Works matching DE "METABOLIC reprogramming"

Results: 1197

Targeting amino acid in tumor therapy.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1582116

By:

Ge, Mingpai;
Xu, Yuan;
Cui, Lu;
Huang, Enyuan;
Liu, Zhaorui;
Yin, Kai

Publication type:

Article

Integrated transcriptomics and machine learning reveal REN as a dual regulator of tumor stemness and NK cell evasion in Wilms tumor progression.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1612987

By:

Cao, Qingfei;
Li, Junyi;
Zou, Yunfei;
Xu, Changwen;
Tang, Huihui;
Chen, Meixue

Publication type:

Article

Navigating the role of protein lactylation in prostate cancer and its implications for immunotherapy.

Published in:

Journal of Cancer, 2025, v. 16, n. 8, p. 2706, doi. 10.7150/jca.114137

By:

Dongzhang Li;
Kaifeng Wang;
Guantao Lou;
Wangjian Li;
Quan Ma;
Yu'e Liu;
Yongliang Chen

Publication type:

Article

Mechanistic insights into hypoxia‐induced metabolic reprogramming in colorectal cancer through genome‐scale modeling.

Published in:

Biotechnology Progress, 2025, v. 41, n. 3, p. 1, doi. 10.1002/btpr.70002

By:

Omer, Sonal;
Sridhar, Subasree;
Karunagaran, D.;
Suraishkumar, G. K.

Publication type:

Article

Research advances in the study of traditional Chinese medicine formula granules on signaling pathway-mediated disease mechanisms.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1609211

By:

Gu, Zhuo-Xu;
Wang, Zhong-Hao;
Zhang, Xian-Quan;
Zhou, Guang-Hui;
Liang, Gui-Hong;
Zeng, Ling-Feng;
Liu, Jun

Publication type:

Article

Gestational saccharin consumption disrupts gut-brain axis glucose homeostasis control in adolescent offspring rats in a sex-dependent manner.

Published in:

Biology of Sex Differences, 2025, v. 16, n. 1, p. 1, doi. 10.1186/s13293-025-00724-5

By:

Pacheco-Sánchez, Beatriz;
Melgar-Locatelli, Sonia;
López-Merchán, Raquel;
Benítez-Marín, María José;
Blasco-Alonso, Marta;
González-Mesa, Ernesto;
Tovar, Rubén;
Rubio, Pablo;
Suárez, Juan;
Sanjuan, Carlos;
de Fonseca, Fernando Rodríguez;
Alén, Francisco;
de Ceglia, Marialuisa;
Rivera, Patricia

Publication type:

Article

Enhanced resistance to Listeria infection in mice surviving sepsis: the role of lipid metabolism and myeloid cell reprogramming.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1588987

By:

Watanabe, Haruki;
Song, Tengfei;
Choi, Jaewoo;
Lee, Moses;
Choi, Kwangmin;
Kim, Junhwan;
Sherry, Barbara;
Diamond, Betty;
Zou, Yong-Rui;
Son, Myoungsun

Publication type:

Article

Metabolic profiling of glioblastoma and identification of G0S2 as a metabolic target.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1572040

By:

Kang, Jianlei;
Xu, Yujie;
Zhao, Qitai;
Wang, Ying;
He, Zhenyan;
Xu, Xin

Publication type:

Article

The potential of ME1 in guiding immunotherapeutic strategies for ovarian cancer: insights from pan-cancer research.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1571842

By:

Wei, Jiahui;
Wang, Ming;
Xu, Shuiqing;
Tusufuhan, Paizigul;
Wu, Yumei

Publication type:

Article

Outer membrane vesicles derived from probiotic Escherichia coli Nissle 1917 promote metabolic remodeling and M1 polarization of RAW264.7 macrophages.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1501174

By:

Ma, DongXue;
Zhang, YuXin;
Zhang, Jia;
Shi, Jun;
Gao, ShanHu;
Long, Fei;
Wang, Xin;
Pu, XingYu;
Sun, Jiayao;
Liang, Shuang;
Cannon, Richard D.;
Villas-Boas, Silas;
Han, Ting-Li

Publication type:

Article

Aristolochic acid I orchestrates multi-organ carcinogenesis through apoptotic pathway in bladder, kidney, and liver cancers: a multi-omics dissection.

Published in:

Environmental Sciences Europe, 2025, v. 37, n. 1, p. 1, doi. 10.1186/s12302-025-01146-1

By:

Zhang, Bitian;
Leung, Ping-Chung;
Wong, Chun-Kwok;
Wang, Dongjie

Publication type:

Article

Exercise orchestrates systemic metabolic and neuroimmune homeostasis via the brain–muscle–liver axis to slow down aging and neurodegeneration: a narrative review.

Published in:

European Journal of Medical Research, 2025, v. 30, n. 1, p. 1, doi. 10.1186/s40001-025-02751-9

By:

Kong, Jianda;
Xie, Yingao;
Fan, Rao;
Wang, Qinglu;
Luo, Ying;
Dong, Panpan

Publication type:

Article

Multi-omics-Based Construction of ncRNA-Gene-Metabolite Networks Provides New Insights Into Metabolic Regulation Under Salt Stress in Rice.

Published in:

Rice (19398425), 2025, v. 18, n. 1, p. 1, doi. 10.1186/s12284-025-00811-6

By:

Tong, Haiyang;
Wang, Chao;
Han, Xiaoqian;
Sun, Qihao;
Luo, Enxi;
Yang, Chao;
Xu, Guo;
Ou, Xumin;
Li, Shixuan;
Zhang, Jianing;
Yang, Jun

Publication type:

Article

Lipid droplet accumulation in microglia and their potential roles.

Published in:

Lipids in Health & Disease, 2025, v. 24, n. 1, p. 1, doi. 10.1186/s12944-025-02633-3

By:

Li, Yunxia;
Zhao, Qi;
Wang, Yan;
Du, Wenyi;
Yang, Riyun;
Wu, Jian;
Li, Yi

Publication type:

Article

Activation of mechanosensitive ion channel Piezo1 linking metabolic reprogramming and pro-inflammatory responses in hepatocellular carcinoma.

Published in:

Cell Communication & Signaling, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12964-025-02289-7

By:

Mo, Juanfen;
Zhang, YuXuan;
Cao, Chenxi;
Zheng, WeiLi;
Zheng, Li;
Wang, Xiaoguang;
Wang, Shiyue;
Wu, Jiayuan;
Bao, Yi

Publication type:

Article

Single-cell multi-omics reveals that FABP1 + renal cell carcinoma drive tumor angiogenesis through the PLG-PLAT axis under fatty acid reprogramming.

Published in:

Molecular Cancer, 2025, v. 24, n. 1, p. 1, doi. 10.1186/s12943-025-02377-9

By:

Wang, Yiqiu;
Liang, Yingchun;
Li, Min;
Lu, Jiayi;
Zhou, Sian;
Yu, Yaoyu;
Yang, Changwei;
Hou, Xinhuang

Publication type:

Article

The role and mechanism of fatty acid oxidation in cancer drug resistance.

Published in:

Cell Death Discovery, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41420-025-02554-1

By:

Lei, Yun;
Cai, Shuang;
Zhang, Jia-Kui;
Ding, Si-Qi;
Zhang, Zhan-He;
Zhang, Chun-Dong;
Dai, Dong-Qiu;
Li, Yong-Shuang

Publication type:

Article

Phthalates unleashed: decoding ovarian carcinogenesis through multi-omics networks, single-cell insights, and molecular docking.

Published in:

Journal of Ovarian Research, 2025, v. 18, n. 1, p. 1, doi. 10.1186/s13048-025-01710-6

By:

Yang, Junchan;
Luo, Min;
Wang, Hongjun;
Huang, Jinfa

Publication type:

Article

ALDOC and PGK1 coordinately induce glucose metabolism reprogramming and promote development of colorectal cancer.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01252-z

By:

Huang, Liyong;
Tong, Yixin;
Li, Xu;
Wang, Wei;
Wang, Zhen;
Chen, Bingchen;
E., Jifu;
Zhou, Ruzhen;
Wang, Hantao;
He, Jinghu

Publication type:

Article

Dietary Supplementation of Lactobacillus reuteri Modulates Amino Acid Metabolism and Extracellular Matrix in the Gut–Liver Axis of Weaned Piglets.

Published in:

Animals (2076-2615), 2025, v. 15, n. 11, p. 1567, doi. 10.3390/ani15111567

By:

He, Yiyi;
Wei, Yangyang;
Ruan, Shihui;
Wu, Qiwen;
Xiong, Yunxia;
Wang, Li;
Jiang, Zongyong;
Xu, E;
Yi, Hongbo

Publication type:

Article

Lipid Metabolism Reprogramming in Tumor-Associated Macrophages Modulates Their Function in Primary Liver Cancers.

Published in:

Cancers, 2025, v. 17, n. 11, p. 1858, doi. 10.3390/cancers17111858

By:

Oliviero, Barbara;
Caretti, Anna;
Mondelli, Mario U.;
Mantovani, Stefania

Publication type:

Article

Lymphatic Metastasis of Esophageal Squamous Cell Carcinoma: The Role of NRF2 and Therapeutic Strategies.

Published in:

Cancers, 2025, v. 17, n. 11, p. 1853, doi. 10.3390/cancers17111853

By:

Li, Yahui;
Ladd, Zachary;
Xiong, Zhaohui;
Bui-Linh, Candice;
Paiboonrungruang, Chorlada;
Subramaniyan, Boopathi;
Li, Huan;
Wang, Haining;
Balch, Curt;
Shersher, David D.;
Spitz, Francis;
Chen, Xiaoxin

Publication type:

Article

Cellular Heterogeneity and IL-17 Pathway Dynamics Reveal Insights into the Transition from Ulcerative Colitis to Colorectal Cancer Through scRNA-Seq Analysis.

Published in:

Journal of Inflammation Research, 2025, v. 18, p. 6927, doi. 10.2147/JIR.S505313

By:

Li, Yaxian;
Sun, Ruochuan;
Wang, Xiaodong;
Ma, Mengdi;
Wang, Huizhen;
Yang, Bo;
Lu, Yida;
Li, Yongxiang

Publication type:

Article

Brief Weekly Magnetic Field Exposure Enhances Avian Oxidative Muscle Character During Embryonic Development.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 11, p. 5423, doi. 10.3390/ijms26115423

By:

Yap, Jasmine Lye Yee;
Wu, Kwan Yu;
Tai, Yee Kit;
Fong, Charlene Hui Hua;
Manazir, Neha;
Paul, Anisha Praiselin;
Yeo, Olivia;
Franco-Obregón, Alfredo

Publication type:

Article

PBX3-HMGCR Axis Promotes Hepatocellular Carcinoma Progression Through Enhancing De Novo Cholesterol Biosynthesis.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 11, p. 5210, doi. 10.3390/ijms26115210

By:

Zhang, Xia;
Qiu, Li;
Zhang, Lei;
Li, Wenfang;
Xiang, Debing;
Wang, Jian;
Wu, Shourong;
Kasim, Vivi

Publication type:

Article

Clinical Significance of NUDT1 (MTH1) Across Cancer Types.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 11, p. 5137, doi. 10.3390/ijms26115137

By:

Misiak, Radosław;
Białkowski, Karol;
Dondajewska, Ewelina

Publication type:

Article

HIF-1α-Mediated Disruption of Cellular Junctions: The Impact of Hypoxia on the Tumor Microenvironment and Invasion.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 11, p. 5101, doi. 10.3390/ijms26115101

By:

Springer, Michael;
Burakgazi, Zeynep Aydin;
Domukhovska, Anastasiia;
Nafchi, Ben;
Beary, Michael C.;
Acquisto, Arielle;
Acquisto, Juliette;
Komarov, Vladyslav;
Jensen, Madison;
Gulledge, Brandon;
Poplavskyi, Maksym;
Uddin, Md Gias;
Rayan, Gamal;
Zucker, Shoshanna N.

Publication type:

Article

Role of Ischemia/Reperfusion and Oxidative Stress in Shock State.

Published in:

Cells (2073-4409), 2025, v. 14, n. 11, p. 808, doi. 10.3390/cells14110808

By:

Vázquez-Galán, Yarielis Ivette;
Guzmán-Silahua, Sandra;
Trujillo-Rangel, Walter Ángel;
Rodríguez-Lara, Simón Quetzalcoatl

Publication type:

Article

Metabolic Reprogramming Triggered by Fluoride in U-87 Glioblastoma Cells: Implications for Tumor Progression?

Published in:

Cells (2073-4409), 2025, v. 14, n. 11, p. 800, doi. 10.3390/cells14110800

By:

Żwierełło, Wojciech;
Maruszewska, Agnieszka;
Skórka-Majewicz, Marta;
Wszołek, Agata;
Gutowska, Izabela

Publication type:

Article

Mitochondrial Dysfunction: The Silent Catalyst of Kidney Disease Progression.

Published in:

Cells (2073-4409), 2025, v. 14, n. 11, p. 794, doi. 10.3390/cells14110794

By:

Pavlović, Nikola;
Križanac, Marinela;
Kumrić, Marko;
Vukojević, Katarina;
Božić, Joško

Publication type:

Article

Systematic proteomic and small RNA profiling of extracellular vesicles from cattle infected with a naturally occurring buparvaquone-resistant strain of Theileria annulata and from uninfected controls.

Published in:

Parasites & Vectors, 2025, v. 18, n. 1, p. 1, doi. 10.1186/s13071-025-06834-8

By:

Chai, Yijun;
Che, Jin;
Wang, Jinming;
Guan, Guiquan;
Yin, Hong

Publication type:

Article

Branched-chain amino acid and cancer: metabolism, immune microenvironment and therapeutic targets.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06664-3

By:

Xiong, Hao;
Liu, Ruiqi;
Xu, Keke;
Chen, Xiaoyan;
Huang, Luanluan;
Shou, Yiyi;
Huang, Yumei;
Sheng, Hailong;
Lu, Yanwei;
Zhang, Haibo

Publication type:

Article

Targeting the leptin receptor promotes MDA-MB-231 cells' metabolic reprogramming and malignancy: the role of extracellular vesicles derived from obese adipose tissue.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1568524

By:

Encarnação, Carol Costa;
Amorim, Carolinne Souza;
Franco, Victor Aguiar;
Botelho, Luiz Gabriel Xavier;
dos Santos, Ronan Christian Machado;
Ramos-Andrade, Isadora;
Kraemer-Aguiar, Luiz Guilherme;
Barja-Fidalgo, Christina;
Moraes, João Alfredo;
Renovato-Martins, Mariana

Publication type:

Article

Perturbation-response analysis of in silico metabolic dynamics revealed hard-coded responsiveness in the cofactors and network sparsity.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.98800

By:

Yusuke Himeoka;
Chikara Furusawa

Publication type:

Article

Energy metabolism: An emerging therapeutic frontier in liver fibrosis.

Published in:

Annals of Hepatology: Official Journal of the Mexican Association of Hepatology, 2025, v. 30, n. 1, p. 1, doi. 10.1016/j.aohep.2025.101896

By:

Irshad, Iram;
Alqahtani, Saleh A.;
Kenichi Ikejima;
Ming-Lung Yu;
Romero-Gomez, Manuel;
Eslam, Mohammed

Publication type:

Article

脂代谢异常在宫颈癌转移中作用的研究进展.

Published in:

Progress in Modern Biomedicine, 2025, v. 25, n. 7, p. 1271, doi. 10.13241/j.cnki.pmb.2025.07.019

By:

白双;
王怡;
孙云燕

Publication type:

Article

Glycolytic control proteins in urinary extracellular vesicles are elevated during kidney transplant T cell-mediated rejection.

Published in:

BMC Nephrology, 2025, v. 26, n. 1, p. 1, doi. 10.1186/s12882-025-04196-y

By:

Leung, P.Y.M.;
Graver, A.S.;
Katerelos, M.;
Skene, A.;
Whitlam, J.B.;
Power, D.A.;
Mount, P.F.

Publication type:

Article

Ferroptosis-related LncRNAs in diseases.

Published in:

BMC Biology, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12915-025-02268-x

By:

Zhou, Wu;
Thiery, Jean Paul

Publication type:

Article

Glutamate transporter SLC1A6 promotes resistance to immunotherapy in cancer.

Published in:

Cancer Immunology, Immunotherapy, 2025, v. 74, n. 8, p. 1, doi. 10.1007/s00262-025-04074-4

By:

Li, Chenchen;
Lin, Yi;
Zheng, Haoran;
Zeng, Hengda;
Xu, Longhao;
Wu, Daqin;
Lao, Jianwen;
Cai, Peicong;
Liang, Shuai;
Wang, Chunhui;
Lin, Tianxin;
Zhong, Wenlong

Publication type:

Article

Combination strategies of gut microbiota in cancer therapy through metabolic reprogramming and immune remodeling.

Published in:

Cell Communication & Signaling, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12964-025-02275-z

By:

Wang, Lixuan;
Jiang, Weibo;
Yang, Manshi;
Danzeng, Quezhu;
Liu, Shiyu;
Cui, Mengying

Publication type:

Article

VSIG4 Promotes Tumour‐Associated Macrophage M2 Polarization and Immune Escape in Colorectal Cancer via Fatty Acid Oxidation Pathway.

Published in:

Clinical & Translational Medicine, 2025, v. 15, n. 5, p. 1, doi. 10.1002/ctm2.70340

By:

Liu, Jiafeng;
Zhang, WenXin;
Chen, Lu;
Wang, Xinhai;
Mao, Xiang;
Wu, Zimei;
Shi, Huanying;
Qi, Huijie;
Chen, Li;
Huang, Yuxin;
Li, Jiyifan;
Zhong, Mingkang;
Shi, Xiaojin;
Li, Qunyi;
Wang, Tianxiao

Publication type:

Article

Biological and prognostic insights into the prostaglandin D2 signaling axis in lung adenocarcinoma.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1562261

By:

Liu, Qiang;
Chen, Huiguo;
Tang, Dongfang;
Zhang, Huibiao;
Chen, Shaogeng;
Meng, Yiran;
Zheng, Boying;
Liu, Fei;
Zhou, Jing;
Zhang, Wen

Publication type:

Article

Single-cell and bulk transcriptome analyses reveal elevated amino acid metabolism promoting tumor-directed immune evasion in colorectal cancer.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1575829

By:

Sun, Tianyue;
Chen, Yan;
Chen, Ying-Xuan

Publication type:

Article

Metabolic profiles in laryngeal cancer defined two distinct molecular subtypes with divergent prognoses.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1512502

By:

Zheng, Dan;
Pu, Xuan;
Deng, XuHui;
Liu, Cui;
Li, SiJun

Publication type:

Article

TFAM通过调节代谢重编程对卵巢癌细胞化疗耐药的影响及其机制研究.

Published in:

Cancer Research on Prevention & Treatment, 2025, v. 52, n. 5, p. 374, doi. 10.3971/j.issn.1000-8578.2025.24.1072

By:

范玲玲;
热孜婉古丽·吾布力;
卢玲岚;
韩莉莉

Publication type:

Article

Hematopoietic stem and progenitor cells fine-tuning the "sweet" of trained immunity.

Published in:

Journal of Leukocyte Biology, 2025, v. 117, n. 5, p. 1, doi. 10.1093/jleuko/qiaf043

By:

Li, Jiawei;
Wang, Hui;
Xia, Sheng

Publication type:

Article

Metabolic reprogramming and therapeutic targeting in non-small cell lung cancer: emerging insights beyond the Warburg effect.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1564226

By:

Cai, Hong;
Zhang, Feng;
Xu, Fang;
Yang, Chunhui

Publication type:

Article

Mechanism and application of lactylation in cancers.

Published in:

Cell & Bioscience, 2025, v. 15, n. 1, p. 1, doi. 10.1186/s13578-025-01415-9

By:

Wang, Jiewen;
Peng, Mingjing;
Oyang, Linda;
Shen, Mengzhou;
Li, Shizhen;
Jiang, Xianjie;
Ren, Zongyao;
Peng, Qiu;
Xu, Xuemeng;
Tan, Shiming;
Xia, Longzheng;
Yang, Wenjuan;
Li, Haofan;
Wu, Nayiyuan;
Tang, Yanyan;
Lin, Jinguan;
Liao, Qianjin;
Han, Yaqian;
Zhou, Yujuan

Publication type:

Article

Multiple roles of mitochondria in tumorigenesis and treatment: from mechanistic insights to emerging therapeutic strategies.

Published in:

Oncologie (De Gruyter), 2025, v. 27, n. 3, p. 343, doi. 10.1515/oncologie-2024-0596

By:

Zhang, Min;
Yang, Yuchen;
Wu, Jiacheng;
Sun, Qian

Publication type:

Article

Salivary gamma-glutamyltransferase activity as an indicator of redox homeostasis in breast cancer.

Published in:

Oncologie (De Gruyter), 2025, v. 27, n. 3, p. 381, doi. 10.1515/oncologie-2025-0065

By:

Dyachenko, Elena I.;
Sarf, Elena A.;
Bel'skaya, Lyudmila V.

Publication type:

Article