Works matching DE "KARYOPHERINS"

Results: 89

Natural mutations in key NLS amino acids regulate nucleoplasmic shuttling and replication efficiency in PRRSV.

Published in:

Frontiers in Microbiology, 2025, p. 1, doi. 10.3389/fmicb.2025.1587634

By:

Zhu, Xianchang;
Xia, Yang;
Lei, Qian;
Gan, Yu;
Jiang, Shenghai;
Huang, Lian;
Wen, Qihu;
Fu, Wei;
Zhang, Bo;
Zhang, Yi;
Xie, Shanshan;
Li, Jida

Publication type:

Article

Tumor-derived exosomal lncRNA SNHG4 promotes triple-negative breast cancer progression by targeting XPO5.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1593827

By:

Wang, Zhi-Wen;
Yang, Hou-Sheng;
Guo, Hong-Shan;
Li, Yue-Ying;
Zhong, Jin-Yun;
Jiang, Shu;
Li, Jia-Peng;
Yang, Zhong-Yi;
Zhou, Chuan-Yi;
Wang, Jun;
Liao, Xing-Hua;
Mao, Lei

Publication type:

Article

Karyopherin a2 and chromosome region maintenance protein 1 expression in meningiomas: novel biomarkers for recurrence and malignant progression.

Published in:

Journal of Neuro-Oncology, 2014, v. 118, n. 2, p. 289, doi. 10.1007/s11060-014-1423-4

By:

Gousias, Konstantinos;
Niehusmann, Pitt;
Gielen, Gerrit;
Simon, Matthias

Publication type:

Article

Nuclear karyopherin a2: a novel biomarker for infiltrative astrocytomas.

Published in:

Journal of Neuro-Oncology, 2012, v. 109, n. 3, p. 545, doi. 10.1007/s11060-012-0924-2

By:

Gousias, K.;
Becker, A.;
Simon, M.;
Niehusmann, P.

Publication type:

Article

Zika virus infection affects the integrity of α- and β-karyopherins.

Published in:

2024

By:

Castillo, Jonathan Hernández;
Palacios Rápalo, Selvin Noé;
del Ángel, Rosa María

Publication type:

Abstract

Analysis of exportins expression unveils their prognostic significance in colon adenocarcinoma: insights from public databases.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-01748-4

By:

Kalia, Punita;
Nair, Rohini Ravindran;
Yadav, Suresh Singh

Publication type:

Article

The Ebola Virus Interferon Antagonist VP24 Undergoes Active Nucleocytoplasmic Trafficking.

Published in:

Viruses (1999-4915), 2021, v. 13, n. 8, p. 1650, doi. 10.3390/v13081650

By:

Harrison, Angela R.;
David, Cassandra T.;
Rawlinson, Stephen M.;
Moseley, Gregory W.

Publication type:

Article

Nucleocytoplasmic Trafficking Perturbation Induced by Picornaviruses.

Published in:

Viruses (1999-4915), 2021, v. 13, n. 7, p. 1210, doi. 10.3390/v13071210

By:

Lizcano-Perret, Belén;
Michiels, Thomas

Publication type:

Article

KPNA2 Contributes to the Inflammatory Processes in Synovial Tissue of Patients with Rheumatoid Arthritis and SW982 Cells.

Published in:

Inflammation, 2015, v. 38, n. 6, p. 2224, doi. 10.1007/s10753-015-0205-2

By:

Liu, Zhongbing;
Zhang, Dongmei;
Sun, Chi;
Tao, Ran;
Xu, Xinbao;
Xu, Libin;
Cheng, Hongbing;
Xiao, Min;
Wang, Youhua

Publication type:

Article

KPNA2 is a nuclear export protein that contributes to aberrant localisation of key proteins and poor prognosis of breast cancer.

Published in:

British Journal of Cancer, 2015, v. 112, n. 12, p. 1929, doi. 10.1038/bjc.2015.165

By:

Alshareeda, A T;
Negm, O H;
Green, A R;
Nolan, C C;
Tighe, P;
Albarakati, N;
Sultana, R;
Madhusudan, S;
Ellis, I O;
Rakha, E A

Publication type:

Article

Importin‐11, a nuclear import receptor for the ubiquitin‐conjugating enzyme, UbcM2.

Published in:

EMBO Journal, 2000, v. 19, n. 20, p. 5502, doi. 10.1093/emboj/19.20.5502

By:

Plafker, Scott M.;
Macara, Ian G.

Publication type:

Article

Nuclear–Cytoplasmic Shuttling of the Usher Syndrome 1G Protein SANS Differs from Its Paralog ANKS4B.

Published in:

Cells (2073-4409), 2024, v. 13, n. 22, p. 1855, doi. 10.3390/cells13221855

By:

Fritze, Jacques S.;
Stiehler, Felizitas F.;
Wolfrum, Uwe

Publication type:

Article

Controlling the Gatekeeper: Therapeutic Targeting of Nuclear Transport.

Published in:

Cells (2073-4409), 2018, v. 7, n. 11, p. 221, doi. 10.3390/cells7110221

By:

Kosyna, Friederike K.;
Depping, Reinhard

Publication type:

Article

CLAVATA3 mediated simultaneous control of transcriptional and post-translational processes provides robustness to the WUSCHEL gradient.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26586-0

By:

Plong, Alexander;
Rodriguez, Kevin;
Alber, Mark;
Chen, Weitao;
Reddy, G. Venugopala

Publication type:

Article

Recapitulation of selective nuclear import and export with a perfectly repeated 12mer GLFG peptide.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-24292-5

By:

Ng, Sheung Chun;
Güttler, Thomas;
Görlich, Dirk

Publication type:

Article

Characterization of p92, Karyopherin β, Co-Purified with N-Acetylglucosamine–Bearing Nucleoporins from Rat Liver Nuclear Envelopes1.

Published in:

Journal of Biochemistry, 1996, v. 120, n. 4, p. 716, doi. 10.1093/oxfordjournals.jbchem.a021470

By:

Makifuchi, Shigehito;
Takeuchi, Masaki;
kawahire, shigeru;
Odani, Shoji;
Ichimura, Tohru;
Omata, Saburo;
Horigome, Tsuneyoshi

Publication type:

Article

Characterization of the subcellular localization and nuclear import molecular mechanisms of herpes simplex virus 1 UL2.

Published in:

Biological Chemistry, 2017, v. 398, n. 4, p. 509, doi. 10.1515/hsz-2016-0268

By:

Mingsheng Cai;
Zebin Huang;
Zongmin Liao;
Tao Chen;
Ping Wang;
Si Jiang;
Daixiong Chen;
Tao Peng;
Yun Bian;
Gengde Hong;
Hang Yang;
Zhancheng Zeng;
Xiaowei Li;
Meili Li

Publication type:

Article

The C2 protein of Bhendi yellow vein mosaic virus plays an important role in symptom determination and virus replication.

Published in:

Virus Genes, 2014, v. 48, n. 1, p. 203, doi. 10.1007/s11262-013-0992-1

By:

Chandran, Sam;
Jeyabharathy, C.;
Usha, R.

Publication type:

Article

The Role of TNPO3 in HIV-1 Replication.

Published in:

Molecular Biology International, 2012, p. 1, doi. 10.1155/2012/868597

By:

Diaz-Griffero, Felipe

Publication type:

Article

Karyopherin Alpha Proteins Regulate Oligodendrocyte Differentiation.

Published in:

PLoS ONE, 2017, v. 12, n. 1, p. 1, doi. 10.1371/journal.pone.0170477

By:

Laitman, Benjamin M.;
Mariani, John N.;
Zhang, Chi;
Sawai, Setsu;
John, Gareth R.

Publication type:

Article

Karyopherin Alpha 2 Promotes the Inflammatory Response in Rat Pancreatic Acinar Cells Via Facilitating NF-κB Activation.

Published in:

2016

By:

Cai, Yongxia;
Shen, Yanbo;
Gao, Lili;
Chen, Minmin;
Xiao, Min;
Huang, Zhongwei;
Zhang, Dongmei

Publication type:

journal article

Puf6 and Loc1 Are the Dedicated Chaperones of Ribosomal Protein Rpl43 in Saccharomyces cerevisiae.

Published in:

International Journal of Molecular Sciences, 2019, v. 20, n. 23, p. 5941, doi. 10.3390/ijms20235941

By:

Liang, Kai-Jen;
Yueh, Le-Yun;
Hsu, Ning-Hsiang;
Lai, Jui-Sheng;
Lo, Kai-Yin

Publication type:

Article

HIV-1 Vpr antagonizes innate immune activation by targeting karyopherin-mediated NF-κB/IRF3 nuclear transport.

Published in:

eLife, 2020, p. 1, doi. 10.7554/eLife.60821

By:

Khan, Hataf;
Sumner, Rebecca P.;
Rasaiyaah, Jane;
Choon Ping Tan;
Rodriguez-Plata, Maria Teresa;
Van Tulleken, Chris;
Fink, Douglas;
Zuliani-Alvarez, Lorena;
Thorne, Lucy;
Stirling, David;
Milne, Richard S. B.;
Towers, Greg J.

Publication type:

Article

Nucleocytoplasmic Communication in Healthy and Diseased Plant Tissues.

Published in:

Frontiers in Plant Science, 2021, v. 12, p. 1, doi. 10.3389/fpls.2021.719453

By:

Lüdke, Daniel;
Rohmann, Philipp F. W.;
Wiermer, Marcel

Publication type:

Article

Exportins can inhibit major mitotic assembly events in vitro: membrane fusion, nuclear pore formation, and spindle assembly.

Published in:

Nucleus (1949-1034), 2020, v. 11, n. 1, p. 178, doi. 10.1080/19491034.2020.1798093

By:

Nord, Matthew S.;
Bernis, Cyril;
Carmona, Sarah;
Garland, Dennis C.;
Travesa, Anna;
Forbes, Douglass J.

Publication type:

Article

How to operate a nuclear pore complex by Kap-centric control.

Published in:

Nucleus (1949-1034), 2015, v. 6, n. 5, p. 366, doi. 10.1080/19491034.2015.1090061

By:

Lim, Roderick Y H;
Huang, Binlu;
Kapinos, Larisa E

Publication type:

Article

A multifunctional, multi-pathway intracellular localization signal in Huntingtin.

Published in:

Communicative & Integrative Biology, 2013, v. 6, n. 2, p. e23318-1, doi. 10.4161/cib.23318

By:

Desmond, Carly R.;
Maiuri, Tamara;
Truant, Ray

Publication type:

Article

Nucleocytoplasmic Shuttling of Cytoskeletal Proteins: Molecular Mechanism and Biological Significance.

Published in:

International Journal of Cell Biology, 2012, p. 1, doi. 10.1155/2012/494902

By:

Kumeta, Masahiro;
Yoshimura, Shige H.;
Hejna, James;
Takeyasu, Kunio

Publication type:

Article

Association of overexpressed karyopherin alpha 2 with poor survival and its contribution to interleukin‐1β‐induced matrix metalloproteinase expression in oral cancer.

Published in:

Head & Neck, 2018, v. 40, n. 8, p. 1719, doi. 10.1002/hed.25145

By:

Wang, Chun‐I;
Yu, Chia‐Jung;
Huang, Yenlin;
Yi, Jui‐Shan;
Cheng, Hsing‐Wen;
Kao, Huang‐Kai;
Lao, William Wei‐Kai;
Chang, Kai‐Ping

Publication type:

Article

Zika virus NS2A protein induces the degradation of KPNA2 (karyopherin subunit alpha 2) via chaperone-mediated autophagy.

Published in:

Autophagy, 2020, v. 16, n. 12, p. 2238, doi. 10.1080/15548627.2020.1823122

By:

He, Jia;
Yang, Liping;
Chang, Peixi;
Yang, Shixing;
Lin, Shaoli;
Tang, Qiyi;
Wang, Xinping;
Zhang, Yan-Jin

Publication type:

Article

Up-Regulation of KPNB1 Involves in Neuronal Apoptosis Following Intracerebral Hemorrhage in Adult Rats.

Published in:

Neurochemical Research, 2015, v. 40, n. 11, p. 2177, doi. 10.1007/s11064-015-1706-y

By:

Dai, Aihua;
Liu, Xiaorong;
Zhang, Yu;
Han, Lijian;
Zhu, Liang;
Ni, Haidan;
Chen, Rongrong;
Cao, Maohong

Publication type:

Article

Importins and Exportins Regulating Allergic Immune Responses.

Published in:

Mediators of Inflammation, 2014, v. 2014, p. 1, doi. 10.1155/2014/476357

By:

Aggarwal, Ankita;
Agrawal, Devendra K.

Publication type:

Article

Karyopherin α-2 is a reliable marker for identification of patients with high-risk stage II colorectal cancer.

Published in:

Journal of Cancer Research & Clinical Oncology, 2017, v. 143, n. 12, p. 2493, doi. 10.1007/s00432-017-2512-5

By:

Jeong, Dongjun;
Kim, Hyeongjoo;
Ban, Seona;
Oh, Seunghyun;
Ji, Sanghee;
Kim, Doyeon;
Ahn, Tae;
Kim, Han;
Bae, Sang;
Kwon, Hyog;
Im, Jungkyun;
Lee, Moon;
Cho, Hyun;
Kim, Chang-Jin;
Baek, Moo-Jun

Publication type:

Article

Upregulation of nuclear transporter, Kpnβ1, contributes to accelerated cell proliferation- and cell adhesion-mediated drug resistance (CAM-DR) in diffuse large B-cell lymphoma.

Published in:

Journal of Cancer Research & Clinical Oncology, 2016, v. 142, n. 3, p. 561, doi. 10.1007/s00432-015-2057-4

By:

He, Song;
Miao, Xiaobing;
Wu, Yaxun;
Zhu, Xinghua;
Miao, Xianjing;
Yin, Haibing;
He, Yunhua;
Li, Chunsun;
Liu, Yushan;
Lu, Xiaoyun;
Chen, Yali;
Wang, Yuchan;
Xu, Xiaohong

Publication type:

Article

Changes associated with Ebola virus adaptation to novel species.

Published in:

Bioinformatics, 2017, v. 33, n. 13, p. 1911, doi. 10.1093/bioinformatics/btx065

By:

Pappalardo, Morena;
Reddin, Ian G.;
Cantoni, Diego;
Rossman, Jeremy S.;
Michaelis, Martin;
Wass, Mark N.

Publication type:

Article

Transportin 1 colocalization with Fused in Sarcoma (FUS) inclusions is not characteristic for amyotrophic lateral sclerosis- FUS confirming disrupted nuclear import of mutant FUS and distinguishing it from frontotemporal lobar degeneration with FUS inclusions

Published in:

Neuropathology & Applied Neurobiology, 2013, v. 39, n. 5, p. 553, doi. 10.1111/j.1365-2990.2012.01300.x

By:

Troakes, C.;
Hortobágyi, T.;
Vance, C.;
Al‐Sarraj, S.;
Rogelj, B.;
Shaw, C. E.

Publication type:

Article

Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS.

Published in:

Nature Neuroscience, 2015, v. 18, n. 9, p. 1226, doi. 10.1038/nn.4085

By:

Jovičić, Ana;
Mertens, Jerome;
Boeynaems, Steven;
Bogaert, Elke;
Chai, Noori;
Yamada, Shizuka B;
Paul, Joseph W;
Sun, Shuying;
Herdy, Joseph R;
Bieri, Gregor;
Kramer, Nicholas J;
Gage, Fred H;
Van Den Bosch, Ludo;
Robberecht, Wim;
Gitler, Aaron D

Publication type:

Article

Nuclear import of human histone lysine-specific demethylase LSD1.

Published in:

Journal of Biochemistry, 2014, v. 156, n. 6, p. 305, doi. 10.1093/jb/mvu042

By:

Jin, Yanhua;
Kim, Tae Young;
Kim, Min Seong;
Kim, Min Aeh;
Park, Su Hyung;
Jang, Yeun Kyu

Publication type:

Article

Diffusion: Molecular velcro in Flatland.

Published in:

Nature Nanotechnology, 2014, v. 9, n. 7, p. 500, doi. 10.1038/nnano.2014.131

By:

Huskens, Jurriaan

Publication type:

Article

Selective transport control on molecular velcro made from intrinsically disordered proteins.

Published in:

Nature Nanotechnology, 2014, v. 9, n. 7, p. 525, doi. 10.1038/nnano.2014.103

By:

Schleicher, Kai D.;
Dettmer, Simon L.;
Kapinos, Larisa E.;
Pagliara, Stefano;
Keyser, Ulrich F.;
Jeney, Sylvia;
Lim, Roderick Y. H.

Publication type:

Article

A tight balance of Karyopherin β1 expression is required in cervical cancer cells.

Published in:

2018

By:

Carden, Sarah;
van der Watt, Pauline;
Chi, Alicia;
Ajayi-Smith, Aderonke;
Hadley, Katie;
Leaner, Virna D.

Publication type:

journal article

Depletion of nuclear import protein karyopherin alpha 7 (KPNA7) induces mitotic defects and deformation of nuclei in cancer cells.

Published in:

2018

By:

Vuorinen, Elisa M.;
Rajala, Nina K.;
Ihalainen, Teemu O.;
Kallioniemi, Anne

Publication type:

journal article

Interleukin 10 promotes growth and invasion of glioma cells by up-regulating KPNA 2 .

Published in:

2019

By:

Zhang, Zihao;
Huang, Xiaoming;
Li, Jie;
Fan, Haitao;
Yang, Fan;
Zhang, Rui;
Yang, Yihang;
Feng, Shaobin;
He, Dong;
Sun, Wei;
Xin, Tao

Publication type:

journal article

The Ebola Virus Interferon Antagonist VP24 Directly Binds STAT1 and Has a Novel, Pyramidal Fold.

Published in:

PLoS Pathogens, 2012, v. 8, n. 2, p. 1, doi. 10.1371/journal.ppat.1002550

By:

Zhang, Adrianna P. P.;
Bornholdt, Zachary A.;
Liu, Tong;
Abelson, Dafna M.;
Lee, David E.;
Sheng Li;
Woods Jr., Virgil L.;
Saphire, Erica Ollmann

Publication type:

Article

Reactive Oxygen Species-Mediated DJ-1 Monomerization Modulates Intracellular Trafficking Involving Karyopherin β2.

Published in:

Molecular & Cellular Biology, 2014, v. 34, n. 16, p. 3024, doi. 10.1128/MCB.00286-14

By:

Björkblom, Benny;
Maple-Grødem, Jodi;
Puno, Marc Rhyan;
Odell, Mark;
Larsen, Jan Petter;
Møller, Simon Geir

Publication type:

Article

Androgen Induces a Switch from Cytoplasmic Retention to Nuclear Import of the Androgen Receptor.

Published in:

Molecular & Cellular Biology, 2013, v. 33, n. 24, p. 4766, doi. 10.1128/MCB.00647-13

By:

Li Ni;
Llewellyn, Ryan;
Kesler, Cristina T.;
Kelley, Joshua B.;
Spencer, Adam;
Snow, Chelsi J.;
Shank, Leonard;
Paschal, Bryce M.

Publication type:

Article

Rtp1p Is a Karyopherin-Like Protein Required for RNA Polymerase II Biogenesis.

Published in:

Molecular & Cellular Biology, 2013, v. 33, n. 9, p. 1756, doi. 10.1128/MCB.01449-12

By:

Gómez-Navarro, Natalia;
Peiró-Chova, Lorena;
Rodriguez-Navarro, Susana;
Polaina, Julio;
Estruch, Francisco

Publication type:

Article

Mechanism of exportin retention in the cell nucleus.

Published in:

Journal of Cell Biology, 2024, v. 223, n. 2, p. 1, doi. 10.1083/jcb.202306094

By:

Kapinos, Larisa E.;
Kalita, Joanna;
Kassianidou, Elena;
Rencurel, Chantal;
Lim, Roderick Y. H.

Publication type:

Article

Karyopherins regulate nuclear pore complex barrier and transport function.

Published in:

Journal of Cell Biology, 2017, v. 216, n. 11, p. 3609, doi. 10.1083/jcb.201702092

By:

Kapinos, Larisa E.;
Binlu Huang;
Rencurel, Chantal;
Lim, Roderick Y. H.

Publication type:

Article

Structure of transportin SR2, a karyopherin involved in human disease, in complex with Ran.

Published in:

Acta Crystallographica: Section F, Structural Biology Communications, 2014, v. 70, n. 6, p. 723, doi. 10.1107/S2053230X14009492

By:

Tsirkone, Vicky G.;
Beutels, Katrien G.;
Demeulemeester, Jonas;
Debyser, Zeger;
Christ, Frauke;
Strelkov, Sergei V.

Publication type:

Article