Works matching DE "JNK mitogen-activated protein kinases"

Results: 347

NKCC1 promotes proliferation, invasion and migration in human gastric cancer cells via activation of the MAPK-JNK/EMT signaling pathway.

Published in:

Journal of Cancer, 2021, v. 12, n. 1, p. 253, doi. 10.7150/jca.49709

By:

Jun-fu Wang;
Kun Zhao;
Ye-yang Chen;
Yue Qiu;
Jin-hui Zhu;
Bo-pei Li;
Zheng Wang;
Jun-qiang Chen

Publication type:

Article

Signals That Tell Fly Neurons to Extend or Retract.

Published in:

PLoS Biology, 2006, v. 4, n. 11, p. 1892, doi. 10.1371/journal.pbio.0040391

By:

Chanut, Françoise

Publication type:

Article

Mitochondrial HSP70 cognate-mediated differential expression of JNK1/2 in the pollution stressed grey mullets, Mugil cephalus.

Published in:

Fish Physiology & Biochemistry, 2012, v. 38, n. 5, p. 1257, doi. 10.1007/s10695-012-9614-4

By:

Padmini, E.;
Vijaya Geetha, B.

Publication type:

Article

Role of emodin to prevent gastrointestinal cancers: recent trends and future prospective.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02240-9

By:

Thakral, Falak;
Prasad, Bhairav;
Sehgal, Rippin;
Gupta, Saurabh;
Sharma, Ujjawal;
Singh, Bikram Jit;
Sharma, Bunty;
Tuli, Hardeep Singh;
Haque, Shafiul;
Ahmad, Faraz

Publication type:

Article

Role of emodin to prevent gastrointestinal cancers: recent trends and future prospective.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02240-9

By:

Thakral, Falak;
Prasad, Bhairav;
Sehgal, Rippin;
Gupta, Saurabh;
Sharma, Ujjawal;
Singh, Bikram Jit;
Sharma, Bunty;
Tuli, Hardeep Singh;
Haque, Shafiul;
Ahmad, Faraz

Publication type:

Article

c-Jun N-Terminal Kinase (JNK) and p38 Play Different Roles in Age-Related Purkinje Cell Death in Murine Organotypic Culture.

Published in:

Cerebellum, 2011, v. 10, n. 2, p. 281, doi. 10.1007/s12311-010-0244-z

By:

Repici, Mariaelena;
Wehrlé, Rosine;
Antoniou, Xanthi;
Borsello, Tiziana;
Dusart, Isabelle

Publication type:

Article

Yomogin, Isolated from Artemisia iwayomogi , Inhibits Neuroinflammation Stimulated by Lipopolysaccharide via Regulating MAPK Pathway.

Published in:

Antioxidants, 2023, v. 12, n. 1, p. 106, doi. 10.3390/antiox12010106

By:

Kim, Jin Hee;
Ju, In Gyoung;
Kim, Namkwon;
Huh, Eugene;
Son, So-Ri;
Hong, Joon Pyo;
Choi, Yujin;
Jang, Dae Sik;
Oh, Myung Sook

Publication type:

Article

Structural Basis and Biological Consequences for JNK2/3 Isoform Selective Aminopyrazoles.

Published in:

Scientific Reports, 2015, p. 8047, doi. 10.1038/srep08047

By:

Park, HaJeung;
Iqbal, Sarah;
Hernandez, Pamela;
Mora, Rudy;
Zheng, Ke;
Feng, Yangbo;
LoGrasso, Philip

Publication type:

Article

The Anti-neuroinflammatory Activity of Tectorigenin Pretreatment via Downregulated NF-κB and ERK/JNK Pathways in BV-2 Microglial and Microglia Inactivation in Mice With Lipopolysaccharide.

Published in:

Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2018.00462

By:

Lim, Hye-Sun;
Kim, Yu Jin;
Kim, Bu-Yeo;
Park, Gunhyuk;
Jeong, Soo-Jin

Publication type:

Article

AS601245, a c-Jun NH2-terminal kinase (JNK) inhibitor, reduces axon/dendrite damage and cognitive deficits after global cerebral ischaemia in gerbils.

Published in:

2008

By:

Carboni, S.;
Boschert, U.;
Gaillard, P.;
Gotteland, J.-P.;
Gillon, J.-Y.;
Vitte, P.-A.

Publication type:

journal article

Cryptotanshinone inhibits chemotactic migration in macrophages through negative regulation of the PI3K signaling pathway.

Published in:

2007

By:

Don, M.-J.;
Liao, J.-F.;
Lin, L.-Y.;
Chiou, W.-F.

Publication type:

journal article

The effects of cardamonin on lipopolysaccharide-induced inflammatory protein production and MAP kinase and NFκB signalling pathways in monocytes/macrophages.

Published in:

British Journal of Pharmacology, 2006, v. 149, n. 2, p. 188, doi. 10.1038/sj.bjp.0706856

By:

Hatziieremia, S.;
Gray, A. I.;
Ferro, V. A.;
Paul, A.;
Plevin, R.

Publication type:

Article

Role of JNK signalling pathway and platelet-lymphocyte aggregates in myocardial ischemia-reperfusion injury and the cardioprotective effect of ischemic postconditioning in rats.

Published in:

Molecular Medicine Reports, 2018, v. 18, n. 6, p. 5237, doi. 10.3892/mmr.2018.9545

By:

Ren, Faxin;
Mu, Nan;
Gao, Mingxiao;
Sun, Jing;
Zhang, Chuanhuan;
Sun, Xiaojian;
Li, Liudong;
Li, Jun;
Liu, Tong;
Tse, Gary;
Dong, Mei

Publication type:

Article

Spleen tyrosine kinase promotes NLR family pyrin domain containing 3 inflammasome‑mediated IL‑1β secretion via c‑Jun N‑terminal kinase activation and cell apoptosis during diabetic nephropathy.

Published in:

Molecular Medicine Reports, 2018, v. 18, n. 2, p. 1995, doi. 10.3892/mmr.2018.9164

By:

Qiao, Yingchun;
Tian, Xixi;
Men, Li;
Li, Shengyu;
Chen, Yufeng;
Xue, Meiting;
Hu, Yahui;
Zhou, Pengfei;
Long, Guangfeng;
Shi, Yue;
Liu, Ruiqing;
Liu, Yunde;
Qi, Zhi;
Cui, Yujie;
Shen, Yanna

Publication type:

Article

MG‑132 reverses multidrug resistance by activating the JNK signaling pathway in FaDu/T cells.

Published in:

Molecular Medicine Reports, 2018, v. 18, n. 2, p. 1820, doi. 10.3892/mmr.2018.9138

By:

Ma, Juke;
Lv, Zhenghua;
Liu, Xiuxiu;
Liu, Xianfang;
Xu, Wei

Publication type:

Article

Astragaloside IV downregulates the expression of MDR1 in Bel‑7402/FU human hepatic cancer cells by inhibiting the JNK/c‑Jun/AP‑1 signaling pathway.

Published in:

Molecular Medicine Reports, 2017, v. 16, n. 3, p. 2761, doi. 10.3892/mmr.2017.6924

By:

PEI‑PEI WANG;
JIA‑JIE LUAN;
WEN‑KE XU;
LIN WANG;
DU‑JUAN XU;
CHUN‑YAN YANG;
YAN‑HONG ZHU;
YA‑QIN WANG

Publication type:

Article

Sorafenib inhibits cancer side population cells by targeting c-Jun N-terminal kinase signaling.

Published in:

Molecular Medicine Reports, 2015, v. 12, n. 6, p. 8247, doi. 10.3892/mmr.2015.4422

By:

JONG BIN KIM;
MINJONG LEE;
SEO-YOUNG PARK;
SEULKI LEE;
HYE RI KIM;
HYO-SUK LEE;
JUNG-HWAN YOON;
YOON JUN KIM

Publication type:

Article

JNK1-mediated phosphorylation of Smac/DIABLO at the serine 6 residue is functionally linked to its mitochondrial release during TNF-α-induced apoptosis of HeLa cells.

Published in:

Molecular Medicine Reports, 2014, v. 10, n. 6, p. 3205, doi. 10.3892/mmr.2014.2625

By:

BYOUNGDUCK PARK

Publication type:

Article

Osteoprotegerin promotes the proliferation of chondrocytes and affects the expression of ADAMTS-5 and TIMP-4 through MEK/ERK signaling.

Published in:

Molecular Medicine Reports, 2013, v. 8, n. 6, p. 1669, doi. 10.3892/mmr.2013.1717

By:

ZHI-YUN FENG;
ZHEN-NIAN HE;
BIN ZHANG;
ZHONG CHEN

Publication type:

Article

JNK inhibitor SP600125 enhances TGF-β-induced apoptosis of RBE human cholangiocarcinoma cells in a Smad-dependent manner.

Published in:

Molecular Medicine Reports, 2013, v. 8, n. 6, p. 1623, doi. 10.3892/mmr.2013.1711

By:

YOUZHI LIN;
BINHAO ZHANG;
HUIFANG LIANG;
YULEI LU;
XI AI;
BIXIANG ZHANG;
XIAOPING CHEN

Publication type:

Article

Regulation of Stress-Activated Kinases in Response to Tacaribe Virus Infection and Its Implications for Viral Replication.

Published in:

Viruses (1999-4915), 2022, v. 14, n. 9, p. 2018, doi. 10.3390/v14092018

By:

Holzerland, Julia;
Fénéant, Lucie;
Groseth, Allison

Publication type:

Article

Contrast Expression Patterns of JNK1 During Sex Reversal of the Rice-Field Eel.

Published in:

Journal of Experimental Zoology Part B: Molecular & Developmental Evolution, 2010, v. 314B, n. 3, p. 242, doi. 10.1002/jez.b.21332

By:

YA-MEI XIAO;
LILI CHEN;
JIAO LIU;
WEN-BIN LIU;
HEGE CHEN;
LI-JUN ZOU;
YUN LIU;
DAVID WAN-CHENG LI

Publication type:

Article

A multifunctional alanine-rich anti-inflammatory peptide BCP61 showed potent inhibitory effects by inhibiting both NF-κB and MAPK expression.

Published in:

Inflammation, 2017, v. 40, n. 2, p. 688, doi. 10.1007/s10753-017-0515-7

By:

Choi, Yun;
Choi, Yoon;
Kim, Young;
Rahman, Md.;
Pradeep, G.;
Yoo, Jin;
Suh, Joo-Won

Publication type:

Article

Effect of Donor JNK Signal Transduction Inhibition on Transplant Outcome in Brain Dead Rat Model.

Published in:

Inflammation, 2012, v. 35, n. 1, p. 122, doi. 10.1007/s10753-011-9296-6

By:

Chen, Lu;
Xu, Danfeng;
Gao, Yi;
Cui, Xingang;
Du, Zunguo;
Ding, Qiang;
Wang, Xiang

Publication type:

Article

SP600125 Attenuates Nicotine-Related Aortic Aneurysm Formation by Inhibiting Matrix Metalloproteinase Production and CC Chemokine-Mediated Macrophage Migration.

Published in:

Mediators of Inflammation, 2016, p. 1, doi. 10.1155/2016/9142425

By:

Guo, Zhen-Zhen;
Cao, Qun-An;
Li, Zong-Zhuang;
Liu, Li-Ping;
Zhang, Zhi;
Zhu, Ya-Juan;
Chu, Guang;
Dai, Qiu-Yan

Publication type:

Article

JIP1-Mediated JNK Activation Negatively Regulates Synaptic Plasticity and Spatial Memory.

Published in:

Journal of Neuroscience, 2018, v. 38, n. 15, p. 3708, doi. 10.1523/JNEUROSCI.1913-17.2018

By:

Morel, Caroline;
Sherrin, Tessi;
Kennedy, Norman J.;
Forest, Kelly H.;
Avcioglu Barutcu, Seda;
Robles, Michael;
Carpenter-Hyland, Ezekiel;
Alfulaij, Naghum;
Standen, Claire L.;
Nichols, Robert A.;
Benveniste, Morris;
Davis, Roger J.;
Todorovic, Cedomir

Publication type:

Article

NKCC1 Activation Is Required for Myelinated Sensory Neurons Regeneration through JNK-Dependent Pathway.

Published in:

Journal of Neuroscience, 2015, v. 35, n. 19, p. 7414, doi. 10.1523/JNEUROSCI.4079-14.2015

By:

Mòdol, Laura;
Santos, Daniel;
Cobianchi, Stefano;
González-Pérez, Francisco;
López-Alvarez, Víctor;
Navarro, Xavier

Publication type:

Article

Blockade of JNK and NFAT pathways attenuates orthopedic particle-stimulated osteoclastogenesis of human osteoclast precursors and murine calvarial osteolysis.

Published in:

Journal of Orthopaedic Research, 2013, v. 31, n. 1, p. 67, doi. 10.1002/jor.22200

By:

Yamanaka, Yasuhiro;
Clohisy, John C.F.;
Ito, Hiroshi;
Matsuno, Takeo;
Abu‐Amer, Yousef

Publication type:

Article

DUSP16 is an epigenetically regulated determinant of JNK signalling in Burkitt's lymphoma.

Published in:

2010

By:

Lee, S.;
Syed, N.;
Taylor, J.;
Smith, P.;
Griffin, B.;
Baens, M.;
Bai, M.;
Bourantas, K.;
Stebbing, J.;
Naresh, K.;
Nelson, M.;
Tuthill, M.;
Bower, M.;
Hatzimichael, E.;
Crook, T.

Publication type:

journal article

Ask1 and Akt act synergistically to promote ROS-dependent regeneration in Drosophila.

Published in:

PLoS Genetics, 2019, v. 15, n. 1, p. 1, doi. 10.1371/journal.pgen.1007926

By:

Santabárbara-Ruiz, Paula;
Esteban-Collado, José;
Pérez, Lidia;
Viola, Giacomo;
Abril, Josep F.;
Milán, Marco;
Corominas, Montserrat;
Serras, Florenci

Publication type:

Article

Involvement of the TLR4 (Toll-like receptor4) signaling pathway in palmitate-induced INS-1 beta cell death.

Published in:

Molecular & Cellular Biochemistry, 2011, v. 354, n. 1/2, p. 207, doi. 10.1007/s11010-011-0820-7

By:

Lee, Sung-Mi;
Choi, Sung-E;
Lee, Ji-Hyun;
Lee, Jung-Jin;
Jung, Ik-Rak;
Lee, Soo-Jin;
Lee, Kwan-Woo;
Kang, Yup

Publication type:

Article

Increased JNK1 activity contributes to the upregulation of ApoD in the apocrine secretory gland cells from axillary osmidrosis.

Published in:

Molecular & Cellular Biochemistry, 2011, v. 354, n. 1/2, p. 311, doi. 10.1007/s11010-011-0830-5

By:

Chen, Hui;
Li, Yingli;
Du, Jie;
Cao, Yan;
Li, Xiaoli

Publication type:

Article

Regulation of c-Fos and c-Jun gene expression by phospholipase C activity in adult cardiomyocytes.

Published in:

Molecular & Cellular Biochemistry, 2009, v. 327, n. 1/2, p. 229, doi. 10.1007/s11010-009-0061-1

By:

Tushi Singal;
Naranjan Dhalla

Publication type:

Article

Modulation of the c-Jun N-terminal kinase activity in the embryonic heart in response to anoxia-reoxygenation: involvement of the Ca<sup>2+</sup> and mitoK<sub>ATP</sub> channels.

Published in:

Molecular & Cellular Biochemistry, 2008, v. 313, n. 1/2, p. 133, doi. 10.1007/s11010-008-9750-4

By:

Alexandre Sarre;
Stéphany Gardier;
Fabienne Maurer;
Christophe Bonny;
Eric Raddatz

Publication type:

Article

Modulation of intracellular iron levels by oxidative stress implicates a novel role for iron in signal transduction.

Published in:

BioMetals, 2009, v. 22, n. 5, p. 855, doi. 10.1007/s10534-009-9214-7

By:

Suman Deb;
Erin Johnson;
Raquel Robalinho-Teixeira;
Marianne Wessling-Resnick

Publication type:

Article

In focus in HCB.

Published in:

2019

By:

Taatjes, Douglas J.;
Roth, Jürgen

Publication type:

Editorial

Increased c-Jun N-terminal kinase activation in human endometriotic endothelial cells.

Published in:

Histochemistry & Cell Biology, 2011, v. 135, n. 1, p. 83, doi. 10.1007/s00418-010-0770-2

By:

Uz, Yesim;
Murk, William;
Bozkurt, Idil;
Kizilay, Gulnur;
Arici, Aydin;
Kayisli, Umit

Publication type:

Article

Low-dose tributyltin triggers human chondrocyte senescence and mouse articular cartilage aging.

Published in:

Archives of Toxicology, 2023, v. 97, n. 2, p. 547, doi. 10.1007/s00204-022-03407-x

By:

Chung, Yao-Pang;
Weng, Te-I;
Chan, Ding-Cheng;
Yang, Rong-Sen;
Liu, Shing-Hwa

Publication type:

Article

Hepatocyte SHP deficiency protects mice from acetaminophen-evoked liver injury in a JNK-signaling regulation and GADD45β-dependent manner.

Published in:

Archives of Toxicology, 2018, v. 92, n. 8, p. 2563, doi. 10.1007/s00204-018-2247-3

By:

Kim, Yong-Hoon;
Noh, Jung-Ran;
Hwang, Jung Hwan;
Kim, Kyoung-Shim;
Choi, Dong-Hee;
Kim, Jae-Hoon;
Moon, Sung Je;
Choi, Ji Hyun;
Hérault, Yann;
Lee, Tae Geol;
Choi, Hueng-Sik;
Lee, Chul-Ho

Publication type:

Article

Japanese encephalitis virus induces apoptosis by the IRE1/JNK pathway of ER stress response in BHK-21 cells.

Published in:

2016

By:

Huang, Mingjie;
Xu, Ahui;
Wu, Xiaoyu;
Zhang, Yanni;
Guo, Yunli;
Guo, Fenglin;
Pan, Zishu;
Kong, Lingbao

Publication type:

Report

Tob1 enhances radiosensitivity of breast cancer cells involving the JNK and p38 pathways.

Published in:

Cell Biology International, 2015, v. 39, n. 12, p. 1425, doi. 10.1002/cbin.10545

By:

Wu, Dapeng;
Zhou, Weijie;
Wang, Shunchang;
Zhou, Zhenyu;
Wang, Sheng;
Chen, Lei

Publication type:

Article

Compound K protects MIN6N8 pancreatic β-cells against palmitate-induced apoptosis through modulating SAPK/JNK activation.

Published in:

Cell Biology International, 2010, v. 34, n. 1, p. 75, doi. 10.1042/CBI20090020

By:

Kyong Kim;
Dong-Hyun Kim;
Hye Young Kim

Publication type:

Article

Anti-apoptotic action of hydrogen sulfide is associated with early JNK inhibition

Published in:

Cell Biology International, 2009, v. 33, n. 10, p. 1095, doi. 10.1016/j.cellbi.2009.06.029

By:

Shi, Sa;
Li, Qing-song;
Li, Hong;
Zhang, Li;
Xu, Man;
Cheng, Jia-li;
Peng, Cheng-hai;
Xu, Chang-qing;
Tian, Ye

Publication type:

Article

JNK-binding protein 1 regulates NF-κB activation through TRAF2 and TAK1

Published in:

Cell Biology International, 2009, v. 33, n. 3, p. 364, doi. 10.1016/j.cellbi.2009.01.003

By:

Yamaguchi, Tadayuki;
Miyashita, Chiaki;
Koyano, Satoru;
Kanda, Hiromi;
Yoshioka, Katsuji;
Shiba, Tadayoshi;
Takamatsu, Nobuhiko;
Ito, Michihiko

Publication type:

Article

Roles of p38 and JNK protein kinase pathways activated by compound cantharidin capsules containing serum on proliferation inhibition and apoptosis of human gastric cancer cell line.

Published in:

Experimental & Therapeutic Medicine, 2017, v. 14, n. 2, p. 1809, doi. 10.3892/etm.2017.4704

By:

YONGHAO SUN;
DEJUAN ZHANG;
MAO MAO;
YANGPING LU;
NING JIAO

Publication type:

Article

The -822G/A polymorphism in the promoter region of the MAP4K5 gene is associated with reduced risk of type 2 diabetes in Chinese Hans from Shanghai.

Published in:

Journal of Human Genetics, 2006, v. 51, n. 7, p. 605, doi. 10.1007/s10038-006-0402-9

By:

Yanyun Gu;
Tianhong Luo;
Jian Yang;
Di Zhang;
Meng Dai;
Weixia Jian;
Sheng Zheng;
Wenzhong Zhou;
Weibin Zhou;
Yixing Wu;
Yun Liu;
Youping Liu;
Jiping Li;
Xiaoyan Xie;
Guo Li;
Min Luo

Publication type:

Article

Diverse Roles of JNK and MKK Pathways in the Brain.

Published in:

Journal of Signal Transduction, 2012, p. 1, doi. 10.1155/2012/459265

By:

Yamasaki, Tokiwa;
Kawasaki, Hiroshi;
Nishina, Hiroshi

Publication type:

Article

The pharmacological inhibition of JNK-pathway reduces severity of Spinal Muscular Atrophy in mice.

Published in:

2018

By:

Boido, Marina;
Schellino, Roberta;
Biggi, SIlvia;
Borsell, Tiziana;
Vercelli, Alessandro

Publication type:

Abstract

Scaffold Proteins in Mammalian MAP Kinase Cascades.

Published in:

Journal of Biochemistry, 2004, v. 135, n. 6, p. 657, doi. 10.1093/jb/mvh079

By:

Yoshioka, Katsuji

Publication type:

Article

Functions of MAP Kinases: Insights from Gene-Targeting Studies.

Published in:

Journal of Biochemistry, 2004, v. 135, n. 6, p. 653, doi. 10.1093/jb/mvh078

By:

Kuida, Keisuke;
Boucher, Diane M.

Publication type:

Article