Works matching DE "MET receptor"

Results: 367

Single‐Cell Transcriptomic Analysis Reveals an Aggressive Basal‐Like Tumor Cell Subpopulation Associated With Poor Prognosis in Intrahepatic Cholangiocarcinoma.

Published in:

Journal of Gastroenterology & Hepatology, 2025, v. 40, n. 5, p. 1263, doi. 10.1111/jgh.16915

By:

Liao, Changyi;
Zhang, Yuting;
Yang, Jing;
Wang, Shuo;
Li, Zhijuan;
Chen, Shuling;
Xie, Yubin;
Xu, Lixia;
Peng, Sui;
Zeng, Xuezhen;
Kuang, Ming;
Xiang, Bangde;
Sun, Kaiyu;
Zhao, Xiao

Publication type:

Article

卡博替尼治疗肝癌的多靶点作用及其研究进展.

Published in:

Evaluation & Analysis of Drug-Use in Hospitals of China / Zhongguo Yiyuan Yongyao Pingjia yu Fenxi, 2025, v. 25, n. 3, p. 376, doi. 10.14009/j.issn.1672-2124.2025.03.026

By:

王佩佩

Publication type:

Article

Mutation responsible for the mouse pygmy phenotype in the developmentally regulated factor HMGI-C.

Published in:

Nature, 1995, v. 376, n. 6543, p. 771, doi. 10.1038/376771a0

By:

Zhou, Xianjin;
Benson, Kathleen F.

Publication type:

Article

Essential role for the c-met receptor in the migration of myogenic precursor ...

Published in:

Nature, 1995, v. 376, n. 6543, p. 768, doi. 10.1038/376768a0

By:

Bladt, Friedham;
Riethmacher, Dieter

Publication type:

Article

Immunohistochemical Expression of Hepatocyte Growth Factor Receptor and Epidermal Growth Factor Receptor in Serous Ovarian Tumors.

Published in:

Zagazig University Medical Journal, 2025, v. 31, n. 3, p. 1197, doi. 10.21608/zumj.2025.350021.3777

By:

Mohamed Elarini, Raghda Mahdi;
Nour Elden, Eman Taher;
Mohamed, Reham Sameh;
Said, Nelly Mohamed

Publication type:

Article

Conserved regulatory motifs in the juxtamembrane domain and kinase N-lobe revealed through deep mutational scanning of the MET receptor tyrosine kinase domain.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.91619

By:

Estevam, Gabriella O.;
Linossi, Edmond M.;
Macdonald, Christian B.;
Espinoza, Carla A.;
Michaud, Jennifer M.;
Coyote-Maestas, Willow;
Collisson, Eric A.;
Jura, Natalia;
Fraser, James S.

Publication type:

Article

A case of cabozantinib‐induced pyoderma gangrenosum‐like ulceration.

Published in:

Australasian Journal of Dermatology, 2023, v. 64, n. 1, p. 154, doi. 10.1111/ajd.13944

By:

Matsudate, Yoshihiro;
Ninomiya, Iku;
Sadamoto, Yasushi

Publication type:

Article

Type II phosphatidylinositol 4-kinases promote Listeria monocytogenes entry into target cells.

Published in:

Cellular Microbiology, 2007, v. 9, n. 10, p. 2381, doi. 10.1111/j.1462-5822.2007.00967.x

By:

Pizarro-Cerdá, Javier;
Payrastre, Bernard;
Ying-Jie Wang;
Veiga, Esteban;
Yin, Helen L.;
Cossart, Pascale

Publication type:

Article

MET overexpression and gene amplification in NSCLC: a clinical perspective.

Published in:

Lung Cancer: Targets & Therapy, 2013, v. 4, p. 15, doi. 10.2147/LCTT.S35168

By:

Landi, Lorenza;
Minuti, Gabriele;
D'Incecco, Armida;
Salvini, Jessica;
Cappuzzo, Federico

Publication type:

Article

Regulation of MET receptor tyrosine kinase signaling by suppressor of cytokine signaling 1 in hepatocellular carcinoma.

Published in:

Oncogene, 2015, v. 34, n. 46, p. 5718, doi. 10.1038/onc.2015.20

By:

Gui, Y;
Yeganeh, M;
Donates, Y-C;
Tobelaim, W-S;
Chababi, W;
Mayhue, M;
Yoshimura, A;
Ramanathan, S;
Saucier, C;
Ilangumaran, S

Publication type:

Article

Targeting the oncogenic Met receptor by antibodies and gene therapy.

Published in:

Oncogene, 2015, v. 34, n. 15, p. 1883, doi. 10.1038/onc.2014.142

By:

Vigna, E;
Comoglio, P M

Publication type:

Article

Effective inhibition of c-MET-mediated signaling, growth and migration of ovarian cancer cells is influenced by the ovarian tissue microenvironment.

Published in:

Oncogene, 2015, v. 34, n. 2, p. 144, doi. 10.1038/onc.2013.539

By:

Kwon, Y;
Smith, B D;
Zhou, Y;
Kaufman, M D;
Godwin, A K

Publication type:

Article

Phosphoglycerate kinase 1 acts as a cargo adaptor to promote EGFR transport to the lysosome.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-45443-4

By:

Chu, Shao-Ling;
Huang, Jia-Rong;
Chang, Yu-Tzu;
Yao, Shu-Yun;
Yang, Jia-Shu;
Hsu, Victor W.;
Hsu, Jia-Wei

Publication type:

Article

Circular RNA encoded MET variant promotes glioblastoma tumorigenesis.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-40212-1

By:

Zhong, Jian;
Wu, Xujia;
Gao, Yixin;
Chen, Junju;
Zhang, Maolei;
Zhou, Huangkai;
Yang, Jia;
Xiao, Feizhe;
Yang, Xuesong;
Huang, Nunu;
Qi, Haoyue;
Wang, Xiuxing;
Bai, Fan;
Shi, Yu;
Zhang, Nu

Publication type:

Article

MET fusions and splicing variants is a strong adverse prognostic factor in astrocytoma, isocitrate dehydrogenase mutant.

Published in:

Brain Pathology, 2024, v. 34, n. 3, p. 1, doi. 10.1111/bpa.13198

By:

Liu, Lingyu;
Zhang, Ke‐Nan;
Zhao, Zheng;
Li, Guanzhang;
Chai, Rui‐Chao;
Li, Zhuoqun;
Liu, Xing;
Chen, Jing;
Jiang, Tao

Publication type:

Article

The hepatocyte epidermal growth factor receptor (EGFR) pathway regulates the cellular interactome within the liver fibrotic niche.

Published in:

Journal of Pathology, 2024, v. 263, p. 482, doi. 10.1002/path.6299

By:

Gonzalez‐Sanchez, Ester;
Vaquero, Javier;
Caballero‐Diaz, Daniel;
Grzelak, Jan;
Fusté, Noel P;
Bertran, Esther;
Amengual, Josep;
Garcia‐Saez, Juan;
Martín‐Mur, Beatriz;
Gut, Marta;
Esteve‐Codina, Anna;
Alay, Ania;
Coulouarn, Cedric;
Calero‐Perez, Silvia;
Valdecantos, Pilar;
Valverde, Angela M;
Sánchez, Aránzazu;
Herrera, Blanca;
Fabregat, Isabel

Publication type:

Article

PKC controls HGF-dependent c-Met traffic, signalling and cell migration.

Published in:

EMBO Journal, 2004, v. 23, n. 19, p. 3721, doi. 10.1038/sj.emboj.7600396

By:

Kermorgant, Stéphanie;
Zicha, Daniel;
Parker, Peter J.

Publication type:

Article

Exhaled phospholipid transfer protein and hepatocyte growth factor receptor in lung adenocarcinoma.

Published in:

Respiratory Research, 2022, v. 23, n. 1, p. 1, doi. 10.1186/s12931-022-02302-4

By:

Andreasson, Jesper;
Bodén, Embla;
Fakhro, Mohammed;
von Wachter, Camilla;
Olm, Franziska;
Malmsjö, Malin;
Hallgren, Oskar;
Lindstedt, Sandra

Publication type:

Article

Liquid biopsy proteomics of uveal melanoma reveals biomarkers associated with metastatic risk.

Published in:

2021

By:

Velez, Gabriel;
Nguyen, Huy V.;
Chemudupati, Teja;
Ludwig, Cassie A.;
Toral, Marcus;
Reddy, Sunil;
Mruthyunjaya, Prithvi;
Mahajan, Vinit B.

Publication type:

Letter

Systems modelling of the EGFR-PYK2-c-Met interaction network predicts and prioritizes synergistic drug combinations for triple-negative breast cancer.

Published in:

PLoS Computational Biology, 2018, v. 14, n. 6, p. 1, doi. 10.1371/journal.pcbi.1006192

By:

Shin, Sung-Young;
Müller, Anna-Katharina;
Verma, Nandini;
Lev, Sima;
Nguyen, Lan K.

Publication type:

Article

The role of ADAM17 during liver damage.

Published in:

Biological Chemistry, 2021, v. 402, n. 9, p. 1115, doi. 10.1515/hsz-2021-0149

By:

Al-Salihi, Mazin;
Bornikoel, Anna;
Zhuang, Yuan;
Stachura, Pawel;
Scheller, Jürgen;
Lang, Karl S.;
Lang, Philipp A.

Publication type:

Article

Pseudo-active sites of protease domains: HGF/Met and Sonic hedgehog signaling in cancer.

Published in:

Biological Chemistry, 2010, v. 391, n. 8, p. 881, doi. 10.1515/BC.2010.098

By:

Maun, Henry R.;
Kirchhofer, Daniel;
Lazarus, Robert A.

Publication type:

Article

Expression of the c-Met Proto-Oncogene and Integrin α5β1 in Human Gastric Cardia Adenocarcinoma.

Published in:

Bioscience, Biotechnology & Biochemistry, 2012, v. 76, n. 8, p. 1471, doi. 10.1271/bbb.120132

By:

Fusheng CHI;
Da FU;
Xiaoping ZHAN;
Zhongwei LV;
Zhesheng WANG

Publication type:

Article

An auxiliary binding interface of SHIP2-SH2 for Y292-phosphorylated FcγRIIB reveals diverse recognition mechanisms for tyrosine-phosphorylated receptors involved in different cell signaling pathways.

Published in:

Analytical & Bioanalytical Chemistry, 2022, v. 414, n. 1, p. 497, doi. 10.1007/s00216-021-03373-w

By:

Wang, Zi;
Zhou, Heng;
Yue, Xiali;
Zhu, Jiang;
Yang, Yunhuang;
Liu, Maili

Publication type:

Article

Functionalized Biomimetic Magnetic Nanoparticles as Effective Nanocarriers for Targeted Chemotherapy.

Published in:

Particle & Particle Systems Characterization, 2019, v. 36, n. 6, p. N.PAG, doi. 10.1002/ppsc.201900057

By:

Peigneux, Ana;
Oltolina, Francesca;
Colangelo, Donato;
Iglesias, Guillermo R.;
Delgado, Angel V.;
Prat, Maria;
Jimenez‐Lopez, Concepcion

Publication type:

Article

High levels of c-Met is associated with poor prognosis in glioblastoma.

Published in:

Journal of Neuro-Oncology, 2015, v. 122, n. 3, p. 517, doi. 10.1007/s11060-015-1723-3

By:

Petterson, Stine;
Dahlrot, Rikke;
Hermansen, Simon;
K. A. Munthe, Sune;
Gundesen, Michael;
Wohlleben, Helle;
Rasmussen, Tine;
Beier, Christoph;
Hansen, Steinbjørn;
Kristensen, Bjarne

Publication type:

Article

Gain of chromosome 7 by chromogenic in situ hybridization (CISH) in chordomas is correlated to c-MET expression.

Published in:

Journal of Neuro-Oncology, 2011, v. 101, n. 2, p. 199, doi. 10.1007/s11060-010-0250-5

By:

Walter, Beatriz;
Begnami, Maria;
Valera, Vladimir;
Santi, Mariarita;
Rushing, Elisabeth;
Quezado, Martha

Publication type:

Article

c-Met-targeted RNA interference inhibits growth and metastasis of glioma U251 cells in vitro.

Published in:

Journal of Neuro-Oncology, 2009, v. 93, n. 2, p. 183, doi. 10.1007/s11060-008-9772-5

By:

Sheng-Hua Chu;
Dong-Fu Feng;
Hong Zhang;
Er-Tao Chen;
Zhi-Xin Duan;
Xue-Yuan Li;
Jia Li;
Yan-Bin Ma;
Zhi-An Zhu;
Jian-Hua Qiu

Publication type:

Article

Targeting c- Met in Cancer by Micro RNAs: Potential Therapeutic Applications in Hepatocellular Carcinoma.

Published in:

Drug Development Research, 2015, v. 76, n. 7, p. 357, doi. 10.1002/ddr.21274

By:

Karagonlar, Zeynep F.;
Korhan, Peyda;
Atabey, Neşe

Publication type:

Article

MET gene alterations predict poor survival following chemotherapy in patients with advanced cancer.

Published in:

Pathology & Oncology Research, 2022, p. 01, doi. 10.3389/pore.2022.1610697

By:

Jihoon Ko;
Jaeyun Jung;
Seung Tae Kim;
Jung Yong Hong;
Sehhoon Park;
Joon Oh Park;
Young Suk Park;
Ho Yeong Lim;
Soomin Ahn;
Kyoung-Mee Kim;
Won Ki Kang;
Jeeyun Lee

Publication type:

Article

A Drug–Drug Multicomponent Crystal of Metformin and Dobesilate: Crystal Structure Analysis and Hygroscopicity Property.

Published in:

Molecules, 2022, v. 27, n. 11, p. 3472, doi. 10.3390/molecules27113472

By:

Jiang, Lan;
Hu, Xiangnan;
Cai, Linhong

Publication type:

Article

Studying the Binding Modes of Novel 2-Aminopyridine Derivatives as Effective and Selective c-Met Kinase Type 1 Inhibitors Using Molecular Modeling Approaches.

Published in:

Molecules, 2021, v. 26, n. 1, p. 52, doi. 10.3390/molecules26010052

By:

Ye, Qianwen;
Fu, Chenggong;
Li, Jiazhong;
Chelli, Riccardo

Publication type:

Article

Research Progress of Small Molecule VEGFR/c-Met Inhibitors as Anticancer Agents (2016–Present).

Published in:

Molecules, 2020, v. 25, n. 11, p. 2666, doi. 10.3390/molecules25112666

By:

Zhang, Qian;
Zheng, Pengwu;
Zhu, Wufu;
Muñoz-Torrero, Diego;
Pascual-Teresa, Beatriz De

Publication type:

Article

Ochratoxin A activates opposing c-MET/PI3K/Akt and MAPK/ERK 1-2 pathways in human proximal tubule HK-2 cells.

Published in:

Archives of Toxicology, 2015, v. 89, n. 8, p. 1313, doi. 10.1007/s00204-014-1311-x

By:

Özcan, Zeynep;
Gül, Gizem;
Yaman, Ibrahim

Publication type:

Article

Activation of the Met Receptor by Cell Attachment Induces and Sustains Hepatocellular Carcinomas...

Published in:

Journal of Cell Biology, 2001, v. 153, n. 5, p. 1023, doi. 10.1083/jcb.153.5.1023

By:

Rong Wang;
Ferrell, Linda D.;
Faouzi, Saadia;
Maher, Jacquelyn J.;
Bishop, J. Michael

Publication type:

Article

Combined Expression of HGFR with Her2/neu, EGFR, IGF1R, Mucin-1 and Integrin α2β1 Is Associated with Aggressive Epithelial Ovarian Cancer.

Published in:

Biomedicines, 2022, v. 10, n. 11, p. 2694, doi. 10.3390/biomedicines10112694

By:

Czogalla, Bastian;
Dötzer, Katharina;
Sigrüner, Nicole;
von Koch, Franz Edler;
Brambs, Christine E.;
Anthuber, Sabine;
Frangini, Sergio;
Burges, Alexander;
Werner, Jens;
Mahner, Sven;
Mayer, Barbara

Publication type:

Article

Integrin α2β1 Represents a Prognostic and Predictive Biomarker in Primary Ovarian Cancer.

Published in:

Biomedicines, 2021, v. 9, n. 3, p. 289, doi. 10.3390/biomedicines9030289

By:

Dötzer, Katharina;
Schlüter, Friederike;
Koch, Franz Edler von;
Brambs, Christine E.;
Anthuber, Sabine;
Frangini, Sergio;
Czogalla, Bastian;
Burges, Alexander;
Werner, Jens;
Mahner, Sven;
Mayer, Barbara;
Plotti, Francesco

Publication type:

Article

AXL and MET Tyrosine Kinase Receptors Co-Expression as a Potential Therapeutic Target in Malignant Pleural Mesothelioma.

Published in:

Journal of Personalized Medicine, 2022, v. 12, n. 12, p. 1993, doi. 10.3390/jpm12121993

By:

Zito Marino, Federica;
Della Corte, Carminia Maria;
Ciaramella, Vincenza;
Erra, Stefania;
Ronchi, Andrea;
Fiorelli, Alfonso;
Vicidomini, Giovanni;
Santini, Mario;
Scognamiglio, Giosuè;
Morgillo, Floriana;
Ciardiello, Fortunato;
Franco, Renato;
Accardo, Marina

Publication type:

Article

GLMN variants cause skin hyperpigmentation: a promising potential therapeutic target.

Published in:

British Journal of Dermatology, 2024, v. 191, n. 1, p. 11, doi. 10.1093/bjd/ljae149

By:

Cao, Qiaoyu;
Li, Ming

Publication type:

Article

A Hrs binding protein having a Src homology 3 domain is involved in intracellular degradation of growth factors and their receptors.

Published in:

Genes to Cells, 2000, v. 5, n. 1, p. 57, doi. 10.1046/j.1365-2443.2000.00303.x

By:

Takata, Hiroyuki;
Kato, Masaki;
Denda, Kimitoshi;
Kitamura, Naomi

Publication type:

Article

c-Met inhibition enhances chemosensitivity of human ovarian cancer cells.

Published in:

Clinical & Experimental Pharmacology & Physiology, 2017, v. 44, n. 1, p. 79, doi. 10.1111/1440-1681.12672

By:

Wang, Jing;
Cheng, Jian‐Xin

Publication type:

Article

Pathway specificity for Met signalling.

Published in:

Nature Cell Biology, 2001, v. 3, n. 7, p. E161, doi. 10.1038/35083116

By:

Comoglio, Paolo M.

Publication type:

Article

HDAC1–Smad3–mSin3A complex is required for Smad3-induced transcriptional inhibition of hepatocyte growth factor receptor in human lung cancers.

Published in:

Carcinogenesis, 2021, v. 42, n. 4, p. 587, doi. 10.1093/carcin/bgaa112

By:

Gui, Hao-Xin;
Peng, Jun;
Yang, Ze-Ping;
Chen, Lu-Yao;
Zeng, Hong;
Shao, Yu-Ting;
Mu, Xi;
Hao, Qian;
Yang, Yang;
An, Su;
Guo, Xiao-Xi;
Xu, Tian-Rui;
Liu, Ying

Publication type:

Article

Regulation of the MET oncogene: molecular mechanisms.

Published in:

Carcinogenesis, 2016, v. 37, n. 4, p. 345, doi. 10.1093/carcin/bgw015

By:

Zhang, Jack;
Babic, Andy

Publication type:

Article

Activation of PAX3-MET pathways due to miR-206 loss promotes gastric cancer metastasis.

Published in:

Carcinogenesis, 2015, v. 36, n. 3, p. 390, doi. 10.1093/carcin/bgv009

By:

Zhang, Lin;
Xia, Limin;
Zhao, Lina;
Chen, Zhangqian;
Shang, Xin;
Xin, Jing;
Liu, Muhan;
Guo, Xuegang;
Wu, Kaichun;
Pan, Yanglin;
Fan, Daiming

Publication type:

Article

Gab1 but not Grb2 mediates tumor progression in Met overexpressing colorectal cancer cells.

Published in:

Carcinogenesis, 2008, v. 29, n. 3, p. 647, doi. 10.1093/carcin/bgn009

By:

Isolde Seiden-Long;
Roya Navab;
Warren Shih;
Ming Li;
Jane Chow;
Chang Qi Zhu;
Nikolina Radulovich;
Caroline Saucier;
Ming-Sound Tsao

Publication type:

Article

Expression of c-Met Is Different along the Location and Associated with Lymph Node Metastasis of Head and Neck Carcinoma.

Published in:

Korean Journal of Pathology, 2012, v. 46, n. 6, p. 515, doi. 10.4132/KoreanJPathol.2012.46.6.515

By:

Ji-Young Choe;
Ji Yun Yun;
Soo-Jeong Nam;
Ji Eun Kim

Publication type:

Article

Design Some New Type-I c-met Inhibitors Based on Molecular Docking and Topomer CoMFA Research.

Published in:

Molecular Informatics, 2014, v. 33, n. 8, p. 536, doi. 10.1002/minf.201300118

By:

Tian, Yuanxin;
Shen, Yudong;
Zhang, Xianzuo;
Ye, Lianbao;
Li, Zhonghuang;
Liu, Zhong;
Zhang, Jiajie;
Wu, Shuguang

Publication type:

Article

Pharmacophore Mapping Approach for Drug Target Identification: A Chemical Synthesis and in Silico Study on Novel Thiadiazole Compounds.

Published in:

Journal of Clinical & Diagnostic Research, 2017, v. 11, n. 5, p. 1, doi. 10.7860/JCDR/2017/22761.9925

By:

MESHRAM, ROHAN J.;
BALADHYE, VIJAY B.;
GACCHE, RAJESH N.;
KARALE, BHAUSAHEB K.;
GAIKAR, RAJENDRA B.

Publication type:

Article

Identification of other Cellular Receptors for Edema Factor of Bacillus anthracis by Independent Inhibition of Protective Evidenced by Inhibition of Embryo Growth and Antigen Angiogenesis.

Published in:

Archives of Razi Institute, 2021, v. 76, n. 4, p. 847, doi. 10.22092/ari.2021.355959.1756

By:

Khandia, R.;
Pattnaik, B.;
Rajukumar, K.;
Pateriya, A. K.;
Puranik, N.;
Bhatia, S.;
Murugkar, H.

Publication type:

Article