Works matching DE "ISOPRENYLATION"

Results: 340

Prenylation of flavonoids by DMATS1 and their anti‐inflammatory activities.

Published in:

Journal of the Science of Food & Agriculture, 2025, v. 105, n. 8, p. 4586, doi. 10.1002/jsfa.14198

By:

Gao, Zhengjiao;
Tang, Dingtao;
He, Bingfeng;
Quan, Jiajie;
Zhang, Zhengke;
Jiang, Yueming;
Yang, Bao;
Yang, Jiali

Publication type:

Article

Regioselective Dehydrogenative Reverse Prenylation of Indoles with 2‐Methyl‐2‐butene.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 37, p. 1, doi. 10.1002/chem.202300933

By:

Li, Yong‐Hua;
Wang, Meng‐Yue;
Zhao, Bao‐Yin;
Zhang, Hong‐Xia;
Guo, Shi‐Huan;
Jia, Qiong;
Wang, Yong‐Qiang

Publication type:

Article

Cover Feature: Residue‐Selective C−H Sulfenylation Enabled by Acid‐Activated S‐Acetamidomethyl Cysteine Sulfoxide with Application to One‐Pot Stapling and Lipidation Sequence (Chem. Eur. J. 26/2023).

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 26, p. 1, doi. 10.1002/chem.202300799

By:

Ohkawachi, Kento;
Anzaki, Kaito;
Kobayashi, Daishiro;
Kyan, Ryuji;
Yasuda, Takuma;
Denda, Masaya;
Harada, Norio;
Shigenaga, Akira;
Inagaki, Nobuya;
Otaka, Akira

Publication type:

Article

Residue‐Selective C−H Sulfenylation Enabled by Acid‐Activated S‐Acetamidomethyl Cysteine Sulfoxide with Application to One‐Pot Stapling and Lipidation Sequence.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 26, p. 1, doi. 10.1002/chem.202300799

By:

Ohkawachi, Kento;
Anzaki, Kaito;
Kobayashi, Daishiro;
Kyan, Ryuji;
Yasuda, Takuma;
Denda, Masaya;
Harada, Norio;
Shigenaga, Akira;
Inagaki, Nobuya;
Otaka, Akira

Publication type:

Article

C‐Terminal Lipidation of SARS‐CoV‐2 Fusion Peptide Reinstates Superior Membrane Fusion Catalytic Ability.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 10, p. 1, doi. 10.1002/chem.202203034

By:

Sardar, Avijit;
Bera, Tapas;
Kumar Samal, Santosh;
Dewangan, Nikesh;
Kamble, Mithila;
Guha, Samit;
Tarafdar, Pradip K.

Publication type:

Article

Berichtigung: Direct Peptide Lipidation through Thiol-Ene Coupling Enables Rapid Synthesis and Evaluation of Self-Adjuvanting Vaccine Candidates.

Published in:

Angewandte Chemie, 2013, v. 125, n. 45, p. 11902, doi. 10.1002/ange.201308276

By:

Wright, Tom H.;
Brooks, Anna E. S.;
Didsbury, Alicia J.;
Williams, Geoffrey M.;
Harris, Paul W. R.;
Dunbar, P. Rod;
Brimble, Margaret A.

Publication type:

Article

Direct Peptide Lipidation through Thiol-Ene Coupling Enables Rapid Synthesis and Evaluation of Self-Adjuvanting Vaccine Candidates.

Published in:

Angewandte Chemie, 2013, v. 125, n. 40, p. 10810, doi. 10.1002/ange.201305620

By:

Wright, Tom H.;
Brooks, Anna E. S.;
Didsbury, Alicia J.;
Williams, Geoffrey M.;
Harris, Paul W. R.;
Dunbar, P. Rod;
Brimble, Margaret A.

Publication type:

Article

Lipidated peptides via post-synthetic thioalkylation promoted by molecular sieves.

Published in:

Amino Acids, 2014, v. 46, n. 8, p. 1899, doi. 10.1007/s00726-014-1742-y

By:

Calce, Enrica;
Leone, Marilisa;
Monfregola, Luca;
De Luca, Stefania

Publication type:

Article

Fluvastatin protects neuronal cells from hydrogen peroxide-induced toxicity with decreasing oxidative damage and increasing PI3K/Akt/mTOR signalling.

Published in:

Journal of Pharmacy & Pharmacology, 2021, v. 73, n. 4, p. 515, doi. 10.1093/jpp/rgaa058

By:

Miaoxia Wang;
Jia Wang;
Meirong Liu;
Gang Chen

Publication type:

Article

ABCA1 haplodeficiency affects the brain transcriptome following traumatic brain injury in mice expressing human APOE isoforms.

Published in:

Acta Neuropathologica Communications, 2018, v. 6, n. 1, p. N.PAG, doi. 10.1186/s40478-018-0569-2

By:

Castranio, Emilie L.;
Wolfe, Cody M.;
Nam, Kyong Nyon;
Letronne, Florent;
Fitz, Nicholas F.;
Lefterov, Iliya;
Koldamova, Radosveta

Publication type:

Article

A Practical Synthetic Route to Artepillin C and Drupanin.

Published in:

Asian Journal of Organic Chemistry, 2021, v. 10, n. 7, p. 1691, doi. 10.1002/ajoc.202100262

By:

Zhao, Xue‐Zheng;
Wang, Lu;
Li, Xiao‐Ya;
Zhang, Qing‐Qing;
Li, Wei;
Lin, Ai‐Jun;
Xu, Jin‐Yi;
Wu, Xiao‐Ming;
Xie, Wei‐Jia

Publication type:

Article

Myristoyl's dual role in allosterically regulating and localizing Abl kinase.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.85216

By:

de Buhr, Svenja;
Gräter, Frauke

Publication type:

Article

Scientific Opinion on the safety and efficacy of vitamin K3 (menadione sodium bisulphite and menadione nicotinamide bisulphite) as a feed additive for all animal species.

Published in:: EFSA Journal, 2014, v. 12, n. 1, p. 1, doi. 10.2903/j.efsa.2014.3532
Publication type:: Article

The Loss of Expression of a Single Type 3 Effector (CT622) Strongly Reduces <italic>Chlamydia trachomatis</italic> Infectivity and Growth.

Published in:

Frontiers in Cellular & Infection Microbiology, 2018, v. 8, p. N.PAG, doi. 10.3389/fcimb.2018.00145

By:

Cossé, Mathilde M.;
Barta, Michael L.;
Fisher, Derek J.;
Oesterlin, Lena K.;
Niragire, Béatrice;
Perrinet, Stéphanie;
Millot, Gaël A.;
Hefty, P. Scott;
Subtil, Agathe

Publication type:

Article

Geranylgeranylation signals to the Hippo pathway for breast cancer cell proliferation and migration.

Published in:

Oncogene, 2015, v. 34, n. 24, p. 3095, doi. 10.1038/onc.2014.251

By:

Mi, W;
Lin, Q;
Childress, C;
Sudol, M;
Robishaw, J;
Berlot, C H;
Shabahang, M;
Yang, W

Publication type:

Article

Prenylcysteine oxidase 1 like protein is required for neutrophil bactericidal activities.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-38447-z

By:

Petenkova, Anastasiia;
Auger, Shelby A.;
Lamb, Jeffrey;
Quellier, Daisy;
Carter, Cody;
To, On Tak;
Milosevic, Jelena;
Barghout, Rana;
Kugadas, Abirami;
Lu, Xiaoxiao;
Geddes-McAlister, Jennifer;
Fichorova, Raina;
Sykes, David B.;
Distefano, Mark D.;
Gadjeva, Mihaela

Publication type:

Article

Unveiling an indole alkaloid diketopiperazine biosynthetic pathway that features a unique stereoisomerase and multifunctional methyltransferase.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-38168-3

By:

Deletti, Garrett;
Green, Sajan D.;
Weber, Caleb;
Patterson, Kristen N.;
Joshi, Swapnil S.;
Khopade, Tushar M.;
Coban, Mathew;
Veek-Wilson, James;
Caulfield, Thomas R.;
Viswanathan, Rajesh;
Lane, Amy L.

Publication type:

Article

Porphyromonas gingivalis traffics into endoplasmic reticulum-rich-autophagosomes for successful survival in human gingival epithelial cells.

Published in:

Virulence, 2018, v. 9, n. 1, p. 845, doi. 10.1080/21505594.2018.1454171

By:

Lee, Kyulim;
Roberts, JoAnn S.;
Choi, Chul Hee;
Atanasova, Kalina R.;
Yilmaz, Özlem

Publication type:

Article

The Aspergillus fumigatus farnesyltransferase Ś-subunit, RamA, mediates growth, virulence, and antifungal susceptibility.

Published in:

Virulence, 2017, v. 8, n. 7, p. 1401, doi. 10.1080/21505594.2017.1328343

By:

Norton, Tiffany S.;
Al Abdallah, Qusai;
Hill, Amy M.;
Lovingood, Rachel V.;
Fortwendel, Jarrod R.

Publication type:

Article

Targeting protein localization for anti-infective therapy.

Published in:

2017

By:

Alspaugh, J. Andrew

Publication type:

Science Experiment

A highly sensitive prenylation assay reveals in vivo effects of bisphosphonate drug on the Rab prenylome of macrophages outside the skeleton.

Published in:

Small GTPases, 2015, v. 6, n. 4, p. 202, doi. 10.1080/21541248.2015.1085485

By:

Ali, Naveid;
Jurczyluk, Julie;
Shay, Gemma;
Tnimov, Zakir;
Alexandrov, Kirill;
Munoz, Marcia A;
Skinner, Oliver P;
Pavlos, Nathan J;
Rogers, Michael J

Publication type:

Article

Flip-Flopping Retinal in Microbial Rhodopsins as a Template for a Farnesyl/Prenyl Flip-Flop Model in Eukaryote GPCRs.

Published in:

Frontiers in Neuroscience, 2019, p. N.PAG, doi. 10.3389/fnins.2019.00465

By:

De Loof, Arnold;
Schoofs, Liliane

Publication type:

Article

Prenyltransferase gene expression reveals an essential role of prenylation for the inflammatory response in human gingival fibroblasts.

Published in:

Journal of Periodontology, 2023, v. 94, n. 12, p. 1450, doi. 10.1002/JPER.23-0220

By:

Diehl, Daniel;
Friedmann, Anton;
Bachmann, Hagen S.

Publication type:

Article

Cardiac decompensation and promiscuous prenylation of small GTPases in cardiomyocytes in response to local mevalonate pathway disruption†.

Published in:

Journal of Pathology, 2022, v. 256, n. 3, p. 249, doi. 10.1002/path.5837

By:

Essandoh, Kobina;
Auchus, Richard J;
Brody, Matthew J

Publication type:

Article

The role of protein modifications in senescence of freeze-dried Acetobacter senegalensis during storage.

Published in:

Microbial Cell Factories, 2014, v. 13, n. 1, p. 1, doi. 10.1186/1475-2859-13-26

By:

Shafiei, Rasoul;
Zarmehrkhorshid, Raziyeh;
Bentaib, Azeddine;
Babanezhad, Manoochehr;
Leprince, Pierre;
Delvigne, Frank;
Thonart, Philippe

Publication type:

Article

Dapper1 promotes autophagy by enhancing the Beclin1-Vps34-Atg14L complex formation.

Published in:

Cell Research, 2014, v. 24, n. 8, p. 912, doi. 10.1038/cr.2014.84

By:

Ma, Benyu;
Cao, Weipeng;
Li, Wenxia;
Gao, Chan;
Qi, Zhen;
Zhao, Yan;
Du, Jun;
Xue, Hua;
Peng, Junya;
Wen, Jun;
Chen, Hua;
Ning, Yuanheng;
Huang, Lei;
Zhang, Hong;
Gao, Xiang;
Yu, Li;
Chen, Ye-Guang

Publication type:

Article

TBK1 is part of a galectin 8 dependent membrane damage recognition complex and drives autophagy upon Adenovirus endosomal escape.

Published in:

PLoS Pathogens, 2022, v. 18, n. 7, p. 1, doi. 10.1371/journal.ppat.1010736

By:

Pied, Noémie;
Daussy, Coralie F.;
Denis, Zoé;
Ragues, Jessica;
Faure, Muriel;
Iggo, Richard;
Tschan, Mario P.;
Roger, Benoit;
Rayne, Fabienne;
Wodrich, Harald

Publication type:

Article

Chemical modification of neuropeptide Y for human Y1 receptor targeting in health and disease.

Published in:

Biological Chemistry, 2019, v. 400, n. 3, p. 299, doi. 10.1515/hsz-2018-0364

By:

Hofmann, Sven;
Bellmann-Sickert, Kathrin;
Beck-Sickinger, Annette G.

Publication type:

Article

Influence of isoform-specific Ras lipidation motifs on protein partitioning and dynamics in model membrane systems of various complexity.

Published in:

Biological Chemistry, 2017, v. 398, n. 5/6, p. 547, doi. 10.1515/hsz-2016-0289

By:

Erwin, Nelli;
Patra, Satyajit;
Dwivedi, Mridula;
Weise, Katrin;
Winter, Roland

Publication type:

Article

Identification of critical residues for the catalytic activity of ComQ, a Bacillus prenylation enzyme for quorum sensing, by using a simple bioassay system.

Published in:

Bioscience, Biotechnology & Biochemistry, 2020, v. 84, n. 2, p. 347, doi. 10.1080/09168451.2019.1685371

By:

Hirooka, Kazutake;
Shioda, Saki;
Okada, Masahiro

Publication type:

Article

A region corresponding to second aspartate-rich motif in tryptophan isoprenylating enzyme, ComQ, serves as a substrate-binding site.

Published in:

Bioscience, Biotechnology & Biochemistry, 2014, v. 78, n. 4, p. 550, doi. 10.1080/09168451.2014.891932

By:

Masahiro Okada;
Ayako Ishihara;
Risa Yamasaki;
Furaitada Tsuji;
Shunsuke Hayashi;
Syohei Usami;
Youji Sakagami

Publication type:

Article

Mosaic Interdigitated Structure in Nanoparticle-Templated Phospholipid Bilayer Supports Partial Lipidation of Apolipoprotein A-I.

Published in:

Particle & Particle Systems Characterization, 2016, v. 33, n. 6, p. 300, doi. 10.1002/ppsc.201600032

By:

Sun, Wangqiang;
Wu, Weiqiang;
McMahon, Kaylin M.;
Rink, Jonathan S.;
Thaxton, C. Shad

Publication type:

Article

Geranylgeranyltransferase I regulates HIF-1α promoting glioblastoma cell migration and invasion.

Published in:

Journal of Neuro-Oncology, 2013, v. 112, n. 3, p. 365, doi. 10.1007/s11060-013-1081-y

By:

Zhou, Xiuping;
Liu, Zhi;
Shi, Qiong;
Jiao, Jiantong;
Bian, Wenbin;
Song, Xu;
Mo, Jianbing;
sang, Ben;
Xu, Yinfu;
Qian, Jinming;
Chao, Yuewen;
Yu, Rutong

Publication type:

Article

Towards an Improvement of Anticancer Activity of Benzyl Adenosine Analogs.

Published in:

Molecules, 2021, v. 26, n. 23, p. 7146, doi. 10.3390/molecules26237146

By:

Covelli, Verdiana;
Grimaldi, Manuela;
Randino, Rosario;
Firoznezhad, Mohammad;
Proto, Maria Chiara;
Simone, Veronica De;
Matteoli, Gianluca;
Gazzerro, Patrizia;
Bifulco, Maurizio;
D'Ursi, Anna Maria;
Rodriquez, Manuela

Publication type:

Article

Synthesis and Characterization of Bone Binding Antibiotic-1 (BBA-1), a Novel Antimicrobial for Orthopedic Applications.

Published in:

Molecules, 2021, v. 26, n. 6, p. 1541, doi. 10.3390/molecules26061541

By:

Kamble, Sumedh;
Valtchev, Peter;
Dao, Aiken;
Pelras, Théophile;
Rogers, Michael J;
Savage, Paul B.;
Dehghani, Fariba;
Schindeler, Aaron;
Barrajon, Enrique

Publication type:

Article

C7-Prenylation of Tryptophan-Containing Cyclic Dipeptides by 7-Dimethylallyl Tryptophan Synthase Significantly Increases the Anticancer and Antimicrobial Activities.

Published in:

Molecules, 2020, v. 25, n. 16, p. 3676, doi. 10.3390/molecules25163676

By:

Liu, Rui;
Zhang, Hongchi;
Wu, Weiqiang;
Li, Hui;
An, Zhipeng;
Zhou, Feng

Publication type:

Article

Synthesis of Lactam-Bridged and Lipidated Cyclo-Peptides as Promising Anti-Phytopathogenic Agents.

Published in:

Molecules, 2020, v. 25, n. 4, p. 811, doi. 10.3390/molecules25040811

By:

Vasco, Aldrin V.;
Brode, Martina;
Méndez, Yanira;
Valdés, Oscar;
Rivera, Daniel G.;
Wessjohann, Ludger A.;
Dömling, Alexander;
Shaabani, Shabnam

Publication type:

Article

The Antioxidant Activity of Prenylflavonoids.

Published in:

Molecules, 2020, v. 25, n. 3, p. 696, doi. 10.3390/molecules25030696

By:

Santos, Clementina M. M.;
Silva, Artur M. S.

Publication type:

Article

Microbial Transformation of Prenylquercetins by Mucor hiemalis.

Published in:

Molecules, 2020, v. 25, n. 3, p. 528, doi. 10.3390/molecules25030528

By:

Han, Fubo;
Xiao, Yina;
Lee, Ik-Soo;
Ward, Jane

Publication type:

Article

Protein Prenylation in Plant Stress Responses.

Published in:

Molecules, 2019, v. 24, n. 21, p. 3906, doi. 10.3390/molecules24213906

By:

Hála, Michal;
Žárský, Viktor;
Swiezewska, Ewa;
Surmacz, Liliana

Publication type:

Article

Arginine in the FARM and SARM: A Role in Chain-Length Determination for Arginine in the Aspartate-Rich Motifs of Isoprenyl Diphosphate Synthases from Mycobacterium tuberculosis†.

Published in:

Molecules, 2018, v. 23, n. 10, p. 2546, doi. 10.3390/molecules23102546

By:

Nagel, Raimund;
Thomas, Jill A.;
Adekunle, Faith A.;
Mann, Francis M.;
Peters, Reuben J.;
Zhou, Wenxu

Publication type:

Article

Four Prenylflavone Derivatives with Antiplasmodial Activities from the Stem of Tephrosia purpurea subsp. leptostachya.

Published in:

Molecules, 2017, v. 22, n. 9, p. 1514, doi. 10.3390/molecules22091514

By:

Atilaw, Yoseph;
Muiva-Mutisya, Lois;
Ndakala, Albert;
Akala, Hoseah M.;
Yeda, Redemptah;
Yu J. Wu;
Coghi, Paolo;
Wong, Vincent K. W.;
Erdélyi, Máté;
Yenesew, Abiy

Publication type:

Article

Three New Isoprenylated Flavonoids from the Root Bark of Morus alba.

Published in:

Molecules, 2016, v. 21, n. 9, p. 1112, doi. 10.3390/molecules21091112

By:

Jae-Woo Jung;
Ji-Hae Park;
Yeong-Geun Lee;
Kyeong-Hwa Seo;
Eun-Ji Oh;
Dae-Young Lee;
Dong-Wook Lim;
Daeseok Han;
Nam-In Baek

Publication type:

Article

Prenylation of aromatic amino acids and plant phenolics by an aromatic prenyltransferase from Rasamsonia emersonii.

Published in:

Applied Microbiology & Biotechnology, 2024, v. 108, n. 1, p. 1, doi. 10.1007/s00253-024-13254-8

By:

Chunkrua, Pimvisuth;
Leschonski, Kai P.;
Gran‐Scheuch, Alejandro A.;
Vreeke, Gijs J. C.;
Vincken, Jean-Paul;
Fraaije, Marco W.;
van Berkel, Willem J. H.;
de Bruijn, Wouter J. C.;
Kabel, Mirjam A.

Publication type:

Article

Biochemical characterization of a multiple prenyltransferase from Tolypocladium inflatum.

Published in:

Applied Microbiology & Biotechnology, 2024, v. 108, n. 1, p. 1, doi. 10.1007/s00253-024-13113-6

By:

Han, Haiyan;
Peng, Shuang;
Wang, Qian;
Wang, Hongwei;
Wang, Pengchao;
Li, Chang;
Qi, Jianzhao;
Liu, Chengwei

Publication type:

Article

Synthesis of structural analogues of GGT1-DU40, a potent GGTase-1 inhibitor.

Published in:

Zeitschrift für Naturforschung B: A Journal of Chemical Sciences, 2016, v. 71, n. 4, p. 333, doi. 10.1515/znb-2016-0019

By:

Mansha, Muhammad;
Ullah, Nisar;
Alhooshani, Khalid

Publication type:

Article

Critical role for isoprenoids in apicoplast biogenesis by malaria parasites.

Published in:

eLife, 2022, p. 1, doi. 10.7554/eLife.73208

By:

Okada, Megan;
Rajaram, Krithika;
Swift, Russell P.;
Mixon, Amanda;
Maschek, John Alan;
Prigge, Sean T.;
Sigala, Paul A.

Publication type:

Article

Structural basis for membrane recruitment of ATG16L1 by WIPI2 in autophagy.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.70372

By:

Strong, Lisa M.;
Chunmei Chang;
Riley, Julia F.;
Boecker, C. Alexander;
Flower, Thomas G.;
Buffalo, Cosmo Z.;
Xuefeng Ren;
Stavoe, Andrea K. H.;
Holzbaur, Erika L. F.;
Hurley, James H.

Publication type:

Article

Metabolic labeling with an alkyne probe reveals similarities and differences in the prenylomes of several brain-derived cell lines and primary cells.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-83666-3

By:

Suazo, Kiall F.;
Jeong, Angela;
Ahmadi, Mina;
Brown, Caroline;
Qu, Wenhui;
Li, Ling;
Distefano, Mark D.

Publication type:

Article

ATG12-ATG3 interacts with Alix to promote basal autophagic flux and late endosome function.

Published in:

Nature Cell Biology, 2015, v. 17, n. 3, p. 300, doi. 10.1038/ncb3112

By:

Murrow, Lyndsay;
Malhotra, Ritu;
Debnath, Jayanta

Publication type:

Article