Works matching DE "METHYLPHENYLTETRAHYDROPYRIDINE"
Results: 241
PROTECTIVE EFFECT OF CENTELLA ASIATICA EXTRACT ON 1-METHYL-4-PHENYL 1,2,3,6 TETRAHYDROPYRIDINE (MPTP) INDUCED NEUROTOXICITY IN RATS.
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- Malaysian Journal of Medical Sciences, 2007, v. 14, p. 208
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- Article
MPTP-treated mice: long-lasting loss of nigral TH-ir neurons but not paradoxical sleep alterations.
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- Experimental Brain Research, 2008, v. 186, n. 4, p. 635, doi. 10.1007/s00221-008-1268-1
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Synthesis and antimicrobial properties of 2-chloro(bromo, thiocyanato)-1-aryl-2-methyl-3-chloropropanes.
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- Pharmaceutical Chemistry Journal, 2008, v. 42, n. 9, p. 520, doi. 10.1007/s11094-009-0169-3
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- Article
Oral administration of coenzyme Q reduces MPTP-induced loss of dopaminergic nerve terminals in the striatum in mice.
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- Neurological Sciences, 2012, v. 33, n. 1, p. 195, doi. 10.1007/s10072-011-0627-z
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- Article
Photobiomodulation Mitigates Cerebrovascular Leakage Induced by the Parkinsonian Neurotoxin MPTP.
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- Biomolecules (2218-273X), 2019, v. 9, n. 10, p. 564, doi. 10.3390/biom9100564
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Viscero-cortical interaction during sleep in MPTP treated monkeys.
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- 2000
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- Abstract
Nullification of a positive correlation between urinary contents of α[sub 1] -microglobulin and ulinastatin with intracerebroventricularly administered 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and 1-methyl-4-phenylpyridinium (MPP[s...
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- Psychopharmacology, 1998, v. 136, n. 4, p. 374, doi. 10.1007/s002130050580
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- Article
Normalization of markers for dopamine innervation in striatum of MPTP-lesioned miniature pigs with intrastriatal grafts.
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- Acta Neurologica Scandinavica, 2001, v. 103, n. 5, p. 309, doi. 10.1034/j.1600-0404.2001.103005309.x
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Characterisation of behavioural and neurodegenerative changes induced by intranigral 6-hydroxydopamine lesions in a mouse model of Parkinson’s disease.
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- European Journal of Neuroscience, 2010, v. 31, n. 12, p. 2266, doi. 10.1111/j.1460-9568.2010.07265.x
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- Article
Transgenic expression and activation of PGC-1α protect dopaminergic neurons in the MPTP mouse model of Parkinson's disease.
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- Cellular & Molecular Life Sciences, 2012, v. 69, n. 7, p. 1153, doi. 10.1007/s00018-011-0850-z
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Selective VIP Receptor Agonists Facilitate Immune Transformation for Dopaminergic Neuroprotection in MPTP-Intoxicated Mice.
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- Journal of Neuroscience, 2015, v. 35, n. 50, p. 16463, doi. 10.1523/JNEUROSCI.2131-15.2015
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Modulations in Oscillatory Frequency and Coupling in Globus Pallidus with Increasing Parkinsonian Severity.
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- Journal of Neuroscience, 2015, v. 35, n. 15, p. 6231, doi. 10.1523/JNEUROSCI.4137-14.2015
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- Article
PYM50028, a novel, orally active, nonpeptide neurotrophic factor inducer, prevents and reverses neuronal damage induced by MPP<sup>+</sup> in mesencephalic neurons and by MPTP in a mouse model of Parkinson's disease.
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- FASEB Journal, 2008, v. 22, n. 7, p. 2488, doi. 10.1096/fj.07-095398
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- Article
MPTP-induced deficits in striatal synaptic plasticity are prevented by glial cell line-derived neurotrophic factor expressed via an adeno-associated viral vector.
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- FASEB Journal, 2008, v. 22, n. 1, p. 261, doi. 10.1096/fj.07-8797com
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Acute and subchronic MPTP administration differentially affect the serotonergic system in the striatum and prefrontal cortex.
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- FASEB Journal, 2007, v. 21, n. 6, p. A1174, doi. 10.1096/fasebj.21.6.a1174-a
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Developmental exposure to the pesticide dieldrin alters the dopamine system and increases neurotoxicity in an animal model of Parkinson's disease.
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- FASEB Journal, 2006, v. 20, n. 10, p. 1695, doi. 10.1096/fj.06-5864fje
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Estrogen and neuroprotection: higher constitutive expression of glutaredoxin in female mice offers protection against MPTP-mediated neurodegeneration.
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- FASEB Journal, 2004, v. 18, n. 10, p. 1102, doi. 10.1096/fj.03-1075fje
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Attenuation of MPTP-induced neurotoxicity and locomotor dysfunction in Nucling-deficient mice via suppression of the apoptosome pathway.
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- Journal of Neurochemistry, 2006, v. 97, n. 4, p. 1126, doi. 10.1111/j.1471-4159.2006.03833.x
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- Article
Pramipexole protects against MPTP toxicity in non-human primates.
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- Journal of Neurochemistry, 2006, v. 96, n. 5, p. 1315, doi. 10.1111/j.1471-4159.2005.03625.x
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- Article
Novel multifunctional neuroprotective iron chelator-monoamine oxidase inhibitor drugs for neurodegenerative diseases. In vivo selective brain monoamine oxidase inhibition and prevention of MPTP-induced striatal dopamine depletion.
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- Journal of Neurochemistry, 2005, v. 95, n. 1, p. 79, doi. 10.1111/j.1471-4159.2005.03341.x
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- Article
Developmental loss and resistance to MPTP toxicity of dopaminergic neurones in substantia nigra pars compacta of γ-synuclein, α-synuclein and double α/γ-synuclein null mutant mice.
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- Journal of Neurochemistry, 2004, v. 89, n. 5, p. 1126, doi. 10.1111/j.1471-4159.2004.02378.x
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- Article
Attenuation of MPTP-induced dopaminergic neurotoxicity by TV3326, a cholinesterase-monoamine oxidase inhibitor.
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- Journal of Neurochemistry, 2003, v. 86, n. 2, p. 290, doi. 10.1046/j.1471-4159.2003.01801.x
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- Article
1-Methyl-4-phenylpridinium (MPP[sup +] )-induced functional run-down of GABA[sub A] receptor-mediated currents in acutely dissociated dopaminergic neurons.
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- Journal of Neurochemistry, 2002, v. 83, n. 1, p. 87, doi. 10.1046/j.1471-4159.2002.01099.x
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- Article
Increased vulnerability of dopaminergic neurons in MPTP-lesioned interleukin-6 deficient mice.
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- Journal of Neurochemistry, 2002, v. 83, n. 1, p. 167, doi. 10.1046/j.1471-4159.2002.01131.x
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- Article
A novel in vivo post-translational modification of p53 by PARP-1 in MPTP-induced parkinsonism.
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- Journal of Neurochemistry, 2002, v. 83, n. 1, p. 186, doi. 10.1046/j.1471-4159.2002.01144.x
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1-Methyl-4-phenylpyridinium ion, a toxin that can cause parkinsonism, alters branched structures of DNA.
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- Journal of Neurochemistry, 2002, v. 82, n. 1, p. 30, doi. 10.1046/j.1471-4159.2002.00996.x
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Protection from MPTP-induced neurotoxicity in differentiating mouse N2a neuroblastoma cells.
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- Journal of Neurochemistry, 2001, v. 76, n. 3, p. 650, doi. 10.1046/j.1471-4159.2001.00066.x
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Oxidative post-translational modifications of α-synuclein in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model of Parkinson's disease.
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- Journal of Neurochemistry, 2001, v. 76, n. 2, p. 637, doi. 10.1046/j.1471-4159.2001.00174.x
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Group II metabotropic glutamate receptor activation protects striatal dopaminergic nerve terminals against MPP[sup +]-induced neurotoxicity along with brain-derived neurotrophic factor induction.
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- Journal of Neurochemistry, 2001, v. 76, n. 2, p. 351, doi. 10.1046/j.1471-4159.2001.00056.x
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MPTP Activates c-Jun NH<sub>2</sub>-Terminal Kinase (JNK) and Its Upstream Regulatory Kinase MKK4 in Nigrostriatal Neurons In Vivo.
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- Journal of Neurochemistry, 2000, v. 75, n. 3, p. 1200, doi. 10.1046/j.1471-4159.2000.0751200.x
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METALLOTHIONEIN(MT) ISOFORMS PROTECT AGAINST MPTP-INDUCED PARKINSONISM.
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- 2000
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- Abstract
LLDT-67 attenuates MPTP-induced neurotoxicity in mice by up-regulating NGF expression.
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- Acta Pharmacologica Sinica, 2012, v. 33, n. 9, p. 1187, doi. 10.1038/aps.2012.88
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The ability of Alphitobius diaperinus homogenates immobilized on plant sorbent to block the development of mouse parkinsonism.
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- Doklady Biochemistry & Biophysics, 2015, v. 461, n. 1, p. 94, doi. 10.1134/S1607672915020088
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A low-dose chronic MPTP-model in the cat: First quantitative results on motor behaviour.
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- 2000
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- Abstract
Protective Effect of a New Monophenolic Antioxidant TS-13 in a Mouse Model of Parkinson's Disease.
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- Bulletin of Experimental Biology & Medicine, 2023, v. 175, n. 2, p. 265, doi. 10.1007/s10517-023-05847-6
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Chalcogenozidovudine Derivatives With Antitumor Activity: Comparative Toxicities in Cultured Human Mononuclear Cells.
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- Toxicological Sciences, 2017, v. 160, n. 1, p. 30, doi. 10.1093/toxsci/kfx152
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- Article
Vesicular Monoamine Transporter 2 (VMAT2) Level Regulates MPTP Vulnerability and Clearance of Excess Dopamine in Mouse Striatal Terminals.
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- Toxicological Sciences, 2016, v. 153, n. 1, p. 79, doi. 10.1093/toxsci/kfw106
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- Article
Novel Para-Phenyl Substituted Diindolylmethanes Protect Against MPTP Neurotoxicity and Suppress Glial Activation in a Mouse Model of Parkinson’s Disease.
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- Toxicological Sciences, 2015, v. 143, n. 2, p. 360, doi. 10.1093/toxsci/kfu236
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GM1 Oligosaccharide Efficacy in Parkinson's Disease: Protection against MPTP.
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- Biomedicines, 2023, v. 11, n. 5, p. 1305, doi. 10.3390/biomedicines11051305
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Synuclein Proteins in MPTP-Induced Death of Substantia Nigra Pars Compacta Dopaminergic Neurons.
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- Biomedicines, 2022, v. 10, n. 9, p. 2278, doi. 10.3390/biomedicines10092278
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Neurobehavioral protection by single dose l-deprenyl against MPTP-induced parkinsonism in common marmosets.
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- Psychopharmacology, 2008, v. 195, n. 4, p. 509, doi. 10.1007/s00213-007-0929-2
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Sub-chronic administration of the dopamine D[sub 1] antagonist SKF 83959 in bilaterally MPTP-treated rhesus monkeys: stable therapeutic effects and wearing-off dyskinesia.
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- Psychopharmacology, 1999, v. 146, n. 3, p. 328, doi. 10.1007/s002130051124
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Inhibition of platelet aggregation by 1-methyl-4-phenyl pyridinium ion (MPP+) through ATP depletion: Evidence for the reduced platelet activities in Parkinson's disease.
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- Platelets, 2009, v. 20, n. 3, p. 163, doi. 10.1080/09537100902721746
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Decrease of gene expression of astrocytic 5-HT<sub>2B</sub> receptors parallels development of depressive phenotype in a mouse model of Parkinson's disease.
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- Frontiers in Cellular Neuroscience, 2015, v. 9, p. 1, doi. 10.3389/fncel.2015.00388
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<italic>Lycium barbarum</italic> Polysaccharide Promotes Nigrostriatal Dopamine Function by Modulating PTEN/AKT/mTOR Pathway in a Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) Murine Model of Parkinson’s Disease.
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- Neurochemical Research, 2018, v. 43, n. 4, p. 938, doi. 10.1007/s11064-018-2499-6
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- Article
Toll Like Receptor 4 Affects the Cerebral Biochemical Changes Induced by MPTP Treatment.
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- Neurochemical Research, 2017, v. 42, n. 2, p. 493, doi. 10.1007/s11064-016-2095-6
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Blocking mPTP on Neural Stem Cells and Activating the Nicotinic Acetylcholine Receptor α7 Subunit on Microglia Attenuate Aβ-Induced Neurotoxicity on Neural Stem Cells.
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- Neurochemical Research, 2016, v. 41, n. 6, p. 1483, doi. 10.1007/s11064-016-1862-8
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Absence of Glia Maturation Factor Protects Dopaminergic Neurons and Improves Motor Behavior in Mouse Model of Parkinsonism.
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- Neurochemical Research, 2015, v. 40, n. 5, p. 980, doi. 10.1007/s11064-015-1553-x
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- Article
SIRT3 Attenuates MPTP-Induced Nigrostriatal Degeneration Via Enhancing Mitochondrial Antioxidant Capacity.
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- Neurochemical Research, 2015, v. 40, n. 3, p. 600, doi. 10.1007/s11064-014-1507-8
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- Article
The TrkB-Positive Dopaminergic Neurons are Less Sensitive to MPTP Insult in the Substantia Nigra of Adult C57/BL Mice.
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- Neurochemical Research, 2011, v. 36, n. 10, p. 1759, doi. 10.1007/s11064-011-0491-5
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- Article