Works matching DE "MEGALIN"

Results: 42

Vitamin D receptor and megalin gene polymorphisms are associated with central adiposity status and changes among US adults.

Published in:

Journal of Nutritional Science, 2013, v. 2, p. 1, doi. 10.1017/jns.2013.19

By:

Beydoun, May A.;
Toshiko Tanaka;
Beydoun, Hind A.;
Ding, Eric L.;
Ferrucci, Luigi;
Zonderman, Alan B.

Publication type:

Article

The role of the Lowe syndrome protein OCRL in the endocytic pathway.

Published in:

Biological Chemistry, 2015, v. 396, n. 12, p. 1293, doi. 10.1515/hsz-2015-0180

By:

Sharma, Shruti;
Skowronek, Agnieszka;
Erdmann, Kai Sven

Publication type:

Article

Renal phenotypic investigations of megalin-deficient patients: novel insights into tubular proteinuria and albumin filtration*.

Published in:

Nephrology Dialysis Transplantation, 2013, v. 28, n. 3, p. 585, doi. 10.1093/ndt/gfs462

By:

Storm, Tina;
Tranebjærg, Lisbeth;
Frykholm, Carina;
Birn, Henrik;
Verroust, Pierre J.;
Nevéus, Tryggve;
Sundelin, Birgitta;
Hertz, Jens Michael;
Holmström, Gerd;
Ericson, Katharina;
Christensen, Erik I.;
Nielsen, Rikke

Publication type:

Article

Cubilin is expressed in rat and human glomerular podocytes.

Published in:

Nephrology Dialysis Transplantation, 2012, v. 27, n. 8, p. 3156, doi. 10.1093/ndt/gfr794

By:

Prabakaran, Thaneas;
Christensen, Erik Ilsø;
Nielsen, Rikke;
Verroust, Pierre J.

Publication type:

Article

Combination therapy of cisplatin with cilastatin enables an increased dose of cisplatin, enhancing its antitumor effect by suppression of nephrotoxicity.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-020-80853-6

By:

Arita, Masashi;
Watanabe, Satoshi;
Aoki, Nobumasa;
Kuwahara, Shoji;
Suzuki, Ryo;
Goto, Sawako;
Abe, Yuko;
Takahashi, Miho;
Sato, Miyuki;
Hokari, Satoshi;
Ohtsubo, Aya;
Shoji, Satoshi;
Nozaki, Koichiro;
Ichikawa, Kosuke;
Kondo, Rie;
Hayashi, Masachika;
Ohshima, Yasuyoshi;
Kabasawa, Hideyuki;
Hosojima, Michihiro;
Koya, Toshiyuki

Publication type:

Article

Physiopathologie des glomérulopathies extramembraneuses Cinquante ans de progrès, du laboratoire au patient.

Published in:

Biologie Aujourd'hui, 2013, v. 207, n. 4, p. 249, doi. 10.1051/jbio/2013025

By:

Ronco, Pierre;
Debiec, Hanna

Publication type:

Article

Reduced tubular proteinuria in hypertensive rats treated with losartan is associated with higher renal cortical megalin expression.

Published in:

Hormone Molecular Biology & Clinical Investigation, 2014, v. 18, n. 2, p. 105, doi. 10.1515/hmbci-2013-0061

By:

Arruda-Junior, Daniel F.;
Virgulino, Stephannie G.;
Girardi, Adriana C.C.

Publication type:

Article

Chaperone-Mediated Autophagy Upregulation Rescues Megalin Expression and Localization in Cystinotic Proximal Tubule Cells.

Published in:

Frontiers in Endocrinology, 2019, p. N.PAG, doi. 10.3389/fendo.2019.00021

By:

Zhang, Jinzhong;
He, Jing;
Johnson, Jennifer L.;
Rahman, Farhana;
Gavathiotis, Evripidis;
Cuervo, Ana Maria;
Catz, Sergio D.

Publication type:

Article

Increasing l-isoleucine production in Corynebacterium glutamicum by overexpressing global regulator Lrp and two-component export system Brn FE.

Published in:

Journal of Applied Microbiology, 2013, v. 114, n. 5, p. 1369, doi. 10.1111/jam.12141

By:

Yin, L.;
Shi, F.;
Hu, X.;
Chen, C.;
Wang, X.

Publication type:

Article

Dysregulation of the Intrarenal Vitamin D Endocytic Pathway in a Nephropathy-Prone Mouse Model of Type 1 Diabetes.

Published in:

Experimental Diabetes Research, 2011, p. 1, doi. 10.1155/2011/269378

By:

Fowlkes, John L.;
Bunn, R. Clay;
Cockrell, Gael E.;
Clark, Lindsey M.;
Wahl, Elizabeth C.;
Lumpkin, Charles K.;
Thrailkill, Kathryn M.

Publication type:

Article

Significance of Urinary Full-Length and Ectodomain Forms of Megalin in Patients With Type 2 Diabetes.

Published in:

Diabetes Care, 2012, v. 35, n. 5, p. 1112, doi. 10.2337/dc11-1684

By:

Ogasawara, Shinya;
Hosojima, Michihiro;
Kaseda, Ryohei;
Kabasawa, Hideyuki;
Yamamoto-Kabasawa, Keiko;
Kurosawa, Hiroyuki;
Sato, Hiroyoshi;
Iino, Noriaki;
Takeda, Tetsuro;
Suzuki, Yoshiki;
Narita, Ichiei;
Yamagata, Kunihiro;
Tomino, Yasuhiko;
Gejyo, Fumitake;
Hirayama, Yoshiaki;
Sekine, Sakari;
Saito, Akihiko

Publication type:

Article

Bone marrow cells contribute to tubular epithelium regeneration following acute kidney injury induced by mercuric chloride.

Published in:

Indian Journal of Medical Research, 2012, v. 136, n. 2, p. 211

By:

Yadav, Neelam;
Rao, Someshwara;
Bhowmik, Dipankar M.;
Mukhopadhyay, Asok

Publication type:

Article

Lack of megalin expression in adult human terminal ileum suggests megalin-independent cubilin/amnionless activity during vitamin B<sub>12</sub> absorption.

Published in:

Physiological Reports, 2014, v. 2, n. 7, p. n/a, doi. 10.14814/phy2.12086

By:

Jensen, Louise L.;
Andersen, Rikke K.;
Hager, Henrik;
Madsen, Mette

Publication type:

Article

Melanoma tumors frequently acquire LRP2/megalin expression, which modulates melanoma cell proliferation and survival rates.

Published in:

Pigment Cell & Melanoma Research, 2015, v. 28, n. 3, p. 267, doi. 10.1111/pcmr.12352

By:

Andersen, Rikke K.;
Hammer, Katrine;
Hager, Henrik;
Christensen, Julie N.;
Ludvigsen, Maja;
Honoré, Bent;
Thomsen, Mai ‐ Britt H.;
Madsen, Mette

Publication type:

Article

Exocytosis-Mediated Urinary Full-Length Megalin Excretion Is Linked With the Pathogenesis of Diabetic Nephropathy.

Published in:

2017

By:

De, Shankhajit;
Shoji Kuwahara;
Michihiro Hosojima;
Tomomi Ishikawa;
Ryohei Kaseda;
Piyali Sarkar;
Yusuke Yoshioka;
Hideyuki Kabasawa;
Tomomichi Iida;
Sawako Goto;
Koji Toba;
Yuki Higuchi;
Yoshiki Suzuki;
Masanori Hara;
Hiroyuki Kurosawa;
Ichiei Narita;
Yoshiaki Hirayama;
Takahiro Ochiya;
Akihiko Saito;
Kuwahara, Shoji

Publication type:

journal article

Endocytic receptor LRP2/megalin-of holoprosencephaly and renal Fanconi syndrome.

Published in:

Pflügers Archiv: European Journal of Physiology, 2017, v. 469, n. 7/8, p. 907, doi. 10.1007/s00424-017-1992-0

By:

Willnow, Thomas;
Christ, Annabel

Publication type:

Article

Patients with primary membranous nephropathy lack auto-antibodies against LDL receptor, the homologue of megalin in human glomeruli.

Published in:

Clinical Kidney Journal, 2012, v. 5, n. 2, p. 178, doi. 10.1093/ndtplus/sfp002

By:

Bruschi, Maurizio;
Candiano, Giovanni;
Murtas, Corrado;
Prunotto, Marco;
Santucci, Laura;
Carnevali, Maria Luisa;
Scolari, Francesco;
Allegri, Landino;
Ghiggeri, Gian Marco

Publication type:

Article

Megalin dependent urinary cystatin C excretion in ischemic kidney injury in rats.

Published in:

PLoS ONE, 2017, v. 12, n. 6, p. 1, doi. 10.1371/journal.pone.0178796

By:

Jensen, Danny;
Kierulf-Lassen, Casper;
Kristensen, Marie Louise Vindvad;
Nørregaard, Rikke;
Weyer, Kathrin;
Nielsen, Rikke;
Christensen, Erik Ilsø;
Birn, Henrik

Publication type:

Article

Urinary megalin in association with progression factors of diabetic nephropathy.

Published in:

Bratislava Medical Journal / Bratislavské Lekárske Listy, 2019, v. 120, n. 7, p. 532, doi. 10.4149/BLL_2019_086

By:

Akour, A.;
Kasabri, V.;
Bulatova, N.;
Al-Motassem, Y.;
Fahmawi, H.;
Momani, M.;
Zayed, A.;
Alquoqa, R.;
AlHawari, H.

Publication type:

Article

Megalin mediates plasma membrane to mitochondria cross-talk and regulates mitochondrial metabolism.

Published in:

Cellular & Molecular Life Sciences, 2018, v. 75, n. 21, p. 4021, doi. 10.1007/s00018-018-2847-3

By:

Li, Qingtian;
Lei, Fan;
Tang, Yi;
Pan, Jenny Szu-Chin;
Tong, Qiang;
Sun, Yuxiang;
Sheikh-Hamad, David

Publication type:

Article

Obesity and neuroinflammatory phenotype in mice lacking endothelial megalin.

Published in:

2017

By:

Bartolome, Fernando;
Antequera, Desiree;
Tavares, Eva;
Pascual, Consuelo;
Maldonado, Rosario;
Camins, Antoni;
Carro, Eva

Publication type:

journal article

Megalin-deficiency causes high myopia, retinal pigment epithelium-macromelanosomes and abnormal development of the ciliary body in mice.

Published in:

Cell & Tissue Research, 2014, v. 358, n. 1, p. 99, doi. 10.1007/s00441-014-1919-4

By:

Storm, Tina;
Heegaard, Steffen;
Christensen, Erik;
Nielsen, Rikke

Publication type:

Article

ARH directs megalin to the endocytic recycling compartment to regulate its proteolysis and gene expression.

Published in:

Journal of Cell Biology, 2013, v. 202, n. 1, p. 113, doi. 10.1083/jcb.201211110

By:

Mehul Shah;
Baterina Jr., Oscar Y.;
Taupin, Vanessa;
Farquhar, Marilyn G.

Publication type:

Article

Renal miR-148b is associated with megalin down-regulation in IgA nephropathy.

Published in:

Bioscience Reports, 2018, v. 38, n. 6, p. 1, doi. 10.1042/BSR20181578

By:

Lu Wen;
Zhanzheng Zhao;
Jing Xiao;
Zheng Wang;
Xiangfei He;
Henrik Birn

Publication type:

Article

Cadmium Complexed with β2-Microglubulin, Albumin and Lipocalin-2 rather than Metallothionein Cause Megalin:Cubilin Dependent Toxicity of the Renal Proximal Tubule.

Published in:

International Journal of Molecular Sciences, 2019, v. 20, n. 10, p. 2379, doi. 10.3390/ijms20102379

By:

Fels, Johannes;
Scharner, Bettina;
Zarbock, Ralf;
Zavala Guevara, Itzel Pamela;
Lee, Wing-Kee;
Barbier, Olivier C.;
Thévenod, Frank

Publication type:

Article

Angiotensin II Stimulation of DPP4 Activity Regulates Megalin in the Proximal Tubules.

Published in:

International Journal of Molecular Sciences, 2016, v. 17, n. 5, p. 780, doi. 10.3390/ijms17050780

By:

Aroor, Annayya;
Zuberek, Marcin;
Duta, Cornel;
Meuth, Alex;
Sowers, James R.;
Whaley-Connell, Adam;
Nistala, Ravi

Publication type:

Article

Nephropathology.

Published in:: Histopathology, 2012, v. 61, p. 168, doi. 10.1111/j.1365-2559.2012.04359_18.x
Publication type:: Article

The Endocytic Receptor Megalin and its Associated Proteins in Proximal Tubule Epithelial Cells.

Published in:

Membranes, 2014, v. 4, n. 3, p. 333, doi. 10.3390/membranes4030333

By:

Shankhajit De;
Shoji Kuwahara;
Akihiko Saito

Publication type:

Article

Upregulation of c-mip is closely related to podocyte dysfunction in membranous nephropathy.

Published in:

Kidney International, 2013, v. 83, n. 3, p. 414, doi. 10.1038/ki.2012.426

By:

Sendeyo, Kelhia;
Audard, Vincent;
Zhang, Shao-yu;
Fan, Qingfeng;
Bouachi, Khedidja;
Ollero, Mario;
Rucker-Martin, Catherine;
Gouadon, Elodie;
Desvaux, Dominique;
Bridoux, Franck;
Guellaën, Georges;
Ronco, Pierre;
Lang, Philippe;
Pawlak, Andre;
Sahali, Djillali

Publication type:

Article

Acute endotoxemia in mice induces downregulation of megalin and cubilin in the kidney.

Published in:

Kidney International, 2012, v. 82, n. 1, p. 53, doi. 10.1038/ki.2012.62

By:

Schreiber, Andrea;
Theilig, Franziska;
Schweda, Frank;
Höcherl, Klaus

Publication type:

Article

Urinary Iron Excretion is Associated with Urinary Full-Length Megalin and Renal Oxidative Stress in Chronic Kidney Disease.

Published in:

Kidney & Blood Pressure Research, 2018, v. 43, n. 2, p. 458, doi. 10.1159/000488470

By:

Nakatani, Shinya;
Nakatani, Ayumi;
Ishimura, Eiji;
Toi, Norikazu;
Tsuda, Akihiro;
Mori, Katsuhito;
Emoto, Masanori;
Hirayama, Yoshiaki;
Saito, Akihiko;
Inaba, Masaaki

Publication type:

Article

Missense Mutations in LRP5 Associated with High Bone Mass Protect the Mouse Skeleton from Disuse- and Ovariectomy-Induced Osteopenia.

Published in:

PLoS ONE, 2015, v. 10, n. 10, p. 1, doi. 10.1371/journal.pone.0140775

By:

Niziolek, Paul J.;
Bullock, Whitney;
Warman, Matthew L.;
Robling, Alexander G.

Publication type:

Article

Common Variants in LRP2 and COMT Genes Affect the Susceptibility of Gout in a Chinese Population.

Published in:

PLoS ONE, 2015, v. 10, n. 7, p. 1, doi. 10.1371/journal.pone.0131302

By:

Dong, Zheng;
Zhao, Dongbao;
Yang, Chengde;
Zhou, Jingru;
Qian, Qiaoxia;
Ma, Yanyun;
He, Hongjun;
Ji, Hengdong;
Yang, Yajun;
Wang, Xiaofeng;
Xu, Xia;
Pang, Yafei;
Zou, Hejian;
Jin, Li;
Wang, Jiucun

Publication type:

Article

Foxg1-Cre Mediated Lrp2 Inactivation in the Developing Mouse Neural Retina, Ciliary and Retinal Pigment Epithelia Models Congenital High Myopia.

Published in:

PLoS ONE, 2015, v. 10, n. 6, p. 1, doi. 10.1371/journal.pone.0129518

By:

Cases, Olivier;
Joseph, Antoine;
Obry, Antoine;
Santin, Mathieu D.;
Ben-Yacoub, Sirine;
Pâques, Michel;
Amsellem-Levera, Sabine;
Bribian, Ana;
Simonutti, Manuel;
Augustin, Sébastien;
Debeir, Thomas;
Sahel, José Alain;
Christ, Annabel;
de Castro, Fernando;
Lehéricy, Stéphane;
Cosette, Pascal;
Kozyraki, Renata

Publication type:

Article

Significance of Urinary Full-Length Megalin in Patients with IgA Nephropathy.

Published in:

PLoS ONE, 2014, v. 9, n. 12, p. 1, doi. 10.1371/journal.pone.0114400

By:

Seki, Takuto;
Asanuma, Katsuhiko;
Asao, Rin;
Nonaka, Kanae;
Sasaki, Yu;
Trejo, Juan Alejandro Oliva;
Kurosawa, Hiroyuki;
Hirayama, Yoshiaki;
Horikoshi, Satoshi;
Tomino, Yasuhiko;
Saito, Akihiko

Publication type:

Article

Adhesion and Invasion of Breast and Oesophageal Cancer Cells Are Impeded by Anti-LRP/LR-Specific Antibody IgG1-iS18.

Published in:

PLoS ONE, 2013, v. 8, n. 6, p. 1, doi. 10.1371/journal.pone.0066297

By:

Khumalo, Thandokuhle;
Reusch, Uwe;
Knackmuss, Stefan;
Little, Melvyn;
Veale, Robin B.;
Weiss, Stefan F. T.

Publication type:

Article

Receptor-Mediated Endocytosis of α-Galactosidase A in Human Podocytes in Fabry Disease.

Published in:

PLoS ONE, 2011, v. 6, n. 9, p. 1, doi. 10.1371/journal.pone.0025065

By:

Prabakaran, Thaneas;
Nielsen, Rikke;
Larsen, Jakob V.;
Sørensen, Søren S.;
Feldt-Rasmussen, Ulla;
Saleem, Moin A.;
Petersen, Claus M.;
Verroust, Pierre J.;
Christensen, Erik I.

Publication type:

Article

Megalin/LRP2 Expression Is Induced by Peroxisome Proliferator-Activated Receptor -Alpha and -Gamma: Implications for PPARs' Roles in Renal Function.

Published in:

PLoS ONE, 2011, v. 6, n. 2, p. 1, doi. 10.1371/journal.pone.0016794

By:

Cabezas, Felipe;
Lagos, Jonathan;
Céspedes, Carlos;
Vio, Carlos P.;
Bronfman, Miguel;
Marzolo, María-Paz

Publication type:

Article

Megalin mediates transepithelial albumin clearance from the alveolar space of intact rabbit lungs.

Published in:

Journal of Physiology, 2012, v. 590, n. 20, p. 5167, doi. 10.1113/jphysiol.2012.233403

By:

Buchäckert, Yasmin;
Rummel, Sebastian;
Vohwinkel, Christine U.;
Gabrielli, Nieves M.;
Grzesik, Benno A.;
Mayer, Konstantin;
Herold, Susanne;
Morty, Rory E.;
Seeger, Werner;
Vadász, István

Publication type:

Article

Genetic Variants and Associations of 25-Hydroxyvitamin D Concentrations With Major Clinical Outcomes.

Published in:

JAMA: Journal of the American Medical Association, 2012, v. 308, n. 18, p. 1898, doi. 10.1001/jama.2012.17304

By:

Levin, Gregory P.;
Robinson-Cohen, Cassianne;
de Boer, Ian H.;
Houston, Denise K.;
Lohman, Kurt;
Liu, Yongmei;
Kritchevsky, Stephen B.;
Cauley, Jane A.;
Tanaka, Toshiko;
Ferrucci, Luigi;
Bandinelli, Stefania;
Patel, Kushang V.;
Hagstrüm, Emil;
Michaëlsson, Karl;
Melhus, Håkan;
Wang, Thomas;
Wolt, Myles;
Psaty, Bruce M.;
Siscovick, David;
Kestenbaum, Bryan

Publication type:

Article

Soluble megalin is reduced in cerebrospinal fluid samples of Alzheimer's disease patients.

Published in:

Frontiers in Cellular Neuroscience, 2015, v. 9, p. 1, doi. 10.3389/fncel.2015.00134

By:

Spuch, Carlos;
Antequera, Desireé;
Pascual, Consuelo;
Abilleira, Soledad;
Blanco, María;
Moreno-Carretero, María José;
Romero-López, Jesús;
Ishida, Tetsuya;
Molina, Jose Antonio;
Villarejo, Alberto;
Bermejo-Pareja, Felix;
Carro, Eva

Publication type:

Article

Making a Dent in Dent Disease.

Published in:: Function, 2020, v. 1, n. 2, p. 1, doi. 10.1093/function/zqaa017
Publication type:: Article