Works matching DE "MENDELIAN randomization"

Results: 1631

The Inflammatory‐Immune Axis in Thyroid Disease: A Mendelian Randomization Study.

Published in:

International Journal of Endocrinology, 2025, v. 2025, p. 1, doi. 10.1155/ije/6644708

By:

Pan, Tao;
Fang, Zhihao;
Hui, Titi;
Wu, Xuanlin;
Hu, Xu;
You, Jiabin;
Liu, Chang;
Saleem, Suraiya

Publication type:

Article

Assessing the Protective Role of Cheese Consumption Against Type 2 Diabetes and Its Complications: A Mendelian Randomization Study.

Published in:

International Journal of Endocrinology, 2025, v. 2025, p. 1, doi. 10.1155/ije/8880270

By:

Weng, Shuwei;
Guo, Xin;
Ding, Chen;
Hu, Die;
Peng, Daoquan;
Merlotti, Daniela

Publication type:

Article

Targeted screening and single-cell analysis of genetic variants in melanoma using Mendelian randomization.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-03225-4

By:

Li, Shi;
Zhang, Kaijiong;
Zhang, Guiji;
Shi, Min;
Yin, Xing;
Wang, Bo

Publication type:

Article

Genetic evidence for causal relationships between vegetarian biomarkers and esophageal cancer risk.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-03200-z

By:

Liu, Xinqi;
Xu, Xu;
Jiang, Zhenglong;
Du, Ning;
Chen, Jiayang;
Chang, Jinyuan;
Liu, Lixing;
Feng, Li

Publication type:

Article

Associations between circulating metabolites and pca: a bidirectional two-sample Mendelian randomization study.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-03204-9

By:

Lv, Jing;
Deng, Yonghong

Publication type:

Article

Mediating factors between autoimmune thyroiditis and breast cancer: a bidirectional Mendelian randomization study.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-03206-7

By:

Xin, Pei;
Wang, Lei;
Chen, Xianyang;
Li, Huazhi;
Jiang, Nan

Publication type:

Article

Identification of biomarkers for Laryngeal squamous cell carcinoma through Mendelian randomization and integrated bioinformatics analysis.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-03114-w

By:

Zhang, Pengjian;
Chen, Weizhang;
Chen, Kai;
Ye, Yuanhang;
Wu, Weijun

Publication type:

Article

Bifidobacterium depletion promotes goiter via gut-thyroid axis: evidence from Mendelian randomization and experimental validation.

Published in:

Frontiers in Microbiology, 2025, p. 1, doi. 10.3389/fmicb.2025.1621167

By:

Liao, Wenyong;
Jiang, Yang;
Zhang, Jiwen;
Wu, Yinghao;
Yu, Xue;
Chen, Shaohong;
Liu, Haiyan;
Xiu, Linlin;
Zhong, Gansheng

Publication type:

Article

Exploration of the Relationship between Macrophage-Related Proteins and the Risk and Prognosis of Breast Cancer.

Published in:

Clinical Laboratory, 2025, v. 71, n. 7, p. 1334, doi. 10.7754/Clin.Lab.2025.241128

By:

Hong-Fang Ma;
Qi-Na He;
Yi Lu;
Jun Shen

Publication type:

Article

Gut Microbiota, Disorders of Gut-Brain Interaction and Psychiatric Disorders: a Mendelian Randomization Study.

Published in:

Clinical Laboratory, 2025, v. 71, n. 7, p. 1285, doi. 10.7754/Clin.Lab.2025.250107

By:

Zhenni Wang;
Haiyan Wang;
Ning Wang;
Xiaohui Qu;
Xiaofeng Mu;
Shaoyun Cheng

Publication type:

Article

Cross-tissue transcriptome-wide analysis reveals novel insights into thyroid cancer etiology.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-03194-8

By:

Zhu, Yue;
Luo, Yu;
Zhang, Yuye;
Wang, Yixuan;
Gu, Zhangqi;
Liu, Jinyan;
Qin, Ancheng;
Qian, Weifeng

Publication type:

Article

Expression and prognostic value of SEC13 across multiple tumour types and its association with the regulation by Pulsatilla chinensis: a multi-omics and Mendelian Randomization Study.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-03148-0

By:

Leng, Huaqing;
Luan, Xin;
Li, Ming

Publication type:

Article

Letter to the Editor Regarding "The Relationship and Mechanisms Between Body Mass Index and Autoimmune Hypothyroidism: Insights from Mendelian Randomization".

Published in:

2025

By:

Zhao, Ping;
Han, Qiuwan;
Qiu, Xu;
Zhao, Jian

Publication type:

Letter

Genetic insights into the effect of Metformin on psychiatry disorders.

Published in:

European Archives of Psychiatry & Clinical Neuroscience, 2025, v. 275, n. 5, p. 1465, doi. 10.1007/s00406-025-02039-3

By:

Zhou, Qin;
Du, Zhiqiang;
Lu, Rongrong;
Shen, Yuan;
Jiang, Ying;
Zhu, Haohao

Publication type:

Article

Mendelian randomization identifies proteins involved in neurodegenerative diseases.

Published in:

Brain: A Journal of Neurology, 2025, v. 148, n. 7, p. 2412, doi. 10.1093/brain/awaf018

By:

Belbasis, Lazaros;
Morris, Sam;
Duijn, Cornelia van;
Bennett, Derrick;
Walters, Robin

Publication type:

Article

Expectations for papers performing Mendelian randomization analyses.

Published in:

2025

By:

Williams, Scott M.;
Tang, Hua;
Cooper, Gregory M.;
O'Donnell-Luria, Anne;
Girirajan, Santhosh;
Dudley, Aimée M.;
Goriely, Anne;
Kutalik, Zoltán;
Zhu, Xiaofeng;
Sirugo, Giorgio;
Epstein, Michael P.

Publication type:

Editorial

Gut microbiota, metabolites, and cytokines in relation to the risk of prostate cancer in the Asian population.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2024.1466190

By:

Wang, Zhengshi;
Chen, Haotian;
Liu, Yongqiang;
Zou, Libin;
Zhang, Zhijin;
Yin, Zhiqiang;
Mao, Shiyu;
Guo, Changcheng;
Yang, Bin;
Wu, Pengfei;
Yao, Xudong

Publication type:

Article

Causal associations of thyroid function with inflammatory bowel disease and the mediating role of cytokines.

Published in:

Frontiers in Endocrinology, 2025, p. 1, doi. 10.3389/fendo.2024.1376139

By:

Wu, Shuyun;
Yi, Jiazhi;
Wu, Bin

Publication type:

Article

Integrated Network Toxicology and Experimental Validation Reveal the Mechanism of Bisphenol A‐Induced Kidney Injury: Targeting Macrophage Esr1 Expression and Apoptosis.

Published in:

Journal of Biochemical & Molecular Toxicology, 2025, v. 39, n. 7, p. 1, doi. 10.1002/jbt.70348

By:

Chen, Ting;
Chen, Hongtao;
Cheng, Ye;
Chen, Jiahao;
Lin, Shaoling;
Liu, Lu;
Zhan, Xiaoying;
Liu, Pei;
Xie, Guiling;
Xia, Kun;
Gao, Xianli;
Chen, Yanna;
Guo, Caiyun;
Li, Wenjun;
Ning, Wenjun;
Deng, Wenli;
Sun, Peng;
Fan, Youling;
Zhou, Jun

Publication type:

Article

Mendelian Randomization Analysis of Mitochondria‐Related Genes and Screening of Prognostic Genes in Colorectal Cancer.

Published in:

Cancer Medicine, 2025, v. 14, n. 13, p. 1, doi. 10.1002/cam4.71012

By:

Zhu, Limin;
Huang, Xiaowei;
Zhang, Fan;
Yang, Jinzu;
Xu, Zhenye

Publication type:

Article

Causal links between iron status, mitochondrial function, and laryngeal and hypopharyngeal cancers: a Mendelian study.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-03187-7

By:

Zhao, Jiandong;
Chen, Liwei;
Han, Bing;
Li, Siyang;
Zhang, Yongxia;
Gao, Ge;
Liu, Jinjing

Publication type:

Article

The diagnostic potential of unconjugated bilirubin in schizophrenia and bipolar disorder.

Published in:

BMC Psychiatry, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12888-025-07143-1

By:

Liu, Huang-Hui;
Wei, Si-Meng;
Chen, Bing-Bing;
Gao, Yao;
Xu, Yong;
Liu, Sha

Publication type:

Article

Association between Vitamin D and mortality risk in gout patients.

Published in:

Journal of Public Health, 2025, v. 47, n. 2, p. 123, doi. 10.1093/pubmed/fdaf010

By:

Fang, Xinyu;
Zhang, Jie;
Zhang, Zixing;
Ye, Dongqing

Publication type:

Article

Search for common genetic variants to allow reliable Mendelian randomization investigations into ketone metabolism.

Published in:

European Journal of Epidemiology, 2025, v. 40, n. 6, p. 649, doi. 10.1007/s10654-025-01246-5

By:

Jiesisibieke, Zhu Liduzi;
Cronjé, Héléne Toinét;
Schooling, C. Mary;
Burgess, Stephen

Publication type:

Article

Non-linear Mendelian randomization: evaluation of effect modification in the residual and doubly-ranked methods with simulated and empirical examples.

Published in:

European Journal of Epidemiology, 2025, v. 40, n. 6, p. 631, doi. 10.1007/s10654-025-01208-x

By:

Hamilton, Fergus W.;
Hughes, David A.;
Lu, Tianyuan;
Kutalik, Zoltán;
Gkatzionis, Apostolos;
Tilling, Kate;
Hartwig, Fernando P.;
Davey Smith, George

Publication type:

Article

The Negative Feedback of the Glutamine/Prostatitis Loop Identified Among 1400 Metabolites and Prostatitis via Mendelian Randomization.

Published in:

Mediators of Inflammation, 2025, v. 2025, p. 1, doi. 10.1155/mi/9648279

By:

Wang, Yi;
Ji, Hao;
Chen, Yingfei;
Zhu, Bingye;
Peng, Yongming;
Xing, Qianwei;
Mandal, Palash

Publication type:

Article

Integrating GEO Database, Mendelian Randomization, and Molecular Docking to Identify HLA‐C as a Potential Therapeutic Target for Periodontitis.

Published in:

Mediators of Inflammation, 2025, v. 2025, p. 1, doi. 10.1155/mi/9163431

By:

Shi, ChengJi;
Ou, Xinyi;
Huang, LiJuan;
Lei, XiaoXu;
Xu, ShuHao;
Ou, Menglu;
Li, Wei;
Zhao, Xi;
Giovarelli, Mirella

Publication type:

Article

Mendelian randomization analysis of gut microbiota-immune cell interactions in malignant neoplasm of nasopharynx.

Published in:

AMB Express, 2025, v. 15, n. 1, p. 1, doi. 10.1186/s13568-025-01909-2

By:

Chen, Qicong;
Wang, Gang;
Shu, Jingcheng;
Zou, Xiaosu;
Miao, Weiwei;
Nong, Wenqian;
Li, Min;
Lan, Guiping;
Huang, Wenlin;
Huang, Xueying;
Luo, Honglin;
Qu, Shenhong

Publication type:

Article

Immune and genetic landscapes of biliary atresia: a pathway to precision medicine.

Published in:

BMC Pediatrics, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12887-025-05893-1

By:

Lv, Chao;
Qi, Chengang;
Dai, Xiaoke;
Zhang, Mingman

Publication type:

Article

Unraveling the role of gut microbiota on the formation of nephrolithiasis: insights from integrated analysis of GWAS, single-cell transcriptomics, bulk RNA sequencing and network Pharmacology.

Published in:

Urolithiasis, 2025, v. 53, n. 1, p. 1, doi. 10.1007/s00240-025-01809-x

By:

Zhang, Xuhui;
Jing, Qiang;
Yao, Weitao;
Zhang, Bin;
Yuan, Xiaobin

Publication type:

Article

脂质体和循环代谢物与精神分裂症的关系: 一项两步两样本孟德尔随机化研究.

Published in:

Sichuan Mental Health, 2025, v. 38, n. 3, p. 223, doi. 10.11886/scjsws20241017001

By:

雷梦云;
杜炎宏;
高耀;
邓怀丽;
王斌红;
任智勇;
刘莎

Publication type:

Article

Causal association between modifiable risk factors and esophageal cancer: A Mendelian randomization study.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-03094-x

By:

Wang, Xiaoqing;
Zhang, Weiguang;
Lin, Tianxin;
Mao, Renyan;
Lin, Ye;
Yu, Jingchuan;
Ruan, Limin;
Lin, Jihong;
Gao, Lei;
Zhang, Peipei;
Shen, Zhimin;
Kang, Mingqiang

Publication type:

Article

Integrative genomic analysis identifies novel causal genes of Hodgkin's and non-Hodgkin's lymphoma.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-03101-1

By:

Shi, Patrick;
Baranova, Ancha;
Cao, Hongbao

Publication type:

Article

Genetic determinants of head and neck cancer: exploring causality among immune cells and plasma metabolites through two-sample Mendelian randomization and mediation analysis.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-03181-z

By:

Lu, Yuting;
Du, Xiangnan;
Liu, Hanlin;
He, Qing;
Cao, Xiaolin

Publication type:

Article

Phenotypic screening and genetic insights for predicting major vascular-related diseases using retinal imaging.

Published in:

NPJ Digital Medicine, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s41746-025-01850-5

By:

Lu, Menglin;
Mao, Yiheng;
Zhu, Hui;
Xu, Yesheng;
Yao, Yu-Feng;
Wu, Fei;
Huang, Zhengxing

Publication type:

Article

Integrative Proteomics and Genomics Identify Novel Biomarkers and Therapeutic Targets in Vitiligo via Mendelian Randomization.

Published in:

Dermatology & Therapy, 2025, v. 15, n. 8, p. 2159, doi. 10.1007/s13555-025-01448-5

By:

Yan, Chenjue;
Jiang, Ling;
Hu, Yibo;
You, Ting;
Chen, Jing;
Wu, Songjiang

Publication type:

Article

Causal relationships between inflammatory mediators, sleep traits, and cardiac magnetic resonance imaging-derived cardiac phenotypes.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-10929-8

By:

Cao, Shuhui;
Xu, Hongjie;
Tang, Yangfeng;
Xu, Zhiyun;
Yu, Shangyi

Publication type:

Article

Comprehensive analysis of Mendelian randomization and scRNA-seq identify key prognostic genes and relevant functional roles in colorectal cancer.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-10354-x

By:

Hu, Meng;
Dong, Haotian;
Chen, Chujia;
Ye, Chengyuan;
Yan, Jianing;
Yu, Xuan;
Ye, Guoliang;
Shao, Yongfu

Publication type:

Article

Identification of potential drug targets for achalasia from genetic insights: a Mendelian randomization study.

Published in:

Journal of Cardiothoracic Surgery, 2025, v. 20, n. 1, p. 1, doi. 10.1186/s13019-025-03538-z

By:

Xiong, Kai;
Fang, Hao;
Song, Caihong;
Tuerxun, Dilihumaer;
Zhang, Peng

Publication type:

Article

3-Hydroxybutyrate, a metabolite in sustaining neuronal cell vitality: a mendelian randomization and in vitro experimentation.

Published in:

Nutrition & Metabolism, 2025, v. 22, n. 1, p. 1, doi. 10.1186/s12986-025-00960-x

By:

Hu, Xiaoling;
Lin, Yu;
Huang, Kaiwen;
Xu, HuiLin;
Fu, Changmei Huang;
Ou, Jiayin;
Fan, Xiude;
Li, Zhe;
Fang, Jiansong;
Fang, Shuhuan

Publication type:

Article

Smoking promotes the progression of bladder cancer through FOXM1/CKAP2L axis.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06835-2

By:

Wu, Feixiang;
Wu, Shasha;
Huang, Yu;
Xiao, Xiao;
Yu, Haitao;
Bai, Xuesong;
Zhang, Chunlin;
Feng, Zhenwei;
Li, Li;
Mei, Yuhua;
Li, Xinyuan;
Gou, Xin

Publication type:

Article

Derivatives of the triglyceride–glucose index and their association with incident hypertension in prehypertensive individuals: a 4-year cohort study augmented by mendelian randomization.

Published in:

Cardiovascular Diabetology, 2025, v. 24, n. 1, p. 1, doi. 10.1186/s12933-025-02813-6

By:

Wang, Mengmeng;
Teng, Tianqi;
Zhang, Nan;
Xu, Jiachao;
Dong, Zihan;
Jiao, Qingying;
Zhang, Ning;
Yu, Haichu

Publication type:

Article

Dietary intake and five types of mental disorders: a bidirectional Mendelian randomization study.

Published in:

BMC Psychiatry, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12888-025-07100-y

By:

Zhang, Yichun;
Zhang, Mingzhu;
Guan, Qihua;
Liu, Pengcheng;
Zhang, Wangxin;
Yang, Song;
Dong, Hualei;
Hou, Haifeng

Publication type:

Article

A multivariable cis-Mendelian randomization method robust to weak instrument bias and horizontal pleiotropy bias Open Access.

Published in:

Briefings in Bioinformatics, 2025, v. 26, n. 3, p. 1, doi. 10.1093/bib/bbaf250

By:

Yang, Yihe;
Lorincz-Comi, Noah;
Li, Mengxuan;
Zhu, Xiaofeng

Publication type:

Article

Accounting for the impact of rare variants on causal inference with RARE: a novel multivariable Mendelian randomization method Open Access.

Published in:

Briefings in Bioinformatics, 2025, v. 26, n. 3, p. 1, doi. 10.1093/bib/bbaf214

By:

Cheng, Yu;
Ruan, Xinjia;
Lu, Xiaofan;
Yang, Yuqing;
Wang, Yuhang;
Yan, Shangjin;
Sun, Yuzhe;
Yan, Fangrong;
Jiang, Liyun;
Liu, Tiantian

Publication type:

Article

The Causal Correlation Between Gastroesophageal Reflux Disease and Chronic Widespread Pain: A Bidirectional Mendelian Randomization Study.

Published in:

Journal of Pain Research, 2025, v. 18, p. 3107, doi. 10.2147/JPR.S494166

By:

Chen, Menglin;
Tu, Houshu;
Zhou, Jiaoli;
Zhang, Yi;
Wen, Shuting;
Xiao, Yao;
He, Ling

Publication type:

Article

Assessing the Causal Effect of Pulse Pressure on Migraine Risk: A Mendelian Randomization Study.

Published in:

Journal of Pain Research, 2025, v. 18, p. 3159, doi. 10.2147/JPR.S512795

By:

Xu, Hongli;
Qin, Xiaoyan;
Feng, Zeguo;
You, Shaohua

Publication type:

Article

Mapping the Brain's Role in Osteoarthritis: New Evidence for Prevention.

Published in:

Journal of Multidisciplinary Healthcare, 2025, v. 18, p. 3605, doi. 10.2147/JMDH.S522952

By:

Di, Jingkai;
Xi, Yujia;
Liu, Yaru;
Qi, Likun;
Chen, Shuai;
Qin, Yingda;
Xiang, Chuan

Publication type:

Article

Chronic Lung Diseases and Depressive Symptoms in Older Adults: Insights from Observational Studies and Mendelian Randomization.

Published in:

Journal of Multidisciplinary Healthcare, 2025, v. 18, p. 3465, doi. 10.2147/JMDH.S515745

By:

Liu, Huifang;
Yao, Yisong;
Yang, Yujuan;
Wang, Jianwei;
Yu, Jingyi;
Xu, Xinjun;
Luo, Xianghuang;
Zhang, Yu;
Song, Xicheng

Publication type:

Article

Causal Effects of Immune Cells on Reproductive Ill-Health, Including Abnormal Spermatozoa, Polycystic Ovary Syndrome and Spontaneous Abortion: Mendelian Randomization Analyses.

Published in:

Journal of Multidisciplinary Healthcare, 2025, v. 18, p. 3219, doi. 10.2147/JMDH.S524949

By:

Chen, Shuang;
Sun, Shihao;
Zhou, Zihan;
Zhou, Zhaokai;
Zhang, Ran;
Song, Wenyan;
Xin, Hang;
Yang, Qingling;
Dai, Shanjun;
Huang, Kai;
Niu, Wenbin;
Shi, Hao;
Guo, Yihong

Publication type:

Article