Works about IRON overload

Results: 1137

Relationship Between Hepatic Iron Concentration and Glycemic Metabolism, Prediabetes, and Type 2 Diabetes: A Systematic Review.

Published in:

Nutrition Reviews, 2025, v. 83, n. 7, p. e1828, doi. 10.1093/nutrit/nuae197

By:

Kirkutyte, Indre;
Latunde-Dada, Gladys Oluyemisi

Publication type:

Article

Targeting the ferroptosis pathway for rheumatoid arthritis: molecular mechanisms and prospects for inhibitor development.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1610121

By:

Wang, Zhuoling;
Bai, Xinyue;
Zhang, Huahua;
Yang, Min;
Liu, Meilin;
Nie, Tingyu;
Li, Tianjiao;
Zhang, Mingru;
Wang, Xingdan;
Wang, Jin;
Han, Jiming;
Liu, Xiaolong

Publication type:

Article

Evaluating Renal Glomerular Function in Beta-Thalassemia Patients Receiving Deferasirox Using Serum Cystatin-C and Creatinine: A Cross-Sectional Study.

Published in:

Hemoglobin, 2025, v. 49, n. 3, p. 178, doi. 10.1080/03630269.2025.2497856

By:

Akbarnataj, Hossein;
Eghbali, Aziz;
Ashayeri, Neda;
Padooiy Nooshabadi, Mohammadreza;
Hosseini Shamsabadi, Rozita

Publication type:

Article

Hepatobiliary Manifestations in Thalassemia Patients: A Narrative Review.

Published in:

Hemoglobin, 2025, v. 49, n. 3, p. 200, doi. 10.1080/03630269.2025.2493946

By:

Tiwari, Asha;
Rao, Ekta;
Suresh, Iswarya;
Tiwari, Manish;
Kumar, Ravindra

Publication type:

Article

FRRS1L variants and ferriheme overload drive hyperpigmentation and systemic Iron overload in lanping black bone sheep.

Published in:

Cell & Bioscience, 2025, v. 15, n. 1, p. 1, doi. 10.1186/s13578-025-01426-6

By:

Han, Deping;
Zhang, Yuanyuan;
Deng, Weidong;
Yang, Xue;
Chen, Jianfei;
Hua, Guoying;
Darwish, Hesham Y.A.;
Mao, Huaming;
Gou, Xiao;
Wang, Jiankui;
Cui, Kai;
Ma, Yuhao;
Tai, Yurong;
Dong, Xianggui;
Yao, Yanzhu;
Yang, Zu;
Cao, Suying;
Yu, Zhengquan;
Liu, Wansheng;
Deng, Xuemei

Publication type:

Article

Hepatic and cardiac iron overload quantified by magnetic resonance imaging in patients on hemodialysis: A systematic review and meta‐analysis.

Published in:

Hemodialysis International, 2023, v. 27, n. 1, p. 3, doi. 10.1111/hdi.13054

By:

Nashwan, Abdulqadir J.;
Yassin, Mohamed A.;
Abd‐Alrazaq, Alaa;
Shuweihdi, Farag;
Othman, Muftah;
Abdul Rahim, Hanan F.;
Shraim, Mujahed

Publication type:

Article

Therapeutic modalities of deferiprone in Parkinson's disease: SKY and EMBARK studies.

Published in:

Journal of Parkinson's Disease, 2025, v. 15, n. 1, p. 72, doi. 10.1177/1877718X241300295

By:

Devos, David;
Rascol, Olivier;
Meissner, Wassilios G;
Foubert-Samier, Alexandra;
Lewis, Simon;
Tranchant, Christine;
Anheim, Mathieu;
Maltête, David;
Remy, Philippe;
Eggert, Karla;
Pape, Heidi;
Geny, Christian;
Couratier, Philippe;
Carroll, Camille;
Sheridan, Ray;
Burn, David;
Pavese, Nicola;
Raw, Jason;
Berg, Daniela;
Suchowersky, Oksana

Publication type:

Article

Hereditary Red Blood Cell Enzymopathies.

Published in:

Journal of Pediatric Academy (J. Pediatr. Acad.), 2021, v. 2, n. 1, p. 9, doi. 10.51271/jpea-2021-0120

By:

Aksu, Tekin

Publication type:

Article

Exploring Ferroptosis in Allergic Inflammatory Diseases: Emerging Mechanisms and Therapeutic Perspectives.

Published in:

Cell Biology International, 2025, v. 49, n. 7, p. 739, doi. 10.1002/cbin.70026

By:

Sutanto, Henry;
Pratiwi, Laras;
Fetarayani, Deasy

Publication type:

Article

Study the Adverse Impact of Iron Overload on Growth-related Functions of the Pituitary and Thyroid Glands in Iraqi Patients with Hemoglobinopathies.

Published in:

Journal of Applied Hematology, 2025, v. 16, n. 2, p. 145, doi. 10.4103/joah.joah_26_25

By:

Abbas, Hamid Jaddoa;
Salem, Wisal Abdulrhman;
Majeed, Rana Hassan Abdul;
Al-Shawi, Ali A. A.

Publication type:

Article

Associations between Serum Ferritin Levels, Age-stratified Hematological Parameters, and Hemoglobin A<sub>2</sub> Levels in Iraqi Beta Thalassemia Carriers.

Published in:

Journal of Applied Hematology, 2025, v. 16, n. 2, p. 111, doi. 10.4103/joah.joah_49_25

By:

Al-Maaroof, Zainab W.;
Sharifi, Liqaa Mohammed Al

Publication type:

Article

Rhinoceromics: a multi-amplicon study with clinical markers to transferrin saturation levels in ex-situ black rhinoceros (Diceros bicornis michaeli).

Published in:

Frontiers in Microbiology, 2025, p. 1, doi. 10.3389/fmicb.2025.1515939

By:

Bruins-van Sonsbeek, Linda G. R.;
Verschuren, Martie C. M.;
Kaal, Sonja;
Lindenburg, Peter W.;
Rodenburg, Kees W.;
Clauss, Marcus;
Speksnijder, Arjen G. C. L.;
Rutten, Victor P.M.G.;
Bonnet, Bas F. J.;
Wittink, Floyd

Publication type:

Article

Genotype Distribution and Clinical Characteristics of Thalassemia Patients Needing Transfusion in Yangjiang, Western Guangdong.

Published in:

Transfusion Medicine & Hemotherapy, 2025, v. 52, n. 3, p. 202, doi. 10.1159/000540518

By:

Chen, Zhi-Xiao;
Liu, Rong-Huo;
Huang, Jian-Cheng;
Mo, Jia-Min;
Zeng, Yan-Qing;
Huang, Yu-Chan;
Yang, Li-Ye

Publication type:

Article

The hook osteophyte (sign) in hereditary haemochromatosis.

Published in:

2025

By:

Jawad, Noor;
Jawad, Ali

Publication type:

Letter

Genome mining based on transcriptional regulatory networks uncovers a novel locus involved in desferrioxamine biosynthesis.

Published in:

PLoS Biology, 2025, v. 23, n. 6, p. 1, doi. 10.1371/journal.pbio.3003183

By:

Augustijn, Hannah E.;
Reitz, Zachary L.;
Zhang, Le;
Boot, Jeanine A.;
Elsayed, Somayah S.;
Challis, Gregory L.;
Medema, Marnix H.;
van Wezel, Gilles P.

Publication type:

Article

Iron-Mediated Overexpression of Amyloid Precursor Protein via Iron Responsive mRNA in Alzheimer's Disease.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 11, p. 5283, doi. 10.3390/ijms26115283

By:

Khan, Mateen A.

Publication type:

Article

Astilbin Alleviates IL-17-Induced Hyperproliferation and Inflammation in HaCaT Cells via Inhibiting Ferroptosis Through the cGAS-STING Pathway.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 11, p. 5075, doi. 10.3390/ijms26115075

By:

Xu, Xiaohan;
Zhang, Huizhong;
Chang, Aqian;
Peng, Hulinyue;
Li, Shiman;
Zhang, Ke;
Wang, Wenqi;
Yin, Xingbin;
Qu, Changhai;
Dong, Xiaoxv;
Ni, Jian

Publication type:

Article

Correlation of Fibro-scan with liver biopsy to assess Iron Overload in Beta Thalassemia Major patients undergoing bone marrow transplant.

Published in:

Isra Medical Journal, 2024, v. 16, n. 2, p. 42, doi. 10.55282/imj.oa1422

By:

Rahim, Uzma;
Ali, Muhammad Zeeshan;
Iftikhar, Raheel;
Khattak, Tariq Azam;
Khan, Hashim;
Afzal, Muhammad

Publication type:

Article

Endothelial cell iron overload and ferroptosis mediate thrombosis and inflammation through the miR-32-5p/neurofibromin 2 pathway.

Published in:

European Journal of Medical Research, 2025, v. 30, n. 1, p. 1, doi. 10.1186/s40001-025-02716-y

By:

Deng, Ying;
Lin, Xueguang;
Wei, Jun;
Chen, Bo;
Yan, Huafang;
Wang, Bo;
Li, Jialong;
Zhao, Yuqun;
Yu, Bo;
Tang, Jingdong;
Jiang, Shuai

Publication type:

Article

Efficacy of Gandhakadi Yoga and Sharapunkha Vati as an add on to standard-of-care in the management of thalassemia major (Beejadushtijanya Pandu) in children – A randomized controlled clinical trial.

Published in:

AYU: An International Quarterly Journal of Research in Ayurveda, 2024, v. 45, n. 4, p. 212, doi. 10.4103/ayu.ayu_277_23

By:

Chaudhary, Naresh B.;
Kori, Virendra Kumar;
Bhinde, Sagar M.;
Shah, Sonal P.

Publication type:

Article

Protective Effects of Eugenol Against Iron Overload-induced Nephrotoxicity in Male Rats.

Published in:

Iranian Journal of Veterinary Medicine, 2025, v. 19, n. 2, p. 341, doi. 10.32598/ijvm.19.3.1005540

By:

Malik Al-Mashhadi, Ahmed M.;
Al-Sharafi, Nabeel Mohammed

Publication type:

Article

Unveiling the Hidden Dangers of Iron Overload - A Comprehensive Literature Review.

Published in:

International Journal of High School Research, 2025, v. 7, n. 5, p. 89, doi. 10.36838/v7i5.13

By:

Eke, Selim

Publication type:

Article

Comparative analysis of mortality patterns and treatment strategies in thalassaemia and sickle cell disease patients: A 12‐year study.

Published in:

British Journal of Haematology, 2025, v. 206, n. 5, p. 1466, doi. 10.1111/bjh.20043

By:

Delicou, Sophia;
Manganas, Konstantinos;
Diamantidis, Michael D.;
Venou, Theodora Maria;
Delaporta, Polyxeni;
Pantelidou, Despoina;
Spachiou, Eirini;
Tsagia, Sofia;
Pappi, Vasiliki;
Petropoulou, Foteini;
Kapsali, Eleni;
Evliati, Loukia;
Papaioannou, Konstantina;
Katsatou, Marianna;
Klironomos, Evangelos;
Vasiliadi, Artemis;
Gkoutzouvelidis, Angelos;
Giasari, Panagiota;
Zisis, Christos;
Lafiatis, Ioannis

Publication type:

Article

Hepatic ferroptosis induced by Clonorchis sinensis exacerbates liver fibrosis.

Published in:

PLoS Neglected Tropical Diseases, 2025, v. 19, n. 6, p. 1, doi. 10.1371/journal.pntd.0013164

By:

Zhang, Haoyang;
Wang, Xiaocen;
Zhang, Xu;
Ma, Yeting;
Bao, Penglin;
Yu, Yanhui;
Wang, Yuru;
Gong, Pengtao;
Zhang, Nan;
Lee, Soon-Ok;
Li, Xin;
Li, Jianhua

Publication type:

Article

Alpinetin protects against iron overload related osteoarthritis via NRF2/HO-1 pathway.

Published in:

PLoS ONE, 2025, v. 20, n. 6, p. 1, doi. 10.1371/journal.pone.0317930

By:

Cai, Dongling;
Pan, Zhaofeng;
Li, Shaocong;
He, Qi;
Chen, Baihao;
Li, Miao;
Xiao, Jiacong;
Wan, Fancheng;
Wang, Haibin;
Zhou, Chi

Publication type:

Article

The Ferroptosis–Mitochondrial Axis in Depression: Unraveling the Feedforward Loop of Oxidative Stress, Metabolic Homeostasis Dysregulation, and Neuroinflammation.

Published in:

Antioxidants, 2025, v. 14, n. 5, p. 613, doi. 10.3390/antiox14050613

By:

Liu, Xu;
Luo, Qiang;
Zhao, Yulong;
Ren, Peng;
Jin, Yu;
Zhou, Junjie

Publication type:

Article

Vitamin C Inhibits Scale Drop Disease Virus Infectivity by Targeting Nrf2 to Reduce Ferroptosis.

Published in:

Antioxidants, 2025, v. 14, n. 5, p. 576, doi. 10.3390/antiox14050576

By:

Chen, Jiaming;
Fu, Yuting;
Weng, Shaoping;
He, Jianguo;
Dong, Chuanfu

Publication type:

Article

Hydrogen Sulfide (H 2 S) Metabolism, Iron Overload, and Apoptosis–Autophagy Equilibrium in Vascular Smooth Muscle Cells.

Published in:

Antioxidants, 2025, v. 14, n. 5, p. 560, doi. 10.3390/antiox14050560

By:

Arif, Hassan Mustafa;
Fu, Ming;
Wang, Rui

Publication type:

Article

Curcumin Nanocarriers in the Protection Against Iron- and Alcohol-Induced Oxidative Stress in a Cellular Model of Liver Disease.

Published in:

Biology (2079-7737), 2025, v. 14, n. 5, p. 455, doi. 10.3390/biology14050455

By:

Petagine, Lucy;
Zariwala, Mohammed G.;
Somavarapu, Satyanarayana;
Chan, Stefanie Ho Yi;
Patel, Vinood B.

Publication type:

Article

Hepcidin Deficiency Disrupts Iron Homeostasis and Induces Ferroptosis in Zebrafish Liver.

Published in:

Fishes (MDPI AG), 2025, v. 10, n. 5, p. 243, doi. 10.3390/fishes10050243

By:

Liu, Mingli;
Peng, Mingjian;
Ma, Jingwen;
Hu, Ruiqin;
Xu, Qianghua;
Hu, Peng;
Chen, Liangbiao

Publication type:

Article

Salidroside can protect against ferroptosis in cardiomyocytes and may be related to the regulation of GGT1.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1580506

By:

Feng, Tianhang;
Shi, Jing;
Zhao, Jinghua;
Zhao, Qin;
Wang, Tao;
Wan, Sha;
Fan, Chen;
Wang, Sijia;
Lai, Chunyou;
Yao, Yutong

Publication type:

Article

Expression of salivary hepcidin and its inducer, interleukin 6 as well as type I interferons are significantly elevated in infants with poor oral rotavirus vaccine take in South Africa.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2025.1517893

By:

Mabasa, Vusumuzi;
Seheri, Mapeseka L.;
Magwira, Cliff A.

Publication type:

Article

Proteomics-Based Exploration of the Hepatoprotective Mechanism of α-Lipoic Acid in Rats with Iron Overload-Induced Liver Injury.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4774, doi. 10.3390/ijms26104774

By:

Jiang, Shuxia;
Shu, Yujia;
Guo, Shihui;
Ni, Yingdong;
Zhao, Ruqian;
Shan, Hongli;
Ma, Wenqiang

Publication type:

Article

Excessive iron accumulation in the striatum associated with addictive behaviors of medication-overuse headache: a prospective study.

Published in:

BMC Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12916-025-04125-8

By:

Pei, Xun;
Bai, Xiaoyan;
Zhang, Xue;
Hu, Zhangxuan;
Wang, Wei;
Zhang, Xueyan;
Zhang, Yingkui;
Tang, Hefei;
Zhang, Yaqing;
Yu, Xueying;
Yuan, Ziyu;
Zhang, Peng;
Chen, Tong;
Zhao, Yuanbin;
Jia, Xiuqin;
Yang, Qi;
Wang, Yonggang;
Sui, Binbin

Publication type:

Article

Iron responsive elements mRNA regulate Alzheimer's amyloid precursor protein translation through iron sensing.

Published in:

Frontiers in Aging Neuroscience, 2025, p. 1, doi. 10.3389/fnagi.2025.1483913

By:

Khan, Mateen A.

Publication type:

Article

Molecular mechanisms of alcohol-associated liver disease-ferroptosis and autophagy crosstalk.

Published in:

Molecular Biology Reports, 2025, v. 52, n. 1, p. 1, doi. 10.1007/s11033-025-10443-0

By:

Wang, Yangyang;
Zhou, Xin;
Chen, Hui;
Li, Zhi

Publication type:

Article

The role of ferroptosis in DM-induced liver injury.

Published in:

BioMetals, 2024, v. 37, n. 5, p. 1191, doi. 10.1007/s10534-024-00600-6

By:

Wu, Keping;
Chen, Jiasi;
Lin, Jiawen;
Zhu, Enyi;
Xu, Xiaochang;
Yan, Xiuhong;
Ju, Lang;
Huang, Mingcheng;
Zhang, Yimin

Publication type:

Article

Investigation of the mutual crosstalk between ER stress and PI3K/AKT/mTOR signaling pathway in iron overload-induced liver injury in chicks.

Published in:

BioMetals, 2024, v. 37, n. 4, p. 955, doi. 10.1007/s10534-024-00588-z

By:

Lv, Xiang-Long;
Li, Wen-Lei;
Sun, Feng-Jiao;
An, Yu-Zhi;
Sun, Ning;
Lv, Xiao-Ping;
Gao, Xue-Li

Publication type:

Article

Animal models of kidney iron overload and ferroptosis: a review of the literature.

Published in:

BioMetals, 2023, v. 36, n. 6, p. 1173, doi. 10.1007/s10534-023-00518-5

By:

Ríos-Silva, Mónica;
Cárdenas, Yolitzy;
Ortega-Macías, Alan Gabriel;
Trujillo, Xóchitl;
Murillo-Zamora, Efrén;
Mendoza-Cano, Oliver;
Bricio-Barrios, Jaime Alberto;
Ibarra, Isabel;
Huerta, Miguel

Publication type:

Article

Tip60/Kat5 may be a novel candidate histone acetyltransferase for the regulation of liver iron localization via acetylation.

Published in:

BioMetals, 2022, v. 35, n. 6, p. 1187, doi. 10.1007/s10534-022-00435-z

By:

Baltacı, Nurdan Gönül;
Toraman, Emine;
Akyüz, Mesut;
Kalın, Şeyda Nur;
Budak, Harun

Publication type:

Article

Iron overload impairs renal function and is associated with vascular calcification in rat aorta.

Published in:

BioMetals, 2022, v. 35, n. 6, p. 1325, doi. 10.1007/s10534-022-00449-7

By:

Song, Yanqiu;
Yang, Ning;
Si, Hailong;
Liu, Ting;
Wang, Hongyu;
Geng, Hua;
Qin, Qin;
Guo, Zhigang

Publication type:

Article

Effects of acute iron overload on Nrf2-related glutathione metabolism in rat brain.

Published in:

BioMetals, 2021, v. 34, n. 5, p. 1017, doi. 10.1007/s10534-021-00324-x

By:

Piloni, Natacha E.;
Vargas, Romina;
Fernández, Virginia;
Videla, Luis A.;
Puntarulo, Susana

Publication type:

Article

Prediction of MRI R2*$$ {\mathrm{R}}_2^{\ast } $$ relaxometry in the presence of hepatic steatosis by Monte Carlo simulations.

Published in:

NMR in Biomedicine, 2025, v. 38, n. 1, p. 1, doi. 10.1002/nbm.5274

By:

Ma, Mengyuan;
Cheng, Junying;
Li, Xiaoben;
Fan, Zhuangzhuang;
Wang, Changqing;
Reeder, Scott B.;
Hernando, Diego

Publication type:

Article

Simulation of a virtual liver iron overload model and R<sub>2</sub>* estimation using multispectral fat–water models for GRE and UTE acquisitions at 1.5 T and 3 T.

Published in:

NMR in Biomedicine, 2023, v. 36, n. 12, p. 1, doi. 10.1002/nbm.5018

By:

Neupane, Prasiddhi;
Shrestha, Utsav;
Brasher, Sarah;
Abramson, Zachary;
Tipirneni‐Sajja, Aaryani

Publication type:

Article

The influence of iron on bone metabolism disorders.

Published in:

Osteoporosis International, 2024, v. 35, n. 2, p. 243, doi. 10.1007/s00198-023-06937-x

By:

Zhang, Hui;
Yang, Fan;
Cao, Zihou;
Xu, Youjia;
Wang, Mingyong

Publication type:

Article

Relationship between Hepcidin and Iron in Diabetes Mellitus and Liver Disorders:Review artical.

Published in:

Zagazig University Medical Journal, 2025, v. 31, n. 4, p. 1666, doi. 10.21608/zumj.2025.361744.3848

By:

EL-Sayed Abulmagd, Mariem Yousry;
EL-Sadawy, Hamad Amin;
EL-Belbasi, Hussein Ibraheim

Publication type:

Article

Magnetic Resonance Imaging Evaluation of Myocardial and Hepatic Iron Overload in Beta-Thalassaemia.

Published in:

Zagazig University Medical Journal, 2024, v. 30, n. 8, p. 4564, doi. 10.21608/ZUMJ.2024.263788.3123

By:

Tantawy, Heba F.;
Abdalla, Esraa A.;
shawky, Khalid M.;
Abdelhamed, Marwa

Publication type:

Article

The Impact of Genotype on Bone Complications in Beta Thalassemia Major Patients.

Published in:

Zagazig University Medical Journal, 2024, v. 30, n. 3, p. 935, doi. 10.21608/ZUMJ.2023.189467.2731

By:

Abdo, Ali A.;
Beshir, Mohamed R.;
Hassan, Tamir A.;
Mohamed, Amr A.

Publication type:

Article

Talasemi Majör Hastalarında MRG ile Kardiyak Demir Yükü Ölçümü, Demir Yükünün Kardiyak Fonksiyonlara Etkisinin Değerlendirilmesi ve Doku Doppleri ile Karşılaştırılması

Published in:

Istanbul Gelisim University Journal of Health Sciences / İstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi, 2024, n. 22, p. 81, doi. 10.38079/igusabder.1362022

By:

GÜZELBEY, Tevfik;
GÜRSES, Bengi;
SARSILMAZ, Aysegül;
KARASU, Ebru;
ÖZVEREN, Olcay;
AYDIN, Yusuf Sinan

Publication type:

Article

Hemojuvelin deficiency promotes liver mitochondrial dysfunction and predisposes mice to hepatocellular carcinoma.

Published in:

Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-03108-2

By:

Allameh, Abdolamir;
Hüttmann, Nico;
Charlebois, Edouard;
Katsarou, Angeliki;
Gu, Wen;
Gkouvatsos, Konstantinos;
Pasini, Elisa;
Bhat, Mamatha;
Minic, Zoran;
Berezovski, Maxim;
Guido, Maria;
Fillebeen, Carine;
Pantopoulos, Kostas

Publication type:

Article