Works matching DE "KINASE inhibitors"

Results: 3368

Trametinib as a promising therapy for Darier disease: case report.

Published in:

British Journal of Dermatology, 2025, v. 193, n. 2, p. 339, doi. 10.1093/bjd/ljaf160

By:

Soto-García, Diego;
Dávila-Seijo, Paula;
González-Moure, Carlota;
Pampín, Ana;
Zulaica, Ander;
Allegue, Francisco;
García-Doval, Ignacio

Publication type:

Article

Clinical, morphological and genetic characteristics of patients with concurrent presence of JAK2 V617F and BCR::ABL1.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-11096-6

By:

Naumann, Nicole;
Dangelo, Vito;
Lübke, Johannes;
Bresser, Jakob;
Hagen, Volker;
Dengler, Jolanta;
Metzgeroth, Georgia;
Kreil, Sebastian;
Hockenberger, Tabea;
Hofmann, Wolf-Karsten;
Fabarius, Alice;
Saussele, Susanne;
Cross, Nicholas C. P.;
Reiter, Andreas;
Schwaab, Juliana

Publication type:

Article

Actualités clinicobiologiques dans les néoplasies myéloprolifératives.

Published in:

2025

By:

Lippert, Éric;
Legros, Laurence;
Gagnon, Laura Li;
Harrison, Claire;
Benajiba, Lina;
Pasquier, Hélène;
Luque Paz, Damien

Publication type:

Abstract

Janus kinase inhibitors and their use in non-infectious orbital inflammatory disorders: new treatment possibilities? A case series.

Published in:

Orbit, 2025, v. 44, n. 4, p. 465, doi. 10.1080/01676830.2024.2430356

By:

Vidic Krhlikar, Nina;
Tomsic, Matija;
Jaki Mekjavic, Polona;
Klobucar, Pia;
Bregar, Janez;
Surlan Popovic, Katarina;
Valentincic, Natasa

Publication type:

Article

Concomitant Use of Analgesics and EGFR TKIs in Lung Cancer Patients: Outcomes and Perspectives From a Finnish Retrospective Register–Based Study.

Published in:

Cancer Medicine, 2025, v. 14, n. 13, p. 1, doi. 10.1002/cam4.71040

By:

Puuniemi, Laura S.;
Iivanainen, Sanna M. E.;
Arffman, Martti;
Kaarteenaho, Riitta L.;
Koivunen, Jussi P.

Publication type:

Article

Medicinal Chemistry of Kinase Inhibitors: A Review of Recent Advances.

Published in:

Cuestiones de Fisioterapia, 2025, v. 54, n. 3, p. 292

By:

Shinymol;
Kuumar, Pushpendra;
Singh, Sakshi;
Kashyap, Manoj;
Kumar, Shivam;
Ambhore, Shraddha Sunil;
Asokan, Neethu;
Rani, Rekha

Publication type:

Article

Computational Design, Molecular Docking and Molecular Dynamics Evaluation of Curcumin-Derived C-Src Kinase Inhibitors For Targeted Cancer Therapy.

Published in:

Cuestiones de Fisioterapia, 2025, v. 54, n. 4, p. 5555

By:

S., Vijayalakshmi;
Karki, Subhas S.

Publication type:

Article

Lestaurtinib's antineoplastic activity converges on JAK/STAT signaling to inhibit treatment naïve and therapy resistant forms ovarian cancer.

Published in:

NPJ Precision Oncology, 2025, v. 9, n. 1, p. 1, doi. 10.1038/s41698-025-00947-0

By:

Rodman, Esther P. B.;
Emch, Michael J.;
Hou, Xiaonan;
Bajaj, Archit;
Pearson, Nicole A.;
John, August J.;
Ortiz, Yamillie;
Bass, Adam D.;
Singh, Saloni;
Baldassarre, Gustavo;
Kaufmann, Scott H.;
Weroha, S. John;
Hawse, John R.

Publication type:

Article

A pharmacovigilance study of thromboembolism events associated with vascular endothelial growth factor receptor tyrosine kinase inhibitors based on FAERS database.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-11067-x

By:

Tang, Zongwei;
Song, Haichi;
Pan, Lingyun;
Zhang, Min;
Li, Siyu;
Li, Wenrui;
Chen, Wanyi;
Wang, Xiaoxiao

Publication type:

Article

Major Adverse Cardiovascular Events Related to JAK Inhibitors: A Disproportionality Analysis Using the WHO Global Individual Case Safety Database.

Published in:

Drug Safety, 2025, v. 48, n. 8, p. 943, doi. 10.1007/s40264-025-01535-8

By:

Di Napoli, Raffaella;
Richez, Christophe;
Scavone, Cristina;
Singier, Allison;
Demourgues, Maxime;
Mascolo, Annamaria;
Capuano, Annalisa;
Salvo, Francesco

Publication type:

Article

KinaseFusionDB: an integrative knowledge of kinase fusion proteins in multi-scales Open Access.

Published in:

Briefings in Bioinformatics, 2025, v. 26, n. 3, p. 1, doi. 10.1093/bib/bbaf259

By:

Kumar, Himansu;
Chen, Zikang;
Adegunlehin, Abayomi;
Trowbridge, Loren;
Aguilar, Leonardo;
Kim, Pora

Publication type:

Article

Integrating Graph Convolution and Attention Mechanism for Kinase Inhibition Prediction.

Published in:

Molecules, 2025, v. 30, n. 13, p. 2871, doi. 10.3390/molecules30132871

By:

Zahid, Hamza;
Chong, Kil To;
Tayara, Hilal

Publication type:

Article

Improved prediction of MAPKi response duration in melanoma patients using genomic data and machine learning.

Published in:

NPJ Precision Oncology, 2025, v. 9, n. 1, p. 1, doi. 10.1038/s41698-025-00814-y

By:

Dandou, Sarah;
Amin, Kriti;
D'Hondt, Véronique;
Solassol, Jérôme;
Dereure, Olivier;
Coopman, Peter J.;
Radulescu, Ovidiu;
Fröhlich, Holger;
Larive, Romain M.

Publication type:

Article

FGFR2 residence in primary cilia is necessary for epithelial cell signaling.

Published in:

Journal of Cell Biology, 2025, v. 224, n. 7, p. 1, doi. 10.1083/jcb.202311030

By:

Nita, Alexandru;
Abraham, Sara P.;
Elrefaay, Eman R.;
Fafilek, Bohumil;
Cizkova, Eliska;
Ursachi, Vlad Constantin;
Gudernova, Iva;
Koudelka, Adolf;
Dudeja, Pooja;
Gregor, Tomas;
Feketova, Zuzana;
Rico, Gustavo;
Svozilova, Katerina;
Celiker, Canan;
Czyrek, Aleksandra A.;
Barta, Tomas;
Trantirek, Lukas;
Wiedlocha, Antoni;
Krejci, Pavel;
Bosakova, Michaela

Publication type:

Article

MelanoDB: A dataset of clinical and molecular features of patients with advanced melanoma treated with MAPK inhibitors.

Published in:

Scientific Data, 2025, v. 12, n. 1, p. 1, doi. 10.1038/s41597-025-05291-3

By:

Dandou, Sarah;
Vendrell, Julie A.;
Solassol, Jérôme;
Louveau, Baptiste;
Lebbé, Céleste;
Mourah, Samia;
Rambow, Florian;
Richard, Eric;
Du Manoir, Stanislas;
Mangé, Alain;
Coopman, Peter J.;
Radulescu, Ovidiu;
Larive, Romain M.

Publication type:

Article

Refractory Segmental Hyaline Vasculitis Treated with Janus Kinase Inhibitor Tofacitinib: A Case Report.

Published in:

2025

By:

Zhang, Yue;
Xia, Rushan

Publication type:

Case Study

Targeting WEE1 and asciminib suppresses ABL-tyrosine kinase inhibitor-resistant chronic myeloid leukemia cells.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-03036-7

By:

Okabe, Seiichi;
Moriyama, Mitsuru;
Gotoh, Akihiko;
Akahane, Daigo

Publication type:

Article

Treatment horizons for advanced radioiodine refractory thyroid cancer: recent developments.

Published in:

Pakistan Journal of Nuclear Medicine, 2024, v. 14, n. 2, p. 38, doi. 10.24911/PJNMed.175-1715857171

By:

Ahmad, Warda;
Imran, Muhammad Babar

Publication type:

Article

The ATM Kinase Inhibitor AZD0156 Is a Potent Inhibitor of Plasmodium Phosphatidylinositol 4‐Kinase (PI4Kβ) and Is an Attractive Candidate for Medicinal Chemistry Optimization Against Malaria.

Published in:

Angewandte Chemie, 2025, v. 137, n. 28, p. 1, doi. 10.1002/ange.202425206

By:

Woodland, John G.;
Coertzen, Dina;
Wicht, Kathryn J.;
Hidalgo, Virginia Franco;
Pasaje, Charisse Flerida A.;
Godoy, Luiz C.;
Qahash, Tarrick;
Mmonwa, Mmakwena M.;
Dziwornu, Godwin A.;
Wambua, Lynn;
Harries, Sarah;
Korkor, Constance M.;
Njoroge, Mathew;
Krugmann, Liezl;
Taylor, Dale;
Leshabane, Meta;
Langeveld, Henrico;
Rabie, Tayla;
Reader, Janette;
van der Watt, Mariëtte

Publication type:

Article

A successful combination of upadacitinib and guselkumab in refractory psoriasis and psoriatic arthritis: A case report.

Published in:

2025

By:

Antolini, Sofia;
Scagliosi, Giorgia;
Veliaj, Olta;
Carletto, Antonio;
Fracassi, Elena;
Gisondi, Paolo

Publication type:

Case Study

EGFR mutations in non-small cell lung cancer: Classification, characteristics and resistance to third-generation EGFR-tyrosine kinase inhibitors (Review).

Published in:

Oncology Letters, 2025, v. 30, n. 2, p. N.PAG, doi. 10.3892/ol.2025.15121

By:

Tian, Zhe;
Cen, Lilan;
Wei, Feng;
Dong, Jue;
Huang, Yulan;
Han, Yi;
Wang, Zhibo;
Deng, Junhua;
Jiang, Yujie

Publication type:

Article

LAURA Completes the Osimertinib Treatment Jigsaw Puzzle of EGFR+ NSCLC from Stage IB to IV: Adjuvant Osimertinib Significantly Improves PFS and CNS Progression in Unresectable Stage III EGFR-Mutated NSCLC Compared to Placebo (LAURA, NCT03521154).

Published in:

Lung Cancer: Targets & Therapy, 2025, v. 16, p. 51, doi. 10.2147/LCTT.S520833

By:

Luo, Faustine;
Arter, Zhaohui;
Ou, Sai-Hong Ignatius;
Nagasaka, Misako

Publication type:

Article

Use of JAK Inhibitors in Lichen Planus: An Update.

Published in:

Medicina (1010660X), 2025, v. 61, n. 6, p. 1056, doi. 10.3390/medicina61061056

By:

Didona, Dario;
Caposiena Caro, Raffaele Dante;
Calabrese, Laura;
D'Onghia, Martina;
Galluccio, Giulia;
Di Nicola, Matteo Riccardo;
Rallo, Alessandra;
Paolino, Giovanni

Publication type:

Article

Discovery of triterpenoid derivatives as novel selective CDC2-like kinase 2 inhibitors against knee osteoarthritis.

Published in:

Journal of Chemical Research, 2025, v. 49, n. 3, p. 1, doi. 10.1177/17475198251338527

By:

Zhang, Xiaozhe;
Shi, Kesong;
Zhang, Tao;
Wang, Qingpu

Publication type:

Article

Predicting Favorable Conditions for the Determination of Initial Use of Janus Kinase Inhibitors in Patients with Moderate to Severe Atopic Dermatitis.

Published in:

Journal of Clinical Medicine, 2025, v. 14, n. 12, p. 4312, doi. 10.3390/jcm14124312

By:

Park, Ju Heon;
Oh, Sejin;
Park, Jihye;
Choi, YoungHwan;
Lee, Jong Hee

Publication type:

Article

Bacterial physiology: Hip persisters.

Published in:

Nature Reviews Microbiology, 2015, v. 13, n. 9, p. 526, doi. 10.1038/nrmicro3538

By:

Nunes-Alves, Cláudio

Publication type:

Article

Bacterial virulence: SteC actin rearrangements, step by step.

Published in:

Nature Reviews Microbiology, 2013, v. 11, n. 1, p. 4, doi. 10.1038/nrmicro2936

By:

David, Rachel

Publication type:

Article

Convergence and Extrusion Are Required for Normal Fusion of the Mammalian Secondary Palate.

Published in:

PLoS Biology, 2015, v. 13, n. 4, p. 1, doi. 10.1371/journal.pbio.1002122

By:

Kim, Seungil;
Lewis, Ace E.;
Singh, Vivek;
Ma, Xuefei;
Adelstein, Robert;
Bush, Jeffrey O.

Publication type:

Article

A Meiosis-Specific Form of the APC/C Promotes the Oocyte-to-Embryo Transition by Decreasing Levels of the Polo Kinase Inhibitor Matrimony.

Published in:

PLoS Biology, 2013, v. 11, n. 9, p. 1, doi. 10.1371/journal.pbio.1001648

By:

Whitfield, Zachary J.;
Chisholm, Jennifer;
Hawley, R. Scott;
Orr-Weaver, Terry L.

Publication type:

Article

Expression of pERK and VEGFR-2 in advanced hepatocellular carcinoma and resistance to sorafenib treatment.

Published in:

Liver International, 2015, v. 35, n. 8, p. 2001, doi. 10.1111/liv.12778

By:

Negri, Francesca V.;
Dal Bello, Barbara;
Porta, Camillo;
Campanini, Nicoletta;
Rossi, Sandro;
Tinelli, Carmine;
Poggi, Guido;
Missale, Gabriele;
Fanello, Silvia;
Salvagni, Stefania;
Ardizzoni, Andrea;
Maria, Silini Enrico

Publication type:

Article

Polymeric Micelles Employing Platinum(II) Linker for the Delivery of the Kinase Inhibitor Dactolisib.

Published in:

Particle & Particle Systems Characterization, 2019, v. 36, n. 8, p. N.PAG, doi. 10.1002/ppsc.201900236

By:

Shi, Haili;
Lou, Bo;
van Steenbergen, Mies J.;
Sijbrandi, Niels J.;
Hennink, Wim E.;
Kok, Robbert J.

Publication type:

Article

Identification and characterization of the process-related impurities in fasudil hydrochloride by hyphenated techniques using a quality by design approach.

Published in:

Journal of Separation Science, 2014, v. 37, n. 7, p. 758, doi. 10.1002/jssc.201301271

By:

Song, Min;
Chen, Yue‐Qin;
Lu, Ping‐Bo;
Hang, Tai‐Jun

Publication type:

Article

3D Single-Molecule Imaging of Transmembrane Signaling by Targeting Nanodiamonds.

Published in:

Advanced Functional Materials, 2016, v. 26, n. 3, p. 365, doi. 10.1002/adfm.201502883

By:

Liu, Wenliang;
Yu, Fenglei;
Yang, Jianbo;
Xiang, Bo;
Xiao, Peng;
Wang, Li

Publication type:

Article

Efficacy of Dabrafenib for three children with brainstem BRAF<sup>V600E</sup> positive ganglioglioma.

Published in:

Journal of Neuro-Oncology, 2019, v. 145, n. 1, p. 135, doi. 10.1007/s11060-019-03280-2

By:

Philippe, Laflamme;
Maria, Kondyli;
Tariq, Aljared;
Sofia, Miconiatis;
Christine, Saint-Martin;
Jean-Pierre, Farmer;
Dudley, Roy W.;
Sébastien, Perreault;
Nada, Jabado;
Valérie, Larouche

Publication type:

Article

Rapid progression of intracranial melanoma metastases controlled with combined BRAF/MEK inhibition after discontinuation of therapy: a clinical challenge.

Published in:

Journal of Neuro-Oncology, 2016, v. 129, n. 3, p. 389, doi. 10.1007/s11060-016-2196-8

By:

Cagney, Daniel;
Alexander, Brian;
Hodi, F.;
Buchbinder, Elizabeth;
Ott, Patrick;
Aizer, Ayal

Publication type:

Article

Survival patterns following brain metastases for patients with melanoma in the MAP-kinase inhibitor era.

Published in:

Journal of Neuro-Oncology, 2015, v. 123, n. 1, p. 75, doi. 10.1007/s11060-015-1761-x

By:

Wattson, Daniel;
Sullivan, Ryan;
Niemierko, Andrzej;
Merritt, Ryan;
Lawrence, Donald;
Oh, Kevin;
Flaherty, Keith;
Shih, Helen

Publication type:

Article

Single agent efficacy of the VEGFR kinase inhibitor axitinib in preclinical models of glioblastoma.

Published in:

Journal of Neuro-Oncology, 2015, v. 121, n. 1, p. 91, doi. 10.1007/s11060-014-1612-1

By:

Lu, Lei;
Saha, Dipongkor;
Martuza, Robert;
Rabkin, Samuel;
Wakimoto, Hiroaki

Publication type:

Article

Kinome profiling of cholangiocarcinoma organoids reveals potential druggable targets that hold promise for treatment stratification.

Published in:

Molecular Medicine, 2022, v. 28, n. 1, p. 1, doi. 10.1186/s10020-022-00498-1

By:

Lieshout, Ruby;
Faria, Alessandra V. S.;
Peppelenbosch, Maikel P.;
van der Laan, Luc J. W.;
Verstegen, Monique M. A.;
Fuhler, Gwenny M.

Publication type:

Article

Polo‐like kinase 1 inhibitor NMS‐P937 represses nasopharyngeal carcinoma progression via induction of mitotic abnormalities.

Published in:

Journal of Biochemical & Molecular Toxicology, 2024, v. 38, n. 1, p. 1, doi. 10.1002/jbt.23590

By:

Gao, Jing;
Huang, Weirong;
Zhao, Senxia;
Wang, Rong;
Wang, Zhilin;
Ye, Juanping;
Lin, Lie;
Cai, Weifeng;
Mi, Yanjun

Publication type:

Article

Safety of Janus kinase inhibitors in rheumatoid arthritis: a disproportionality analysis using FAERS database from 2012 to 2022.

Published in:

Clinical Rheumatology, 2025, v. 44, n. 4, p. 1467, doi. 10.1007/s10067-025-07360-9

By:

Mikaeili, Bahar;
Alqahtani, Zuhair A.;
Hincapie, Ana L.;
Guo, Jeff Jianfei

Publication type:

Article

Real-world study comparing the efficacy of Janus kinase inhibitors in patients with difficult-to-treat rheumatoid arthritis.

Published in:

Clinical Rheumatology, 2024, v. 43, n. 11, p. 3285, doi. 10.1007/s10067-024-07117-w

By:

Hayashi, Shinya;
Nakano, Naoki;
Tsubosaka, Masanori;
Kamenaga, Tomoyuki;
Kuroda, Yuichi;
Matsumoto, Tomoyuki;
Yamada, Hirotaka;
Nishimra, Keisuke;
Ueda, Yo;
Saegusa, Jun;
Kuroda, Ryosuke

Publication type:

Article

Prior herpes zoster occurrence and high-dose corticosteroids increase herpes zoster risk in rheumatoid arthritis patients receiving janus kinase inhibitors in a retrospective and observational study.

Published in:

Clinical Rheumatology, 2024, v. 43, n. 8, p. 2503, doi. 10.1007/s10067-024-07041-z

By:

Chen, Po-Ku;
Chang, Shih-Hsin;
Chen, Yi-Ming;
Chen, Hsin-Hua;
Huang, Po-Hao;
Huang, Chien-Chung;
Yeo, Kai-Jieh;
Lan, Joung-Liang;
Chen, Der-Yuan

Publication type:

Article

ToRaRI (Tofacitinib in Rheumatoid Arthritis a Real-Life experience in Italy): Effectiveness, safety profile of tofacitinib and concordance between patient-reported outcomes and physician's global assessment of disease activity in a retrospective study in Central-Italy

Published in:

Clinical Rheumatology, 2024, v. 43, n. 2, p. 657, doi. 10.1007/s10067-023-06836-w

By:

D'Alessandro, Francesco;
Cazzato, Massimiliano;
Laurino, Elenia;
Morganti, Riccardo;
Bardelli, Marco;
Frediani, Bruno;
Buongarzone, Claudia;
Moroncini, Gianluca;
Guiducci, Serena;
Cometi, Laura;
Benucci, Maurizio;
Ligobbi, Francesca;
Marotto, Daniela;
Mosca, Marta

Publication type:

Article

Rheumatoid arthritis with pulmonary accelerated rheumatoid nodules treated by baricitinib: a case-based review.

Published in:

Clinical Rheumatology, 2024, v. 43, n. 2, p. 775, doi. 10.1007/s10067-023-06773-8

By:

Liu, Haijun;
Li, Qianhua;
Long, Kangxia;
Xia, Ouyang;
Ye, Yufeng;
Wang, Hao;
Dai, Lie

Publication type:

Article

Does baricitinib reduce disease activity in patients with systemic lupus erythematosus? A systematic review and meta-analysis of randomized controlled trials.

Published in:

Clinical Rheumatology, 2024, v. 43, n. 2, p. 579, doi. 10.1007/s10067-023-06731-4

By:

Amer, Basma Ehab;
Afifi, Eslam;
Mouffokes, Adel;
Hamad, Abdullah Ashraf;
Amin, Ahmed Mostafa;
Abdelwahab, Omar Ahmed

Publication type:

Article

Potential alleviation of bone mineral density loss with Janus kinase inhibitors in rheumatoid arthritis.

Published in:

Clinical Rheumatology, 2024, v. 43, n. 1, p. 117, doi. 10.1007/s10067-023-06735-0

By:

Chen, Yun-Wen;
Chen, Hsin-Hua;
Huang, Wen-Nan;
Chen, Jun-Peng;
Chen, Yi-Hsing;
Chen, Yi-Ming

Publication type:

Article

Are all JAK inhibitors for the treatment of rheumatoid arthritis equivalent? An adjusted indirect comparison of the efficacy of tofacitinib, baricitinib, upadacitinib, and filgotinib.

Published in:

Clinical Rheumatology, 2023, v. 42, n. 12, p. 3225, doi. 10.1007/s10067-023-06787-2

By:

Vallez-Valero, Lucía;
Gasó-Gago, Ingrid;
Marcos-Fendian, Ángel;
Garrido-Alejos, Gemma;
Riera-Magallón, Adrià;
Plaza Diaz, Adrián;
Martinez-Molina, Cristina;
Mangues-Bafalluy, Maria Antònia;
Corominas, Hèctor

Publication type:

Article

Efficacy and safety of Janus kinase inhibitors in patients with psoriasis and psoriatic arthritis: a systematic review and meta-analysis.

Published in:

Clinical Rheumatology, 2023, v. 42, n. 6, p. 1593, doi. 10.1007/s10067-023-06529-4

By:

Yang, Fan;
Lu, Chaofan;
Wang, Yanhong;
Liu, Huilan;
Leng, Xiaomei;
Zeng, Xiaofeng

Publication type:

Article

Cardiovascular risks associated with Janus kinase inhibitors: peering outside the black box.

Published in:

Clinical Rheumatology, 2023, v. 42, n. 2, p. 621, doi. 10.1007/s10067-022-06415-5

By:

Misra, Durga Prasanna;
Pande, Gaurav;
Agarwal, Vikas

Publication type:

Article

Safety of JAK inhibitor use in patients with rheumatoid arthritis who developed herpes zoster after receiving JAK inhibitors.

Published in:

Clinical Rheumatology, 2022, v. 41, n. 6, p. 1659, doi. 10.1007/s10067-022-06096-0

By:

Choi, Wonho;
Ahn, Soo Min;
Kim, Yong-Gil;
Lee, Chang-Keun;
Yoo, Bin;
Hong, Seokchan

Publication type:

Article