phenyl-1, 2,3,6-Tetrahydropyridine and Cocaine: Involvement of Dopamine Transporter and Trophic Factors.

Published in:

Journal of Neuroscience, 2003, v. 23, n. 35, p. 10999, doi. 10.1523/JNEUROSCI.23-35-10999.2003

By:

Bezard, Erwan;
Dovero, Sandra;
Belin, David;
Duconger, Sophie;
Jackson-Lewis, Vernice;
Przedborski, Serge;
Piazza, Pier Vincenzo;
Gross, Christian E.;
Jaber, Mohamed

Publication type:

Article

PYM50028, a novel, orally active, nonpeptide neurotrophic factor inducer, prevents and reverses neuronal damage induced by MPP+ in mesencephalic neurons and by MPTP in a mouse model of Parkinson's disease.

Published in:: FASEB Journal, 2008, v. 22, n. 7, p. 2488, doi. 10.1096/fj.07-095398
Publication type:: Article

MPTP-induced deficits in striatal synaptic plasticity are prevented by glial cell line-derived neurotrophic factor expressed via an adeno-associated viral vector.

Published in:

FASEB Journal, 2008, v. 22, n. 1, p. 261, doi. 10.1096/fj.07-8797com

By:

Yuan-Hao Chen;
Harvey, Brandon K.;
Hoffman, Alexander F.;
Yun Wang;
Yung-Hsiao Chiang;
Lupica, Carl R.

Publication type:

Article

Acute and subchronic MPTP administration differentially affect the serotonergic system in the striatum and prefrontal cortex.

Published in:

FASEB Journal, 2007, v. 21, n. 6, p. A1174, doi. 10.1096/fasebj.21.6.a1174-a

By:

Ansaht, Twum A.;
Ferguson, Marcus C.;
Nayyar, Tultul;
Deutch, Ariel Y.

Publication type:

Article

Developmental exposure to the pesticide dieldrin alters the dopamine system and increases neurotoxicity in an animal model of Parkinson's disease.

Published in:

FASEB Journal, 2006, v. 20, n. 10, p. 1695, doi. 10.1096/fj.06-5864fje

By:

Richardson, Jason R.;
Caudle, W. Michael;
Minzheng Wang;
Dean, E. Danielle;
Pennell, Kurt D.;
Miller, Gary W.

Publication type:

Article

Estrogen and neuroprotection: higher constitutive expression of glutaredoxin in female mice offers protection against MPTP-mediated neurodegeneration.

Published in:

FASEB Journal, 2004, v. 18, n. 10, p. 1102, doi. 10.1096/fj.03-1075fje

By:

Kenchappa, Rajappa S.;
Diwakar, Latha;
Annepu, Jayasree;
Ravindranath, Vijayalakshmi

Publication type:

Article

Low dose pramipexole is neuroprotective in the MPTP mouse model of Parkinson's disease, and downregulates the dopamine transporter via the D3 receptor.

Published in:

BMC Biology, 2004, v. 2, p. 1, doi. 10.1186/1741-7007-2-22

By:

Joyce, Jeffrey N.;
Woolsey, Cheryl;
Han Ryoo;
Borwege, Sabine;
Hagner, Diane

Publication type:

Article

Space Charge and Carrier Trapping Effects on the Transient Photocurrents of Organic Materials Using the Time-of-Flight Technique.

Published in:

Journal of Electronic Materials, 2008, v. 37, n. 3, p. 231, doi. 10.1007/s11664-007-0349-4

By:

Cusumano, P.;
Gambino, S.

Publication type:

Article

Synthesis and Characterization of Highly Soluble and Heat Stable New Poly(amide-ether)s Containing Pyridine Rings in the Main Chain.

Published in:

e-Polymers, 2008, p. 1

By:

Banihashemi, Ahmad;
Vakili, Mohammad Reza

Publication type:

Article