Works matching DE "METHYLGUANINE"


Results: 774
    1

    Expanding clinicopathologic knowledge in high-grade glioma with pleomorphic and pseudopapillary features (HPAP): a report of two cases.

    Published in:
    2025
    By:
    • Rossi, Sabrina;
    • Giovannoni, Isabella;
    • Patrizi, Sara;
    • Mafficcini, Andrea;
    • Piccirilli, Eleonora;
    • Ricciardi, Giuseppe Kenneth;
    • Megaro, Giacomina;
    • Arienzo, Francesca;
    • Tancredi, Chantal;
    • Agolini, Emanuele;
    • Carai, Andrea;
    • Mastronuzzi, Angela;
    • Giannini, Caterina;
    • Locatelli, Franco;
    • Alaggio, Rita;
    • Colafati, Giovanna Stefania;
    • Alesi, Viola;
    • Miele, Evelina;
    • Barresi, Valeria
    Publication type:
    Case Study
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    O <sup>6</sup>-methylguanine DNA methyltransferase (MGMT) expression in U1242 glioblastoma cells enhances in vitro clonogenicity, tumor implantation in vivo , and sensitivity to alisertib-carboplatin combination treatment.

    Published in:
    Frontiers in Cellular Neuroscience, 2025, p. 1, doi. 10.3389/fncel.2025.1552015
    By:
    • Sak, Müge;
    • Williams, Brian J.;
    • Hey, Andrew J.;
    • Sharma, Mayur;
    • Schier, Leslie;
    • Wilson, Megan J.;
    • Ortega, Mahatma;
    • Lara, Alyssa I.;
    • Brentlinger, Mikaela N.;
    • Lehman, Norman L.
    Publication type:
    Article
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    Succinate mediates inflammation-induced adrenocortical dysfunction.

    Published in:
    eLife, 2023, p. 1, doi. 10.7554/eLife.83064
    By:
    • Mateska, Ivona;
    • Witt, Anke;
    • Hagag, Eman;
    • Sinha, Anupam;
    • Yilmaz, Canelif;
    • Thanou, Evangelia;
    • Sun, Na;
    • Kolliniati, Ourania;
    • Patschin, Maria;
    • Abdelmegeed, Heba;
    • Henneicke, Holger;
    • Kanczkowski, Waldemar;
    • Wielockx, Ben;
    • Tsatsanis, Christos;
    • Dahl, Andreas;
    • Walch, Axel Karl;
    • Ka Wan Li;
    • Peitzsch, Mirko;
    • Chavakis, Triantafyllos;
    • Alexaki, Vasileia Ismini
    Publication type:
    Article
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    Prolonged culturing of colonic epithelial organoids derived from healthy individuals and ulcerative colitis patients results in the decrease of LINE-1 methylation level.

    Published in:
    Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-55076-8
    By:
    • Inciuraite, Ruta;
    • Steponaitiene, Ruta;
    • Raudze, Odeta;
    • Kulokiene, Ugne;
    • Kiudelis, Vytautas;
    • Lukosevicius, Rokas;
    • Ugenskiene, Rasa;
    • Adamonis, Kestutis;
    • Kiudelis, Gediminas;
    • Jonaitis, Laimas Virginijus;
    • Kupcinskas, Juozas;
    • Skieceviciene, Jurgita
    Publication type:
    Article
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    Trans-lesion synthesis and mismatch repair pathway crosstalk defines chemoresistance and hypermutation mechanisms in glioblastoma.

    Published in:
    Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-45979-5
    By:
    • Cheng, Xing;
    • An, Jing;
    • Lou, Jitong;
    • Gu, Qisheng;
    • Ding, Weimin;
    • Droby, Gaith Nabil;
    • Wang, Yilin;
    • Wang, Chenghao;
    • Gao, Yanzhe;
    • Anand, Jay Ramanlal;
    • Shelton, Abigail;
    • Satterlee, Andrew Benson;
    • Mann, Breanna;
    • Hsiao, Yun-Chung;
    • Liu, Chih-Wei;
    • Lu, Kun;
    • Hingtgen, Shawn;
    • Wang, Jiguang;
    • Liu, Zhaoliang;
    • Miller, C. Ryan
    Publication type:
    Article
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    Detection of diagnostic and prognostic methylation-based signatures in liquid biopsy specimens from patients with meningiomas.

    Published in:
    Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-41434-z
    By:
    • Herrgott, Grayson A.;
    • Snyder, James M.;
    • She, Ruicong;
    • Malta, Tathiane M.;
    • Sabedot, Thais S.;
    • Lee, Ian Y.;
    • Pawloski, Jacob;
    • Podolsky-Gondim, Guilherme G.;
    • Asmaro, Karam P.;
    • Zhang, Jiaqi;
    • Cannella, Cara E.;
    • Nelson, Kevin;
    • Thomas, Bartow;
    • deCarvalho, Ana C.;
    • Hasselbach, Laura A.;
    • Tundo, Kelly M.;
    • Newaz, Rehnuma;
    • Transou, Andrea;
    • Morosini, Natalia;
    • Francisco, Victor
    Publication type:
    Article
    25

    A qPCR technology for direct quantification of methylation in untreated DNA.

    Published in:
    Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-40873-y
    By:
    • Bendixen, Kamilla Kolding;
    • Mindegaard, Maria;
    • Epistolio, Samantha;
    • Dazio, Giulia;
    • Marchi, Francesco;
    • Spina, Paolo;
    • Arnspang, Eva C.;
    • Soerensen, Mette;
    • Christensen, Ulf Bech;
    • Frattini, Milo;
    • Petersen, Rasmus Koefoed
    Publication type:
    Article
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    macroH2A2 antagonizes epigenetic programs of stemness in glioblastoma.

    Published in:
    Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-38919-2
    By:
    • Nikolic, Ana;
    • Maule, Francesca;
    • Bobyn, Anna;
    • Ellestad, Katrina;
    • Paik, Seungil;
    • Marhon, Sajid A.;
    • Mehdipour, Parinaz;
    • Lun, Xueqing;
    • Chen, Huey-Miin;
    • Mallard, Claire;
    • Hay, Alexander J.;
    • Johnston, Michael J.;
    • Gafuik, Christopher J.;
    • Zemp, Franz J.;
    • Shen, Yaoqing;
    • Ninkovic, Nicoletta;
    • Osz, Katalin;
    • Labit, Elodie;
    • Berger, N. Daniel;
    • Brownsey, Duncan K.
    Publication type:
    Article
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    Loss of SPINT2 expression frequently occurs in glioma, leading to increased growth and invasion via MMP2.

    Published in:
    Cellular Oncology (2211-3428), 2020, v. 43, n. 1, p. 107, doi. 10.1007/s13402-019-00475-7
    By:
    • Pereira, Márcia Santos;
    • Celeiro, Sónia Pires;
    • Costa, Ângela Margarida;
    • Pinto, Filipe;
    • Popov, Sergey;
    • de Almeida, Gisele Caravina;
    • Amorim, Júlia;
    • Pires, Manuel Melo;
    • Pinheiro, Célia;
    • Lopes, José Manuel;
    • Honavar, Mrinalini;
    • Costa, Paulo;
    • Pimentel, José;
    • Jones, Chris;
    • Reis, Rui Manuel;
    • Viana-Pereira, Marta
    Publication type:
    Article
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    The novel SMYD3 inhibitor EM127 impairs DNA repair response to chemotherapy-induced DNA damage and reverses cancer chemoresistance.

    Published in:
    Journal of Experimental & Clinical Cancer Research (17569966), 2024, v. 43, p. 1, doi. 10.1186/s13046-024-03078-9
    By:
    • Sanese, Paola;
    • De Marco, Katia;
    • Lepore Signorile, Martina;
    • La Rocca, Francesca;
    • Forte, Giovanna;
    • Latrofa, Marialaura;
    • Fasano, Candida;
    • Disciglio, Vittoria;
    • Di Nicola, Elisabetta;
    • Pantaleo, Antonino;
    • Bianco, Giusy;
    • Spilotro, Vito;
    • Ferroni, Claudia;
    • Tubertini, Matilde;
    • Labarile, Nicoletta;
    • De Marinis, Lucia;
    • Armentano, Raffaele;
    • Gigante, Gianluigi;
    • Lantone, Valerio;
    • Lantone, Giuliano
    Publication type:
    Article
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    Molecular landscape of IDH‐wild type, pTERT‐wild type adult glioblastomas.

    Published in:
    Brain Pathology, 2022, v. 32, n. 6, p. 1, doi. 10.1111/bpa.13107
    By:
    • Liu, Emma Munan;
    • Shi, Zhi‐Feng;
    • Li, Kay Ka‐Wai;
    • Malta, Tathiane M.;
    • Chung, Nellie Yuk‐Fei;
    • Chen, Hong;
    • Chan, Janice Yuen‐Tung;
    • Poon, Manix Fung‐Man;
    • Kwan, Johnny Sheung‐Him;
    • Chan, Danny Tat‐Ming;
    • Noushmehr, Houtan;
    • Mao, Ying;
    • Ng, Ho‐Keung
    Publication type:
    Article
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