Works about JAK-STAT pathway

Results: 1722

Allicin Ameliorated High-glucose Peritoneal Dialysis Solution-induced Peritoneal Fibrosis in Rats via the JAK2/STAT3 Signaling Pathway.

Published in:

Cell Biochemistry & Biophysics, 2025, v. 83, n. 2, p. 1847, doi. 10.1007/s12013-024-01593-2

By:

Gan, Linwang;
Geng, Lei;
Li, Qiancheng;
Zhang, Liling;
Huang, Yan;
Lin, Jiaru;
Ou, Santao

Publication type:

Article

Sirt4 Overexpression Modulates the JAK2/STAT3 and PI3K/AKT/mTOR Axes to Alleviate Sepsis-Induced Acute Lung Injury.

Published in:

Cell Biochemistry & Biophysics, 2025, v. 83, n. 2, p. 1785, doi. 10.1007/s12013-024-01588-z

By:

Xie, Cancan;
Wang, Ting;
Liu, Anmin;
Huang, Bing;
Zeng, Weizhong;
Li, Zhengrong;
Peng, Suna;
Wu, Shuanghua

Publication type:

Article

Dual role of miR-155 and exosomal miR-155 in tumor angiogenesis: implications for cancer progression and therapy.

Published in:

European Journal of Medical Research, 2025, v. 30, n. 1, p. 1, doi. 10.1186/s40001-025-02618-z

By:

Hussain, Qusay Mohammed;
Al-Hussainy, Ali Fawzi;
Sanghvi, Gaurav;
Roopashree, R.;
Kashyap, Aditya;
Anand, D. Alex;
Panigrahi, Rajashree;
Shavazi, Nargiz;
Taher, Sada Ghalib;
Alwan, Mariem;
Jawad, Mahmood;
Mushtaq, Hiba

Publication type:

Article

Role of USP10/METTL3/CXCR4 Axis in Immunotherapy of Castration-Resistant Prostate Cancer.

Published in:

Iranian Journal of Allergy, Asthma & Immunology, 2025, v. 24, n. 3, p. 334, doi. 10.18502/ijaai.v24i3.18683

By:

Wu Chen;
Lijun Xu;
Haibo Deng;
Zhenyan Zhu;
Dongrong Yang

Publication type:

Article

Single-cell transcriptomic analysis deciphers the inflammatory microenvironment characterized by CXCL9+ fibroblasts and ACKR1+ endothelial cells in immune-related myocarditis.

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06551-x

By:

Sun, Boyu;
Xun, Ziyu;
Zhou, Zixiang;
Zhang, Nan;
Piao, Mingjian;
Li, Chengjie;
Li, Jiongyuan;
Li, Shuofeng;
Zhang, Longhao;
Chen, Xiangqi;
Wang, Hanping;
Zhao, Haitao

Publication type:

Article

microRNA-34 mediates a negative feedback loop in the JAK-STAT pathway to attenuate immune overactivation in an invertebrate.

Published in:

Cell Communication & Signaling, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12964-025-02230-y

By:

Zuo, Hongliang;
Liao, Alian;
Shen, Sihui;
Wang, Youxi;
Yang, Xiya;
Weng, Shaoping;
He, Jianguo;
Xu, Xiaopeng

Publication type:

Article

Tumor progression locus 2, a new potential prognostic factor and therapeutic target in activated B-cell-like diffuse large B-cell lymphoma.

Published in:

Blood Cancer Journal, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41408-025-01299-5

By:

Yoshifuji, Kota;
Motomura, Yotaro;
Saito, Makiko;
Kawade, Genji;
Watabe, Shiori;
Yamamoto, Kouhei;
Soejima, Mai;
Nogami, Ayako;
Aoyama, Satoru;
Mori, Takehiko;
Nagao, Toshikage

Publication type:

Article

Trifunctional antibody-cytokine fusion protein formats for tumor-targeted combination of IL-15 with IL-7 or IL-21.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1498697

By:

Möller, Annika M.;
Vettermann, Sarah;
Baumann, Felix;
Pütter, Max;
Müller, Dafne

Publication type:

Article

Human umbilical cord mesenchymal stem cell therapy for atopic dermatitis through inhibition of neutrophil chemotaxis.

Published in:

Stem Cell Research & Therapy, 2025, v. 16, n. 1, p. 1, doi. 10.1186/s13287-025-04349-8

By:

Shao, Jinjin;
Xie, Zhiqi;
Ye, Zhichao;
Chen, Guoyu;
Wang, Yiru;
Zhang, Lili;
Liu, Fang;
Zhang, Siming;
Lin, Xiaobo;
Wang, Jiahong;
Chen, Ying;
Chen, Yunxiang;
Pan, Xin;
Wu, Feifei;
Pan, Ruolang;
Liang, Jinfeng;
Zhang, Lijiang

Publication type:

Article

JAK2/STAT3/HMGCS2 signaling aggravates mitochondrial dysfunction and oxidative stress in hyperuricemia-induced cardiac dysfunction.

Published in:

Molecular Medicine, 2025, v. 31, n. 1, p. 1, doi. 10.1186/s10020-025-01246-x

By:

Peng, Dewei;
He, Xiaoli;
Ren, Bowen;
Wang, Qian;
Peng, Lulu;
Jiang, Yue;
Huo, Shengqi;
Men, Lintong;
Shi, Wei;
Luo, Pengcheng;
Zhu, Mengyin;
Zhang, Cuntai;
Lv, Jiagao;
Lin, Li;
Li, Sheng

Publication type:

Article

Exploring the Mechanism of Qinzhuliangxue Mixture for Treating Skin Lesions in Atopic Dermatitis: Insights from Network Pharmacology and Experimental Validation.

Published in:

Journal of Inflammation Research, 2025, v. 18, p. 5173, doi. 10.2147/JIR.S509607

By:

Qiao, Yunxiao;
Yin, Hao;
Zhang, Haitang;
He, Qingyi;
Li, Yuting;
Sun, Lu;
Wang, Jie;
Li, Xiang;
Koh, Wan Xin;
Pottakorn, Aruncharoenphonchai;
Chu, Zewen;
Xiang, Yanwei

Publication type:

Article

Mechanism of Action of Exercise in Regulating Spontaneous Hypertension through the Janus Kinase 2/Signal Transducer and Activator of Transcription 3 Signaling Pathway.

Published in:

Journal of Physiological Investigation (JPI), 2025, v. 68, n. 2, p. 109, doi. 10.4103/ejpi.EJPI-D-24-00085

By:

Li, Yu;
Song, Xiaoju;
Dai, Lianjing;
Wang, Yangyi;
Luo, Qiong;
Lei, Lei;
Pu, Yunfei

Publication type:

Article

Exogenous Janus Kinase 617 Codon Influences Small Noncoding RNAs and Gene Expression in Ba/F3 Cells.

Published in:

Journal of Physiological Investigation (JPI), 2024, v. 67, n. 6, p. 344, doi. 10.4103/ejpi.EJPI-D-24-00047

By:

Chen, Yi-Yang;
Wang, Ying-Hsuan;
Chen, Chih-Cheng;
Huang, Cih-En;
Hsu, Chia-Chen;
Hsiao, Shu-Huei;
Leu, Yu-Wei

Publication type:

Article

IL-11/IL-11R signal inhibition by 9MW3811 remodels immune tumor microenvironment and enhances anti-tumor efficacy of PD-1 blockade.

Published in:

NPJ Precision Oncology, 2025, v. 9, n. 1, p. 1, doi. 10.1038/s41698-025-00913-w

By:

Zhang, Chang;
Jiao, Shasha;
Zeng, Dadi;
Jiang, Wen;
Wang, Rongjuan;
Zheng, Bin;
Wang, Min;
Wang, Shuang;
Gui, Xun

Publication type:

Article

The combination of SH003 and DTX induces cytotoxic cell infiltration in anti-PD1 resistant lung cancer.

Published in:

Cancer Immunology, Immunotherapy, 2025, v. 74, n. 7, p. 1, doi. 10.1007/s00262-025-04064-6

By:

Choi, Yu-Jeong;
Lee, Sang-Eun;
Kim, Daeun;
Lim, Hae-In;
Choi, Da Kyung;
Park, Bong Kyu;
Jeon, Chan-Yong;
Ko, Seong-Gyu

Publication type:

Article

Synergistic inhibition of gastric cancer cell proliferation by concanavalin A and silibinin via attenuation of the JAK/STAT3 signaling pathway and molecular docking analysis.

Published in:

Hereditas, 2025, v. 162, n. 1, p. 1, doi. 10.1186/s41065-025-00438-z

By:

Hua, Gaoyan;
Zhao, Lisha;
Zeng, Xianjing;
Luo, Liang

Publication type:

Article

Mechanism of total saponins of Ranunculus ternatus Thunb. in treatment of breast cancer based on liquid chromatography–mass spectrometry and network analysis.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1506885

By:

Zhang, Yuanxin;
Nan, Shuo;
Zhao, Wei;
Xie, Haisheng;
Miao, Jinxin;
Miao, Mingsan

Publication type:

Article

The effect of lidocaine against sepsis-induced acute lung injury in a mouse model through the JAK2/STAT3 pathway.

Published in:

PLoS ONE, 2025, v. 20, n. 5, p. 1, doi. 10.1371/journal.pone.0322653

By:

Cai, Ying;
Zhang, Hong;
Cui, Lun-Meng;
Chen, Qian;
Xie, Feng-Jie

Publication type:

Article

CLEC7A 调节 PD-L1 促进卵巢癌生长的作用及机制研究.

Published in:

Journal of New Medicine, 2025, v. 56, n. 4, p. 361, doi. 10.12464/j.issn.0253-9802.2025-0056

By:

陈瑶;
孙思柏;
许俊;
何杰

Publication type:

Article

Human papillomavirus E1 proteins inhibit RIG-I/MDA5-MAVS, TLR3-TRIF, cGAS-STING, and JAK-STAT signaling pathways to evade innate antiviral immunity.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1549766

By:

Li, Jin-Xin;
Zhang, Jing;
Li, Cheng-Hao;
Li, Yun-Fang;
Chen, Hui-Min;
Li, Tao;
Zhang, Qing;
Kong, Bei-Hua;
Wang, Pei-Hui

Publication type:

Article

Others.

Published in:: Clinical Chemistry & Laboratory Medicine, 2025, v. 63, n. 1, p. s2728, doi. 10.1515/cclm-2025-8072
Publication type:: Article

Expression of Signal Transducer and Activator of Transcription-3 in Androgenetic Alopecia: A Case-Control Study.

Published in:

2022

By:

Hassan, Akmal Saad;
Al-dhoun, Mohammad Qassim;
Shaker, Olfat Gamil;
AlOrbani, Aya M.

Publication type:

Case Study

The PRL2 phosphatase up-regulates miR-21 through activation of the JAK2/STAT3 pathway to down-regulate the PTEN tumor suppressor.

Published in:

Biochemical Journal, 2025, v. 482, n. 7, p. 341, doi. 10.1042/BCJ20240626

By:

Qinglin Li;
Yunpeng Bai;
Cavender, Sarah M.;
Yiming Miao;
Meke, Frederick Nguele;
Lasse-Opsahl, Emily L.;
Peipei Zhu;
Doody, Gina M.;
Tao, W. Andy;
Zhong-Yin Zhang

Publication type:

Article

Detection of Inflammatory Signaling in Individuals with Bardet-Biedl Syndrome Presenting Symptoms of Polycystic Kidney Disease.

Published in:

Jentashapir Journal of Cellular & Molecular Biology, 2024, v. 15, n. 2, p. 1, doi. 10.5812/jcp-140747

By:

Khouzani, Mohammad Shiravi;
Kandasamy, Krishnaveni

Publication type:

Article

Involvement of ZmMPK14 in Plant Defense Revealed by Comparative Expression Analysis.

Published in:

Bilecik Seyh Edebali University Journal of Science / Bilecik Şeyh Edebali Üniversitesi Sosyal Bilimler Dergisi, 2021, v. 8, n. 2, p. 636, doi. 10.35193/bseufbd.928182

By:

Südüpak, Mehmet Ali

Publication type:

Article

Intervention of inflammation associated with ankylosing spondylitis by triptolide promotes histone H3 Iys-27 trimethylation.

Published in:

Immunopharmacology & Immunotoxicology, 2024, v. 46, n. 6, p. 785, doi. 10.1080/08923973.2024.2402911

By:

Xu, Xiao-Han;
Zhang, Jin-Xu;
Liu, Hong-Xiao;
Zhao, Zhe;
Jiang, Jun-Yi

Publication type:

Article

Citicoline modulates inflammatory signaling pathways in the spleen of rats exposed to gamma-radiation.

Published in:

Immunopharmacology & Immunotoxicology, 2024, v. 46, n. 4, p. 564, doi. 10.1080/08923973.2024.2381759

By:

Abdel-Aziz, Nahed;
Saif-Elnasr, Mostafa

Publication type:

Article

MiR-340 affects gastric cancer cell proliferation, cycle, and apoptosis through regulating SOCS3/JAK-STAT signaling pathway.

Published in:

Immunopharmacology & Immunotoxicology, 2018, v. 40, n. 4, p. 278, doi. 10.1080/08923973.2018.1455208

By:

Xiao, Chunhong;
Hong, Hong;
Yu, Haizhong;
Yuan, Jianfen;
Guo, Chunyan;
Cao, Hongyan;
Li, Weibing

Publication type:

Article

广叶绣球菌多糖对小鼠 CD8<sup>+</sup> T 细胞介导的免疫应答调控机制.

Published in:

Mycosystema, 2023, v. 42, n. 5, p. 1163, doi. 10.13346/j.mycosystema.220251

By:

贺楷雄;
程艳芬;
云少君;
程菲儿;
曹谨玲;
冯翠萍

Publication type:

Article

Nicotine-induced activation of cholinergic receptor nicotinic alpha 5 subunit mediates the malignant behaviours of laryngeal squamous epithelial cells by interacting with RABL6.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-02051-x

By:

Shen, Yujie;
Huang, Qiang;
Yuan, Xiaohui;
Gong, Hongli;
Xu, Chengzhi;
Du, Huaidong;
Hsueh, Chi-Yao;
Zhou, Liang

Publication type:

Article

NUP43 promotes PD-L1/nPD-L1/PD-L1 feedback loop via TM4SF1/JAK/STAT3 pathway in colorectal cancer progression and metastatsis.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-02025-z

By:

Wu, Fan;
Sun, Guoqiang;
Nai, Yongjun;
Shi, Xuesong;
Ma, Yong;
Cao, Hongyong

Publication type:

Article

AMPK-induced novel phosphorylation of RUNX1 inhibits STAT3 activation and overcome imatinib resistance in chronic myelogenous leukemia (CML) subjects.

Published in:

Cell Death Discovery, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41420-023-01700-x

By:

Gayatri, Meher Bolisetti;
Kancha, Rama Krishna;
Behera, Abhayananda;
Patchva, Dorababu;
Velugonda, Nagaraj;
Gundeti, Sadasivudu;
Reddy, Aramati Bindu Madhava

Publication type:

Article

Administration of AG490 decreases the senescence of umbilical cord-mesenchymal stem cells and promotes the cytotherapeutic effect in liver fibrosis.

Published in:

Cell Death Discovery, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41420-023-01546-3

By:

Jiang, Chenhao;
Chen, Huaxin;
Kang, Yinqian;
He, Xinyi;
Huang, Jianyang;
Lu, Tongyu;
Sui, Xin;
Chen, Haitian;
Xiao, Jiaqi;
Zhang, Jiebin;
Zhang, Hanwen;
Zheng, Jun;
Yang, Yang;
Yao, Jia;
Cai, Jianye;
Zhang, Yingcai

Publication type:

Article

Polycythemia vera: diagnosis, clinical course, and current management.

Published in:

Turkish Journal of Medical Sciences, 2018, v. 48, n. 4, p. 698, doi. 10.3906/sag-1806-43

By:

BÜYÜKAŞIK, Yahya;
ALİ, Rıdvan;
AR, Cem;
TURGUT, Mehmet;
YAVUZ, Selim;
SAYDAM, Güray

Publication type:

Article

Effects of extracellular vesicles from adipose‐derived stem cells on human keloid fibroblasts via the SOCS1/JAK2/STAT3 pathway.

Published in:

Journal of Cosmetic Dermatology, 2024, v. 23, n. 4, p. 1404, doi. 10.1111/jocd.16117

By:

Ruan, Hongru;
Wang, Jie;
Shi, Hui;
Luan, Wenkang

Publication type:

Article

To explore the potential molecular mechanism of complex rose–bergamot essential oil on anti‐anxiety with facial spots based on network pharmacology.

Published in:

Journal of Cosmetic Dermatology, 2022, v. 21, n. 11, p. 6363, doi. 10.1111/jocd.15296

By:

Xin, Jin;
Xu, Xu;
Qiaoling, Ding;
Liping, Liu;
Kunqin, Ma;
Yiping, Zhang

Publication type:

Article

A prospective study examining the expression of STAT 1, 3, 6 in prurigo nodularis lesions with its immunopathogenic and therapeutic implications.

Published in:

Journal of Cosmetic Dermatology, 2022, v. 21, n. 9, p. 4009, doi. 10.1111/jocd.14709

By:

Agrawal, Diksha;
Sardana, Kabir;
Mathachan, Sinu Rose;
Bhardwaj, Minakshi;
Ahuja, Arvind;
Jain, Swasti

Publication type:

Article

基于 UPLC-Q/TOF MS 及网络药理学的丹参川芎嗪注射液抗血瘀活性成分和机制研究.

Published in:

Journal of Chinese Mass Spectrometry Society, 2020, v. 41, n. 6, p. 24, doi. 10.7538/zpxb.2019.0130

By:

董庆海;
刘慧;
刘俊丽;
林红强;
焦玉;
司雨;
刘云鹤;
王钟瑶;
刘金平;
李平亚;
李卓

Publication type:

Article

STAT activation in regulatory CD4<sup>+</sup> T cells of patients with primary sclerosing cholangitis.

Published in:

Immunity, Inflammation & Disease, 2024, v. 12, n. 4, p. 1, doi. 10.1002/iid3.1248

By:

Dold, Leona;
Kalthoff, Sandra;
Frank, Leonie;
Zhou, Taotao;
Esser, Pia;
Lutz, Philipp;
Strassburg, Christian P.;
Spengler, Ulrich;
Langhans, Bettina

Publication type:

Article

Etanercept alleviates psoriasis by reducing the Th17/Treg ratio and promoting M2 polarization of macrophages.

Published in:

Immunity, Inflammation & Disease, 2022, v. 10, n. 12, p. 1, doi. 10.1002/iid3.734

By:

Li, Xiaoqing;
Jiang, Ming;
Chen, Xia;
Sun, Weiguo

Publication type:

Article

MiR-135a biogenesis and regulation in malignancy: a new hope for cancer research and therapy.

Published in:

Cancer Biology & Medicine, 2020, v. 17, n. 3, p. 569, doi. 10.20892/j.issn.2095-3941.2020.0033

By:

Zhe Cao;
Jiangdong Qiu;
Gang Yang;
Yueze Liu;
Wenhao Luo;
Lei You;
Lianfang Zheng;
Taiping Zhang

Publication type:

Article

Melatonin reduces melanogenesis by inhibiting the paracrine effects of keratinocytes.

Published in:

Experimental Dermatology, 2023, v. 32, n. 4, p. 511, doi. 10.1111/exd.14743

By:

Yang, Siyu;
Zeng, Hongliang;
Jiang, Ling;
Fu, Chuhan;
Gao, Lijuan;
Zhang, Lan;
Zhang, Yushan;
Zhang, Xiaolin;
Zhu, Lu;
Zhang, Fan;
Chen, Jing;
Huang, Jinhua;
Zeng, Qinghai

Publication type:

Article

The JAK–STAT pathway in keloid pathogenesis: a systematic review with qualitative synthesis.

Published in:

Experimental Dermatology, 2023, v. 32, n. 5, p. 588, doi. 10.1111/exd.14747

By:

Yin, Qi;
Wolkerstorfer, Albert;
Lapid, Oren;
Niessen, Frank B.;
Van Zuijlen, Paul P. M.;
Gibbs, Susan

Publication type:

Article

Transcriptomic profiling of recessive dystrophic epidermolysis bullosa wounded skin highlights drug repurposing opportunities to improve wound healing.

Published in:

Experimental Dermatology, 2022, v. 31, n. 3, p. 420, doi. 10.1111/exd.14481

By:

Onoufriadis, Alexandros;
Proudfoot, Laura E.;
Ainali, Chrysanthi;
Torre, Denis;
Papanikolaou, Maria;
Rayinda, Tuntas;
Rashidghamat, Ellie;
Danarti, Retno;
Mellerio, Jemima E.;
Ma'ayan, Avi;
McGrath, John A.

Publication type:

Article

Molecular pathogenesis of cutaneous lymphoma—Future directions.

Published in:

Experimental Dermatology, 2020, v. 29, n. 11, p. 1062, doi. 10.1111/exd.14211

By:

Stadler, Rudolf;
Hain, Carsten;
Cieslak, Cassandra;
Stranzenbach, René

Publication type:

Article

Expression of JAK/STAT signalling in bullous pemphigoid.

Published in:

Australasian Journal of Dermatology, 2025, v. 66, n. 1, p. e10, doi. 10.1111/ajd.14389

By:

Iyengar, Laxmi;
Hosking, Patrick;
Dowsett, Joel;
Su, John

Publication type:

Article

Successful treatment of chronic severe alopecia areata with abrocitinib.

Published in:

Australasian Journal of Dermatology, 2022, v. 63, n. 2, p. 274, doi. 10.1111/ajd.13836

By:

Bennett, Michaela;
Moussa, Anthony;
Sinclair, Rodney

Publication type:

Article

A transcriptomic analysis of skeletal muscle tissues reveals promising candidate genes and pathways accountable for different daily weight gain in Hanwoo cattle.

Published in:

Scientific Reports, 2024, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-51037-9

By:

Sheet, Sunirmal;
Jang, Sun Sik;
Kim, Jae Hwan;
Park, Woncheoul;
Kim, Dahye

Publication type:

Article

Evodiae Fructus extract suppresses inflammatory response in HaCaT cells and improves house dust mite-induced atopic dermatitis in NC/Nga mice.

Published in:

Scientific Reports, 2024, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-50257-3

By:

Jin, Seong Eun;
Seo, Chang-Seob;
Jeon, Woo-Young;
Oh, Yong Jin;
Shin, Hyeun-Kyoo;
Jeong, Hye Gwang;
Ha, Hyekyung

Publication type:

Article

TWAS revealed significant causal loci for milk production and its composition in Murrah buffaloes.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-49767-x

By:

Chhotaray, Supriya;
Vohra, Vikas;
Uttam, Vishakha;
Santhosh, Ameya;
Saxena, Punjika;
Gahlyan, Rajesh Kumar;
Gowane, Gopal

Publication type:

Article