Works matching DE "METABOLIC reprogramming"

Results: 1313

Narirutin treatment accelerates the process of diabetic wound repair by regulating phenotype switching of macrophages through affecting metabolic reprogramming.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1614967

By:

Liu, Liang;
Wang, Han;
Zhou, Juan;
Lu, Jing;
Zhang, Yan;
Liu, Haiyan;
Lu, Li

Publication type:

Article

Metabolic reprogramming in colorectal cancer: a review of aerobic glycolysis and its therapeutic implications for targeted treatment strategies.

Published in:

Cell Death Discovery, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41420-025-02623-5

By:

Pang, Boran;
Wu, Hao

Publication type:

Article

CYP51A1 in health and disease: from sterol metabolism to regulated cell death.

Published in:

Cell Death Discovery, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41420-025-02621-7

By:

Chen, Fangquan;
Liang, RuiRui;
Zhang, Jieting;
Kang, Rui;
Tang, Daolin;
Liu, Jiao

Publication type:

Article

The Toxicological Effects, Toxin-Producing Performance, and Molecular Mechanism of Marine Microalgae in Response to Environmental Estrogens: A Review.

Published in:

Water (20734441), 2025, v. 17, n. 13, p. 1922, doi. 10.3390/w17131922

By:

Guo, Long;
Chen, Wenqing;
Zhang, Chunyun;
Wang, Yuanyuan;
Chen, Guofu

Publication type:

Article

Cancer Stem Cells Connecting to Immunotherapy: Key Insights, Challenges, and Potential Treatment Opportunities.

Published in:

Cancers, 2025, v. 17, n. 13, p. 2100, doi. 10.3390/cancers17132100

By:

Mathan, Sivapar V.;
Singh, Rana P.

Publication type:

Article

Andrographolide Mitigates Inflammation and Reverses UVB-Induced Metabolic Reprogramming in HaCaT Cells.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6508, doi. 10.3390/ijms26136508

By:

Manosalva, Carolina;
Alarcón, Pablo;
Grassau, Lucas;
Cortés, Carmen;
Hancke, Juan L.;
Burgos, Rafael A.

Publication type:

Article

Circadian Clock Deregulation and Metabolic Reprogramming: A System Biology Approach to Tissue-Specific Redox Signaling and Disease Development.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6267, doi. 10.3390/ijms26136267

By:

Konakchieva, Rossitza;
Mladenov, Mitko;
Konaktchieva, Marina;
Sazdova, Iliyana;
Gagov, Hristo;
Nikolaev, Georgi

Publication type:

Article

Subtherapeutic Dose of Ionizing Radiation Reprograms the Pre-Metastatic Lung Niche, Accelerating Its Formation and Promoting Metastasis.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6145, doi. 10.3390/ijms26136145

By:

Oliveira, Paula de;
Vala, Inês Sofia;
Faísca, Pedro;
Guimaraes, Joao C;
Pina, Filomena;
Poli, Esmeralda;
Diegues, Isabel;
Osório, Hugo;
Matthiesen, Rune;
Serre, Karine;
Constantino Rosa Santos, Susana

Publication type:

Article

Targeting Prostate Cancer Metabolism Through Transcriptional and Epigenetic Modulation: A Multi-Target Approach to Therapeutic Innovation.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6013, doi. 10.3390/ijms26136013

By:

Espitia-Pérez, Pedro Juan;
Espitia-Perez, Lyda Marcela;
Negrette-Guzmán, Mario

Publication type:

Article

Rewired glycolysis by DTL accelerates oncometabolite L-lactate generation to promote breast cancer progression.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1583752

By:

Liu, Yuhao;
Li, Jinting;
Cao, Yiren;
Lv, Mengzhu

Publication type:

Article

Lactate and lactylation: emerging roles in autoimmune diseases and metabolic reprogramming.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1589853

By:

Liu, Wenjun;
Yang, Ruhui;
Zhan, Yuxin;
Yang, Xuanyu;
Zeng, Haimin;
Chen, Bofan;
Zeng, Jiahao;
Hu, Tianheng;
Hu, Jie;
Xiao, Qi;
Shao, Yinjin;
Chen, Xiang

Publication type:

Article

Liquid-liquid phase separation: an emerging perspective on the tumorigenesis, progression, and treatment of tumors.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1604015

By:

Jian, Qin;
Xu, Qi;
Xiang, Sirui;
Wang, Rongrong;
Wang, Chuchu;
Zhang, Boxun;
Li, Ruli;
Lin, Junzhi;
Zheng, Chuan

Publication type:

Article

Multi-omics analysis reveals the role of ribosome biogenesis in malignant clear cell renal cell carcinoma and the development of a machine learning-based prognostic model.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1602898

By:

Xie, Zhouzhou;
Peng, Shansen;
Wang, Jiongming;
Huang, Yueting;
Zhou, Xiaoqi;
Zhang, Guihao;
Jiang, Huiming;
Zhong, Kaihua;
Feng, Lingsong;
Chen, Nanhui

Publication type:

Article

Unraveling CRP/cAMP-mediated metabolic regulation in Escherichia coli persister cells.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.99735

By:

Han G. Ngo;
Mohiuddin, Sayed Golam;
Ananda, Aina;
Orman, Mehmet

Publication type:

Article

Modulation of lipid metabolism by exercise: exploring its potential as a therapeutic target in cancer endocrinology.

Published in:

Frontiers in Endocrinology, 2025, p. 1, doi. 10.3389/fendo.2025.1580559

By:

Liu, Haodong;
Yang, Tong;
Choi, Seongbeom

Publication type:

Article

Baculovirus enhances arginine uptake and induces mitochondrial autophagy to promote viral proliferation.

Published in:

PLoS Pathogens, 2025, v. 21, n. 7, p. 1, doi. 10.1371/journal.ppat.1013331

By:

Fei, Shigang;
Xia, Junming;
Huang, Yigui;
Zhou, Minyang;
Xie, Biying;
Kong, Yibing;
Swevers, Luc;
Sun, Jingchen;
Feng, Min

Publication type:

Article

Correction to: Cancer-associated fibroblasts and metabolic reprogramming predict pathologic response to neoadjuvant PD-1 blockade in resected non-small cell lung cancer.

Published in:

2025

By:

Zhao, Jiaqi;
Liu, Maolin;
Zhu, Chongmei;
Li, Zhuolin;
Liu, Zuhui;
Abulizi, Dilimulati;
Liu, Siqing;
Wang, Xin;
Yang, Haoxian;
Hou, Xue

Publication type:

Correction Notice

Cancer-associated fibroblasts and metabolic reprogramming predict pathologic response to neoadjuvant PD-1 blockade in resected non-small cell lung cancer.

Published in:

Cellular Oncology (2211-3428), 2025, v. 48, n. 4, p. 1105, doi. 10.1007/s13402-025-01067-4

By:

Zhao, Jiaqi;
Liu, Maolin;
Zhu, Chongmei;
Li, Zhuolin;
Liu, Zuhui;
Abulizi, Dilimulati;
Liu, Siqing;
Wang, Xin;
Yang, Haoxian;
Hou, Xue

Publication type:

Article

CAF-derived GLUT1 and its role in modulating ovarian cancer progression: a multi-dimensional analysis of the tumor microenvironment.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-08380-6

By:

Zhang, Dandan;
Li, Jinke;
Xu, Xingyuan;
Wang, Xiaoxue;
Lou, Yingze;
Zhou, Xin;
Zhang, Kai

Publication type:

Article

Research trends of protein palmitoylation in cancer from 2004 to 2024: a bibliometric and visualization analysis.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1571870

By:

Peng, Yufeng;
Peng, Kewei;
Wang, Yi;
Li, Luyao;
Lu, Yuefei

Publication type:

Article

SIRT5-modified human umbilical cord mesenchymal stem cells loaded with antioxidant polydopamine nanozyme enhance parpi resistance in ovarian cancer via fatty acid metabolism reprogramming.

Published in:

Journal of Nanobiotechnology, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12951-025-03516-6

By:

Zhang, Jin;
Du, Xiuluan;
Dai, Xin;
Liu, Yanxiang;
Guo, Kai;
Gu, Donghua

Publication type:

Article

Abnormal chenodexycholic acid metabolism programming promotes cartilage matrix degradation in male adult offspring rats induced by prenatal caffeine exposure.

Published in:

Toxicology Research, 2025, v. 14, n. 3, p. 1, doi. 10.1093/toxres/tfaf063

By:

Li, Bin;
Gao, Hui;
Xiao, Hao;
He, Hangyuan;
Ni, Qubo;
Li, Qingxian;
Wang, Hui;
Chen, Liaobin

Publication type:

Article

Metabolic reprogramming in melanoma therapy.

Published in:

Cell Death Discovery, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41420-025-02617-3

By:

Shen, Dongliang;
Zhang, Lu;
Li, Shun;
Tang, Liling

Publication type:

Article

Liposome-encapsulated AICAR hydrogel regulates macrophage metabolic reprogramming via SIK1 activation to alleviate osteoarthritis.

Published in:

Journal of Nanobiotechnology, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12951-025-03543-3

By:

Fu, Yong;
Hou, Jiahui;
Yang, Qinmeng;
Lin, Yanpeng;
Rui, Nie;
Wang, Jun;
Wu, Hangtian;
Yu, Bin

Publication type:

Article

Energy imbalance in oPOI ovarian granulosa cells is linked to reduced glucose bioavailability and metabolism.

Published in:

Reproductive Biology & Endocrinology, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12958-025-01426-8

By:

Marynowicz, Weronika;
Głód, Paulina;
Maduzia, Dawid;
Gogola-Mruk, Justyna;
Ptak, Anna

Publication type:

Article

Recent advances in nanomedicine targeting amino acid metabolism for anti-tumor therapy.

Published in:

Journal of Nanoparticle Research, 2025, v. 27, n. 6, p. 1, doi. 10.1007/s11051-025-06344-9

By:

Pang, Cui;
Song, Xueru;
Luo, Yizhou;
Li, Huiyu;
Guo, Wenqi;
Liu, Wanyi;
Feng, Hui;
Wu, Yizhang;
Chu, Xiaoyuan;
Lei, Zengjie

Publication type:

Article

Hippo/YAP signaling pathway in colorectal cancer: regulatory mechanisms and potential drug exploration.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1545952

By:

Zhang, Lingqiu;
Zhang, Fan;
Liang, Haimei;
Qin, Xiangling;
Mo, Yuemi;
Chen, Shiyi;
Xie, Jinling;
Hou, Xiaotao;
Deng, Jiagang;
Hao, Erwei;
Du, Zhengcai

Publication type:

Article

DNMBP-AS1/hsa-miR-30a-5p/PGC1α axis suppresses tumor progression of colorectal cancer by inhibiting PKM2-mediated Warburg effect and enhance anti-PD-1 therapy efficacy.

Published in:

Cell Death Discovery, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41420-025-02561-2

By:

Wang, Tianxiao;
Zhang, Wenxin;
Liu, Jiafeng;
Mao, Xiang;
Wang, Xinhai;
Li, Jiyifan;
Huang, Yuxin;
Wu, Zimei;
Chen, Haifei;
Shi, Huanying;
Qi, Huijie;
Chen, Lu;
Li, Qunyi

Publication type:

Article

Lactate and lactylation: novel perspectives on fibrosis pathogenesis and therapeutic directions.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06748-0

By:

Liang, Huanwei;
Xu, Linlin;
Yang, Yi

Publication type:

Article

Glycolytic control proteins in urinary extracellular vesicles are elevated during kidney transplant T cell-mediated rejection.

Published in:

BMC Nephrology, 2025, v. 26, n. 1, p. 1, doi. 10.1186/s12882-025-04196-y

By:

Leung, P.Y.M.;
Graver, A.S.;
Katerelos, M.;
Skene, A.;
Whitlam, J.B.;
Power, D.A.;
Mount, P.F.

Publication type:

Article

Ghrelin-induced neuronal NPY promotes brain metastasis in lung cancer patients with low BMI.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-60730-4

By:

Tyagi, Abhishek;
Wu, Shih-Ying;
Kim, Jee-Won;
Deshpande, Ravindra Pramod;
Wu, Kerui;
Smith, Eleanor C.;
Banna, Giuseppe L.;
Watabe, Kounosuke

Publication type:

Article

Non-canonical nuclear function of glutaminase cooperates with Wnt signaling to drive EMT during neural crest development.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-58573-0

By:

Nekooie Marnany, Nioosha;
Dady, Alwyn;
Duband-Goulet, Isabelle;
Relaix, Frédéric;
Motterlini, Roberto;
Foresti, Roberta;
Dufour, Sylvie;
Duband, Jean-Loup

Publication type:

Article

Recent advances in dermal fibroblast senescence and skin aging: unraveling mechanisms and pioneering therapeutic strategies.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1592596

By:

Nan, Li;
Guo, Pengchao;
Hui, Wang;
Xia, Fang;
Yi, Chenggang

Publication type:

Article

Evaluation of Lipid Metabolism Reprogramming Markers (Star Related Lipid Transfer Domain Containing 3 (STARD3), Apolipoprotein C1 (APOC1), Sterol Regulatory Element Binding Protein 2 (SREBP2) In Progression of Hepatitis C Virus-Induced Hepatocellular Carcinoma

Published in:

Egyptian Journal of Hospital Medicine, 2025, v. 99, n. 1, p. 1415, doi. 10.21608/ejhm.2025.420973

By:

Allah, Marwa S. Abd;
Soliman, Amira E.

Publication type:

Article

SREBP-1 in obesity-induced breast cancer: mechanisms and therapeutic perspectives.

Published in:

Molecular Biology Reports, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s11033-025-10775-x

By:

Tiwari, Urvashi;
Akhtar, Salman;
Mir, Snober S;
Khan, Mohammad Kalim Ahmad

Publication type:

Article

Exploring Stressors: Impact on Cellular Organelles and Implications for Cellular Functions.

Published in:

Stresses, 2025, v. 5, n. 2, p. 26, doi. 10.3390/stresses5020026

By:

Zayani, Zoofa;
Matinahmadi, Arash;
Tavakolpournegari, Alireza;
Bidooki, Seyed Hesamoddin

Publication type:

Article

Circular RNA circIGF1R controls cardiac fibroblast proliferation through regulation of carbohydrate metabolism.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-07167-3

By:

Schmidt, Arne;
Schmidt, Kevin;
Groß, Sonja;
Lu, Dongchao;
Xiao, Ke;
Neufeldt, Dimyana;
Cushman, Sarah;
Lehmann, Nele;
Thum, Sabrina;
Pfanne, Angelika;
Just, Annette;
Pich, Andreas;
Heinz, Alexander;
Hiller, Karsten;
Hunkler, Hannah Jill;
Tan, Wilson Lek Wen;
Foo, Roger;
Bär, Christian;
Thum, Thomas;
Jung, Mira

Publication type:

Article

Naphthenic Acid Fraction Components-Induced Metabolic and Mitochondrial Alterations in Rat Hepatoma Cells: Monitoring Metabolic Reprogramming with Tryptophan–Kynurenine Ratio.

Published in:

Journal of Xenobiotics, 2025, v. 15, n. 3, p. 61, doi. 10.3390/jox15030061

By:

Jamshed, Laiba;
Marie-Lucas, Amica;
Perono, Genevieve A.;
Tomy, Gregg T.;
Petrik, Jim J.;
Frank, Richard A.;
Hewitt, L. Mark;
Thomas, Philippe J.;
Holloway, Alison C.

Publication type:

Article

Targeting glutamine metabolism as a potential target for cancer treatment.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-025-03430-7

By:

Zou, Wenxuan;
Han, Zitao;
Wang, Zihan;
Liu, Qian

Publication type:

Article

Comprehensive multi-omics and biochemical analysis to elucidate the molecular response mechanisms of gill and kidney tissues under acute salinity stress in Pseudobagras ussuriensis.

Published in:

BMC Genomics, 2025, v. 26, n. 1, p. 1, doi. 10.1186/s12864-025-11773-w

By:

Liu, Yu;
Gu, Libo;
Zhao, Jun;
Liu, Mengzhu;
Wang, Ke;
Zhou, Qingbo;
Cao, Yang;
Hu, Ruyi;
Wang, Weiwei;
Liu, Qing

Publication type:

Article

MASLD and MASH Risk: Does Losing Obesity Reverse the Metabolic Footprint.

Published in:

Liver International, 2025, v. 45, n. 7, p. 1, doi. 10.1111/liv.70161

By:

van Kleef, Laurens A.;
Pustjens, Jesse;
Brouwer, Willem Pieter

Publication type:

Article

Glucose metabolism and immune dysregulation – a metabolic lens on lupus pathogenesis.

Published in:

Central European Journal of Immunology, 2025, v. 50, n. 1, p. 1, doi. 10.5114/ceji.2025.151334

By:

Radzikowska, Urszula;
Tynecka, Marlena;
Eljaszewicz, Andrzej

Publication type:

Article

Aberrant glucose metabolism drives dysfunction of CD4<sup>+</sup> T cells in systemic lupus erythematosus and disease flares.

Published in:

Central European Journal of Immunology, 2025, v. 50, n. 1, p. 13, doi. 10.5114/ceji.2025.149252

By:

Jin, Lu;
Ding, Meng;
Cui, Shaoxin;
Yang, Lin;
Zhao, Jinwen;
He, Jingjing;
Wang, Xiaoping;
Chang, Fei;
Liu, Xue;
Wang, Qun;
Jin, Hongtao;
Ma, Jun;
Liu, Aijing

Publication type:

Article

Acute PM2.5 Exposure in Distinct NSCLC Cell Lines Reveals Strong Oxidative Stress and Therapy Resistance Signatures Through Transcriptomic Analysis.

Published in:

Toxics, 2025, v. 13, n. 6, p. 484, doi. 10.3390/toxics13060484

By:

Panya, Aussara;
Thongyim, Saruda;
Sattayawat, Pachara;
Inwongwan, Sahutchai

Publication type:

Article

Metabolomic Profiling Reveals PGPR-Driven Drought Tolerance in Contrasting Brassica juncea Genotypes.

Published in:

Metabolites (2218-1989), 2025, v. 15, n. 6, p. 416, doi. 10.3390/metabo15060416

By:

Sheoran, Asha Rani;
Lakra, Nita;
Saharan, Baljeet Singh;
Luhach, Annu;
Ahlawat, Yogesh K.;
Porcel, Rosa;
Mulet, Jose M.;
Singh, Prabhakar

Publication type:

Article

A Systems Hypothesis of Lipopolysaccharide-Induced Vitamin Transport Suppression and Metabolic Reprogramming in Autism Spectrum Disorders: An Open Call for Validation and Therapeutic Translation.

Published in:

Metabolites (2218-1989), 2025, v. 15, n. 6, p. 399, doi. 10.3390/metabo15060399

By:

Dervishi, Albion

Publication type:

Article

Exceptional Heme Tolerance in Serratia plymuthica : Proteomic Insights into Oxidative Stress Adaptation in the Aedes aegypti Midgut.

Published in:

Life (2075-1729), 2025, v. 15, n. 6, p. 950, doi. 10.3390/life15060950

By:

Machado, Sâmella da Hora;
Rodrigues, Rívea Cristina Custódio;
Bertonceli, Maria Aparecida Aride;
Gaio, Analiz de Oliveira;
Petroceli-Mota, Gabriela;
Reis, Ricardo de Souza;
Berbert-Molina, Marília Amorim;
Silveira, Vanildo;
Lemos, Francisco José Alves

Publication type:

Article

Developmental immune network of airway lymphocytes and innate immune cells in patients with stable COPD.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1614655

By:

Liu, Lanlan;
Zhou, Mei;
Sun, Shengwen;
Chen, Long;
Li, Dehu;
Lv, Jiaxi;
Cheng, Rui;
Zhang, Jianchu;
Wu, Jianghua;
Xiong, Xianzhi

Publication type:

Article

Lactylation in tumor: mechanisms and therapeutic potentials.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1609596

By:

Wang, Dandan;
Rong, Hao;
Ma, Ke;
Peng, Jun

Publication type:

Article

SLC31A1 loss depletes mitochondrial copper and promotes cardiac fibrosis Free.

Published in:

European Heart Journal, 2025, v. 46, n. 25, p. 2458, doi. 10.1093/eurheartj/ehaf130

By:

Tu, Bin;
Song, Kai;
Zhou, Ze-Yu;
Lin, Li-Chan;
Liu, Zhi-Yan;
Sun, He;
Zhou, Yang;
Sha, Ji-Ming;
Shi, Yan;
Yang, Jing-Jing;
Zhang, Ye;
Zhao, Jian-Yuan;
Tao, Hui

Publication type:

Article