Works matching DE "KARYOPHERINS"

Results: 87

Yeast 26S proteasome nuclear import is coupled to nucleus-specific degradation of the karyopherin adaptor protein Sts1.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-52352-5

By:

Breckel, Carolyn Allain;
Johnson, Zane M.;
Hickey, Christopher M.;
Hochstrasser, Mark

Publication type:

Article

Exportins can inhibit major mitotic assembly events in vitro: membrane fusion, nuclear pore formation, and spindle assembly.

Published in:

Nucleus (1949-1034), 2020, v. 11, n. 1, p. 178, doi. 10.1080/19491034.2020.1798093

By:

Nord, Matthew S.;
Bernis, Cyril;
Carmona, Sarah;
Garland, Dennis C.;
Travesa, Anna;
Forbes, Douglass J.

Publication type:

Article

How to operate a nuclear pore complex by Kap-centric control.

Published in:

Nucleus (1949-1034), 2015, v. 6, n. 5, p. 366, doi. 10.1080/19491034.2015.1090061

By:

Lim, Roderick Y H;
Huang, Binlu;
Kapinos, Larisa E

Publication type:

Article

Up-Regulation of KPNB1 Involves in Neuronal Apoptosis Following Intracerebral Hemorrhage in Adult Rats.

Published in:

Neurochemical Research, 2015, v. 40, n. 11, p. 2177, doi. 10.1007/s11064-015-1706-y

By:

Dai, Aihua;
Liu, Xiaorong;
Zhang, Yu;
Han, Lijian;
Zhu, Liang;
Ni, Haidan;
Chen, Rongrong;
Cao, Maohong

Publication type:

Article

The Ebola Virus VP24 Protein Prevents hnRNP C1/C2 Binding to Karyopherin &agr;1 and Partially Alters its Nuclear Import.

Published in:

Journal of Infectious Diseases, 2011, v. 204, p. S904, doi. 10.1093/infdis/jir323

By:

Shabman, Reed S.;
Gulcicek, Erol E.;
Stone, Kathryn L.;
Basler, Christopher F.

Publication type:

Article

Characterization of the subcellular localization and nuclear import molecular mechanisms of herpes simplex virus 1 UL2.

Published in:

Biological Chemistry, 2017, v. 398, n. 4, p. 509, doi. 10.1515/hsz-2016-0268

By:

Mingsheng Cai;
Zebin Huang;
Zongmin Liao;
Tao Chen;
Ping Wang;
Si Jiang;
Daixiong Chen;
Tao Peng;
Yun Bian;
Gengde Hong;
Hang Yang;
Zhancheng Zeng;
Xiaowei Li;
Meili Li

Publication type:

Article

Karyopherin a2 and chromosome region maintenance protein 1 expression in meningiomas: novel biomarkers for recurrence and malignant progression.

Published in:

Journal of Neuro-Oncology, 2014, v. 118, n. 2, p. 289, doi. 10.1007/s11060-014-1423-4

By:

Gousias, Konstantinos;
Niehusmann, Pitt;
Gielen, Gerrit;
Simon, Matthias

Publication type:

Article

Nuclear karyopherin a2: a novel biomarker for infiltrative astrocytomas.

Published in:

Journal of Neuro-Oncology, 2012, v. 109, n. 3, p. 545, doi. 10.1007/s11060-012-0924-2

By:

Gousias, K.;
Becker, A.;
Simon, M.;
Niehusmann, P.

Publication type:

Article

Mechanism of karyopherin-β2 binding and nuclear import of ALS variants FUS(P525L) and FUS(R495X).

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-83196-y

By:

Gonzalez, Abner;
Mannen, Taro;
Çağatay, Tolga;
Fujiwara, Ayano;
Matsumura, Hiroyoshi;
Niesman, Ashley B.;
Brautigam, Chad A.;
Chook, Yuh Min;
Yoshizawa, Takuya

Publication type:

Article

Nucleocytoplasmic Communication in Healthy and Diseased Plant Tissues.

Published in:

Frontiers in Plant Science, 2021, v. 12, p. 1, doi. 10.3389/fpls.2021.719453

By:

Lüdke, Daniel;
Rohmann, Philipp F. W.;
Wiermer, Marcel

Publication type:

Article

Nuclear karyopherin-α2 expression in primary lesions and metastatic lymph nodes was associated with poor prognosis and progression in gastric cancer.

Published in:

Carcinogenesis, 2013, v. 34, n. 10, p. 2314, doi. 10.1093/carcin/bgt214

By:

Altan, Bolag;
Yokobori, Takehiko;
Mochiki, Erito;
Ohno, Tetsuro;
Ogata, Kyoichi;
Ogawa, Atsushi;
Yanai, Mitsuhiro;
Kobayashi, Tsutomu;
Luvsandagva, Baigalimaa;
Asao, Takayuki;
Kuwano, Hiroyuki

Publication type:

Article

Pleomorphic adenoma gene 1 mediates the role of Karyopherin alpha 2 and has prognostic significance in hepatocellular carcinoma.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2014, v. 33, n. 1, p. 1, doi. 10.1186/s13046-014-0061-1

By:

Zhe-yuan Hu;
Sheng-xian Yuan;
Yuan Yang;
Wei-ping Zhou;
Hua Jiang

Publication type:

Article

KPNA2 is a nuclear export protein that contributes to aberrant localisation of key proteins and poor prognosis of breast cancer.

Published in:

British Journal of Cancer, 2015, v. 112, n. 12, p. 1929, doi. 10.1038/bjc.2015.165

By:

Alshareeda, A T;
Negm, O H;
Green, A R;
Nolan, C C;
Tighe, P;
Albarakati, N;
Sultana, R;
Madhusudan, S;
Ellis, I O;
Rakha, E A

Publication type:

Article

Synthesis and Biological Evaluation of 2-Aminothiazole Derivative Having Anticancer Activity as a KPNB1 Inhibitor.

Published in:

Bulletin of the Korean Chemical Society, 2016, v. 37, n. 11, p. 1743, doi. 10.1002/bkcs.10968

By:

Ha, Siyoung;
Oh, Jiwon;
Jang, Ji Min;
Kim, Dae Kyong;
Ham, Seung Wook

Publication type:

Article

Transportin 1 colocalization with Fused in Sarcoma (FUS) inclusions is not characteristic for amyotrophic lateral sclerosis- FUS confirming disrupted nuclear import of mutant FUS and distinguishing it from frontotemporal lobar degeneration with FUS inclusions

Published in:

Neuropathology & Applied Neurobiology, 2013, v. 39, n. 5, p. 553, doi. 10.1111/j.1365-2990.2012.01300.x

By:

Troakes, C.;
Hortobágyi, T.;
Vance, C.;
Al‐Sarraj, S.;
Rogelj, B.;
Shaw, C. E.

Publication type:

Article

Targeting nuclear transporters in cancer: Diagnostic, prognostic and therapeutic potential.

Published in:

IUBMB Life, 2016, v. 68, n. 4, p. 268, doi. 10.1002/iub.1484

By:

Stelma, Tamara;
Chi, Alicia;
van der Watt, Pauline J.;
Verrico, Annalisa;
Lavia, Patrizia;
Leaner, Virna D.

Publication type:

Article

XPO1-dependent nuclear export as a target for cancer therapy.

Published in:

Journal of Hematology & Oncology, 2020, v. 13, n. 1, p. 1, doi. 10.1186/s13045-020-00903-4

By:

Azizian, Nancy G.;
Li, Yulin

Publication type:

Article

Karyopherin Alpha Proteins Regulate Oligodendrocyte Differentiation.

Published in:

PLoS ONE, 2017, v. 12, n. 1, p. 1, doi. 10.1371/journal.pone.0170477

By:

Laitman, Benjamin M.;
Mariani, John N.;
Zhang, Chi;
Sawai, Setsu;
John, Gareth R.

Publication type:

Article

Association of overexpressed karyopherin alpha 2 with poor survival and its contribution to interleukin‐1β‐induced matrix metalloproteinase expression in oral cancer.

Published in:

Head & Neck, 2018, v. 40, n. 8, p. 1719, doi. 10.1002/hed.25145

By:

Wang, Chun‐I;
Yu, Chia‐Jung;
Huang, Yenlin;
Yi, Jui‐Shan;
Cheng, Hsing‐Wen;
Kao, Huang‐Kai;
Lao, William Wei‐Kai;
Chang, Kai‐Ping

Publication type:

Article

Importins and Exportins Regulating Allergic Immune Responses.

Published in:

Mediators of Inflammation, 2014, v. 2014, p. 1, doi. 10.1155/2014/476357

By:

Aggarwal, Ankita;
Agrawal, Devendra K.

Publication type:

Article

Karyopherin subunit‑α 2 expression accelerates cell cycle progression by upregulating CCNB2 and CDK1 in hepatocellular carcinoma.

Published in:

Oncology Letters, 2018, v. 15, n. 3, p. 2815, doi. 10.3892/ol.2017.7691

By:

Gao, Chun-Lin;
Wang, Gao-Wei;
Yang, Guan-Qin;
Yang, Hong;
Zhuang, Li

Publication type:

Article

Karyopherin alpha 2 expression is a novel diagnostic and prognostic factor for colorectal cancer.

Published in:

Oncology Letters, 2017, v. 13, n. 3, p. 1194, doi. 10.3892/ol.2017.5579

By:

LEI YU;
GUIYU WANG;
QIAN ZHANG;
LI GAO;
RUI HUANG;
YINGGANG CHEN;
QINGCHAO TANG;
JIN LIU;
CHUNJIA LIU;
HONGWEI WANG;
XISHAN WANG

Publication type:

Article

Nuclear import of histones.

Published in:

Biochemical Society Transactions, 2020, v. 48, n. 6, p. 2753, doi. 10.1042/BST20200572

By:

Bernardes, Natalia Elisa;
Chook, Yuh Min

Publication type:

Article

Interleukin 10 promotes growth and invasion of glioma cells by up-regulating KPNA 2 .

Published in:

2019

By:

Zhang, Zihao;
Huang, Xiaoming;
Li, Jie;
Fan, Haitao;
Yang, Fan;
Zhang, Rui;
Yang, Yihang;
Feng, Shaobin;
He, Dong;
Sun, Wei;
Xin, Tao

Publication type:

journal article

Reactive Oxygen Species-Mediated DJ-1 Monomerization Modulates Intracellular Trafficking Involving Karyopherin β2.

Published in:

Molecular & Cellular Biology, 2014, v. 34, n. 16, p. 3024, doi. 10.1128/MCB.00286-14

By:

Björkblom, Benny;
Maple-Grødem, Jodi;
Puno, Marc Rhyan;
Odell, Mark;
Larsen, Jan Petter;
Møller, Simon Geir

Publication type:

Article

Zika virus infection affects the integrity of α- and β-karyopherins.

Published in:

2024

By:

Castillo, Jonathan Hernández;
Palacios Rápalo, Selvin Noé;
del Ángel, Rosa María

Publication type:

Abstract

Nuclear localization signals for four distinct karyopherin-β nuclear import systems.

Published in:

Biochemical Journal, 2015, v. 468, n. 3, p. 353, doi. 10.1042/BJ20150368

By:

Soniat, Michael;
Yuh Min Chook

Publication type:

Article

Diversification of importin-α isoforms in cellular trafficking and disease states.

Published in:

Biochemical Journal, 2015, v. 466, n. 1, p. 13, doi. 10.1042/BJ20141186

By:

Pumroy, Ruth A.;
Cingolani, Gino

Publication type:

Article

A multifunctional, multi-pathway intracellular localization signal in Huntingtin.

Published in:

Communicative & Integrative Biology, 2013, v. 6, n. 2, p. e23318-1, doi. 10.4161/cib.23318

By:

Desmond, Carly R.;
Maiuri, Tamara;
Truant, Ray

Publication type:

Article

Karyopherin alpha 2 is a novel prognostic marker and a potential therapeutic target for colon cancer.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2015, v. 34, p. 1, doi. 10.1186/s13046-015-0261-3

By:

Yu Zhang;
Meng Zhang;
Fudong Yu;
Su Lu;
Huimin Sun;
Huamei Tang;
Zhihai Peng

Publication type:

Article

Characterization of p92, Karyopherin β, Co-Purified with N-Acetylglucosamine–Bearing Nucleoporins from Rat Liver Nuclear Envelopes1.

Published in:

Journal of Biochemistry, 1996, v. 120, n. 4, p. 716, doi. 10.1093/oxfordjournals.jbchem.a021470

By:

Makifuchi, Shigehito;
Takeuchi, Masaki;
kawahire, shigeru;
Odani, Shoji;
Ichimura, Tohru;
Omata, Saburo;
Horigome, Tsuneyoshi

Publication type:

Article

Karyopherin Alpha 2 Promotes the Inflammatory Response in Rat Pancreatic Acinar Cells Via Facilitating NF-κB Activation.

Published in:

2016

By:

Cai, Yongxia;
Shen, Yanbo;
Gao, Lili;
Chen, Minmin;
Xiao, Min;
Huang, Zhongwei;
Zhang, Dongmei

Publication type:

journal article

Nuclear Transport of Yeast Proteasomes.

Published in:

Biomolecules (2218-273X), 2014, v. 4, n. 4, p. 940, doi. 10.3390/biom4040940

By:

Enenkel, Cordula

Publication type:

Article

Cloning and Characterization of Importin α in Brassica napus L.

Published in:

Crop Science, 2013, v. 53, n. 6, p. 2538, doi. 10.2135/cropsci2013.03.0174

By:

Daojie Wang;
Cuiling Yang;
Ming Lu;
Fei Huang;
Aiguang Guo;
Chunpeng Song

Publication type:

Article

Nucleocytoplasmic Shuttling of Cytoskeletal Proteins: Molecular Mechanism and Biological Significance.

Published in:

International Journal of Cell Biology, 2012, p. 1, doi. 10.1155/2012/494902

By:

Kumeta, Masahiro;
Yoshimura, Shige H.;
Hejna, James;
Takeyasu, Kunio

Publication type:

Article

Nuclear import of human histone lysine-specific demethylase LSD1.

Published in:

Journal of Biochemistry, 2014, v. 156, n. 6, p. 305, doi. 10.1093/jb/mvu042

By:

Jin, Yanhua;
Kim, Tae Young;
Kim, Min Seong;
Kim, Min Aeh;
Park, Su Hyung;
Jang, Yeun Kyu

Publication type:

Article

Importin 13: a novel mediator of nuclear import and export.

Published in:

EMBO Journal, 2001, v. 20, n. 14, p. 3685, doi. 10.1093/emboj/20.14.3685

By:

Mingot, José‐Manuel;
Kostka, Susanne;
Kraft, Regine;
Hartmann, Enno;
Görlich, Dirk

Publication type:

Article

Importin‐11, a nuclear import receptor for the ubiquitin‐conjugating enzyme, UbcM2.

Published in:

EMBO Journal, 2000, v. 19, n. 20, p. 5502, doi. 10.1093/emboj/19.20.5502

By:

Plafker, Scott M.;
Macara, Ian G.

Publication type:

Article

The Sequence [RRKLPVGRS] Is a Nuclear Localization Signal for Importin 8 Binding (NLS8): A Chemical Biology and Bioinformatics Study.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 6, p. 2814, doi. 10.3390/ijms26062814

By:

Panagiotopoulos, Athanasios A.;
Kalyvianaki, Konstantina;
Angelidaki, Aikaterini;
Dellis, Dimitris;
Panagiotidis, Christos A.;
Kampa, Marilena;
Castanas, Elias

Publication type:

Article

Puf6 and Loc1 Are the Dedicated Chaperones of Ribosomal Protein Rpl43 in Saccharomyces cerevisiae.

Published in:

International Journal of Molecular Sciences, 2019, v. 20, n. 23, p. 5941, doi. 10.3390/ijms20235941

By:

Liang, Kai-Jen;
Yueh, Le-Yun;
Hsu, Ning-Hsiang;
Lai, Jui-Sheng;
Lo, Kai-Yin

Publication type:

Article

Changes associated with Ebola virus adaptation to novel species.

Published in:

Bioinformatics, 2017, v. 33, n. 13, p. 1911, doi. 10.1093/bioinformatics/btx065

By:

Pappalardo, Morena;
Reddin, Ian G.;
Cantoni, Diego;
Rossman, Jeremy S.;
Michaelis, Martin;
Wass, Mark N.

Publication type:

Article

Mechanism of exportin retention in the cell nucleus.

Published in:

Journal of Cell Biology, 2024, v. 223, n. 2, p. 1, doi. 10.1083/jcb.202306094

By:

Kapinos, Larisa E.;
Kalita, Joanna;
Kassianidou, Elena;
Rencurel, Chantal;
Lim, Roderick Y. H.

Publication type:

Article

Karyopherins regulate nuclear pore complex barrier and transport function.

Published in:

Journal of Cell Biology, 2017, v. 216, n. 11, p. 3609, doi. 10.1083/jcb.201702092

By:

Kapinos, Larisa E.;
Binlu Huang;
Rencurel, Chantal;
Lim, Roderick Y. H.

Publication type:

Article

Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS.

Published in:

Nature Neuroscience, 2015, v. 18, n. 9, p. 1226, doi. 10.1038/nn.4085

By:

Jovičić, Ana;
Mertens, Jerome;
Boeynaems, Steven;
Bogaert, Elke;
Chai, Noori;
Yamada, Shizuka B;
Paul, Joseph W;
Sun, Shuying;
Herdy, Joseph R;
Bieri, Gregor;
Kramer, Nicholas J;
Gage, Fred H;
Van Den Bosch, Ludo;
Robberecht, Wim;
Gitler, Aaron D

Publication type:

Article

Upregulated Expression of Karyopherin α2 is Involved in Neuronal Apoptosis Following Intracerebral Hemorrhage in Adult Rats.

Published in:

Cellular & Molecular Neurobiology, 2016, v. 36, n. 5, p. 755, doi. 10.1007/s10571-015-0258-7

By:

Xu, Zhiwei;
Chen, Jianping;
Shi, Jiansheng;
Zhao, Jianmei;
Wang, Jun;
Ji, Yuhong;
Han, Lijian;
Zhu, Liang;
Li, Xiaohong;
Zhang, Dongmei

Publication type:

Article

Chikungunya virus capsid protein contains nuclear import and export signals.

Published in:

Virology Journal, 2013, v. 10, n. 1, p. 1, doi. 10.1186/1743-422X-10-269

By:

Thomas, Saijo;
Rai, Jagdish;
John, Lijo;
Schaefer, Stephan;
Pützer, Brigitte M.;
Herchenröder, Ottmar

Publication type:

Article

The Ebola Virus Interferon Antagonist VP24 Directly Binds STAT1 and Has a Novel, Pyramidal Fold.

Published in:

PLoS Pathogens, 2012, v. 8, n. 2, p. 1, doi. 10.1371/journal.ppat.1002550

By:

Zhang, Adrianna P. P.;
Bornholdt, Zachary A.;
Liu, Tong;
Abelson, Dafna M.;
Lee, David E.;
Sheng Li;
Woods Jr., Virgil L.;
Saphire, Erica Ollmann

Publication type:

Article

Nuclear transport receptor karyopherin-α2 promotes malignant breast cancer phenotypes in vitro.

Published in:

Oncogene, 2012, v. 31, n. 16, p. 2101, doi. 10.1038/onc.2011.403

By:

Noetzel, E;
Rose, M;
Bornemann, J;
Gajewski, M;
Knüchel, R;
Dahl, E

Publication type:

Article

The Role of TNPO3 in HIV-1 Replication.

Published in:

Molecular Biology International, 2012, p. 1, doi. 10.1155/2012/868597

By:

Diaz-Griffero, Felipe

Publication type:

Article

The Ebola Virus Interferon Antagonist VP24 Undergoes Active Nucleocytoplasmic Trafficking.

Published in:

Viruses (1999-4915), 2021, v. 13, n. 8, p. 1650, doi. 10.3390/v13081650

By:

Harrison, Angela R.;
David, Cassandra T.;
Rawlinson, Stephen M.;
Moseley, Gregory W.

Publication type:

Article