Works matching DE "LYSINE specific demethylase 1"
Results: 74
KDM1A genetic alterations, a rare cause of primary bilateral macronodular adrenal hyperplasia, strongly associated with food-dependent Cushing's syndrome: results of its systematic germline screening in 301 index cases and genotype/phenotype correlation.
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- European Journal of Endocrinology, 2025, v. 192, n. 2, p. 119, doi. 10.1093/ejendo/lvaf016
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- Article
Lysine-specific demethylase 1 cooperates with BRAF-histone deacetylase complex 80 to enhance HIV-1 Tat-mediated transactivation.
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- Virus Genes, 2018, v. 54, n. 5, p. 662, doi. 10.1007/s11262-018-1589-5
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- Article
Discovery of orally active chalcones as histone lysine specific demethylase 1 inhibitors for the treatment of leukaemia.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 207, doi. 10.1080/14756366.2020.1852556
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- Article
LSD1 Activates PI3K/AKT Signaling Through Regulating p85 Expression in Prostate Cancer Cells.
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- Frontiers in Oncology, 2019, p. 1, doi. 10.3389/fonc.2019.00721
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- Article
Porphyromonas gingivalis gingipain is involved in the detachment and aggregation of Aggregatibacter actinomycetemcomitans biofilm.
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- Molecular Oral Microbiology, 2014, v. 29, n. 3, p. 131, doi. 10.1111/omi.12051
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- Article
Mizl Controls Schwann Cell Proliferation via H3K36<sup>me2</sup> Demethylase Kdm8 to Prevent Peripheral Nerve Demyelination.
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- Journal of Neuroscience, 2018, v. 38, n. 4, p. 858, doi. 10.1523/JNEUROSCI.0843-17.2017
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- Article
Impact of Epigenetic Regulation on Head and Neck Squamous Cell Carcinoma.
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- 2019
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- Publication type:
- journal article
Mutations in MurE, the essential UDP- N-acetylmuramoylalanyl- d-glutamate 2,6-diaminopimelate ligase of Corynebacterium glutamicum: effect on l-lysine formation and analysis of systemic consequences.
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- Biotechnology Letters, 2017, v. 39, n. 2, p. 283, doi. 10.1007/s10529-016-2243-8
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- Article
1<sup>st</sup> Symposium on Y-Chromosome Human Proteome Project.
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- Cell Journal (Yakhteh), 2015, v. 16, n. 4, p. 564
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- Article
JMJD3 and vascular injury: the Emperor's new clothes.
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- Cardiovascular Research, 2018, v. 114, n. 14, p. 1825, doi. 10.1093/cvr/cvy249
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- Article
Critical role of histone demethylase Jumonji domain-containing protein 3 in the regulation of neointima formation following vascular injury.
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- Cardiovascular Research, 2018, v. 114, n. 14, p. 1894, doi. 10.1093/cvr/cvy176
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- Article
Cancer: Targeting LSD1 in small cell lung cancer.
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- Nature Reviews Drug Discovery, 2015, v. 14, n. 9, p. 602, doi. 10.1038/nrd4722
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- Article
KDM2 Family Members are Regulated by HIF-1 in Hypoxia.
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- Cells (2073-4409), 2017, v. 6, n. 1, p. 8, doi. 10.3390/cells6010008
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- Article
LSD1n is an H4K20 demethylase regulating memory formation via transcriptional elongation control.
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- Nature Neuroscience, 2015, v. 18, n. 9, p. 1256, doi. 10.1038/nn.4069
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- Article
Histone demethylase Lsd1 is required for the differentiation of neural cells in Nematostella vectensis.
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- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-28107-z
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- Article
LSD1 (KDM1A)‐independent effects of the LSD1 inhibitor SP2509 in cancer cells.
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- British Journal of Haematology, 2018, v. 183, n. 3, p. 494, doi. 10.1111/bjh.14983
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- Article
ORY‐1001, a KDM1A inhibitor, inhibits proliferation, and promotes apoptosis of triple negative breast cancer cells by inactivating androgen receptor.
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- Drug Development Research, 2022, v. 83, n. 1, p. 208, doi. 10.1002/ddr.21860
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- Publication type:
- Article
Loss of LSD1 (lysine-specific demethylase 1) suppresses growth and alters gene expression of human colon cancer cells in a p53- and DNMT1 (DNA methyltransferase 1)-independent manner.
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- Biochemical Journal, 2013, v. 449, n. 2, p. 459, doi. 10.1042/BJ20121360
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- Article
GFI1B and LSD1 repress myeloid traits during megakaryocyte differentiation.
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- Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-06090-z
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- Article
Sensory systems: Making a choice and sticking with it.
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- Nature Reviews Neuroscience, 2013, v. 14, n. 9, p. 590, doi. 10.1038/nrn3572
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- Publication type:
- Article
Lysine specific demethylase 1 inhibits sodium arsenite activation of HSCs by regulating SESN2/AMPK/ULK1 signaling pathway activity.
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- Environmental Toxicology, 2024, v. 39, n. 6, p. 3563, doi. 10.1002/tox.24184
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- Article
LSD1 inhibition modulates transcription factor networks in myeloid malignancies.
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- Frontiers in Oncology, 2023, v. 13, p. 1, doi. 10.3389/fonc.2023.1149754
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- Publication type:
- Article
Lysine specific demethylase 1 is a molecular driver and therapeutic target in sarcoma.
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- Frontiers in Oncology, 2023, v. 12, p. 1, doi. 10.3389/fonc.2022.1076581
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- Publication type:
- Article
Lysine-specific demethylase 1 restricts hematopoietic progenitor proliferation and is essential for terminal differentiation.
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- Leukemia (08876924), 2012, v. 26, n. 9, p. 2039, doi. 10.1038/leu.2012.157
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- Article
Pharmacological inhibition of LSD1 for the treatment of MLL-rearranged leukemia.
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- Journal of Hematology & Oncology, 2016, v. 9, p. 1, doi. 10.1186/s13045-016-0252-7
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- Article
CoREST1 Promotes Tumor Formation and Tumor Stroma Interactions in a Mouse Model of Breast Cancer.
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- PLoS ONE, 2015, v. 10, n. 3, p. 1, doi. 10.1371/journal.pone.0121281
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- Article
AACR Meeting Highlights New Findings on Drug Resistance, Targeted Therapies.
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- Cancer (0008543X), 2013, v. 119, n. 18, p. 3259, doi. 10.1002/cncr.28337
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- Article
The Combined Effect of Retinoic Acid and LSD1 siRNA Inhibition on Cell Death in the Human Neuroblastoma Cell Line SH-SY5Y.
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- Cellular Physiology & Biochemistry (Karger AG), 2013, v. 31, n. 6, p. 854, doi. 10.1159/000350103
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- Article
中低强度运动干预高脂饲养小鼠膝关节损伤软骨细胞 LncRNA HOTAIR 的表达.
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- Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu, 2024, v. 28, n. 11, p. 1684, doi. 10.12307/2024.221
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- Article
Lysine-Specific Demethylase 1A as a Promising Target in Acute Myeloid Leukemia.
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- Frontiers in Oncology, 2018, p. 1, doi. 10.3389/fonc.2018.00255
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- Publication type:
- Article
Novel compounds protect auditory hair cells against gentamycin-induced apoptosis by maintaining the expression level of H3K4me2.
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- Drug Delivery, 2018, v. 25, n. 1, p. 1033, doi. 10.1080/10717544.2018.1461277
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- Publication type:
- Article
Nuclear import of human histone lysine-specific demethylase LSD1.
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- Journal of Biochemistry, 2014, v. 156, n. 6, p. 305, doi. 10.1093/jb/mvu042
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- Publication type:
- Article
Identification of Novel Selective Lysine-Specific Demethylase 1 ( LSD1) Inhibitors Using a Pharmacophore-Based Virtual Screening Combined with Docking.
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- 2015
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- Publication type:
- Editorial
Regulation of tissue factor pathway inhibitor-2 (TFPI-2) expression by lysine-specific demethylase 1 and 2 (LSD1 and LSD2).
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- Bioscience, Biotechnology & Biochemistry, 2014, v. 78, n. 6, p. 1010, doi. 10.1080/09168451.2014.910104
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- Publication type:
- Article
CBB1003, a lysine-specific demethylase 1 inhibitor, suppresses colorectal cancer cells growth through down-regulation of leucine-rich repeat-containing G-protein-coupled receptor 5 expression.
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- Journal of Cancer Research & Clinical Oncology, 2015, v. 141, n. 1, p. 11, doi. 10.1007/s00432-014-1782-4
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- Article
Targeting Nuclear LSD1 to Reprogram Cancer Cells and Reinvigorate Exhausted T Cells via a Novel LSD1-EOMES Switch.
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- Frontiers in Immunology, 2020, v. 11, p. 1, doi. 10.3389/fimmu.2020.01228
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- Publication type:
- Article
SP1-induced upregulation of lncRNA SPRY4-IT1 exerts oncogenic properties by scaffolding EZH2/LSD1/DNMT1 and sponging miR-101-3p in cholangiocarcinoma.
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- Journal of Experimental & Clinical Cancer Research (17569966), 2018, v. 37, n. 1, p. N.PAG, doi. 10.1186/s13046-018-0747-x
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- Article
KDM1A/LSD1 regulates the differentiation and maintenance of spermatogonia in mice.
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- PLoS ONE, 2017, v. 12, n. 5, p. 1, doi. 10.1371/journal.pone.0177473
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- Publication type:
- Article
Structure activity relationship and modeling studies of inhibitors of lysine specific demethylase 1.
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- PLoS ONE, 2017, v. 12, n. 2, p. 1, doi. 10.1371/journal.pone.0170301
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- Publication type:
- Article
Evolution Increases Primates Brain Complexity Extending RbFOX1 Splicing Activity to LSD1 Modulation.
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- Journal of Neuroscience, 2022, v. 42, n. 18, p. 3689, doi. 10.1523/JNEUROSCI.1782-21.2022
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- Publication type:
- Article
PHF21A Related Disorder: Description of a New Case.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 24, p. 16130, doi. 10.3390/ijms232416130
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- Publication type:
- Article
Endocannabinoid-Epigenetic Cross-Talk: A Bridge toward Stress Coping.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 17, p. 6252, doi. 10.3390/ijms21176252
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- Publication type:
- Article
Machine-Learning-Enabled Virtual Screening for Inhibitors of Lysine-Specific Histone Demethylase 1.
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- Molecules, 2021, v. 26, n. 24, p. 7492, doi. 10.3390/molecules26247492
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- Article
Investigating the Binding Mode of Reversible LSD1 Inhibitors Derived from Stilbene Derivatives by 3D-QSAR, Molecular Docking, and Molecular Dynamics Simulation.
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- Molecules, 2019, v. 24, n. 24, p. 4479, doi. 10.3390/molecules24244479
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- Article
Design, Synthesis and Biological Evaluation of Novel Osimertinib-Based HDAC and EGFR Dual Inhibitors.
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- Molecules, 2019, v. 24, n. 13, p. 2407, doi. 10.3390/molecules24132407
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- Publication type:
- Article
Crosstalk between lysine-specific demethylase 1 (LSD1) and histone deacetylases mediates antineoplastic efficacy of HDAC inhibitors in human breast cancer cells.
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- Carcinogenesis, 2013, v. 34, n. 6, p. 1196, doi. 10.1093/carcin/bgt033
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- Publication type:
- Article
Phase I trials of the lysine-specific demethylase 1 inhibitor, GSK2879552, as mono- and combination-therapy in relapsed/refractory acute myeloid leukemia or high-risk myelodysplastic syndromes.
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- 2022
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- Publication type:
- Letter
Efficacy of Vafidemstat in Experimental Autoimmune Encephalomyelitis Highlights the KDM1A/RCOR1/HDAC Epigenetic Axis in Multiple Sclerosis.
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- Pharmaceutics, 2022, v. 14, n. 7, p. N.PAG, doi. 10.3390/pharmaceutics14071420
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- Publication type:
- Article
Novel dual LSD1/HDAC6 inhibitor for the treatment of cancer.
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- PLoS ONE, 2023, v. 18, n. 1, p. 1, doi. 10.1371/journal.pone.0279063
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- Publication type:
- Article
Retinoic Acid Induces Ubiquitination-Resistant RIP140/LSD1 Complex to Fine-Tune P ax6 Gene in Neuronal Differentiation.
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- Stem Cells, 2016, v. 34, n. 1, p. 114, doi. 10.1002/stem.2190
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- Publication type:
- Article