Works matching DE "LYSOPHOSPHATIDIC acid receptors"

Results: 43

Melanoma Cells Break Down LPA to Establish Local Gradients That Drive Chemotactic Dispersal.

Published in:

PLoS Biology, 2014, v. 12, n. 10, p. 1, doi. 10.1371/journal.pbio.1001966

By:

Muinonen-Martin, Andrew J.;
Susanto, Olivia;
Zhang, Qifeng;
Smethurst, Elizabeth;
Faller, William J.;
Veltman, Douwe M.;
Kalna, Gabriela;
Lindsay, Colin;
Bennett, Dorothy C.;
Sansom, Owen J.;
Herd, Robert;
Jones, Robert;
Machesky, Laura M.;
Wakelam, Michael J. O.;
Knecht, David A.;
Insall, Robert H.

Publication type:

Article

Antifibrotic effect of lysophosphatidic acid receptors LPA1 and LPA3 antagonist on experimental murine scleroderma induced by bleomycin.

Published in:

Experimental Dermatology, 2015, v. 24, n. 9, p. 698, doi. 10.1111/exd.12752

By:

Ohashi, Takenobu;
Yamamoto, Toshiyuki

Publication type:

Article

The autotaxin-lysophosphatidic acid-lysophosphatidic acid receptor cascade: proposal of a novel potential therapeutic target for treating glioblastoma multiforme.

Published in:

Lipids in Health & Disease, 2015, v. 14, n. 1, p. 1, doi. 10.1186/s12944-015-0059-5

By:

Tabuchi, Sadaharu

Publication type:

Article

LPA receptor 1 mediates LPA-induced ovarian cancer metastasis: an in vitro and in vivo study.

Published in:

BMC Cancer, 2016, v. 16, p. 1, doi. 10.1186/s12885-016-2865-1

By:

Xuechen Yu;
Yuanzhen Zhang;
Huijun Chen

Publication type:

Article

Multi-Target Protective Effects of Gintonin in 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-Mediated Model of Parkinson's Disease via Lysophosphatidic Acid Receptors.

Published in:

Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2018.00515

By:

Jong Hee Choi;
Minhee Jang;
Seikwan Oh;
Seung-Yeol Nah;
Ik-Hyun Cho

Publication type:

Article

Transgenic Expression of Human Lysophosphatidic Acid Receptor LPA2 in Mouse Intestinal Epithelial Cells Induces Intestinal Dysplasia.

Published in:

PLoS ONE, 2016, v. 11, n. 4, p. 1, doi. 10.1371/journal.pone.0154527

By:

Yoshida, Michihiro;
He, Peijian;
Yun, C. Chris

Publication type:

Article

Expression of lysophosphatidic acid receptors and local invasiveness and metastasis in Chinese pancreatic cancers.

Published in:

Current Oncology, 2012, v. 19, n. 4, p. eS15, doi. 10.3747/co.19.1138

By:

Gong, Y. L.;
Tao, C. J.;
Hu, M.;
Chen, J. F.;
Cao, X. F.;
Lv, G. M.;
Li, P.

Publication type:

Article

Loss of lysophosphatidic acid receptor LPA alters oligodendrocyte differentiation and myelination in the mouse cerebral cortex.

Published in:

Brain Structure & Function, 2015, v. 220, n. 6, p. 3701, doi. 10.1007/s00429-014-0885-7

By:

García-Díaz, Beatriz;
Riquelme, Raquel;
Varela-Nieto, Isabel;
Jiménez, Antonio;
Diego, Isabel;
Gómez-Conde, Ana;
Matas-Rico, Elisa;
Aguirre, José;
Chun, Jerold;
Pedraza, Carmen;
Santín, Luis;
Fernández, Oscar;
Rodríguez de Fonseca, Fernando;
Estivill-Torrús, Guillermo

Publication type:

Article

Activation of Lysophosphatidic Acid Receptor Type 1 Contributes to Pathophysiology of Spinal Cord Injury.

Published in:

Journal of Neuroscience, 2015, v. 35, n. 28, p. 10224, doi. 10.1523/JNEUROSCI.4703-14.2015

By:

Santos-Nogueira, Eva;
López-Serrano, Clara;
Hernández, Joaquim;
Lago, Natalia;
Astudillo, Alma M.;
Balsinde, Jesús;
Estivill-Torrús, Guillermo;
Rodriguez de Fonseca, Fernando;
Chun, Jerold;
López-Vales, Rubèn

Publication type:

Article

Lysophosphatidic acid and its receptors LPA1 and LPA3 mediate paclitaxel-induced neuropathic pain in mice.

Published in:

Molecular Pain, 2014, v. 10, n. 1, p. 1, doi. 10.1186/1744-8069-10-71

By:

Hitoshi Uchida;
Jun Nagai;
Hiroshi Ueda

Publication type:

Article

Aberrant expression and potential therapeutic target of lysophosphatidic acid receptor 3 in triple-negative breast cancers.

Published in:

Clinical & Experimental Medicine, 2015, v. 15, n. 3, p. 371, doi. 10.1007/s10238-014-0306-5

By:

Sun, Kai;
Cai, Hui;
Duan, Xiaoyi;
Yang, Ya;
Li, Min;
Qu, Jingkun;
Zhang, Xu;
Wang, Jiansheng

Publication type:

Article

A transgenic mouse model for the in vivo bioluminescence imaging of the expression of the lysophosphatidic acid receptor 3: relevance for inflammation and uterine physiology research.

Published in:

Transgenic Research, 2015, v. 24, n. 4, p. 625, doi. 10.1007/s11248-015-9882-8

By:

Zhao, Chenqi;
Sardella, Anne;
Davis, Lynn;
Poubelle, Patrice;
Bourgoin, Sylvain;
Fernandes, Maria

Publication type:

Article

Effect of Inhibition of the Lysophosphatidic Acid Receptor 1 on Metastasis and Metastatic Dormancy in Breast Cancer.

Published in:

JNCI: Journal of the National Cancer Institute, 2012, v. 104, n. 17, p. 1306, doi. 10.1093/jnci/djs319

By:

Marshall, Jean-Claude A.;
Collins, Joshua W.;
Nakayama, Joji;
Horak, Christine E.;
Liewehr, David J.;
Steinberg, Seth M.;
Albaugh, Mary;
Vidal-Vanaclocha, Fernando;
Palmieri, Diane;
Barbier, Maryse;
Murone, Maximilien;
Steeg, Patricia S.

Publication type:

Article

Differential expression of lysophosphatidic acid (LPA) receptors in human ovarian carcinomas.

Published in:

European Journal of Gynaecological Oncology, 2017, v. 38, n. 4, p. 564, doi. 10.12892/ejgo3427.2017

By:

Xiong, Y.;
Xiong, Y. Y.;
Xu, Z. G.;
Cai, H. B.

Publication type:

Article

G Protein-coupled receptors: Expanding the detection of GPCR activation.

Published in:

2012

By:

Faruqi, Mariam

Publication type:

journal article

Regulation of silicosis formation by lysophosphatidic acid and its receptors.

Published in:

Experimental Lung Research, 2014, v. 40, n. 7, p. 317, doi. 10.3109/01902148.2014.920438

By:

Cong, Cuicui;
Mao, Lijun;
Zhang, Yanlin;
Zhao, Zanmei;
Xu, Xixian;
Zhao, Jinyuan

Publication type:

Article

Alpha conotoxin-BuIA globular isomer is a competitive antagonist for oleoyl-L-alpha-lysophosphatidic acid binding to LPAR6; A molecular dynamics study.

Published in:

PLoS ONE, 2017, v. 12, n. 12, p. 1, doi. 10.1371/journal.pone.0189154

By:

Younis, Saima;
Rashid, Sajid

Publication type:

Article

The Small GTPase Rho: Cellular Functions and Signal Transduction.

Published in:

Journal of Biochemistry, 1996, v. 120, n. 2, p. 215, doi. 10.1093/oxfordjournals.jbchem.a021401

By:

Narumiya, Shuh

Publication type:

Article

Retraction of: p2y5/LPA6 attenuates LPA1-mediated VE-cadherin translocation and cell–cell dissociation through G12/13 protein–Src–Rap1.

Published in:

Cardiovascular Research, 2012, v. 94, n. 1, p. 163, doi. 10.1093/cvr/cvs087

By:

Kimura, Takao;
Mogi, Chihiro;
Sato, Koichi;
Tomura, Hideaki;
Ohta, Hideo;
Im, Doon-Soon;
Kuwabara, Atsushi;
Kurose, Hitoshi;
Murakami, Masami;
Okajima, Fumikazu

Publication type:

Article

AM966, an Antagonist of Lysophosphatidic Acid Receptor 1, Increases Lung Microvascular Endothelial Permeability through Activation of Rho Signaling Pathway and Phosphorylation of VE-Cadherin.

Published in:

Mediators of Inflammation, 2017, p. 1, doi. 10.1155/2017/6893560

By:

Cai, Junting;
Wei, Jianxin;
Li, Shuang;
Suber, Tomeka;
Zhao, Jing

Publication type:

Article

Comparative analyses of lysophosphatidic acid receptor-mediated signaling.

Published in:

Cellular & Molecular Life Sciences, 2015, v. 72, n. 12, p. 2377, doi. 10.1007/s00018-015-1872-8

By:

Fukushima, Nobuyuki;
Ishii, Shoichi;
Tsujiuchi, Toshifumi;
Kagawa, Nao;
Katoh, Kazutaka

Publication type:

Article

Lysophosphatidic acid receptors LPA4 and LPA6 differentially promote lymphocyte transmigration across high endothelial venules in lymph nodes.

Published in:

International Immunology, 2016, v. 28, n. 6, p. 283, doi. 10.1093/intimm/dxv072

By:

Erina Hata;
Naoko Sasaki;
Akira Takeda;
Kazuo Tohya;
Eiji Umemoto;
Noriyuki Akahoshi;
Satoshi Ishii;
Kana Bando;
Takaya Abe;
Kuniyuki Kano;
Junken Aoki;
Haruko Hayasaka;
Masayuki Miyasaka

Publication type:

Article

Role of autotaxin in cancer stem cells.

Published in:

Cancer & Metastasis Reviews, 2018, v. 37, n. 2/3, p. 509, doi. 10.1007/s10555-018-9745-x

By:

Lee, Dongjun;
Suh, Dong-Soo;
Lee, Sue Chin;
Tigyi, Gabor J.;
Kim, Jae Ho

Publication type:

Article

Descriptor-based Fitting of Lysophosphatidic Acid Receptor 3 Antagonists into a Single Predictive Mathematical Model.

Published in:

Biomath, 2014, v. 3, n. 2, p. 1, doi. 10.11145/j.biomath.2014.10.061

By:

Omotuyi, Olaposi Idowu;
Hiroshi Ueda

Publication type:

Article

Genetically engineering Crambe abyssinica—A potentially high‐value oil crop for salt land improvement.

Published in:

Land Degradation & Development, 2018, v. 29, n. 4, p. 1096, doi. 10.1002/ldr.2847

By:

Qi, Weicong;
Tinnenbroek‐capel, Iris E. M.;
Salentijn, Elma M. J.;
Zhang, Zhao;
Huang, Bangquan;
Cheng, Jihua;
Shao, Hongbo;
Visser, Richard G. F.;
Krens, Frans A.;
Van Loo, Eibertus N.

Publication type:

Article

Lys39-Lysophosphatidate Carbonyl Oxygen Interaction Locks LPA1 N-terminal Cap to the Orthosteric Site and partners Arg124 During Receptor Activation.

Published in:

Scientific Reports, 2015, p. 13343, doi. 10.1038/srep13343

By:

Omotuyi, Olaposi I.;
Nagai, Jun;
Ueda, Hiroshi

Publication type:

Article

Self-reinforcing loop of amphiregulin and Y-box binding protein-1 contributes to poor outcomes in ovarian cancer.

Published in:

Oncogene, 2014, v. 33, n. 22, p. 2846, doi. 10.1038/onc.2013.259

By:

Panupinthu, N;
Yu, S;
Zhang, D;
Zhang, F;
Gagea, M;
Lu, Y;
Grandis, J R;
Dunn, S E;
Lee, H Y;
Mills, G B

Publication type:

Article

Gene expression of the lysophosphatidic acid receptor 1 is a target of transforming growth factor beta.

Published in:

Oncogene, 2013, v. 32, n. 26, p. 3198, doi. 10.1038/onc.2012.325

By:

Wu, J;
Mukherjee, A;
Lebman, D A;
Fang, X

Publication type:

Article

Phosphorylation and Internalization of Lysophosphatidic Acid Receptors LPA1, LPA2, and LPA3.

Published in:

PLoS ONE, 2015, v. 10, n. 10, p. 1, doi. 10.1371/journal.pone.0140583

By:

Alcántara-Hernández, Rocío;
Hernández-Méndez, Aurelio;
Campos-Martínez, Gisselle A.;
Meizoso-Huesca, Aldo;
García-Sáinz, J. Adolfo

Publication type:

Article

Identification of Heparin-Binding EGF-Like Growth Factor (HB-EGF) as a Biomarker for Lysophosphatidic Acid Receptor Type 1 (LPA1) Activation in Human Breast and Prostate Cancers.

Published in:

PLoS ONE, 2014, v. 9, n. 5, p. 1, doi. 10.1371/journal.pone.0097771

By:

David, Marion;
Sahay, Debashish;
Mege, Florence;
Descotes, Françoise;
Leblanc, Raphaël;
Ribeiro, Johnny;
Clézardin, Philippe;
Peyruchaud, Olivier

Publication type:

Article

Expression of Lysophosphatidic Acid Receptor 1 and Relation with Cell Proliferation, Apoptosis, and Angiogenesis on Preneoplastic Changes Induced by Cadmium Chloride in the Rat Ventral Prostate.

Published in:

PLoS ONE, 2013, v. 8, n. 2, p. 1, doi. 10.1371/journal.pone.0057742

By:

Arriazu, Riánsares;
Durán, Esther;
Pozuelo, José M.;
Santamaria, Luis

Publication type:

Article

Conquered from the Deep Sea? A New Deep-Sea Isopod Species from the Antarctic Shelf Shows Pattern of Recent Colonization.

Published in:

PLoS ONE, 2012, v. 7, n. 11, p. 1, doi. 10.1371/journal.pone.0049354

By:

Riehl, Torben;
Kaiser, Stefanie

Publication type:

Article

Rho/ROCK acts downstream of lysophosphatidic acid receptor 1 in modulating P2X3 receptor-mediated bone cancer pain in rats.

Published in:

Molecular Pain, 2016, v. 12, p. N.PAG, doi. 10.1177/1744806916644929

By:

Wu, Jing-xiang;
Yuan, Xiao-min;
Wang, Qiong;
Wei, Wang;
Xu, Mei-ying

Publication type:

Article

Rho/ROCK acts downstream of lysophosphatidic acid receptor 1 in modulating P2X3 receptor-mediated bone cancer pain in rats.

Published in:

Molecular Pain, 2016, v. 12, p. 1, doi. 10.1177/1744806916644929

By:

Jing-xiang Wu;
Xiao-min Yuan;
Qiong Wang;
Wang Wei;
Mei-ying Xu

Publication type:

Article

Lysophosphatidic acid-induced itch is mediated by signalling of LPA5 receptor, phospholipase D and TRPA1/TRPV1.

Published in:

Journal of Physiology, 2017, v. 595, n. 8, p. 2681, doi. 10.1113/JP273961

By:

Kittaka, Hiroki;
Uchida, Kunitoshi;
Fukuta, Naomi;
Tominaga, Makoto

Publication type:

Article

Lysophosphatidic Acid Pretreatment Attenuates Myocardial Ischemia/Reperfusion Injury in the Immature Hearts of Rats.

Published in:

Frontiers in Physiology, 2017, v. 8, p. 1, doi. 10.3389/fphys.2017.00153

By:

Haibo Chen;
Si Liu;
Xuewen Liu;
Jinjing Yang;
Fang Wang;
Xiangfeng Cong;
Xi Chen

Publication type:

Article

Lysophosphatidic acid activates β-catenin/T cell factor signaling, which contributes to the suppression of apoptosis in H19-7 cells.

Published in:

Molecular Medicine Reports, 2013, v. 8, n. 6, p. 1729, doi. 10.3892/mmr.2013.1743

By:

YUANJIE SUN;
NAM-HO KIM;
LITING JI;
SEUNG-HYUK KIM;
JONGHO LEE;
HAE JIN RHEE

Publication type:

Article

LPA signaling through LPA receptors regulates cellular functions of endothelial cells treated with anticancer drugs.

Published in:

Molecular & Cellular Biochemistry, 2015, v. 408, n. 1/2, p. 147, doi. 10.1007/s11010-015-2490-3

By:

Hirane, Miku;
Tomimatsu, Ayaka;
Fukushima, Nobuyuki;
Araki, Mutsumi;
Ishii, Shuhei;
Takahashi, Kaede;
Mori, Shiori;
Fukushima, Kaori;
Tsujiuchi, Toshifumi

Publication type:

Article

Lysophosphatidic acid receptor-5 negatively regulates cell motile and invasive activities of human sarcoma cell lines.

Published in:

Molecular & Cellular Biochemistry, 2014, v. 393, n. 1/2, p. 17, doi. 10.1007/s11010-014-2042-2

By:

Dong, Yan;
Hirane, Miku;
Araki, Mutsumi;
Fukushima, Nobuyuki;
Honoki, Kanya;
Tsujiuchi, Toshifumi

Publication type:

Article

A novel homozygous variant in the dsp gene underlies the first case of non-syndromic form of alopecia.

Published in:

Archives of Dermatological Research, 2015, v. 307, n. 9, p. 793, doi. 10.1007/s00403-015-1590-y

By:

Jan, Abid;
Basit, Sulman;
Wakil, Salma;
Ramzan, Khushnooda;
Ahmad, Wasim

Publication type:

Article

Activation of Lysophosphatidic Acid Receptor Is Coupled to Enhancement of Ca2+-Activated Potassium Channel Currents.

Published in:

Korean Journal of Physiology & Pharmacology, 2013, v. 17, n. 3, p. 223, doi. 10.4196/kjpp.2013.17.3.223

By:

Sun-Hye Choi;
Byung-Hwan Lee;
Hyeon-Joong Kim;
Sung-Hee Hwang;
Sang-Mok Lee;
Seung-Yeol Nah

Publication type:

Article

Expression of lysophosphatidic acid receptors in the human lower esophageal sphincter.

Published in:

Experimental & Therapeutic Medicine, 2014, v. 7, n. 2, p. 423, doi. 10.3892/etm.2013.1439

By:

YONG FENG;
JUN-FENG LIU

Publication type:

Article

Serotonergic neuron regulation informed by in vivo single-cell transcriptomics.

Published in:

FASEB Journal, 2014, v. 28, n. 2, p. 771, doi. 10.1096/fj.13-240267

By:

Spaethling, Jennifer M.;
Plel, David;
Dueck, Hannah;
Buckley, Peter T.;
Morris, Jacqueline F.;
Fisher, Stephen A.;
JaeHee Lee;
Jai-Yoon Sul;
Junhyong Kim;
Bartfai, Tamas;
Beck, Sheryl G.;
Eberwine, James H.

Publication type:

Article