Works matching DE "LEUKOTRIENE A4 hydrolase"

Results: 13

A remarkable activity of human leukotriene A hydrolase (LTA4H) toward unnatural amino acids.

Published in:

Amino Acids, 2014, v. 46, n. 5, p. 1313, doi. 10.1007/s00726-014-1694-2

By:

Byzia, Anna;
Haeggström, Jesper;
Salvesen, Guy;
Drag, Marcin

Publication type:

Article

Evaluating the Impact of LTA4H Genotype and Immune Status on Survival From Tuberculous Meningitis.

Published in:

2017

By:

Fava, Vinicius M.;
Schurr, Erwin

Publication type:

journal article

Hybrid Receptor-Bound/MM-GBSA-Per-residue Energy-Based Pharmacophore Modelling: Enhanced Approach for Identification of Selective LTA4H Inhibitors as Potential Anti-inflammatory Drugs.

Published in:

Cell Biochemistry & Biophysics, 2017, v. 75, n. 1, p. 35, doi. 10.1007/s12013-016-0772-3

By:

Appiah-Kubi, Patrick;
Soliman, Mahmoud

Publication type:

Article

LTA4H regulates cell cycle and skin carcinogenesis.

Published in:

Carcinogenesis, 2017, v. 38, n. 7, p. 728, doi. 10.1093/carcin/bgx049

By:

Naomi Oi;
Hiroyuki Yamamoto;
Langfald, Alyssa;
Bai, Ruihua;
Mee-Hyun Lee;
Bode, Ann M.;
Zigang Dong

Publication type:

Article

Ligand‐based Modeling for the Prediction of Pharmacophore Features for Multi‐targeted Inhibition of the Arachidonic Acid Cascade.

Published in:

Molecular Informatics, 2018, v. 37, n. 3, p. 1, doi. 10.1002/minf.201700073

By:

Saroj Devi, Nisha;
Shanmugam, Rajasekar;
Ghorai, Jayanta;
Ramanan, Meera;
Anbarasan, Pazhamalai;
Doble, Mukesh

Publication type:

Article

Common Polymorphisms in the 5-Lipoxygenase Pathway and Risk of Incident Myocardial Infarction: A Danish Case-Cohort Study.

Published in:

PLoS ONE, 2016, v. 11, n. 11, p. 1, doi. 10.1371/journal.pone.0167217

By:

Gammelmark, Anders;
Nielsen, Michael S.;
Lundbye-Christensen, Søren;
Tjønneland, Anne;
Schmidt, Erik B.;
Overvad, Kim

Publication type:

Article

Role of LTA4H Polymorphism in Tuberculosis-Associated Immune Reconstitution Inflammatory Syndrome Occurrence and Clinical Severity in Patients Infected with HIV.

Published in:

PLoS ONE, 2016, v. 11, n. 9, p. 1, doi. 10.1371/journal.pone.0163298

By:

Narendran, Gopalan;
Kavitha, Dhanasekaran;
Karunaianantham, Ramesh;
Gil-Santana, Leonardo;
Almeida-Junior, Jilson L.;
Reddy, Sirasanambatti Devarajulu;
Kumar, Marimuthu Makesh;
Hemalatha, Haribabu;
Jayanthi, Nagesh Nalini;
Ravichandran, Narayanan;
Krishnaraja, Raja;
Prabhakar, Angamuthu;
Manoharan, Tamizhselvan;
Nithyananthan, Lokeswaran;
Arjunan, Gunasundari;
Natrajan, Mohan;
Swaminathan, Soumya;
Andrade, Bruno B.

Publication type:

Article

Efferent Duct Toxicity with Secondary Testicular Changes in Rats Following Administration of a Novel Leukotriene A4 Hydrolase Inhibitor.

Published in:

Toxicologic Pathology, 2012, v. 40, n. 5, p. 705, doi. 10.1177/0192623312441412

By:

La, David K.;
Creasy, Dianne M.;
Hess, Rex A.;
Baxter, Elizabeth;
Pereira, Marcia E.;
Johnson, Charles A.;
Vinken, Petra;
Snook, Sandra S.

Publication type:

Article

In Silico Modeling of the Molecular Structure and Binding of Leukotriene A4 into Leukotriene A4 Hydrolase.

Published in:

Chemical Biology & Drug Design, 2012, v. 80, n. 6, p. 902, doi. 10.1111/cbdd.12037

By:

Paz, Paula B.;
Vega-Hissi, Esteban G.;
Estrada, Mario R.;
Garro Martinez, Juan C.

Publication type:

Article

Enantioselective Enzymes by Computational Design and In Silico Screening.

Published in:

Angewandte Chemie, 2015, v. 127, n. 12, p. 3797, doi. 10.1002/ange.201411415

By:

Wijma, Hein J.;
Floor, Robert J.;
Bjelic, Sinisa;
Marrink, Siewert J.;
Baker, David;
Janssen, Dick B.

Publication type:

Article

An extracellular matrix fragment drives epithelial remodeling and airway hyperresponsiveness.

Published in:

Science Translational Medicine, 2018, v. 10, n. 455, p. 1, doi. 10.1126/scitranslmed.aaq0693

By:

Patel, Dhiren F.;
Peiró, Teresa;
Shoemark, Amelia;
Akthar, Samia;
Walker, Simone A.;
Grabiec, Aleksander M.;
Jackson, Patricia L.;
Hussell, Tracy;
Gaggar, Amit;
Xu, Xin;
Trevor, Jennifer L.;
Li, Jindong;
Steele, Chad;
Tavernier, Gael;
Blalock, J. Edwin;
Niven, Robert M.;
Gregory, Lisa G.;
Simpson, Angela;
Lloyd, Clare M.;
Snelgrove, Robert J.

Publication type:

Article

Structural Origins for the Loss of Catalytic Activities of Bifunctional Human LTA4H Revealed through Molecular Dynamics Simulations.

Published in:

PLoS ONE, 2012, v. 7, n. 7, p. 1, doi. 10.1371/journal.pone.0041063

By:

Thangapandian, Sundarapandian;
John, Shalini;
Lazar, Prettina;
Choi, Sun;
Lee, Keun Woo

Publication type:

Article

Molecular Dynamics Simulation Study and Hybrid Pharmacophore Model Development in Human LTA4H Inhibitor Design.

Published in:

PLoS ONE, 2012, v. 7, n. 4, p. 1, doi. 10.1371/journal.pone.0034593

By:

Thangapandian, Sundarapandian;
John, Shalini;
Arooj, Mahreen;
Keun Woo Lee

Publication type:

Article