Works matching DE "MACROPHAGE activation"

Results: 2104

CircABCA1 promotes ccRCC by reprogramming cholesterol metabolism and facilitating M2 macrophage polarization through IGF2BP3-mediated stabilization of SCARB1 mRNA.

Published in:

Molecular Cancer, 2025, v. 24, n. 1, p. 1, doi. 10.1186/s12943-025-02398-4

By:

Ning, Hao;
Jiang, Yan;
Li, Binbin;
Ren, Junwu;
Wang, Cong;
Wei, Ling;
Li, Linfei;
Ran, Ai;
Li, Zuozhang;
Li, Jiao;
Li, Wei;
Wang, Yongquan;
Xiao, Bin

Publication type:

Article

Opposing regulation of TNF responses by IFN-γ and a PGE2-cAMP axis that is apparent in rheumatoid and immune checkpoint inhibitor-induced arthritis human IL-1β+ macrophages.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.104367

By:

Sokhi, Upneet K.;
Ruoxi Yuan;
Mishra, Bikash;
Chinenov, Yurii;
Singaraju, Anvita;
Chan, Karmela K.;
Bass, Anne;
Bell, Richard D.;
Donlin, Laura;
Ivashkiv, Lionel B.

Publication type:

Article

Integration of single-cell RNA and bulk RNA sequencing revealed malignant ductal cell heterogeneity and prognosis signatures in pancreatic cancer.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1579184

By:

Du, Haiyang;
Si, Gao;
Si, Jiqing;
Song, Xuejie;
Si, Fuchun

Publication type:

Article

Cimifugin ameliorates ulcerative colitis-related lung injury by modulating the JAK1/STAT1 signaling pathway and macrophage M1 polarization.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1551892

By:

Wang, Guanyuan;
Yang, Fan;
Zang, Guodong;
Shen, Ning;
Huang, Lina;
Ma, Zhaotian;
Li, Ming

Publication type:

Article

Prognostic and tumor microenvironmental features of gastric cancer revealed by macrophage polarization and protein lactylation-related genes.

Published in:

Frontiers in Genetics, 2025, p. 1, doi. 10.3389/fgene.2025.1541489

By:

Xu, Zifan;
Lei, Zi;
Peng, Shilan;
Li, Sha;
Kong, Dehui;
Duan, Hongqiong;
Zhang, Man;
Su, Guomiao;
Pan, Guoqing

Publication type:

Article

Single-cell RNA sequencing reveals the effects of mental stress on mouse mammary tumors and the tumor microenvironment.

Published in:

Cell Death Discovery, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41420-025-02619-1

By:

Liu, Pengfei;
Ma, Wenjing;
Wang, Tao;
Lü, Jinhui;
Wang, Weizhong;
Wang, Yixing;
Tang, Qifan;
Di, Jing;
Bischof, Evelyne;
Zhao, Qian;
Yu, Zuoren

Publication type:

Article

Exo-miR-1911-5p regulates ferroptosis to promote macrophages M2 polarization-mediated gastric cancer cisplatin resistance via MYB/AKR1B10/ACC.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-08441-w

By:

Kong, Zihao;
Zhang, Min;
Yuan, Hui;
Liu, Jiahao;
Sang, Huaiming;
Zhao, Ping;
Xu, Miao;
Zhu, Chuanlong;
Zhang, Guoxin

Publication type:

Article

Narirutin treatment accelerates the process of diabetic wound repair by regulating phenotype switching of macrophages through affecting metabolic reprogramming.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1614967

By:

Liu, Liang;
Wang, Han;
Zhou, Juan;
Lu, Jing;
Zhang, Yan;
Liu, Haiyan;
Lu, Li

Publication type:

Article

circ-0001875 downregulation is associated with M1 macrophage activation and lung inflammation in severe asthma.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1601272

By:

Liu, Gege;
Cao, Jiahao;
Lin, Yiyan;
Long, Bingyu;
Su, Yanyu;
Qiu, Guiqiang;
Jiang, Chi;
Wang, Yue;
Zhao, Xuanna;
Huang, Dan;
Wu, Dong

Publication type:

Article

CX3CL1 promotes M1 macrophage polarization and osteoclast differentiation via NSUN5-mediated m5C modification.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-11046-2

By:

Deng, Zhibin;
Zhong, Wei

Publication type:

Article

Development of Immune-Regulatory Pseudo-Protein-Coated Iron Oxide Nanoparticles for Enhanced Treatment of Triple-Negative Breast Tumor.

Published in:

Nanomaterials (2079-4991), 2025, v. 15, n. 13, p. 1006, doi. 10.3390/nano15131006

By:

Ji, Ying;
Li, Juan;
Ma, Li;
Wang, Zhijie;
Du, Bochu;
Kwan, Hiu Yee;
Bian, Zhaoxiang;
Chu, Chih-Chang

Publication type:

Article

LncRNA MEG3 suppresses prostate cancer progression by mediating macrophage polarization via the miR-148a-3p/ARRDC3 signaling axis.

Published in:

Carcinogenesis, 2025, v. 46, n. 2, p. 1, doi. 10.1093/carcin/bgaf009

By:

Luo, Jinguang;
Tao, Huaixiang;
Chen, Long;
Hu, Hao;
Mao, Likai;
Guan, Han

Publication type:

Article

Transcriptome reveals the landscape of alveolar macrophages exposed to combined hypoxia with cigarette smoke extract.

Published in:

Respiratory Research, 2025, v. 26, n. 1, p. 1, doi. 10.1186/s12931-025-03303-9

By:

Liu, Qing;
Zhang, Yushi;
Duan, Ruirui;
Li, Wanheng;
Hou, Xuan;
Chen, Yiling;
Li, Baicun;
Yang, Ting

Publication type:

Article

MTMR14 depletion aggravates intrapulmonary inflammation and emphysema in experimental COPD through activating macrophage M1 polarization.

Published in:

Respiratory Research, 2025, v. 26, n. 1, p. 1, doi. 10.1186/s12931-025-03293-8

By:

Zhang, Jiaheng;
Zhan, Yuan;
Deng, Zhesong;
Chen, Shanshan;
Yang, Ruonan;
Zhang, Yating;
Fu, Hao;
Huang, Qian;
Wu, Jixing;
Gu, Yiya;
Xie, Jungang

Publication type:

Article

Anti atherosclerosis effect and mechanism of a novel curcumin analogue CACN136: regulating macrophage M1/M2 polarization and lipid metabolism.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1632647

By:

Zhao, Qianjiao;
Zhong, Yueting;
Li, Zheng;
Tang, Jia;
Pi, Chao;
Zheng, Wenwu;
Shi, Peng;
Zuo, Ying;
Jiang, Jun;
Yang, Yan;
Chu, Shifeng;
Wei, Yumeng;
Zhao, Ling

Publication type:

Article

NR4A3 potentials M1-like macrophage polarization to facilitate anti-tumor immune responses in breast cancer.

Published in:

NPJ Breast Cancer, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41523-025-00785-0

By:

Qian, Yi-yu;
Jin, Ning;
Rao, Shan-shan;
Wang, Ya;
Li, Xin;
Pan, Wen;
Huang, Pu;
Wang, Si-yuan;
Li, Ping-fei;
Lv, Yan-kai;
Gao, Qing-lei;
Xia, Yu

Publication type:

Article

Macrophages regulate angiogenesis-osteogenesis coupling induced by mechanical loading through the Piezo1 pathway.

Published in:

Journal of Bone & Mineral Research, 2025, v. 40, n. 6, p. 725, doi. 10.1093/jbmr/zjae198

By:

Liu, Hongzhi;
Zhou, Hang;
Fan, Yuanhao;
Li, Jiawei;
Guo, Ziyu;
Xu, Qiuchi;
Liu, Yang;
Gao, Kun;
Ait Lahcine, Neima;
Zhang, Jianing;
Zhou, Jingjing;
Guo, Fengjin;
Liu, Chao

Publication type:

Article

The Chemical Profiling and Immunological Activity of Polysaccharides from the Rhizome of Imperata cylindrica Using Hot Water Extraction.

Published in:

Molecules, 2025, v. 30, n. 12, p. 2635, doi. 10.3390/molecules30122635

By:

Sun, Meng-Ge;
Chen, Jia-Jie;
Xu, Jia-Min;
Chen, Wei;
Chen, Xiao-Bing;
Yang, Dong-Sheng

Publication type:

Article

Indole-3-Carbinol Enhances Alternative Activation of Macrophages via AHR Pathway and Glucose Transporter Regulation.

Published in:

Immuno, 2025, v. 5, n. 2, p. 15, doi. 10.3390/immuno5020015

By:

Omrani, Delara;
Mohammadi, Saeed;
Malekzadeh, Moein;
Saeidi, Mohsen;
Seyedhosseini, Fakhri Sadat;
Al-Harrasi, Ahmed;
Yazdani, Yaghoub

Publication type:

Article

Macrophage activation marker, soluble CD163, is an independent predictor of short-term mortality in patients with cirrhosis and bacterial infection.

Published in:

Liver International, 2016, v. 36, n. 11, p. 1628, doi. 10.1111/liv.13133

By:

Tornai, Tamas;
Vitalis, Zsuzsanna;
Sipeki, Nora;
Dinya, Tamas;
Tornai, David;
Antal ‐ Szalmas, Peter;
Karanyi, Zsolt;
Tornai, Istvan;
Papp, Maria

Publication type:

Article

The macrophage activation marker sCD163 is associated with morphological disease stages in patients with non-alcoholic fatty liver disease.

Published in:

Liver International, 2016, v. 36, n. 10, p. 1549, doi. 10.1111/liv.13150

By:

Kazankov, Konstantin;
Barrera, Francisco;
Møller, Holger Jon;
Rosso, Chiara;
Bugianesi, Elisabetta;
David, Ezio;
Ibrahim Kamal Jouness, Ramy;
Esmaili, Saeed;
Eslam, Mohammed;
McLeod, Duncan;
Bibby, Bo Martin;
Vilstrup, Hendrik;
George, Jacob;
Grønbæk, Henning

Publication type:

Article

Alcohol withdrawal alleviates adipose tissue inflammation in patients with alcoholic liver disease.

Published in:

Liver International, 2015, v. 35, n. 3, p. 967, doi. 10.1111/liv.12575

By:

Voican, Cosmin S.;
Njiké‐Nakseu, Micheline;
Boujedidi, Hédia;
Barri‐Ova, Nadège;
Bouchet‐Delbos, Laurence;
Agostini, Hélène;
Maitre, Sophie;
Prévot, Sophie;
Cassard‐Doulcier, Anne‐Marie;
Naveau, Sylvie;
Perlemuter, Gabriel

Publication type:

Article

New venues for the treatment of hepatitis: pharmacological or genetical interventions of macrophage polarization by targeting Ang/Tie-2 axis.

Published in:

Liver International, 2014, v. 34, n. 1, p. 163, doi. 10.1111/liv.12293

By:

Zhou, Dexi;
Lin, Zhen;
Huang, Cheng;
Li, Jun

Publication type:

Article

Hepcidin response to acute iron intake and chronic iron loading in dysmetabolic iron overload syndrome.

Published in:

Liver International, 2011, v. 31, n. 7, p. 994, doi. 10.1111/j.1478-3231.2011.02520.x

By:

Trombini, Paola;
Paolini, Valentina;
Pelucchi, Sara;
Mariani, Raffaella;
Nemeth, Elizabeta;
Ganz, Tomas;
Piperno, Alberto

Publication type:

Article

Effect of Fonsecaea monophora on the Polarization of THP-1 Cells to Macrophages.

Published in:

Mycopathologia, 2020, v. 185, n. 3, p. 467, doi. 10.1007/s11046-020-00444-x

By:

Qin, Jinglin;
Zhang, Jing;
Shi, Minglan;
Xi, Liyan;
Zhang, Junmin

Publication type:

Article

The Critical Role of Notch1-TLR 4 Signaling in the Inflammatory and Fungicidal Activity of Macrophages Against Paracoccidioides brasiliensis Strain Pb18.

Published in:

Mycopathologia, 2017, v. 182, n. 9/10, p. 797, doi. 10.1007/s11046-017-0154-4

By:

Romera, Lavínia;
Kaihami, Gilberto;
Jannuzzi, Grasielle;
Almeida, José;
Almeida, Sandro

Publication type:

Article

Response of Cytokines and Hydrogen Peroxide to Sporothrix schenckii Exoantigen in Systemic Experimental Infection.

Published in:

Mycopathologia, 2016, v. 181, n. 3/4, p. 207, doi. 10.1007/s11046-015-9966-2

By:

Maia, Danielle;
Gonçalves, Amanda;
Ferreira, Lucas;
Manente, Francine;
Portuondo, Deivys;
Vellosa, José;
Polesi, Marisa;
Batista-Duharte, Alexander;
Carlos, Iracilda

Publication type:

Article

Killing of Paracoccidioides brasiliensis yeast cells by IFN-γ and TNF-α activated murine peritoneal macrophages: evidence of H<sub>2</sub>O<sub>2</sub> and NO effector mechanisms.

Published in:

Mycopathologia, 2008, v. 166, n. 1, p. 17, doi. 10.1007/s11046-007-9046-3

By:

Ana Moreira;
Luciane Dias-Melicio;
Maria Peraçoli;
Sueli Calvi;
Angela Victoriano de Campos Soares

Publication type:

Article

Mangiferin: A natural bioactive immunomodulating glucosylxanthone with potential against cancer and rheumatoid arthritis.

Published in:

Journal of Biochemical & Molecular Toxicology, 2024, v. 38, n. 7, p. 1, doi. 10.1002/jbt.23765

By:

Akkewar, Ashish Sunil;
Mishra, KM Abha;
Sethi, Kalyan K.

Publication type:

Article

Evidence for M2 macrophage activation in patients with enthesitis-related arthritis category of juvenile idiopathic arthritis.

Published in:

Clinical Rheumatology, 2019, v. 38, n. 6, p. 1715, doi. 10.1007/s10067-018-04408-x

By:

Bhattacharya, Shruti;
Yadav, Akhilesh;
Aggarwal, Amita

Publication type:

Article

Macrophage activation syndrome in a patient with axial spondyloarthritis on adalimumab.

Published in:

Clinical Rheumatology, 2019, v. 38, n. 2, p. 603, doi. 10.1007/s10067-018-4387-5

By:

Baker, Rahaf;
Liew, Jean W.;
Simonson, Paul D.;
Soma, Lori A.;
Starkebaum, Gordon

Publication type:

Article

Tocilizumab in the treatment of the adult-onset Still's disease: current clinical evidence.

Published in:

Clinical Rheumatology, 2013, v. 32, n. 1, p. 141, doi. 10.1007/s10067-012-2105-2

By:

Boysson, Hubert;
Février, Jérome;
Nicolle, Amélie;
Auzary, Christophe;
Geffray, Loïk

Publication type:

Article

Clinical analysis of macrophage activation syndrome in pediatric patients with autoimmune diseases.

Published in:

Clinical Rheumatology, 2012, v. 31, n. 8, p. 1223, doi. 10.1007/s10067-012-1998-0

By:

Lin, Cheng-I;
Yu, Hsin-Hui;
Lee, Jyh-Hong;
Wang, Li-Chieh;
Lin, Yu-Tsan;
Yang, Yao-Hsu;
Chiang, Bor-Luen

Publication type:

Article

Ankylosing spondylitis presenting with macrophage activation syndrome.

Published in:

Clinical Rheumatology, 2007, v. 26, n. 11, p. 1929, doi. 10.1007/s10067-007-0538-9

By:

Yin-Jun Lou;
Jie Jin;
Wen-Yuan Mai

Publication type:

Article

Hemophagocytic syndrome in one patient with adult-onset Still’s disease.

Published in:

2007

By:

Pamuk, Ömer;
Pamuk, Gülsüm;
Usta, Ufuk;
Çakir, Necati

Publication type:

Report

Hemophagocytic syndrome as one of main manifestations in untreated systemic lupus erythematosus: two case reports and literature review.

Published in:

2007

By:

Jie Qian;
Cheng-De Yang

Publication type:

Report

Subcutaneous panniculitis-like T-cell lymphoma misdiagnosed as lupus erythematosus panniculitis.

Published in:

Clinical Rheumatology, 2007, v. 26, n. 2, p. 244, doi. 10.1007/s10067-005-0125-x

By:

Gonzalez, Estrella Garcia;
Selvi, Enrico;
Lorenzini, Sauro;
Maggio, Roberta;
Mannucci, Susanna;
Galeazzi, Mauro;
Marcolongo, Roberto

Publication type:

Article

Essential role of Toll-like receptor 2 in macrophage activation by glycogen.

Published in:

Glycobiology, 2012, v. 22, n. 1, p. 146, doi. 10.1093/glycob/cwr122

By:

Kakutani, Ryo;
Adachi, Yoshiyuki;
Takata, Hiroki;
Kuriki, Takashi;
Ohno, Naohito

Publication type:

Article

Single cell analysis and bioinformatics reveal pyroptosis mechanisms in hepatocellular carcinoma.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02907-3

By:

Luo, Wei;
JunxiaWang;
Wang, Hongfei;
Liu, Fei;
Yang, Taiwei;
Wu, Zhongjun;
Guo, Wubin

Publication type:

Article

SERPINA1 is a new frontier in cancer immunotherapy and drug targeting by pan-cancer analysis.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02832-5

By:

Fu, Chen;
Hu, Yanyun;
Yang, Lei;
Sun, Weifeng

Publication type:

Article

Glutamate promotes triple-negative breast cancer development through IRE1α/XBP1-mediated macrophage polarization: mechanism insights and therapy.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02790-y

By:

Wang, Hao;
Sun, Jifeng;
Jiang, Zhansheng;
Tong, Zhongsheng;
Wang, Chen

Publication type:

Article

PTTG1 promotes M2 macrophage polarization via the cGMP-PKG signaling pathway and facilitates EMT progression in human epithelial ovarian cancer cells.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02512-4

By:

Tian, Liang;
Liu, Liyun;
Wang, Chunlou;
Kong, Yan;
Miao, Zhigang;
Yao, Qing;
Zhang, He;
Li, Yuehong

Publication type:

Article

Acinar cells modulate the tumor microenvironment through the promotion of M1 macrophage polarization via macrophage endocytosis in pancreatic cancer.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02244-5

By:

Ma, Congjia;
Zhu, Wenbo;
Hu, Xiulin;
Wu, Deli;
Zhao, Xintong;
Du, Yiqi;
Kong, Xiangyu

Publication type:

Article

Applying integrated transcriptome and single-cell sequencing analysis to develop a prognostic signature based on M2-like tumor-associated macrophages for breast cancer.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02161-7

By:

Xu, Yanghaochen;
Lin, Peiyan;
Zhu, Ye;
Zhang, Qing;
Zhou, Jinhong

Publication type:

Article

Matrix-bound nanovesicle-associated IL-33 supports functional recovery after skeletal muscle injury by initiating a pro-regenerative macrophage phenotypic transition.

Published in:

NPJ Regenerative Medicine, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41536-024-00346-2

By:

Bartolacci, J. G.;
Behun, M. N.;
Warunek, J. P.;
Li, T.;
Sahu, A.;
Dwyer, G. K.;
Lucas, A.;
Rong, J.;
Ambrosio, F.;
Turnquist, H. R.;
Badylak, S. F.

Publication type:

Article

BHLHE40 contributes to allergic asthma progression in mice through NRTN downregulation in macrophages.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-08288-1

By:

Dai, Bing;
Chen, Li;
Li, Xiaowen;
Zhou, Qianlan;
Zhang, Qinzhen;
Han, Lina;
Shen, Wenxin;
Chang, Qing;
Zhao, Yuhong;
Liu, Si;
Shan, Lishen

Publication type:

Article

IL-33/ST2 drives inflammatory pain via CCL2 signaling and activation of TRPV1 and TRPM8.

Published in:

Communications Biology, 2025, p. 1, doi. 10.1038/s42003-025-08119-3

By:

Wang, Linjie;
Zhang, Jingyun;
Qiu, Shijuan;
Huang, Ruizhen;
Wang, Yuge;
Wang, Yuting;
Li, Mingyu;
Ye, Qingqing;
Zhang, Sibo;
Qi, Zhenhua;
Cao, Lan;
Li, Guohao;
An, Yajie;
Xie, Denghui;
Mi, Wenli;
Wang, Huaqiao;
Luo, Tao;
Xie, Jingdun;
Huang, Junting

Publication type:

Article

PKM2-mediated STAT3 phosphorylation promotes acute liver failure via regulating NLRP3-dependent pyroptosis.

Published in:

Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-07227-w

By:

Yu, Songman;
Pei, Siya;
Zhang, Min;
Gao, Shang;
Chen, Jun;
Duan, Lihua;
Hu, En;
Wang, Yang;
Huang, Yan

Publication type:

Article

MicroRNAs modulate the noncanonical transcription factor NF-κB pathway by regulating expression of the kinase IKKα during macrophage differentiation.

Published in:

Nature Immunology, 2010, v. 11, n. 9, p. 799, doi. 10.1038/ni.1918

By:

Tao Li;
Morgan, Michael J;
Choksi, Swati;
Yan Zhang;
You-Sun Kim;
Zheng-gang Liu

Publication type:

Article

IAPP boosts islet macrophage IL-1 in type 2 diabetes.

Published in:

Nature Immunology, 2010, v. 11, n. 10, p. 881, doi. 10.1038/ni1010-881

By:

Mandrup-Poulsen, Thomas

Publication type:

Article