Works about LIGAND-gated ion channels

Results: 310

Inhibition of NMDA receptors and other ion channel types by membrane-associated drugs.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1561956

By:

Neureiter, Elizabeth G.;
Erickson-Oberg, M. Quincy;
Nigam, Aparna;
Johnson, Jon W.

Publication type:

Article

Terminal Schwann cells: modulators of the neuromuscular junction and a potential target for nerve reinnervation.

Published in:

Journal of Physiology, 2025, v. 603, n. 9, p. 2475, doi. 10.1113/JP288563

By:

Tsang, Quentin K.;
Gallo, Lucas;
Zhu, Xi Ming;
Leveille, Cameron F.

Publication type:

Article

Chromosome-level genome assembly of the synanthropic fly Chrysomya megacephala: insights into oviposition location.

Published in:

BMC Genomics, 2025, v. 26, n. 1, p. 1, doi. 10.1186/s12864-025-11645-3

By:

Ren, Lipin;
Jocelin, Ngando Fernand;
Yang, Fengqin;
Zhang, Xiangyan;
Shang, Yanjie;
Feng, Yakai;
Chen, Shan;
Zhan, Wei;
Yang, Xiaohong;
Li, Wei;
Song, Jiasheng;
Tang, Haojie;
Wang, Yequan;
Wang, Yong;
Zhang, Changquan;
Guo, Yadong

Publication type:

Article

Signal Transduction at the Domain Interface of Prokaryotic Pentameric Ligand-Gated Ion Channels.

Published in:

PLoS Biology, 2016, v. 14, n. 3, p. 1, doi. 10.1371/journal.pbio.1002393

By:

Bertozzi, Carlo;
Zimmermann, Iwan;
Engeler, Sibylle;
Hilf, Ricarda J. C.;
Dutzler, Raimund

Publication type:

Article

External amino acid residues of insect GABA receptor channels dictate the action of the isoxazoline ectoparasiticide fluralaner.

Published in:

Pest Management Science, 2023, v. 79, n. 10, p. 4078, doi. 10.1002/ps.7606

By:

Asahi, Miho;
Yamato, Kohei;
Ozoe, Fumiyo;
Ozoe, Yoshihisa

Publication type:

Article

Success, despite another plague year.

Published in:: Pest Management Science, 2022, v. 78, n. 1, p. 7, doi. 10.1002/ps.6708
Publication type:: Article

Understanding the biological action of insecticides is the key to their continuous improvement.

Published in:

Pest Management Science, 2021, v. 77, n. 8, p. 3605, doi. 10.1002/ps.6488

By:

David, Michael;
Leibowitz, Sarah;
Lorsbach, Beth;
Wing, Keith

Publication type:

Article

The cys‐loop ligand‐gated ion channel gene superfamilies of the cockroaches Blattella germanica and Periplaneta americana.

Published in:

Pest Management Science, 2021, v. 77, n. 8, p. 3787, doi. 10.1002/ps.6245

By:

Jones, Andrew K;
Goven, Delphine;
Froger, Josy‐Anne;
Bantz, Alexandre;
Raymond, Valerie

Publication type:

Article

Change the channel: CysLoop receptor antagonists from nature.

Published in:

Pest Management Science, 2021, v. 77, n. 8, p. 3650, doi. 10.1002/ps.6166

By:

Tong, Guanghu;
Baker, Meghan A;
Shenvi, Ryan A

Publication type:

Article

Important amino acids for function of the insect Rdl GABA receptor.

Published in:

Pest Management Science, 2021, v. 77, n. 8, p. 3753, doi. 10.1002/ps.6121

By:

Nakao, Toshifumi;
Banba, Shinichi

Publication type:

Article

Untangling a Gordian knot: the role of a GluCl3 I321T mutation in abamectin resistance in Tetranychus urticae.

Published in:

Pest Management Science, 2021, v. 77, n. 4, p. 1581, doi. 10.1002/ps.6215

By:

Wenxin Xue;
Mermans, Catherine;
Papapostolou, Kyriaki-Maria;
Lamprousi, Mantha;
Christou, Iason-Konstantinos;
Inak, Emre;
Douris, Vassilis;
Vontas, John;
Dermauw, Wannes;
Van Leeuwen, Thomas

Publication type:

Article

NMDARs activation regulates endothelial ferroptosis via the PP2A-AMPK-HMGB1 axis.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-023-01794-3

By:

Han, Wei-Min;
Hong, Yi-Xiang;
Xiao, Guo-Sheng;
Wang, Rui-Ying;
Li, Gang

Publication type:

Article

Enhancing effect of nicotine on electrical field stimulation elicited contractile responses in isolated rabbit bladder straight muscle; the role of cannabinoid and vanilloid receptors.

Published in:

Turkish Journal of Medical Sciences, 2022, v. 52, n. 6, p. 1814, doi. 10.55730/1300-0144.5527

By:

İLHAN, Sevil Özger;
Öztürk FİNCAN, Gökçe Sevim;
OKÇAY, Yağmur;
KOÇ, Derya Sebile;
AŞKIN, Celil İlker;
KİBAR, Ayşe Kübra;
VURAL, İsmail Mert;
SARIOĞLU, Yusuf

Publication type:

Article

TPC1-Type Channels in Physcomitrium patens : Interaction between EF-Hands and Ca 2+.

Published in:

Plants (2223-7747), 2022, v. 11, n. 24, p. 3527, doi. 10.3390/plants11243527

By:

Mérida-Quesada, Franko;
Vergara-Valladares, Fernando;
Rubio-Meléndez, María Eugenia;
Hernández-Rojas, Naomí;
González-González, Angélica;
Michard, Erwan;
Navarro-Retamal, Carlos;
Dreyer, Ingo

Publication type:

Article

Spotlights on our sister journals: Asian J. Org. Chem. 7/2016.

Published in:: Asian Journal of Organic Chemistry, 2016, v. 5, n. 7, p. 835, doi. 10.1002/ajoc.201680713
Publication type:: Article

Discovery of lipid binding sites in a ligand-gated ion channel by integrating simulations and cryo-EM.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.86016

By:

Bergh, Cathrine;
Rovšnik, Urška;
Howard, Rebecca;
Lindahl, Erik

Publication type:

Article

Targeting NMDA receptor in Alzheimer's disease: identifying novel inhibitors using computational approaches.

Published in:

Frontiers in Pharmacology, 2023, p. 1, doi. 10.3389/fphar.2023.1208968

By:

Siddiqui, Arif Jamal;
Badraoui, Riadh;
Jahan, Sadaf;
Alshahrani, Mohammed Merae;
Siddiqui, Maqsood Ahmed;
Khan, Andleeb;
Adnan, Mohd

Publication type:

Article

Editorial: Purinergic pharmacology, Volume II.

Published in:

Frontiers in Pharmacology, 2023, p. 1, doi. 10.3389/fphar.2023.1200187

By:

Ciruela, Francisco;
Jacobson, Kenneth A.

Publication type:

Article

Cellular and Molecular Targets of Menthol Actions.

Published in:

Frontiers in Pharmacology, 2017, p. 1, doi. 10.3389/fphar.2017.00472

By:

Oz, Murat;
El Nebrisi, Eslam G.;
Yang, Keun-Hang S.;
Howarth, Frank C.;
Al Kury, Lina T.

Publication type:

Article

Cryo-EM structures of prokaryotic ligand-gated ion channel GLIC provide insights into gating in a lipid environment.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-47370-w

By:

Bharambe, Nikhil;
Li, Zhuowen;
Seiferth, David;
Balakrishna, Asha Manikkoth;
Biggin, Philip C.;
Basak, Sandip

Publication type:

Article

A release of local subunit conformational heterogeneity underlies gating in a muscle nicotinic acetylcholine receptor.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-46028-x

By:

Thompson, Mackenzie J.;
Mansoub Bekarkhanechi, Farid;
Ananchenko, Anna;
Nury, Hugues;
Baenziger, John E.

Publication type:

Article

Structural interplay of anesthetics and paralytics on muscle nicotinic receptors.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-38827-5

By:

Goswami, Umang;
Rahman, Md Mahfuzur;
Teng, Jinfeng;
Hibbs, Ryan E.

Publication type:

Article

Evaluation of Developmental and Reproductive Fitness of Laboratory Selected Thiamethoxam Resistance in Black Legume Aphid Aphis craccivora Koch.

Published in:

International Journal of Bio-Resource & Stress Management, 2021, v. 12, n. 3, p. 151, doi. 10.23910/1.2021.2199a

By:

Routray, S.;
Mishra, H. P.

Publication type:

Article

Electromagnetic radiation modulates synchronization in cortical neurons of Macaque brain.

Published in:

International Journal of Modern Physics C: Computational Physics & Physical Computation, 2019, v. 30, n. 8, p. N.PAG, doi. 10.1142/S0129183119500475

By:

Vinaya, Mary;
Ignatius, Rose P.

Publication type:

Article

Acute inhibition of acid sensing ion channel 1a after spinal cord injury selectively affects excitatory synaptic transmission, but not intrinsic membrane properties, in deep dorsal horn interneurons.

Published in:

PLoS ONE, 2023, v. 18, n. 11, p. 1, doi. 10.1371/journal.pone.0289053

By:

Foster, Victoria S.;
Saez, Natalie;
King, Glenn F.;
Rank, Michelle M.

Publication type:

Article

遗传性癫癎与药物精准治疗的研究进展.

Published in:

Chinese Journal of Contemporary Pediatrics, 2017, v. 19, n. 10, p. 1118, doi. 10.7499/j.issn.1008-8830.2017.10.017

By:

吕格;
综述;
韩蕴丽;
审校

Publication type:

Article

Editorial: Targeting ion channels for drug discovery: emerging challenges for high throughput screening technologies.

Published in:

Frontiers in Molecular Neuroscience, 2024, p. 01, doi. 10.3389/fnmol.2024.1414816

By:

Hernandez, Ciria C.;
Gimenez, Luis E.;
Strassmaier, Tim;
Rogers, Marc;
Taymans, Jean-Marc

Publication type:

Article

Delving into the significance of the His289Tyr single-nucleotide polymorphism in the glutamate ionotropic receptor kainate-1 (Grikl) gene of a genetically audiogenic seizure model.

Published in:

Frontiers in Molecular Neuroscience, 2024, p. 01, doi. 10.3389/fnmol.2023.1322750

By:

Díaz-Rodríguez, Sandra M.;
Herrero-Turrión, M. Javier;
García-Peral, Carlos;
Gómez-Nieto, Ricardo

Publication type:

Article

Unsaturated Analogues of the Neurotransmitter GABA: trans-4-Aminocrotonic, cis-4-Aminocrotonic and 4-Aminotetrolic Acids.

Published in:

Neurochemical Research, 2016, v. 41, n. 3, p. 476, doi. 10.1007/s11064-015-1619-9

By:

Johnston, Graham

Publication type:

Article

Non-competitive Inhibition of Nicotinic Acetylcholine Receptors by Ladybird Beetle Alkaloids.

Published in:

Neurochemical Research, 2015, v. 40, n. 10, p. 2078, doi. 10.1007/s11064-014-1466-0

By:

Leong, Ron;
Xing, Hong;
Braekman, Jean-Claude;
Kem, William

Publication type:

Article

Analysis of γ-Aminobutyric Acid (GABA) Type A Receptor Subtypes Using Isosteric and Allosteric Ligands.

Published in:

Neurochemical Research, 2014, v. 39, n. 10, p. 1924, doi. 10.1007/s11064-014-1382-3

By:

Olsen, Richard

Publication type:

Article

The neural γ2α1β2α1β2 gamma amino butyric acid ion channel receptor: structural analysis of the effects of the ivermectin molecule and disulfide bridges.

Published in:

Journal of Molecular Modeling, 2018, v. 24, n. 8, p. 1, doi. 10.1007/s00894-018-3739-z

By:

Ayan, Meral;
Essiz, Sebnem

Publication type:

Article

Brivaracetam does not modulate ionotropic channels activated by glutamate, γ-aminobutyric acid, and glycine in hippocampal neurons.

Published in:

Epilepsia (Series 4), 2017, v. 58, n. 11, p. e157, doi. 10.1111/epi.13890

By:

Niespodziany, Isabelle;
Rigo, Jean ‐ Michel;
Moonen, Gustave;
Matagne, Alain;
Klitgaard, Henrik;
Wolff, Christian

Publication type:

Article

Correction: Transcriptome of the synganglion in the tick Ixodes ricinus and evolution of the cys-loop ligand-gated ion channel family in ticks.

Published in:

2022

By:

Rispe, Claude;
Hervet, Caroline;
de la Cotte, Nathalie;
Daveu, Romain;
Labadie, Karine;
Noel, Benjamin;
Aury, Jean-Marc;
Thany, Steeve;
Taillebois, Emiliane;
Cartereau, Alison;
Le Mauf, Anaïs;
Charvet, Claude L.;
Auger, Clément;
Courtot, Elise;
Neveu, Cédric;
Plantard, Olivier

Publication type:

Correction Notice

Transcriptome of the synganglion in the tick Ixodes ricinus and evolution of the cys-loop ligand-gated ion channel family in ticks.

Published in:

BMC Genomics, 2022, v. 23, n. 1, p. 1, doi. 10.1186/s12864-022-08669-4

By:

Rispe, Claude;
Hervet, Caroline;
de la Cotte, Nathalie;
Daveu, Romain;
Labadie, Karine;
Noel, Benjamin;
Aury, Jean-Marc;
Thany, Steeve;
Taillebois, Emiliane;
Cartereau, Alison;
Le Mauff, Anaïs;
Charvet, Claude L.;
Auger, Clément;
Courtot, Elise;
Neveu, Cédric;
Plantard, Olivier

Publication type:

Article

Un-gating and allosteric modulation of a pentameric ligand-gated ion channel captured by molecular dynamics.

Published in:

PLoS Computational Biology, 2017, v. 13, n. 10, p. 1, doi. 10.1371/journal.pcbi.1005784

By:

Martin, Nicolas E;
Malik, Siddharth;
Calimet, Nicolas;
Changeux, Jean-Pierre;
Cecchini, Marco

Publication type:

Article

Deciphering the regulation of P2X4 receptor channel gating by ivermectin using Markov models.

Published in:

PLoS Computational Biology, 2017, v. 13, n. 7, p. 1, doi. 10.1371/journal.pcbi.1005643

By:

Mackay, Laurent;
Zemkova, Hana;
Stojilkovic, Stanko S.;
Sherman, Arthur;
Khadra, Anmar

Publication type:

Article

Ligand-gated ion channels as targets of neuroactive insecticides.

Published in:

Bioscience, Biotechnology & Biochemistry, 2022, v. 86, n. 2, p. 157, doi. 10.1093/bbb/zbab202

By:

Makoto Ihara

Publication type:

Article

Transient receptor potential vanilloid 1 (TRPV1)‐independent actions of capsaicin on cellular excitability and ion transport.

Published in:

Medicinal Research Reviews, 2023, v. 43, n. 4, p. 1038, doi. 10.1002/med.21945

By:

Oz, Murat;
Lorke, Dietrich E.;
Howarth, Frank C.

Publication type:

Article

Recent advances with 5‐HT3 modulators for neuropsychiatric and gastrointestinal disorders.

Published in:

Medicinal Research Reviews, 2020, v. 40, n. 5, p. 1593, doi. 10.1002/med.21666

By:

Juza, Radomir;
Vlcek, Premysl;
Mezeiova, Eva;
Musilek, Kamil;
Soukup, Ondrej;
Korabecny, Jan

Publication type:

Article

Pharmacophore Mapping Combined with dbCICA Reveal New Structural Features for the Development of Novel Ligands Targeting α4β2 and α7 Nicotinic Acetylcholine Receptors.

Published in:

Molecules, 2022, v. 27, n. 23, p. 8236, doi. 10.3390/molecules27238236

By:

Batista, Victor S.;
Gonçalves, Adriano Marques;
Nascimento-Júnior, Nailton M.

Publication type:

Article

From cis -Lobeline to trans -Lobeline: Study on the Pharmacodynamics and Isomerization Factors.

Published in:

Molecules, 2022, v. 27, n. 19, p. 6253, doi. 10.3390/molecules27196253

By:

Xu, Huan-Hua;
Yang, Liang;
Tang, Ming-Xia;
Ye, An-Ping;
Tu, Bo-Dan;
Jiang, Zhen-Hong;
Yi, Jian-Feng

Publication type:

Article

Synthetic Methods for the Preparation of Conformationally Restricted Analogues of Nicotine.

Published in:

Molecules, 2021, v. 26, n. 24, p. 7544, doi. 10.3390/molecules26247544

By:

Panda, Biswajit;
Albano, Gianluigi

Publication type:

Article

Pursuing High-Resolution Structures of Nicotinic Acetylcholine Receptors: Lessons Learned from Five Decades.

Published in:

Molecules, 2021, v. 26, n. 19, p. 5753, doi. 10.3390/molecules26195753

By:

Delgado-Vélez, Manuel;
Quesada, Orestes;
Villalobos-Santos, Juan C.;
Maldonado-Hernández, Rafael;
Asmar-Rovira, Guillermo;
Stevens, Raymond C.;
Lasalde-Dominicci, José Antonio

Publication type:

Article

Molecular Targets of Cannabidiol in Experimental Models of Neurological Disease.

Published in:

Molecules, 2020, v. 25, n. 21, p. 5186, doi. 10.3390/molecules25215186

By:

Silvestro, Serena;
Schepici, Giovanni;
Bramanti, Placido;
Mazzon, Emanuela;
Cardona, Francesca

Publication type:

Article

Minimal Structural Changes Determine Full and Partial Nicotinic Receptor Agonist Activity for Nicotine Analogues.

Published in:

Molecules, 2019, v. 24, n. 15, p. 2684, doi. 10.3390/molecules24152684

By:

Gonzalez-Gutierrez, Juan Pablo;
Hodar, Martin;
Viscarra, Franco;
Paillali, Pablo;
Guerra-Díaz, Nicolás;
Pessoa-Mahana, Hernán;
Hernández-Morantes, Juan José;
Pérez-Sánchez, Horacio;
Bermúdez, Isabel;
Reyes-Parada, Miguel;
Iturriaga-Vásquez, Patricio

Publication type:

Article

Pathogenesis and Targeted Therapy of Epilepsy.

Published in:

Biomedicines, 2022, v. 10, n. 12, p. 3134, doi. 10.3390/biomedicines10123134

By:

N'Gouemo, Prosper

Publication type:

Article

UFR2709, an Antagonist of Nicotinic Acetylcholine Receptors, Delays the Acquisition and Reduces Long-Term Ethanol Intake in Alcohol-Preferring UChB Bibulous Rats.

Published in:

Biomedicines, 2022, v. 10, n. 7, p. N.PAG, doi. 10.3390/biomedicines10071482

By:

Gálvez, Gabriel;
González-Gutiérrez, Juan Pablo;
Hödar-Salazar, Martín;
Sotomayor-Zárate, Ramón;
Quintanilla, María Elena;
Quilaqueo, María Elena;
Rivera-Meza, Mario;
Iturriaga-Vásquez, Patricio

Publication type:

Article

P2Y1 purinergic receptor identified as a diabetes target in a small-molecule screen to reverse circadian _-cell failure.

Published in:

eLife, 2022, p. 1, doi. 10.7554/eLife.75132

By:

Marcheva, Biliana;
Weidemann, Benjamin J.;
Akihiko Taguchi;
Perelis, Mark;
Ramsey, Kathryn Moynihan;
Newman, Marsha V.;
Yumiko Kobayashi;
Chiaki Omura;
Fox, Jocelyn E. Manning;
Haopeng Lin;
Macdonald, Patrick E.;
Bass, Joseph

Publication type:

Article

Markov state models of proton- and pore-dependent activation in a pentameric ligand-gated ion channel.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.68369

By:

Bergh, Cathrine;
Heusser, Stephanie A.;
Howard, Rebecca;
Lindahl, Erik

Publication type:

Article