Works about LAPATINIB

Results: 283

Cost-effectiveness of lapatinib plus capecitabine in women with HER2+ metastatic breast cancer who have received prior therapy with trastuzumab.

Published in:

European Journal of Health Economics, 2012, v. 13, n. 5, p. 589, doi. 10.1007/s10198-011-0323-1

By:

Delea, Thomas;
Tappenden, Paul;
Sofrygin, Oleg;
Browning, Dominy;
Amonkar, Mayur;
Karnon, Jon;
Walker, Mel;
Cameron, David

Publication type:

Article

Characterization of Locally Excited and Charge‐Transfer States of the Anticancer Drug Lapatinib by Ultrafast Spectroscopy and Computational Studies.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 68, p. 15922, doi. 10.1002/chem.202001336

By:

Vayá, Ignacio;
Andreu, Inmaculada;
Lence, Emilio;
González‐Bello, Concepción;
Consuelo Cuquerella, M.;
Navarrete‐Miguel, Miriam;
Roca‐Sanjuán, Daniel;
Miranda, Miguel A.

Publication type:

Article

Abstracts of Theses Approved for the MSc and PhD Degrees at the Faculty of Medicine, Health Sciences Center, Kuwait University, Kuwait.

Published in:: Medical Principles & Practice, 2013, v. 22, n. 6, p. 609, doi. 10.1159/000355033
Publication type:: Article

Mechanism-based inactivation of CYP450 enzymes: a case study of lapatinib.

Published in:

Drug Metabolism Reviews, 2015, v. 47, n. 1, p. 21, doi. 10.3109/03602532.2014.1003648

By:

Ho, Han Kiat;
Chan, James Chun Yip;
Hardy, Klarissa D.;
Chan, Eric Chun Yong

Publication type:

Article

Liposomal Lapatinib in Combination with Low-Dose Photodynamic Therapy for the Treatment of Glioma.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 12, p. 2214, doi. 10.3390/jcm8122214

By:

Fisher, Carl;
Obaid, Girgis;
Niu, Carolyn;
Foltz, Warren;
Goldstein, Alyssa;
Hasan, Tayyaba;
Lilge, Lothar

Publication type:

Article

CD36: a key mediator of resistance to HER2 inhibitors in breast cancer.

Published in:

2020

By:

Feng, William W.;
Bang, Scott;
Kurokawa, Manabu

Publication type:

Opinion

Lapatinib promotes ovarian cancer cell apoptosis through mROS-HtrA2/Omi pathways.

Published in:

European Journal of Gynaecological Oncology, 2020, v. 41, n. 4, p. 598, doi. 10.31083/j.ejgo.2020.04.5247

By:

Yuqing Yang;
Huimin Zhang;
Weiming Chen;
Xiaoyue Chen;
Xiaolin Yu

Publication type:

Article

Efficacy of lapatinib combined with capecitabine in patients with HER2-positive metastatic breast cancer in a real-world study.

Published in:

Oncology Letters, 2020, v. 20, n. 6, p. N.PAG, doi. 10.3892/ol.2020.12241

By:

Gui, Xinyu;
Li, Huiping;
Yan, Ying;
Zhang, Ruyan

Publication type:

Article

Effects of lapatinib on cell proliferation and apoptosis in NB4 cells.

Published in:

Oncology Letters, 2018, v. 15, n. 1, p. 235, doi. 10.3892/ol.2017.7342

By:

Liu, Lu;
Zhong, Liang;
Zhao, Yi;
Chen, Min;
Yao, Shifei;
Li, Lianwen;
Xiao, Chunlan;
Shan, Zhiling;
Gan, Liugen;
Xu, Ting;
Liu, Beizhong

Publication type:

Article

Inhibition of Hes1 enhances lapatinib sensitivity in gastric cancer sphere-forming cells.

Published in:

Oncology Letters, 2017, v. 14, n. 4, p. 3989, doi. 10.3892/ol.2017.6683

By:

LUCHUN LI;
YAN LI;
LULU WANG;
ZHIJUAN WU;
HUIWEN MA;
JIANGHE SHAO;
DAIRONG LI;
HUIQING YU;
WEIQI NIAN;
DONGLIN WANG

Publication type:

Article

Lapatinib-induced mesenchymal-epithelial transition in squamous cell carcinoma cells correlates with unexpected alteration of β-catenin expression.

Published in:

Oncology Letters, 2016, v. 11, n. 4, p. 2715, doi. 10.3892/ol.2016.4293

By:

UMBREIT, CLAUDIA;
ERBEN, PHILIPP;
FABER, ANNE;
HOFHEINZ, RALF-DIETER;
SCHULTZ, JOHANNES DAVID;
HOERMANN, KARL;
WENZEL, ANGELA

Publication type:

Article

Circulating microRNA profile predicts disease progression in patients receiving second-line treatment of lapatinib and capecitabine for metastatic pancreatic cancer.

Published in:

Oncology Letters, 2016, v. 11, n. 3, p. 1645, doi. 10.3892/ol.2016.4101

By:

TIAN, XUEFEI;
SHIVAPURKAR, NARAYAN;
ZHENG WU;
HWANG, JIMMY J.;
PISHVAIAN, MICHAEL J.;
WEINER, LOUIS M.;
LEY, LISA;
DAN ZHOU;
ZHI, XIULING;
WELLSTEIN, ANTON;
MARSHALL, JOHN L.;
HE, AIWU RUTH

Publication type:

Article

Lapatinib combined with neoadjuvant paclitaxel-trastuzumab-based chemotherapy in patients with human epidermal growth factor receptor 2-positive breast cancer: A meta-analysis of randomized controlled trials.

Published in:

Oncology Letters, 2015, v. 9, n. 3, p. 1351, doi. 10.3892/ol.2015.2848

By:

JINZHONG SUN;
CHUANG CHEN;
XIAOLI YAO;
SHENGRONG SUN

Publication type:

Article

Efficacy of lapatinib monotherapy on occult breast cancer presenting with cutaneous metastases: A case report.

Published in:

2014

By:

EIICHIRO NOGUCHI;
TAKAKO KAMIO;
HIDENORI KAMIO;
HIROKO MIURA;
MASAKO TAMAKI;
MASAKO NISHIZAWA;
KEI AOYAMA;
TETSUYA OOCHI;
SHINGO KAMEOKA

Publication type:

Case Study

Physicochemical Characterization and Cyclodextrin Complexation of the Anticancer Drug Lapatinib.

Published in:

Journal of Chemistry, 2017, p. 1, doi. 10.1155/2017/4537632

By:

Tóth, Gergő;
Jánoska, Ádám;
Völgyi, Gergely;
Szabó, Zoltán-István;
Orgován, Gábor;
Mirzahosseini, Arash;
Noszál, Béla

Publication type:

Article

Neuroprotective Effects of the Anti-cancer Drug Lapatinib Against Epileptic Seizures via Suppressing Glutathione Peroxidase 4-Dependent Ferroptosis.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.601572

By:

Jia, Ji-Ning;
Yin, Xi-Xi;
Li, Qin;
Guan, Qi-Wen;
Yang, Nan;
Chen, Kang-Ni;
Zhou, Hong-Hao;
Mao, Xiao-Yuan

Publication type:

Article

Lapatinib Activates the Kelch-Like ECH-Associated Protein 1-Nuclear Factor Erythroid 2-Related Factor 2 Pathway in HepG2 Cells.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. 1, doi. 10.3389/fphar.2020.00944

By:

Roos, Noëmi Johanna;
Aliu, Diell;
Bouitbir, Jamal;
Krähenbühl, Stephan

Publication type:

Article

Mechanisms, monitoring, and management of tyrosine kinase inhibitors-associated cardiovascular toxicities.

Published in:

OncoTargets & Therapy, 2018, v. 11, p. 6227, doi. 10.2147/OTT.S170138

By:

Chaar, Maher;
Kamta, Jeff;
Ait-Oudhia, Sihem

Publication type:

Article

Everolimus enhances cellular cytotoxicity of lapatinib via the eukaryotic elongation factor-2 kinase pathway in nasopharyngeal carcinoma cells.

Published in:

OncoTargets & Therapy, 2016, v. 9, p. 6195, doi. 10.2147/OTT.S115309

By:

Lin Liu;
Zhi-Hui Wang;
Jun Han;
Con Tang;
Nan Chen;
Zhong Lin;
Pei-Jian Peng

Publication type:

Article

The efficiency and safety of trastuzumab and lapatinib added to neoadjuvant chemotherapy in Her2-positive breast cancer patients: a randomized meta-analysis.

Published in:

OncoTargets & Therapy, 2016, v. 9, p. 3233, doi. 10.2147/OTT.S106055

By:

Zhe-Ling Chen;
Yan-Wei Shen;
Shu-Ting Li;
Chun-Li Li;
Ling-Xiao Zhang;
Jiao Yang;
Meng Lv;
Ya-Yun Lin;
Xin Wang;
Jin Yang

Publication type:

Article

Cytotoxic effect of lapatinib is restricted to human papillomavirus-positive head and neck squamous cell carcinoma cell lines.

Published in:

OncoTargets & Therapy, 2015, v. 8, p. 335, doi. 10.2147/OTT.S68235

By:

Fumagalli, Ingrid;
Dugue, Delphine;
Bibault, Jean Emmanuel;
Clémenson, Céline;
Vozenin, Marie Catherine;
Mondini, Michele;
Deutsch, Eric

Publication type:

Article

Lapatinib for the treatment of breast cancer in the People's Republic of China.

Published in:

OncoTargets & Therapy, 2014, v. 7, p. 1367, doi. 10.2147/OTT.S60586

By:

Hongjiang Wang

Publication type:

Article

Targeted treatment of head and neck squamous-cell carcinoma: potential of lapatinib.

Published in:

OncoTargets & Therapy, 2014, v. 7, p. 245, doi. 10.2147/OTT.S46933

By:

Gandhi, Mitul D.;
Agulnik, Mark

Publication type:

Article

Development and Validation of a Rapid RP-HPLC-DAD Analysis Method for the Simultaneous Quantitation of Paclitaxel and Lapatinib in a Polymeric Micelle Formulation.

Published in:

Scientia Pharmaceutica, 2016, v. 84, n. 2, p. 333, doi. 10.3797/scipharm.1507-03

By:

SAADAT, Ebrahim;
RAVAR, Fatemeh;
DEHGHANKELISHADI, Pouya;
DORKOOSH, Farid A.

Publication type:

Article

Th1 cytokines sensitize HER-expressing breast cancer cells to lapatinib.

Published in:

PLoS ONE, 2019, v. 14, n. 1, p. 1, doi. 10.1371/journal.pone.0210209

By:

Showalter, Loral E.;
Oechsle, Crystal;
Ghimirey, Nirmala;
Steele, Chase;
Czerniecki, Brian J.;
Koski, Gary K.

Publication type:

Article

Lack of acquired resistance in HER2-positive breast cancer cells after long-term HER2 siRNA nanoparticle treatment.

Published in:

PLoS ONE, 2018, v. 13, n. 6, p. 1, doi. 10.1371/journal.pone.0198141

By:

Gu, Shenda;
Ngamcherdtrakul, Worapol;
Reda, Moataz;
Hu, Zhi;
Gray, Joe W.;
Yantasee, Wassana

Publication type:

Article

Structural investigations on mechanism of lapatinib resistance caused by HER-2 mutants.

Published in:

PLoS ONE, 2018, v. 13, n. 2, p. 1, doi. 10.1371/journal.pone.0190942

By:

Verma, Sharad;
Goyal, Sukriti;
Kumari, Anchala;
Singh, Aditi;
Jamal, Salma;
Grover, Abhinav

Publication type:

Article

The Effectiveness of Lapatinib in HER2-Positive Metastatic Breast Cancer Patients Pretreated With Multiline Anti-HER2 Treatment: A Retrospective Study in China.

Published in:

Technology in Cancer Research & Treatment, 2021, p. 1, doi. 10.1177/15330338211037812

By:

Wang, Xinzhao;
Wang, Lin;
Yu, Qian;
Liu, Zhaoyun;
Li, Chao;
Wang, Fukai;
Yu, Zhiyong

Publication type:

Article

The possibility of lapatinib treatment for breast cancer patients with central nervous system metastases. Case study and literature review.

Published in:

Contemporary Oncology / Współczesna Onkologia, 2012, v. 16, n. 6, p. 582, doi. 10.5114/wo.2012.32494

By:

Rolski, Janusz;
Karczmarek-Borowska, Bożenna;
Śmietana, Anetta

Publication type:

Article

Targeting connexin 43 with α-connexin carboxyl-terminal (ACT1) peptide enhances the activity of the targeted inhibitors, tamoxifen and lapatinib, in breast cancer: clinical implication for ACT1.

Published in:

BMC Cancer, 2015, v. 15, n. 1, p. 1, doi. 10.1186/s12885-015-1229-6

By:

Grek, Christina L.;
Rhett, Joshua Matthew;
Bruce, Jaclynn S.;
Abt, Melissa A.;
Ghatnekar, Gautam S.;
Yeh, Elizabeth S.

Publication type:

Article

The role of HGF/MET and FGF/FGFR in fibroblast-derived growth stimulation and lapatinib-resistance of esophageal squamous cell carcinoma.

Published in:

BMC Cancer, 2015, v. 15, n. 1, p. 1, doi. 10.1186/s12885-015-1065-8

By:

Shin Saito;
Kazue Morishima;
Takashi Ui;
Hiroko Hoshino;
Daisuke Matsubara;
Shumpei Ishikawa;
Hiroyuki Aburatani;
Masashi Fukayama;
Yoshinori Hosoya;
Naohiro Sata;
Lefor, Alan K.;
Yoshikazu Yasuda;
Toshiro Niki

Publication type:

Article

Effectivity of pazopanib treatment in orthotopic models of human testicular germ cell tumors.

Published in:

2013

By:

Juliachs, Mercè;
Vidal, August;
del Muro, Xavier Garcia;
Piulats, Josep M.;
Condom, Enric;
Casanovas, Oriol;
Graupera, Mariona;
Germà, Jose R.;
Villanueva, Alberto;
Viñals, Francesc

Publication type:

journal article

OSU-03012 sensitizes breast cancers to lapatinib-induced cell killing: a role for Nck1 but not Nck2.

Published in:

BMC Cancer, 2013, v. 13, n. 1, p. 1, doi. 10.1186/1471-2407-13-256

By:

Winston West, N.;
Garcia-Vargas, Aileen;
Chalfant, Charles E.;
Park, Margaret A.

Publication type:

Article

The ErbB3-binding protein EBP1 modulates lapatinib sensitivity in prostate cancer cells.

Published in:

Molecular & Cellular Biochemistry, 2015, v. 405, n. 1/2, p. 177, doi. 10.1007/s11010-015-2409-z

By:

Awasthi, Smita;
Ezelle, Heather;
Hassel, Bret;
Hamburger, Anne

Publication type:

Article

Optimal tolerability and high efficacy of a modified schedule of lapatinib-capecitabine in advanced breast cancer patients.

Published in:

Journal of Cancer Research & Clinical Oncology, 2014, v. 140, n. 2, p. 221, doi. 10.1007/s00432-013-1556-4

By:

Gamucci, T.;
Moscetti, L.;
Mentuccia, L.;
Pizzuti, L.;
Mauri, M.;
Zampa, G.;
Pavese, I.;
Sperduti, I.;
Vaccaro, A.;
Vici, P.

Publication type:

Article

Brèves de l'AERIO.

Published in:

Oncologie (Tech Science Press), 2014, v. 16, n. 1, p. 69, doi. 10.1007/s10269-014-2367-6

By:

Cochereau, D.;
Espie, M.;
Hadoux, J.;
Loriot, Y.

Publication type:

Article

Brèves de l'AERIO.

Published in:: Oncologie (Tech Science Press), 2012, v. 14, n. 12, p. 687, doi. 10.1007/s10269-012-2236-8
Publication type:: Article

QBD-Powered Design and Optimization of Nanostructured Lipid Carriers Loaded with BCS class IV Anticancer Drug.

Published in:

Indian Journal of Pharmaceutical Education & Research, 2024, v. 58, p. S828, doi. 10.5530/ijper.58.3s.84

By:

Haritha, Pamujula Naga;
Janakiraman, Kunchithapatham;
Madhav, Katla Venu;
Kumar Chaitanya, Padavala Sunil

Publication type:

Article

Dual HER2 blockade with lapatinib and trastuzumab in combination with chemotherapy in metastatic gastroesophageal adenocarcinoma.

Published in:

Clinical Case Reports, 2021, v. 9, n. 4, p. 2264, doi. 10.1002/ccr3.4009

By:

Cheong, E. Von;
Ho, Gwo Fuang

Publication type:

Article

Dual targeting micelles loaded with paclitaxel and lapatinib for combinational therapy of brain metastases from breast cancer.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-06677-8

By:

Lu, Heng;
Chen, Tianran;
Wang, Yiran;
He, Yuwei;
Pang, Zhiqing;
Wang, Yajie

Publication type:

Article

Lapatinib as first-line treatment for muscle-invasive urothelial carcinoma in dogs.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-021-04229-0

By:

Maeda, Shingo;
Sakai, Kosei;
Kaji, Kenjiro;
Iio, Aki;
Nakazawa, Maho;
Motegi, Tomoki;
Yonezawa, Tomohiro;
Momoi, Yasuyuki

Publication type:

Article

Human induced pluripotent stem cell-derived platelets loaded with lapatinib effectively target HER2+ breast cancer metastasis to the brain.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-96351-2

By:

Bhan, Arunoday;
Ansari, Khairul;
Chen, Mike Y.;
Jandial, Rahul

Publication type:

Article

Effect of lapatinib on oral digoxin absorption in patients.

Published in:

Clinical Pharmacology in Drug Development, 2015, v. 4, n. 6, p. 449, doi. 10.1002/cpdd.189

By:

Koch, Kevin M.;
Smith, Deborah A.;
Botbyl, Jeff;
Arya, Nikita;
Briley, Linda P.;
Cartee, Leanne;
White, Jane Holshouser;
Beyer, Jennifer;
Dar, Mohammed M.;
Chung, Hyun Choel;
Chu, Quincy;
Bang, Yung‐Jue

Publication type:

Article

Bioequivalence study with lapatinib powder for oral suspension and the original tablet formulation in cancer patients.

Published in:

Clinical Pharmacology in Drug Development, 2015, v. 4, n. 3, p. 203, doi. 10.1002/cpdd.139

By:

Koch, Kevin M.;
Ferron-Brady, Geraldine;
Lemmon, Colleen;
Cartee, Leanne;
Hollyfield, Hedy;
D'Amelio, Anthony M.;
Piepszak, Alexandra;
Swaby, Ramona F.;
Curran, David;
Arya, Niki

Publication type:

Article

Survivin in Insulin-Like Growth Factor-Induced Resistance to Lapatinib in Head and Neck Squamous Carcinoma Cells.

Published in:

Frontiers in Oncology, 2019, p. N.PAG, doi. 10.3389/fonc.2019.00013

By:

Lehman, Christine E.;
Mendez, Rolando E.;
Dougherty, Michael I.;
Allak, Amir;
Adejumo, Oluwayemisi L.;
Taniguchi, Linnea E.;
Khalil, Ashraf;
Gioeli, Daniel G.;
Jameson, Mark J.

Publication type:

Article

Assay of lapatinib in murine models of cigarette smoke carcinogenesis.

Published in:

Carcinogenesis, 2014, v. 35, n. 10, p. 2300, doi. 10.1093/carcin/bgu154

By:

Balansky, Roumen;
Izzotti, Alberto;
D’Agostini, Francesco;
Longobardi, Mariagrazia;
Micale, Rosanna T.;
La Maestra, Sebastiano;
Camoirano, Anna;
Ganchev, Gancho;
Iltcheva, Marietta;
Steele, Vernon E.;
De Flora, Silvio

Publication type:

Article

Determination of Lapatinib in Bulk and Tablet Dosage Form using Ultraviolet Spectrophotometric and RP-HPLC Analytical Methods.

Published in:

International Journal of Pharmaceutical Investigation, 2021, v. 11, n. 2, p. 208, doi. 10.5530/ijpi.2021.2.37

By:

Mondal, Sumanta;
Biswal, Sabyasachi;
Acharya, Trayambica;
Mondal, Prasenjit;
Bhar, Kausik

Publication type:

Article

PAQR8 promotes breast cancer recurrence and confers resistance to multiple therapies.

Published in:

Breast Cancer Research, 2023, v. 25, n. 1, p. 1, doi. 10.1186/s13058-022-01559-3

By:

Chen, Saisai;
Paul, Matt R.;
Sterner, Christopher J.;
Belka, George K.;
Wang, Dezhen;
Xu, Peining;
Sreekumar, Amulya;
Pan, Tien-chi;
Pant, Dhruv K.;
Makhlin, Igor;
DeMichele, Angela;
Mesaros, Clementina;
Chodosh, Lewis A.

Publication type:

Article

Efficacy of Lapatinib in Therapy-Resistant HER2-Positive Circulating Tumor Cells in Metastatic Breast Cancer.

Published in:

PLoS ONE, 2015, v. 10, n. 6, p. 1, doi. 10.1371/journal.pone.0123683

By:

Agelaki, Sofia;
Kalykaki, Antonia;
Markomanolaki, Harris;
Papadaki, Maria A.;
Kallergi, Galatea;
Hatzidaki, Dora;
Kalbakis, Kostas;
Mavroudis, Dimitrios;
Georgoulias, Vassilis

Publication type:

Article

The Possible Mechanism of Idiosyncratic Lapatinib-Induced Liver Injury in Patients Carrying Human Leukocyte Antigen-DRB1*07:01.

Published in:

PLoS ONE, 2015, v. 10, n. 6, p. 1, doi. 10.1371/journal.pone.0130928

By:

Hirasawa, Makoto;
Hagihara, Katsunobu;
Okudaira, Noriko;
Izumi, Takashi

Publication type:

Article