Works about KYNURENINE

Results: 915

Sex differences in peripheral and central dysregulation of the kynurenine pathway in Parkinson's disease.

Published in:

NPJ Parkinson's Disease, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41531-025-00949-6

By:

Jellen, Leslie C.;
Escobar Galvis, Martha L.;
Sha, Qiong;
Isaguirre, Christine;
Johnson, Amy;
Madaj, Zach;
Lewis, Mechelle M.;
Sheldon, Ryan D.;
Kong, Lan;
Huang, Xuemei;
Brundin, Lena

Publication type:

Article

Tuberculosis and comorbid depression: Association with serum indoleamine 2,3-dioxygenase activity.

Published in:

Indian Journal of Pharmacology, 2025, v. 57, n. 1, p. 21, doi. 10.4103/ijp.ijp_252_23

By:

Rana, Proteesh;
Varughese, Bijo;
Roy, Vandana;
Khanna, Shreshth;
Kapoor, Seema;
Khanna, Ashwani

Publication type:

Article

Nanosensor Detection of an Immunoregulatory Tryptophan Influx/Kynurenine Efflux Cycle.

Published in:

PLoS Biology, 2007, v. 5, n. 10, p. e257, doi. 10.1371/journal.pbio.0050257

By:

Kaper, Thijs;
Looger, Loren L.;
Takanaga, Hitomi;
Platten, Michael;
Steinman, Lawrence;
Frommer, Wolf B.

Publication type:

Article

Indoleamine 2,3-dioxygenase and 3-hydroxykynurenine modifications are found in the neuropathology of Alzheimer's disease.

Published in:

Redox Report, 2010, v. 15, n. 4, p. 161, doi. 10.1179/174329210X12650506623645

By:

Bonda, David J.;
Mailankot, Maneesh;
Stone, Jeremy G.;
Garrett, Matthew R.;
Staniszewska, Magdalena;
Castellani, Rudy J.;
Siedlak, Sandra L.;
Xiongwei Zhu;
Hyoung-gon Lee;
Perry, George;
Nagaraj, Ram H.;
Smith, Mark A.

Publication type:

Article

Changes in kynurenine pathway metabolites after acute psychosocial stress in healthy males: a single-arm pilot study.

Published in:

Stress: The International Journal on the Biology of Stress, 2021, v. 24, n. 6, p. 920, doi. 10.1080/10253890.2021.1959546

By:

La Torre, Danique;
Dalile, Boushra;
de Loor, Henriette;
Van Oudenhove, Lukas;
Verbeke, Kristin

Publication type:

Article

Human indoleamine 2,3-dioxygenase-2 has substrate specificity and inhibition characteristics distinct from those of indoleamine 2,3-dioxygenase-1.

Published in:

Amino Acids, 2014, v. 46, n. 9, p. 2155, doi. 10.1007/s00726-014-1766-3

By:

Pantouris, Georgios;
Serys, Martynas;
Yuasa, Hajime;
Ball, Helen;
Mowat, Christopher

Publication type:

Article

Indoleamine 2,3-dioxygenase 2 (IDO2) and the kynurenine pathway: characteristics and potential roles in health and disease.

Published in:

Amino Acids, 2013, v. 45, n. 6, p. 1319, doi. 10.1007/s00726-013-1602-1

By:

Fatokun, Amos A.;
Hunt, Nicholas H.;
Ball, Helen J.

Publication type:

Article

Identification of l-3-hydroxykynurenine O-sulfate in the buccal gland secretion of the parasitic lamprey, Lethenteron japonicum.

Published in:

Amino Acids, 2012, v. 43, n. 6, p. 2505, doi. 10.1007/s00726-012-1331-x

By:

Odani, Shoji;
Ito, Naoko;
Hasegawa, Mai;
Uchiumi, Toshio;
Hase, Sumihiro

Publication type:

Article

The impact of photo-induced molecular changes of dairy proteins on their ACE-inhibitory peptides and activity.

Published in:

Amino Acids, 2012, v. 43, n. 2, p. 951, doi. 10.1007/s00726-011-1157-y

By:

Kerkaert, Barbara;
Mestdagh, Frédéric;
Cucu, Tatiana;
Shrestha, Kshitij;
Camp, John;
Meulenaer, Bruno

Publication type:

Article

Kynurenine metabolism in health and disease.

Published in:

Amino Acids, 2011, v. 41, n. 5, p. 1173, doi. 10.1007/s00726-010-0787-9

By:

Kolodziej, Lukasz;
Paleolog, Ewa;
Williams, Richard

Publication type:

Article

Kynurenines in the mammalian brain: when physiology meets pathology.

Published in:

Nature Reviews Neuroscience, 2012, v. 13, n. 7, p. 465, doi. 10.1038/nrn3257

By:

Schwarcz, Robert;
Bruno, John P.;
Muchowski, Paul J.;
Wu, Hui-Qiu

Publication type:

Article

Comprehensive behavioral analysis of tryptophan 2,3‐dioxygenase (Tdo2) knockout mice.

Published in:

Neuropsychopharmacology Reports, 2018, v. 38, n. 2, p. 52, doi. 10.1002/npr2.12006

By:

Hattori, Satoko;
Takao, Keizo;
Funakoshi, Hiroshi;
Miyakawa, Tsuyoshi

Publication type:

Article

A8 DIETARY TRYPTOPHAN MODULATES KYNURENINE AND INDOLE PRODUCTION IN HEALTHY INDIVIDUALS.

Published in:

Journal of the Canadian Association of Gastroenterology, 2021, v. 4, p. 9, doi. 10.1093/jcag/gwab002.007

By:

Rueda, G H;
Causada-Calo, N;
Borojevic, R;
Nardelli, A;
Constante, M;
Loonen, L;
Wells, J;
Sokol, H;
Verdu, E;
Bercik, P

Publication type:

Article

Potato- An Important Source of Nutritional Kynurenic Acid.

Published in:

Plant Foods for Human Nutrition, 2012, v. 67, n. 1, p. 17, doi. 10.1007/s11130-012-0283-3

By:

Turski, Michal;
Kamiński, Piotr;
Zgrajka, Wojciech;
Turska, Monika;
Turski, Waldemar

Publication type:

Article

Micromolar Brain Levels of Kynurenic Acid are Associated with a Disruption of Auditory Sensory Gating in the Rat.

Published in:

Neuropsychopharmacology, 2003, v. 28, n. 8, p. 1454, doi. 10.1038/sj.npp.1300188

By:

Shepard, Paul D.;
Joy, Brian;
Clerkin, Lucy;
Schwarcz, Robert

Publication type:

Article

Dynamics of Endogenous Auxin and Its Role in Somatic Embryogenesis Induction and Progression in Cork Oak.

Published in:

Plants (2223-7747), 2023, v. 12, n. 7, p. 1542, doi. 10.3390/plants12071542

By:

Carneros, Elena;
Sánchez-Muñoz, Jorge;
Pérez-Pérez, Yolanda;
Pintos, Beatriz;
Gómez-Garay, Aránzazu;
Testillano, Pilar S.

Publication type:

Article

Mediating the death of dormant tumor cells.

Published in:

Molecular & Cellular Oncology, 2018, v. 5, n. 4, p. 1, doi. 10.1080/23723556.2018.1458013

By:

Liu, Yuying;
Lv, Jiadi;
Huang, Bo

Publication type:

Article

Indoleamine 2,3‐dioxygenase gene expression and kynurenine to tryptophan ratio correlation with nasopharyngeal carcinoma progression and survival.

Published in:

Immunity, Inflammation & Disease, 2022, v. 10, n. 9, p. 1, doi. 10.1002/iid3.690

By:

Souissi, Sameh;
Ghedira, Randa;
Macherki, Yosra;
Ben‐Haj‐Ayed, Ahlem;
Gabbouj, Sallouha;
Remadi, Yasmine;
Sfar, Imen;
Chadli, Zohra;
Aouam, Karim;
Hassine, Mohsen;
Bouaouina, Noureddine;
Zakhama, Abdelfattah;
Hassen, Elham

Publication type:

Article

Kynurenine inhibits melanogenesis in human melanocyte‐keratinocyte co‐cultures and in a reconstructed 3D skin model.

Published in:

Experimental Dermatology, 2022, v. 31, n. 3, p. 427, doi. 10.1111/exd.14486

By:

Ferreira Branquinho, Maryana Stephany;
Silva, Maysa Braga Barros;
Castilho, Gabriela Ansanelo;
Cavalcante, Jacqueline;
Barros, Silvia Berlanga de Moraes;
Clara, Renan Orsati;
Maria‐Engler, Silvya Stuchi;
Campa, Ana

Publication type:

Article

Causal association between kynurenine and depression investigated using two-sample mendelian randomization.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-52442-4

By:

Zong, Luxin;
Ge, Maohong;
Wang, Jiamiao;
Kuang, Dan;
Wei, Hongkai;
Wang, Zhongbao;
Hu, Zerui;
Zhao, Chaoben;
Jin, Qingmin;
Chen, Minghui;
Wang, Chenghui

Publication type:

Article

LC–MS/MS-based quantification of tryptophan, kynurenine, and kynurenic acid in human placental, fetal membranes, and umbilical cord samples.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-39774-3

By:

Pedraz-Petrozzi, Bruno;
Marszalek-Grabska, Marta;
Kozub, Anna;
Szalaj, Klaudia;
Trzpil, Alicja;
Stachniuk, Anna;
Lamadé, Eva Kathrin;
Gilles, Maria;
Deuschle, Michael;
Turski, Waldemar A.;
Fornal, Emilia

Publication type:

Article

Kynurenine promotes Calcitonin secretion and reduces cortisol in the Japanese flounder Paralichthys olivaceus.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-35222-4

By:

Ikari, Takahiro;
Furusawa, Yukihiro;
Tabuchi, Yoshiaki;
Maruyama, Yusuke;
Hattori, Atsuhiko;
Kitani, Yoichiro;
Toyota, Kenji;
Nagami, Arata;
Hirayama, Jun;
Watanabe, Kazuki;
Shigematsu, Atsushi;
Rafiuddin, Muhammad Ahya;
Ogiso, Shouzo;
Fukushi, Keisuke;
Kuroda, Kohei;
Hatano, Kaito;
Sekiguchi, Toshio;
Kawashima, Ryotaro;
Srivastav, Ajai K.;
Nishiuchi, Takumi

Publication type:

Article

Kynurenine 3-monooxygenase: an influential mediator of neuropathology.

Published in:

Frontiers in Psychiatry, 2015, p. 1, doi. 10.3389/fpsyt.2015.00116

By:

Parrott, Jennifer M.;
O'Connor, Jason C.

Publication type:

Article

Disturbed amino acid metabolism in HIV: association with neuropsychiatric symptoms.

Published in:

Frontiers in Psychiatry, 2015, p. 2

By:

Gostner, Johanna M.;
Becker, Kathrin;
Kurz, Katharina;
Fuchs, Dietmar

Publication type:

Article

Vasorelaxing Action of the Kynurenine Metabolite, Xanthurenic Acid: The Missing Link in Endotoxin-Induced Hypotension?

Published in:

Frontiers in Pharmacology, 2017, v. 8, p. 1, doi. 10.3389/fphar.2017.00214

By:

Fazio, Francesco;
Carrizzo, Albino;
Lionetto, Luana;
Damato, Antonio;
Capocci, Luca;
Ambrosio, Mariateresa;
Battaglia, Giuseppe;
Bruno, Valeria;
Madonna, Michele;
Simmaco, Maurizio;
Nicoletti, Ferdinando;
Vecchione, Carmine

Publication type:

Article

An Expanded Neuroimmunomodulation Axis: sCD83-Indoleamine 2,3-Dioxygenase--Kynurenine Pathway and Updates of Kynurenine Pathway in Neurologic Diseases.

Published in:

Frontiers in Immunology, 2018, p. 1, doi. 10.3389/fimmu.2018.01363

By:

Li Bo;
Tan Guojun;
Guo Li

Publication type:

Article

Frontostriatal circuitry and the tryptophan kynurenine pathway in major psychiatric disorders.

Published in:

Psychopharmacology, 2024, v. 241, n. 1, p. 97, doi. 10.1007/s00213-023-06466-9

By:

Liang, Sugai;
Zhao, Liansheng;
Ni, Peiyan;
Wang, Qiang;
Guo, Wanjun;
Xu, Yan;
Cai, Jia;
Tao, Shiwan;
Li, Xiaojing;
Deng, Wei;
Palaniyappan, Lena;
Li, Tao

Publication type:

Article

Acute administration of ibuprofen increases serum concentration of the neuroprotective kynurenine pathway metabolite, kynurenic acid: a pilot randomized, placebo-controlled, crossover study.

Published in:

Psychopharmacology, 2022, v. 239, n. 12, p. 3919, doi. 10.1007/s00213-022-06263-w

By:

Savitz, Jonathan;
Ford, Bart N.;
Kuplicki, Rayus;
Khalsa, Sahib;
Teague, T. Kent;
Paulus, Martin P.

Publication type:

Article

Plasma metabolomic profiling of a ketamine and placebo crossover trial of major depressive disorder and healthy control subjects.

Published in:

Psychopharmacology, 2018, v. 235, n. 10, p. 3017, doi. 10.1007/s00213-018-4992-7

By:

Moaddel, Ruin;
Shardell, Michelle;
Khadeer, Mohammed;
Lovett, Jacqueline;
Kadriu, Bashkim;
Ravichandran, Sarangan;
Morris, Patrick J.;
Yuan, Peixiong;
Thomas, Craig J.;
Gould, Todd D.;
Ferrucci, Luigi;
Zarate, Carlos A.

Publication type:

Article

Prenatal kynurenine treatment in rats causes schizophrenia-like broad monitoring deficits in adulthood.

Published in:

Psychopharmacology, 2018, v. 235, n. 3, p. 651, doi. 10.1007/s00213-017-4780-9

By:

Hahn, Britta;
Reneski, Carolyn H.;
Pocivavsek, Ana;
Schwarcz, Robert

Publication type:

Article

Kynurenic acid and alcohol and cocaine dependence: novel effects and multiple mechanisms?

Published in:

2017

By:

Badawy, Abdulla

Publication type:

Letter

Reply to: kynurenic acid and alcohol and cocaine dependence: novel effects and multiple mechanisms?

Published in:

2017

By:

Vengeliene, Valentina

Publication type:

Letter

Prenatal kynurenine exposure in rats: age-dependent changes in NMDA receptor expression and conditioned fear responding.

Published in:

Psychopharmacology, 2016, v. 233, n. 21/22, p. 3725, doi. 10.1007/s00213-016-4404-9

By:

Pershing, Michelle;
Phenis, David;
Valentini, Valentina;
Pocivavsek, Ana;
Lindquist, Derick;
Schwarcz, Robert;
Bruno, John

Publication type:

Article

Metabolic shift of the kynurenine pathway impairs alcohol and cocaine seeking and relapse.

Published in:

Psychopharmacology, 2016, v. 233, n. 18, p. 3449, doi. 10.1007/s00213-016-4384-9

By:

Vengeliene, Valentina;
Cannella, Nazzareno;
Takahashi, Tatiane;
Spanagel, Rainer

Publication type:

Article

Acute tryptophan depletion reduces kynurenine levels: implications for treatment of impaired visuospatial memory performance in irritable bowel syndrome.

Published in:

Psychopharmacology, 2015, v. 232, n. 8, p. 1357, doi. 10.1007/s00213-014-3767-z

By:

Kennedy, Paul;
Allen, Andrew;
O'Neill, Ann;
Quigley, Eamonn;
Cryan, John;
Dinan, Timothy;
Clarke, Gerard

Publication type:

Article

Continuous kynurenine administration during the prenatal period, but not during adolescence, causes learning and memory deficits in adult rats.

Published in:

Psychopharmacology, 2014, v. 231, n. 14, p. 2799, doi. 10.1007/s00213-014-3452-2

By:

Pocivavsek, Ana;
Thomas, Marian;
Elmer, Greg;
Bruno, John;
Schwarcz, Robert

Publication type:

Article

Effect of Cadmium on the Peripheral Kynurenine Pathway in Rats.

Published in:

Polish Journal of Environmental Studies, 2005, v. 14, n. 4, p. 501

By:

Pawlak, D.;
Brzóska, M.;
Moniuszko-Jakoniuk, J.;
Stypułkowska, A.;
Zwierz, K.

Publication type:

Article

Can Kynurenine Pathway Tryptophan Metabolites Be Used to Monitor Cadmium Exposure?

Published in:

Polish Journal of Environmental Studies, 2005, v. 14, n. 2, p. 209

By:

Pawlak, D.;
Brzoska, M.;
Zwierz, K.;
Stypulkowska, A.;
Moniuszko-Jakoniuk, J.

Publication type:

Article

A Novel Photocatalytic Conversion of Tryptophan to Kynurenine Using Black Light as a Light Source.

Published in:

Catalysis Letters, 2012, v. 142, n. 3, p. 338, doi. 10.1007/s10562-012-0775-7

By:

Hamdy, Mohamed;
Scott, Elinor;
Carr, Robert;
Sanders, Johan

Publication type:

Article

On the benefits of the tryptophan metabolite 3-hydroxyanthranilic acid in Caenorhabditis elegans and mouse aging.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-43527-1

By:

Dang, Hope;
Castro-Portuguez, Raul;
Espejo, Luis;
Backer, Grant;
Freitas, Samuel;
Spence, Erica;
Meyers, Jeremy;
Shuck, Karissa;
Gardea, Emily A.;
Chang, Leah M.;
Balsa, Jonah;
Thorns, Niall;
Corban, Caroline;
Liu, Teresa;
Bean, Shannon;
Sheehan, Susan;
Korstanje, Ron;
Sutphin, George L.

Publication type:

Article

Commentary: The Effect of Systemic Nitroglycerin Administration on the Kynurenine Pathway in the Rat.

Published in:

Frontiers in Neurology, 2017, p. 1, doi. 10.3389/fneur.2017.00518

By:

Moraes Valençax, Marcelo

Publication type:

Article

Breastfeeding and the gut-brain axis: is there a role for melatonin?

Published in:

Biomolecular Concepts, 2017, v. 8, n. 3/4, p. 185, doi. 10.1515/bmc-2017-0009

By:

Anderson, George;
Vaillancourt, Cathy;
Maes, Michael;
Reiter, Russel J.

Publication type:

Article

Melatonin and Elimination of Kynurenines in Children with Down's Syndrome.

Published in:

Journal of Pediatric Endocrinology & Metabolism, 2010, v. 23, n. 3, p. 277, doi. 10.1515/JPEM.2010.23.3.277

By:

Uberos, J.;
Romero, J.;
Molina-Carballo, A.;
Muñoz-Hoyos, A.

Publication type:

Article

Kynurenine and Tetrahydrobiopterin Pathways Crosstalk in Pain Hypersensitivity.

Published in:

Frontiers in Neuroscience, 2020, v. 14, p. 1, doi. 10.3389/fnins.2020.00620

By:

Staats Pires, Ananda;
Tan, Vanessa X.;
Heng, Benjamin;
Guillemin, Gilles J.;
Latini, Alexandra

Publication type:

Article

The role of inflammation in suicidal behaviour.

Published in:

Acta Psychiatrica Scandinavica, 2015, v. 132, n. 3, p. 192, doi. 10.1111/acps.12458

By:

Brundin, L.;
Erhardt, S.;
Bryleva, E. Y.;
Achtyes, E. D.;
Postolache, T. T.

Publication type:

Article

MM165 - A Small Hybrid Molecule Modulates the Kynurenine Pathway and Attenuates Lipopolysaccharide-Induced Memory Deficits and Inflammation.

Published in:

Neurochemical Research, 2024, v. 49, n. 5, p. 1200, doi. 10.1007/s11064-024-04105-z

By:

Kotańska, Magdalena;
Łanocha, Michał;
Bednarski, Marek;
Marcinkowska, Monika

Publication type:

Article

Increased Hippocampal Afterdischarge Threshold in Ketogenic Diet is Accompanied by Enhanced Kynurenine Pathway Activity.

Published in:

Neurochemical Research, 2022, v. 47, n. 7, p. 2109, doi. 10.1007/s11064-022-03605-0

By:

Osuch, Bartosz;
Kołosowska, Karolina;
Chmielewska, Natalia;
Turzyńska, Danuta;
Sobolewska, Alicja;
Szyndler, Janusz;
Maciejak, Piotr

Publication type:

Article

Kynurenine Metabolism and Alzheimer's Disease: The Potential Targets and Approaches.

Published in:

2022

By:

Sharma, Vivek Kumar;
Singh, Thakur Gurjeet;
Prabhakar, Nirbhay Kumar;
Mannan, Ashi

Publication type:

Literature Review

Young Plasma Induces Antidepressant-Like Effects in Aged Rats Subjected to Chronic Mild Stress by Suppressing Indoleamine 2,3-Dioxygenase Enzyme and Kynurenine Pathway in the Prefrontal Cortex.

Published in:

Neurochemical Research, 2022, v. 47, n. 2, p. 358, doi. 10.1007/s11064-021-03440-9

By:

Ghaffari-Nasab, Arshad;
Badalzadeh, Reza;
Mohaddes, Gisou;
Javani, Gonja;
Ebrahimi-kalan, Abbas;
Alipour, Mohammad Reza

Publication type:

Article

Involvement of Indoleamine-2,3-Dioxygenase and Kynurenine Pathway in Experimental Autoimmune Encephalomyelitis in Mice.

Published in:

Neurochemical Research, 2020, v. 45, n. 12, p. 2959, doi. 10.1007/s11064-020-03144-6

By:

Zarzecki, Micheli Stéfani;
Cattelan Souza, Leandro;
Giacomeli, Renata;
Silva, Marcia Rósula Poetini;
Prigol, Marina;
Boeira, Silvana Peterini;
Jesse, Cristiano Ricardo

Publication type:

Article