Works matching DE "LEUKEMIA etiology"

Results: 506

Overexpression of Hiwi Inhibits the Cell Growth of Chronic Myeloid Leukemia K562 Cells and Enhances Their Chemosensitivity to Daunomycin.

Published in:

Cell Biochemistry & Biophysics, 2015, v. 73, n. 1, p. 129, doi. 10.1007/s12013-015-0668-7

By:

Wang, Yalin;
Jiang, Yan;
Bian, Cuicui;
Dong, Yi;
Ma, Chao;
Hu, Xiaolin;
Liu, Ziling

Publication type:

Article

Intraclonal Cell Expansion and Selection Driven by B Cell Receptor in Chronic Lymphocytic Leukemia.

Published in:

Molecular Medicine, 2011, v. 17, n. 7/8, p. 834, doi. 10.2119/molmed.2011.00047

By:

Colombo, Monica;
Cutrona, Giovanna;
Reverberi, Daniele;
Fabris, Sonia;
Neri, Antonino;
Fabbi, Marina;
Quintana, Giovanni;
Quarta, Giovanni;
Ghiotto, Fabio;
Fais, Franco;
Ferrarini, Manlio

Publication type:

Article

IN BRIEF.

Published in:: Nature Reviews Immunology, 2003, v. 3, n. 8, p. 603, doi. 10.1038/nri1170
Publication type:: Article

The State of the Art in the Pathogenesis of ATL and New Potential Targets Associated with HTLV-1 and ATL.

Published in:

International Reviews of Immunology, 2007, v. 26, n. 5/6, p. 249, doi. 10.1080/08830180701709817

By:

Murata, Ken;
Yamada, Yasuaki

Publication type:

Article

Integrated decoding hematopoiesis and leukemogenesis using single-cell sequencing and its medical implication.

Published in:

Cell Discovery, 2021, v. 7, n. 1, p. 1, doi. 10.1038/s41421-020-00223-4

By:

Qin, Pengfei;
Pang, Yakun;
Hou, Wenhong;
Fu, Ruiqing;
Zhang, Yingchi;
Wang, Xuefei;
Meng, Guofeng;
Liu, Qifa;
Zhu, Xiaofan;
Hong, Ni;
Cheng, Tao;
Jin, Wenfei

Publication type:

Article

New insights into childhood leukemia etiology.

Published in:

European Journal of Epidemiology, 2015, v. 30, n. 12, p. 1225, doi. 10.1007/s10654-015-0115-5

By:

Wiemels, Joe

Publication type:

Article

Perinatal risk factors for acute myeloid leukemia.

Published in:

European Journal of Epidemiology, 2015, v. 30, n. 12, p. 1277, doi. 10.1007/s10654-015-0063-0

By:

Crump, Casey;
Sundquist, Jan;
Sieh, Weiva;
Winkleby, Marilyn;
Sundquist, Kristina

Publication type:

Article

Crucial role of the Rap G protein signal in Notch activation and leukemogenicity of T-cell acute lymphoblastic leukemia.

Published in:

Scientific Reports, 2015, p. 7978, doi. 10.1038/srep07978

By:

Doi, Keiko;
Imai, Takahiko;
Kressler, Christopher;
Yagita, Hideo;
Agata, Yasutoshi;
Vooijs, Marc;
Hamazaki, Yoko;
Inoue, Joe;
Minato, Nagahiro

Publication type:

Article

BAALC potentiates oncogenic ERK pathway through interactions with MEKK1 and KLF4.

Published in:

2015

By:

Morita, K;
Masamoto, Y;
Kataoka, K;
Koya, J;
Kagoya, Y;
Yashiroda, H;
Sato, T;
Murata, S;
Kurokawa, M

Publication type:

journal article

Loss of Dnmt3a and endogenous Kras<sup>G12D/+</sup> cooperate to regulate hematopoietic stem and progenitor cell functions in leukemogenesis.

Published in:

Leukemia (08876924), 2015, v. 29, n. 9, p. 1847, doi. 10.1038/leu.2015.85

By:

Chang, Y-I;
You, X;
Kong, G;
Ranheim, E A;
Wang, J;
Du, J;
Liu, Y;
Zhou, Y;
Ryu, M-J;
Zhang, J

Publication type:

Article

Runx1 is required for hematopoietic defects and leukemogenesis in Cbfb-MYH11 knock-in mice.

Published in:

Leukemia (08876924), 2015, v. 29, n. 8, p. 1771, doi. 10.1038/leu.2015.58

By:

Hyde, R K;
Zhao, L;
Alemu, L;
Liu, P P

Publication type:

Article

The DEK oncoprotein and its emerging roles in gene regulation.

Published in:

Leukemia (08876924), 2015, v. 29, n. 8, p. 1632, doi. 10.1038/leu.2015.72

By:

Sandén, C;
Gullberg, U

Publication type:

Article

AML1/ETO cooperates with HIF1α to promote leukemogenesis through DNMT3a transactivation.

Published in:

Leukemia (08876924), 2015, v. 29, n. 8, p. 1730, doi. 10.1038/leu.2015.56

By:

Gao, X N;
Yan, F;
Lin, J;
Gao, L;
Lu, X L;
Wei, S C;
Shen, N;
Pang, J X;
Ning, Q Y;
Komeno, Y;
Deng, A L;
Xu, Y H;
Shi, J L;
Li, Y H;
Zhang, D E;
Nervi, C;
Liu, S J;
Yu, L

Publication type:

Article

Mutated Ptpn11 alters leukemic stem cell frequency and reduces the sensitivity of acute myeloid leukemia cells to Mcl1 inhibition.

Published in:

Leukemia (08876924), 2015, v. 29, n. 6, p. 1290, doi. 10.1038/leu.2015.18

By:

Chen, L;
Chen, W;
Mysliwski, M;
Serio, J;
Ropa, J;
Abulwerdi, F A;
Chan, R J;
Patel, J P;
Tallman, M S;
Paietta, E;
Melnick, A;
Levine, R L;
Abdel-Wahab, O;
Nikolovska-Coleska, Z;
Muntean, A G

Publication type:

Article

PTPROt-mediated regulation of p53/Foxm1 suppresses leukemic phenotype in a CLL mouse model.

Published in:

Leukemia (08876924), 2015, v. 29, n. 6, p. 1350, doi. 10.1038/leu.2014.341

By:

Motiwala, T;
Kutay, H;
Zanesi, N;
Frissora, F W;
Mo, X;
Muthusamy, N;
Jacob, S T

Publication type:

Article

A critical role for CRM1 in regulating HOXA gene transcription in CALM-AF10 leukemias.

Published in:

Leukemia (08876924), 2015, v. 29, n. 2, p. 423, doi. 10.1038/leu.2014.221

By:

Conway, A E;
Haldeman, J M;
Wechsler, D S;
Lavau, C P

Publication type:

Article

Dominant-negative Ikaros cooperates with BCR-ABL1 to induce human acute myeloid leukemia in xenografts.

Published in:

Leukemia (08876924), 2015, v. 29, n. 1, p. 177, doi. 10.1038/leu.2014.150

By:

Theocharides, A P A;
Dobson, S M;
Laurenti, E;
Notta, F;
Voisin, V;
Cheng, P-Y;
Yuan, J S;
Guidos, C J;
Minden, M D;
Mullighan, C G;
Torlakovic, E;
Dick, J E

Publication type:

Article

PRPF8 defects cause missplicing in myeloid malignancies.

Published in:

Leukemia (08876924), 2015, v. 29, n. 1, p. 126, doi. 10.1038/leu.2014.144

By:

Kurtovic-Kozaric, A;
Przychodzen, B;
Singh, J;
Konarska, M M;
Clemente, M J;
Otrock, Z K;
Nakashima, M;
Hsi, E D;
Yoshida, K;
Shiraishi, Y;
Chiba, K;
Tanaka, H;
Miyano, S;
Ogawa, S;
Boultwood, J;
Makishima, H;
Maciejewski, J P;
Padgett, R A

Publication type:

Article

Protein kinase N3 deficiency impedes PI3-kinase pathway-driven leukemogenesis without affecting normal hematopoiesis.

Published in:

Leukemia (08876924), 2015, v. 29, n. 1, p. 255, doi. 10.1038/leu.2014.278

By:

Kraus, M;
Dolinski, B;
Rosahl, T W;
Magee, J A

Publication type:

Article

Pre-leukemic evolution of hematopoietic stem cells: the importance of early mutations in leukemogenesis.

Published in:

Leukemia (08876924), 2014, v. 28, n. 12, p. 2276, doi. 10.1038/leu.2014.211

By:

Corces-Zimmerman, M R;
Majeti, R

Publication type:

Article

Impaired hematopoietic differentiation of RUNX1-mutated induced pluripotent stem cells derived from FPD/AML patients.

Published in:

Leukemia (08876924), 2014, v. 28, n. 12, p. 2344, doi. 10.1038/leu.2014.136

By:

Sakurai, M;
Kunimoto, H;
Watanabe, N;
Fukuchi, Y;
Yuasa, S;
Yamazaki, S;
Nishimura, T;
Sadahira, K;
Fukuda, K;
Okano, H;
Nakauchi, H;
Morita, Y;
Matsumura, I;
Kudo, K;
Ito, E;
Ebihara, Y;
Tsuji, K;
Harada, Y;
Harada, H;
Okamoto, S

Publication type:

Article

The leukemogenicity of Hoxa9 depends on alternative splicing.

Published in:

Leukemia (08876924), 2014, v. 28, n. 9, p. 1838, doi. 10.1038/leu.2014.74

By:

Stadler, C R;
Vegi, N;
Mulaw, M A;
Edmaier, K E;
Rawat, V P S;
Dolnik, A;
Bullinger, L;
Heilmeier, B;
Quintanilla-Fend, L;
Spiekermann, K;
Hiddemann, W;
Döhner, K;
Döhner, H;
Feuring-Buske, M;
Buske, C

Publication type:

Article

BCR-ABL1-positive microvesicles transform normal hematopoietic transplants through genomic instability: implications for donor cell leukemia.

Published in:

Leukemia (08876924), 2014, v. 28, n. 8, p. 1666, doi. 10.1038/leu.2014.51

By:

Zhu, X;
You, Y;
Li, Q;
Zeng, C;
Fu, F;
Guo, A;
Zhang, H;
Zou, P;
Zhong, Z;
Wang, H;
Wu, Y;
Kong, F;
Chen, Z

Publication type:

Article

The DNA double-strand break response is abnormal in myeloblasts from patients with therapy-related acute myeloid leukemia.

Published in:

Leukemia (08876924), 2014, v. 28, n. 6, p. 1242, doi. 10.1038/leu.2013.368

By:

Jacoby, M A;
De Jesus Pizarro, R E;
Shao, J;
Koboldt, D C;
Fulton, R S;
Zhou, G;
Wilson, R K;
Walter, M J

Publication type:

Article

Excess congenital non-synonymous variation in leukemia-associated genes in MLL− infant leukemia: a Children's Oncology Group report.

Published in:

Leukemia (08876924), 2014, v. 28, n. 6, p. 1235, doi. 10.1038/leu.2013.367

By:

Valentine, M C;
Linabery, A M;
Chasnoff, S;
Hughes, A E O;
Mallaney, C;
Sanchez, N;
Giacalone, J;
Heerema, N A;
Hilden, J M;
Spector, L G;
Ross, J A;
Druley, T E

Publication type:

Article

Reprogramming of MLL-AF9 leukemia cells into pluripotent stem cells.

Published in:

Leukemia (08876924), 2014, v. 28, n. 5, p. 1071, doi. 10.1038/leu.2013.304

By:

Liu, Y;
Cheng, H;
Gao, S;
Lu, X;
He, F;
Hu, L;
Hou, D;
Zou, Z;
Li, Y;
Zhang, H;
Xu, J;
Kang, L;
Wang, Q;
Yuan, W;
Cheng, T

Publication type:

Article

PAK-dependent STAT5 serine phosphorylation is required for BCR-ABL-induced leukemogenesis.

Published in:

Leukemia (08876924), 2014, v. 28, n. 3, p. 629, doi. 10.1038/leu.2013.351

By:

Berger, A;
Hoelbl-Kovacic, A;
Bourgeais, J;
Hoefling, L;
Warsch, W;
Grundschober, E;
Uras, I Z;
Menzl, I;
Putz, E M;
Hoermann, G;
Schuster, C;
Fajmann, S;
Leitner, E;
Kubicek, S;
Moriggl, R;
Gouilleux, F;
Sexl, V

Publication type:

Article

STAT transcription factors in hematopoiesis and leukemogenesis: opportunities for therapeutic intervention.

Published in:

Leukemia (08876924), 2014, v. 28, n. 2, p. 248, doi. 10.1038/leu.2013.192

By:

Dorritie, K A;
McCubrey, J A;
Johnson, D E

Publication type:

Article

Multifaceted roles of GSK-3 and Wnt/β-catenin in hematopoiesis and leukemogenesis: opportunities for therapeutic intervention.

Published in:

Leukemia (08876924), 2014, v. 28, n. 1, p. 15, doi. 10.1038/leu.2013.184

By:

McCubrey, J A;
Steelman, L S;
Bertrand, F E;
Davis, N M;
Abrams, S L;
Montalto, G;
D'Assoro, A B;
Libra, M;
Nicoletti, F;
Maestro, R;
Basecke, J;
Cocco, L;
Cervello, M;
Martelli, A M

Publication type:

Article

NPMc+ and FLT3_ITD mutations cooperate in inducing acute leukaemia in a novel mouse model.

Published in:

Leukemia (08876924), 2013, v. 27, n. 11, p. 2248, doi. 10.1038/leu.2013.114

By:

Mallardo, M;
Caronno, A;
Pruneri, G;
Raviele, P R;
Viale, A;
Pelicci, P G;
Colombo, E

Publication type:

Article

The importance of relative mutant level for evaluating impact on outcome of KIT, FLT3 and CBL mutations in core-binding factor acute myeloid leukemia.

Published in:

Leukemia (08876924), 2013, v. 27, n. 9, p. 1891, doi. 10.1038/leu.2013.186

By:

Allen, C;
Hills, R K;
Lamb, K;
Evans, C;
Tinsley, S;
Sellar, R;
O'Brien, M;
Yin, J L;
Burnett, A K;
Linch, D C;
Gale, R E

Publication type:

Article

Landmark analysis of DNMT3A mutations in hematological malignancies.

Published in:

Leukemia (08876924), 2013, v. 27, n. 7, p. 1573, doi. 10.1038/leu.2013.65

By:

Roller, A;
Grossmann, V;
Bacher, U;
Poetzinger, F;
Weissmann, S;
Nadarajah, N;
Boeck, L;
Kern, W;
Haferlach, C;
Schnittger, S;
Haferlach, T;
Kohlmann, A

Publication type:

Article

Notch signaling in acute promyelocytic leukemia.

Published in:

Leukemia (08876924), 2013, v. 27, n. 7, p. 1548, doi. 10.1038/leu.2013.68

By:

Grieselhuber, N R;
Klco, J M;
Verdoni, A M;
Lamprecht, T;
Sarkaria, S M;
Wartman, L D;
Ley, T J

Publication type:

Article

Novel TAL1 targets beyond protein-coding genes: identification of TAL1-regulated microRNAs in T-cell acute lymphoblastic leukemia.

Published in:

Leukemia (08876924), 2013, v. 27, n. 7, p. 1603, doi. 10.1038/leu.2013.63

By:

Correia, N C;
Durinck, K;
Leite, A P;
Ongenaert, M;
Rondou, P;
Speleman, F;
Enguita, F J;
Barata, J T

Publication type:

Article

CBL-B is required for leukemogenesis mediated by BCR-ABL through negative regulation of bone marrow homing.

Published in:

Leukemia (08876924), 2013, v. 27, n. 5, p. 1146, doi. 10.1038/leu.2012.331

By:

Badger-Brown, K M;
Gillis, L C;
Bailey, M L;
Penninger, J M;
Barber, D L

Publication type:

Article

Differential roles of Kras and Pten in murine leukemogenesis.

Published in:

Leukemia (08876924), 2013, v. 27, n. 5, p. 1210, doi. 10.1038/leu.2012.316

By:

Tang, P;
Gao, C;
Li, A;
Aster, J;
Sun, L;
Chai, L

Publication type:

Article

A pathway from leukemogenic oncogenes and stem cell chemokines to RNA processing via THOC5.

Published in:

Leukemia (08876924), 2013, v. 27, n. 4, p. 932, doi. 10.1038/leu.2012.283

By:

Griaud, F;
Pierce, A;
Gonzalez Sanchez, M B;
Scott, M;
Abraham, S A;
Holyoake, T L;
Tran, D D H;
Tamura, T;
Whetton, A D

Publication type:

Article

SIAH proteins: critical roles in leukemogenesis.

Published in:

Leukemia (08876924), 2013, v. 27, n. 4, p. 792, doi. 10.1038/leu.2012.284

By:

Krämer, O H;
Stauber, R H;
Bug, G;
Hartkamp, J;
Knauer, S K

Publication type:

Article

Suppression of the let-7b microRNA pathway by DNA hypermethylation in infant acute lymphoblastic leukemia with MLL gene rearrangements.

Published in:

Leukemia (08876924), 2013, v. 27, n. 2, p. 389, doi. 10.1038/leu.2012.242

By:

Nishi, M;
Eguchi-Ishimae, M;
Wu, Z;
Gao, W;
Iwabuki, H;
Kawakami, S;
Tauchi, H;
Inukai, T;
Sugita, K;
Hamasaki, Y;
Ishii, E;
Eguchi, M

Publication type:

Article

Role and potential for therapeutic targeting of MYB in leukemia.

Published in:

Leukemia (08876924), 2013, v. 27, n. 2, p. 269, doi. 10.1038/leu.2012.225

By:

Pattabiraman, D R;
Gonda, T J

Publication type:

Article

Leukemia-related chromosomal loss detected in hematopoietic progenitor cells of benzene-exposed workers.

Published in:

Leukemia (08876924), 2012, v. 26, n. 12, p. 2494, doi. 10.1038/leu.2012.143

By:

Zhang, L;
Lan, Q;
Ji, Z;
Li, G;
Shen, M;
Vermeulen, R;
Guo, W;
Hubbard, A E;
McHale, C M;
Rappaport, S M;
Hayes, R B;
Linet, M S;
Yin, S;
Smith, M T;
Rothman, N

Publication type:

Article

Oncogenic fusion E2A-HLF sensitizes t(17;19)-positive acute lymphoblastic leukemia to TRAIL-mediated apoptosis by upregulating the expression of death receptors.

Published in:

Leukemia (08876924), 2012, v. 26, n. 12, p. 2483, doi. 10.1038/leu.2012.139

By:

Zhang, X;
Inukai, T;
Hirose, K;
Akahane, K;
Kuroda, I;
Honna-Oshiro, H;
Kagami, K;
Goi, K;
Nakamura, K;
Kobayashi, M;
Endo, M;
Yagita, H;
Kurosawa, H;
Thomas Look, A;
Honda, H;
Inaba, T;
Nakazawa, S;
Sugita, K

Publication type:

Article

Evidence for a protective role of the STAT5 transcription factor against oxidative stress in human leukemic pre-B cells.

Published in:

Leukemia (08876924), 2012, v. 26, n. 11, p. 2390, doi. 10.1038/leu.2012.112

By:

Cholez, E;
Debuysscher, V;
Bourgeais, J;
Boudot, C;
Leprince, J;
Tron, F;
Brassart, B;
Regnier, A;
Bissac, E;
Pecnard, E;
Gouilleux, F;
Lassoued, K;
Gouilleux-Gruart, V

Publication type:

Article

Newly diagnosed acute lymphoblastic leukemia in China (II): prognosis related to genetic abnormalities in a series of 1091 cases.

Published in:

Leukemia (08876924), 2012, v. 26, n. 7, p. 1507, doi. 10.1038/leu.2012.23

By:

Mi, J-Q;
Wang, X;
Yao, Y;
Lu, H-J;
Jiang, X-X;
Zhou, J-F;
Wang, J-H;
Jiao, B;
Shen, S-H;
Tang, J-Y;
Gu, L-J;
Jiang, H;
Ma, L-Y;
Hao, S-G;
Chen, F-Y;
Xiong, S-M;
Shen, Z-X;
Chen, Z;
Chen, B;
Chen, S-J

Publication type:

Article

Direct interaction of PU.1 with oncogenic transcription factors reduces its serine phosphorylation and promoter binding.

Published in:

Leukemia (08876924), 2012, v. 26, n. 6, p. 1338, doi. 10.1038/leu.2011.331

By:

Seshire, A;
Rößiger, T;
Frech, M;
Beez, S;
Hagemeyer, H;
Puccetti, E

Publication type:

Article

Aberrant expression of RasGRP1 cooperates with gain-of-function NOTCH1 mutations in T-cell leukemogenesis.

Published in:

Leukemia (08876924), 2012, v. 26, n. 5, p. 1038, doi. 10.1038/leu.2011.328

By:

Oki, T;
Kitaura, J;
Watanabe-Okochi, N;
Nishimura, K;
Maehara, A;
Uchida, T;
Komeno, Y;
Nakahara, F;
Harada, Y;
Sonoki, T;
Harada, H;
Kitamura, T

Publication type:

Article

Frequency of leukemic initiating cells does not depend on the xenotransplantation model used.

Published in:

Leukemia (08876924), 2012, v. 26, n. 4, p. 858, doi. 10.1038/leu.2011.250

By:

Vargaftig, J;
Taussig, D C;
Griessinger, E;
Anjos-Afonso, F;
Lister, T A;
Cavenagh, J;
Oakervee, H;
Gribben, J;
Bonnet, D

Publication type:

Article

An oncogenic role of miR-142-3p in human T-cell acute lymphoblastic leukemia (T-ALL) by targeting glucocorticoid receptor-α and cAMP/PKA pathways.

Published in:

Leukemia (08876924), 2012, v. 26, n. 4, p. 769, doi. 10.1038/leu.2011.273

By:

Lv, M;
Zhang, X;
Jia, H;
Li, D;
Zhang, B;
Zhang, H;
Hong, M;
Jiang, T;
Jiang, Q;
Lu, J;
Huang, X;
Huang, B

Publication type:

Article

c-Myb and its target Bmi1 are required for p190BCR/ABL leukemogenesis in mouse and human cells.

Published in:

Leukemia (08876924), 2012, v. 26, n. 4, p. 644, doi. 10.1038/leu.2011.264

By:

Waldron, T;
De Dominici, M;
Soliera, A R;
Audia, A;
Iacobucci, I;
Lonetti, A;
Martinelli, G;
Zhang, Y;
Martinez, R;
Hyslop, T;
Bender, T P;
Calabretta, B

Publication type:

Article

Functional role of BAALC in leukemogenesis.

Published in:

2012

By:

Heuser, M;
Berg, T;
Kuchenbauer, F;
Lai, C K;
Park, G;
Fung, S;
Lin, G;
Leung, M;
Krauter, J;
Ganser, A;
Humphries, R K

Publication type:

Letter