Works matching DE "METHYLCYTOSINE"

Results: 467

RNA m5C modification: from physiology to pathology and its biological significance.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1599305

By:

Chen, Xi;
Yuan, Yixiao;
Zhou, Fan;
Huang, Xiaobing;
Li, Lihua;
Pu, Jun;
Zeng, Yong;
Jiang, Xiulin

Publication type:

Article

Existence of differential epigenetic control in a pair of cultivated tobacco (Nicotiana tabacum L.) cultivars harbouring contrast nicotine levels.

Published in:

Indian Journal of Biochemistry & Biophysics, 2025, v. 62, n. 5, p. 457, doi. 10.56042/ijbb.v62i5.1717

By:

Manoharlal, Raman;
Saiprasad, G. V. S.

Publication type:

Article

Changes in genomic 5-methylcytosine level mirror the response of orthodox (Acer platanoides L.) and recalcitrant (Acer pseudoplatanus L.) seeds to severe desiccation.

Published in:

Tree Physiology, 2018, v. 38, n. 4, p. 617, doi. 10.1093/treephys/tpx134

By:

Plitta-Michalak, Beata P;
Naskręt-Barciszewska, Mirosława Z;
Kotlarski, Szymon;
Tomaszewski, Dominik;
Tylkowski, Tadeusz;
Barciszewski, Jan;
Chmielarz, Paweł;
Michalak, Marcin

Publication type:

Article

Quantification of cytosine modifications in the aged mouse brain.

Published in:

Neuropsychopharmacology Reports, 2024, v. 44, n. 1, p. 250, doi. 10.1002/npr2.12396

By:

Sugawara, Hiroko;
Date, Akitoshi;
Fuke, Satoshi;
Nakachi, Yutaka;
Kato, Tadafumi;
Narita, Minoru;
Bundo, Miki;
Iwamoto, Kazuya

Publication type:

Article

Studying epigenetic DNA modifications in undergraduate laboratories using complementary bioinformatic and molecular approaches.

Published in:

Biochemistry & Molecular Biology Education, 2013, v. 41, n. 5, p. 334, doi. 10.1002/bmb.20713

By:

Militello, Kevin T.

Publication type:

Article

Coevolution of the CDCA7-HELLS ICF-related nucleosome remodeling complex and DNA methyltransferases.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.86721

By:

Hironori Funabiki;
Wassing, Isabel E.;
Qingyuan Jia;
Ji-Dung Luo;
Carroll, Thomas

Publication type:

Article

Multi-omic analyses of m5C readers reveal their characteristics and immunotherapeutic proficiency.

Published in:

Scientific Reports, 2024, v. 13, n. 1, p. 1, doi. 10.1038/s41598-024-52110-7

By:

Xu, Rui;
Wang, Yue;
Kuang, Ye

Publication type:

Article

Whole‑exome sequencing reveals Lewis lung carcinoma is a hypermutated Kras/Nras–mutant cancer with extensive regional mutation clusters in its genome.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-023-50703-2

By:

He, Quan;
Sun, Cuirong;
Pan, Yuanjiang

Publication type:

Article

Identification and validation of novel prognostic signatures based on m5C methylation patterns and tumor EMT profiles in head and neck squamous cell carcinoma.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-45976-6

By:

Zhu, Guanghao;
Wang, Wei;
Yao, Hui;
Li, Haopu;
Zhang, Caiyun;
Meng, Yindi;
Wang, Jingjie;
Zhu, Minhui;
Zheng, Hongliang

Publication type:

Article

Embryonic abnormalities and genotoxicity induced by 2,4-dichlorophenoxyacetic acid during indirect somatic embryogenesis in Coffea.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-36879-7

By:

de Morais Oliveira, João Paulo;
Silva, Alex Junior da;
Catrinck, Mariana Neves;
Clarindo, Wellington Ronildo

Publication type:

Article

Immunohistochemical loss of 5-hydroxymethylcytosine expression in acute myeloid leukaemia: relationship to somatic gene mutations affecting epigenetic pathways.

Published in:

Histopathology, 2016, v. 69, n. 6, p. 1055, doi. 10.1111/his.13046

By:

Magotra, Minoti;
Sakhdari, Ali;
Lee, Paul J;
Tomaszewicz, Keith;
Dresser, Karen;
Hutchinson, Lloyd M;
Woda, Bruce A;
Chen, Benjamin J

Publication type:

Article

Characterization of BisI Homologs.

Published in:

Frontiers in Microbiology, 2021, v. 12, p. 1, doi. 10.3389/fmicb.2021.689929

By:

Xu, Shuang-yong;
Zemlyanskaya, Elena V.;
Gonchar, Danila A.;
Sun, Zhiyi;
Weigele, Peter;
Fomenkov, Alexey;
Degtyarev, Sergey Kh;
Roberts, Richard J.

Publication type:

Article

5mC modification orchestrates choriogenesis and fertilization by preventing prolonged ftz-f1 expression.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-43987-5

By:

Zhao, Zheng;
Li, Liang;
Zeng, Ruichen;
Lin, Liangguan;
Yuan, Dongwei;
Wen, Yejie;
Li, Na;
Cui, Yingying;
Zhu, Shiming;
Zhang, Zhi-Min;
Li, Sheng;
Ren, Chonghua

Publication type:

Article

Brain methylome remodeling selectively regulates neuronal activity genes linking to emotional behaviors in mice exposed to maternal immune activation.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-43497-4

By:

Ma, Li;
Wang, Feng;
Li, Yangping;
Wang, Jing;
Chang, Qing;
Du, Yuanning;
Sadan, Jotham;
Zhao, Zhen;
Fan, Guoping;
Yao, Bing;
Chen, Jian-Fu

Publication type:

Article

DNA 5-methylcytosine detection and methylation phasing using PacBio circular consensus sequencing.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-39784-9

By:

Ni, Peng;
Nie, Fan;
Zhong, Zeyu;
Xu, Jinrui;
Huang, Neng;
Zhang, Jun;
Zhao, Haochen;
Zou, You;
Huang, Yuanfeng;
Li, Jinchen;
Xiao, Chuan-Le;
Luo, Feng;
Wang, Jianxin

Publication type:

Article

High-throughput sequencing offers new insights into 5-hydroxymethylcytosine.

Published in:

Biomolecular Concepts, 2016, v. 7, n. 3, p. 169, doi. 10.1515/bmc-2016-0011

By:

Pang, Alina P.S.;
Sugai, Christopher;
Maunakea, Alika K.

Publication type:

Article

Tet proteins: on track towards DNA demethylation?

Published in:

Biomolecular Concepts, 2012, v. 3, n. 5, p. 395, doi. 10.1515/bmc-2012-0022

By:

Véron, Nathalie

Publication type:

Article

Mitochondrial DNA: a blind spot in neuroepigenetics.

Published in:

Biomolecular Concepts, 2012, v. 3, n. 2, p. 107, doi. 10.1515/bmc-2011-0058

By:

Manev, Hari;
Dzitoyeva, Svetlana;
Chen, Hu

Publication type:

Article

Differential genome-wide DNA methylation patterns in childhood obesity.

Published in:

BMC Research Notes, 2019, v. 12, n. 1, p. N.PAG, doi. 10.1186/s13104-019-4189-0

By:

Cao-Lei, Lei;
Elgbeili, Guillaume;
Szyf, Moshe;
Laplante, David P.;
King, Suzanne

Publication type:

Article

Inhibition of cytosine 5-hydroxymethylation during progression of cancer precursor lesions in the uterine cervix.

Published in:

PLoS ONE, 2024, v. 19, n. 4, p. 1, doi. 10.1371/journal.pone.0297008

By:

Moshi, Jobran M.;
Ummelen, Monique;
Smedts, Frank;
Ramaekers, Frans C. S.;
Hopman, Anton H. N.

Publication type:

Article

Tet-dependent 5-hydroxymethyl-Cytosine modification of mRNA regulates axon guidance genes in Drosophila.

Published in:

PLoS ONE, 2024, v. 19, n. 2, p. 1, doi. 10.1371/journal.pone.0293894

By:

Singh, Badri Nath;
Tran, Hiep;
Kramer, Joseph;
Kirichenko, Elmira;
Changela, Neha;
Wang, Fei;
Feng, Yaping;
Kumar, Dibyendu;
Tu, Min;
Lan, Jie;
Bizet, Martin;
Fuks, François;
Steward, Ruth

Publication type:

Article

Synonymous alterations of cancer-associated Trp53 CpG mutational hotspots cause fatal developmental jaw malocclusions but no tumors in knock-in mice.

Published in:

PLoS ONE, 2023, v. 18, n. 4, p. 1, doi. 10.1371/journal.pone.0284327

By:

Epstein, Richard J.;
Lin, Frank P. Y.;
Brink, Robert A.;
Blackburn, James

Publication type:

Article

The emerging role of DNA methylation in epileptogenesis.

Published in:

Epilepsia (Series 4), 2012, v. 53, p. 11, doi. 10.1111/epi.12031

By:

Kobow, Katja;
Blümcke, Ingmar

Publication type:

Article

The upregulation of NLRP3 inflammasome in dorsal root ganglion by ten-eleven translocation methylcytosine dioxygenase 2 (TET2) contributed to diabetic neuropathic pain in mice.

Published in:

Journal of Neuroinflammation, 2022, v. 19, n. 1, p. 1, doi. 10.1186/s12974-022-02669-7

By:

Chen, Wen;
Wang, Xiaotong;
Sun, Qingyu;
Zhang, Yurui;
Liu, Jing;
Hu, Tingting;
Wu, Weihua;
Wei, Chao;
Liu, Meng;
Ding, Yumeng;
Liu, Dianxin;
Chong, Yingzi;
Wang, Peipei;
Zhu, Hongwei;
Cui, Weihua;
Zhang, Jiannan;
Li, Qian;
Yang, Fei

Publication type:

Article

Emerging links between iron-sulfur clusters and 5-methylcytosine base excision repair in plants.

Published in:

Genes & Genetic Systems, 2016, v. 91, n. 2, p. 51, doi. 10.1266/ggs.16-00015

By:

Buzas, Diana Mihaela

Publication type:

Article

Base-resolution maps of 5-formylcytosine and 5-carboxylcytosine reveal genome-wide DNA demethylation dynamics.

Published in:

Cell Research, 2015, v. 25, n. 3, p. 386, doi. 10.1038/cr.2015.5

By:

Lu, Xingyu;
Han, Dali;
Zhao, Boxuan Simen;
Song, Chun-Xiao;
Zhang, Li-Sheng;
Doré, Louis C;
He, Chuan

Publication type:

Article

Crystal structures of isoorotate decarboxylases reveal a novel catalytic mechanism of 5-carboxyl-uracil decarboxylation and shed light on the search for DNA decarboxylase.

Published in:

Cell Research, 2013, v. 23, n. 11, p. 1296, doi. 10.1038/cr.2013.107

By:

Xu, Shutong;
Li, Wenjing;
Zhu, Junjun;
Wang, Rong;
Li, Zheng;
Xu, Guo-Liang;
Ding, Jianping

Publication type:

Article

Dynamics of 5-methylcytosine and 5-hydroxymethylcytosine during germ cell reprogramming.

Published in:

Cell Research, 2013, v. 23, n. 3, p. 329, doi. 10.1038/cr.2013.22

By:

Yamaguchi, Shinpei;
Hong, Kwonho;
Liu, Rui;
Inoue, Azusa;
Shen, Li;
Zhang, Kun;
Zhang, Yi

Publication type:

Article

PGC7, H3K9me2 and Tet3: regulators of DNA methylation in zygotes.

Published in:

Cell Research, 2013, v. 23, n. 1, p. 6, doi. 10.1038/cr.2012.117

By:

Kang, Jinsuk;
Kalantry, Sundeep;
Rao, Anjana

Publication type:

Article

Transcriptional activation of transposable elements in mouse zygotes is independent of Tet3-mediated 5-methylcytosine oxidation.

Published in:

Cell Research, 2012, v. 22, n. 12, p. 1640, doi. 10.1038/cr.2012.160

By:

Inoue, Azusa;
Matoba, Shogo;
Zhang, Yi

Publication type:

Article

Activity of Vsr endonucleases encoded by Neisseria gonorrhoeae FA1090 is influenced by MutL and MutS proteins.

Published in:

BMC Microbiology, 2018, v. 18, n. 1, p. N.PAG, doi. 10.1186/s12866-018-1243-3

By:

Adamczyk-Popławska, Monika;
Bandyra, Katarzyna;
Kwiatek, Agnieszka

Publication type:

Article

Increased ten-eleven translocation methylcytosine dioxygenase one in dorsal root ganglion contributes to inflammatory pain in CFA rats.

Published in:

Molecular Pain, 2022, p. 1, doi. 10.1177/17448069221143671

By:

Yun Liu;
Ling Zhang;
Zhen-hua Xu;
Jie Zhu;
Jia-ling Ma;
Yan-ping Gao;
Guang-Yin Xu

Publication type:

Article

Increased ten-eleven translocation methylcytosine dioxygenase one in dorsal root ganglion contributes to inflammatory pain in CFA rats.

Published in:

Molecular Pain, 2022, p. 1, doi. 10.1177/17448069221143671

By:

Liu, Yun;
Zhang, Ling;
Xu, Zhen-hua;
Zhu, Jie;
Ma, Jia-ling;
Gao, Yan-ping;
Xu, Guang-Yin

Publication type:

Article

Developmental regulation of DNA cytosine methylation at the immunoglobulin heavy chain constant locus.

Published in:

PLoS Genetics, 2019, v. 15, n. 2, p. 1, doi. 10.1371/journal.pgen.1007930

By:

Oudinet, Chloé;
Braikia, Fatima-Zohra;
Dauba, Audrey;
Santos, Joana M.;
Khamlichi, Ahmed Amine

Publication type:

Article

Charting oxidized methylcytosines at base resolution.

Published in:

Nature Structural & Molecular Biology, 2015, v. 22, n. 9, p. 656, doi. 10.1038/nsmb.3071

By:

Yardimci, Hasan;
Zhang, Yi

Publication type:

Article

New functions for DNA modifications by TET-JBP.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 11, p. 1061, doi. 10.1038/nsmb.2437

By:

Huang, Yun;
Rao, Anjana

Publication type:

Article

5-hmC in the brain is abundant in synaptic genes and shows differences at the exon-intron boundary.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 10, p. 1037, doi. 10.1038/nsmb.2372

By:

Khare, Tarang;
Pai, Shraddha;
Koncevicius, Karolis;
Pal, Mrinal;
Kriukiene, Edita;
Liutkeviciute, Zita;
Irimia, Manuel;
Jia, Peixin;
Ptak, Carolyn;
Xia, Menghang;
Tice, Raymond;
Tochigi, Mamoru;
Moréra, Solange;
Nazarians, Anaies;
Belsham, Denise;
Wong, Albert H C;
Blencowe, Benjamin J;
Wang, Sun Chong;
Kapranov, Philipp;
Kustra, Rafal

Publication type:

Article

5-formylcytosine and 5-carboxylcytosine reduce the rate and substrate specificity of RNA polymerase II transcription.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 8, p. 831, doi. 10.1038/nsmb.2346

By:

Kellinger, Matthew W;
Song, Chun-Xiao;
Chong, Jenny;
Lu, Xing-Yu;
He, Chuan;
Wang, Dong

Publication type:

Article

Changes of RNA m<sup>6</sup>A/m<sup>5</sup>C Modification Regulatory Molecules in Ferroptosis of T2DM Rat Pancreas.

Published in:

Cell Biochemistry & Biophysics, 2024, v. 82, n. 2, p. 1279, doi. 10.1007/s12013-024-01282-0

By:

Liu, Xiaoyu;
Wang, Nan;
Gu, Shiyan;
He, Zuoshun

Publication type:

Article

Substrate DNA length regulates the activity of TET 5‐methylcytosine dioxygenases.

Published in:

Cell Biochemistry & Function, 2023, v. 41, n. 6, p. 704, doi. 10.1002/cbf.3825

By:

Bhattacharya, Chayan;
Dey, Aninda Sundar;
Mukherji, Mridul

Publication type:

Article

Chromosomal distribution of H3K4me2, H3K9me2 and 5-methylcytosine: variations associated with polyploidy and hybridization in Brachiaria (Poaceae).

Published in:

Plant Cell Reports, 2016, v. 35, n. 6, p. 1359, doi. 10.1007/s00299-016-1969-z

By:

Paula, Cristina;
Souza Sobrinho, Fausto;
Techio, Vânia

Publication type:

Article

BiLSTM-5mC: A Bidirectional Long Short-Term Memory-Based Approach for Predicting 5-Methylcytosine Sites in Genome-Wide DNA Promoters.

Published in:

Molecules, 2021, v. 26, n. 24, p. 7414, doi. 10.3390/molecules26247414

By:

Cheng, Xin;
Wang, Jun;
Li, Qianyue;
Liu, Taigang

Publication type:

Article

Application of Ammonium Persulfate for Selective Oxidation of Guanines for Nucleic Acid Sequencing.

Published in:

Molecules, 2017, v. 22, n. 7, p. 1222, doi. 10.3390/molecules22071222

By:

Yafen Wang;
Chaoxing Liu;
Tingting Hong;
Fan Wu;
Shuyi Yu;
Zhiyong He;
Wuxiang Mao;
Xiang Zhou

Publication type:

Article

DNA methylation age-acceleration is associated with disease duration and age at onset in C9orf72 patients.

Published in:

Acta Neuropathologica, 2017, v. 134, n. 2, p. 271, doi. 10.1007/s00401-017-1713-y

By:

Zhang, Ming;
Tartaglia, Maria;
Moreno, Danielle;
Sato, Christine;
McKeever, Paul;
Weichert, Anna;
Keith, Julia;
Robertson, Janice;
Zinman, Lorne;
Rogaeva, Ekaterina

Publication type:

Article

Cytosine hydroxymethylation by TET enzymes: From the control of gene expression to the regulation of DNA repair mechanisms, and back.

Published in:

AIMS Biophysics, 2018, v. 5, n. 3, p. 182, doi. 10.3934/biophy.2018.3.182

By:

Lejart, Audrey;
Salbert, Gilles;
Huet, Sébastien

Publication type:

Article

Positive/negative ion-switching-based LC–MS/MS method for quantification of cytosine derivatives produced by the TET-family 5-methylcytosine dioxygenases.

Published in:

Biology Methods & Protocols, 2020, v. 5, n. 1, p. 1, doi. 10.1093/biomethods/bpaa019

By:

Dey, Aninda Sundar;
Ayon, Navid J;
Bhattacharya, Chayan;
Gutheil, William G;
Mukherji, Mridul

Publication type:

Article

Evaluation of Oxidative Stress activity, DNA Damage and Global DNA Methylation among Patients with Chronic Kidney Disease.

Published in:

Iraqi Journal of Science, 2024, v. 65, n. 9, p. 4963, doi. 10.24996/ijs.2024.65.9.13

By:

Hamid, Rehab Harith;
AL-Jumaily, Rakad M. Kh.

Publication type:

Article

Quantum-chemical investigation of nitrosonium complexes of complementary pair 1-methylcytosine-9-methylguanine.

Published in:

Russian Journal of Organic Chemistry, 2015, v. 51, n. 5, p. 664, doi. 10.1134/S1070428015050140

By:

Andreev, R.;
Borodkin, G.;
Shubin, V.

Publication type:

Article

DNA sequences performs as natural language processing by exploiting deep learning algorithm for the identification of N4-methylcytosine.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-020-80430-x

By:

Wahab, Abdul;
Tayara, Hilal;
Xuan, Zhenyu;
Chong, Kil To

Publication type:

Article

Modular affinity-labeling of the cytosine demethylation base elements in DNA.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-76544-x

By:

Wang, Fanny;
Zahid, Osama K.;
Ghanty, Uday;
Kohli, Rahul M.;
Hall, Adam R.

Publication type:

Article