Works matching DE "MCL1 protein"

Results: 22

Oncogenic BRAF signalling increases Mcl-1 expression in cutaneous metastatic melanoma.

Published in:

Experimental Dermatology, 2013, v. 22, n. 11, p. 767, doi. 10.1111/exd.12254

By:

McKee, Christopher S.;
Hill, David S.;
Redfern, Christopher P. F.;
Armstrong, Jane L.;
Lovat, Penny E.

Publication type:

Article

Mcl-1 rescues a glitch in the matrix.

Published in:

Nature Cell Biology, 2012, v. 14, n. 6, p. 563, doi. 10.1038/ncb2511

By:

Andersen, Joshua L.;
Kornbluth, Sally

Publication type:

Article

Deubiquitinase USP13 dictates MCL1 stability and sensitivity to BH3 mimetic inhibitors.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-017-02693-9

By:

Ying Jing;
Pengfei Ma;
Shengzhe Zhang;
Wen Di;
Guanglei Zhuang;
Meiying Zhang;
Xia Yin;
Zhenfeng Zhang;
Xiaojie Wang

Publication type:

Article

The VTLISFG motif in the BH1 domain plays a significant role in regulating the degradation of Mcl-1.

Published in:

FEBS Open Bio, 2014, v. 4, p. 147, doi. 10.1016/j.fob.2014.01.006

By:

Xiao, Kang;
Chen, Pengxuan;
Chang, Donald Choy

Publication type:

Article

The VTLISFG motif in the BH1 domain plays a significant role in regulating the degradation of Mcl‐1.

Published in:

FEBS Open Bio, 2014, v. 4, n. 1, p. 147, doi. 10.1016/j.fob.2014.01.006

By:

Xiao, Kang;
Chen, Pengxuan;
Chang, Donald Choy

Publication type:

Article

Rituximab-based pre-emptive treatment of molecular relapse in follicular and mantle cell lymphoma.

Published in:

Annals of Hematology, 2013, v. 92, n. 11, p. 1503, doi. 10.1007/s00277-013-1797-y

By:

Ferrero, Simone;
Monitillo, Luigia;
Mantoan, Barbara;
Barbero, Daniela;
Genuardi, Elisa;
Barbiero, Sara;
Bernocco, Elisa;
Caracciolo, Daniele;
Ruella, Marco;
Drandi, Daniela;
Zanni, Manuela;
Renna, Federica;
Lobetti Bodoni, Chiara;
Gueli, Angela;
Passera, Roberto;
Musto, Pellegrino;
Boccadoro, Mario;
Tarella, Corrado;
Ladetto, Marco

Publication type:

Article

Degradation of Mcl-1 through GSK-3β Activation Regulates Apoptosis Induced by Bufalin in Non-Small Cell Lung Cancer H1975 Cells.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2017, v. 41, n. 5, p. 2067, doi. 10.1159/000475438

By:

Xiao-hong Kang;
Jing-hang Zhang;
Qing-qin Zhang;
Yan-hui Cui;
Ying Wang;
Wei-zheng Kou;
Zhan-hui Miao;
Ping Lu;
Li-Fang Wang;
Zhen-ye Xu;
Fei Cao

Publication type:

Article

Targeting melanoma's MCL1 bias unleashes the apoptotic potential of BRAF and ERK1/2 pathway inhibitors.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-12409-w

By:

Sale, Matthew J.;
Minihane, Emma;
Monks, Noel R.;
Gilley, Rebecca;
Richards, Frances M.;
Schifferli, Kevin P.;
Andersen, Courtney L.;
Davies, Emma J.;
Vicente, Mario Aladren;
Ozono, Eiko;
Markovets, Aleksandra;
Dry, Jonathan R.;
Drew, Lisa;
Flemington, Vikki;
Proia, Theresa;
Jodrell, Duncan I.;
Smith, Paul D.;
Cook, Simon J.

Publication type:

Article

A novel BH3 mimetic efficiently induces apoptosis in melanoma cells through direct binding to anti-apoptotic Bcl-2 family proteins, including phosphorylated Mcl-1.

Published in:

Pigment Cell & Melanoma Research, 2015, v. 28, n. 2, p. 161, doi. 10.1111/pcmr.12325

By:

Liu, Yubo;
Xie, Mingzhou;
Song, Ting;
Sheng, Hongkun;
Yu, Xiaoyan;
Zhang, Zhichao

Publication type:

Article

Regulation of Mcl-1 by constitutive activation of NF-kappaB contributes to cell viability in human esophageal squamous cell carcinoma cells.

Published in:

BMC Cancer, 2014, v. 14, n. 1, p. 1, doi. 10.1186/1471-2407-14-98

By:

Haidan Liu;
Jinfu Yang;
Yunchang Yuan;
Zhenkun Xia;
Mingjiu Chen;
Li Xie;
Xiaolong Ma;
Jian Wang;
Sufeng Ouyang;
Qin Wu;
Fenglei Yu;
Xinmin Zhou;
Yifeng Yang;
Ya Cao;
Jianguo Hu;
Bangliang Yin

Publication type:

Article

Multiplex Analysis of Anti-Apoptotic BCL2 Family and Caspase 3 Activation by Microbead Arrays.

Published in:

Assay & Drug Development Technologies, 2014, v. 12, n. 3, p. 190, doi. 10.1089/adt.2013.557

By:

Lam, Lloyd T.;
Roberts-Rapp, Lisa

Publication type:

Article

MCL-1 is modulated in Crohn's disease fibrosis by miR-29b via IL-6 and IL-8.

Published in:

Cell & Tissue Research, 2017, v. 368, n. 2, p. 325, doi. 10.1007/s00441-017-2576-1

By:

Nijhuis, Anke;
Curciarello, Renata;
Mehta, Shameer;
Feakins, Roger;
Bishop, Cleo;
Lindsay, James;
Silver, Andrew

Publication type:

Article

Overexpression of Mcl-1L Splice Variant Is Associated with Poor Prognosis and Chemoresistance in Oral Cancers.

Published in:

PLoS ONE, 2014, v. 9, n. 11, p. 1, doi. 10.1371/journal.pone.0111927

By:

Palve, Vinayak;
Mallick, Sanchita;
Ghaisas, Gauri;
Kannan, Sadhana;
Teni, Tanuja

Publication type:

Article

Curcumin Significantly Enhances Dual PI3K/Akt and mTOR Inhibitor NVP-BEZ235-Induced Apoptosis in Human Renal Carcinoma Caki Cells through Down-Regulation of p53-Dependent Bcl-2 Expression and Inhibition of Mcl-1 Protein Stability.

Published in:

PLoS ONE, 2014, v. 9, n. 4, p. 1, doi. 10.1371/journal.pone.0095588

By:

Seo, Bo Ram;
Min, Kyoung-jin;
Cho, Il Je;
Kim, Sang Chan;
Kwon, Taeg Kyu

Publication type:

Article

Circumvention of Mcl-1-Dependent Drug Resistance by Simultaneous Chk1 and MEK1/2 Inhibition in Human Multiple Myeloma Cells.

Published in:

PLoS ONE, 2014, v. 9, n. 3, p. 1, doi. 10.1371/journal.pone.0089064

By:

Pei, Xin-Yan;
Dai, Yun;
Felthousen, Jessica;
Chen, Shuang;
Takabatake, Yukie;
Zhou, Liang;
Youssefian, Leena E.;
Sanderson, Michael W.;
Bodie, Wesley W.;
Kramer, Lora B.;
Orlowski, Robert Z.;
Grant, Steven

Publication type:

Article

BAD Dephosphorylation and Decreased Expression of MCL-1 Induce Rapid Apoptosis in Prostate Cancer Cells.

Published in:

PLoS ONE, 2013, v. 8, n. 9, p. 1, doi. 10.1371/journal.pone.0074561

By:

Yancey, Dana;
Nelson, Kyle C.;
Baiz, Daniele;
Hassan, Sazzad;
Flores, Anabel;
Pullikuth, Ashok;
Karpova, Yelena;
Axanova, Linara;
Moore, Victoria;
Sui, Guangchao;
Kulik, George

Publication type:

Article

βArrestin-1 and Mcl-1 Modulate Self-Renewal Growth of Cancer Stem-Like Side-Population Cells in Non-Small Cell Lung Cancer.

Published in:

PLoS ONE, 2013, v. 8, n. 2, p. 1, doi. 10.1371/journal.pone.0055982

By:

Singh, Sandeep;
Bora-Singhal, Namrata;
Kroeger, Jodi;
Laklai, Hanane;
Chellappan, Srikumar P.

Publication type:

Article

Obatoclax is a direct and potent antagonist of membrane-restricted Mcl-1 and is synthetic lethal with treatment that induces Bim.

Published in:

BMC Cancer, 2015, v. 15, n. 1, p. 1, doi. 10.1186/s12885-015-1582-5

By:

Mai Nguyen;
Cencic, Regina;
Ertel, Franziska;
Bernier, Cynthia;
Pelletier, Jerry;
Roulston, Anne;
Silvius, John R.;
Shore, Gordon C.

Publication type:

Article

Gfi-1 inhibits proliferation and colony formation of p210BCR/ABL-expressing cells via transcriptional repression of STAT 5 and Mcl-1.

Published in:

Leukemia (08876924), 2012, v. 26, n. 7, p. 1555, doi. 10.1038/leu.2012.19

By:

Soliera, A R;
Mariani, S A;
Audia, A;
Lidonnici, M R;
Addya, S;
Ferrari-Amorotti, G;
Cattelani, S;
Manzotti, G;
Fragliasso, V;
Peterson, L;
Perini, G;
Holyoake, T L;
Calabretta, B

Publication type:

Article

Evaluation and critical assessment of putative MCL-1 inhibitors.

Published in:

Cell Death & Differentiation, 2013, v. 20, n. 11, p. 1475, doi. 10.1038/cdd.2013.79

By:

Varadarajan, S;
Vogler, M;
Butterworth, M;
Dinsdale, D;
Walensky, L D;
Cohen, G M

Publication type:

Article

Seeking a MCL-1 inhibitor.

Published in:

Cell Death & Differentiation, 2013, v. 20, n. 11, p. 1440, doi. 10.1038/cdd.2013.114

By:

Brumatti, G;
Ekert, P G

Publication type:

Article

Targeting Mcl-1 enhances DNA replication stress sensitivity to cancer therapy.

Published in:

2018

By:

Guo Chen;
Magis, Andrew T.;
Ke Xu;
Dongkyoo Park;
Yu, David S.;
Owonikoko, Taofeek K.;
Sica, Gabriel L.;
Satola, Sarah W.;
Ramalingam, Suresh S.;
Curran, Walter J.;
Doetsch, Paul W.;
Xingming Deng;
Chen, Guo;
Xu, Ke;
Park, Dongkyoo;
Deng, Xingming

Publication type:

journal article