Works about METABOLIC reprogramming

Results: 1216

Metabolic reprogramming of the neovascular niche promotes regenerative angiogenesis in proliferative retinopathy.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-60061-4

By:

Cagnone, Gael;
Pundir, Sheetal;
Betus, Charlotte;
Agnihotri, Tapan;
Ren, Anli;
-Kim, Jin Sung;
Harvey, Noémie-Rose;
Heckel, Emilie;
Chen, Mei Xi;
Situ, Anu;
Gaub, Perrine;
Kim, Nicholas;
Das, Ashim;
Leclerc, Severine;
Wünnemann, Florian;
Berillon, Louis;
Andelfinger, Gregor;
Crespo-Garcia, Sergio;
Dubrac, Alexandre;
Rezende, Flavio A.

Publication type:

Article

Non-parenchymal cells: key targets for modulating chronic liver diseases.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1576739

By:

Yang, Tongwang;
Gu, Zhiyun;
Feng, Juan;
Shan, Juanjuan;
Qian, Cheng;
Zhuang, Na

Publication type:

Article

Loss of STIM2, but not of STIM1, drives colorectal cancer metastasis through metabolic reprogramming and the ATF4 ER stress pathway.

Published in:

Science Signaling, 2025, v. 18, n. 892, p. 1, doi. 10.1126/scisignal.ads6550

By:

Pathak, Trayambak;
Benson, J. Cory;
Johnson, Martin T.;
Xin, Ping;
Abdelnaby, Ahmed Emam;
Walter, Vonn;
Koltun, Walter A.;
Yochum, Gregory S.;
Hempel, Nadine;
Trebak, Mohamed

Publication type:

Article

Comprehensive multi-omics analysis of nucleotide metabolism: elucidating the role and prognostic significance of UCK2 in bladder cancer.

Published in:

Functional & Integrative Genomics, 2025, v. 25, n. 1, p. 1, doi. 10.1007/s10142-025-01642-w

By:

Guo, Yadong;
Lin, Ziyou;
Zhang, Wentao;
Chen, Haotian;
Chen, Yuxin;
Liu, Yongqiang;
Shan, Zezhi;
Mao, Shiyu;
Yao, Xudong

Publication type:

Article

m5C RNA methylation in cancer: from biological mechanism to clinical perspectives.

Published in:

European Journal of Medical Research, 2025, v. 30, n. 1, p. 1, doi. 10.1186/s40001-025-02812-z

By:

Yuan, Fang;
Xia, Yuxuan;
Huang, Zhen;
Gao, Huihui;
Bian, Yuqi;
Zhou, Xiangqin

Publication type:

Article

Systematic proteomic and small RNA profiling of extracellular vesicles from cattle infected with a naturally occurring buparvaquone-resistant strain of Theileria annulata and from uninfected controls.

Published in:

Parasites & Vectors, 2025, v. 18, n. 1, p. 1, doi. 10.1186/s13071-025-06834-8

By:

Chai, Yijun;
Che, Jin;
Wang, Jinming;
Guan, Guiquan;
Yin, Hong

Publication type:

Article

Lipid droplet accumulation in microglia and their potential roles.

Published in:

Lipids in Health & Disease, 2025, v. 24, n. 1, p. 1, doi. 10.1186/s12944-025-02633-3

By:

Li, Yunxia;
Zhao, Qi;
Wang, Yan;
Du, Wenyi;
Yang, Riyun;
Wu, Jian;
Li, Yi

Publication type:

Article

A pyrimidine metabolism-related gene signature for prognosis prediction and immune microenvironment description of breast cancer.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06700-2

By:

Wang, Han;
Zhou, Ziling;
Zhong, Hanyi;
Wang, Shoutang;
Shen, Kunwei;
Huang, Renhong;
Wang, Ruo;
Wang, Zheng

Publication type:

Article

TRIM65 regulates glucose metabolic reprogramming to promote glioma cell proliferation via ubiquitination and degradation of AMPK.

Published in:

NPJ Precision Oncology, 2025, v. 9, n. 1, p. 1, doi. 10.1038/s41698-025-00964-z

By:

Li, Ming-Hui;
Wang, Tao;
Guan, Xiao-Hui;
Yu, Zhen-Ping;
Han, Xin-Hao;
Qu, Xin-Hui;
Chen, Zhi-Ping;
Han, Xiao-Jian;
Wang, Xiao-Yu

Publication type:

Article

Super-enhancers orchestrate transcriptional dysregulation and metabolic reprogramming in uveal melanoma.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-08338-8

By:

Pan, Hui;
Shao, Weihuan;
Wang, Huixue;
Ge, Shengfang;
Zhang, Lingyu;
Xu, Xiaofang;
Wang, Yefei;
Zhuang, Ai

Publication type:

Article

Metabolic acclimation to warming links unexpected immune activation and sexual dimorphism attenuation in Xenopus tropicalis.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-08340-0

By:

Li, Jiaying;
Zhu, Jiahao;
Budian, Ayi;
Zeng, Yiwei;
Wang, Shouhong;
Gong, Yuzhou;
Wang, Xungang;
Zhao, Longhui;
Tang, Na;
Zheng, Si;
Han, Rong;
Zhan, Songping;
Xie, Ting;
Chen, Ting;
Li, Xiangzhen;
Jiang, Jianping

Publication type:

Article

The metabolic shift of glutaminase 2 to glutaminase 1 promotes LGR5 + progenitor cell proliferation in liver cirrhosis.

Published in:

Cellular & Molecular Life Sciences, 2025, v. 82, n. 1, p. 1, doi. 10.1007/s00018-025-05772-z

By:

Kong, Defu;
Zhou, Qi;
He, Kang;
Heegsma, Janette;
Blokzijl, Hans;
de Meijer, Vincent E;
Faber, Klaas Nico

Publication type:

Article

Acute kidney injury through a metabolic lens: pathological reprogramming mechanisms and clinical translation potential.

Published in:

Frontiers in Physiology, 2025, p. 1, doi. 10.3389/fphys.2025.1602865

By:

Gao, Jingli;
Huang, Liuyifei;
Zhang, Yuzhan;
Wei, Lei;
Yu, Zhixiang;
Xing, Yan;
Yuan, Jinguo;
Ning, Xiaoxuan;
Sun, Shiren

Publication type:

Article

Unraveling the role of GPCR signaling in metabolic reprogramming and immune microenvironment of lung adenocarcinoma: a multi-omics study with experimental validation.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1606125

By:

Wang, Zhaoxuan;
Wang, Cheng;
Zhao, Shilei;
Gu, Chundong

Publication type:

Article

Ferroptosis in osteoarthritis: metabolic reprogramming, immunometabolic crosstalk, and targeted intervention strategies.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1604652

By:

Xia, Shenglin;
Li, Li;
Shi, Zhexiong;
Sun, Nianyi;
He, Yu

Publication type:

Article

EPHX2 overexpression deters the advancement of clear cell renal cell carcinoma via lipid metabolism reprogramming.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1541429

By:

Guan, Bo;
Huang, Cong;
He, Jun;
Shan, Weimin;
Cui, Di;
Li, Xiaowei;
Liang, Chaozhao;
Hao, Zongyao

Publication type:

Article

Targeting metabolic reprogramming to overcome immune tolerance in melanoma immunotherapy.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1597770

By:

Wang, Qinchen;
Shi, Lei;
Shi, Daoming;
Tai, Ningzheng;
Wang, Xu

Publication type:

Article

LKB1 regulates ILC3 postnatal development and effector function through metabolic programming.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1587256

By:

Zhang, Huasheng;
Zhao, Linfeng;
Zhang, Qingbing;
Hu, Lin;
Su, Xiaohui;
Sun, Jiping;
Shen, Lei

Publication type:

Article

Energy metabolism in cardiovascular diseases: unlocking the hidden powerhouse of cardiac pathophysiology.

Published in:

Frontiers in Endocrinology, 2025, p. 1, doi. 10.3389/fendo.2025.1617305

By:

Chen, Li;
Chen, Mingtai;
Yang, Xinrui;
Hu, Yuanli;
Qiu, Caiwei;
Fu, Youyou;
Lan, Xiaoyu;
Luo, Gang;
Liu, Qiuyu;
Liu, Mengnan

Publication type:

Article

Targeting amino acid in tumor therapy.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1582116

By:

Ge, Mingpai;
Xu, Yuan;
Cui, Lu;
Huang, Enyuan;
Liu, Zhaorui;
Yin, Kai

Publication type:

Article

Integrated transcriptomics and machine learning reveal REN as a dual regulator of tumor stemness and NK cell evasion in Wilms tumor progression.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1612987

By:

Cao, Qingfei;
Li, Junyi;
Zou, Yunfei;
Xu, Changwen;
Tang, Huihui;
Chen, Meixue

Publication type:

Article

Navigating the role of protein lactylation in prostate cancer and its implications for immunotherapy.

Published in:

Journal of Cancer, 2025, v. 16, n. 8, p. 2706, doi. 10.7150/jca.114137

By:

Dongzhang Li;
Kaifeng Wang;
Guantao Lou;
Wangjian Li;
Quan Ma;
Yu'e Liu;
Yongliang Chen

Publication type:

Article

Mechanistic insights into hypoxia‐induced metabolic reprogramming in colorectal cancer through genome‐scale modeling.

Published in:

Biotechnology Progress, 2025, v. 41, n. 3, p. 1, doi. 10.1002/btpr.70002

By:

Omer, Sonal;
Sridhar, Subasree;
Karunagaran, D.;
Suraishkumar, G. K.

Publication type:

Article

Research advances in the study of traditional Chinese medicine formula granules on signaling pathway-mediated disease mechanisms.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1609211

By:

Gu, Zhuo-Xu;
Wang, Zhong-Hao;
Zhang, Xian-Quan;
Zhou, Guang-Hui;
Liang, Gui-Hong;
Zeng, Ling-Feng;
Liu, Jun

Publication type:

Article

Gestational saccharin consumption disrupts gut-brain axis glucose homeostasis control in adolescent offspring rats in a sex-dependent manner.

Published in:

Biology of Sex Differences, 2025, v. 16, n. 1, p. 1, doi. 10.1186/s13293-025-00724-5

By:

Pacheco-Sánchez, Beatriz;
Melgar-Locatelli, Sonia;
López-Merchán, Raquel;
Benítez-Marín, María José;
Blasco-Alonso, Marta;
González-Mesa, Ernesto;
Tovar, Rubén;
Rubio, Pablo;
Suárez, Juan;
Sanjuan, Carlos;
de Fonseca, Fernando Rodríguez;
Alén, Francisco;
de Ceglia, Marialuisa;
Rivera, Patricia

Publication type:

Article

Enhanced resistance to Listeria infection in mice surviving sepsis: the role of lipid metabolism and myeloid cell reprogramming.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1588987

By:

Watanabe, Haruki;
Song, Tengfei;
Choi, Jaewoo;
Lee, Moses;
Choi, Kwangmin;
Kim, Junhwan;
Sherry, Barbara;
Diamond, Betty;
Zou, Yong-Rui;
Son, Myoungsun

Publication type:

Article

Metabolic profiling of glioblastoma and identification of G0S2 as a metabolic target.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1572040

By:

Kang, Jianlei;
Xu, Yujie;
Zhao, Qitai;
Wang, Ying;
He, Zhenyan;
Xu, Xin

Publication type:

Article

The potential of ME1 in guiding immunotherapeutic strategies for ovarian cancer: insights from pan-cancer research.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1571842

By:

Wei, Jiahui;
Wang, Ming;
Xu, Shuiqing;
Tusufuhan, Paizigul;
Wu, Yumei

Publication type:

Article

Outer membrane vesicles derived from probiotic Escherichia coli Nissle 1917 promote metabolic remodeling and M1 polarization of RAW264.7 macrophages.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1501174

By:

Ma, DongXue;
Zhang, YuXin;
Zhang, Jia;
Shi, Jun;
Gao, ShanHu;
Long, Fei;
Wang, Xin;
Pu, XingYu;
Sun, Jiayao;
Liang, Shuang;
Cannon, Richard D.;
Villas-Boas, Silas;
Han, Ting-Li

Publication type:

Article

Aristolochic acid I orchestrates multi-organ carcinogenesis through apoptotic pathway in bladder, kidney, and liver cancers: a multi-omics dissection.

Published in:

Environmental Sciences Europe, 2025, v. 37, n. 1, p. 1, doi. 10.1186/s12302-025-01146-1

By:

Zhang, Bitian;
Leung, Ping-Chung;
Wong, Chun-Kwok;
Wang, Dongjie

Publication type:

Article

Exercise orchestrates systemic metabolic and neuroimmune homeostasis via the brain–muscle–liver axis to slow down aging and neurodegeneration: a narrative review.

Published in:

European Journal of Medical Research, 2025, v. 30, n. 1, p. 1, doi. 10.1186/s40001-025-02751-9

By:

Kong, Jianda;
Xie, Yingao;
Fan, Rao;
Wang, Qinglu;
Luo, Ying;
Dong, Panpan

Publication type:

Article

Multi-omics-Based Construction of ncRNA-Gene-Metabolite Networks Provides New Insights Into Metabolic Regulation Under Salt Stress in Rice.

Published in:

Rice (19398425), 2025, v. 18, n. 1, p. 1, doi. 10.1186/s12284-025-00811-6

By:

Tong, Haiyang;
Wang, Chao;
Han, Xiaoqian;
Sun, Qihao;
Luo, Enxi;
Yang, Chao;
Xu, Guo;
Ou, Xumin;
Li, Shixuan;
Zhang, Jianing;
Yang, Jun

Publication type:

Article

Lipid droplet accumulation in microglia and their potential roles.

Published in:

Lipids in Health & Disease, 2025, v. 24, n. 1, p. 1, doi. 10.1186/s12944-025-02633-3

By:

Li, Yunxia;
Zhao, Qi;
Wang, Yan;
Du, Wenyi;
Yang, Riyun;
Wu, Jian;
Li, Yi

Publication type:

Article

Activation of mechanosensitive ion channel Piezo1 linking metabolic reprogramming and pro-inflammatory responses in hepatocellular carcinoma.

Published in:

Cell Communication & Signaling, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12964-025-02289-7

By:

Mo, Juanfen;
Zhang, YuXuan;
Cao, Chenxi;
Zheng, WeiLi;
Zheng, Li;
Wang, Xiaoguang;
Wang, Shiyue;
Wu, Jiayuan;
Bao, Yi

Publication type:

Article

Single-cell multi-omics reveals that FABP1 + renal cell carcinoma drive tumor angiogenesis through the PLG-PLAT axis under fatty acid reprogramming.

Published in:

Molecular Cancer, 2025, v. 24, n. 1, p. 1, doi. 10.1186/s12943-025-02377-9

By:

Wang, Yiqiu;
Liang, Yingchun;
Li, Min;
Lu, Jiayi;
Zhou, Sian;
Yu, Yaoyu;
Yang, Changwei;
Hou, Xinhuang

Publication type:

Article

The role and mechanism of fatty acid oxidation in cancer drug resistance.

Published in:

Cell Death Discovery, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41420-025-02554-1

By:

Lei, Yun;
Cai, Shuang;
Zhang, Jia-Kui;
Ding, Si-Qi;
Zhang, Zhan-He;
Zhang, Chun-Dong;
Dai, Dong-Qiu;
Li, Yong-Shuang

Publication type:

Article

Phthalates unleashed: decoding ovarian carcinogenesis through multi-omics networks, single-cell insights, and molecular docking.

Published in:

Journal of Ovarian Research, 2025, v. 18, n. 1, p. 1, doi. 10.1186/s13048-025-01710-6

By:

Yang, Junchan;
Luo, Min;
Wang, Hongjun;
Huang, Jinfa

Publication type:

Article

ALDOC and PGK1 coordinately induce glucose metabolism reprogramming and promote development of colorectal cancer.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01252-z

By:

Huang, Liyong;
Tong, Yixin;
Li, Xu;
Wang, Wei;
Wang, Zhen;
Chen, Bingchen;
E., Jifu;
Zhou, Ruzhen;
Wang, Hantao;
He, Jinghu

Publication type:

Article

Dietary Supplementation of Lactobacillus reuteri Modulates Amino Acid Metabolism and Extracellular Matrix in the Gut–Liver Axis of Weaned Piglets.

Published in:

Animals (2076-2615), 2025, v. 15, n. 11, p. 1567, doi. 10.3390/ani15111567

By:

He, Yiyi;
Wei, Yangyang;
Ruan, Shihui;
Wu, Qiwen;
Xiong, Yunxia;
Wang, Li;
Jiang, Zongyong;
Xu, E;
Yi, Hongbo

Publication type:

Article

Lipid Metabolism Reprogramming in Tumor-Associated Macrophages Modulates Their Function in Primary Liver Cancers.

Published in:

Cancers, 2025, v. 17, n. 11, p. 1858, doi. 10.3390/cancers17111858

By:

Oliviero, Barbara;
Caretti, Anna;
Mondelli, Mario U.;
Mantovani, Stefania

Publication type:

Article

Lymphatic Metastasis of Esophageal Squamous Cell Carcinoma: The Role of NRF2 and Therapeutic Strategies.

Published in:

Cancers, 2025, v. 17, n. 11, p. 1853, doi. 10.3390/cancers17111853

By:

Li, Yahui;
Ladd, Zachary;
Xiong, Zhaohui;
Bui-Linh, Candice;
Paiboonrungruang, Chorlada;
Subramaniyan, Boopathi;
Li, Huan;
Wang, Haining;
Balch, Curt;
Shersher, David D.;
Spitz, Francis;
Chen, Xiaoxin

Publication type:

Article

Cellular Heterogeneity and IL-17 Pathway Dynamics Reveal Insights into the Transition from Ulcerative Colitis to Colorectal Cancer Through scRNA-Seq Analysis.

Published in:

Journal of Inflammation Research, 2025, v. 18, p. 6927, doi. 10.2147/JIR.S505313

By:

Li, Yaxian;
Sun, Ruochuan;
Wang, Xiaodong;
Ma, Mengdi;
Wang, Huizhen;
Yang, Bo;
Lu, Yida;
Li, Yongxiang

Publication type:

Article

Brief Weekly Magnetic Field Exposure Enhances Avian Oxidative Muscle Character During Embryonic Development.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 11, p. 5423, doi. 10.3390/ijms26115423

By:

Yap, Jasmine Lye Yee;
Wu, Kwan Yu;
Tai, Yee Kit;
Fong, Charlene Hui Hua;
Manazir, Neha;
Paul, Anisha Praiselin;
Yeo, Olivia;
Franco-Obregón, Alfredo

Publication type:

Article

PBX3-HMGCR Axis Promotes Hepatocellular Carcinoma Progression Through Enhancing De Novo Cholesterol Biosynthesis.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 11, p. 5210, doi. 10.3390/ijms26115210

By:

Zhang, Xia;
Qiu, Li;
Zhang, Lei;
Li, Wenfang;
Xiang, Debing;
Wang, Jian;
Wu, Shourong;
Kasim, Vivi

Publication type:

Article

Clinical Significance of NUDT1 (MTH1) Across Cancer Types.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 11, p. 5137, doi. 10.3390/ijms26115137

By:

Misiak, Radosław;
Białkowski, Karol;
Dondajewska, Ewelina

Publication type:

Article

HIF-1α-Mediated Disruption of Cellular Junctions: The Impact of Hypoxia on the Tumor Microenvironment and Invasion.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 11, p. 5101, doi. 10.3390/ijms26115101

By:

Springer, Michael;
Burakgazi, Zeynep Aydin;
Domukhovska, Anastasiia;
Nafchi, Ben;
Beary, Michael C.;
Acquisto, Arielle;
Acquisto, Juliette;
Komarov, Vladyslav;
Jensen, Madison;
Gulledge, Brandon;
Poplavskyi, Maksym;
Uddin, Md Gias;
Rayan, Gamal;
Zucker, Shoshanna N.

Publication type:

Article

Role of Ischemia/Reperfusion and Oxidative Stress in Shock State.

Published in:

Cells (2073-4409), 2025, v. 14, n. 11, p. 808, doi. 10.3390/cells14110808

By:

Vázquez-Galán, Yarielis Ivette;
Guzmán-Silahua, Sandra;
Trujillo-Rangel, Walter Ángel;
Rodríguez-Lara, Simón Quetzalcoatl

Publication type:

Article

Metabolic Reprogramming Triggered by Fluoride in U-87 Glioblastoma Cells: Implications for Tumor Progression?

Published in:

Cells (2073-4409), 2025, v. 14, n. 11, p. 800, doi. 10.3390/cells14110800

By:

Żwierełło, Wojciech;
Maruszewska, Agnieszka;
Skórka-Majewicz, Marta;
Wszołek, Agata;
Gutowska, Izabela

Publication type:

Article

Mitochondrial Dysfunction: The Silent Catalyst of Kidney Disease Progression.

Published in:

Cells (2073-4409), 2025, v. 14, n. 11, p. 794, doi. 10.3390/cells14110794

By:

Pavlović, Nikola;
Križanac, Marinela;
Kumrić, Marko;
Vukojević, Katarina;
Božić, Joško

Publication type:

Article

Systematic proteomic and small RNA profiling of extracellular vesicles from cattle infected with a naturally occurring buparvaquone-resistant strain of Theileria annulata and from uninfected controls.

Published in:

Parasites & Vectors, 2025, v. 18, n. 1, p. 1, doi. 10.1186/s13071-025-06834-8

By:

Chai, Yijun;
Che, Jin;
Wang, Jinming;
Guan, Guiquan;
Yin, Hong

Publication type:

Article