Works about KYNURENINE

Results: 936

Synthesis and Transformation of Tricyclic KYNA Derivatives.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6248, doi. 10.3390/ijms26136248

By:

Sárik, Julián Robin;
Szatmári, István;
Lőrinczi, Bálint

Publication type:

Article

On-Line Preconcentration of Selected Kynurenine Pathway Metabolites and Amino Acids in Urine via Pressure-Assisted Electrokinetic Injection in a Mixed Micelle System.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 13, p. 6125, doi. 10.3390/ijms26136125

By:

Pieckowski, Michał;
Olędzka, Ilona;
Bączek, Tomasz;
Kowalski, Piotr

Publication type:

Article

Predictive value of kynurenine pathway metabolites in the severity of patients with obsessive‐compulsive disorder.

Published in:

Psychiatry & Clinical Neurosciences, 2025, v. 79, n. 7, p. 378, doi. 10.1111/pcn.13819

By:

Alp, Hamit Hakan;
Kurhan, Faruk;
Akbay, Halil İbrahim

Publication type:

Article

Towards Automated Testing of Kynurenine for Point-of-Care Metabolomics.

Published in:

Methods & Protocols, 2025, v. 8, n. 3, p. 56, doi. 10.3390/mps8030056

By:

Bhattacharyya, Dipanjan;
LeVatte, Marcia A.;
Wishart, David S.

Publication type:

Article

Nanosensor Detection of an Immunoregulatory Tryptophan Influx/Kynurenine Efflux Cycle.

Published in:

PLoS Biology, 2007, v. 5, n. 10, p. e257, doi. 10.1371/journal.pbio.0050257

By:

Kaper, Thijs;
Looger, Loren L.;
Takanaga, Hitomi;
Platten, Michael;
Steinman, Lawrence;
Frommer, Wolf B.

Publication type:

Article

Urinary l‐kynurenine quantification and selective extraction through a molecularly imprinted solid‐phase extraction device.

Published in:

Journal of Separation Science, 2018, v. 41, n. 16, p. 3204, doi. 10.1002/jssc.201800458

By:

Mergola, Lucia;
Vasapollo, Giuseppe;
Scorrano, Sonia;
Del Sole, Roberta;
Orabona, Ciriana;
Albini, Elisa

Publication type:

Article

Chromatographic analysis of tryptophan metabolites.

Published in:

Journal of Separation Science, 2017, v. 40, n. 15, p. 3020, doi. 10.1002/jssc.201700184

By:

Sadok, Ilona;
Gamian, Andrzej;
Staniszewska, Magdalena Maria

Publication type:

Article

Investigation of the aryl hydrocarbon receptor and the intrinsic tumoral component of the kynurenine pathway of tryptophan metabolism in primary brain tumors.

Published in:

Journal of Neuro-Oncology, 2018, v. 139, n. 2, p. 239, doi. 10.1007/s11060-018-2869-6

By:

Guastella, Anthony R.;
Michelhaugh, Sharon K.;
Klinger, Neil V.;
Fadel, Hassan A.;
Kiousis, Sam;
Ali-Fehmi, Rouba;
Kupsky, William J.;
Juhász, Csaba;
Mittal, Sandeep

Publication type:

Article

Increased tryptophan transport in epileptogenic dysembryoplastic neuroepithelial tumors.

Published in:

Journal of Neuro-Oncology, 2012, v. 107, n. 2, p. 365, doi. 10.1007/s11060-011-0750-y

By:

Alkonyi, Bálint;
Mittal, Sandeep;
Zitron, Ian;
Chugani, Diane;
Kupsky, William;
Muzik, Otto;
Chugani, Harry;
Sood, Sandeep;
Juhász, Csaba

Publication type:

Article

Tryptophan degradation and neopterin levels in treated rheumatoid arthritis patients.

Published in:

Clinical Rheumatology, 2012, v. 31, n. 1, p. 29, doi. 10.1007/s10067-011-1767-5

By:

Ozkan, Yesim;
Mete, Guray;
Sepici-Dincel, Aylin;
Sepici, Vesile;
Simsek, Bolkan

Publication type:

Article

Tryptophan degradation increases with stage in patients with rheumatoid arthritis.

Published in:

Clinical Rheumatology, 2006, v. 25, n. 3, p. 334, doi. 10.1007/s10067-005-0056-6

By:

Schroecksnadel, Katharina;
Winkler, Christiana;
Duftner, Christian;
Wirleitner, Barbara;
Schirmer, Michael;
Fuchs, Dietmar

Publication type:

Article

Tryptophan catabolism via kynurenine production in Streptomyces coelicolor: identification of three genes coding for the enzymes of tryptophan to anthranilate pathway.

Published in:

Applied Microbiology & Biotechnology, 2012, v. 94, n. 3, p. 719, doi. 10.1007/s00253-011-3833-y

By:

Zummo, F.;
Marineo, S.;
Pace, A.;
Civiletti, F.;
Giardina, A.;
Puglia, A.

Publication type:

Article

Correlation of ghrelin and obestatin levels with tryptophan degradation in obese children.

Published in:: Public Health Nutrition, 2012, v. 15, n. 8A, p. 1535, doi. 10.1017/S1368980012001590
Publication type:: Article

Ateroskleroz Gelişim Sürecinde Kinürenin Yolağının Rolü: Geleneksel Derleme.

Published in:

Journal of Literature Pharmacy Sciences, 2024, v. 13, n. 2, p. 117, doi. 10.5336/pharmsci.2024-101603

By:

KARADUMAN, Abdullah Burak;
ILGIN, Sinem

Publication type:

Article

Kynurenine pathway of tryptophan metabolism in patients with familial Mediterranean fever.

Published in:

Modern Rheumatology, 2023, v. 33, n. 2, p. 398, doi. 10.1093/mr/roac016

By:

Tezcan, Dilek;
Onmaz, Duygu Eryavuz;
Sivrikay, Abdullah;
Kazim Körez, Muslu;
Hakbilen, Selda;
Gülcemal, Semral;
Yilmaz, Sema

Publication type:

Article

The Kynurenine Pathway in Attention-Deficit/Hyperactivity Disorder: A Systematic Review and Meta-Analysis of Blood Concentrations of Tryptophan and Its Catabolites.

Published in:

Journal of Clinical Medicine, 2024, v. 13, n. 2, p. 583, doi. 10.3390/jcm13020583

By:

Cavaleri, Daniele;
Crocamo, Cristina;
Morello, Pietro;
Bartoli, Francesco;
Carrà, Giuseppe

Publication type:

Article

Correction: Oweira et al. Kynurenine Is the Main Metabolite of Tryptophan Degradation by Tryptophan 2,3-Dioxygenase in HepaRG Tumor Cells. J. Clin. Med. 2022, 11 , 4794.

Published in:

2023

By:

Oweira, Hani;
Lahdou, Imad;
Mehrle, Stefan;
Khajeh, Elias;
Nikbakhsh, Rajan;
Ghamarnejad, Omid;
Terness, Peter;
Reißfelder, Christoph;
Sadeghi, Mahmoud;
Ramouz, Ali

Publication type:

Correction Notice

Serum Kynurenic Acid and Kynurenine Are Negatively Associated with the Risk of Adult Moyamoya Disease.

Published in:

Journal of Clinical Medicine, 2022, v. 11, n. 23, p. 7069, doi. 10.3390/jcm11237069

By:

Yu, Xiaofan;
Ge, Peicong;
Zhai, Yuanren;
Liu, Wei;
Zhang, Qian;
Ye, Xun;
Liu, Xingju;
Wang, Rong;
Zhang, Yan;
Zhao, Jizong;
Zhang, Dong

Publication type:

Article

Kynurenine Is the Main Metabolite of Tryptophan Degradation by Tryptophan 2,3-Dioxygenase in HepG2 Tumor Cells.

Published in:

Journal of Clinical Medicine, 2022, v. 11, n. 16, p. 4794, doi. 10.3390/jcm11164794

By:

Oweira, Hani;
Lahdou, Imad;
Mehrle, Stefan;
Khajeh, Elias;
Nikbakhsh, Rajan;
Ghamarnejad, Omid;
Terness, Peter;
Reißfelder, Christoph;
Sadeghi, Mahmoud;
Ramouz, Ali

Publication type:

Article

Is Poor Lithium Response in Individuals with Bipolar Disorder Associated with Increased Degradation of Tryptophan along the Kynurenine Pathway? Results of an Exploratory Study.

Published in:

Journal of Clinical Medicine, 2022, v. 11, n. 9, p. 2517, doi. 10.3390/jcm11092517

By:

Fellendorf, Frederike T.;
Manchia, Mirko;
Squassina, Alessio;
Pisanu, Claudia;
Dall'Acqua, Stefano;
Sut, Stefania;
Nasini, Sofia;
Congiu, Donatella;
Reininghaus, Eva Z.;
Garzilli, Mario;
Guiso, Beatrice;
Suprani, Federico;
Paribello, Pasquale;
Pulcinelli, Vittoria;
Iaselli, Maria Novella;
Pinna, Ilaria;
Somaini, Giulia;
Arru, Laura;
Corrias, Carolina;
Pinna, Federica

Publication type:

Article

Crosstalk between Tryptophan Metabolism via Kynurenine Pathway and Carbohydrate Metabolism in the Context of Cardio-Metabolic Risk—Review.

Published in:

Journal of Clinical Medicine, 2021, v. 10, n. 11, p. 2484, doi. 10.3390/jcm10112484

By:

Kiluk, Małgorzata;
Lewkowicz, Janina;
Pawlak, Dariusz;
Tankiewicz-Kwedlo, Anna

Publication type:

Article

Tryptophan Metabolism via the Kynurenine Pathway: Implications for Graft Optimization during Machine Perfusion.

Published in:

Journal of Clinical Medicine, 2020, v. 9, n. 6, p. 1864, doi. 10.3390/jcm9061864

By:

Zhang, Anna;
Carroll, Cailah;
Raigani, Siavash;
Karimian, Negin;
Huang, Viola;
Nagpal, Sonal;
Beijert, Irene;
Porte, Robert J.;
Yarmush, Martin;
Uygun, Korkut;
Yeh, Heidi

Publication type:

Article

Impaired Skeletal Muscle Kynurenine Metabolism in Patients with Chronic Obstructive Pulmonary Disease.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 7, p. 915, doi. 10.3390/jcm8070915

By:

Gosker, Harry R.;
Clarke, Gerard;
de Theije, Chiel C.;
Cryan, John F.;
Schols, Annemie M. W. J.

Publication type:

Article

The possible role of the kynurenine pathway in adolescent depression with melancholic features.

Published in:

Journal of Child Psychology & Psychiatry, 2010, v. 51, n. 8, p. 935, doi. 10.1111/j.1469-7610.2010.02245.x

By:

Gabbay, Vilma;
Klein, Rachel G.;
Katz, Yisrael;
Mendoza, Sandra;
Guttman, Leah E.;
Alonso, Carmen M.;
Babb, James S.;
Hirsch, Glenn S.;
Liebes, Leonard

Publication type:

Article

Comparison of plasma tryptophan-related metabolites in crossbred Piétrain and Duroc pigs.

Published in:

Journal of Animal Science, 2017, v. 95, n. 4, p. 1606, doi. 10.2527/jas2016.1179

By:

Floc'h, N. Le;
Simongiovanni, A.;
Corrent, E.;
Matte, J. J.

Publication type:

Article

Effects of Supplementation with the Standardized Extract of Saffron (affron ®) on the Kynurenine Pathway and Melatonin Synthesis in Rats.

Published in:

Antioxidants, 2023, v. 12, n. 8, p. 1619, doi. 10.3390/antiox12081619

By:

De la Fuente Muñoz, Mario;
Román-Carmena, Marta;
Amor, Sara;
García-Villalón, Ángel Luís;
Espinel, Alberto E.;
González-Hedström, Daniel;
Granado García, Miriam

Publication type:

Article

Evaluation of Tryptophan/Kynurenine Pathway Relevance With Immune System Biomarkers of Low Energy Trauma Hip Fractures in Osteoporotic Patients.

Published in:

Archives of Rheumatology, 2017, v. 32, n. 3, p. 203, doi. 10.5606/ArchRheumatol.2017.6216

By:

DİNÇEL, Ercan;
ÖZKAN, Yeşim;
ŞÜKÜROĞLU, Murat;
ÖZSOY, Hakan;
SEPİCİ DİNÇEL, Aylin

Publication type:

Article

Kynurenic acid and kynurenine aminotransferase are potential biomarkers of early neurological improvement after thrombolytic therapy: A pilot study.

Published in:

Advances in Clinical & Experimental Medicine, 2021, v. 30, n. 12, p. 1225, doi. 10.17219/acem/141646

By:

Annus, Ádám;
Tömösi, Ferenc;
Rárosi, Ferenc;
Fehér, Evelin;
Janáky, Tamás;
Kecskeméti, Gábor;
Toldi, József;
Klivényi, Péter;
Sztriha, László;
Vécsei, László

Publication type:

Article

Monitoring the kynurenine system: Concentrations, ratios or what else?

Published in:

Advances in Clinical & Experimental Medicine, 2021, v. 30, n. 8, p. 775, doi. 10.17219/acem/139572

By:

Masaru Tanaka;
Vécsei, László

Publication type:

Article

Molecular basis of wing coloration in a Batesian mimic butterfly, Papilio polytes.

Published in:

Scientific Reports, 2013, p. 1, doi. 10.1038/srep03184

By:

Hideki Nishikawa;
Masatoshi Iga;
Junichi Yamaguchi;
Kazuki Saito;
Hiroshi Kataoka;
Yutaka Suzuki;
Sumio Sugano;
Haruhiko Fujiwara

Publication type:

Article

The kynurenine and serotonin pathway, neopterin and biopterin in depressed children and adolescents: an impact of omega-3 fatty acids, and association with markers related to depressive disorder. A randomized, blinded, prospective study.

Published in:

Frontiers in Psychiatry, 2024, p. 1, doi. 10.3389/fpsyt.2024.1347178

By:

Ilavská, Lucia;
Morvová Jr., Marcela;
Paduchová, Zuzana;
Muchová, Jana;
Garaiova, Iveta;
ková, Zdenka Dŭrač;
Trebatická, Libuša Šikurová Jana;
Trebatická, Jana

Publication type:

Article

Vasorelaxing Action of the Kynurenine Metabolite, Xanthurenic Acid: The Missing Link in Endotoxin-Induced Hypotension?

Published in:

Frontiers in Pharmacology, 2017, v. 8, p. 1, doi. 10.3389/fphar.2017.00214

By:

Fazio, Francesco;
Carrizzo, Albino;
Lionetto, Luana;
Damato, Antonio;
Capocci, Luca;
Ambrosio, Mariateresa;
Battaglia, Giuseppe;
Bruno, Valeria;
Madonna, Michele;
Simmaco, Maurizio;
Nicoletti, Ferdinando;
Vecchione, Carmine

Publication type:

Article

A systematic review and meta-analysis of the kynurenine pathway of tryptophan metabolism in rheumatic diseases.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1257159

By:

Mangoni, Arduino A.;
Zinellu, Angelo

Publication type:

Article

The kynurenine pathway in HIV, frailty and inflammaging.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1244622

By:

Sultana, Shabiha;
Elengickal, Anthony;
Bensreti, Husam;
de Chantemèle, Eric Belin;
McGee-Lawrence, Meghan E.;
Hamrick, Mark W.

Publication type:

Article

Corrigendum: Untargeted metabolomics identified kynurenine as a predictive prognostic biomarker in acute myocardial infarction.

Published in:: Frontiers in Immunology, 2023, v. 14, p. 01, doi. 10.3389/fimmu.2023.1163419
Publication type:: Article

Retraction Note: Kynurenine promotes neonatal heart regeneration by stimulating cardiomyocyte proliferation and cardiac angiogenesis.

Published in:

2025

By:

Zhang, Donghong;
Ning, Jinfeng;
Ramprasath, Tharmarajan;
Yu, Changjiang;
Zheng, Xiaoxu;
Song, Ping;
Xie, Zhonglin;
Zou, Ming-Hui

Publication type:

Correction Notice

Disruption of tryptophan metabolism by high-fat diet-triggered maternal immune activation promotes social behavioral deficits in male mice.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-57414-4

By:

Sun, Penghao;
Wang, Mengli;
Chai, Xuejun;
Liu, Yong-Xin;
Li, Luqi;
Zheng, Wei;
Chen, Shulin;
Zhu, Xiaoyan;
Zhao, Shanting

Publication type:

Article

Mechanistic conformational and substrate selectivity profiles emerging in the evolution of enzymes via parallel trajectories.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-51133-y

By:

Karamitros, Christos S.;
Murray, Kyle;
Kumada, Yoichi;
Johnson, Kenneth A.;
D'Arcy, Sheena;
Georgiou, George

Publication type:

Article

Harnessing intestinal tryptophan catabolism to relieve atherosclerosis in mice.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-50807-x

By:

Chajadine, Mouna;
Laurans, Ludivine;
Radecke, Tobias;
Mouttoulingam, Nirmala;
Al-Rifai, Rida;
Bacquer, Emilie;
Delaroque, Clara;
Rytter, Héloïse;
Bredon, Marius;
Knosp, Camille;
Vilar, José;
Fontaine, Coralie;
Suffee, Nadine;
Vandestienne, Marie;
Esposito, Bruno;
Dairou, Julien;
Launay, Jean Marie;
Callebert, Jacques;
Tedgui, Alain;
Ait-Oufella, Hafid

Publication type:

Article

The NRF2‑PGC‑1β pathway activates kynurenine aminotransferase 4 via attenuation of an E3 ubiquitin ligase, synoviolin, in a cecal ligation/perforation‑induced septic mouse model.

Published in:

Molecular Medicine Reports, 2018, v. 18, n. 2, p. 2467, doi. 10.3892/mmr.2018.9175

By:

Ishida, Yusuke;
Fujita, Hidetoshi;
Aratani, Satoko;
Chijiiwa, Miyuki;
Taniguchi, Noboru;
Yokota, Maho;
Ogihara, Yukihiko;
Uoshima, Naomi;
Nagashima, Fumiaki;
Uchino, Hiroyuki;
Nakajima, Toshihiro

Publication type:

Article

Serum concentration ofL-kynurenine predicts the clinical outcome of patients with diffuse large B-cell lymphoma treated with R-CHOP.

Published in:

European Journal of Haematology, 2010, v. 84, n. 4, p. 304, doi. 10.1111/j.1600-0609.2009.01393.x

By:

Yoshikawa, Takeshi;
Hara, Takeshi;
Tsurumi, Hisashi;
Goto, Naoe;
Hoshi, Masato;
Kitagawa, Junichi;
Kanemura, Nobuhiro;
Kasahara, Senji;
Ito, Hiroyasu;
Takemura, Masao;
Saito, Kuniaki;
Seishima, Mitsuru;
Takami, Tsuyoshi;
Moriwaki, Hisataka

Publication type:

Article

Indoleamine 2, 3-dioxygenase is responsible for low stress tolerance after intracerebral hemorrhage.

Published in:

PLoS ONE, 2023, v. 18, n. 2, p. 1, doi. 10.1371/journal.pone.0273037

By:

Ohnishi, Masatoshi;
Akagi, Marina;
Kotsuki, Mako;
Yonemura, Seishi;
Aokawa, Hikari;
Yamashita-Ibara, Maki;
Yokofujita, Osamu;
Maehara, Shoji;
Hata, Toshiyuki;
Inoue, Atsuko

Publication type:

Article

Half-life of Glycated Tryptophan in the Plasma of Chickens.

Published in:

Journal of Poultry Science, 2018, v. 55, n. 2, p. 117, doi. 10.2141/jpsa.0170158

By:

Ryosuke Makino;
Kazumi Kita

Publication type:

Article

Efficient tryptophan-catabolizing activity is consistently conserved through evolution of TDO enzymes, but not IDO enzymes.

Published in:

Journal of Experimental Zoology Part B: Molecular & Developmental Evolution, 2015, v. 324, n. 2, p. 128, doi. 10.1002/jez.b.22608

By:

Yuasa, Hajime J.;
Ball, Helen J.

Publication type:

Article

Disrupted Tryptophan Metabolism Induced Cognitive Impairment in a Mouse Model of Sepsis-associated Encephalopathy.

Published in:

Inflammation, 2016, v. 39, n. 2, p. 550, doi. 10.1007/s10753-015-0279-x

By:

Gao, Rong;
Kan, Ming-qiang;
Wang, Shi-gang;
Yang, Run-hua;
Zhang, Shao-gang

Publication type:

Article

Bone Marrow Mesenchymal Stem Cells Alleviate Extracellular Kynurenine Levels, as Detected by High-Performance Liquid Chromatography.

Published in:

Inflammation, 2015, v. 38, n. 4, p. 1450, doi. 10.1007/s10753-015-0119-z

By:

Wang, Yuanyuan;
Zhao, Jing;
Tan, Lifei;
Huang, Yueyue;
Li, Dequan;
Quan, Shichao;
Li, Min;
Pan, Jingye

Publication type:

Article

Electroacupuncture attenuates LPS-induced depression-like behavior through kynurenine pathway.

Published in:

Frontiers in Behavioral Neuroscience, 2023, v. 16, p. 1, doi. 10.3389/fnbeh.2022.1052032

By:

Xingying Wu;
Rong Hu;
Shuo Jiang;
Zhong Di;
Yi Chen;
Mengting Shi;
Bowen Chen;
Kelin He;
Kecheng Qian;
Qin Guo;
Ruijie Ma

Publication type:

Article

Kynurenine, Tetrahydrobiopterin, and Cytokine Inflammatory Biomarkers in Individuals Affected by Diabetic Neuropathic Pain.

Published in:

Frontiers in Neuroscience, 2020, v. 14, p. N.PAG, doi. 10.3389/fnins.2020.00890

By:

Staats Pires, Ananda;
Heng, Benjamin;
Tan, Vanessa X.;
Latini, Alexandra;
Russo, Marc A.;
Santarelli, Danielle M.;
Bailey, Dominic;
Wynne, Katie;
O'Brien, Jayden A.;
Guillemin, Gilles J.;
Austin, Paul J.

Publication type:

Article

Kynurenine and Tetrahydrobiopterin Pathways Crosstalk in Pain Hypersensitivity.

Published in:

Frontiers in Neuroscience, 2020, v. 14, p. 1, doi. 10.3389/fnins.2020.00620

By:

Staats Pires, Ananda;
Tan, Vanessa X.;
Heng, Benjamin;
Guillemin, Gilles J.;
Latini, Alexandra

Publication type:

Article

The role of inflammation in suicidal behaviour.

Published in:

Acta Psychiatrica Scandinavica, 2015, v. 132, n. 3, p. 192, doi. 10.1111/acps.12458

By:

Brundin, L.;
Erhardt, S.;
Bryleva, E. Y.;
Achtyes, E. D.;
Postolache, T. T.

Publication type:

Article