Works matching DE "JAK-STAT pathway"

Results: 1765

EFFECTS OF TANSHINONE IIA ON INTESTINAL MICROFLORA DIVERSITY AND IMMUNE FUNCTION IN RATS WITH IRRITABLE BOWEL SYNDROME.

Published in:

Acta Poloniae Pharmaceutica, 2025, v. 82, n. 1, p. 145, doi. 10.32383/appdr/203323

By:

HUIHUI MAO;
QING LI;
CHENGXIA GONG;
KANGJIAN ZHANG;
DAOBIN HAN

Publication type:

Article

CALR-mutated myeloproliferative neoplasms.

Published in:

Leukemia & Lymphoma, 2025, v. 66, n. 7, p. 1198, doi. 10.1080/10428194.2025.2465551

By:

Bellani, Valentina;
Mora, Barbara;
Iurlo, Alessandra;
Passamonti, Francesco

Publication type:

Article

Recalcitrant Prurigo Nodularis Successfully Treated with Dupilumab.

Published in:

2025

By:

Anjaneyan, Gopikrishnan;
Reddy, Smruthi;
Mathew, Lydia;
Ponnamparambath, Vimi

Publication type:

Case Study

TFF3 initiates gastric intestinal metaplasia by activating JAK2 and STAT3 under high salt conditions.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-09045-4

By:

Wang, Yanhong;
Qian, Feifei;
Shan, Baodong;
Zhang, Li;
Zhong, Jie;
Chen, Song;
Yao, Manman;
Li, Shengnan;
Cao, Xixiang;
Fei, Sujuan;
Pang, Xunlei

Publication type:

Article

JAK-STAT Signaling in Autoimmunity and Cancer.

Published in:

ImmunoTargets & Therapy, 2025, v. 15, p. 523, doi. 10.2147/ITT.S485670

By:

Parveen, Sana;
Fatma, Mariyam;
Mir, Snober Shabnam;
Dermime, Said;
Uddin, Shahab

Publication type:

Article

Integrated proteomics and transcriptomics analysis reveals key regulatory genes between ER-positive/PR-positive and ER-positive/PR-negative breast cancer.

Published in:

BMC Cancer, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12885-025-14451-y

By:

Lu, Zhengjia;
Yang, Jiao;
Feng, Yang;
Ming, Jia

Publication type:

Article

Co-Aggregation of Syndecan-3 with β-Amyloid Aggravates Neuroinflammation and Cognitive Impairment in 5×FAD Mice.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5502, doi. 10.3390/ijms26125502

By:

Ye, Fan;
Li, Mingfeng;
Liu, Min;
Wu, Xinghan;
Tian, Fan;
Gong, Yanju;
Cao, Yan;
Zhang, Jingtai;
Zhang, Xueling;
Qin, Chuan;
Zhang, Ling

Publication type:

Article

IL-23 promotes neuronal ferroptosis via IL-23R/STAT3 signaling after traumatic brain injury.

Published in:

Cell Communication & Signaling, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12964-025-02319-4

By:

Chen, Bo;
Shi, Guihong;
Xu, Jianye;
Zhang, Xu;
Zhu, Yanlin;
Li, Lei;
Wang, Cong;
Gheyret, Dilmurat;
Wang, Jinchao;
Liu, Xilei;
Cao, Yiyao;
Tan, Rui;
Zhou, Yuan;
Jiang, RongCai;
Li, Shenghui;
Li, Tuo;
Liu, Xiao;
Chen, Xin;
Yang, Guili;
Zhang, Jianning

Publication type:

Article

GOLPH3 promotes glioma progression via facilitating JAK2-STAT3 pathway activation.

Published in:

Journal of Neuro-Oncology, 2018, v. 139, n. 2, p. 269, doi. 10.1007/s11060-018-2884-7

By:

Wu, Shishuang;
Fu, Jiale;
Dong, Yu;
Yi, Qinghao;
Lu, Dong;
Wang, Weibing;
Qi, Yanhua;
Yu, Rutong;
Zhou, Xiuping

Publication type:

Article

MiR-519a functions as a tumor suppressor in glioma by targeting the oncogenic STAT3 pathway.

Published in:

Journal of Neuro-Oncology, 2016, v. 128, n. 1, p. 35, doi. 10.1007/s11060-016-2095-z

By:

Hong, Li;
Ya-wei, Liu;
Hai, Wang;
Qiang, Zhou;
Jun-jie, Li;
Huang, Annie;
Song-tao, Qi;
Yun-tao, Lu

Publication type:

Article

Activation of the sigma-1 receptor exerts cardioprotection in a rodent model of chronic heart failure by stimulation of angiogenesis.

Published in:

Molecular Medicine, 2022, v. 28, n. 1, p. 1, doi. 10.1186/s10020-022-00517-1

By:

Zhao, Xin;
Liu, Xin;
Chen, Xiuhuan;
Han, Xueyu;
Sun, Yazhou;
Fo, Yuhong;
Wang, Xiukun;
Qu, Chuan;
Yang, Bo

Publication type:

Article

Overexpression of GINS4 is associated with poor prognosis and survival in glioma patients.

Published in:

Molecular Medicine, 2021, v. 27, n. 1, p. 1, doi. 10.1186/s10020-021-00378-0

By:

Liu, Binfeng;
Liu, Zhendong;
Wang, Yanbiao;
Lian, Xiaoyu;
Han, Zhibin;
Cheng, Xingbo;
Zhu, Yongjie;
Liu, Runze;
Zhao, Yaoye;
Gao, Yanzheng

Publication type:

Article

EIF3B Promotes KRAS Gene Mutation‐Driven Colon Adenocarcinoma Progression Through the TBK1 and PI3K/AKT Signaling Pathways.

Published in:

Journal of Biochemical & Molecular Toxicology, 2025, v. 39, n. 6, p. 1, doi. 10.1002/jbt.70353

By:

Ren, Chongren;
Qin, Yaxin;
Cao, Dujuan;
Ren, Xiaojing;
Zhao, Haoliang;
Han, Jianli;
Du, Gang

Publication type:

Article

PTPRC Knockdown Inhibits Inflammation in Gouty Arthritis by Blocking the JAK2/STAT3 Signaling Pathway.

Published in:

Journal of Biochemical & Molecular Toxicology, 2025, v. 39, n. 6, p. 1, doi. 10.1002/jbt.70340

By:

Mo, Hong;
Li, Fengxia;
Zheng, Zhongying;
Ma, Zongbo;
Liu, Shuyue;
Wen, Lian;
Su, Xubo

Publication type:

Article

TFAP2A Activates ADAM8 to Promote Lung Adenocarcinoma Angiogenesis Through the JAK/STAT Signaling Pathway.

Published in:

Journal of Biochemical & Molecular Toxicology, 2025, v. 39, n. 1, p. 1, doi. 10.1002/jbt.70097

By:

Shen, Kai;
Shan, Zhidong;
Li, Yingjie;
Ji, Zeyi;
Zhou, Luyao;
Lv, Zhiliang

Publication type:

Article

LMOD1 Exerts a Tumor‐Suppressive Role in Breast Cancer by Restraining the JAK2/STAT3 Pathway.

Published in:

Journal of Biochemical & Molecular Toxicology, 2025, v. 39, n. 1, p. 1, doi. 10.1002/jbt.70092

By:

Fang, Xiansong;
Wen, Xiaoyun;
Hou, Ya;
Zhou, Liang;
Jiang, Yingjie;
Chen, Yu

Publication type:

Article

Lycorine inhibits cell proliferation and induced oxidative stress‐mediated apoptosis via regulation of the JAK/STAT3 signaling pathway in HT‐3 cells.

Published in:

Journal of Biochemical & Molecular Toxicology, 2021, v. 35, n. 10, p. 1, doi. 10.1002/jbt.22882

By:

Shang, Hui;
Jang, Xuena;
Shi, Lingyun;
Ma, Yifei

Publication type:

Article

d‐Carvone inhibits the JAK/STAT3 signaling pathway and induced the apoptotic cell death in the human gastric cancer AGS cells.

Published in:

Journal of Biochemical & Molecular Toxicology, 2021, v. 35, n. 5, p. 1, doi. 10.1002/jbt.22746

By:

Lv, Long;
Yang, Nan;
Cao, Youhong;
Dang, Junqiang;
Cheng, Likun;
El‐Sheikh, Mohamed A.;
Zhang, Yun

Publication type:

Article

Crocin treatment promotes the oxidative stress and apoptosis in human thyroid cancer cells FTC‐133 through the inhibition of STAT/JAK signaling pathway.

Published in:

Journal of Biochemical & Molecular Toxicology, 2021, v. 35, n. 1, p. 1, doi. 10.1002/jbt.22608

By:

Zhang, Yonggang;
Zhu, Meng;
Krishna Mohan, Surapaneni;
Hao, Zhi

Publication type:

Article

Paroxetine modulates immune responses by activating a JAK2/STAT3 signaling pathway.

Published in:

Journal of Biochemical & Molecular Toxicology, 2020, v. 34, n. 5, p. 1, doi. 10.1002/jbt.22464

By:

Kabiri, Mahdieh;
Hemmatpour, Anahid;
Zare, Fatemeh;
Hadinedoushan, Hossein;
Karimollah, Alireza

Publication type:

Article

Analysis of microRNA-199a-3p expression in CD4<sup>+</sup> T cells of systemic lupus erythematosus.

Published in:

Clinical Rheumatology, 2023, v. 42, n. 6, p. 1683, doi. 10.1007/s10067-023-06534-7

By:

Wang, Huijing;
Geng, Guannan;
Zhang, Danting;
Han, Fei;
Ye, Shuang

Publication type:

Article

Osteoimmunology in rheumatoid and psoriatic arthritis: potential effects of tofacitinib on bone involvement.

Published in:

Clinical Rheumatology, 2020, v. 39, n. 3, p. 727, doi. 10.1007/s10067-020-04930-x

By:

Orsolini, Giovanni;
Bertoldi, Ilaria;
Rossini, Maurizio

Publication type:

Article

Signal transducer and activator of transcription 5 is implicated in disease activity in adult and juvenile onset systemic lupus erythematosus.

Published in:

Clinical Rheumatology, 2016, v. 35, n. 6, p. 1515, doi. 10.1007/s10067-016-3250-9

By:

Meshaal, Safa;
El Refai, Rasha;
El Saie, Ahmed;
El Hawary, Rabab

Publication type:

Article

MiR-375 Mediates Chondrocyte Metabolism and Oxidative Stress in Osteoarthritis Mouse Models through the JAK2/STAT3 Signaling Pathway.

Published in:

Cells Tissues Organs, 2019, v. 208, n. 1/2, p. 13, doi. 10.1159/000504959

By:

Zou, Li-xue;
Yu, Ling;
Zhao, Xun-ming;
Liu, Jun;
Lu, Hou-gen;
Liu, Gai-wei;
Guo, Wei-chun

Publication type:

Article

The Great Atopic Dermatitis Treatment Debate: Biologics vs JAK Inhibitors.

Published in:

Patient Care (Online), 2025, p. 2

By:

Halsey, Grace

Publication type:

Article

Effect and mechanism of PYCR1 on biological function of hepatocellular carcinoma cells under hypoxia.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-03028-7

By:

Guo, Jiayi;
Jin, Xinxin;
Zhang, Junli;
Zhang, Yuming;
Wu, Wenjuan

Publication type:

Article

Connection between circulating inflammatory cytokines and non-small cell lung cancer: integrated Mendelian randomization and gene function analysis.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02817-4

By:

Niu, Ke;
Tang, Jing;
Zhong, Jianxin;
Zheng, Lin;
Zhu, Yayu;
Ling, Huijuan;
Liu, Yu;
Xu, Qing;
Qiu, Ping;
Chen, Liwen

Publication type:

Article

Modulating the JAK/STAT pathway with natural products: potential and challenges in cancer therapy.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02369-7

By:

Nair, Bhagyalakshmi;
Menon, Anjana;
Rithwik Kalidas, M.;
Nath, Lekshmi R.;
Calina, Daniela;
Sharifi-Rad, Javad

Publication type:

Article

Downregulated STAT3 and STAT5B are prognostic biomarkers for colorectal cancer and are associated with immune infiltration.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02085-2

By:

Li, Qier;
Wang, Jingzhi;
Liu, Qingqing;
Gan, Min;
Yan, Jianing;
Yu, Xuan;
Shao, Yongfu

Publication type:

Article

Viral IL-10 can promote the proliferation, migration and invasion of nasopharyngeal carcinoma cells and inhibit their apoptosis.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-01937-1

By:

Qiu, Qin;
Yang, Xingyu;
Li, Xiaojiang;
Ren, Yanxin;
Huang, Ning

Publication type:

Article

广叶绣球菌多糖对小鼠 CD8<sup>+</sup> T 细胞介导的免疫应答调控机制.

Published in:

Mycosystema, 2023, v. 42, n. 5, p. 1163, doi. 10.13346/j.mycosystema.220251

By:

贺楷雄;
程艳芬;
云少君;
程菲儿;
曹谨玲;
冯翠萍

Publication type:

Article

Nicotine-induced activation of cholinergic receptor nicotinic alpha 5 subunit mediates the malignant behaviours of laryngeal squamous epithelial cells by interacting with RABL6.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-02051-x

By:

Shen, Yujie;
Huang, Qiang;
Yuan, Xiaohui;
Gong, Hongli;
Xu, Chengzhi;
Du, Huaidong;
Hsueh, Chi-Yao;
Zhou, Liang

Publication type:

Article

NUP43 promotes PD-L1/nPD-L1/PD-L1 feedback loop via TM4SF1/JAK/STAT3 pathway in colorectal cancer progression and metastatsis.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-02025-z

By:

Wu, Fan;
Sun, Guoqiang;
Nai, Yongjun;
Shi, Xuesong;
Ma, Yong;
Cao, Hongyong

Publication type:

Article

Frozen Shoulder as a Metabolic and Immune Disorder: Potential Roles of Leptin Resistance, JAK-STAT Dysregulation, and Fibrosis.

Published in:

Journal of Clinical Medicine, 2025, v. 14, n. 5, p. 1780, doi. 10.3390/jcm14051780

By:

Navarro-Ledesma, Santiago

Publication type:

Article

Vitiligo: From Pathogenesis to Treatment.

Published in:

Journal of Clinical Medicine, 2024, v. 13, n. 17, p. 5225, doi. 10.3390/jcm13175225

By:

Speeckaert, Reinhart;
Caelenberg, Elise Van;
Belpaire, Arno;
Speeckaert, Marijn M.;
Geel, Nanja van

Publication type:

Article

Is the JAK-STAT Signaling Pathway Involved in the Pathogenesis of Depression?

Published in:

Journal of Clinical Medicine, 2022, v. 11, n. 7, p. 2056, doi. 10.3390/jcm11072056

By:

Gałecka, Małgorzata;
Szemraj, Janusz;
Su, Kuan-Pin;
Halaris, Angelos;
Maes, Michael;
Skiba, Aleksandra;
Gałecki, Piotr;
Bliźniewska-Kowalska, Katarzyna

Publication type:

Article

Antiviral, Immunomodulatory and Antiproliferative Activities of Recombinant Soluble IFNAR2 without IFN-ß Mediation.

Published in:

Journal of Clinical Medicine, 2020, v. 9, n. 4, p. 959, doi. 10.3390/jcm9040959

By:

Hurtado-Guerrero, Isaac;
Hernáez, Bruno;
Pinto-Medel, María J.;
Calonge, Esther;
Rodriguez-Bada, José L.;
Urbaneja, Patricia;
Alonso, Ana;
Mena-Vázquez, Natalia;
Aliaga, Pablo;
Issazadeh-Navikas, Shohreh;
Pavia, José;
Leyva, Laura;
Alcamí, José;
Alcamí, Antonio;
Fernández, Óscar;
Oliver-Martos, Begoña

Publication type:

Article

综合性分析miR-224 在肝癌中的表达及其生物学作用.

Published in:

Chinese Journal of Cancer Biotherapy, 2021, v. 28, n. 2, p. 135, doi. 10.3872/j.issn.1007-385x.2021.02.006

By:

宗彦红;
于芳;
刘义龙;
霍丽静;
唐志鹏;
谭鹤;
帖彦清

Publication type:

Article

Roles of core regulatory noncoding RNAs in bovine Staphylococcus aureus subclinical mastitis.

Published in:

Journal of Animal Science, 2024, v. 102, p. 144, doi. 10.1093/jas/skae234.172

By:

Omonijo, Faith A.;
Mengqi Wang;
Gagné, David;
Laterrière, Mario;
Xin Zhao;
Ibeagha-Awemu, Eveline M.

Publication type:

Article

IGF2BP2 regulates the proliferation and migration of endometrial stromal cells through the PI3K/AKT/mTOR signaling pathway in Hu sheep.

Published in:

Journal of Animal Science, 2024, v. 102, p. 1, doi. 10.1093/jas/skae129

By:

Deng, Kaiping;
Li, Xiaodan;
Liu, Zhipeng;
Su, Yalong;
Sun, Xuan;
Wei, Wurilege;
Fan, Yixuan;
Zhang, Yanli;
Wang, Feng

Publication type:

Article

Identification and characterization of long non-coding RNAs in mammary gland tissues of Chinese Holstein cows.

Published in:

Journal of Animal Science, 2024, v. 102, p. 1, doi. 10.1093/jas/skae128

By:

Wang, Yanru;
Liang, Yan;
Xia, Yuxin;
Wang, Mengqi;
Zhang, Huimin;
Li, Mingxun;
Yang, Zhangping;
Karrow, Niel A;
Mao, Yongjiang

Publication type:

Article

Activation of Multiple Inflammatory Signaling Pathways May Contribute to the Pathogenesis of Idiopathic Cystitis in Felines.

Published in:

Journal of Animal Science, 2023, v. 101, p. 449, doi. 10.1093/jas/skad281.533

By:

Tavener, Selena K.;
Eichman, Rachel A.;
Panickar, Kiran S.

Publication type:

Article

Characterization and functional analyses of a novel chicken CD8a variant X1 (CD8α1).

Published in:

Journal of Animal Science, 2016, v. 94, n. 7, p. 2737, doi. 10.2527/jas.2015-0133

By:

Truong, A. D.;
Ban, J.;
Park, B.;
Hong, Y. H.;
Lillehoj, H. S.

Publication type:

Article

Integrative Multiomics Profiling Unveils the Protective Function of Ulinastatin against Dextran Sulfate Sodium-Induced Colitis.

Published in:

Antioxidants, 2024, v. 13, n. 2, p. 214, doi. 10.3390/antiox13020214

By:

Yu, Tianyu;
Yan, Jun;
Wang, Ruochen;
Zhang, Lei;
Hu, Xiake;
Xu, Jiaxi;
Li, Fanni;
Sun, Qi

Publication type:

Article

Human NCF1 90H Variant Promotes IL-23/IL-17—Dependent Mannan-Induced Psoriasis and Psoriatic Arthritis.

Published in:

Antioxidants, 2023, v. 12, n. 7, p. 1348, doi. 10.3390/antiox12071348

By:

Li, Yanpeng;
Li, Zhilei;
Nandakumar, Kutty Selva;
Holmdahl, Rikard

Publication type:

Article

Lotus Bee Pollen Extract Inhibits Isoproterenol-Induced Hypertrophy via JAK2/STAT3 Signaling Pathway in Rat H9c2 Cells.

Published in:

Antioxidants, 2023, v. 12, n. 1, p. 88, doi. 10.3390/antiox12010088

By:

Han, Shuo;
Chen, Lifu;
Zhang, Yi;
Xie, Shihui;
Yang, Jiali;
Su, Songkun;
Yao, Hong;
Shi, Peiying

Publication type:

Article

Discovery of New Triterpenoids Extracted from Camellia oleifera Seed Cake and the Molecular Mechanism Underlying Their Antitumor Activity.

Published in:

Antioxidants, 2023, v. 12, n. 1, p. 7, doi. 10.3390/antiox12010007

By:

Wu, Zelong;
Tan, Xiaofeng;
Zhou, Junqin;
Yuan, Jun;
Yang, Guliang;
Li, Ze;
Long, Hongxu;
Yi, Yuhang;
Lv, Chenghao;
Zeng, Chaoxi;
Qin, Si

Publication type:

Article

Saikosaponin-d Attenuates Hashimoto's Thyroiditis by Regulating Macrophage Polarization.

Published in:

2022

By:

Du, Peng;
Xu, Jianbin;
Jiang, Yanfei;
Zhao, Jing;
Gao, Chaoqun;
Fang, Yudie;
Yang, Xiaorong;
Yang, Yan-ping;
Zhang, Jin-an

Publication type:

journal article

Hepatocellular carcinoma-derived exosomal miRNA-761 regulates the tumor microenvironment by targeting the SOCS2/JAK2/STAT3 pathway.

Published in:

World Journal of Emergency Medicine, 2022, v. 13, n. 5, p. 379, doi. 10.5847/wjem.j.1920-8642.2022.089

By:

Xiao-hu Zhou;
Hao Xu;
Chang Xu;
Ying-cai Yan;
Lin-shi Zhang;
Qiang Sun;
Wei-lin Wang;
Yan-jun Shi

Publication type:

Article

Bioinformatics-Based Identification of CircRNA-MicroRNA-mRNA Network for Calcific Aortic Valve Disease.

Published in:

Genetics Research, 2023, v. 2023, p. 1, doi. 10.1155/2023/8194338

By:

Song, Linghong;
Wang, Yubing;
Feng, Yufei;
Peng, Hao;
Wang, Chengyan;
Duan, Juncang;
Liu, Kejian;
Shen, Xihua;
Gu, Wenyi;
Qi, Yan;
Jin, Shan;
Pang, Lijuan

Publication type:

Article