Works matching DE "LYSOSOMES"

Results: 4743

The dilemma: Does tissue expression of cathepsin D reflect tumor malignancy? The question: Does the assay truly mirror cathepsin D mis-function in the tumor?

Published in:

Cancer Biomarkers, 2011, v. 7, n. 1, p. 47, doi. 10.3233/CBM-2010-0143

By:

Nicotra, Giuseppina;
Castino, Roberta;
Follo, Carlo;
Peracchio, Claudia;
Valente, Guido;
Isidoro, Ciro

Publication type:

Article

Deciphering the relationship between sarcopenia and aging: A combined text mining and bioinformatics approach.

Published in:

Geriatrics & Gerontology International, 2025, v. 25, n. 6, p. 806, doi. 10.1111/ggi.70042

By:

Kamihara, Takahiro;
Omura, Takuya;
Shimizu, Atsuya

Publication type:

Article

Regulatory Mechanisms and Therapeutic Targeting of PD-L1 Trafficking and Stability in Cancer Immunotherapy.

Published in:

Cancers, 2025, v. 17, n. 11, p. 1747, doi. 10.3390/cancers17111747

By:

Mani, Muralidharan;
Park, Jeong Woo;
Martin, Thomas F. J.

Publication type:

Article

Exploring Exosome Contributions to Gouty Arthritis: A Proteomics and Experimental Study.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 11, p. 5320, doi. 10.3390/ijms26115320

By:

Lu, Chengjin;
Yang, Xiaoxiong;
Wang, Xue;
Wang, Yu;
Zhang, Bing;
Lin, Zhijian

Publication type:

Article

Broken Balance: Emerging Cross-Talk Between Proteostasis and Lipostasis in Neurodegenerative Diseases.

Published in:

Cells (2073-4409), 2025, v. 14, n. 11, p. 845, doi. 10.3390/cells14110845

By:

Tittelmeier, Jessica;
Nussbaum-Krammer, Carmen

Publication type:

Article

Decoding extracellular matrix–lysosome cross-talk and its implications for neurodegenerative diseases.

Published in:

Science Signaling, 2025, v. 18, n. 890, p. 1, doi. 10.1126/scisignal.adt1936

By:

Yang, Qinghu;
Ma, Huan;
Yang, Liang;
Jiang, Ming;
Liu, Xia;
Bai, Zhantao

Publication type:

Article

Multi-omics analysis and single-cell sequencing revealed the lysosome associated molecular subtypes and prognostic model development of papillary thyroid carcinoma.

Published in:

PLoS ONE, 2025, v. 20, n. 6, p. 1, doi. 10.1371/journal.pone.0325486

By:

Zhang, Jianhua;
Yue, Kai;
Wu, Yansheng;
Jing, Chao;
Wang, Xudong

Publication type:

Article

Lysosomal TMEM165 controls cellular ion homeostasis and survival by mediating lysosomal Ca2+ import and H+ efflux.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-60349-5

By:

Chen, Ran;
Liu, Bin;
Jaślan, Dawid;
Kucej, Lucija;
Kudrina, Veronika;
Warnke, Belinda;
Klingl, Yvonne E.;
Petrauskas, Arnas;
Castro, Sandra Prat;
Maeda, Kenji;
Grimm, Christian;
Jäättelä, Marja

Publication type:

Article

NEMF-mediated CAT tailing facilitates translocation-associated quality control.

Published in:

Journal of Cell Biology, 2025, v. 224, n. 6, p. 1, doi. 10.1083/jcb.202408199

By:

Ennis, Amanda;
Lihui Wang;
Yue Xu;
Saidi, Layla;
Xiaorong Wang;
Clinton Yu;
Sijung Yun;
Lan Huang;
Yihong Ye

Publication type:

Article

Sorting nexin 10 regulates lysosomal ionic homeostasis via ClC-7 by controlling PI(3,5)P2.

Published in:

Journal of Cell Biology, 2025, v. 224, n. 6, p. 1, doi. 10.1083/jcb.202408174

By:

Jing Ze Wu;
Pemberton, Joshua G.;
Shin Morioka;
Junko Sasaki;
Bablani, Priya;
Takehiko Sasaki;
Balla, Tamas;
Grinstein, Sergio;
Freeman, Spencer A.

Publication type:

Article

Targeting Autophagy as a Strategy for Developing New Host-Directed Therapeutics Against Nontuberculous Mycobacteria.

Published in:

Pathogens, 2025, v. 14, n. 5, p. 472, doi. 10.3390/pathogens14050472

By:

Wang, Jia;
Lee, Sunhee

Publication type:

Article

Agonist-Triggered Ca2+ Release From Functionally Connected Endoplasmic Reticulum and Lysosomal Ca2+ Stores in bEND.3 Endothelial Cells.

Published in:

Physiological Research, 2025, v. 74, n. 2, p. 249, doi. 10.33549/physiolres.935472

By:

Cing-Yu CHEN;
Yu-Jen CHEN;
Cheng-An WANG;
Chen-Hsiu LIN;
Jong-Shiuan YEH;
CHAN, Paul;
Lian-Ru SHIAO;
Yuk-Man LEUNG

Publication type:

Article

Deciphering tuberculosis: lysosome-centric insights into pathogenesis and therapies.

Published in:

Frontiers in Cellular & Infection Microbiology, 2025, p. 1, doi. 10.3389/fcimb.2025.1582037

By:

Bao, Cui;
Zhang, Yuanyuan;
Feng, Jiao;
Hong, Xiuwen;
Gao, Nan;
Feng, Ganzhu

Publication type:

Article

Supramolecular Assembly of Water‐Soluble Platinum(II) Complexes: From Emission Modulation to Cell Imaging in Specific Organelles.

Published in:

Chemistry - A European Journal, 2025, v. 31, n. 30, p. 1, doi. 10.1002/chem.202404432

By:

Rex, Tobias;
Mößer, Theresa;
Vilela, Raquel R. C.;
Hepp, Alexander;
Grashoff, Carsten;
Strassert, Cristian A.

Publication type:

Article

Effects of maternal liver abnormality on in vitro maturation of bovine oocytes.

Published in:

Zygote, 2025, v. 33, n. 1, p. 32, doi. 10.1017/S0967199424000352

By:

Ashibe, Shiori;
Kobayashi, Yui;
Toishikawa, Shusuke;
Nagao, Yoshikazu

Publication type:

Article

Coxiella burnetii as a model system for understanding host immune response against obligate intracellular, vacuolar pathogens.

Published in:

PLoS Pathogens, 2025, v. 21, n. 5, p. 1, doi. 10.1371/journal.ppat.1013071

By:

Sasikala, Akhila;
Prakash, Chandhana;
Valli Ramamoorthy, Mullai;
Ganesan, Sandhya

Publication type:

Article

Homozygosity for the p.K136E mutation in the SLC17A5 gene as cause of an Italian severe Salla disease.

Published in:

Neurogenetics, 2005, v. 6, n. 4, p. 195, doi. 10.1007/s10048-005-0011-3

By:

Biancheri, R.;
Rossi, A.;
Verbeek, H.;
Schot, R.;
Corsolini, F.;
Assereto, S.;
Mancini, G.;
Verheijen, F.;
Minetti, C.;
Filocamo, M.

Publication type:

Article

Structural basis of ubiquitin recognition by mammalian Eap45 GLUE domain.

Published in:

Nature Structural & Molecular Biology, 2006, v. 13, n. 11, p. 1031, doi. 10.1038/nsmb1163

By:

Hirano, Satoshi;
Suzuki, Nobuhiro;
Slagsvold, Thomas;
Kawasaki, Masato;
Trambaiolo, Daniel;
Kato, Ryuichi;
Stenmark, Harald;
Wakatsuki, Soichi

Publication type:

Article

The retromer subunit Vps26 has an arrestin fold and binds Vps35 through its C-terminal domain.

Published in:

Nature Structural & Molecular Biology, 2006, v. 13, n. 6, p. 540, doi. 10.1038/nsmb1103

By:

Shi, Hang;
Rojas, Raul;
Bonifacino, Juan S;
Hurley, James H

Publication type:

Article

Double-sided ubiquitin binding of Hrs-UIM in endosomal protein sorting.

Published in:

Nature Structural & Molecular Biology, 2006, v. 13, n. 3, p. 272, doi. 10.1038/nsmb1051

By:

Hirano, Satoshi;
Kawasaki, Masato;
Ura, Hideaki;
Kato, Ryuichi;
Raiborg, Camilla;
Stenmark, Harald;
Wakatsuki, Soichi

Publication type:

Article

Opinion: The Trypanosoma cruzi–host-cell interplay: location, invasion, retention.

Published in:

Nature Reviews Microbiology, 2005, v. 3, n. 10, p. 819, doi. 10.1038/nrmicro1249

By:

Andrade, Luciana O.;
Andrews, Norma W.

Publication type:

Article

Protozoan parasites: Reversible entry.

Published in:

Nature Reviews Microbiology, 2004, v. 2, n. 12, p. 924, doi. 10.1038/nrmicro1059

By:

Molloy, Sheilagh

Publication type:

Article

Construction of sea anemone cytolysin-based immunotoxins for selective killing of cancer cells.

Published in:

Revista Cubana de Física, 2009, v. 26, n. 1, p. 15

By:

Tejuca, M.;
Pérez-Barzaga, V.;
Pazos, F.;
Álvarez, C.;
Lanio, M. E.

Publication type:

Article

Hurler Phenotype with Vacuolated Lymphocytes and Elevated Lysosomal Hydrolases - Is it Mucolipidosis?

Published in:

2021

By:

Sharawat, Indar;
Kasinathan, Ananthanarayanan;
Das, Gargi;
Bhatia, Prateek;
Sankhyan, Naveen;
Sharawat, Indar K

Publication type:

Letter

Expression map of entry receptors and infectivity factors for pan-coronaviruses in preimplantation and implantation stage human embryos.

Published in:

Journal of Assisted Reproduction & Genetics, 2021, v. 38, n. 7, p. 1709, doi. 10.1007/s10815-021-02192-3

By:

Colaco, S.;
Chhabria, K.;
Singh, D.;
Bhide, A.;
Singh, N.;
Singh, A.;
Husein, A.;
Mishra, A.;
Sharma, R.;
Ashary, N.;
Modi, D.

Publication type:

Article

Autophagy in normal tissues of camel (Camelus dromedarius) with focus on immunoexpression of LC3 and LC3B.

Published in:

Biotechnic & Histochemistry, 2018, v. 93, n. 8, p. 557, doi. 10.1080/10520295.2018.1470728

By:

Osman, Abdel-Hamid K;
Shintani, Michiko

Publication type:

Article

Uptake and localization mechanisms of fluorescent and colored lipid probes. Part 2. QSAR models that predict localization of fluorescent probes used to identify ('specifically stain') various biomembranes and membranous organelles.

Published in:

Biotechnic & Histochemistry, 2015, v. 90, n. 4, p. 241, doi. 10.3109/10520295.2015.1005129

By:

Horobin, Rw;
Stockert, Jc;
Rashid-Doubell, F

Publication type:

Article

Morphologically distinct types of amyloid plaques point the way to a better understanding of Alzheimer’s disease pathogenesis.

Published in:

Biotechnic & Histochemistry, 2010, v. 85, n. 2, p. 133, doi. 10.3109/10520290903389445

By:

D'Andrea, MR;
Nagele, RG

Publication type:

Article

Esterase Specific Fluorescent Probe: Mechanistic Understanding Using QM/MM Calculation and Cell States Discrimination.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 32, p. 1, doi. 10.1002/chem.202300244

By:

Yadav, Rashmi;
Munan, Subrata;
Kardam, Vandana;
Dutta Dubey, Kshatresh;
Samanta, Animesh

Publication type:

Article

Cellular Detection of a Mitochondria Targeted Brominated Vinyl Triphenylamine Optical Probe (TP−Br) by X‐Ray Fluorescence Microscopy.

Published in:

Chemistry - A European Journal, 2022, v. 28, n. 15, p. 1, doi. 10.1002/chem.202104424

By:

Nagarajan, Sounderya;
Poyer, Florent;
Fourmois, Laura;
Naud‐Martin, Delphine;
Medjoubi, Kadda;
Somogyi, Andrea;
Schanne, Gabrielle;
Henry, Lucas;
Delsuc, Nicolas;
Policar, Clotilde;
Bertrand, Helene C.;
Mahuteau‐Betzer, Florence

Publication type:

Article

Fluorescent Benzothiadiazole Derivatives as Fluorescence Imaging Dyes: A Decade of New Generation Probes.

Published in:

Chemistry - A European Journal, 2022, v. 28, n. 4, p. 1, doi. 10.1002/chem.202103262

By:

Neto, Brenno A. D.;
Correa, Jose R.;
Spencer, John

Publication type:

Article

Tuning the Nanoaggregates of Sialylated Biohybrid Photosensitizers for Intracellular Activation of the Photodynamic Response.

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 37, p. 9634, doi. 10.1002/chem.202100681

By:

Almeida‐Marrero, Verónica;
Mascaraque, Marta;
Jesús Vicente‐Arana, María;
Juarranz, Ángeles;
Torres, Tomás;
Escosura, Andrés

Publication type:

Article

STED Imaging the Dynamics of Lysosomes by Dually Fluorogenic Si‐Rhodamine.

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 37, p. 9620, doi. 10.1002/chem.202100623

By:

Fan, Mengting;
An, Haiyan;
Wang, Chuanfeng;
Huo, Shuhui;
Wang, Ting;
Cui, Xiaoyan;
Zhang, Dazhi

Publication type:

Article

Synthesis and Evaluation of Europium Complexes that Switch on Luminescence in Lysosomes of Living Cells.

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 2, p. 766, doi. 10.1002/chem.202003992

By:

Starck, Matthieu;
Fradgley, Jack D.;
Pal, Robert;
Zwier, Jurriaan M.;
Lamarque, Laurent;
Parker, David

Publication type:

Article

Esterase‐Activatable Synthetic M+/Cl− Channel Induces Apoptosis and Disrupts Autophagy in Cancer Cells.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 52, p. 11946, doi. 10.1002/chem.202002964

By:

Malla, Javid Ahmad;
Sharma, Virender Kumar;
Lahiri, Mayurika;
Talukdar, Pinaki

Publication type:

Article

Cover Feature: Salinomycin Derivatives Kill Breast Cancer Stem Cells by Lysosomal Iron Targeting (Chem. Eur. J. 33/2020).

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 33, p. 7334, doi. 10.1002/chem.202001988

By:

Versini, Antoine;
Colombeau, Ludovic;
Hienzsch, Antje;
Gaillet, Christine;
Retailleau, Pascal;
Debieu, Sylvain;
Müller, Sebastian;
Cañeque, Tatiana;
Rodriguez, Raphaël

Publication type:

Article

Salinomycin Derivatives Kill Breast Cancer Stem Cells by Lysosomal Iron Targeting.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 33, p. 7416, doi. 10.1002/chem.202000335

By:

Versini, Antoine;
Colombeau, Ludovic;
Hienzsch, Antje;
Gaillet, Christine;
Retailleau, Pascal;
Debieu, Sylvain;
Müller, Sebastian;
Cañeque, Tatiana;
Rodriguez, Raphaël

Publication type:

Article

DMT1 Inhibitors Kill Cancer Stem Cells by Blocking Lysosomal Iron Translocation.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 33, p. 7369, doi. 10.1002/chem.202000159

By:

Turcu, Andreea L.;
Versini, Antoine;
Khene, Nadjib;
Gaillet, Christine;
Cañeque, Tatiana;
Müller, Sebastian;
Rodriguez, Raphaël

Publication type:

Article

Assembly of a Highly Stable Luminescent Zn5 Cluster and Application to Bio-Imaging.

Published in:

Angewandte Chemie, 2016, v. 128, n. 38, p. 11579, doi. 10.1002/ange.201604813

By:

Zeng, Ming ‐ Hua;
Yin, Zheng;
Liu, Ze ‐ Hui;
Xu, Hai ‐ Bing;
Feng, Ying ‐ Chun;
Hu, Yue ‐ Qiao;
Chang, Li ‐ Xian;
Zhang, Yue ‐ Xing;
Huang, Jin;
Kurmoo, Mohamedally

Publication type:

Article

A Mitochondria-Targeted Photosensitizer Showing Improved Photodynamic Therapy Effects Under Hypoxia.

Published in:

Angewandte Chemie, 2016, v. 128, n. 34, p. 10101, doi. 10.1002/ange.201604130

By:

Lv, Wen;
Zhang, Zhang;
Zhang, Kenneth Yin;
Yang, Huiran;
Liu, Shujuan;
Xu, Aqiang;
Guo, Song;
Zhao, Qiang;
Huang, Wei

Publication type:

Article

Highly Charged Ruthenium(II) Polypyridyl Complexes as Lysosome-Localized Photosensitizers for Two-Photon Photodynamic Therapy.

Published in:

Angewandte Chemie, 2015, v. 127, n. 47, p. 14255, doi. 10.1002/ange.201507800

By:

Huang, Huaiyi;
Yu, Bole;
Zhang, Pingyu;
Huang, Juanjuan;
Chen, Yu;
Gasser, Gilles;
Ji, Liangnian;
Chao, Hui

Publication type:

Article

A D-Peptide Ligand of Nicotine Acetylcholine Receptors for Brain-Targeted Drug Delivery.

Published in:

Angewandte Chemie, 2015, v. 127, n. 10, p. 3066, doi. 10.1002/ange.201411226

By:

Wei, Xiaoli;
Zhan, Changyou;
Shen, Qing;
Fu, Wei;
Xie, Cao;
Gao, Jie;
Peng, Chunmei;
Zheng, Ping;
Lu, Weiyue

Publication type:

Article

Theranostic Iridium(III) Complexes as One- and Two-Photon Phosphorescent Trackers to Monitor Autophagic Lysosomes.

Published in:

Angewandte Chemie, 2014, v. 126, n. 45, p. 12333, doi. 10.1002/ange.201407468

By:

He, Liang;
Tan, Cai ‐ Ping;
Ye, Rui ‐ Rong;
Zhao, Yi ‐ Zhi;
Liu, Ya ‐ Hong;
Zhao, Qiang;
Ji, Liang ‐ Nian;
Mao, Zong ‐ Wan

Publication type:

Article

Imaging Lipid Metabolism in Live Caenorhabditis elegans Using Fingerprint Vibrations.

Published in:

Angewandte Chemie, 2014, v. 126, n. 44, p. 11981, doi. 10.1002/ange.201406029

By:

Wang, Ping;
Liu, Bin;
Zhang, Delong;
Belew, Micah Y.;
Tissenbaum, Heidi A.;
Cheng, Ji ‐ Xin

Publication type:

Article

Lysosomal pH Rise during Heat Shock Monitored by a Lysosome-Targeting Near-Infrared Ratiometric Fluorescent Probe.

Published in:

Angewandte Chemie, 2014, v. 126, n. 41, p. 11096, doi. 10.1002/ange.201405742

By:

Wan, Qiongqiong;
Chen, Suming;
Shi, Wen;
Li, Lihong;
Ma, Huimin

Publication type:

Article

Single-Particle Tracking and Modulation of Cell Entry Pathways of a Tetrahedral DNA Nanostructure in Live Cells.

Published in:

Angewandte Chemie, 2014, v. 126, n. 30, p. 7879, doi. 10.1002/ange.201403236

By:

Liang, Le;
Li, Jiang;
Li, Qian;
Huang, Qing;
Shi, Jiye;
Yan, Hao;
Fan, Chunhai

Publication type:

Article

NMR Fingerprints of the Drug-like Natural-Product Space Identify Iotrochotazine A: A Chemical Probe to Study Parkinson's Disease.

Published in:

Angewandte Chemie, 2014, v. 126, n. 24, p. 6184, doi. 10.1002/ange.201402239

By:

Grkovic, Tanja;
Pouwer, Rebecca H.;
Vial, Marie-Laure;
Gambini, Luca;
Noël, Alba;
Hooper, John N. A.;
Wood, Stephen A.;
Mellick, George D.;
Quinn, Ronald J.

Publication type:

Article

Organelle-Specific Activity-Based Protein Profiling in Living Cells.

Published in:

Angewandte Chemie, 2014, v. 126, n. 11, p. 2963, doi. 10.1002/ange.201309135

By:

Wiedner, Susan D.;
Anderson, Lindsey N.;
Sadler, Natalie C.;
Chrisler, William B.;
Kodali, Vamsi K.;
Smith, Richard D.;
Wright, Aaron T.

Publication type:

Article

Development of a MALDI-TOF MS Strategy for the High-Throughput Analysis of Biomarkers: On-Target Aptamer Immobilization and Laser-Accelerated Proteolysis.

Published in:

Angewandte Chemie, 2013, v. 125, n. 23, p. 6171, doi. 10.1002/ange.201300566

By:

Zhang, Xueyang;
Zhu, Shaochun;
Xiong, Ya;
Deng, Chunhui;
Zhang, Xiangmin

Publication type:

Article

Zinc(II) ion mediates tamoxifen-induced autophagy and cell death in MCF-7 breast cancer cell line.

Published in:

BioMetals, 2010, v. 23, n. 6, p. 997, doi. 10.1007/s10534-010-9346-9

By:

Hwang, Jung;
Kim, Ha;
Kim, Jean;
Cho, Dong-Hyung;
Kim, Mi;
Kim, Yong-Sook;
Kim, Yunha;
Park, Sung-Jin;
Koh, Jae-Young

Publication type:

Article