Works about KINASE inhibitors

Results: 3305

Canadian Consensus Guidelines for the Management of Atopic Dermatitis with Topical Therapies.

Published in:

Dermatology & Therapy, 2025, v. 15, n. 6, p. 1467, doi. 10.1007/s13555-025-01386-2

By:

Gooderham, Melinda J.;
Hong, H. Chih-ho;
Lynde, Charles;
Papp, Kim A.;
Yeung, Jensen;
Lui, Harvey;
Miller-Monthrope, Yvette;
Ringuet, Julien;
Turchin, Irina;
Prajapati, Vimal H.

Publication type:

Article

New Kinase Inhibitors That Are Selectively Cytotoxic for Tumor Cells.

Published in:

Doklady Biochemistry & Biophysics, 2025, v. 521, n. 1, p. 239, doi. 10.1134/S1607672924601446

By:

Skvortsov, D. A.;
Zhirkina, I. V.;
Ipatova, D. A.;
Pisarev, A. R.;
Malyshev, A. S.;
Ivanenkov, Y. A.;
Kartsev, V. G.;
Dontsova, O. A.

Publication type:

Article

Refractory pediatric actinic prurigo successfully treated with upadacitinib: A case report.

Published in:

2025

By:

Morissette, Florence;
Coulombe, Jérome

Publication type:

Case Study

Cardiovascular safety of Janus kinase inhibitors: A pharmacovigilance study from 2012–2023.

Published in:

PLoS ONE, 2025, v. 20, n. 5, p. 1, doi. 10.1371/journal.pone.0322849

By:

Zhong, Xiaoyan;
Luo, Jianchun;
Huang, Yuexi;
Wang, Shurong;
Huang, Yilan

Publication type:

Article

A Case of Severe Generalized Granuloma Annulare Responding Well to Tofacitinib.

Published in:

2025

By:

Al-Zahawi, Saman;
Ghandi, Narges;
Azhari, Vahidesadat;
Balighi, Kamran;
Dobrev, Hristo

Publication type:

Case Study

Validation of ion mobility spectrometry ‐ mass spectrometry as a screening tool to identify type II kinase inhibitors of FGFR1 kinase.

Published in:

Rapid Communications in Mass Spectrometry: RCM, 2025, v. 39, p. 1, doi. 10.1002/rcm.9130

By:

Beeston, Helen S.;
Klein, Tobias;
Norman, Richard A.;
Tucker, Julie A.;
Anderson, Malcolm;
Ashcroft, Alison E.;
Holdgate, Geoffrey A.

Publication type:

Article

Pilot study of topical ruxolitinib demonstrates efficacy and blunting of heterogeneous inflammatory processes in mild hidradenitis suppurativa.

Published in:

British Journal of Dermatology, 2025, v. 192, n. 5, p. 845, doi. 10.1093/bjd/ljae495

By:

Schell, Stephanie L;
Sennett, Mackenzie L;
Feehan, Robert P;
Wallace, Tierney E;
Meiszberg, Elizabeth C;
Longenecker, Amy L;
Helm, Matthew F;
Kirby, Joslyn S;
Nelson, Amanda M

Publication type:

Article

The emerging role of Bruton's tyrosine kinase inhibition in urticaria management.

Published in:

Expert Opinion on Drug Safety, 2025, v. 24, n. 5, p. 507, doi. 10.1080/14740338.2025.2460453

By:

Lauletta, Giuseppe;
Potestio, Luca;
Patruno, Cataldo;
Cantelli, Mariateresa;
Napolitano, Maddalena

Publication type:

Article

Editorial Note: Development of New Mouse Lung Tumor Models Expressing EGFR T790M Mutants Associated with Clinical Resistance to Kinase Inhibitors.

Published in:: PLoS ONE, 2025, v. 20, n. 5, p. 1, doi. 10.1371/journal.pone.0323763
Publication type:: Article

Monocytic meningitis complicating histiocytosis and response to MEK-inhibitor: a case series.

Published in:

Annals of Hematology, 2025, v. 104, n. 4, p. 2551, doi. 10.1007/s00277-025-06317-x

By:

Abrassart, Tom;
Idbaih, Ahmed;
Roos-Weil, Damien;
Galanaud, Damien;
Cohen-Aubart, Fleur;
Emile, Jean-François;
Boncoeur, Pierre;
Amoura, Zahir;
Seilhean, Danielle;
Haroche, Julien;
Papo, Matthias

Publication type:

Article

A case series on tofacitinib-induced weight gain.

Published in:

Indian Journal of Pharmacology, 2023, v. 55, n. 4, p. 263, doi. 10.4103/ijp.ijp_158_23

By:

Shah, Kanisha;
Shukla, Dhaiwat;
Patel, Manish;
Malhotra, Supriya

Publication type:

Article

Can emapalumab be life saving for refractory, recurrent, and progressive cytokine storm caused by COVID-19, which is resistant to anakinra, tocilizumab, and Janus kinase inhibitors.

Published in:

Indian Journal of Pharmacology, 2021, v. 53, n. 3, p. 226, doi. 10.4103/ijp.IJP_615_20

By:

Cure, Erkan;
Kucuk, Adem;
Cure, Medine

Publication type:

Article

Sorafenib-induced hand-foot syndrome in a patient of renal cell carcinoma.

Published in:

Indian Journal of Pharmacology, 2014, v. 46, n. 3, p. 334, doi. 10.4103/0253-7613.132189

By:

Amrita Sil;
Das, Nilay Kanti

Publication type:

Article

Convergence and Extrusion Are Required for Normal Fusion of the Mammalian Secondary Palate.

Published in:

PLoS Biology, 2015, v. 13, n. 4, p. 1, doi. 10.1371/journal.pbio.1002122

By:

Kim, Seungil;
Lewis, Ace E.;
Singh, Vivek;
Ma, Xuefei;
Adelstein, Robert;
Bush, Jeffrey O.

Publication type:

Article

A Meiosis-Specific Form of the APC/C Promotes the Oocyte-to-Embryo Transition by Decreasing Levels of the Polo Kinase Inhibitor Matrimony.

Published in:

PLoS Biology, 2013, v. 11, n. 9, p. 1, doi. 10.1371/journal.pbio.1001648

By:

Whitfield, Zachary J.;
Chisholm, Jennifer;
Hawley, R. Scott;
Orr-Weaver, Terry L.

Publication type:

Article

Learning long- and short-term dependencies for improving drug-target binding affinity prediction using transformer and edge contraction pooling.

Published in:

Journal of Bioinformatics & Computational Biology, 2024, v. 22, n. 1, p. 1, doi. 10.1142/S0219720023500300

By:

Gao, Min;
Jiang, Shaohua;
Ding, Weibin;
Xu, Ting;
Lyu, Zhijian

Publication type:

Article

Physicochemical and Biological Evaluation of gem‐Difluorinated Saturated Oxygen Heterocycles as Bioisosteres for Drug Discovery.

Published in:

Chemistry - A European Journal, 2025, v. 31, n. 10, p. 1, doi. 10.1002/chem.202404390

By:

Melnykov, Kostiantyn P.;
Liashuk, Oleksandr S.;
Holovach, Serhii;
Shatnia, Valeriia;
Horbenko, Artur;
Lesyk, Dmytro;
Melnyk, Varvara;
Skrypnik, Daniil;
Beshtynarska, Anna;
Borysko, Petro;
Viniichuk, Oleksandr;
Grygorenko, Oleksandr O.

Publication type:

Article

A Phosphoramidate Prodrug Platform: One‐Pot Amine Functionalization of Kinase Inhibitors with Oligoethylene Glycol for Improved Water‐Solubility.

Published in:

Chemistry - A European Journal, 2024, v. 30, n. 49, p. 1, doi. 10.1002/chem.202401781

By:

Spiewok, Sarah;
Lamla, Markus;
Schaefer, Maximilian;
Kuehne, Alexander J. C.

Publication type:

Article

Cover Feature: Optimization of the Lead Compound NVP‐BHG712 as a Colorectal Cancer Inhibitor (Chem. Eur. J. 23/2023).

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 23, p. 1, doi. 10.1002/chem.202300918

By:

Tröster, Alix;
DiPrima, Michael;
Jores, Nathalie;
Kudlinzki, Denis;
Sreeramulu, Sridhar;
Gande, Santosh L.;
Linhard, Verena;
Ludig, Damian;
Schug, Alexander;
Saxena, Krishna;
Reinecke, Maria;
Heinzlmeir, Stephanie;
Leisegang, Matthias S.;
Wollenhaupt, Jan;
Lennartz, Frank;
Weiss, Manfred S.;
Kuster, Bernhard;
Tosato, Giovanna;
Schwalbe, Harald

Publication type:

Article

3D Single-Molecule Imaging of Transmembrane Signaling by Targeting Nanodiamonds.

Published in:

Advanced Functional Materials, 2016, v. 26, n. 3, p. 365, doi. 10.1002/adfm.201502883

By:

Liu, Wenliang;
Yu, Fenglei;
Yang, Jianbo;
Xiang, Bo;
Xiao, Peng;
Wang, Li

Publication type:

Article

Structural basis for RKIP binding with its substrate Raf1 kinase.

Published in:

Biotechnology Letters, 2014, v. 36, n. 9, p. 1869, doi. 10.1007/s10529-014-1558-6

By:

Wu, Zhihua;
Fu, Cuiping;
Shi, Lina;
Ruan, Lu;
Lin, Donghai;
Guo, Chenyun

Publication type:

Article

Fasudil improves short-term echocardiographic parameters of diastolic function in patients with type 2 diabetes with preserved left ventricular ejection fraction: a pilot study.

Published in:

Heart & Vessels, 2015, v. 30, n. 1, p. 89, doi. 10.1007/s00380-013-0458-3

By:

Guo, Rong;
Su, Yang;
Yan, Jing;
Sun, Hui;
Wu, Jiakang;
Liu, Weijing;
Xu, Yawei

Publication type:

Article

Pre-transplant utilization of sorafenib is not associated with increased complications after liver transplantation.

Published in:

Transplant International, 2013, v. 26, n. 7, p. 734, doi. 10.1111/tri.12117

By:

Frenette, Catherine T.;
Boktour, Maha;
Burroughs, Sherilyn G.;
Kaseb, Ahmed;
Aloia, Thomas A.;
Galati, Joseph;
Gaber, Ahmed O.;
Monsour, Howard;
Ghobrial, Rafik M.

Publication type:

Article

Preface.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 67, n. 1, p. 1, doi. 10.1007/s00280-010-1511-x

By:

Patel, Shreyaskumar

Publication type:

Article

Identification and screening of antimalarial phytochemical reservoir from northeastern Indian plants to develop PfRIO-2 kinase inhibitor.

Published in:

European Food Research & Technology, 2012, v. 234, n. 5, p. 905, doi. 10.1007/s00217-012-1692-0

By:

Nag, Swagata;
Prasad, K.;
Trivedi, Vishal

Publication type:

Article

The Effect of Janus Kinase Inhibitors and Phosphodiesterase-4 Inhibitors on Skin and Plasma Cytokine Levels in Patients with Psoriasis.

Published in:

Bulletin of Experimental Biology & Medicine, 2021, v. 171, n. 2, p. 208, doi. 10.1007/s10517-021-05196-2

By:

Artamonova, O. G.;
Karamova, A. E.;
Nikonorov, A. A.;
Verbenko, D. A.;
Vasileva, E. L.;
Kubanov, A. A.

Publication type:

Article

Multipotent Mesenchymal Stromal Cells in Patients with Chronic Myeloid Leukemia before Discontinuation of Tyrosine Kinase Inhibitors.

Published in:

Bulletin of Experimental Biology & Medicine, 2019, v. 167, n. 4, p. 580, doi. 10.1007/s10517-019-04575-0

By:

Petinati, N. A.;
Petrova, A. N.;
Chelysheva, E. Yu.;
Shukhov, O. A.;
Bykova, A. V.;
Nemchenko, I. S.;
Sats, N. V.;
Turkina, A. G.;
Drize, N. I.

Publication type:

Article

Multipotent Mesenchymal Stromal Cells in Patients with Chronic Myeloid Leukemia before Discontinuation of Tyrosine Kinase Inhibitors.

Published in:

Bulletin of Experimental Biology & Medicine, 2019, v. 166, n. 6, p. 580, doi. 10.1007/s10517-019-04575-0

By:

Petinati, N. A.;
Petrova, A. N.;
Chelysheva, E. Yu.;
Shukhov, O. A.;
Bykova, A. V.;
Nemchenko, I. S.;
Sats, N. V.;
Turkina, A. G.;
Drize, N. I.

Publication type:

Article

Tanshinone IIA attenuates Aβ<sub>25-35</sub>-induced spatial memory impairment via upregulating receptors for activated C kinase1 and inhibiting autophagy in hippocampus.

Published in:

Journal of Pharmacy & Pharmacology, 2017, v. 69, n. 2, p. 191, doi. 10.1111/jphp.12650

By:

Zhu, Jiejun;
Liao, Shiping;
Zhou, Liming;
Wan, Lihong

Publication type:

Article

Upadacitinib therapy as a successful treatment of severe atopic dermatitis in a patient with a previous dupilumab-induced exanthematous drug reaction.

Published in:

2024

By:

Kucharczyk, Monika;
Cudzik-Dziurzyńska, Joanna;
Błaszczyk, Aleksandra;
Lewitowicz, Piotr;
Kręcisz, Beata

Publication type:

Case Study

A target map of clinical combination therapies in oncology: an analysis of clinicaltrials.gov.

Published in:

Discover Oncology, 2023, v. 14, n. 1, p. 1, doi. 10.1007/s12672-023-00758-4

By:

Yang, Jing;
Kang, Heming;
Lyu, Liyang;
Xiong, Wei;
Hu, Yuanjia

Publication type:

Article

HER3 activation contributes toward the emergence of ALK inhibitor-tolerant cells in ALK-rearranged lung cancer with mesenchymal features.

Published in:

NPJ Precision Oncology, 2022, v. 6, n. 1, p. 1, doi. 10.1038/s41698-021-00250-8

By:

Tanimura, Keiko;
Yamada, Tadaaki;
Okada, Koutaroh;
Nakai, Kunihiro;
Horinaka, Mano;
Katayama, Yuki;
Morimoto, Kenji;
Ogura, Yuri;
Takeda, Takayuki;
Shiotsu, Shinsuke;
Ichikawa, Kosuke;
Watanabe, Satoshi;
Morimoto, Yoshie;
Iwasaku, Masahiro;
Kaneko, Yoshiko;
Uchino, Junji;
Taniguchi, Hirokazu;
Yoneda, Kazue;
Matoba, Satoaki;
Sakai, Toshiyuki

Publication type:

Article

HER3 activation contributes toward the emergence of ALK inhibitor-tolerant cells in ALK-rearranged lung cancer with mesenchymal features.

Published in:

NPJ Precision Oncology, 2022, v. 6, n. 1, p. 1, doi. 10.1038/s41698-021-00250-8

By:

Tanimura, Keiko;
Yamada, Tadaaki;
Okada, Koutaroh;
Nakai, Kunihiro;
Horinaka, Mano;
Katayama, Yuki;
Morimoto, Kenji;
Ogura, Yuri;
Takeda, Takayuki;
Shiotsu, Shinsuke;
Ichikawa, Kosuke;
Watanabe, Satoshi;
Morimoto, Yoshie;
Iwasaku, Masahiro;
Kaneko, Yoshiko;
Uchino, Junji;
Taniguchi, Hirokazu;
Yoneda, Kazue;
Matoba, Satoaki;
Sakai, Toshiyuki

Publication type:

Article

Acquired JAK2 mutations confer resistance to JAK inhibitors in cell models of acute lymphoblastic leukemia.

Published in:

NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00215-x

By:

Downes, Charlotte E. J.;
McClure, Barbara J.;
Bruning, John B.;
Page, Elyse;
Breen, James;
Rehn, Jacqueline;
Yeung, David T.;
White, Deborah L.

Publication type:

Article

Chondrogenic medium in combination with a c-Jun N-terminal kinase inhibitor mediates engineered cartilage regeneration by regulating matrix metabolism and cell proliferation.

Published in:

Regenerative Biomaterials, 2023, v. 10, p. 1, doi. 10.1093/rb/rbad079

By:

Zhang, Peiling;
Wang, Qianyi;
Chen, Jie;
Ci, Zheng;
Zhang, Wei;
Liu, Yu;
Wang, Xiaoyun;
Zhou, Guangdong

Publication type:

Article

Anlotinib for Metastatic Progressed Pheochromocytoma and Paraganglioma: A Retrospective Study of Real-World Data.

Published in:

Journal of the Endocrine Society, 2024, v. 8, n. 6, p. 1, doi. 10.1210/jendso/bvae061

By:

Tian, Rui;
Yao, Xiaochen;
Song, Jieping;
Wang, Jun;
Fu, Jingjing;
Shi, Liang;
Yu, Fei;
Zhang, Pengjun;
Zhang, Chuan;
Ni, Yudan;
Wang, Feng

Publication type:

Article

Derazantinib alone and with atezolizumab in metastatic urothelial carcinoma with activating FGFR aberrations.

Published in:

JNCI Cancer Spectrum, 2024, v. 8, n. 3, p. 1, doi. 10.1093/jncics/pkae030

By:

Necchi, Andrea;
Ramlau, Rodryg;
González, Alejandro Falcón;
Chaudhry, Arvind;
Todenhöfer, Tilman;
Tahbaz, Rana;
Fontana, Elisa;
Giannatempo, Patrizia;
Deville, Jean-Laurent;
Pouessel, Damien;
Yoon, Shinkyo;
Powles, Thomas;
Bernat, Mathieu;
Häckl, Manuel;
Marszewska, Michalina;
McKernan, Phil;
Saulay, Mikael;
Scaleia, Federica;
Engelhardt, Marc;
Loriot, Yohann

Publication type:

Article

A phase I/II study of nintedanib and capecitabine for refractory metastatic colorectal cancer.

Published in:

JNCI Cancer Spectrum, 2024, v. 8, n. 3, p. 1, doi. 10.1093/jncics/pkae017

By:

Boland, Patrick M;
Ebos, John M L;
Attwood, Kristopher;
Mastri, Michalis;
Fountzilas, Christos;
Iyer, Renuka V;
Banker, Christopher;
Goey, Andrew K L;
Bies, Robert;
Ma, Wen Wee;
Fakih, Marwan

Publication type:

Article

5-Iodotubercidin sensitizes cells to RIPK1-dependent necroptosis by interfering with NFκB signaling.

Published in:

Cell Death Discovery, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41420-023-01576-x

By:

Chauhan, Chanchal;
Kraemer, Andreas;
Knapp, Stefan;
Windheim, Mark;
Kotlyarov, Alexey;
Menon, Manoj B.;
Gaestel, Matthias

Publication type:

Article

The Relative Efficacy and Safety of Monotherapies for Alopecia Areata: A Network Meta‐Analysis Study.

Published in:

Journal of Cosmetic Dermatology, 2025, v. 24, n. 4, p. 1, doi. 10.1111/jocd.70185

By:

Gupta, Aditya K.;
Bamimore, Mary A.;
Mirmirani, Paradi;
Piguet, Vincent;
Talukder, Mesbah

Publication type:

Article

Relative Impact of Monotherapies for Vitiligo: A Network Meta‐Analysis Study.

Published in:

Journal of Cosmetic Dermatology, 2025, v. 24, n. 3, p. 1, doi. 10.1111/jocd.70078

By:

Gupta, Aditya K.;
Bamimore, Mary A.;
Seneschal, Julien;
Piguet, Vincent;
Talukder, Mesbah

Publication type:

Article

Comparative Efficacy and Safety of Baricitinib Against Traditional Therapies in Severe Alopecia Areata: A Retrospective Cohort Study.

Published in:

Journal of Cosmetic Dermatology, 2025, v. 24, n. 2, p. 1, doi. 10.1111/jocd.16666

By:

Stefanis, Athanasios J.;
Dolezal, Tomas;
Gkalpakiotis, Spyridon;
Arenberger, Petr

Publication type:

Article

The relative efficacy of monotherapy with Janus kinase inhibitors, dupilumab and apremilast in adults with alopecia areata: Network meta‐analyses of clinical trials.

Published in:

Journal of Cosmetic Dermatology, 2023, v. 22, n. 9, p. 2553, doi. 10.1111/jocd.15903

By:

Gupta, Aditya K.;
Wang, Tong;
Bamimore, Mary A.;
Piguet, Vincent;
Tosti, Antonella

Publication type:

Article

The use of Janus kinase inhibitors and narrowband ultraviolet B combination therapy in non‐segmental vitiligo.

Published in:

Journal of Cosmetic Dermatology, 2023, v. 22, n. 3, p. 1105, doi. 10.1111/jocd.15537

By:

Yousefian, Faraz;
Yadlapati, Sujitha;
Browning, John C.

Publication type:

Article

Synthesis and Biological Evaluation of 5,6-Dimethylthieno[2,3-d]Pyrimidin-4(3H)-One Derivatives as Selective Cyclooxygenase 2 Inhibitors.

Published in:

Indian Journal of Pharmaceutical Education & Research, 2024, v. 58, p. S515, doi. 10.5530/ijper.58.2s.53

By:

Lim Tse Mun;
Jamie Kow Kean Hing;
Deb, Pran Kishore;
Venugopala, Katharigatta Narayanaswamy;
Mailavaram, Raghu Prasad;
Binsaleh, Ammena Yahia;
Rahim Shilbayeh, Sireen Abdul

Publication type:

Article

Pharmacophore based High Throughput Virtual Screening towards the Discovery of Novel BLK (B-lymphocyte kinase)-tyrosine Kinase Inhibitors.

Published in:

Indian Journal of Pharmaceutical Education & Research, 2023, v. 57, p. s174, doi. 10.5530/ijper.57.1s.21

By:

Sumera, Sana;
Srinivasan, Sanjai;
B. V., Harshitha;
Biradar, Sharanagoud;
Patil, Shankarrao

Publication type:

Article

Identification of (1E, 3E)-1, 3-bis [(2-hydroxy-1-naphthyl) methylene] Urea as Mutated MAP Kinase P38 Inhibitor through Reverse Pharmacophore Mapping Approach: Green Synthesis, Characterisation and in silico Docking analysis.

Published in:

Indian Journal of Pharmaceutical Education & Research, 2019, v. 53, n. 2, p. 276, doi. 10.5530/ijper.53.2.36

By:

Rajamma, Devika Bhai;
Iyer, Girija Chamarahalli Ramakrishna;
Madar, Inamul Hasan;
Karunakar, Prashantha

Publication type:

Article

Exploring Novel ALK Inhibitors using Energy Based Pharmacophore Mapping and High-throughput Virtual Screening.

Published in:

Indian Journal of Pharmaceutical Education & Research, 2018, v. 52, n. 4, p. 707, doi. 10.5530/ijper.52.4.82

By:

James, Nivya;
Surana, Raunaq;
Thigale, Isha;
Preethi, B.;
Shanthi, V.;
Ramanathan, K.

Publication type:

Article

RHO-KINASE INHIBITORS - A NEW BROAD-SPECTRUM TREATMENT IN OPHTHALMIC DISEASES. A REVIEW.

Published in:

Farmacia, 2021, v. 69, n. 3, p. 399, doi. 10.31925/farmacia.2021.3.2

By:

IANCU, RALUCA;
PIRVULESCU, RUXANDRA;
ISTRATE, SANZIANA;
CHERECHEANU, ALINA POPA;
IANCU, GEORGE;
BURCEA, MARIAN

Publication type:

Article

Functionalized 2-Amino-4H-1-Benzopyran-4-yl Phosphonate Scaffolds: Synthesis, Anticancer Evaluation and Computational Studies.

Published in:

Polycyclic Aromatic Compounds, 2024, v. 44, n. 10, p. 6787, doi. 10.1080/10406638.2023.2284799

By:

Sudileti, Murali;
Gundluru, Mohan;
Konidala, Kranthi Kumar;
Chintha, Venkataramaiah;
Nagaripati, Saichaithanya;
Nemallapudi, Bakthavatchala Reddy;
Neeraja, Pabbaraju;
Zyryanov, Grigory V.;
Cirandur, Suresh Reddy

Publication type:

Article