Works about MELANOCORTIN receptors

Results: 742

Effects of pine needle essential oil on melanin synthesis in B16F10 cells and its mechanism.

Published in:

Biomedical Reports, 2025, v. 23, n. 2, p. N.PAG, doi. 10.3892/br.2025.2011

By:

Lü, Suyuan;
Shang, Bingqing;
Liu, Guolong;
Sun, Luyan;
Wu, Qiu;
Geng, Yue

Publication type:

Article

Improving the diagnosis of hyperphagia in melanocortin‐4 receptor pathway diseases.

Published in:

Obesity (19307381), 2025, v. 33, n. 7, p. 1217, doi. 10.1002/oby.24287

By:

Abuzzahab, M. Jennifer;
Dubern, Beatrice;
Goldstone, Anthony P.;
Haqq, Andrea M.;
Heymsfield, Steven B.;
Miller, Jennifer L.;
Richards, Jesse;
Wabitsch, Martin;
Yanovski, Jack A.

Publication type:

Article

The role of polygenic susceptibility to obesity among carriers of pathogenic mutations in MC4R in the UK Biobank population.

Published in:

2020

By:

Chami, Nathalie;
Preuss, Michael;
Walker, Ryan W.;
Moscati, Arden;
Loos, Ruth J. F.

Publication type:

journal article

Effects of Hypothalamic Neurodegeneration on Energy Balance.

Published in:

PLoS Biology, 2005, v. 3, n. 11, p. 1, doi. 10.1371/journal.pbio.0030415

By:

Xu, Allison Wanting;
Kaelin, Christopher B;
Morton, Gregory J;
Ogimoto, Kayoko;
Stanhope, Kimber;
Graham, James;
Baskin, Denis G;
Havel, Peter;
Schwartz, Michael W;
Barsh, Gregory S

Publication type:

Article

The MC4R SNPs, their haplotypes and gene-environment interactions on the risk of obesity.

Published in:

Molecular Medicine, 2020, v. 26, n. 1, p. 1, doi. 10.1186/s10020-020-00202-1

By:

Wei, Bi-Liu;
Yin, Rui-Xing;
Liu, Chun-Xiao;
Deng, Guo-Xiong;
Guan, Yao-Zong;
Zheng, Peng-Fei

Publication type:

Article

Effects of melanocortin-4 receptor agonists and antagonists on expression of genes related to reproduction in spotted scat, Scatophagus argus.

Published in:

Journal of Comparative Physiology B: Biochemical, Systemic & Environmental Physiology, 2017, v. 187, n. 4, p. 603, doi. 10.1007/s00360-017-1062-0

By:

Jiang, Dong-Neng;
Li, Jian-Tao;
Tao, Ya-Xiong;
Chen, Hua-Pu;
Deng, Si-Ping;
Zhu, Chun-Hua;
Li, Guang-Li

Publication type:

Article

Analysis of the genetic variation in mitochondrial DNA, Y-chromosome sequences, and MC1R sheds light on the ancestry of Nigerian indigenous pigs.

Published in:

Genetics Selection Evolution, 2017, v. 49, p. 1, doi. 10.1186/s12711-017-0326-1

By:

Adeola, Adeniyi C.;
Oluwole, Olufunke O.;
Oladele, Bukola M.;
Olorungbounmi, Temilola O.;
Boladuro, Bamidele;
Olaogun, Sunday C.;
Nneji, Lotanna M.;
Sanke, Oscar J.;
Dawuda, Philip M.;
Omitogun, Ofelia G.;
Frantz, Laurent;
Murphy, Robert W.;
Hai-Bing Xie;
Min-Sheng Peng;
Ya-Ping Zhang

Publication type:

Article

A Novel Maternally Inherited GNAS Variant in a Family With Hyperphagia and Obesity: 3 Cases.

Published in:

JCEM Case Reports, 2024, v. 2, n. 8, p. 1, doi. 10.1210/jcemcr/luae125

By:

Ramakrishnan, Anand;
Popat, Dillon;
Purushothaman, Preetha;
Chan, Li F.;
Gevers, Evelien F.

Publication type:

Article

Screening of MC4R, LEP, LEPR, POMC, SH2B1, and SIM1 genes in Turkish children with severe early-onset obesity.

Published in:

Medicine Science, 2021, v. 10, n. 2, p. 328, doi. 10.5455/medscience.2020.10.211

By:

Turkyilmaz, Ayberk;
Yarali, Oguzhan;
Kurnaz, Erdal;
Cayir, Atilla

Publication type:

Article

Polymorphism of Melanocortin-4 Receptor Gene and Its Association with Growth Traits in Bali Cattle.

Published in:

Indonesian Journal of Animal & Veterinary Sciences / Jurnal Ilmu Ternak dan Veteriner, 2023, v. 28, n. 3, p. 177, doi. 10.14334/jitv.v28i3.3163

By:

R. Y., Kusminanto;
F. A., Hazimi;
V. P. A., Ceri;
Panjono;
T., Hartatik

Publication type:

Article

Common Genetic Variation in MC4R Does Not Affect Atherosclerotic Plaque Phenotypes and Cardiovascular Disease Outcomes.

Published in:

Journal of Clinical Medicine, 2021, v. 10, n. 5, p. 932, doi. 10.3390/jcm10050932

By:

Blauw, Lisanne L.;
Noordam, Raymond;
van der Laan, Sander W.;
Trompet, Stella;
Kooijman, Sander;
van Heemst, Diana;
Jukema, Johan Wouter;
van Setten, Jessica;
de Borst, Gert J.;
Tybjærg-Hansen, Anne;
Pasterkamp, Gerard;
Berbée, Jimmy F. P.;
Rensen, Patrick C. N.;
Gresele, Paolo

Publication type:

Article

Melanocortin 3 Receptor in Neural Circuits Linking Metabolic State with Reproduction and Growth.

Published in:

Journal of Animal Science, 2023, v. 101, p. 231, doi. 10.1093/jas/skad281.280

By:

Bedenbaugh, Michelle N.;
Sweet, Serena;
Mendoza-Romero, Haley;
Brener, Samantha;
Hawkins, Sydney;
Gina Yu;
Zimmermann, Jessie;
Sweeney, Patrick;
Cone, Roger;
Simerly, Richard

Publication type:

Article

Synergy between MC1R and ASIP for coat color in horses (Equus caballus).

Published in:

Journal of Animal Science, 2019, v. 97, n. 4, p. 1578, doi. 10.1093/jas/skz071

By:

Shang, Songyang;
Yu, Yan;
Zhao, Yuxin;
Dang, Wanyi;
Zhang, Junpeng;
Qin, Xia;
Irwin, David M;
Wang, Qin;
Liu, Fei;
Wang, Zhenshan;
Zhang, Shuyi;
Wang, Zhe

Publication type:

Article

An intervention study demonstrates effects of MC4R genotype on boar taint and performances of growing-finishing pigs.

Published in:

Journal of Animal Science, 2015, v. 93, n. 3, p. 934, doi. 10.2527/jas.2014-8184

By:

Van den Broeke, A.;
Aluwé, M.;
Tuyttens, F. A. M.;
Ampe, B.;
Vanhaecke, L.;
Wauters, J.;
Janssens, S.;
Coussé, A.;
Buys, N.;
Millet, S.

Publication type:

Article

Dimethyl Itaconate Inhibits Melanogenesis in B16F10 Cells.

Published in:

Antioxidants, 2023, v. 12, n. 3, p. 692, doi. 10.3390/antiox12030692

By:

Yu, Bo-Yeong;
Ngo, Hoang Hai;
Choi, Won Jun;
Keum, Young-Sam

Publication type:

Article

Glucagon-like peptide-1 receptor activation stimulates PKA-mediated phosphorylation of Raptor and this contributes to the weight loss effect of liraglutide.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.80944

By:

Le, Thao D. V.;
Liu, Dianxin;
Besing, Gai-Linn K.;
Raghavan, Ritika;
Ellis, Blair J.;
Ceddia, Ryan P.;
Collins, Sheila;
Ayala, Julio E.

Publication type:

Article

Melanocortin 1 receptor regulates cholesterol and bile acid metabolism in the liver.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.84782

By:

Thapa, Keshav;
Kadiri, James J.;
Saukkonen, Karla;
Pennanen, Iida;
Ghimire, Bishwa;
Minying Cai;
Savontaus, Eriika;
Rinne, Petteri

Publication type:

Article

Born blonde: a recessive loss-of-function mutation in the melanocortin 1 receptor is associated with cream coat coloration in Antarctic fur seals.

Published in:

Ecology & Evolution (20457758), 2016, v. 6, n. 16, p. 5705, doi. 10.1002/ece3.2290

By:

Peters, Lucy;
Humble, Emily;
Kröcker, Nicole;
Fuchs, Birgit;
Forcada, Jaume;
Hoffman, Joseph I.

Publication type:

Article

MC4-R variant confirms its association with obesity during progression from childhood to adolescence.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-96408-6

By:

Mohn, Angelika;
Di Ludovico, Armando;
Polidori, Nella;
Giannini, Cosimo;
Di Pietro, Giada;
Lauriola, Federico;
Chiarelli, Francesco

Publication type:

Article

Effect of Hepatic and Renal Impairment on the Pharmacokinetics of Dersimelagon (MT‐7117), an Oral Melanocortin‐1 Receptor Agonist.

Published in:

Clinical Pharmacology in Drug Development, 2024, v. 13, n. 7, p. 729, doi. 10.1002/cpdd.1413

By:

Ogasawara, Akihito;
Ide, Ryosuke;
Inoue, Shinsuke;
Teng, Renli;
Kawaguchi, Atsuhiro

Publication type:

Article

The Oral Bioavailability and Effect of Various Gastric Conditions on the Pharmacokinetics of Dersimelagon in Healthy Adult Volunteers.

Published in:

Clinical Pharmacology in Drug Development, 2023, v. 12, n. 5, p. 493, doi. 10.1002/cpdd.1235

By:

Ogawa, Kei;
Ide, Ryosuke;
Belongie, Kirstine;
Tsuda, Minoru;
Kawanishi, Hiroki;
Teng, Renli;
Ogasawara, Akihito

Publication type:

Article

Canine coat color E locus updates: Identification of a new MC1R variant causing 'sable' coat color in English Cocker Spaniels and a proposed update to the E locus dominance hierarchy.

Published in:

Animal Genetics, 2024, v. 55, n. 2, p. 291, doi. 10.1111/age.13398

By:

Honkanen, Leena;
Loechel, Robert;
Davison, Stephen;
Donner, Jonas;
Anderson, Heidi

Publication type:

Article

Genome‐wide analyses based on a novel donkey 40K liquid chip reveal the gene responsible for coat color diversity in Chinese Dezhou donkey.

Published in:

Animal Genetics, 2024, v. 55, n. 1, p. 140, doi. 10.1111/age.13379

By:

Liu, Shuqin;
Su, Jiangtian;
Yang, Qiwen;
Sun, Minhao;
Wang, Zhaofei;
Yu, Jie;
Jafari, Halima;
Lei, Chuzhao;
Sun, Yujiang;
Dang, Ruihua

Publication type:

Article

Melanocortin‐4 receptor and proopiomelanocortin: Candidate genes for obesity in domestic shorthair cats.

Published in:

Animal Genetics, 2023, v. 54, n. 5, p. 637, doi. 10.1111/age.13335

By:

Jerjen, C. P.;
Kumaran, S. J.;
Liesegang, A.;
Hall, E.;
Wichert, B.;
Haase, B.

Publication type:

Article

Functional characterization of cAMP signaling of variant porcine MC1R alleles in PK15 cells.

Published in:

Animal Genetics, 2022, v. 53, n. 3, p. 317, doi. 10.1111/age.13189

By:

Lan, Jin;
Wang, Min;
Qin, Ke;
Liu, Xiaofeng;
Shi, Xuan;
Sun, Guanjie;
Liu, Xiaohong;
Chen, Yaosheng;
He, Zuyong

Publication type:

Article

The Asp298Asn polymorphism of melanocortin‐4 receptor (MC4R) in pigs: evidence for its potential effects on MC4R constitutive activity and cell surface expression.

Published in:

Animal Genetics, 2020, v. 51, n. 5, p. 694, doi. 10.1111/age.12986

By:

Zhang, J.;
Li, J.;
Wu, C.;
Hu, Z.;
An, L.;
Wan, Y.;
Fang, C.;
Zhang, X.;
Wang, Y.

Publication type:

Article

Haplotypes of three missense mutations in Melanocortin 1 receptor serve as genetic markers for black plumage in Chinese chicken.

Published in:

Animal Genetics, 2020, v. 51, n. 5, p. 842, doi. 10.1111/age.12975

By:

Deng, Yonglin;
Li, Baisen;
Chen, Huiyou;
Zhang, Jianmin;
Yan, Yi;
Xiang, Jialin;
Liu, Anfang;
Zhang, Gong‐Wei

Publication type:

Article

Association of a novel SNP in the ASIP gene with skin color in black‐bone chicken.

Published in:

Animal Genetics, 2019, v. 50, n. 3, p. 283, doi. 10.1111/age.12768

By:

Yu, S.;
Wang, G.;
Liao, J.

Publication type:

Article

Signatures of de‐domestication in autochthonous pig breeds and of domestication in wild boar populations from MC1R and NR6A1 allele distribution.

Published in:

Animal Genetics, 2019, v. 50, n. 2, p. 166, doi. 10.1111/age.12771

By:

Ribani, A.;
Utzeri, V. J.;
Geraci, C.;
Tinarelli, S.;
Djan, M.;
Veličković, N.;
Doneva, R.;
Dall'Olio, S.;
Nanni Costa, L.;
Schiavo, G.;
Bovo, S.;
Usai, G.;
Gallo, M.;
Radović, Č.;
Savić, R.;
Karolyi, D.;
Salajpal, K.;
Gvozdanović, K.;
Djurkin‐Kušec, I.;
Škrlep, M.

Publication type:

Article

A new dominant haplotype of MC1R gene in Chinese black plumage chicken.

Published in:

Animal Genetics, 2017, v. 48, n. 5, p. 624, doi. 10.1111/age.12576

By:

Zhang, Gong‐Wei;
Liao, Yonglan;
Zhang, Wen‐Xiu;
Wu, Yuhui;
Liu, Anfang

Publication type:

Article

Sri Lankan pig ancestry revealed by mitochondrial DNA, Y-chromosome, and MC1R.

Published in:

Animal Genetics, 2017, v. 48, n. 5, p. 622, doi. 10.1111/age.12577

By:

Hirimuthugoda, Nalini Yasoda;
Adeola, Adeniyi C.;
Anthony Perera, Patthamesthrige Wimal;
Chen, Xing;
Dewar Asoka Gunawardena, Weligalle Wedarallage;
Thilini Nisanka Gunawardana, Humpita Gamaralalage;
Yin, Ting‐Ting;
Wang, Ming‐Shan;
Li, Gui‐Mei;
Ding, Zhao‐Li;
Wang, Wen‐Zhi;
Xie, Hai‐Bing;
Peng, Min‐Sheng;
Zhang, Ya‐Ping

Publication type:

Article

A novel mutation in the TYRP1 gene associated with brown coat colour in the Australian Shepherd Dog Breed.

Published in:

Animal Genetics, 2017, v. 48, n. 5, p. 626, doi. 10.1111/age.12563

By:

Hrckova Turnova, Evelina;
Majchrakova, Zuzana;
Bielikova, Marcela;
Soltys, Katarina;
Turna, Jan;
Dudas, Andrej

Publication type:

Article

Not another type of potato: MC1R and the russet coloration of Burmese cats.

Published in:

Animal Genetics, 2017, v. 48, n. 1, p. 116, doi. 10.1111/age.12505

By:

Gustafson, N. A.;
Gandolfi, B.;
Lyons, L. A.

Publication type:

Article

Association analysis between feed efficiency studies and expression of hypothalamic neuropeptide genes in laying ducks.

Published in:

Animal Genetics, 2016, v. 47, n. 5, p. 606, doi. 10.1111/age.12457

By:

Zeng, T.;
Chen, L.;
Du, X.;
Lai, S. J.;
Huang, S. P.;
Liu, Y. L.;
Lu, L. Z.

Publication type:

Article

Effect of melanocortin 1 receptor ( MC1R) polymorphism on coat colour variation in nutrias ( Myocastor coypus Mol.).

Published in:

Animal Genetics, 2014, v. 45, n. 6, p. 909, doi. 10.1111/age.12231

By:

Migdał, Ł.;
Ząbek, T.;
Migdał, A.;
Łapiński, S.;
Maj, D.;
Bieniek, J.;
Fornal, A.;
Bugno‐Poniewierska, M.

Publication type:

Article

Two missense mutations in melanocortin 1 receptor ( MC1R) are strongly associated with dark ventral coat color in reindeer ( Rangifer tarandus).

Published in:

Animal Genetics, 2014, v. 45, n. 5, p. 750, doi. 10.1111/age.12187

By:

Våge, D. I.;
Nieminen, M.;
Anderson, D. G.;
Røed, K. H.

Publication type:

Article

Variability in the melanocortin 1 receptor ( MC1R) gene in wild boars and local pig breeds in Poland.

Published in:

Animal Genetics, 2013, v. 44, n. 3, p. 357, doi. 10.1111/age.12023

By:

Babicz, Marek;
Pastwa, Marcin;
Skrzypczak, Ewa;
Buczyński, Janusz T.

Publication type:

Article

Interaction of MC1R and PMEL alleles on solid coat colors in Highland cattle.

Published in:

Animal Genetics, 2013, v. 44, n. 1, p. 9, doi. 10.1111/j.1365-2052.2012.02361.x

By:

Schmutz, Sheila M.;
Dreger, Dayna L.

Publication type:

Article

Editorial: Melanocortins and melanocortin receptors in the regulation of inflammation: mechanisms and novel therapeutic strategies.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1226886

By:

Rinne, Petteri;
Taylor, Andrew W.;
Montero-Melendez, Trinidad

Publication type:

Article

Identification of a Rare and Potential Pathogenic MC4R Variant in a Brazilian Patient With Adulthood-Onset Severe Obesity.

Published in:

Frontiers in Genetics, 2020, v. 11, p. N.PAG, doi. 10.3389/fgene.2020.608840

By:

Salum, Kaio Cezar Rodrigues;
de Souza, Guilherme Orofino;
Abreu, Gabriella de Medeiros;
Campos Junior, Mário;
Kohlrausch, Fabiana Barzotto;
Carneiro, João Regis Ivar;
Nogueira Neto, José Firmino;
Magno, Fernanda Cristina C. Mattos;
Rosado, Eliane Lopes;
Palhinha, Lohanna;
Maya-Monteiro, Clarissa Menezes;
Cabello, Giselda Maria Kalil de;
Cabello, Pedro Hernán;
Bozza, Patrícia Torres;
Zembrzuski, Verônica Marques;
da Fonseca, Ana Carolina Proença

Publication type:

Article

MicroRNA-206 Regulation of Skin Pigmentation in Koi Carp (Cyprinus carpio L.).

Published in:

Frontiers in Genetics, 2020, p. 1, doi. 10.3389/fgene.2020.00047

By:

Dong, Zaijie;
Luo, Mingkun;
Wang, Lanmei;
Yin, Haoran;
Zhu, Wenbin;
Fu, Jianjun

Publication type:

Article

Genetic variants in the MC4R gene and risk of obesity/overweight: A systematic review and meta‐analysis.

Published in:

Diabetes, Obesity & Metabolism, 2025, v. 27, n. 7, p. 3901, doi. 10.1111/dom.16425

By:

Cheraghi, Sara;
Mobaderi, Tofigh;
Mottaghi, Azadeh;
Movahedi Motlagh, Fatemeh;
Taghizadeh, Sara;
Eghbali, Maryam

Publication type:

Article

The melanocortin‐4 receptor pathway and the emergence of precision medicine in obesity management.

Published in:

Diabetes, Obesity & Metabolism, 2024, v. 26, p. 46, doi. 10.1111/dom.15555

By:

Fansa, Sima;
Acosta, Andres

Publication type:

Article

Effect of bremelanotide on body weight of obese women: Data from two phase 1 randomized controlled trials.

Published in:

Diabetes, Obesity & Metabolism, 2022, v. 24, n. 6, p. 1084, doi. 10.1111/dom.14672

By:

Spana, Carl;
Jordan, Robert;
Fischkoff, Steven

Publication type:

Article

Interactions of amylinergic and melanocortinergic systems in the control of food intake and body weight in rodents.

Published in:

Diabetes, Obesity & Metabolism, 2012, v. 14, n. 7, p. 608, doi. 10.1111/j.1463-1326.2012.01570.x

By:

Roth, J. D.;
D'Souza, L.;
Griffin, P. S.;
Athanacio, J.;
Trevaskis, J. L.;
Nazarbaghi, R.;
Jodka, C.;
Hoyt, J.;
Forood, B.;
Parkes, D. G.

Publication type:

Article

The Role of Alpha-MSH as a Modulator of Ocular Immunobiology Exemplifies Mechanistic Differences between Melanocortins and Steroids.

Published in:

2017

By:

Clemson, Christine M.;
Yost, John;
Taylor, Andrew W.

Publication type:

journal article

Association Analysis of Melanocortin 3 Receptor Polymorphisms with the Risk of Pulmonary Tuberculosis.

Published in:

2014

By:

Park, Byung;
Kim, Lyoung;
Namgoong, Suhg;
Kim, Ji;
Kim, Jason;
Chang, Hun;
Park, Jong;
Jang, An;
Park, Sung;
Kim, Do;
Kim, Ki;
Kim, Yang;
Uh, Soo-Taek;
Seo, Ki;
Kim, Young;
Park, Choon;
Shin, Hyoung

Publication type:

Report

Efficacy of the melanocortin analogue Nle4-D-Phe7-α-melanocyte-stimulating hormone in the treatment of patients with Hailey-Hailey disease.

Published in:

Clinical & Experimental Dermatology, 2014, v. 39, n. 2, p. 168, doi. 10.1111/ced.12203

By:

Biolcati, G.;
Aurizi, C.;
Barbieri, L.;
Cialfi, S.;
Screpanti, I.;
Talora, C.

Publication type:

Article

Effects of chronic nicotine treatment on MC3R and MC4R mRNA expression in the rat brain.

Published in:

Anatomy: International Journal of Experimental & Clinical Anatomy, 2019, v. 13, n. S1, p. S67

By:

Tapınç, Damla Ece;
Kaya, Egemen;
Gözen, Oğuz;
Koylu, Ersin Oğuz;
Kanıt, Lütfiye;
Keser, Ayşegül;
Balkan, Burcu

Publication type:

Article

Haplotype diversity in <italic>MC1R</italic> locus between the Min and white-haired pig breeds.

Published in:

Acta Agriculturae Scandinavica: Section A, Animal Science, 2017, v. 67, n. 1/2, p. 28, doi. 10.1080/09064702.2017.1337215

By:

Lu, C.;
Yu, H.;
Xing, Y.;
Cheng, Y.-Y.;
Wu, Q.-Y.;
Li, S.-M.;
Fu, H.-Y.;
Zhang, X.;
Hao, L.-L.;
Liu, D.

Publication type:

Article