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In vitro, in vivo metabolism and quantification of the novel synthetic opioid N-piperidinyl etonitazene (etonitazepipne).
- Published in:
- Clinical Chemistry & Laboratory Medicine, 2024, v. 62, n. 8, p. 1580, doi. 10.1515/cclm-2023-1360
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- Article
Physiologically based pharmacokinetic modeling for confirming the role of CYP3A1/2 and P‐glycoprotein in detoxification mechanism between glycyrrhizic acid and aconitine in rats.
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- Journal of Applied Toxicology, 2024, v. 44, n. 7, p. 978, doi. 10.1002/jat.4595
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- Article
The First In Vivo Study Shows That Gyrophoric Acid Changes Behavior of Healthy Laboratory Rats.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 12, p. 6782, doi. 10.3390/ijms25126782
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- Article
The influence of drug-induced metabolic enzyme activity inhibition and CYP3A4 gene polymorphism on aumolertinib metabolism.
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- Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1392849
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- Article
Anthraquinone biocolourant dermocybin is metabolized whereas dermorubin is not in in vitro liver fractions and recombinant metabolic enzymes.
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- Basic & Clinical Pharmacology & Toxicology, 2024, v. 134, n. 6, p. 846, doi. 10.1111/bcpt.14013
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- Article
Characterization of iso-LSD metabolism using human liver microsomes in comparison to LSD and its applicability as urinary biomarker for LSD consumption.
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- Journal of Analytical Toxicology, 2024, v. 48, n. 5, p. 281, doi. 10.1093/jat/bkae023
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- Article
Comparison of reversed-phase, hydrophilic interaction, and porous graphitic carbon chromatography columns for an untargeted toxicometabolomics study in pooled human liver microsomes, rat urine, and rat plasma.
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- Metabolomics, 2024, v. 20, n. 3, p. 1, doi. 10.1007/s11306-024-02115-0
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- Article
Metabolism, Disposition, Excretion, and Potential Transporter Inhibition of 7–16, an Improving 5-HT 2A Receptor Antagonist and Inverse Agonist for Parkinson's Disease.
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- Molecules, 2024, v. 29, n. 10, p. 2184, doi. 10.3390/molecules29102184
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- Article
Metabolism of ADB‐FUBIATA in zebrafish and pooled human liver microsomes investigated by liquid chromatography–high‐resolution mass spectrometry.
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- Rapid Communications in Mass Spectrometry: RCM, 2024, v. 38, n. 9, p. 1, doi. 10.1002/rcm.9730
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- Article
In vitro and in vivo metabolism of psilocybin's active metabolite psilocin.
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- Frontiers in Pharmacology, 2024, p. 01, doi. 10.3389/fphar.2024.1391689
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- Article
The impacts of natural product miltirone and the CYP2D6 pharmacogenetic phenotype on fluoxetine metabolism.
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- Frontiers in Pharmacology, 2024, p. 01, doi. 10.3389/fphar.2024.1373048
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- Article
In vitro and in vivo metabolic study of three new psychoactive β-keto-arylcyclohexylamines.
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- Journal of Analytical Toxicology, 2024, v. 48, n. 4, p. 217, doi. 10.1093/jat/bkae020
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- Article
In Vivo and In Vitro Metabolic Fate and Urinary Detectability of Five Deschloroketamine Derivatives Studied by Means of Hyphenated Mass Spectrometry.
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- Metabolites (2218-1989), 2024, v. 14, n. 5, p. 270, doi. 10.3390/metabo14050270
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- Article
Identification of New Hepatic Metabolites of Miconazole by Biological and Electrochemical Methods Using Ultra-High-Performance Liquid Chromatography Combined with High-Resolution Mass Spectrometry.
- Published in:
- Molecules, 2024, v. 29, n. 9, p. 2160, doi. 10.3390/molecules29092160
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- Article
Online electrochemistry coupling liquid chromatography-mass spectrometry for rapid investigation on the phase I and phase II simulated metabolic reactions of flavonoids.
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- Analytical & Bioanalytical Chemistry, 2024, v. 416, n. 10, p. 2541, doi. 10.1007/s00216-024-05227-7
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- Article
Effect of P. corylifolia on the pharmacokinetic profile of tofacitinib and the underlying mechanism.
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- Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1351882
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- Article
Gender difference in the pharmacokinetics and metabolism of VX‐548 in rats.
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- Biopharmaceutics & Drug Disposition, 2024, v. 45, n. 2, p. 107, doi. 10.1002/bdd.2387
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- Article
On the Possible Effect of Phytic Acid (Myo-Inositol Hexaphosphoric Acid, IP6) on Cytochromes P450 and Systems of Xenobiotic Metabolism in Different Hepatic Models.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 7, p. 3610, doi. 10.3390/ijms25073610
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- Article
Protection of schisantherin A against dictamnine‐induced hepatotoxicity: Pharmacokinetic insights.
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- Journal of Applied Toxicology, 2024, v. 44, n. 4, p. 501, doi. 10.1002/jat.4557
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- Article
Multifaceted Characterization for the Hepatic Clearance of Graphene Oxide and Size-Related Hepatic Toxicity.
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- Molecules, 2024, v. 29, n. 6, p. 1335, doi. 10.3390/molecules29061335
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- Article
Evaluation on the Potential for Hepatotoxic Components from Herba Epimedii to Induce Apoptosis in HepG2 Cells and the Analysis of the Influence of Metabolism in Liver Microsomes.
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- Molecules, 2024, v. 29, n. 6, p. 1354, doi. 10.3390/molecules29061354
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- Article
Hepatic glucuronidation of tetrabromobisphenol A and tetrachlorobisphenol A: interspecies differences in humans and laboratory animals and responsible UDP-glucuronosyltransferase isoforms in humans.
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- Archives of Toxicology, 2024, v. 98, n. 3, p. 837, doi. 10.1007/s00204-023-03659-1
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- Article
In Vitro Studies on the Effects of Water Miscible Organic Co-Solvents on Select Drug Metabolizing Enzyme Activities.
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- Indian Journal of Pharmaceutical Sciences, 2024, v. 86, n. 2, p. 556, doi. 10.36468/pharmaceutical-sciences.1308
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- Article
Cannabinoid-Induced Inhibition of Morphine Glucuronidation and the Potential for In Vivo Drug–Drug Interactions.
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- Pharmaceutics, 2024, v. 16, n. 3, p. 418, doi. 10.3390/pharmaceutics16030418
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- Article
Exploration of Cytochrome P450-Related Interactions between Aflatoxin B1 and Tiamulin in Broiler Chickens.
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- Toxins, 2024, v. 16, n. 3, p. 160, doi. 10.3390/toxins16030160
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- Article
Identification and characterization of the metabolites of sinomenine using liquid chromatography combined with benchtop Orbitrap mass spectrometry and nuclear magnetic resonance spectroscopy.
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- Rapid Communications in Mass Spectrometry: RCM, 2024, v. 38, n. 3, p. 1, doi. 10.1002/rcm.9669
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- Article
Evidence for cytochrome P450 3A4‐mediated metabolic activation of SCO‐267.
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- Biopharmaceutics & Drug Disposition, 2024, v. 45, n. 1, p. 30, doi. 10.1002/bdd.2381
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- Article
Differential effects of dietary polyphenols on oral pharmacokinetics of cyclin-dependent kinase inhibitors in rats: a mechanistic framework for in vitro–in vivo extrapolation.
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- Journal of Pharmacy & Pharmacology, 2024, v. 76, n. 2, p. 93, doi. 10.1093/jpp/rgad115
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- Article
Cannabinoid-Induced Stereoselective Inhibition of R-S-Oxazepam Glucuronidation: Cannabinoid–Oxazepam Drug Interactions.
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- Pharmaceutics, 2024, v. 16, n. 2, p. 243, doi. 10.3390/pharmaceutics16020243
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- Article
Metabolic Stability and Metabolite Identification of N-Ethyl Pentedrone Using Rat, Mouse and Human Liver Microsomes.
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- Pharmaceutics, 2024, v. 16, n. 2, p. 257, doi. 10.3390/pharmaceutics16020257
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- Article
In Vitro Metabolism and In Vivo Pharmacokinetics Profiles of Hydroxy-α-Sanshool.
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- Toxics, 2024, v. 12, n. 2, p. 100, doi. 10.3390/toxics12020100
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- Article
Doping control approach: Identification of equine in vitro metabolites of voxelotor (GBT440), a hemoglobin S polymerization inhibitor.
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- Rapid Communications in Mass Spectrometry: RCM, 2024, v. 38, n. 2, p. 1, doi. 10.1002/rcm.9671
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- Article
Pharmacokinetic study of the interaction between luteolin and magnoflorine in rats.
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- Chemical Biology & Drug Design, 2024, v. 103, n. 1, p. 1, doi. 10.1111/cbdd.14356
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- Article
Glycyrrhizin protects against diosbulbin B‐induced hepatotoxicity by inhibiting the metabolic activation of diosbulbin B.
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- Journal of Biochemical & Molecular Toxicology, 2024, v. 38, n. 1, p. 1, doi. 10.1002/jbt.23549
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- Article
Cannabidiol and cannabidiolic acid: Preliminary in vitro evaluation of metabolism and drug–drug interactions involving canine cytochrome P‐450, UDP‐glucuronosyltransferase, and P‐glycoprotein.
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- Journal of Veterinary Pharmacology & Therapeutics, 2024, v. 47, n. 1, p. 1, doi. 10.1111/jvp.13403
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- Article
The Systematic Assessment of the Membrane-Stabilizing and Antioxidant Activities of Several Kazakhstani Plants in the Asteraceae Family.
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- Plants (2223-7747), 2024, v. 13, n. 1, p. 96, doi. 10.3390/plants13010096
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- Article
Investigation of Drug-Interaction Potential for Arthritis Dietary Supplements: Chondroitin Sulfate, Glucosamine, and Methylsulfonylmethane.
- Published in:
- Molecules, 2023, v. 28, n. 24, p. 8068, doi. 10.3390/molecules28248068
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- Article
Inhibitory effect of napabucasin on arbidol metabolism and its mechanism research.
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- Frontiers in Pharmacology, 2023, p. 1, doi. 10.3389/fphar.2023.1292354
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- Article
In vitro metabolic profiling of new synthetic cannabinoids, ADB-FUBIATA, AFUBIATA, CH-FUBIATA, and CH-PIATA.
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- Archives of Toxicology, 2023, v. 97, n. 12, p. 3085, doi. 10.1007/s00204-023-03605-1
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- Article
Evidence of 11-Hydroxy-hexahydrocannabinol and 11-Nor-9-carboxy-hexahydrocannabinol as Novel Human Metabolites of Δ 9 -Tetrahydrocannabinol.
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- Metabolites (2218-1989), 2023, v. 13, n. 12, p. 1169, doi. 10.3390/metabo13121169
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- Article
The effect of icotinib or apatinib on the pharmacokinetic profile of oxycodone in rats and the underlying mechanism.
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- PeerJ, 2023, p. 1, doi. 10.7717/peerj.16601
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- Article
Mechanistic Static Model based Prediction of Transporter Substrate Drug-Drug Interactions Utilizing Atorvastatin and Rifampicin.
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- Pharmaceutical Research, 2023, v. 40, n. 12, p. 3025, doi. 10.1007/s11095-023-03613-x
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- Article
Exploring Metabolic Pathways of Anamorelin, a Selective Agonist of the Growth Hormone Secretagogue Receptor, via Molecular Networking.
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- Pharmaceutics, 2023, v. 15, n. 12, p. 2700, doi. 10.3390/pharmaceutics15122700
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- Article
Preparation of 18 F-Labeled Tracers Targeting Fibroblast Activation Protein via Sulfur [ 18 F]Fluoride Exchange Reaction.
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- Pharmaceutics, 2023, v. 15, n. 12, p. 2749, doi. 10.3390/pharmaceutics15122749
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- Article
Tumor Regression upon Intratumoral and Subcutaneous Dosing of the STING Agonist ALG-031048 in Mouse Efficacy Models.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 22, p. 16274, doi. 10.3390/ijms242216274
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- Article
Metabolic Transformation of Gentiopicrin, a Liver Protective Active Ingredient, Based on Intestinal Bacteria.
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- Molecules, 2023, v. 28, n. 22, p. 7575, doi. 10.3390/molecules28227575
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- Article
Impact of CYP2C:TG Haplotype on CYP2C19 Substrates Clearance In Vivo, Protein Content, and In Vitro Activity.
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- Clinical Pharmacology & Therapeutics, 2023, v. 114, n. 5, p. 1033, doi. 10.1002/cpt.3012
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- Article
Does ketamine show tolerance?
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- 2023
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- Case Study
Evaluation on the Metabolic Activity of Two Carboxylesterase Isozymes in Mouse Liver Microsomes by a LC–MS/MS Method.
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- Journal of Chromatographic Science, 2023, v. 6, n. 10, p. 980, doi. 10.1093/chromsci/bmac105
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- Article
Effects of acaricides on the activities of monooxygenases in bovine liver microsomes.
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- Journal of Veterinary Pharmacology & Therapeutics, 2023, v. 46, n. 6, p. 375, doi. 10.1111/jvp.13395
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- Publication type:
- Article