Works matching DE "KARYOPHERINS"

Results: 87

Changes associated with Ebola virus adaptation to novel species.

Published in:

Bioinformatics, 2017, v. 33, n. 13, p. 1911, doi. 10.1093/bioinformatics/btx065

By:

Pappalardo, Morena;
Reddin, Ian G.;
Cantoni, Diego;
Rossman, Jeremy S.;
Michaelis, Martin;
Wass, Mark N.

Publication type:

Article

Analysis of exportins expression unveils their prognostic significance in colon adenocarcinoma: insights from public databases.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-01748-4

By:

Kalia, Punita;
Nair, Rohini Ravindran;
Yadav, Suresh Singh

Publication type:

Article

Karyopherin subunit‑α 2 expression accelerates cell cycle progression by upregulating CCNB2 and CDK1 in hepatocellular carcinoma.

Published in:

Oncology Letters, 2018, v. 15, n. 3, p. 2815, doi. 10.3892/ol.2017.7691

By:

Gao, Chun-Lin;
Wang, Gao-Wei;
Yang, Guan-Qin;
Yang, Hong;
Zhuang, Li

Publication type:

Article

Karyopherin alpha 2 expression is a novel diagnostic and prognostic factor for colorectal cancer.

Published in:

Oncology Letters, 2017, v. 13, n. 3, p. 1194, doi. 10.3892/ol.2017.5579

By:

LEI YU;
GUIYU WANG;
QIAN ZHANG;
LI GAO;
RUI HUANG;
YINGGANG CHEN;
QINGCHAO TANG;
JIN LIU;
CHUNJIA LIU;
HONGWEI WANG;
XISHAN WANG

Publication type:

Article

Nucleocytoplasmic Communication in Healthy and Diseased Plant Tissues.

Published in:

Frontiers in Plant Science, 2021, v. 12, p. 1, doi. 10.3389/fpls.2021.719453

By:

Lüdke, Daniel;
Rohmann, Philipp F. W.;
Wiermer, Marcel

Publication type:

Article

Transportin 1 colocalization with Fused in Sarcoma (FUS) inclusions is not characteristic for amyotrophic lateral sclerosis- FUS confirming disrupted nuclear import of mutant FUS and distinguishing it from frontotemporal lobar degeneration with FUS inclusions

Published in:

Neuropathology & Applied Neurobiology, 2013, v. 39, n. 5, p. 553, doi. 10.1111/j.1365-2990.2012.01300.x

By:

Troakes, C.;
Hortobágyi, T.;
Vance, C.;
Al‐Sarraj, S.;
Rogelj, B.;
Shaw, C. E.

Publication type:

Article

Cloning and Characterization of Importin α in Brassica napus L.

Published in:

Crop Science, 2013, v. 53, n. 6, p. 2538, doi. 10.2135/cropsci2013.03.0174

By:

Daojie Wang;
Cuiling Yang;
Ming Lu;
Fei Huang;
Aiguang Guo;
Chunpeng Song

Publication type:

Article

Exportins can inhibit major mitotic assembly events in vitro: membrane fusion, nuclear pore formation, and spindle assembly.

Published in:

Nucleus (1949-1034), 2020, v. 11, n. 1, p. 178, doi. 10.1080/19491034.2020.1798093

By:

Nord, Matthew S.;
Bernis, Cyril;
Carmona, Sarah;
Garland, Dennis C.;
Travesa, Anna;
Forbes, Douglass J.

Publication type:

Article

How to operate a nuclear pore complex by Kap-centric control.

Published in:

Nucleus (1949-1034), 2015, v. 6, n. 5, p. 366, doi. 10.1080/19491034.2015.1090061

By:

Lim, Roderick Y H;
Huang, Binlu;
Kapinos, Larisa E

Publication type:

Article

The role of KPNβ<sub>1</sub> in neuro-oncology.

Published in:

OncoTargets & Therapy, 2017, v. 10, p. 2067, doi. 10.2147/OTT.S136247

By:

Lilley, Megan;
Farassati, Faris

Publication type:

Article

Karyopherins: potential biological elements involved in the delayed graft function in renal transplant recipients.

Published in:

BMC Medical Genomics, 2014, v. 7, n. 1, p. 1, doi. 10.1186/1755-8794-7-14

By:

Zaza, Gianluigi;
Rascio, Federica;
Pontrelli, Paola;
Granata, Simona;
Stifanelli, Patrizia;
Accetturo, Matteo;
Ancona, Nicola;
Gesualdo, Loreto;
Lupo, Antonio;
Grandaliano, Giuseppe

Publication type:

Article

Upregulated Expression of Karyopherin α2 is Involved in Neuronal Apoptosis Following Intracerebral Hemorrhage in Adult Rats.

Published in:

Cellular & Molecular Neurobiology, 2016, v. 36, n. 5, p. 755, doi. 10.1007/s10571-015-0258-7

By:

Xu, Zhiwei;
Chen, Jianping;
Shi, Jiansheng;
Zhao, Jianmei;
Wang, Jun;
Ji, Yuhong;
Han, Lijian;
Zhu, Liang;
Li, Xiaohong;
Zhang, Dongmei

Publication type:

Article

The Sequence [RRKLPVGRS] Is a Nuclear Localization Signal for Importin 8 Binding (NLS8): A Chemical Biology and Bioinformatics Study.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 6, p. 2814, doi. 10.3390/ijms26062814

By:

Panagiotopoulos, Athanasios A.;
Kalyvianaki, Konstantina;
Angelidaki, Aikaterini;
Dellis, Dimitris;
Panagiotidis, Christos A.;
Kampa, Marilena;
Castanas, Elias

Publication type:

Article

High expression of KPNA2 defines poor prognosis in patients with upper tract urothelial carcinoma treated with radical nephroureterectomy.

Published in:

BMC Cancer, 2015, v. 15, n. 1, p. 1, doi. 10.1186/s12885-015-1369-8

By:

Bentao Shi;
Boxing Su;
Dong Fang;
Yuan Tang;
Gengyan Xiong;
Zhongqiang Guo;
Qun He;
Xinyu Yang;
Wei Zhao;
Yinglu Guo;
Xuesong Li;
Liqun Zhou

Publication type:

Article

The Ebola Virus Interferon Antagonist VP24 Directly Binds STAT1 and Has a Novel, Pyramidal Fold.

Published in:

PLoS Pathogens, 2012, v. 8, n. 2, p. 1, doi. 10.1371/journal.ppat.1002550

By:

Zhang, Adrianna P. P.;
Bornholdt, Zachary A.;
Liu, Tong;
Abelson, Dafna M.;
Lee, David E.;
Sheng Li;
Woods Jr., Virgil L.;
Saphire, Erica Ollmann

Publication type:

Article

Karyopherin α-2 is a reliable marker for identification of patients with high-risk stage II colorectal cancer.

Published in:

Journal of Cancer Research & Clinical Oncology, 2017, v. 143, n. 12, p. 2493, doi. 10.1007/s00432-017-2512-5

By:

Jeong, Dongjun;
Kim, Hyeongjoo;
Ban, Seona;
Oh, Seunghyun;
Ji, Sanghee;
Kim, Doyeon;
Ahn, Tae;
Kim, Han;
Bae, Sang;
Kwon, Hyog;
Im, Jungkyun;
Lee, Moon;
Cho, Hyun;
Kim, Chang-Jin;
Baek, Moo-Jun

Publication type:

Article

Upregulation of nuclear transporter, Kpnβ1, contributes to accelerated cell proliferation- and cell adhesion-mediated drug resistance (CAM-DR) in diffuse large B-cell lymphoma.

Published in:

Journal of Cancer Research & Clinical Oncology, 2016, v. 142, n. 3, p. 561, doi. 10.1007/s00432-015-2057-4

By:

He, Song;
Miao, Xiaobing;
Wu, Yaxun;
Zhu, Xinghua;
Miao, Xianjing;
Yin, Haibing;
He, Yunhua;
Li, Chunsun;
Liu, Yushan;
Lu, Xiaoyun;
Chen, Yali;
Wang, Yuchan;
Xu, Xiaohong

Publication type:

Article

Controlling the Gatekeeper: Therapeutic Targeting of Nuclear Transport.

Published in:

Cells (2073-4409), 2018, v. 7, n. 11, p. 221, doi. 10.3390/cells7110221

By:

Kosyna, Friederike K.;
Depping, Reinhard

Publication type:

Article

Nuclear karyopherin-α2 expression in primary lesions and metastatic lymph nodes was associated with poor prognosis and progression in gastric cancer.

Published in:

Carcinogenesis, 2013, v. 34, n. 10, p. 2314, doi. 10.1093/carcin/bgt214

By:

Altan, Bolag;
Yokobori, Takehiko;
Mochiki, Erito;
Ohno, Tetsuro;
Ogata, Kyoichi;
Ogawa, Atsushi;
Yanai, Mitsuhiro;
Kobayashi, Tsutomu;
Luvsandagva, Baigalimaa;
Asao, Takayuki;
Kuwano, Hiroyuki

Publication type:

Article

CLAVATA3 mediated simultaneous control of transcriptional and post-translational processes provides robustness to the WUSCHEL gradient.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26586-0

By:

Plong, Alexander;
Rodriguez, Kevin;
Alber, Mark;
Chen, Weitao;
Reddy, G. Venugopala

Publication type:

Article

Recapitulation of selective nuclear import and export with a perfectly repeated 12mer GLFG peptide.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-24292-5

By:

Ng, Sheung Chun;
Güttler, Thomas;
Görlich, Dirk

Publication type:

Article

Targeting nuclear transporters in cancer: Diagnostic, prognostic and therapeutic potential.

Published in:

IUBMB Life, 2016, v. 68, n. 4, p. 268, doi. 10.1002/iub.1484

By:

Stelma, Tamara;
Chi, Alicia;
van der Watt, Pauline J.;
Verrico, Annalisa;
Lavia, Patrizia;
Leaner, Virna D.

Publication type:

Article

A multifunctional, multi-pathway intracellular localization signal in Huntingtin.

Published in:

Communicative & Integrative Biology, 2013, v. 6, n. 2, p. e23318-1, doi. 10.4161/cib.23318

By:

Desmond, Carly R.;
Maiuri, Tamara;
Truant, Ray

Publication type:

Article

Nucleocytoplasmic Shuttling of Cytoskeletal Proteins: Molecular Mechanism and Biological Significance.

Published in:

International Journal of Cell Biology, 2012, p. 1, doi. 10.1155/2012/494902

By:

Kumeta, Masahiro;
Yoshimura, Shige H.;
Hejna, James;
Takeyasu, Kunio

Publication type:

Article

The Interaction of FABP with Kapα.

Published in:

PLoS ONE, 2015, v. 10, n. 8, p. 1, doi. 10.1371/journal.pone.0132138

By:

Amber-Vitos, Ortal;
Kucherenko, Nataly;
Nachliel, Esther;
Gutman, Menachem;
Tsfadia, Yossi

Publication type:

Article

BIG3 Inhibits the Estrogen-Dependent Nuclear Translocation of PHB2 via Multiple Karyopherin-Alpha Proteins in Breast Cancer Cells.

Published in:

PLoS ONE, 2015, v. 10, n. 6, p. 1, doi. 10.1371/journal.pone.0127707

By:

Kim, Nam-Hee;
Yoshimaru, Tetsuro;
Chen, Yi-An;
Matsuo, Taisuke;
Komatsu, Masato;
Miyoshi, Yasuo;
Tanaka, Eiji;
Sasa, Mitsunori;
Mizuguchi, Kenji;
Katagiri, Toyomasa

Publication type:

Article

Structure of Importin-α from a Filamentous Fungus in Complex with a Classical Nuclear Localization Signal.

Published in:

PLoS ONE, 2015, v. 10, n. 6, p. 1, doi. 10.1371/journal.pone.0128687

By:

Bernardes, Natalia E.;
Takeda, Agnes A. S.;
Dreyer, Thiago R.;
Freitas, Fernanda Z.;
Bertolini, Maria Célia;
Fontes, Marcos R. M.

Publication type:

Article

ULK2 Ser 1027 Phosphorylation by PKA Regulates Its Nuclear Localization Occurring through Karyopherin Beta 2 Recognition of a PY-NLS Motif.

Published in:

PLoS ONE, 2015, v. 10, n. 6, p. 1, doi. 10.1371/journal.pone.0127784

By:

Shin, Sung Hwa;
Lee, Eun Jeoung;
Chun, Jaesun;
Hyun, Sunghee;
Kang, Sang Sun

Publication type:

Article

Characterization of the Nuclear Import Mechanism of the CCAAT-Regulatory Subunit Php4.

Published in:

PLoS ONE, 2014, v. 9, n. 10, p. 1, doi. 10.1371/journal.pone.0110721

By:

Khan, Md. Gulam Musawwir;
Jacques, Jean-François;
Beaudoin, Jude;
Labbé, Simon

Publication type:

Article

Cytoplasmic Dynamics of the General Nuclear Import Machinery in Apically Growing Syncytial Cells.

Published in:

PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0085076

By:

Etxebeste, Oier;
Villarino, María;
Markina-Iñarrairaegui, Ane;
Araújo-Bazán, Lidia;
Espeso, Eduardo A.

Publication type:

Article

Karyopherin Alpha2 Is Essential for rRNA Transcription and Protein Synthesis in Proliferative Keratinocytes.

Published in:

PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0076416

By:

Umegaki-Arao, Noriko;
Tamai, Katsuto;
Nimura, Keisuke;
Serada, Satoshi;
Naka, Tetsuji;
Nakano, Hajime;
Katayama, Ichiro

Publication type:

Article

Molecular Profiling of Multiple Human Cancers Defines an Inflammatory Cancer-Associated Molecular Pattern and Uncovers KPNA2 as a Uniform Poor Prognostic Cancer Marker.

Published in:

PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0057911

By:

Rachidi, Saleh M.;
Qin, Tingting;
Sun, Shaoli;
Zheng, W. Jim;
Li, Zihai

Publication type:

Article

Overexpression of Kpnβ1 and Kpnα2 Importin Proteins in Cancer Derives from Deregulated E2F Activity.

Published in:

PLoS ONE, 2011, v. 6, n. 11, p. 1, doi. 10.1371/journal.pone.0027723

By:

van der Watt, Pauline J.;
Ngarande, Ellen;
Leaner, Virna D.

Publication type:

Article

Efficient Nuclear Transport of Structurally Disturbed Cargo: Mutations in a Cargo Protein Switch Its Cognate Karyopherin.

Published in:

PLoS ONE, 2011, v. 6, n. 2, p. 1, doi. 10.1371/journal.pone.0016846

By:

Chaves, Susana R.;
Rosenblum, Jonathan S.

Publication type:

Article

Yeast 26S proteasome nuclear import is coupled to nucleus-specific degradation of the karyopherin adaptor protein Sts1.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-52352-5

By:

Breckel, Carolyn Allain;
Johnson, Zane M.;
Hickey, Christopher M.;
Hochstrasser, Mark

Publication type:

Article

Zika virus NS2A protein induces the degradation of KPNA2 (karyopherin subunit alpha 2) via chaperone-mediated autophagy.

Published in:

Autophagy, 2020, v. 16, n. 12, p. 2238, doi. 10.1080/15548627.2020.1823122

By:

He, Jia;
Yang, Liping;
Chang, Peixi;
Yang, Shixing;
Lin, Shaoli;
Tang, Qiyi;
Wang, Xinping;
Zhang, Yan-Jin

Publication type:

Article

Characterization of p92, Karyopherin β, Co-Purified with N-Acetylglucosamine–Bearing Nucleoporins from Rat Liver Nuclear Envelopes1.

Published in:

Journal of Biochemistry, 1996, v. 120, n. 4, p. 716, doi. 10.1093/oxfordjournals.jbchem.a021470

By:

Makifuchi, Shigehito;
Takeuchi, Masaki;
kawahire, shigeru;
Odani, Shoji;
Ichimura, Tohru;
Omata, Saburo;
Horigome, Tsuneyoshi

Publication type:

Article

Karyopherin abnormalities in neurodegenerative proteinopathies.

Published in:

2021

By:

Pasha, Terouz;
Zatorska, Anna;
Sharipov, Daulet;
Rogelj, Boris;
Hortobágyi, Tibor;
Hirth, Frank

Publication type:

journal article

Chikungunya virus capsid protein contains nuclear import and export signals.

Published in:

Virology Journal, 2013, v. 10, n. 1, p. 1, doi. 10.1186/1743-422X-10-269

By:

Thomas, Saijo;
Rai, Jagdish;
John, Lijo;
Schaefer, Stephan;
Pützer, Brigitte M.;
Herchenröder, Ottmar

Publication type:

Article

Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS.

Published in:

Nature Neuroscience, 2015, v. 18, n. 9, p. 1226, doi. 10.1038/nn.4085

By:

Jovičić, Ana;
Mertens, Jerome;
Boeynaems, Steven;
Bogaert, Elke;
Chai, Noori;
Yamada, Shizuka B;
Paul, Joseph W;
Sun, Shuying;
Herdy, Joseph R;
Bieri, Gregor;
Kramer, Nicholas J;
Gage, Fred H;
Van Den Bosch, Ludo;
Robberecht, Wim;
Gitler, Aaron D

Publication type:

Article

Karyopherin Alpha Proteins Regulate Oligodendrocyte Differentiation.

Published in:

PLoS ONE, 2017, v. 12, n. 1, p. 1, doi. 10.1371/journal.pone.0170477

By:

Laitman, Benjamin M.;
Mariani, John N.;
Zhang, Chi;
Sawai, Setsu;
John, Gareth R.

Publication type:

Article

Up-Regulation of KPNB1 Involves in Neuronal Apoptosis Following Intracerebral Hemorrhage in Adult Rats.

Published in:

Neurochemical Research, 2015, v. 40, n. 11, p. 2177, doi. 10.1007/s11064-015-1706-y

By:

Dai, Aihua;
Liu, Xiaorong;
Zhang, Yu;
Han, Lijian;
Zhu, Liang;
Ni, Haidan;
Chen, Rongrong;
Cao, Maohong

Publication type:

Article

Karyopherin Alpha 2 Promotes the Inflammatory Response in Rat Pancreatic Acinar Cells Via Facilitating NF-κB Activation.

Published in:

2016

By:

Cai, Yongxia;
Shen, Yanbo;
Gao, Lili;
Chen, Minmin;
Xiao, Min;
Huang, Zhongwei;
Zhang, Dongmei

Publication type:

journal article

Synthesis and Biological Evaluation of 2-Aminothiazole Derivative Having Anticancer Activity as a KPNB1 Inhibitor.

Published in:

Bulletin of the Korean Chemical Society, 2016, v. 37, n. 11, p. 1743, doi. 10.1002/bkcs.10968

By:

Ha, Siyoung;
Oh, Jiwon;
Jang, Ji Min;
Kim, Dae Kyong;
Ham, Seung Wook

Publication type:

Article

Reactive Oxygen Species-Mediated DJ-1 Monomerization Modulates Intracellular Trafficking Involving Karyopherin β2.

Published in:

Molecular & Cellular Biology, 2014, v. 34, n. 16, p. 3024, doi. 10.1128/MCB.00286-14

By:

Björkblom, Benny;
Maple-Grødem, Jodi;
Puno, Marc Rhyan;
Odell, Mark;
Larsen, Jan Petter;
Møller, Simon Geir

Publication type:

Article

Androgen Induces a Switch from Cytoplasmic Retention to Nuclear Import of the Androgen Receptor.

Published in:

Molecular & Cellular Biology, 2013, v. 33, n. 24, p. 4766, doi. 10.1128/MCB.00647-13

By:

Li Ni;
Llewellyn, Ryan;
Kesler, Cristina T.;
Kelley, Joshua B.;
Spencer, Adam;
Snow, Chelsi J.;
Shank, Leonard;
Paschal, Bryce M.

Publication type:

Article

Rtp1p Is a Karyopherin-Like Protein Required for RNA Polymerase II Biogenesis.

Published in:

Molecular & Cellular Biology, 2013, v. 33, n. 9, p. 1756, doi. 10.1128/MCB.01449-12

By:

Gómez-Navarro, Natalia;
Peiró-Chova, Lorena;
Rodriguez-Navarro, Susana;
Polaina, Julio;
Estruch, Francisco

Publication type:

Article

Karyopherin a2 and chromosome region maintenance protein 1 expression in meningiomas: novel biomarkers for recurrence and malignant progression.

Published in:

Journal of Neuro-Oncology, 2014, v. 118, n. 2, p. 289, doi. 10.1007/s11060-014-1423-4

By:

Gousias, Konstantinos;
Niehusmann, Pitt;
Gielen, Gerrit;
Simon, Matthias

Publication type:

Article

Nuclear karyopherin a2: a novel biomarker for infiltrative astrocytomas.

Published in:

Journal of Neuro-Oncology, 2012, v. 109, n. 3, p. 545, doi. 10.1007/s11060-012-0924-2

By:

Gousias, K.;
Becker, A.;
Simon, M.;
Niehusmann, P.

Publication type:

Article

Mechanism of karyopherin-β2 binding and nuclear import of ALS variants FUS(P525L) and FUS(R495X).

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-83196-y

By:

Gonzalez, Abner;
Mannen, Taro;
Çağatay, Tolga;
Fujiwara, Ayano;
Matsumura, Hiroyoshi;
Niesman, Ashley B.;
Brautigam, Chad A.;
Chook, Yuh Min;
Yoshizawa, Takuya

Publication type:

Article